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Submissions from 2021

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Bioactivation of isoxazole-containing bromodomain and extra-terminal domain (BET) inhibitors, Noah R Flynn, Michael D Ward, Mary A Schleiff, Corentine M C Laurin, Rohit Farmer, Stuart J Conway, Gunnar Boysen, S Joshua Swamidass, and Grover P Miller

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Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM, Jerry Fong, Jacob R. Gardner, Jared M. Andrews, Amanda F. Cashen, Jacqueline E. Payton, Kilian Q. Weinberger, and John R. Edwards

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N-cadherin in osteolineage cells modulates stromal support of tumor growth, Francesca Fontana, Jingyu Xiang, Xinming Su, Eric Tycksen, Rachel Nassau, Gregory Fox, Giulia Leanza, Katherine Weilbaecher, and Roberto Civitelli

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Effects of dietary restriction on neuroinflammation in neurodegenerative diseases, Luigi Fontana, Laura Ghezzi, Anne H. Cross, and Laura Piccio

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Addressing cancer survivors' cardiovascular health using the Automated Heart Health Assessment (AH-HA) EHR tool: Initial protocol and modifications to address COVID-19 challenges, Randi E Foraker, Eleanor C Davidson, Emily V Dressler, Brian J Wells, Simon Craddock Lee, Heidi D Klepin, Karen M Winkfield, W Gregory Hundley, Philip R O Payne, Albert M Lai, Glenn J Lesser, and Kathryn E Weaver

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Transmission dynamics: Data sharing in the COVID-19 era, Randi E Foraker, Albert M Lai, Thomas G Kannampallil, Keith F Woeltje, Anne M Trolard, and Philip R O Payne

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Processing pipeline for image reconstructed fNIRS analysis using both MRI templates and individual anatomy, Samuel Forbes, Sobanawartiny Wijeakumar, Adam Eggebrecht, Vincent Magnotta, and John Spencer

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Future directions for HIV service delivery research: Research gaps identified through WHO guideline development, Nathan Ford, Ingrid Eshun-Wilson, Wole Ameyan, Morkor Newman, Lara Vojnov, Meg Doherty, and Elvin Geng

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Prioritization of molecular targets for antimalarial drug discovery, Barbara Forte, Daniel E Goldberg, Eva S Istvan, and et al

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Cognitive correlates of instrumental activities of daily living performance in Parkinson disease without dementia, Erin R Foster and Tasha Doty

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Translating family-based behavioral treatment for childhood obesity into a user-friendly digital package for delivery to low-income families through primary care partnerships: The MO-CORD study, Lauren A. Fowler, Sarah E. Hampl, Meredith L. Dreyer Gillette, Amanda E. Staiano, Chelsea L. Kracht, Andrea K. Graham, Sherri Gabbert, Kelly Springstroh, Fanice Thomas, Lisa Nelson, Aubrie E. Hampp, Jordan A. Carlson, Robinson Welch, Denise E. Wilfley, and The MO-CORD Study Group

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Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice, Michael P Franczyk, Mai He, and Jun Yoshino

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Psychosocial syndemics and multimorbidity in patients with heart failure, Kenneth E Freedland, Judith A Skala, Robert M Carney, Brian C Steinmeyer, and Michael W Rich

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Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism, Jeannine A Frei, Cheryl J Brandenburg, Jonathan E Nestor, Didier M Hodzic, Celine Plachez, Helen McNeill, Derek M Dykxhoorn, Michael W Nestor, Gene J Blatt, and Yu-Chih Lin

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Information content differentiates enhancers from silencers in mouse photoreceptors, Ryan Z. Friedman, David M. Granas, Connie A. Myers, Joseph C. Corbo, Barak A. Cohen, and Michael A. White

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Inflammatory myoglandular polyps presenting with diarrhea, Cassandra D. L. Fritz, Pooja Navale, Matthew Mutch, and Vladimir Kushnir

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Phase 1b study of AVB-500 in combination with paclitaxel or pegylated liposomal doxorubicin platinum-resistant recurrent ovarian cancer, Katherine C Fuh, Michael A Bookman, Joyce F Liu, Robert L Coleman, Thomas J Herzog, Premal H Thaker, Bradley J Monk, Randy Anderson, Gail McIntyre, Reshma Rangwala, and Kathleen N Moore

