Submissions from 2012
Educating medical students in musculoskeletal surgery and medicine: How to get a course up and running at your institution: AOA Critical Issues, Charles S. Day, Joseph Bernstein, and Martin I. Boyer
MuSiC: Identifying mutational significance in cancer genomes, Nathan D. Dees, Qunyuan Zhang, Cyriac Kandoth, Michael C. Wendl, William Schierding, Daniel C. Kobolt, Thomas B. Mooney, Matthew B. Callaway, David Dooling, Elaine R. Mardis, Richard K. Wilson, and Li Ding
Recent progress in West Nile virus diagnosis and vaccination, Marina De Filette, Sebastian Ulbert, Mike Diamond, and Niek N. Sanders
Social cognition in Williams syndrome: Relations between performance on the social attribution task and cognitive and behavioral characteristics, Faye van der Fluit, Michael S. Gaffrey, and Bonita P. Klein-Tasman
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis, John F. DiPersio and et al
Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer’s disease, Krikor Dirkranian, Jungsu Kim, Floy R. Stewart, Marilyn A. Levy, and David M. Holtzman
Guidelines for the use and interpretation of assays for monitoring autophagy, Abhinav Diwan, Seungmin Hwang, Indira Mysorekar, William A. Weiss, and et al
Mouse transgenesis in a single locus with independent regulation for multiple fluorophores, Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, and Nathaniel Heintz
Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells, Barbara Drobits, Martin Holcmann, Nicole Amberg, Melissa Swiecki, Roland Grundtner, Martina Hammer, Marco Colonna, and Maria Sibilia
Implementing automated surveillance for tracking Clostridium difficile infection at multiple healthcare facilities, Erik R. Dubberke, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Kurt B. Stevenson, Julie E. Mangino, Yosef M. Khan, Victoria J. Fraser, and Centers for Disease Control and Prevention Epicenter Program
Accuracy of fall prediction in Parkinson disease: six-month and 12-month prospective analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, and Gammon M. Earhart
Whole-genome sequencing to identify mutants and polymorphisms in Chlamydomonas reinhardtii, Susan K. Dutcher, Linya Li, Huawen Lin, Leslie Meyer, Thomas H. Giddings Jr., Alan L. Kwan, and Brian L. Lewis
AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia, Arucha L. Ekeowa-Anderson, Karin J. Purdie, Karen Gibbon, Carolyn R. Byrne, Jeffrey M. Arbeit, Catherine A. Harwood, and Ryan F. L. O'Shaughnessy
Nature and function of insulator protein binding sites in the Drosophila genome, Sarah C. R. Elgin and et al
PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers, Matthew J. Ellis and et al
Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a, Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, and Dong Yu
Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis, Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, and Ganes C. Sen
Interethnic differences in β-2 agonist treatment of acute asthma on electrolyte/glucose concentrations, Ian Ferguson, Kazuko Matsuda, Stacey House, John Schneider, Kristen Aubuchon, and Lawrence Lewis
Comparison of accelerated partial breast irradiation via multicatheter interstitial brachytherapy versus whole breast radiation, Daniel J. Ferraro, Adam A. Garsa, Todd A. DeWees, Julie A. Margenthaler, Michael Naughton, Rebecca Aft, William E. Gillanders, Timothy Eberlein, Melissa A. Matesa, and Imran Zoberi
A multicenter evaluation of diagnostic tools to define endpoints for programs to eliminate bancroftian filariasis, Peter U. Fischer, Ramakrishna U. Rao, and et al
