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Submissions from 2013

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Murine vaginal colonization model for investigating asymptomatic mucosal carriage of streptococcus pyogenes, Michael E. Watson Jr, Hailyn V. Nielsen, Scott J. Hultgren, and Michael G. Caparon

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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling, Katsuhiko Funai, Haowei Song, Li Yin, Irfan J. Lodhi, Xiaochao Wei, Jun Yoshino, Trey Coleman, and Clay F. Semenkovich

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Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology, Kelly R. Monk, Matthew G. Voas, Clara Franzini-Armstrong, Ian S. Hakkinen, and William S. Talbot

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Myocardial ablation of G protein–coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion injury through an anti-intrinsic apoptotic pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn II, Walter J. Koch, and Erhe Gao

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Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection, Herbert W. Virgin and et al

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Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma, Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, and Andrea Wang-Gillam

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Neoadjuvant therapy in operable breast cancer: application to triple negative breast cancer, Foluso O. Ademuyiwa, Matthew J. Ellis, and Cynthia X. Ma

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Neural responses to ambiguity involve domain-general and domain-specific emotion processing systems, Maital Neta, William M. Kelley, and Paul J. Whalen

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Neural signatures of test-potentiated learning in parietal cortex, Steven M. Nelson, Kathleen M. Arnold, Adrian W. Gilmore, and Kathleen B. McDermott

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Neuropathic midfoot deformity: Associations with ankle and subtalar joint motion, David R. Sinacore, David J. Gutekunst, Mary K. Hastings, Michael J. Strube, Kathryn L. Bohnert, Fred W. Prior, and Jeffrey E. Johnson

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Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by western equine encephalitis virus capsid, Daniel C. Peltier, Helen M. Lazear, Jocelyn R. Farmer, Michael S. Diamond, and David J. Miller

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Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process, Chiao-Wen Yang and Emil R. Unanue

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New mutations in flagellar motors identified by whole genome sequencing in Chlamydomonas, Huawen Lin, Nicholas P. Nauman, Alison J. Albee, Silas Hsu, and Susan K. Dutcher

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NGL-2 regulates pathway-specific neurite growth and lamination, synapse formation, and signal transmission in the retina, Florentina Soto, Kelly L. Watkins, Robert E. Johnson, Frank Schottler, and Daniel Kerschensteiner

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Niemann-Pick disease type C clinical database: Cognitive and coordination deficits are early disease indicators, Miriam Stampfer, Susanne Theiss, Yasmina Amraoui, Xuntian Jiang, Sigrid Keller, Daniel S. Ory, Eugen Mengel, Christine Fischer, and Heiko Runz

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Noncoding variation of the gene for ferritin light chain in hereditary and age-related cataract, Thomas M. Bennett, Giovanni Maraini, Chongfei Jin, Wenmin Sun, J. Fielding Hejtmancik, and Alan Shiels

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Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis, Soonjeon Youn, Rebecca L. Ambrose, Jason M. Mackenzie, and Michael S. Diamond

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Normal cognition in transgenic BRI2-Aβ mice, Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W. Dickson, David R. Borchelt, Todd Golde, and Christopher Janus

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Novel insulin sensitizer modulates nutrient sensing pathways and maintains beta-cell phenotype in human islets, Nidhi Rohatgi, Haytham Aly, Connie A. Marshall, William G. McDonald, Rolf F. Kletzien, Jerry R. Colca, and Michael L. McDaniel

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Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs, Erica C. Pehrsson, Kevin J. Forsberg, Molly K. Gibson, Sara Ahmadi, and Gautam Dantas

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Nucear expression of snail is an independent negative prognostic factor in human breast cancer, S Muenst, S. Däster, E C. Obermann, R A. Droeser, W P. Weber, U von Holzen, F Gao, C Viehl, D Oertli, and S D. Soysal

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Obesity, mortality, and life years lost associated with breast cancer in nonsmoking US women, national health interview survey, 1997-2000, Su-Hsin Chang, Lisa M. Pollack, and Graham A. Colditz

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Observer ratings of neighborhoods: Comparison of two methods, Elena M. Andresen, Theodore K. Malmstrom, Mario Schootman, Fredric D. Wolinsky, J. Philip Miller, and Douglas K. Miller

