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Submissions from 2011

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Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, and Michael S. Diamond

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Targeting HTLV-1 Activation of NFκB in Mouse Models and ATLL Patients, Daniel A. Rauch and Lee Ratner

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IL-15 deficiency promotes tumor growth in tax transgenic mice, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner

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Tet-inducible lymphoma in a new Tax transgenic mouse model, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner

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The effects of XMRV gene expression on the mouse prostate, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner

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A dual role for A-type lamins in DNA double-strand break repair, Abena B. Redwood, Stephanie M. Perkins, Robert P. Vanderwaal, Zhihui Feng, Kenneth J. Biehl, Ignacio Gonzalez-Suarez, Lucia Morgado-Palacin, Wei Shi, Julien Sage, Joseph L. Roti-Roti, Colin L. Stewart, Junran Zhang, and Susana Gonzalo

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A behavioral analysis of spatial neglect and its recovery after stroke, Jennifer Rengachary, Biyu J. He, Gordon L. Shulman, and Maurizio Corbetta

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What's new in orthopaedic trauma, William M. Ricci, Christopher McAndrew, David Merriman, and Michael J. Gardner

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Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin, Nicole C. Riddle, Sarah C.R. Elgin, and et al

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Engraftment of cells from porcine islets of Langerhans following transplantation of pig pancreatic primordia in non-immunosuppressed diabetic rhesus macaques, Sharon A. Rogers, Piyush Tripathi, Thalachallour Mohanakumar, Helen Liapis, Feng Chen, Michael R. Talcott, Chad Faulkner, and Marc R. Hammerman

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Muco-cutaneous leishmaniasis in the New World: The ultimate subversion, Catherine Ronet, Stephen M. Beverley, and Nicolas Fasel

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New tools and methods for direct programmatic access to the dbSNP relational database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, and John P. Rice

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Role of guanylyl cyclase modulation in mouse cone phototransduction, Keisuke Sakurai, Jeannie Chen, and Vladimir J. Kefalov

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Cerebral infarction following a seizure in a patient with subarachnoid hemorrhage complicated by delayed cerebral ischemia, Tomoko Rie Sampson, Rajat Dhar, and Gregory J. Zipfel

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Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer, Cesar G. Sanchez, Cynthia X. Ma, Robert J. Crowder, Therese Guintoli, Chanpheng Phommaly, Feng Gao, Li Lin, and Matthew J. Ellis

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Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, and William E. Gillanders

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Year in review 2010: Critical Care- neurocritical care, Michael T. Scalfani and Michael N. Diringer

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A test for common genetic and environmental vulnerability to depression and diabetes, Jeffrey F. Scherrer, Hong Xian, Patrick J. Lustman, Carol E. Franz, Jeanne McCaffery, Michael J. Lyons, Kristen C. Jacobsen, and William S. Kremen

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Application of Bayesian network structure learning to identify causal variant SNPs from resequencing data, Christopher E. Schlosberg, Tae-Hwi Schwantes-An, Weimin Duan, and Nancy L. Saccone

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Mouse models of graft-versus-host disease: advances and limitations, Mark A. Schroder and John F. DiPersio

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Deriving measures of intensive care unit antimicrobial use from computerized pharmacy data: Methods, validation, and overcoming barriers, David N. Schwartz, R Scott Evans, Bernard C. Camins, Yosef M. Khan, James F. Lloyd, Nadine Shehab, Kurt Stevenson, and Centers for Disease Control and Prevention Epicenter Program

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Integrase inhibitors effective against human T-cell leukemia virus type 1, Muhammad E. Seegulam and Lee Ratner

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Integrase inhibitors effective against human T-cell leukemia virus type 1, Muhammad Esa Seegulam and Lee Ratner

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Episodic memory retrieval, parietal cortex, and the default mode network: Functional and topographic analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, and Gordon L. Shulman

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Assessing the optimal definition of oligohydramnios associated with adverse neonatal outcomes, Anthony Shanks, Methodius Tuuli, Caren Schaecher, Anthony O. Odibo, and Roxane Rampersad

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Evaluation of the toxicity of triamcinolone acetonide and dexamethasone sodium phosphate on human lens epithelial cells (HLE B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, and Baruch D. Kuppermann

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CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, and et al.