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Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis, Kristen E Funk, Artem D Arutyunov, Pritesh Desai, James P White, Allison L Soung, Sarah F Rosen, Michael S Diamond, and Robyn S Klein

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Enhancing dopamine tone modulates global and local cortical perfusion as a function of COMT Val158Met genotype, Daniella J Furman, Ioannis Pappas, Robert L White 3rd, Andrew S Kayser, and Mark D'Esposito

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Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress, Yong Fu, Kevin M. Brown, Nathaniel G. Jones, Silvia N.J. Moreno, and L. David Sibley

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The ideological divide in confidence in science and participation in medical research, Matthew Gabel, Jonathan Gooblar, Catherine M. Roe, and John C. Morris

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Defining phenotypic and functional heterogeneity of glioblastoma stem cells by mass cytometry, Luciano Galdieri, Arijita Jash, Olga Malkova, Diane D Mao, Patrick DeSouza, Yunli E Chu, Amber Salter, Jian L Campian, Kristen M Naegle, Cameron W Brennan, Hiroaki Wakimoto, Stephen T Oh, Albert H Kim, and Milan G Chheda

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What’s wrong with this picture? A critical review of current Centers for Medicare & Medicaid Services coverage criteria for continuous glucose monitoring, Rodolfo J. Galindo, Christopher G. Parkin, Grazia Aleppo, Anders L. Carlson, Davida F. Kruger, Carol J. Levy, Guillermo E. Umpierrez, and Janet B. McGill

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Brown adipose tissue monocytes support tissue expansion, Alexandre Gallerand, Hannah P. Luehmann, Deborah H. Sultan, Yongjian Liu, and et al

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Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences, Liron Ganel, Lei Chen, Ryan Christ, Erica Young, Indraniel Das, Krishna Kanchi, David Larson, Allison Regier, Haley Abel, Chul Joo Kang, Alexandra Scott, Adam Locke, Nathan O Stitziel, Ira M Hall, and et al

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TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons, Daxing Gao, Michael S Diamond, and et al

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Fractal motor activity regulation and sex differences in preclinical Alzheimer's disease pathology, Lei Gao, Peng Li, Arlen Gaba, Erik Musiek, Yo-El S Ju, and Kun Hu

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Irradiation-modulated murine brain microenvironment enhances GL261-tumor growth and inhibits anti-PD-L1 immunotherapy, Joel R Garbow, Tanner M Johanns, Xia Ge, John A Engelbach, Liya Yuan, Sonika Dahiya, Christina I Tsien, Feng Gao, Keith M Rich, and Joseph J H Ackerman

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Genetics and molecular pathogenesis of human hydrocephalus, Maria Garcia-Bonilla, James P. McAllister, and David D. Limbrick

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A systematic review of higher-risk myelodysplastic syndromes clinical trials to determine the benchmark of azacitidine and explore alternative endpoints for overall survival, Jacqueline S Garcia, Ronan T Swords, Gail J Roboz, Meagan A Jacoby, Guillermo Garcia-Manero, Wan-Jen Hong, Xiaoqing Yang, Ying Zhou, Uwe Platzbecker, David P Steensma, Johannes E Wolff, and Pierre Fenaux

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Detecting risk level in individuals misusing fentanyl utilizing posts from an online community on Reddit, Sanjana Garg, Jordan Taylor, Mai El Sherief, Erin Kasson, Talayeh Aledavood, Raven Riordan, Nina Kaiser, Patricia Cavazos-Rehg, and Munmun De Choudhury

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A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity, Caroline E Geisler, Susma Ghimire, Stephanie M Bruggink, Kendra E Miller, Savanna N Weninger, Jason M Kronenfeld, Jun Yoshino, Samuel Klein, Frank A Duca, and Benjamin J Renquist

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Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release, Caroline E Geisler, Susma Ghimire, Chelsea Hepler, Kendra E Miller, Stephanie M Bruggink, Kyle P Kentch, Mark R Higgins, Christopher T Banek, Jun Yoshino, Samuel Klein, and Benjamin J Renquist

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Doctor as street-level bureaucrat, Elvin H. Geng

