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Submissions from 2007

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The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees, E Warwick Daw and Robert Yu

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Frequent gain and loss of functional transcription factor binding sites, Scott W. Doniger and Justin C. Fay

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The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site, Balraj Doray, Intaek Lee, Jane Knisely, Guojun Bu, and Stuart Kornfeld

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Severity of Clostridium difficile-associated disease (CDAD) in allogeneic stem cell transplant recipients: Evaluation of a CDAD severity grading system, Erik R. Dubberke, Justin Sadhu, Robert Gatti, Kimberly A. Reske, John F. DiPersio, Steven M. Devine, and Victoria J. Fraser

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Clustering of eating disorder symptoms in a general population female twin sample: A latent class analysis, Alexis E. Duncan, Kathleen K. Bucholz, Rosalind J. Neuman, Arpana Agrawal, Pamela A F Madden, and Andrew C. Heath

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Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines, Axel A. Elling, Makedonka Mitreva, Justin Recknor, Xiaowu Gai, John Martin, Thomas R. Maier, Jeffrey P. McDermott, Tarek Hewezi, David McK Bird, Eric L. Davis, Richard S. Hussey, Dan Nettleton, James P. McCarter, and Thomas J. Baum

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The effect of compliance on the impact of mass drug administration for elimination of lymphatic filariasis in Egypt, Maged El Setouhy, Khaled M. Abd Elaziz, Hanan Helmy, Hoda A. Farid, Hussein A. Kamal, Reda M.R. Ramzy, William D. Shannon, and Gary J. Weil

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Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains, Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, and Colin G. Nichols

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A critical appraisal of molecular xenomonitoring as a tool for assessing progress toward elimination of lymphatic filariasis, Hoda A. Farid, Zakariya S. Morsy, Hanan Helmy, Reda M.R. Ramzy, Maged El Setouhy, and Gary J. Weil

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Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial, Thomas Ferkol and et al

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Persistence of Brugia malayi DNA in vector and non-vector mosquitoes: Implications for xenomonitoring and transmission monitoring of lymphatic filariasis, Peter Fischer, Sara M. Erickson, Kerstin Fischer, Jeremy F. Fuchs, Ramakrishna U. Rao, Bruce M. Christensen, and Gary J. Weil

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Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients, Elizabeth Foglia, Mary Dawn Meier, and Alexis Elward

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Impaired mononuclear cell immune function in extreme obesity is corrected by weight loss, Luigi Fontana, J. Christopher Eagon, Marco Colonna, and Samuel Klein

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Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk, Luigi Fontana, Timothy E. Meyer, Samuel Klein, and John O. Holloszy

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Genetics of body mass stability and risk for chronic disease: A 28-year longitudinal study, Carol E. Franz, MIchael D. Grant, Kristen C. Jacobson, William S. Kremen, Seth A. Eisen, Hong Xian, James Romeis, Heather Thompson-Brenner, and Michael J. Lyons

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ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity, Rodrigo A. Fuentealba, Maria Ines Barría, Jiyeon Lee, Judy Cam, Claudia Araya, Claudia A. Escudero, Nibaldo C. Inestrosa, Francisca C. Bronfman, Guojun Bu, and Maria-Paz Marzolo

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Common genetic risk of major depression and nicotine dependence: The contribution of antisocial traits in a United States veteran male twin cohort, Qiang Fu, Andrew C. Heath, Kathleen K. Bucholz, Michael J. Lyons, Ming T. Tsuang, William R. true, and Seth A. Eisen

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Toxoplasma gondii strains defective in oral transmission are also defective in developmental stage differentiation, Blima Fux, Julie Nawas, Asis Khan, Darcy B. Gill, Chunlei Su, and L David Sibley

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Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation, Corinne K. Garofalo, Thomas M. Hooton, Steven M. Martin, Walter E. Stamm, Joseph J. Palermo, Jeffrey I. Gordon, and Scott J. Hultgren

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Identification of a novel polyomavirus from patients with acute respiratory tract infections, Anne M. Gaynor, Michael D. Nissen, David M. Whiley, Ian M. Mackay, Stephen B. Lambert, Guang Wu, Daniel C. Brennan, Gregory A. Storch, Theo P. Sloots, and David Wang

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Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults, Barbara Geller, Rebecca Tillman, and Kristine Bolhofner

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NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat, Antonino Germanò, Mariella Caffo, Filippo Flavio Angileri, Francesca Arcadi, Jennifer Newcomb, Gerardo Caruso, Francesco Meli, Jose A. Pineda, Stephen B. Lewis, Kevin K. W. Wang, Placido Bramanti, Chiara Costa, and Ronald L. Hayes