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APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42, Yvette I. Sheline, John C. Morris, Abraham Z. Synder, Joseph L. Price, Zhizi Yan, Gina D'Angelo, Collin Liu, Sachin Dixit, Tammie Benzinger, Anne Fagan, Alison Goate, and Mark A. Mintun

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Enriching rare variants using family-specific linkage information, Gang Shi, Jeannette Simino, and Dabeeru C. Rao

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Highwire regulates guidance of sister axons in the drosophila mushroom body, Jung Eun Shin and Aaron DiAntonio

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Exploring patient-provider interactions in a Native American community, Vanessa Watts Simonds, Suzanne Christopher, Thomas D. Sequist, Graham A. Colditz, and Rima E. Rudd

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A rapid communication from the AAPM Task Group 201: Recommendations for the QA of external beam radiotherapy data transfer. AAPM TG 201: Quality assurance of external beam radiotherapy data transfer, R. Alfredo Siochi, Peter Balter, Charles D. Bloch, Lakshmi Santanam, Kurt Blodgett, Bruce H. Curran, Martijn Engelsman, Wenzheng Feng, Jim Mechalakos, Dan Pavord, Tom Simon, Steven Sutlief, and X. Ronald Zhu

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Evolutionarily divergent, unstable filamentous actin Is essential for gliding motility in spicomplexan parasites, Kristen M. Skillman, Karthikeyan Diraviyam, Asis Khan, Keliang Tang, David Sept, and L. David Sibley

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Video-rate fluorescence diffuse optical tomography for in vivo sentinel lymph node imaging, Metasebya Solomon, Brian R. White, Ralph E. Nothdruft, Walter Akers, Gail Sudlow, Adam T. Eggebrecht, Samuel Achilefu, and Joseph P. Culver

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A sensitive high-throughput assay for evaluating host-pathogen interactions in cryptococcus neoformans infection, Deepa Srikanta, Meng Yang, Matthew Williams, and Tamara L. Doering

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Catalytic and non-catalytic roles for the Mono-ADP-Ribosyltransferase Arr in the mycobacterial DNA damage response, Christina L. Stallings, Linda Chu, Lucy X. Li, and Michael S. Glickman

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CarD: A new RNA polymerase modulator in mycobacteria, Christina L. Stallings and Michael S. Glickman

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Crohn disease: A current perspective on genetics, autophagy and immunity, Thaddeus S. Stappenbeck, John D. Rioux, Atsushi Mizoguchi, Tatsuya Saitoh, Alan Huett, Arlette Darfeuille-Michaud, Tom Wileman, Noboru Mizushima, Simon Carding, Shizuo Akira, Miles Parkes, and Ramnik J. Xavier

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Oral acyclovir suppression and neurodevelopment after neonatal herpes, Gregory Storch and et al

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Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning, Melissa D. Stuchell-Brereton, Amanda Siglin, Jun Li, Jeffrey K. Moore, Shubbir Ahmed, John C. Williams, and John A. Cooper

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RNA binding protein CUGBP2/CELF2 mediates curcumin- induced mitotic catastrophe of pancreatic cancer cells, Dharmalingam Subramaniam, Satish Ramalingam, David C. Linehan, Brian K. Dieckgraefe, Russell G. Postier, Courtney W. Houchen, Roy A. Jensen, and Shrikant Anant

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Application of collapsing methods for continuous traits to the Genetic Analysis Workshop 17 exome sequence data, Yun Ju Sung, Treva K. Rice, and Dabeeru C. Rao

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Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration, Siobhan Sutcliffe, Remington L. Nevin, Ratna Pakpahan, Debra J. Elliott, Stephen R. Cole, Angelo M. De Marzo, Charlotte A. Gaydos, William B. Isaacs, William G. Nelson, Lori J. Sokoll, Johnathan M. Zenilman, Steven B. Cersovsky, and Elizabeth A. Platz

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Changes in events alter how people remember recent information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, and Jeffrey M. Zacks

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Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, and Marco Colonna

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Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3beta independent of JNK activation, Katsuya Tanabe, Yang Liu, Syed D. Hasan, Sara C. Martinez, Corentin Cras-Meneur, Cris M. Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J. Rhodes, Erik Zmuda, Tsonwin Hai, Nada A. Abumrad, and M. Alan Permutt

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Targeting protein-protein interactions for parasite control, Christina M. Taylor, Kerstin Fischer, Sahar Abubucker, Zhengyuan Wang, John Martin, Daojun Jiang, Marc Magliano, Marie-Noelle Rosso, Ben-Wen Li, Peter U. Fischer, and Makedonka Mitreva

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Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis, Dick Terwel, Knut R. Steffensen, Philip B. Verghese, Markus P. Kummer, Jan-Åke Gustafsson, David M. Holtzman, and Michael T. Heneka

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Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities, Hien T. Tran, Frank M. LaFerla, David M. Holtzman, and David L. Brody

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Statistical analysis and interpretation of prenatal diagnostic imaging studies, part 2: Descriptive and inferential statistical methods, Methodius G. Tuuli and Anthony O. Odibo

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Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medicalfood on pre-eclampsia in high risk population: Randomised controlled trial, Felipe Vadillo-Ortega, Otilia Perichant-Perera, Salvador Espino, Marco Antonio Avila-Vergara, Isabel Ibarra, Roberto Ahued, Myrna Godines, Samuel Parry, George Macones, and Jerome F. Strauss