The structure of the PapD-PapGII pilin complex reveals an open and flexible p5 pocket, Bradley Ford, Denis Verger, Karen Dodson, Ender Volkan, Maria Kostakioti, Jennifer Elam, Jerome Pinkner, Gabriel Waksman, and Scott Hultgren
Administration of QTc prolonging medications in emergency department patients with prolonged QTc, Lucy Franjic, Stacey House, Irena Vitkovitsky, and S. Eliza Halcomb
QTc prolongation is associated with hypokalemia and hypocalcemia in emergency department patients, Lucy Franjic, Stacey House, Irena Vitkovitsky, and S. Eliza Halcomb
Reply to Herigon and Newland, Stephanie A. Fritz, Bernard C. Camins, Jonathan Dukes, and Gregory A. Storch
Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report, Ryan K. Funk, Daniel J. Ferraro, Richard J. Perrin, Kyle M. Hurth, John J. Stephens, David B. Mansur, Michael R. Chicoine, Joseph R. Simpson, and Jerry J. Jaboin
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104), Thomas F. Gajewski, April KS Salama, Donna Niedzwiecki, Jeffrey Johnson, Gerald Linette, Cynthia Bucher, Michelle A. Blaskovich, Said M. Sebti, Frank Haluska, and Cancer and Leukemia Group B
The effect of changes in intraocular pressure on the risk of primary open-angle glaucoma in patients with ocular hypertension: An application of latent class analysis, Feng Gao, J. P. Miller, Stefano Miglior, Julia A. Beiser, Valter Torri, Michael A. Kass, and Mae E. Gordon
Genome-wide association and functional follow-up reveals new loci for kidney function, Xiaoyi Gao, Mary Feitosa, Michael Province, Shamika Ketkar, Ingrid Borecki, and et al.
Partner randomized controlled trial: Study protocol and coaching intervention, Jane M. Garbutt, Gabrielle Highstein, Yan Yan, and Robert C. Strunk
A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans, Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, and Jennifer K. Lodge
Snail promotes the cell-autonomous generation of Flk1 + endothelial cells through the repression of the microRNA-200 family, Jennider G. Gill, Ellen M. Langer, R Coleman Lindsley, Mi Cai, Theresa L. Murphy, and Kenneth M. Murphy
Isolated short femur length on second-trimester sonography: A marker for fetal growth restriction and other adverse perinatal outcomes, Katherine R. Goetzinger, Alison G. Cahill, George A. Macones, and Anthony O. Odibo
Quantitative assessment of participant knowledge and evaluation of participant satisfaction in the CARES training program, Melody S. Goodman, Xuemei Si, Jewel D. Stafford, Adesuwa Obasohan, and Cheryl Mchunguzi
Quantitative assessment of participant knowledge and evaluation of participant satisfaction in the CARES training program, Melody S. Goodman, Xuemei Si, Jewel D. Stafford, Adesuwa Obasohan, and Cheryl Mchunguzi
Analysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during development, Jennifer Govero, Balraj Doray, Hongdong Bai, and Stuart Kornfeld
RIM promotes calcium channel accumulation at active zones of the Drosophila neuromuscular junction, Ethan R. Graf, Vera Valakh, Christina M. Wright, Chunlai Wu, Zhihua Liu, Yong Q. Zhang, and Aaron DiAntonio
I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity, Daniel Granados-Fuentes, Aaron J. Norris, Yarimar Carrasquillo, Jeanne M. Nerbonne, and Erik D. Herzog
Attempted endoscopic closure of a pancreaticocolonic fistula with an over-the-scope clip, Darrell M. Gray II and Daniel K. Mullady
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice, Pascale S. Guiton, Corinne K. Cusumano, Kimberly A. Kline, Karen W. Dodson, Zhenfu Han, James W. Janetka, Jeffrey P. Henderson, Michael G. Caparon, and Scott J. Hultgren
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors, Maria Hadjifrangiskou, Alice P. Gu, Jerome S. Pinkner, Maria Kostakioti, Ellisa W. Zhang, Sarah E. Greene, and Scott J. Hultgren
