Submissions from 2018
Epigenomics and metabolomics reveal the mechanism of the APOA2-saturated fat intake interaction affecting obesity, Chao-Qiang Lai, Caren E Smith, Laurence D Parnell, Yu-Chi Lee, Dolores Corella, Paul Hopkins, Bertha A Hidalgo, Stella Aslibekyan, Michael A Province, Devin Absher, Donna K Arnett, Katherine L Tucker, and Jose M Ordovas
Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease, Courtney L Sutphen, Lena McCue, Elizabeth M Herries, Chengjie Xiong, Jack H Ladenson, David M Holtzman, Anne M Fagan, and ADNI
Maternal diet and morbidity factors associated with low birth weight in Haiti: A case-control study, Abdirahim Rashid, Thomas Park, Kenneth Macneal, Lora Iannotti, and Will Ross
Pulmonary arteriovenous malformations in children with hereditary hemorrhagic telangiectasia: A longitudinal study, Katie L Mowers, Lynn Sekarski, Andrew J White, and R. Mark Grady
The burden of prostate cancer in Trinidad and Tobago: One of the highest mortality rates in the world, Wayne A Warner, Fang Fang, Smriti Bajracharya, Vasavi Sundaram, Bettina F Drake, and et al
Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells, Tea Soini, Katja Eloranta, Marjut Pihlajoki, Antti Kyrönlahti, Oyediran Akinrinade, Noora Andersson, Jouko Lohi, Mikko P Pakarinen, David B Wilson, and Markku Heikinheimo
Constriction rate modulation can drive cell size control and homeostasis in C. crescentus, Ambroise Lambert, Aster Vanhecke, Anna Archetti, Seamus Holden, Felix Schaber, Zachary Pincus, Michael T Laub, Erin Goley, and Suliana Manley
Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome, D. André d'Avignon, Patrycja Puchalska, Baris Ercal, YingJu Chang, Shannon E. Martin, Mark J. Graham, Gary J. Patti, Xianlin Han, and Peter A. Crawford
Identification of a rhythmic firing pattern in the enteric nervous system that generates rhythmic electrical activity in smooth muscle, Nick J. Spencer, Timothy J. Hibberd, Lee Travis, Lukasz Wiklendt, Marcello Costa, Hongzhen Hu, Simon J. Brookes, David A. Wattchow, Phil G. Dinning, Damien J. Keating, and Julian Sorensen
Modulation of subsets of cardiac B lymphocytes improves cardiac function after acute injury, Luigi Adamo, Lora J Staloch, Cibele Rocha-Resende, Scot J Matkovich, Wenlong Jiang, Geetika Bajpai, Carla J Weinheimer, Attila Kovacs, Joel D Schilling, Philip M Barger, Deepta Bhattacharya, and Douglas L Mann
Health Status Disparities by Sex, Race/Ethnicity, and Socioeconomic Status in Outpatients With Heart Failure., Yevgeniy Khariton, Michael E Nassif, Laine Thomas, Gregg C Fonarow, Xiaojuan Mi, Adam D DeVore, Carol Duffy, Puza P Sharma, Nancy M Albert, J Herbert Patterson, Javed Butler, Adrian F Hernandez, Fredonia B Williams, Kevin McCague, and John A Spertus
Intensity-modulated radiotherapy for prostate cancer, Ben W Fischer-Valuck, Yuan James Rao, and Jeff M Michalski
Novel drug targets for ductus arteriosus manipulation: Looking beyond prostaglandins, Elaine L Shelton, Gautam K Singh, and Colin G Nichols