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Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse, Emanuele Giurisato, Marina Cella, Toshiyuki Takai, Tomohiro Kurosaki, Yungfeng Feng, Gegory D. Longmore, Marco Colonna, and Andrey S. Shaw

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Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report, Priya K. Gopalan, John C. Clohisy, Amanda F. Cashen, and Charles S. Eby

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Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice, Daniel B. Graham, Charles M. Robertson, Jhoanne Bautista, Francesca Mascarenhas, M. Julia Diacovo, Vivianne Montgrain, Siu Kit Lam, Viviana Cremasco, W. Michael Dunne, Roberta Faccio, Craig M. Coopersmith, and Wojciech Swat

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An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells, Daniel B. Graham, Linda M. Stephenson, Siu Kit Lam, Karry Brim, Hyang Mi Lee, Jhoanne Bautista, Susan Gilfillan, Shreeram Akilesh, Keiko Fujikawa, and Wojciech Swat

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A high-resolution map of segmental DNA copy number variation in the mouse genome, Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, William D. Shannon, Xia Li, Howard L. McLeod, James M. Cheverud, and Timothy J. Ley

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Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome, Tina Graves, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, and et al

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Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia, Mitchell H. Grayson, Dorothy Cheung, Michelle M. Rohlfing, Robert Kitchens, Daniel E. Spiegel, Jennifer Tucker, John T. Battaile, Yael Alevy, Le Yan, Eugene Agapov, Edy Y. Kim, and Michael J. Holtzman

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Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome, Jason S. Groshong, Melissa J. Spencer, Bula J. Bhattacharyya, Elena Kudryashova, Bhupinder P.S. Vohra, Roberto Zayas, Robert L. Wollmann, Richard J. Miller, and Christopher M. Gomez

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Stable preanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck, Brian K. Haarer, Astrid Hoes Helfant, Scott A. Nelson, John A. Cooper, and David C. Amberg

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E2F8 is a nonreceptor activator of heterotrimeric G proteins, Ian S. Hagemann, Kirk D. Narzinski, and Thomas J. Baranski

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Organogenesis of kidney and endocrine pancreas: The window opens, Marc R. Hammerman

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Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D, Kevan L. Hartshorn, Mitchell R. White, Tesfaldet Tecle, Ida Tornoe, Grith L. Sorensen, Erika C. Crouch, and Uffe Holmskov

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Large scale gene expression profiles of regenerating inner ear sensory epithelia, R. D. Hawkins, Stavros Bashiardes, Kara E. Powder, Samin A. Sajan, Veena Bhonagiri, David M. Alvarado, Judith Speck, Mark E. Warchol, and Michael Lovett

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Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B, Coy D. Heldermon, Anne K. Henning, Kevin K. Ohlemiller, Judith M. Ogilvie, Erik D. Herzog, Annalisa Breidenbach, Carole Vogler, David F. Wozniak, and Mark S. Sands

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Comparison of C. elegans and C. briggsae genome sequences reveals extensive conservation of chromosome organization and synteny, LaDeana W. Hiller, Raymond D. Miller, Scott E. Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, and Robert H. Waterston

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Linkage and association analyses of principal components in expression data, Anthony L. Hinrichs, Robert Culverhouse, Carol H. Jin, and Brian K. Suarez

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Haplotyping a quantitative trait with a high-density map in experimental crosses, Wei Hou, John Stephen F. Yap, Song Wu, Tian Liu, James M. Cheverud, and Rongling Wu

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The cis-regulatory logic of the mammalian photoreceptor transcriptional network, Timothy H. Hsiau, Claudiu Diaconu, Connie A. Myers, Jongwoo Lee, Constance L. Cepko, and Joseph C. Corbo

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Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Craig H. Bassing, Tej K. Pandita, and Barry P. Sleckman

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Genetic and pharmacological factors that influence reproductive aging in nematodes, Stacie E. Hughes, Kimberley Evason, Chengjie Xiong, and Kerry Kornfeld

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Gene duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a, Keith A. Hultman, Nathan Bahary, Leonard I. Zon, and Stephen L. Johnson

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The Par-1/MARK family of protein kinases: From polarity to metabolism, Jonathan Hurov and Helen Piwnica-Worms

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Changing human visual field organization from early visual to extra-occipital cortex, Anthony I. Jack, Gaurav H. Patel, Serguei V. Astafiev, Abraham Z. Snyder, Erbil Akbudak, Gordon L. Shulman, and Maurizio Corbetta

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Genomic and gene regulatory signatures of cryptozoic adaptation: Loss of blue sensitive photoreceptors through expansion of long wavelength-opsin expression in the red flour beetle Tribolium castaneum, Magdalena Jackowska, Riyue Bao, Zhenyi Liu, Elizabeth C. McDonald, Tiffany A. Cook, and Markus Friedrich