What does it take to stick around?: Molecular insights into biofilm formation by uropathogenic Escherichia coli, Maria Hadjifrangiskou and Scott J. Hultgren
Prevention of musculoskeletal disorders in workers: Classification and health surveillance – statements of the Scientific Committee on Musculoskeletal Disorders of the International Commission on Occupational Health, Mats Hagberg, Francesco Saverio Violante, Roberta Bonfiglioli, Alexis Descatha, Judith Gold, Brad Evanoff, and Judith K. Sluiter
Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates, Marc R. Hammerman
Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways, Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, and Alison M. Goate
Intermediate outcomes following percutaneous fixation of proximal humeral fractures, Alicia K. Harrison, Konrad I. Gruson, Benjamin Zmistowski, Jay Keener, Leesa Galatz, Gerald Williams, Bradford O. Parsons, and Evan L. Flatgow
Role of the polarity protein Scribble for podocyte differentiation and maintenance, Bjorn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H. Miner, Gerd Walz, and Tobias B. Huber
Leishmania RNA virus: When the host pays the toll, Mary-Anne Hartley, Catherine Ronet, Haroun Zangger, Stephen M. Beverley, and Nicolas Fasel
Apolipoprotein e, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide, Tadafumi Hashimoto, Alberto Serrano-Pozo, Yukiko Hori, Kenneth W. Adams, Shuko Takeda, Adrian Olaf Banerji, Akinori Mitani, Daniel Joyer, Diana H. Thyssen, Brian J. Bacskai, Matthew P. Frosch, Tara L. Spires-Jones, Mary Beth Finn, David M. Holtzman, and Bradley T. Hyman
Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, and Japanese Alzheimer's Disease Neuroimaging Initiative
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales, A. C. Heath, P. A. F. Madden, and et al
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA, Andrew C. Heath, Pamela A. F. Madden, and et al
Early brain vulnerability in Wolfram syndrome, Tamara Hershey, Heather M. Lugar, Joshua S. Shimony, Jerrel Rutlin, Jonathan M. Koller, Dana C. Perantie, Alex R. Paciorkowski, Sarah A. Eisenstein, M. Alan Permutt, and Washington University Wolfram Study Group
Validation of self-reported measures in health disparities research, Bertha Hidalgo and Melody Goodman
Fibroblast growth factor 2 affects vascular remodeling after acute myocardial infarction, Stacey House, Thomas Belanger, Carla Weinheimer, and David Ornitz
Endothelial-specific fibroblast growth factor receptor 1 and 2 deletion impairs vascular remodeling and recovery in an in vivo, closed-chest model of cardiac ischemia-reperfusion injury, Stacey House, Carla Weinheimer, Attila Kovacs, and David Ornitz
Fibroblast growth factor receptor signaling in endothelium mediates post-ischemic vascular remodeling and functional recovery in an in vivo, closed-chest model of acute myocardial infarction, Stacey House, Carla Weinheimer, Attila Kovacs, and David Ornitz
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, and Edward J. Pearce
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal, Sung-Ho Huh, Jennifer Jones, Mark E. Warchol, and David M. Ornitz
Clinical application of heart rate variability after acute myocardial infarction, Heikki V. Huikuri and Phyllis K. Stein
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis, Michelle A. Hurchla and Katherine N. Weilbaecher
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, and Brenda L. Fredericksen
Adjuvant chemotherapy for breast cancer in patients with schizophrenia, Mark Hwang, Mishel Farasatpour, Campbell D. Williams, Julie A. Margenthaler, Katherine S. Virgo, and Frank E. Johnson