SATB2 shows different profiles between appendiceal adenocarcinomas ex goblet cell carcinoids and appendiceal/colorectal conventional adenocarcinomas: An immunohistochemical study with comparison to CDX2, Chen Yang, Li Sun, Lingxin Zhang, Lixin Zhou, Dongfeng Niu, Wenfeng Cao, Zhongwu Li, Xiaozheng Huang, Qiang Kang, Lin Jia, Marina Platik, Xiuli Liu, Jinping Lai, and Dengfeng Cao
Palladin is a neuron-specific translational target of mTOR signaling that regulates axon morphogenesis, Yusuke Umegaki, Antonio Martínez Brotons, Yui Nakanishi, Zhongyue Luo, Hanlu Zhang, Azad Bonni, and Yoshiho Ikeuchi
Decreasing recurrent bowel obstructions, improving quality of life with physiotherapy: Controlled study, Amanda D Rice, Kimberley Patterson, Evette D Reed, Belinda F Wurn, Kristen Robles, Bernhard Klingenberg, Leonard B Weinstock, Janey S. A. Pratt, C. Richard King III, and Lawrence J Wurn
Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis, Rafael Kramann, Flavia Machado, Haojia Wu, Tetsuro Kusaba, Konrad Hoeft, Rebekka K Schneider, and Benjamin D Humphreys
Myeloid conditioning with c-kit-targeted CAR-T cells enables donor stem cell engraftment, Yasuyuki Arai, Uimook Choi, Cristina I Corsino, Sherry M Koontz, Masaki Tajima, Colin L Sweeney, Mary A Black, Steven A Feldman, Mary C Dinauer, and Harry L Malech
Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST, Hsiang-Chih Lu, Vanessa Eulo, Anthony J. Apicelli, Melike Pekmezci, Yu Tao, Jingqin Luo, Angela C. Hirbe, and Sonika Dahiya
Alirocumab in high-risk patients: Observations from the open-label expanded use program, Charles J Glueck, Alan Brown, Anne C Goldberg, James M McKenney, Louis Kantaros, John Stewart, Joseph Elassal, and Andrew Koren
Opportunities for epidemiologists in implementation science: A primer, Gila Neta, Ross C Brownson, and David A Chambers
Outcome trends and safety measures after 30 years of laparoscopic cholecystectomy: A systematic review and pooled data analysis, Philip H Pucher, L. Michael Brunt, Neil Davies, Ali Linsk, Amani Munshi, H Alejandro Rodriguez, Abe Fingerhut, Robert D Fanelli, Horacio Asbun, Rajesh Aggarwal, and SAGES Safe Cholecystectomy Task Force
Validation of a novel scoring system for changes in skeletal manifestations of hypophosphatasia in newborns, infants, and children: The Radiographic Global Impression of Change scale, Michael P Whyte, Kenji P Fujita, Scott Moseley, David D Thompson, and William H McAlister
SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex, Chunling Ma, Fang Wang, Bing Han, Xiaoli Zhong, Fusheng Si, Jian Ye, Eddy C Hsueh, Lynn Robbins, Susan M Kiefer, Yanping Zhang, Pamela Hunborg, Mark A Varvares, Michael Rauchman, and Guangyong Peng
Accuracy of self-perceived risk for common conditions, Phyllis Brawarsky, Katyuska Eibensteiner, Elissa V Klinger, Heather J Baer, George Getty, E John Orav, Graham Colditz, and Jennifer S Haas
Building capacity for evidence-based public health: Reconciling the pulls of practice and the push of research, Ross C Brownson, Jonathan E Fielding, and Lawrence W Green
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease, Nicolai Franzmeier, Anne M Fagan, Katrina Paumier, Tammie Benzinger, John C Morris, Randall J Bateman, and et al.