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Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing, Verena Jantsch, Lois Tang, Pawel Pasierbek, Alexandra Penkner, Sudhir Nayak, Antoine Baudrimont, Tim Schedl, Anton Gartner, and Josef Loidl

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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: Applications in diagnostic imaging and therapy, Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter O. Simon Jr, Peter S. Goedegebuure, Jinbin Xu, Lynne Jones, Katherine Chang, Fabian Johnston, Kathryn Trinkaus, Richard S. Hotchkiss, Robert H. Mach, and William G. Hawkins

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Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae, Thomas E. Kehl-Fie and Joseph W. St. Geme III

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Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice, Jennifer Kelly, Aslam Ali Khan, Jiyi Yin, Thomas A. Ferguson, and Rajendra S. Apte

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Pancreatitis following Olanzapine Therapy: A Report of Three Cases, Thomas A. Kerr, Sreenivasa Jonnalagadda, Chandra Prakash, and Riad Azar

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Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation, Jeong Sook Kim-Han and Karen L. O'Malley

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Rheumatoid arthritis, item response theory, Blom transformation, and mixed models, Aldi T. Kraja, Jon Corbett, An Ping, Rosa S. Lin, Petra A. Jacobsen, Michael Crosswhite, Ingrid B. Borecki, and Michael A. Province

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Circumstances of patient falls and injuries in 9 hospitals in a midwestern healthcare system, Melissa J. Krauss, Sheila L. Nguyen, Wm. Claiborne Dunagan, Stanley Birge, Eileen Costantinou, Shirley Johnson, Barbara Caleca, and Victoria J. Fraser

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Polyamine permeation and rectification of kir4.1 channels, Yuri V. Kucheryavykh, Wade L. Pearson, Harley T. Kurata, Misty J. Eaton, Serguei N. Skatchkov, and Colin G. Nichols

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The role of the cytoplasmic pore in inward rectification of Kir2.1 channels, Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, and Colin G. Nichols

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Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial, Lori M. B. Laffel, William C. Hsu, Janet B. McGill, Luigi Meneghini, and Lisa K. Volkening

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The bandit, a new DNA transposon from a hookworm— possible horizontal genetic transfer between host and parasite, Thewarach Laha, Alex Loukas, Supatra Wattanasatitarpa, Jenjira Somprakhon, Nonglack Kewgrai, Paiboon Sithithaworn, Sasithorn Kaewkes, Makedonka Mitreva, and Paul J. Brindley

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Targeted discovery of novel human exons by comparative genomics, Laura Langton, Michael Stevens, Charles L.G. Comstock, Michael R. Brent, and et al

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The 14-3-3τ phosphoserine-binding protein is required for cardiomyocyte survival, Jeffrey M. C. Lau, Xiaohua Jin, Jie Ren, Joan Avery, Brian J. DeBosch, Ilya Treskov, Traian S. Lupu, Attila Kovacs, Carla Weinheimer, and Anthony J. Muslin

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Yersiniabactin is a virulence factor for Klebsiella pneumoniae during pulmonary infection, Matthew S. Lawlor, Christopher O'Connor, and Virginia L. Miller

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Clostridium difficile in the intensive care unit: Epidemiology, costs, and colonization pressure, Steven J. Lawrence, Laura A. Puzniak, Brooke N. Shadel, Kathleen N. Gillespie, Marin H. Kollef, and Linda M. Mundy

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Comparative analysis of the regulation of rovA from the pathogenic Yersiniae, Matthew B. Lawrenz and Virginia L. Miller

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Evaluation of a novel chromogenic agar medium for isolation and differentiation of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis isolates, Nathan A. Ledeboer, Kingshuk Das, Michael Eveland, Celine Roger-Dalbert, Sandrine Mailler, Sonia Chatellier, and William Michael Dunne

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Prevalence of cervical spine stenosis: Anatomic study in cadavers, Michael J. Lee, Ezequiel H. Cassinelli, and K. Daniel Riew

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A little stress is good: IFN-γ, demyelination, and multiple sclerosis, Jason R. Lees and Anne H. Cross

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Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli, Yvonne M. Lee, Karen W. Dodson, and Scott J. Hultgren

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Management of juvenile idiopathic scoliosis, Lawrence G. Lenke and Matthew B. Dobbs

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Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current, Jingdong Li, Celine Marionneau, Olha Koval, Leonid Zingman, Peter J. Mohler, Jeanne M. Nerbonne, and Mark E. Anderson

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PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer, W. T. Lim, W. H. Zhang, C. R. Miller, J. W. Watters, F. Gao, A. Viswanathan, R Govindan, and H. L. McLeod

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Vascular injury from an arterial closure device, Jeffrey P. C. Lin, Brian G. Rubin, and William D. Middleton