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bop5 mutations reveal new roles for the IC138 phosphoprotein in the regulation of flagellar motility and asymmetric waveforms, Kristyn E. VanderWaal, Ryosuke Yamamoto, Ken-ichi Wakabayashi, Laura Fox, Ritsu Kamiya, Susan K. Dutcher, Phillip V. Bayly, Winfield S. Sale, and Mary E. Porter

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Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus, Cassandra VanDunk, Lindsay A. Hunter, and Paul A. Gray

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Laparoscopic sleeve gastrectomy versus laparoscopic adjustable gastric banding for the treatment severe obesity in high risk patients, J. Esteban Varela

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Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, and John R. Cirrito

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Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense, R. Robert Vethanayagam, Nikolaos G. Almyroudis, Melissa J. Grimm, David C. Lewandowski, Christine T. N Pham, Timothy S. Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J. Walsh, Constantin F. Urban, and Brahm H. Segal

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MicroRNAs modulate schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, and Jeffrey Milbrandt

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Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function, Andreu Viader, Judith P. Golden, Robert H. Baloh, Robert E. Schmidt, Daniel A. Hunter, and Jeffrey Milbrandt

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Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction, Andreu Viader, Elizabeth C. Wright-Jin, Bhupinder P.S Vohra, Robert O. Heuckeroth, and Jeffrey Milbrandt

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Weight loss, exercise, or both and physical function in obese older adults, Dennis T. Villareal, Suresh Chode, Nehu Parimi, David R. Sinacore, Krupa Shah, Tiffany Hilton, Reina Armamento-Villareal, Nicola Napoli, and Clifford Qualls

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Phr1 is required for proper retinocollicular targeting of nasal-dorsal retinal ganglion cells, Bradley Q. Vo, A J. Bloom, and Susan M. Culican

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Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy, Arpita Kalla Vyas, Kai-Chen Yang, Dennis Woo, Anatoly Tzekov, Attila Kovacs, Patrick Y. Jay, and Paul W. Hruz

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Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins, Haoyi Wang, David Mayhew, Xuhua Chen, Mark Johnston, and Robi David Mitra

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Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles, Jianbin Wang, Benjamin Czech, Amanda Crunk, Adam Wallace, Makedonka Mitreva, Gregory J. Hannon, and Richard E. Davis

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Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women, Xuewen Wang and Barbara J. Nicklas

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Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression, Lukas D. Wartman, David E. Larson, Zhifu Xiang, Li Ding, Ken Chen, Ling Lin, Patrick Cahan, Jeffery M. Klco, John S. Welch, Cheng Li, Jacqueline E. Payton, Geoffrey L. Uy, Nobish Varghese, Rhonda E. Ries, and et al.

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Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling, Marcus Watkins, Susan K. Grimston, Jin Yi Norris, Bertrand Guillotin, Angela Shaw, Elia Beniash, and Roberto Civitelli

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Catheter-associated Nocardia higoensis bacteremia in a child with acute lymphocytic leukemia, Michael E. Watson Jr., Michele M. Eastabrook, and Carey-Ann D. Burnham

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Photo Quiz: A 2-year-old female with fever and rash, Michael E. Watson Jr., Gregory A. Storch, W. Michael Dunne Jr., and Carey-Ann D. Burnham

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Profile of ezogabine (retigabine) and its potential as an adjunctive treatment for patients with partial-onset seizures, Judith L.Z Weisenberg and Michael Wong

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Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans, Edward P. Weiss, Dennis T. Villareal, Luigi Fontana, Dong-Ho Han, and John O. Holloszy

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The duration of diarrhea and fever is associated with growth faltering in rural Malawian children aged 6-18 months, Ariana Weisz, Gus Meuli, Chrissie Thakwalakwa, Indi Trehan, Kenneth Maleta, and Mark Manary

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PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice, John S. Welch, Wenlin Yuan, and Timothy J. Ley

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The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance, Yi-Lan Weng, Nan Liu, Aaron DiAntonio, and Heather T. Broihier

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The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens, Luke A. Wiley, Ramya Rajagopal, Lisa K. Dattilo, and David C. Beebe

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Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study, Nathan E. Wineinger, Amit Patki, Kristin J. Meyers, Ulrich Broeckel, Charles C. Gu, DC Rao, Richard B. Devereux, Donna K. Arnett, and Herman K. Tiwari

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Risk estimates from an online risk calculator are more believable and recalled better when expressed as integers, Holly O. Witteman, Brian J. Zikmund-Fisher, Erika A. Waters, Teresa Gavaruzzi, and Angela Fagerlin

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Electronic surveillance for healthcare-associated central line-associated bloodstream infections outside the intensive care unit, Keith F. Woeltje, Kathleen M. McMullen, Anne M. Butler, Ashleigh J. Goris, and Joshua A. Doherty