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Occurrence of nodular lymphocyte-predominant Hodgkin lymphoma in Hermansky-Pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects, Luisa Lorenzi, Giovanna Tabellini, William Vermi, Danielle Moratto, Fulvio Porta, Lucia D. Notarangelo, Ornella Patrizi, Silvano Sozzani, Genevieve de Saint Basile, Sylvain Latour, David Pace, Silvia Lonardi, Fabio Facchetti, Raffaele Badolato, and Silvia Parolini

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Oct4/Sox2 binding sites contribute to maintaining hypomethylation of the maternal Igf2/H19 imprinting control region, David L. Zimmerman, Craig S. Boddy, and Christopher S. Schoenherr

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Onchocerciasis: The pre-control association between prevalence of palpable nodules and skin microfilariae, Luc E. Coffeng, Sebatien D. S. Pion, Simon O'Hanlon, Simon Cousens, Adenike O. Abiose, Peter U. Fischer, Jan H. F. Remme, K. Yankum Dadzie, Michele E. Murdoch, Sake J. de Vlas, Maria-Gloria Basanez, Wilma A. Stolk, and Michel Boussinesq

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Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML, Stephen T. Oh and et al

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Opportunities and challenges for successful use of bevacizumab in pediatrics, Amy Barone and Joshua B. Rubin

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Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper, Bradley A. Ford and Carey-Ann D. Burnham

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Optimizing identification of clinically relevant gram-positive organisms by use of the bruker biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry system, Erin McElvania TeKippe, Sunni Shuey, David W. Winkler, Meghan A. Butler, and Carey-Ann Burnham

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p19(ARF) and Ras(V12) offer opposing regulation of DHX33 translation to dictate tumor cell fate, Yandong Zhang, Anthony J. Saporita, and Jason D. Weber

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Pan-genome and comparative genome analyses of Propionibacterium acnes reveal its genomic diversity in the healthy and diseased human skin microbiome, Shuta Tomida, Lin Nguyen, Bor-Han Chiu, Jared Liu, Erica Sodergren, George M. Weinstock, and Huiying Li

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Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets, Xiao Xu, Yuanhao Zhang, Jennie Williams, Eric Antoniou, W. Richard McCombie, Song Wu, Wei Zhu, Nicholas O. Davidson, Paula Denoya, and Ellen Li

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Parapharyngeal neck schwannomas with unusual vascular displacement, Kiran Sargar

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Parenting practices in pregnancy smokers compared to non smokers, Mini Tandon, Xuemei Si, Andy Belden, Ed Spitznagel, Lauren S. Wakschlag, and Joan Luby

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Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital, Jonas Marschall, Marilyn L. Piccirillo, Betsy Foxman, Lixin Zhang, David K. Warren, Jeffrey P. Henderson, and CDC Prevention Epicenters Program

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Patient-specific independent 3D GammaPlan quality assurance for Gamma Knife Perfexion radiosurgery, Maria Mamalui-Hunter, Sridhar Yaddanapudi, Tianyu Zhao, Sasa Mutic, Daniel A. Low, and Robert E. Drzymala

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Pattern recognition receptor MDA5 modulates CD8+ T cell- dependent clearance of west nile virus from the central nervous system, Helen M. Lazear, Amelia K. Pinto, Hilario J. Ramos, Sarah C. Vick, Bimmi Shrestha, Mehul S. Suthar, Michael Gale Jr, and Michael S. Diamond

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PCNA promotes processive DNA end resection by Exo1, Xiaoqing Chen, Sharad C. Paudyal, Re-I Chin, and Zongsheng You

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Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes, Aimee M. Moore, Sanket Patel, Kevin J. Forsberg, Bin Wang, Gayle Bentley, Yasmin Razia, Xuan Qin, Phillip I. Tarr, and Gautam Dantas

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Percutaneous placement of self-expandable metallic stents in patients with obstructive jaundice secondary to metastatic gastric cancer after gastrectomy, Hyun Pyo Hong, Tae-Seok Seo, In-Ho Cha, Jung Rim Yu, Young Jae Mok, Joo Hyeong Oh, Se Hwan Kwon, Sam Soo Kim, and Seung Kwon Kim

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Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses, Vesselin T. Tomov, Lisa C. Osborne, Douglas V. Dolfi, Gregory F. Sonnenberg, Laurel A. Monticelli, Kathleen Mansfield, Herbert W. Virgin, David Artis, and E. John Wherry