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Outcomes associated with social distancing policies in St Louis, Missouri, during the early phase of the COVID-19 pandemic, Elvin H. Geng, Joshua Schwab, Randi Foraker, Branson Fox, Christine M. Hoehner, Mario Schootman, Aaloke Mody, William Powderly, Byron Yount, Keith Woeltje, and Maya Petersen

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Implications of oligomeric amyloid-beta (oAβ42) signaling through α7β2-nicotinic acetylcholine receptors (nAChRs) on basal forebrain cholinergic neuronal intrinsic excitability and cognitive decline, Andrew A George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Heather A Bimonte-Nelson, Marina R Picciotto, Ronald J Lukas, and Paul Whiteaker

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The epidemiology and biology of pulmonary metastases, William D Gerull, Varun Puri, and Benjamin D Kozower

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Targeting the gut to treat multiple sclerosis, Laura Ghezzi, Claudia Cantoni, Gabriela V Pinget, Yanjiao Zhou, and Laura Piccio

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A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection, Nicole M Gilbert, Brian Choi, Jingjie Du, Christina Collins, Amanda L Lewis, Catherine Putonti, and Alan J Wolfe

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Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice, Nicole M Gilbert, Lynne R Foster, Bin Cao, Yin Yin, Indira U Mysorekar, and Amanda L Lewis

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Elevated MICs of susceptible antipseudomonal cephalosporins in non-carbapenemase-producing, carbapenem-resistant Pseudomonas aeruginosa: Implications for dose optimization, Christian M Gill, Carey-Ann D Burnham, and et al

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Caregiver health-related quality of life, burden, and patient outcomes in ambulatory advanced heart failure: A report from REVIVAL, Nisha A Gilotra, Douglas L Mann, and et al

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Association between diagnosis code expansion and changes in 30-day risk-adjusted outcomes for cardiovascular diseases, Lauren Gilstrap, Rishi K Wadhera, Andrea M Austin, Stephen Kearing, Karen E Joynt Maddox, and Robert W Yeh

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Reproducibility of hospital rankings based on centers for Medicare & Medicaid Services Hospital Compare measures as a function of measure reliability, Laurent G. Glance, David R. Nerenz, Karen E. Joynt Maddox, Bruce L. Hall, and Andrew W. Dick

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Abaloparatide real-world patient experience study, Deborah T Gold, Richard Weiss, Tammy Beckett, Chad Deal, Robert S Epstein, Andrew L James, Jacqueline M Kernaghan, Mahshid Mohseni, Michael Spiegel, Tamara Vokes, Jenna Roberts, Tom Bailey, Yamei Wang, and Setareh A Williams

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Use of a risk analytic algorithm to inform weaning from vasoactive medication in patients following pediatric cardiac surgery, Michael P. Goldsmith, Vinay M. Nadkarni, Craig Futterman, Avihu Z. Gazit, Dimitar Baronov, Adam Tomczak, Peter C. Laussen, and Joshua W. Salvin

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Development and testing of a spray-dried tuberculosis vaccine candidate in a mouse model, Mellissa Gomez, Mushtaq Ahmed, Shibali Das, Leah Mellett, Rosemary Swanson, Ananya Gupta, Shabaana A Khader, and et al

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Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease, Julie Gonneaud, Brian A. Gordon, Carlos Cruchaga, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Susan Brandon, Virginia Buckles, Tamara Donahue, Anne Fagan, Gigi Flynn, Erin Franklin, Cortaiga Gant, Julia Gray, Alexander Groves, Jason Hassenstab, Laura Hoechst-Swisher, David Holtzman, Russ Hornbeck, Gina Jerome, Celeste Karch, Denise Maue-Dreyfus, Eric McDade, Joanne Norton, Richard Perrin, Marc Raichle, Wendy Sigurdson, Peter Wang, Chengjie Xiong, Xiong Xu, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, and et al

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Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson-Gilford Progeria, Alvaro González-Dominguez, Raúl Montañez, Beatriz Castejón-Vega, Jéssica Nuñez-Vasco, Débora Lendines-Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro-Pando, Elísabet Alcocer-Gómez, and Mario D Cordero

