Sclerostin deficiency sensitizes white adipocytes to thermogenic signals that induce beiging in mice

Authors

• Gillian M Choquette, University of Maryland at Baltimore
• Soohyun P Kim, Johns Hopkins University
• Kevin J Wilkinson, University of Maryland at Baltimore
• Belen C Avelar, University of Maryland at Baltimore
• Sushrut Pathy, University of Maryland at Baltimore
• Zhu Li, University of Maryland at Baltimore
• Jasmine Wu, University of Maryland at Baltimore
• Susan Aja, Johns Hopkins University
• Daniel L J Thorek, Washington University School of Medicine in St. Louis
• Michael J Wolfgang, Johns Hopkins University
• Ryan C Riddle, University of Maryland at Baltimore

Journal

Nature Communications

Publication Date

2-5-2026

Volume

17

Issue

1

First Page

2394

Document Type

Open Access Publication

DOI

10.1038/s41467-026-69227-0

Rights and Permissions

Choquette, G.M., Kim, S.P., Wilkinson, K.J. et al. Sclerostin deficiency sensitizes white adipocytes to thermogenic signals that induce beiging in mice. Nat Commun 17, 2394 (2026). https://doi.org/10.1038/s41467-026-69227-0 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Choquette, Gillian M; Kim, Soohyun P; Wilkinson, Kevin J; Avelar, Belen C; Pathy, Sushrut; Li, Zhu; Wu, Jasmine; Aja, Susan; Thorek, Daniel L J; Wolfgang, Michael J; and Riddle, Ryan C, "Sclerostin deficiency sensitizes white adipocytes to thermogenic signals that induce beiging in mice." Nature Communications. 17, 1. 2394 (2026).
https://digitalcommons.wustl.edu/oa_4/7142

Additional Links

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