Novel insights into early Alzheimer's disease: Quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology

Authors

• Satya V V N Kothapalli, Washington University School of Medicine in St. Louis
• Tammie L S Benzinger, Washington University School of Medicine in St. Louis
• Randall J Bateman, Washington University School of Medicine in St. Louis
• Melody Li, Washington University School of Medicine in St. Louis
• Cihat Eldeniz, Washington University School of Medicine in St. Louis
• John C Morris, Washington University School of Medicine in St. Louis
• Dmitriy A Yablonskiy, Washington University School of Medicine in St. Louis

Journal

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Publication Date

1-1-2026

Volume

18

Issue

2

First Page

e70355

Document Type

Open Access Publication

DOI

10.1002/dad2.70355

Rights and Permissions

Kothapalli SVVN, Benzinger TLS, Bateman RJ, et al. Novel insights into early Alzheimer's disease: quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology. Alzheimer's Dement. 2026; 18:e70355. https://doi.org/10.1002/dad2.70355 © 2026 The Author(s). Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals LLC on behalf of Alzheimer's Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Recommended Citation

Kothapalli, Satya V V N; Benzinger, Tammie L S; Bateman, Randall J; Li, Melody; Eldeniz, Cihat; Morris, John C; and Yablonskiy, Dmitriy A, "Novel insights into early Alzheimer's disease: Quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology." Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 18, 2. e70355 (2026).
https://digitalcommons.wustl.edu/oa_4/7235

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.