Fast, sensitive discovery of conserved genome-wide motifs, NNamdi E. Ihuegbu, Gary D. Stormo, and Jeremy Buhler
A survey tool for measuring evidence-based decision making capacity in public health agencies, Julie A. Jacobs, Paula F. Clayton, Cassandra Dove, Tanya Funchess, Ellen Jones, Ghazala Perveen, Brandon Skidmore, Victor Sutton, Sarah Worthington, Elizabeth A. Baker, Anjali D. Deshpande, and Ross C. Brownson
Tools for implementing an evidence-based approach in public health practice, Julie A. Jacobs, Ellen Jones, Barbara A. Gabella, Bonnie Spring, and Ross C. Brownson
GSK-3β: A bifunctional role in cell death pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, and Dinesh Thotala
Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer’s disease Ibero-American cohort, Sheng C. Jin, Pau Pastor, Breanna Cooper, Sebastian Cervantes, Bruno A. Benitez, Cristina Razquin, Alison Goate, Ibero-American Alzheimer Disease Genetics Group Researchers, and Carlos Cruchaga
Antegrade endoscopic removal of retained urethral sling mesh in the bladder, Michael H. Johnson, Genoa G. Ferguson, and Carl G. Klutke
It's all in the lens: Differences in views on obesity prevention between advocates and policy makers, Ellen Jones, Amy A. Eyler, Leah Nguyen, Jooyoung Kong, Ross C. Brownson, and Jessica H. Bailey
Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy, Pierre-Emmanuel Joubert, Scott Werneke, Claire de la Calle, Florence Guivel-Benhassine, Alessandra Giodini, Lucie Peduto, Beth Levine, Olivier Schwartz, Deborah Lenschow, and Matthew L. Albert
Hospital-onset clostridium difficile infection rates in persons with cancer or Hematopoietic stem cell transplant: A C3IC network report, Mini Kamboj, Crystal Son, Sherry Cantu, Roy R. Chemaly, Jeanne Dickman, Erik Dubberke, Lisa Engles, Theresa Lafferty, Gale Liddell, Mary Ellen Lesperance, Julie E. Mangino, Stacy Martin, Jennie Mayfield, Sapna A. Mehta, Susan O'Rourke, Cheryl S. Perego, Randy Taplitz, Janet A. Eagan, and Kent A. Sepkowitz
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, and Judith L. Campbell
Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains, Celeste M. Karch, Amanda T. Jeng, Petra Nowotny, Janet Cady, Carlos Cruchaga, and Alison M. Goate
Heart rate variability changes at 2400 m altitude predicts acute mountain sickness on further ascent at 3000–4300 m altitudes, Heikki M. Karinen, Arja Uusitalo, Henri Vaha-Ypya, Mika Kahonen, Juha E. Peltonen, Phyllis K. Stein, Jari Viik, and Heikki O. Tikkanen
A multicenter study of Clostridium difficile infection-related colectomy, 2000-2006, Amelia M. Kasper, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Julie E. Mangino, Yosef M. Khan, Bala Hota, Victoria J. Fraser, and Erik R. Dubberke
Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner, Aparna Kaul, Yi-Hsien Chen, Ryan J. Emnett, Sonika Dahiya, and David H. Gutmann
Effect of inhaled glucocorticoids in childhood on adult height, H. William Kelly, Alice L. Sternberg, Rachel Lescher, Anne L. Fuhlbrigge, Paul Williams, Robert S. Zeiger, Hengameh H. Raissy, Mark L. Van Natta, James Tonascia, and Robert C. Strunk
Year in review 2011: Critical Care – neurocritical care, Salah G. Keyrouz and Michael N. Diringer
Ewing's sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review, Waseem Khaliq, Mohammad Farshad Bahador, Thomas Nichols Laurence, Ronald Andrew Sapiente, James Sheridan Lewis Jr., and David Lee Graham
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration, Shyam B. Khatau, Ryan J. Bloom, Saumendra Bajpai, David Razafsky, Shu Zhang, Anjil Giri, Pei-Hsun Wu, Jorge Marchand, Alfredo Celedon, Christopher M. Hale, Sean X. Sun, Didier Hodzic, and Denis Wirtz