Low subfrontal dural opening for anterior clinoid meningioma, Michael R. Chicoine
Opportunities and obstacles for deep learning in biology and medicine, Travers Ching, S Joshua Swamidass, and et al
Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines, Kyle Ellrott, Matthew H Bailey, Gordon Saksena, Kyle R Covington, Cyriac Kandoth, Chip Stewart, Julian Hess, Singer Ma, Kami E Chiotti, Michael McLellan, Heidi J Sofia, Carolyn Hutter, Gad Getz, David Wheeler, Li Ding, MC3 Working Group, and The Cancer Genome Atlas Research Network
Dynamic changes during the treatment of pancreatic cancer, Robert A. Wolff, Andrea Wang-Gillam, and et al
Interleukin-7 restores lymphocytes in septic shock: The IRIS-7 randomized clinical trial, Bruno Francois, Andrew H Walton, Jacqueline Unsinger, Teresa Blood, Jane Blood, Richard S Hotchkiss, and et al
Physiological mechanisms of sustained fumagillin-induced weight loss, Jie An, Michael L Patnode, Vanessa K Ridaura, Jeffrey I Gordon, and et al
Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant, Meagan A Jacoby, Eric J Duncavage, Gue Su Chang, Christopher A Miller, Jin Shao, Kevin Elliott, Joshua Robinson, Robert S Fulton, Catrina C Fronick, Michelle O'Laughlin, Sharon E Heath, Iskra Pusic, John S Welch, Daniel C Link, John F DiPersio, Peter Westervelt, Timothy J Ley, Timothy A Graubert, and Matthew J Walter
Prevalence, incidence, and clearance of anal high-risk human papillomavirus infection among HIV-infected men in the SUN study, Pragna Patel, Tim Bush, Erna Milunka Kojic, Lois Conley, Elizabeth R Unger, Teresa M Darragh, Keith Henry, John Hammer, Gerome Escota, Joel M Palefsky, and John T Brooks
Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability., L E Duncan, A Ratanatharathorn, A E Aiello, L M Almli, A B Amstadter, A E Ashley-Koch, D G Baker, J C Beckham, L J Bierut, J Bisson, B Bradley, C-Y Chen, S Dalvie, L A Farrer, S Galea, M E Garrett, J E Gelernter, G Guffanti, M A Hauser, E O Johnson, R C Kessler, N A Kimbrel, A King, N Koen, H R Kranzler, M W Logue, A X Maihofer, A R Martin, M W Miller, R A Morey, N R Nugent, J P Rice, S Ripke, A L Roberts, N L Saccone, J W Smoller, D J Stein, M B Stein, J A Sumner, M Uddin, R J Ursano, D E Wildman, R Yehuda, H Zhao, M J Daly, I Liberzon, K J Ressler, C M Nievergelt, and K C Koenen
Results of ASERTAA, a randomized prospective crossover pharmacogenetic study of immediate-release versus extended-release tacrolimus in African American kidney transplant recipients, Jennifer Trofe-Clark, Daniel C Brennan, Patricia West-Thielke, Michael C Milone, Mary Ann Lim, Robin Neubauer, Vincenza Nigro, and Roy D Bloom
Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: Clinical presentation, diagnosis, management and emerging therapies, Ilia G. Halatchev, Jingsheng Zheng, and Jiafu Ou
TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling, Sarah Evans, Huei-Ping Tzeng, Deborah J Veis, Scot Matkovich, Carla Weinheimer, Attila Kovacs, Philip M Barger, and Douglas L Mann
Dural tears in adult deformity surgery: Incidence, risk factors, and outcomes, Sravisht Iyer, Eric O Klineberg, Lukas P Zebala, Michael P Kelly, Robert A Hart, Munish C Gupta, D Kojo Hamilton, Gregory M Mundis, Daniel Sciubba, Christopher P Ames, Justin S Smith, Virginie Lafage, Douglas Burton, Han Jo Kim, and International Spine Study Group (ISSG)
