A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects

Authors

Soumen Chakraborty, Washington University School of Medicine in St. Louis
Abdelfattah Faouzi, Washington University School of Medicine in St. Louis
Sarah M Bernhard, Washington University School of Medicine in St. Louis
Nitin Nuthikattu, Washington University School of Medicine in St. Louis
Rahul Jilakara, Washington University School of Medicine in St. Louis
Satyanarayana M Chintala, Washington University School of Medicine in St. Louis
Tao Che, Washington University School of Medicine in St. Louis
Susruta Majumdar, Washington University School of Medicine in St. Louis
et al

Journal

Journal of medicinal chemistry

Publication Date

9-23-2021

Volume

64

Issue

18

First Page

13873

Last Page

13892

Document Type

Open Access Publication

DOI

10.1021/acs.jmedchem.1c01273

Rights and Permissions

Chakraborty S, DiBerto JF, Faouzi A, Bernhard SM, Gutridge AM, Ramsey S, Zhou Y, Provasi D, Nuthikattu N, Jilakara R, Nelson MNF, Asher WB, Eans SO, Wilson LL, Chintala SM, Filizola M, van Rijn RM, Margolis EB, Roth BL, McLaughlin JP, Che T, Sames D, Javitch JA, Majumdar S. A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects. J Med Chem. 2021 Sep 23;64(18):13873-13892. doi: 10.1021/acs.jmedchem.1c01273. Copyright © 2021 The Authors. CC-BY-NC-ND

Recommended Citation

Chakraborty, Soumen; Faouzi, Abdelfattah; Bernhard, Sarah M; Nuthikattu, Nitin; Jilakara, Rahul; Chintala, Satyanarayana M; Che, Tao; Majumdar, Susruta; and et al, "A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects." Journal of medicinal chemistry. 64, 18. 13873 - 13892. (2021).
https://digitalcommons.wustl.edu/oa_4/70