Moderators of antidepressant augmentation versus switch in the OPTIMUM randomised controlled trial

Authors

• Helena K Kim, University of Toronto
• Jordan F Karp, University of Arizona
• Helen Lavretsky, University of California, Los Angeles
• Daniel M Blumberger, University of Toronto
• Patrick J Brown, Columbia University
• Alastair J Flint, University of Toronto
• Emily Lenard, Washington University School of Medicine in St. Louis
• J Philip Miller, Washington University School of Medicine in St. Louis
• Charles F Reynolds, University of Pittsburgh
• Steven P Roose, Columbia University
• Eric J Lenze, Washington University School of Medicine in St. Louis
• Benoit H Mulsant, University of Toronto

Journal

The British Journal of Psychiatry

Publication Date

11-1-2025

Volume

227

Issue

5

First Page

790

Last Page

797

Document Type

Open Access Publication

DOI

10.1192/bjp.2025.125

Rights and Permissions

Kim HK, Karp JF, Lavretsky H, Blumberger DM, Brown PJ, Flint AJ, Lenard E, Miller JP, Reynolds CF, Roose SP, Lenze EJ, Mulsant BH. Moderators of antidepressant augmentation versus switch in the OPTIMUM randomised controlled trial. Br J Psychiatry. 2025 Nov;227(5):790-797. doi: 10.1192/bjp.2025.125. Epub 2025 Jun 19 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. © The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists

Recommended Citation

Kim, Helena K; Karp, Jordan F; Lavretsky, Helen; Blumberger, Daniel M; Brown, Patrick J; Flint, Alastair J; Lenard, Emily; Miller, J Philip; Reynolds, Charles F; Roose, Steven P; Lenze, Eric J; and Mulsant, Benoit H, "Moderators of antidepressant augmentation versus switch in the OPTIMUM randomised controlled trial." The British Journal of Psychiatry. 227, 5. 790 - 797. (2025).
https://digitalcommons.wustl.edu/oa_4/7311

Department

ICTS (Institute of Clinical and Translational Sciences)