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Response to ibudilast treatment according to progressive multiple sclerosis disease phenotype, Andrew D Goodman, Janel K Fedler, Jon Yankey, Elizabeth A Klingner, Dixie J Ecklund, Christopher V Goebel, Robert A Bermel, Marianne Chase, Christopher S Coffey, Eric C Klawiter, Robert T Naismith, Robert J Fox, and SPRINT-MS Investigators

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Efficacy and safety of avapritinib in advanced systemic mastocytosis: Interim analysis of the phase 2 PATHFINDER trial, Jason Gotlib, Andreas Reiter, Stephen T Oh, and et al

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Real-world outcomes of patients with locally advanced or metastatic epithelioid sarcoma, Mrinal M Gounder, Brian A Van Tine, and et al.

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Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer, Xuxu Gou, Shunqiang Li, and et al.

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Activated microglia mitigate Aβ-associated tau seeding and spreading, Maud Gratuze, Yun Chen, Samira Parhizkar, Nimansha Jain, Michael R. Strickland, Javier Remolina Serrano, Marco Colonna, Jason D. Ulrich, and David M. Holtzman

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The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity, Anny Gravdal, Xunjun Xiao, Miriam Cnop, Khadija El Jellas, Stefan Johansson, Pål R. Njølstad, Mark E. Lowe, Bente B. Johansson, Anders Molven, and Karianne Fjeld

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Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition, Allison J. Greaney, Paul W. Rothlauf, Zhuoming Liu, Sean P. J. Whelan, and et al.

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Familial history of autoimmune disorders among patients with pediatric multiple sclerosis, Benjamin M. Greenberg, Soe S. Mar, Shannon Liang, Manu Goyal, and et al

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Electronic clinical decision support for children with minor head trauma and intracranial injuries: A sociotechnical analysis, Jacob K Greenberg, Ayodamola Otun, Azzah Nasraddin, Ross C Brownson, Nathan Kuppermann, David D Limbrick, Po-Yin Yen, and Randi E Foraker

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Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine, Michael J. Greenberg and Jil C. Tardiff

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The role of MRI-guided radiation therapy for palliation of mobile abdominal cancers: A report of two cases, Olga L Green, Lauren E Henke, Alex Price, Areti Marko, Erin J Wittland, Soumon Rudra, Hyun Kim, Sasa Mutic, Jeff Michalski, and Clifford G Robinson

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Lesion Quantification Toolkit: A MATLAB software tool for estimating grey matter damage and white matter disconnections in patients with focal brain lesions, Joseph C Griffis, Nicholas V Metcalf, Maurizio Corbetta, and Gordon L Shulman

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Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: A report from the COVID-19 and Cancer Consortium, P Grivas, K E Stockerl-Goldstein, A Y Zhou, and et al.

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Stages of Objective Memory Impairment predict Alzheimer's disease neuropathology: Comparison with the Clinical Dementia Rating Scale-sum of boxes, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, and Richard B Lipton

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The free and cued selective reminding test predicts Braak stage, Ellen Grober, Qi Qi, Lynn Kuo, Jason Hassenstab, Richard J Perrin, and Richard B Lipton

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Initial experience with single-port robot-assisted radical cystectomy: Comparison of perioperative outcomes between single-port and conventional multiport approaches, James T. Gross, Joel M. Vetter, Kenneth G. Sands, Joshua K. Palka, Sam B. Bhayani, Robert S. Figenshau, and Eric H. Kim

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Clustering of patients with overactive bladder syndrome, James Gross, Joel M Vetter, and H Henry Lai

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Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation, Ya Guan, Hong Niu, Zhongting Liu, Yu Dang, Jie Shen, Mohamed Zayed, Liang Ma, and Jianjun Guan

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Closed-loop acoustic stimulation during sedation with dexmedetomidine (CLASS-D): Protocol for a within-subject, crossover, controlled, interventional trial with healthy volunteers, Christian S Guay, Alyssa K Labonte, Michael C Montana, Eric C Landsness, Brendan P Lucey, MohammadMehdi Kafashan, Simon Haroutounian, Michael S Avidan, Emery N Brown, and Ben Julian A Palanca

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Perlecan in pericellular mechanosensory cell-matrix communication, extracellular matrix stabilisation and mechanoregulation of load-bearing connective tissues, Farshid Guilak, Anthony J Hayes, and James Melrose