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PGMRA: a web server for (phenotype x genotype) many-to-many relation analysis in GWAS, Javier Arnedo, Coral del Val, Gabriel Alejandro de Erausquin, Rocio Romero-Zaliz, Dragan Svrakic, Claude Robert Cloninger, and Igor Zwir

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Phenotypic characteristics of early Wolfram syndrome, Bess A. Marshall, M. Alan Permutt, Alexander R. Paciorkowski, James Hoekel, Roanne Karzon, Jon Wasson, Amy Viehover, Neil H. White, Joshua S. Shimony, Linda Manwaring, Paul Austin, Timothy E. Hullar, Tamara Hershey, and Washington University Wolfram Study Group

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Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors, Chun Wan J. Lai, Alexander V. Kolesnikov, Jeanne M. Frederick, Devon R. Blake, Li Jiang, Jubal S. Stewart, Ching-Kang Chen, Jeffery R. Barrow, Wolfgang Baehr, Vladimir J. Kefalov, and Barry M. Willardson

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Physical activity during recess outdoors and indoors among urban public school students, St. Louis, Missouri, 2010-2011, Irene Tran, Ruth Clark, and Susan B. Racette

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Physiological role of the interaction between CARMIL1 and capping protein, Marc Edwards, Yun Liang, Taekyung Kim, and John A. Cooper

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Pilin and Sortase Residues Critical for Endocarditis- and Biofilm-Associated Pilus Biogenesis in Enterococcus faecalis, Hailyn V. Nielsen, Ana L. Flores-Mireles, Andrew L. Kau, Kimberly A. Kline, Jerome S. Pinkner, Fabrice Neiers, Staffan Normark, Birgitta Henriques-Normark, and Michael G. Caparon

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Plasmacytoid dendritic cells contribute to systemic but not local antiviral responses to HSV infections, Melissa Swiecki, Yaming Wang, Susan Gilfillan, and Marco Colonna

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Point-of-Care glucose analysis in neonates using modified quinoprotein glucose dehydrogenase, Dennis J. Dietzen, Timothy R. Wilhite, Maynard Rasmussen, and Mark Sheffield

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Polyunsaturated fatty acids modulate the association between PIK3CA-KCNMB3 genetic variants and insulin resistance, Ju-Sheng Zheng, Donna K. Arnett, Laurence D. Parnell, Yu-Chi Lee, Yiyi Ma, Caren E. Smith, Kris Richardson, Duo Li, Ingrid B. Borecki, Katherine L. Tucker, Jose M. Ordovas, and Chao-Qiang Lai

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Postradiation osteosarcoma in an older prostate cancer survivor: Case study and literature review with emphasis on geriatric principles, Divya Gumber, Miriam Rodin, and Tanya M. Wildes

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Precise dissection of an Escherichia coli O157:H7 outbreak by single nucleotide polymorphism analysis, George Turabelidze, Steven J. Lawrence, Hongyu Gao, Erica Sodergren, George M. Weinstock, Sahar Abubucker, Todd Wylie, Makedonka Mitreva, Nurmohammad Shaikh, Romesh Gautom, and Phillip I. Tarr

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Predictors of gait speeds and the relationship of gait speeds to falls in men and women with Parkinson disease, Samuel T. Nemanich, Ryan P. Duncan, Leland E. Dibble, James T. Cavanaugh, Terry D. Ellis, Matthew P. Ford, Kenneth B. Foreman, and Gammon M. Earhart

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Prevalence and predictors of compliance with discontinuation of airborne isolation in patients with suspected pulmonary tuberculosis, Benjamin S. Thomas, Erlaine F. Bello, and Todd B. Seto

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Prioritizing potentially druggable mutations with dGene: An annotation tool for cancer genome sequencing data, Runjun D. Kumar, Li-Wei Chang, Matthew J. Ellis, and Ron Bose

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Probabilistic identification of cerebellar cortical neurones across species, Hui Meng, Dora E. Angelaki, and et al

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Prolactin and fMRI response to SKF38393 in the baboon, Brad Miller, Lauren A. Marks, Jonathan M. Koller, Blake J. Newman, G. Larry Bretthorst, and Kevin J. Black

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Prolonged systemic inflammation persistently modifies synaptic plasticity in the hippocampus: Modulation by the stress hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, and Joab Chapman

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Promoting state health department evidence-based cancer and chronic disease prevention: A multi-phase dissemination study with a cluster randomized trial component, Peg Allen, Sonia Sequeira, Rebekah R. Jacob, Adriano Akira Hino, Katherine A. Stamatakis, Jenine K. Harris, Lindsay Elliott, Jon F. Kerner, Ellen Jones, Maureen Dobbins, Elizabeth A. Baker, and Ross C. Brownson

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Protection by immunoglobulin dual-affinity retargeting antibodies against dengue virus, James D. Brien, Soila Sukupolvi-Petty, Katherine L. Williams, Chia-Ying Kao Lam, Michael A. Schmid, Syd Johnson, Eva Harris, and Michael S. Diamond

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Proteomic analysis of Oesophagostomum dentatum (Nematoda) during larval transition, and the effects of hydrolase inhibitors on development, Martina Ondrovics, Katja Silbermayr, Makedonka Mitreva, Neil D. Young, Ebrahim Razzazi-Fazeli, Robin B. Gasser, and Anja Joachim

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Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression, Robert C. Culverhouse; Lucy Bowes; Naomi Breslau; John I. Nurnberger Jr.; Margit Burmeister; David M. Fergusson; Marcus Munafo; Nancy L. Saccone; Laura J. Bierut; and 5-HTTLPR, Stress, and Depression Consortium

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Protocol of a cluster randomized trial of an educational intervention to increase knowledge of living donor kidney transplant among potential transplant candidates, Francis L. Weng, Diane R. Brown, John D. Peipert, Bart Holland, and Amy D. Waterman

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Public health program capacity for sustainability: A new framework, Sarah F. Schell, Douglas A. Luke, Michael W. Schooley, Michael B. Elliott, Stephanie H. Herbers, Nancy B. Mueller, and Alicia C. Bunger

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Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles, Melany N. Lopez, Timothy J. Wilding, and James E. Huettner

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Quality assurance of radiotherapy in the ongoing EORTC 22042–26042 trial for atypical and malignant meningioma: Results from the dummy runs and prospective individual case Reviews, Mehtap Coskun, William Straube, Coen W. Hurkmans, Christos Melidis, Patricia F. de Haan, Salvador Villa, Sandra Collette, and Damien C. Weber

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Quantification of heterogeneity observed in medical images, Frank J. Brooks and Perry W. Grigsby

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Quantitative analysis of PiB-PET with FreeSurfer ROIs, Yi Su, Gina M. D'Angelo, Andrei G. Vlassenko, Gongfu Zhou, Abraham Z. Snyder, Daniel S. Marcus, Tyler M. Blazey, Jon J. Christensen, Shivangi Vora, John C. Morris, Mark A. Mintun, and Tammie L. S. Benzinger

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Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: Assessment of technical and inter-individual variation, Richard J. Perrin, Jacqueline E. Payton, James P. Malone, Petra Gilmore, Alan E. Davis, Chengjie Xiong, Anne M. Fagan, R. Reid Townsend, and David M. Holtzman

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Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1, Kooresh I. Shoghi, Jinbin Xu, Yi Su, June He, Douglas Rowland, Ying Yan, Joel R. Garbow, Zhude Tu, Lynne A. Jones, Ryuji Higashikubo, Kenneth T. Wheeler, Ronald A. Lubet, Robert H. Mach, and Ming You

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Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury, Dongjun Guo, Linghui Zeng, David L. Brody, and Michael Wong

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Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy, James K. Ching and Conrad C. Weihl

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Rapid quantitative pharmacodynamic imaging by a novel method: Theory, simulation testing and proof of principle, Kevin J. Black, Jonathan M. Koller, and Brad D. Miller

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RAPID-SELEX for RNA aptamers, Kylan Szeto, David R. Latulippe, Abdullah Ozer, John M. Pagano, Brian S. White, David Shalloway, John T. Lis, and Harold G. Craighead

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Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype, Eline van Meel, Daniel J. Wegner, Paul Cliften, Marcia C. Willing, Frances V. White, Stuart Kornfeld, and F. Sessions Cole

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Rational design of microRNA-siRNA chimeras for multifunctional target suppression, Zhou Jiang, Weijun Liu, Yuhui Wang, Zhen Gao, Ge Gao, and Xiaowei Wang

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Reassessing the role of DotF in the Legionella pneumophila type IV secretion system, Molly C. Sutherland, Kelsey A. Binder, Phillip Y. Cualing, and Joseph P. Vogel

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Recent characterizations of MscS and its homologs provide insight into the basis of ion selectivity in mechanosensitive channels, Grigory Maksaev and Elizabeth S. Haswell

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Recruitment and retention of participants in a pragmatic randomized intervention trial at three community health clinics: Results and lessons learned, Erica T. Warner, Russell E. Glasgow, Karen M. Emmons, Gary G. Bennett, Sandy Askew, Bernard Rosner, and Graham A. Colditz

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Regional control of Drosophila gut stem cell proliferation: EGF establishes GSSC proliferative set point & controls emergence from quiescence, Marie Strand and Craig A. Micchelli

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Regulation of hematopoietic stem cell activity by inflammation, Laura G. Schuettpelz and Daniel C. Link

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Regulation of Rab5 Function during Phagocytosis of Live Pseudomonas aeruginosa in Macrophages, Sushmita Mustafi, Nathalie Rivero, Joan C. Olson, Philip D. Stahl, and M Alejandro Barbieri

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Reliability of clinically relevant 3D foot bone angles from quantitative computed tomography, David J. Gutekunst, Lu Liu, Tao Ju, Fred W. Prior, and David R. Sinacore

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Reliable sex and strain discrimination in the mouse vomeronasal organ and accessory olfactory bulb, Illya I. Tolokh, Xiaoyan Fu, and Timothy E. Holy

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Renal abscess caused by a Providencia stuartii isolate biochemically misidentified as Pasteurella, Robin R. Chamberland, Erin McElvania TeKippe, Carey-Ann D. Burnham, and Donald J. Kennedy

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Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behavior in mice, Kristen C. Klemenhagen, Scott P. O'Brien, and David L. Brody

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Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart, Kory J. Lavine, Attila Kovacs, Carla Weinheimer, and Douglas L. Mann

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Reproducibility of the heat/capsaicin skin sensitization model in healthy volunteers, Lara F. Cavallone, Karen Frey, Michael C. Montana, Jeremy Joyal, Karen J. Regina, Karin L. Petersen, and Robert W. Gereau IV

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Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters, Helena Petrosova, Petra Pospisilova, Michal Strouhal, Darina Cejkova, Marie Zobanikova, Lenka Mikalova, Erica Sodergren, George M. Weinstock, and David Smajs

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Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations, Gustavo Deco, Adrian Ponce Alvarez, Dante Mantini, Gian Luca Romani, Patric Hagmann, and Maurizio Corbetta

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Results of initial low-dose computed tomographic screening for lung cancer, Timothy R. Church, William C. Black, Denise R. Aberle, Christine D. Berg, Kathy L. Clingan, Fenghai Duan, Richard M. Fagerstrom, Ilana F. Gareen, David S. Gierada, Gordon C. Jones, Irene Mahon, Pamela M. Marcus, JoRean D. Sicks, Amanda Jain, and Sarah Baum

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Results of the two incidence screenings in the National Lung Screening Trial, David S. Gierada and et al

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Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, and Robert O. Heuckeroth

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RETRACTED ARTICLE: The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination, Baeck-seung Lee, Joseph D. Dekker, Bum-kyu Lee, Vishwanath R. Iyer, Barry P. Sleckman, Arthur L. Shaffer III, Gregory C. Ippolito, and Philip W. Tucker

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Retrophylogenomics place tarsiers on the evolutionary branch of anthropoids, Gerrit Hartig, Gennady Churakov, Wesley C. Warren, Jürgen Brosius, Wojciech Makalowski, and Jürgen Schmitz

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Retrotransposition of gene transcripts leads to structural variation in mammalian genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing and Analysis Program and Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, and David Haussler

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Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition, Lora L. Iannotti, Indi Trehan, and Mark J. Manary

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RidA proteins prevent metabolic damage inflicted by PLP-dependent dehydratases in all domains of life, Jennifer A. Lambrecht, George E. Schmitz, and Diana M. Downs

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RNA helicase signaling is critical for type I interferon production and protection against rift valley fever virus during mucosal challenge, Megan E. Ermler, Ekaterina Yerukhim, Jill Schriewer, Stefan Schattgen, Zachary Traylor, Adam R. Wespiser, Daniel R. Caffrey, Zhijian J. