Natural history of 15 patients with autosomal dominant WFS1 pathogenic variants associated with sensorineural hearing loss and optic atrophy

Authors

• Jessica P Roberts, Washington University School of Medicine in St. Louis
• Abby F Tang, Washington University School of Medicine in St. Louis
• Daniela Hernandez, Washington University School of Medicine in St. Louis
• Brianna Carman, Washington University School of Medicine in St. Louis
• Liam Oiknine, Washington University School of Medicine in St. Louis
• Cris Brown, Washington University School of Medicine in St. Louis
• Stacy Hurst, Washington University School of Medicine in St. Louis
• Yunshuo Tang, Washington University School of Medicine in St. Louis
• Fumihiko Urano, Washington University School of Medicine in St. Louis

Journal

Orphanet Journal of Rare Diseases

Publication Date

4-18-2026

Volume

21

Issue

1

First Page

210

Document Type

Open Access Publication

DOI

10.1186/s13023-026-04348-9

Rights and Permissions

Roberts, J.P., Tang, A.F., Hernandez, D. et al. Natural history of 15 patients with autosomal dominant WFS1 pathogenic variants associated with sensorineural hearing loss and optic atrophy. Orphanet J Rare Dis 21, 210 (2026). https://doi.org/10.1186/s13023-026-04348-9 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Recommended Citation

Roberts, Jessica P; Tang, Abby F; Hernandez, Daniela; Carman, Brianna; Oiknine, Liam; Brown, Cris; Hurst, Stacy; Tang, Yunshuo; and Urano, Fumihiko, "Natural history of 15 patients with autosomal dominant WFS1 pathogenic variants associated with sensorineural hearing loss and optic atrophy." Orphanet Journal of Rare Diseases. 21, 1. 210 (2026).
https://digitalcommons.wustl.edu/oa_4/7373

Department

ICTS (Institute of Clinical and Translational Sciences)