Phase 1b/2a trial of the superoxide dismutase mimetic GC4419 to reduce chemoradiotherapy-induced oral mucositis in patients with oral cavity or oropharyngeal carcinoma, Carryn M Anderson, Stephen T Sonis, Christopher M Lee, Douglas Adkins, Bryan G Allen, Wenqing Sun, Sanjiv S Agarwala, Madhavi L Venigalla, Yuhchyau Chen, Weining Zhen, Diane R Mould, Jon T Holmlund, Jeffrey M Brill, and John M Buatti
Successful surgical repair and perioperative management of 6-month-old with total anomalous pulmonary venous return in a developing country: Considerations for the treatment of pulmonary hypertension, Lakshmi Gokanapudy, Kenneth Remy, Sathappan Karuppiah, Eneida Melgar Humala, Ibrahim Abdullah, Michael Ruppe, William Schechter, Robert Michler, and Joseph Tobias
A systematic, intensive statistical investigation of data from the Comprehensive Analysis of Reported Drugs (CARD) for compliance and illicit opioid abstinence in substance addiction treatment with buprenorphine/naloxone, Kenneth Blum, David Han, Edward J Modestino, Scott Saunders, A Kennison Roy 3rd, W Jacobs, Darryl S Inaba, David Baron, Marlene Oscar-Berman, Mary Hauser, Rajendra D Badgaiyan, David E Smith, John Femino, and Mark S Gold
Behavioral and transcriptomic analysis of Trem2-null mice: Not all knockout mice are created equal, Silvia S Kang, Aishe Kurti, Kelsey E Baker, Chia-Chen Liu, Marco Colonna, Jason D Ulrich, David M Holtzman, Guojun Bu, and John D Fryer
NetProphet 2.0: Mapping transcription factor networks by exploiting scalable data resources, Yiming Kang, Hien-Haw Liow, Ezekiel J Maier, and Michael R Brent
Zinc inhibits TRPV1 to alleviate chemotherapy-induced neuropathic pain, Jialie Luo, Alexis Bavencoffe, Pu Yang, Jing Feng, Shijin Yin, Aihua Qian, Weihua Yu, Shenbin Liu, Xuan Gong, Tao Cai, Edgar T. Walters, Carmen W. Dessauer, and Hongzhen Hu
15q23 gain in a neonate with a giant omphalocele and multiple co-occurring anomalies, Hui-Fang Zhou, Christopher J. O'Conor, Chiraag Gangahar, and Louis P. Dehner
2D/3D CMR tissue tracking versus CMR tagging in the assessment of spontaneous T2DM rhesus monkeys with isolated diastolic dysfunction, Jie Zheng and et al
3D printing is a transformative technology in congenital heart disease, Shafkat Anwar, Gautam K. Singh, Jacob Miller, Monica Sharma, Peter Manning, Joseph J. Billadello, Pirooz Eghtesady, and Pamela K. Woodard
3D printing of surgical hernia meshes impregnated with contrast agents: In vitro proof of concept with imaging characteristics on computed tomography, David H. Ballard, Udayabhanu Jammalamadaka, Karthik Tappa, Jeffery A. Weisman, Christen J. Boyer, Jonathan Steven Alexander, and Pamela K. Woodard
AAVrh10 gene therapy ameliorates central and peripheral nervous system disease in canine globoid cell leukodystrophy (Krabbe disease), Xuntain Jiang, Daniel S. Ory, and et al
Ability of postoperative delirium to predict intermediate-term postoperative cognitive function in patients undergoing elective surgery at an academic medical centre: Protocol for a prospective cohort study, Amrita Aranake-Chrisinger, Jenny Zhao Cheng, Maxwell R. Muench, Rose Tang, Angela Mickle Washington University School of Medicine in St. Louis, Hannah Maybrier, Nan Lin, Troy Wildes, Eric Lenze, and Michael Simon Avidan
Abnormal microglia and enhanced inflammation-related gene transcription in mice with conditional deletion of Ctcf in Camk2a-Cre-expressing neurons, Bryan E. McGill, Ruteja A. Barve, Susan E. Maloney, Amy Strickland, Nicholas Rensing, Peter L. Wang, Michael Wong, Richard Head, David F. Wozniak, and Jeffrey Milbrandt