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing, Dong-Hwee Kim, Shyam B. Khatau, Yunfeng Feng, Sam Walcott, Sean X. Sun, Gregory D. Longmore, and Denis Wirtz
Off-clamp robot-assisted partial nephrectomy for complex renal tumors, Eric H. Kim, Youssef S. Tanagho, Gurdarshan Sandhu, Sam B. Bhayani, and R. Sherburne Figenshau
A noncomplementation screen for quantitative trait alleles in Saccharomyces cerevisiae, Hyun Seok Kim, Juyoung Huh, Linda Riles, Alejandro Reyes, and Justin C. Fay
A role for the membrane Golgi protein Ema in autophagy, Sungsu Kim and Aaron DiAntonio
Functional consequences of cell type-restricted expression of laminin alpha-5 in mouse placental labyrinth and kidney glomerular capillaries, Sung Tae Kim, Tracy L. Adair-Kirk, Robert M. Senior, and Jefrey H. Miner
Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA, Kathryn A. Knoop and Rodney D. Newberry
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing, Daniel C. Koboldt, Qunyuan Zhang, David E. Larson, Dong Shen, Michael D. McLellan, Ling Lin, Christopher A. Miller, Elaine R. Mardis, Li Ding, and Richard K. Wilson
A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilatorassociated pneumonia, Marin H. Kollef, Jean Chastre, Marc Clavel, Marcos I. Restrepo, Bart Michiels, Kone Kaniga, Iolanda Cirillo, Holly Kimko, and Rebecca Redman
Economic impact of ventilator-associated pneumonia in a large matched cohort, Marin H. Kollef, Cindy W. Hamilton, and Frank R. Ernst
Ubiquitination and degradation of the hominoid- specific oncoprotein TBC1D3 Is mediated by CUL7 E3 ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, and Philip D. Stahl
Challenging presentations of cavernous sinus thrombophlebitis, Courtney L. Kraus and Susan M. Culican
Small media and client reminders for colorectal cancer screening: Current use and gap areas in CDC's colorectal cancer control program, Matthew W. Kreuter, Lori B. Garibay, Debbie J. Pfeiffer, Jennifer C. Morgan, Melonie Thomas, Katherine M. Wilson, Jennifer Pieters, Kellie Szczepaniec, Amy Scott, and Timothy J. Poor
Polygenic threshold model with sex dimorphism in adolescent idiopathic scoliosis: The Carter effect, Lisa M. Kruse, Jillian G. Buchan, Christina A. Gurnett, and Matthew B. Dobbs
Rehabilitation after anterior cruciate ligament reconstruction: A systematic review, L. M. Kruse, B. Gray, and R. W. Wright
The L.E.A.D. framework: Using tools from evidence-based public health to address evidence needs for obesity prevention, Shiriki Kumanyika, Ross C. Brownson, and Allen Cheadle
Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma, Rachel L. Kyllo, Youssef S. Tanagho, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Shahab P. Hillyer, Shyam S. Sukumar, Kenneth G. Nepple, and Sam B. Bhayani
Observational Research in Childhood Infectious Diseases (ORChID): A dynamic birth cohort study, Stephen Bernard Lambert, Robert S. Ware, Anne L. Cook, Frances A. Maguire, David M. Whiley, Seweryn Bialasiewicz, Ian M. Mackay, David Wang, Theo P. Sloots, Michael D. Nissen, and Keith Grimwood
Paragonimus kellicotti Fluke infections in Missouri, USA, Michael A. Lane, Mary C. Barsanti, Carlos A. Santos, Michael Yeung, Sam J. Lubner, and Gary J. Weil
Beyond 30 days: Does limiting the duration of surgical site infection follow-up limit detection?, Julie D. Lankiewicz, Deborah S. Yokoe, Margaret A. Olsen, Fallon Onufrak, Victoria J. Fraser, Kurt Stevenson, Yosef Khan, David Hooper, Richard Platt, and Susan S. Huang
AHR and the transcriptional regulation of Type-17/22 ILC, Jacob S. Lee, Marina Cella, and Marco Colonna
