Issue Date

2015

Abstract

Spatial origins of compound action potential responses to varying stimulation rates, frequencies, and levels were investigated. A technique to measure the regions in the cochlea generating each response in which a neurotoxic drug (kainic acid) is slowly injected into the cochlear apex was used. This induces a progressive ablation of responses from apex (low frequency) to base (high frequency), allowing the spatial origins of cochlear responses to be quantified.

Language

English

Publisher

Program in Audiology and Communication Sciences, Washington University School of Medicine

Subject (MeSH)

Action Potentials; Cochlea; Ear, Inner

Document Type

Thesis

Advisor

Salt, Alec

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