A brain electrical activity electroencephalographic-based biomarker of functional impairment in traumatic brain injury: A multi-site validation trial, Daniel Hanley, Leslie S. Prichep, Neeraj Badjatia, Jeffrey Bazarian, Richard Chiacchierini, Kenneth C. Curley, John Garrett, Elizabeth Jones, Rosanne Naunheim, Brian O'Neil, John O'Neill, David W. Wright, and J. Stephen Huff
A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy, Giulia Allavena, Doriana Debellis, Roberto Marotta, Chetanchandra S. Joshi, Indira U. Mysorekar, and Benedetto Grimaldi
Academic orthopaedic leadership: Current challenges and lessons learned, Dane H. Salazar, James H. Herndon, Thomas P. Vail, Joseph D. Zuckerman, and Richard H. Gelberman
A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion, Christopher A. Miller, Christopher Tricarico, Zachary L. Skidmore, Geoffrey L. Uy, Yi-Shan Lee, Anjum Hassan, Michelle D. O'Laughlin, Heather Schmidt, Ling Tian, Eric J. Duncavage, Malachi Griffith, Obi L. Griffith, John S. Welch, and Lukas D. Wartman
Accessible communication tools for surgical site infection monitoring and prevention in joint reconstruction: Feasibility study, Keyin Lu, Christopher J. Chermside-Scabbo, Nikolas E. Marino, Angela Concepcion, Craig Yugawa, Bola Aladegbami, Theodora Paar, Theresa A. St John, Will Ross, John C. Clohisy, and John P. Kirby
Accurate PCR detection of influenza A/B and respiratory syncytial viruses by use of Cepheid Xpert Flu+RSV Xpress Assay in point-of-care settings: Comparison to Prodesse ProFlu+, Daniel M. Cohen, Jennifer Kline, Larissa S. May, Glenn Eric Harnett, Jane Gibson, Stephen Y. Liang, Zubaid Rafique, Carina A. Rodriguez, Kevin M. McGann Sr., Charlotte A. Gaydos, Donna Mayne, David Phillips, and Jason Cohen
A cell-intrinsic interferon-like response links replication stress to cellular aging caused by progerin, Ray Kreienkamp, Simona Graziano, Nuria Coll-Bonfill, Gonzalo Bedia-Diaz, Emily Cybulla, Alessandro Vindigni, Dale Dorsett, Nard Kubben, Luis Francisco Zirnberger Batista, and Susana Gonzalo
Acetabular wedge augments for uncontained tibial plateau defects in revision total knee arthroplasty, Jeffrey B. Stambough, Jacob A. Haynes, Robert L. Barrack, and Ryan M. Nunley
Achieving optimal post-exercise muscle protein remodeling in physically active adults through whole food consumption, Stephan van Vliet, Joseph W. Beals, Isabel G. Martinez, Sarah K. Skinner, and Nicholas A. Burd
A clickable oxysterol photolabel retains NMDA receptor activity and accumulates in neurons, Daniel M. Chen, Luke Ziolkowski, Ann Benz, Mingxing Qian, Charles F. Zorumski, Douglas F. Covey, and Steven Mennerick
A complex relationship between immunity and metabolism in Drosophila diet-induced insulin resistance, Laura Palanker Musselman, Jill L. Fink, Ana R. Grant, Jared A. Gatto, Bryon F. Tuthill II, and Thomas J. Baranski
A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms, Vallmer E. Jordan, Jerilyn A. Walker, Thomas O. Beckstrom, Cody J. Steely, Cullen L. McDaniel, Corey P. St. Romain, The Baboon Genome Analysis Consortium, Kim C. Worley, Jane Phillips-Conroy, Clifford J. Jolly, Jeffrey Rogers, Miriam K. Konkel, and Mark A. Batzer
A connectomic approach to the lateral geniculate nucleus, Josh L. Morgan
