Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits

Authors

• Emma C Johnson, Washington University School of Medicine in St. Louis
• Jared V Balbona, Washington University School of Medicine in St. Louis
• Alexander S Hatoum, Washington University School of Medicine in St. Louis
• David A A Baranger, Washington University School of Medicine in St. Louis
• Louis Fox, Washington University School of Medicine in St. Louis
• Paul W Jeffries, Washington University School of Medicine in St. Louis
• Laura J Bierut, Washington University School of Medicine in St. Louis
• Andrew C Heath, Washington University School of Medicine in St. Louis
• Pamela A Madden, Washington University School of Medicine in St. Louis
• Elliot C Nelson, Washington University School of Medicine in St. Louis
• Arpana Agrawal, Washington University School of Medicine in St. Louis
• et al.

Journal

Psychological Medicine

Publication Date

8-20-2025

Volume

55

First Page

e234

Document Type

Open Access Publication

DOI

10.1017/S0033291725100883

Rights and Permissions

Johnson EC, Lai D, Balbona JV, Miller AP, Hatoum AS, Deak JD, Jennings M, Baranger DAA, Galimberti M, Sanichwankul K, Thorgeirsson T, Colbert SMC, Adhikari K, Docherty AR, Degenhardt L, Edwards T, Fox L, Giannelis A, Jeffries PW, Korhonen T, Morrison CL, Nunez YZ, Palviainen T, Su MH, Romero Villela PN, Wetherill L, Willoughby EA, Zellers SM, Bierut LJ, Buchwald J, Copeland WE, Corley RP, Friedman NP, Foroud TM, Gillespie NA, Gizer IR, Heath AC, Hickie IB, Kaprio J, Keller MC, Lee JJ, Lind P, Madden PA, Maes HHM, Martin NG, McGue M, Medland SE, Nelson EC, Pearson J, Porjesz B, Stallings MC, Vrieze S, Wilhelmson KC, Kranzler HR, Walters RK, Polimanti R, Malison R, Zhou H, Stefansson K, Sanchez-Roige S, Potenza M, Mutirangura A, Shotelersuk V, Kalayasiri R, Edenberg HJ, Gelernter J, Agrawal A. Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med. 2025 Aug 20;55:e234. doi: 10.1017/S0033291725100883. PMID: 40831304; PMCID: PMC12360691. © The Author(s), 2025. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercialShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons license is used to distribute the re-used or adapted article and the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use.

Recommended Citation

Johnson, Emma C; Balbona, Jared V; Hatoum, Alexander S; Baranger, David A A; Fox, Louis; Jeffries, Paul W; Bierut, Laura J; Heath, Andrew C; Madden, Pamela A; Nelson, Elliot C; Agrawal, Arpana; and et al., "Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits." Psychological Medicine. 55, e234 (2025).
https://digitalcommons.wustl.edu/oa_4/6993

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.