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Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis, J.J. Guinan Jr., S.M. Lefler, C.A. Buchman, S.S. Goodman, and J.T. Lichtenhan

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Predicting mortality among patients with liver cirrhosis in electronic health records with machine learning, Aixia Guo, Nikhilesh R. Mazumder, Daniela P. Ladner, and Randi E. Foraker

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Application of a time-series deep learning model to predict cardiac dysrhythmias in electronic health records, Aixia Guo, Sakima Smith, Yosef M. Khan, James R. Langabeer II, and Randi E. Foraker

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Women and ethnoracial minorities with poor cardiovascular health measures associated with a higher risk of developing mood disorder, Aixia Guo, Kari A Stephens, Yosef M Khan, James R Langabeer, and Randi E Foraker

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Enabling qualitative research data sharing using a natural language processing pipeline for deidentification: Moving beyond HIPAA Safe Harbor identifiers, Aditi Gupta, Albert Lai, Jessica Mozersky, Xiaoteng Ma, Heidi Walsh, and James M DuBois

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Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis, Jenny K. Gustafsson, Jazmyne E. Davis, Tracy Rappai, Keely G. McDonald, Devesha H. Kulkarni, Kathryn A. Knoop, Simon P. Hogan, James A.J. Fitzpatrick, Wayne I. Lencer, and Rodney D. Newberry

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SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike, Jenna J Guthmiller, Ya-Nan Dai, Christopher A Nelson, Paige D Hall, Daved H Fremont, and et al

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Evaluation of kratom opioid derivatives as potential treatment option for alcohol use disorder, Anna M Gutridge, Soumen Chakraborty, Balazs R Varga, Elizabeth S Rhoda, Alexander R French, Arryn T Blaine, Quinten H Royer, Haoyue Cui, Jinling Yuan, Robert J Cassell, Márk Szabó, Susruta Majumdar, and Richard M van Rijn

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The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment, Melissa A Haendel, Philip R O Payne, and et al.

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Inpatient versus outpatient intravenous diuresis for the acute exacerbation of chronic heart failure, Ilia G Halatchev, Wen-Chin Wu, Paul A Heidenreich, Elma Djukic, Sumitra Balasubramanian, Kelly B Ohlms, and Jay R McDonald

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Multi-omic analysis elucidates the genetic basis of hydrocephalus, Andrew T Hale, Lisa Bastarache, Diego M Morales, John C Wellons III, David D Limbrick Jr., and Eric R Gamazon

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Thousands of high‑quality sequencing samples fail to show meaningful correlation between 5S and 45S ribosomal DNA arrays in humans, Ashley N. Hall, Tychele N. Turner, and Christine Queitsch

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Quantitative proteomic analysis of diabetes mellitus in heart failure with preserved ejection fraction, Thomas C Hanff, Ali Javaheri, and et al

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Polyclonal epitope mapping reveals temporal dynamics and diversity of human antibody responses to H5N1 vaccination, Julianna Han, Aaron J Schmitz, Sara T Richey, Ya-Nan Dai, Hannah L Turner, Bassem M Mohammed, Daved H Fremont, Ali H Ellebedy, and Andrew B Ward

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A phase 1 study evaluating rovalpituzumab tesirine in frontline treatment of patients with extensive-stage SCLC, Christine L. Hann, Timothy F. Burns, Afshin Dowlati, Daniel Morgensztern, Patrick J. Ward, Martina M. Koch, Chris Chen, Carrianne Ludwig, Maulik Patel, Halla Nimeiri, Philip Komarnitsky, and D. Ross Camidge

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Breast cancer mortality hot spots among Black women with de novo metastatic breast cancer, Yunan Han, Marvin Langston, Lindsay Fuzzell, Saira Khan, Marquita W. Lewis-Thames, Graham A. Colditz, and Justin Xavier Moore

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Societal issues and policy implications related to the use of cannabinoids, cannabis, and cannabis-based medicines for pain management, Simon Haroutounian, Ian Gilron, Joletta Belton, Louisa Degenhardt, Marta Di Forti, David P. Finn, Alexandra Fogarty, Eija Kalso, Elliot Krane, R. Andrew Moore, Michael Rowbotham, Mark Wallace, and Andrew S.C. Rice

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Active surveillance of metastatic renal cell carcinoma: Results from a prospective observational study (MaRCC), Michael R Harrison, Russell K Pachynski, and et al.