A conserved circadian function for the Neurofibromatosis 1 gene, Lei Bai, Yool Lee, Cynthia T. Hsu, Julie A. Williams, Daniel Cavanaugh, Xiangzhong Zheng, Carly Stein, Paula Haynes, Han Wang, David H. Gutmann, and Amita Sehgal
A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array transducers, Satya V.V.N. Kothapalli, Ari Partanen, Lifei Zhu, Michael B. Altman, H Michael Gach, Dennis E. Hallahan, and Hong Chen
Acquired whole-lung mismatched perfusion defects on pulmonary ventilation/perfusion scintigraphy, Andrew W. Bowman, Brittany K. Albers, and Manoj K. Jain
Acupuncture and whole health in the Veterans Administration, Kavitha P. Reddy, David F. Drake, and Benjamin Kligler
Acute control of the sleep switch in Drosophila reveals a role for gap junctions in regulating behavioral responsiveness, Michael Troup, Melvyn HW Yap, Chelsie Rohrscheib, Martyna J. Grabowska, Deniz Ertekin, Roshini Randeniya, Benjamin Kottler, Aoife Larkin, Kelly Munro, Paul J. Shaw, and Bruno van Swinderen
Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study, Xuehong Zhang, Megan Rice, Shelly S. Tworoger, Bernard A. Rosner, A. Heather Eliassen, Rulla M. Tamimi, Amit D. Joshi, Sara Lindstrom, Jing Qian, Graham A. Colditz, Walter C. Willett, Peter Kraft, and Susan E. Hankinson
Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model, Makoto Ishikawa, Takeshi Yoshitomi, Douglas F. Covey, Charles F. Zorumski, and Yukitoshi Izumi
Add-on plasmonic patch as a universal fluorescence enhancer, Jingyi Luan, Jeremiah J. Morrissey, Zheyu Wang, Hamed Gholami Derami, Keng-Ku Liu, Sisi Cao, Qisheng Jiang, Congzhou Wang, Evan D. Kharasch, Rajesh R. Naik, and Srikanth Singamaneni
A direct test of the diathesis–stress model for depression, L Colodro-Conde, B Couvy-Duchesne, G Zhu, WL Coventry, EM Byrne, S Gordon, MJ Wright, GW Montgomery, PAF Madden, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, S Ripke, LJ Eaves, AC Heath, NR Wray, SE Medland, and NG Martin
Administrative evidence-based practices in state chronic disease practitioners, Amy A. Eyler, Cheryl Valko, Ramya Ramadas, Marti Macchi, Zarina Fershteyn, and Ross C. Brownson
Adolescent development of cortical oscillations: Power, phase, and support of cognitive maturation, Scott Marek, Brenden Tervo-Clemmens, Natalie Klein, William Foran, Avniel Singh Ghuman, and Beatriz Luna
Adolescent neurocognitive development and impacts of substance use: Overview of the Adolescent Brain Cognitive Development (ABCD) baseline neurocognition battery, M. Luciana, J. M. Bjork, B. J. Nagel, D. M. Barch, R. Gonzalez, S. J. Nixon, and M. T. Banich
Adropin: An endocrine link between the biological clock and cholesterol homeostasis, D. C. Rao and et al
Adult-onset papular purpuric gloves and socks syndrome, Monica Rosales Santillan, Jessica B. Dietert, and Richard Jahan-Tigh
Adverse events following single dose treatment of lymphatic filariasis: Observations from a review of the literature, Philip J. Budge, Carly Herbert, Britt J. Andersen, and Gary J. Weil
Aerosol-synthesized siliceous nanoparticles: Impact of morphology and functionalization on biodistribution, Philipp Diebolder, Miguel Vazquez-Pufleau, Nilantha Bandara, Cedric Mpoy, Ramesh Raliya, Elijah Thimsen, Pratim Biswas, and Buck E. Rogers
A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis, Christopher Schlosberg and John R. Edwards
