Therapeutic reprogramming of tumour-associated macrophages in pancreatic cancer using a cytotoxic CCR2-targeted nanotheranostic

Authors

• Vikas Kumar Somani, Washington University School of Medicine in St. Louis
• Xiaohui Zhang, Washington University School of Medicine in St. Louis
• Timothy Hung-Po Chen, Washington University School of Medicine in St. Louis
• Ashenafi Bulle, Washington University School of Medicine in St. Louis
• Sapana Bansod, Washington University School of Medicine in St. Louis
• Lin Li, Washington University School of Medicine in St. Louis
• Yutong Geng, Washington University School of Medicine in St. Louis
• Liang-I Kang, Washington University School of Medicine in St. Louis
• Gyu Seong Heo, Washington University School of Medicine in St. Louis
• Hannah Luehmann, Washington University School of Medicine in St. Louis
• Yuena Zhang, Washington University School of Medicine in St. Louis
• Muhammad A Saeed, Washington University School of Medicine in St. Louis
• Kory J Lavine, Washington University School of Medicine in St. Louis
• David G DeNardo, Washington University School of Medicine in St. Louis
• Russell K Pachynski, Washington University School of Medicine in St. Louis
• Yongjian Liu, Washington University School of Medicine in St. Louis
• Kian-Huat Lim, Washington University School of Medicine in St. Louis

Journal

Molecular cancer

Publication Date

2-7-2026

Volume

25

Issue

1

First Page

65

Document Type

Open Access Publication

DOI

10.1186/s12943-026-02597-7

Rights and Permissions

Somani, V.K., Zhang, X., Chen, T.HP. et al. Therapeutic reprogramming of tumour-associated macrophages in pancreatic cancer using a cytotoxic CCR2-targeted nanotheranostic. Mol Cancer 25, 65 (2026). https://doi.org/10.1186/s12943-026-02597-7 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Somani, Vikas Kumar; Zhang, Xiaohui; Chen, Timothy Hung-Po; Bulle, Ashenafi; Bansod, Sapana; Li, Lin; Geng, Yutong; Kang, Liang-I; Heo, Gyu Seong; Luehmann, Hannah; Zhang, Yuena; Saeed, Muhammad A; Lavine, Kory J; DeNardo, David G; Pachynski, Russell K; Liu, Yongjian; and Lim, Kian-Huat, "Therapeutic reprogramming of tumour-associated macrophages in pancreatic cancer using a cytotoxic CCR2-targeted nanotheranostic." Molecular cancer. 25, 1. 65 (2026).
https://digitalcommons.wustl.edu/oa_4/7304

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.