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Cost burden of post-transplant lymphoproliferative disease following kidney transplants in Medicare-eligible patients by survival status, Allyson Hart, Yoon Son Ahn, Crystal Watson, Melissa Skeans, Arie Barlev, Bryn Thompson, and Vikas R Dharnidharka

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A timely call to arms: COVID-19, the circadian clock, and critical care, Jeffrey Haspel, Minjee Kim, Phyllis Zee, Tanja Schwarzmeier, Sara Montagnese, Satchidananda Panda, Adriana Albani, and Martha Merrow

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A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques, Ahmed O Hassan, Friederike Feldmann, Haiyan Zhao, David T Curiel, Atsushi Okumura, Tsing-Lee Tang-Huau, James Brett Case, Kimberly Meade-White, Julie Callison, Rita E Chen, Jamie Lovaglio, Patrick W Hanley, Dana P Scott, Daved H Fremont, Heinz Feldmann, and Michael S Diamond

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An intranasal vaccine durably protects against SARS-CoV-2 variants in mice, Ahmed O Hassan, Swathi Shrihari, Matthew J Gorman, Baoling Ying, Dansu Yaun, Saravanan Raju, Rita E Chen, Igor P Dmitriev, Elena Kashentseva, Lucas J Adams, Colin Mann, Meredith E Davis-Gardner, Mehul S Suthar, Pei-Yong Shi, Erica Ollmann Saphire, Daved H Fremont, David T Curiel, Galit Alter, and Michael S Diamond

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Ablative five-fraction stereotactic body radiation therapy for inoperable pancreatic cancer using online MR-guided adaptation, Comron Hassanzadeh, Soumon Rudra, Ani Bommireddy, William G Hawkins, Andrea Wang-Gillam, Ryan C Fields, Bin Cai, Justin Park, Olga Green, Michael Roach, Lauren Henke, and Hyun Kim

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Is comprehensiveness critical? Comparing short and long format cognitive assessments in preclinical Alzheimer disease, Jason Hassenstab, Jessica Nicosia, Megan LaRose, Andrew J Aschenbrenner, Brian A Gordon, Tammie L S Benzinger, Chengjie Xiong, and John C Morris

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Genetic liability to cannabis use disorder and COVID-19 hospitalization, Alexander S Hatoum, Claire L Morrison, Sarah M C Colbert, Evan A Winiger, Emma C Johnson, Arpana Agrawal, and Ryan Bogdan

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Consensus recommendations on the treatment of opioid use disorder in the emergency department, Kathryn Hawk, Jason Hoppe, Eric Ketcham, Alexis LaPietra, Aimee Moulin, Lewis Nelson, Evan Schwarz, Sam Shahid, Donald Stader, Michael P Wilson, and Gail D'Onofrio

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Survival predictors of heart rate variability after myocardial infarction with and without low left ventricular ejection fraction, Junichiro Hayano, Norihiro Ueda, Masaya Kisohara, Emi Yuda, Robert M Carney, and James A Blumenthal

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Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation, and block of autophagy, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Frankie Chiu, Francoise Coustry, and Karen L Posey

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Analysis of delayed surgical treatment and oncologic outcomes in clinical stage I non-small cell lung cancer, Brendan T. Heiden, Daniel B. Eaton, Kathryn E. Engelhardt, Su-Hsin Chang, Yan Yan, Mayank R. Patel, Daniel Kreisel, Ruben G. Nava, Bryan F. Meyers, Benjamin D. Kozower, and Varun Puri

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Identifying risk factors and patterns for early recurrence of pancreatic neuroendocrine tumors: A multi-institutional study, Charlotte M Heidsma, Ryan Fields, Bradley A Krasnick, and et al

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Academic performance of children with sickle cell disease in the United States: A meta-analysis, Andrew M Heitzer, Latacha Hamilton, Claire Stafford, Jeffrey Gossett, Lara Ouellette, Ana Trpchevska, Allison A King, Guolian Kang, and Jane S Hankins