A genome-wide association study of idiopathic dilated cardiomyopathy in African Americans, Huichun Xu, Gerald W. Dorn II, Amol Shetty, Ankita Parihar, Tushar Dave, Shawn W. Robinson, Stephen S. Gottlieb, Mark P. Donahue, Gordon F. Tomaselli, William E. Kraus, Braxton D. Mitchell, and Stephen B. Liggett
Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites, Nishanth Uli, Eduardo Michelen-Gomez, Enrique I. Ramos, and Todd E. Druley
Age-specific global epidemiology of hydrocephalus: Systematic review, metanalysis and global birth surveillance, Albert M. Isaacs, Jay Riva-Cambrin, Daniel Yavin, Aaron Hockley, Tamara M. Pringsheim, Nathalie Jette, Brendan Cord Lethebe, Mark Lowerison, Jarred Dronyk, and Mark G. Hamilton
Age trends in 30 day hospital readmissions: US national retrospective analysis, Jay G. Berry, James C. Gay, Karen Joynt Maddox, Eric A. Coleman, Emily M. Bucholz, Margaret R. O'Neill, Kevin Blaine, and Matthew Hall
A gratuitous β-Lactamase inducer uncovers hidden active site dynamics of the Staphylococcus aureus BlaR1 sensor domain, Thomas E. Frederick and Jeffrey W. Peng
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses, Thomas J. Baranski, Aldi T. Kraja, Jill L. Fink, Mary Feitosa, Petra A. Lenzini, Ingrid B. Borecki, Ching-Ti Liu, L. Adrienne Cupples, Kari E. North, and Michael A. Province
A humoral immune response alters the distribution of enzyme replacement therapy in murine mucopolysaccharidosis type I, Steven Q. Le, Shih-hsin Kan, Don Clarke, Valentina Sanghez, Martin Egeland, Kristen N. Vondrak, Terence M. Doherty, Moin U. Vera, Michelina Iacovino, Jonathan D. Cooper, Mark S. Sands, and Patricia I. Dickson
A knock-in tristetraprolin (TTP) zinc finger point mutation in mice: Comparison with complete TTP deficiency, Wi S. Lai, Deborah J. Stumpo, Lianqun Qiu, Roberta Faccio, and Perry J. Blackshear
A liquid-like organelle at the root of motile ciliopathy, Ryan L. Huizar, Chanjae Lee, Alexander A. Boulgakov, Amjad Horani, Fan Tu, Edward M. Marcotte, Steven L. Brody, and John B. Wallingford
Allosteric coupling of CARMIL and V-1 binding to capping protein revealed by hydrogen-deuterium exchange, Britney Johnson, Patrick McConnell, Alex G. Kozlov, Marlene Mekel, Timothy M. Lohman, Michael L. Gross, Gaya K. Amarasinghe, and John A. Cooper
Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors, Jennifer L. Macdonald-Obermann and Linda J. Pike
Altered compensatory cytokine signaling underlies the discrepancy between Flt3–/– and Flt3l–/– mice, Vivek Durai, Prachi Bagadia, Carlos G. Briseño, Derek J. Theisen, Arifumi Iwata, Jesse T. Davidson, Marco Gargaro, Daved H. Fremont, Theresa L. Murphy, and Kenneth M. Murphy
Alternative pathway is essential for glomerular complement activation and proteinuria in a mouse model of membranous nephropathy, Wentian Luo, Florina Olaru, Jeffrey H. Miner, Laurence H. Becker Jr, Johan van der Vlag, Joshua M. Thurman, and Dorin-Bogdan Borza
Alzheimer’s disease and sleep–wake disturbances: Amyloid, astrocytes, and animal models, William M. Vanderheyden, Miranda M. Lim, Erik S. Musiek, and Jason R. Gerstner
A marginalized two-part Beta regression model for microbiome compositional data, Haitao Chai, Hongmei Jiang, Lu Lin, and Lei Liu
A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo, Andrew E.O Hughes, Connie A. Myers, and Joseph C. Corbo
Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation, Courtney Sobieski, Natasha Warikoo, Hong-Jin Shu, and Steven Mennerick