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Lipoprotein Lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS, Alexis C. Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, and Donna K. Arnett

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A monthly quality assurance procedure for 3D surface imaging, H. Omar Wooten, Eric E. Klein, Garima Gokrhoo, and Lakshmi Santanam

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RhoA protects the mouse heart against ischemia/reperfusion injury, Sunny Yang Xiang, Davy Vanhoutte, Dominic P. Del Re, Nicole H. Purcell, Haiyun Ling, Indroneal Banerjee, Julie Bossuyt, Richard A. Lang, Yi Zheng, Scot J. Matkovich, Shigeki Miyamoto, Jeffrey D. Molkentin, Gerald W. Dorn II, and Joan Heller Brown

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Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, and et al

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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice, Kaoru Yamada, John R. Cirrito, Floy R. Stewart, Hong Jiang, Mary Beth Finn, Brandon B. Holmes, Lester I. Binder, Eva-Maria Mandelkow, Marc I. Diamond, Virginia M.-Y. Lee, and David M. Holtzman

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Binocular disparity tuning and visual–vestibular congruency of multisensory neurons in macaque parietal cortex, Yun Yang, Sheng Liu, Syed A. Chowdhury, Gregory C. DeAngelis, and Dora E. Angelaki

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A vertebrate case study of the quality of assemblies derived from next-generation sequences, Liang Ye, LaDeana W. Hillier, Patrick Minx, Nay Thane, Devin P. Locke, John C. Martin, Lei Chen, Makedonka Mitreva, Jason R. Miller, Kevin V. Haub, David J. Dooling, Elaine R. Mardis, Richard K. Wilson, George M. Weinstock, and Wesley C. Warren

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Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths, Sachin Yende, Gina D'Angelo, John A. Kellum, Lisa Weissfeld, A. Murat Kaynar, Tammy Young, Kaikobad Irani, and Derek C. Angus

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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise, Tongjian You, Beth L. Disanzo, Xuewen Wang, Rongze Yang, and Dawei Gong

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Prediction error associated with the perceptual segmentation of naturalistic events, Jeffrey M. Zacks, Christopher A. Kurby, Michelle L. Eisenberg, and Nayiri Haroutunian

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mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists, Magda Zammataro, Santina Chiechio, Michael C. Montana, Anna Traficante, Agata Copani, Ferdinando Nicoletti, and Robert W. Gereau IV

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A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data, Lu Zhang, Robert J. A. Bell, Michael A. Kiebish, Thomas N. Seyfried, Xianlin Han, Richard W. Gross, and Jeffrey H. Chuang

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Methods for adjusting population structure and familial relatedness in association test for collective effect of multiple rare variants on quantitative traits, Qunyuan Zhang, Doyoung Chung, Aldi Kraja, Ingrid B. Borecki, and Michael A. Province

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Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair, Shichuan Zhang, Hirohiko Yajima, HoangDinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, and Benjamin P.C. Chen

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Identification of DHX33 as a mediator of rRNA synthesis and cell growth, Yandong Zhang, Jason T. Forys, Alexander P. Miceli, Abigail S. Gwinn, and Jason D. Weber

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Transcriptome analysis of female and male Xiphophorus maculatus Jp 163 A, Ziping Zhang, Yilei Wang, Shuhong Wang, Jingtao Liu, Wesley Warren, Makedonka Mitreva, and Ronald B. Walter

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The genetic sonogram: Comparing the use of likelihood ratios versus logistic regression coefficients for Down syndrome screening, Yan Zhong, Ryan Longman, Rachael Bradshaw, and Anthony O. Odibo

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Pregnancy in multiple system atrophy: A case report, Lirong Zhu, Nigel J. Cairns, Samer D. Tabbal, and Brad A. Racette

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Do shared etiological factors contribute to the relationship between sexual orientation and depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, and M. T. Lynskey

Submissions from 2010

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In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: Early gene expression profiling reveals possible drug target in AML, Anmaar M. Abdul-Nabi, Enas R. Yassin, Nobish Varghese, Hrishikesh Deshmukh, and Nabeel R. Yaseen

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Influenza vaccination among healthcare workers: Ten-year experience of a large healthcare organization, Cristina Ajenjo, Keith F. Woeltje, Hilary M. Babcock, Nancy Gemeinhart, Marilyn Jones, and Victoria J. Fraser

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Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression, Jörn C. Albring, Michelle M. Sandau, Aaron S. Rapaport, Brian T. Edelson, Ansuman Satpathy, Mona Mashayekhi, Stephanie K. Lathrop, Chyi-Song Hsieh, Matthias Stelljes, Marco Colonna, Theresa L. Murphy, and Kenneth M. Murphy