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Large-scale in silico mapping of complex quantitative traits in inbred mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, and Ming You

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Functional association of Sun1 with nuclear pore complexes, Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, and Kyle J. Roux

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Acrochordon-like basal cell carcinomas in patients with basal cell nevus syndrome, David N. Lortscher, Roberta D. Sengelmann, and Shawn B. Allen

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Contribution of invariant residues to the function of Rgg family transcription regulators, Jennifer Loughman and Michael G. Caparon

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Diffusion tensor imaging predicts hyperacute spinal cord injury severity, David N. Loy, Joong Hee Kim, Mingqiang Xie, Robert E. Schmidt, Kathryn Trinkaus, and Sheng-Kwei Song

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Psychotropic prescriptions in a sample including both healthy and mood and disruptive disordered preschoolers: relationships to diagnosis, impairment, prescriber type, and assessment methods, Joan L. Luby, Melissa Meade Stalets, and Andy C. Belden

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Three clinical cases of DSM-IV mania symptoms in preschoolers, Joan Luby, Mini Tandon, and Ginger Nicol

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Ivermectin resistance in Onchocerca volvulus: Toward a genetic basis, Sara Lustigman and James P. McCarter

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Common human cancer genes discovered by integrated gene-expression analysis, Yan Lu, Yijun Yi, Pengyuan Liu, Weidong Wen, Michael James, Daolong Wang, and Ming You

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Psychometric properties of DSM assessments of illicit drug abuse and dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), M. T. Lynskey and A. Agrawal

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Mutations in α-tubulin confer dinitroaniline resistance at a cost to microtubule function, Christopher Ma, Catherine Li, Lakshmi Ganesan, Jean Oak, Susan Tsai, David Sept, and Naomi S. Morrissette

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Clamping the Mec1/ATR checkpoint kinase into action, Jerzy Majka and Peter M.J. Burgers

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Case-control study of surgical site infections associated with pacemakers and implantable cardioverter-defibrillators, Jonas Marschall, Diane Hopkins-Broyles, Marilyn Jones, Victoria J. Fraser, and David K. Warren

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Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: A surveillance study, Jonas Marschall, Carole Leone, Marilyn Jones, Deborah Nihill, Victoria J. Fraser, and David K. Warren

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Regulation of KATP channel expression and activity by the SUR1 Nucleotide Binding Fold 1, Ricard Masia, George Caputa, and Colin G. Nichols

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Nectin-like proteins mediate axon-Schwann cell interactions along the internode and are essential for myelination, Patrice Maurel, Steven Einheber, Jolanta Galinska, Pratik Thaker, Isabel Lam, Marina B. Rubin, Steven S. Scherer, Yoshinuri Murakami, David H. Gutmann, and James L. Salzer

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Preparation of antidepressants for use in preclinical research, Jonathan E. McConathy, Catherine Capello, Nachwa Jarkas, Zachary N. Stowe, and Michael J. Owens

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Whole-mount techniques to evaluate subepithelial cellular populations in the adult mouse intestine, Keely G. McDonald and Rodney D. Newberry

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Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4, Michael D. McLellan, Yumi Kasai, Tracie L. Milner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, and et al.

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PI3K(p110α) inhibitors as anti-cancer agents: Minding the heart, Julie R. McMullen and Patrick Y. Jay

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Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model, Samuel G. Melendez-Lopez, Scott Herdman, Ken Hirata, Min-Ho Choi, Youngchool Choe, Charles Craik, Conor R. Caffrey, Elisabeth Hansell, Jianhua Guo, Samuel L. Stanley Jr., Bibiana Chavez-Munguia, Yen Ting Chen, William R. Roush, James McKerrow, and et al.

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Health care-associated pneumonia and community-acquired pneumonia: A single-center experience, Scott T. Micek, Katherine E. Kollef, Richard M. Reichley, Nareg Roubinian, and Marin H. Kollef

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Addition of vasopressin to norepinephrine as independent predictor of mortality in patients with refractory septic shock: An observational study, Scott T. Micek, Poorvi Shah, James M. Hollands, Rina A. Shah, William D. Shannon, and Marin H. Kollef

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Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: Genes or environment?, Katherine I. Morley, Michael T. Lynskey, Pamela A F Madden, Susan A. Treloar, Andrew C. Heath, and Nicholas G. Martin

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Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model, John D. Morrey, Venkatraman Siddharthan, Aaron L. Olsen, Hong Wang, Justin G. Julander, Jeffery O. Hall, Hua Li, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, and Michael S. Diamond

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Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease, Odity Mukherjee, John SK Kauwe, Kevin Mayo, John C. Morris, and Alison M. Goate

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Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii, Kisaburo Nagamune, Wandy L. Beatty, and L. David Sibley

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Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, and L. David Sibley

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MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent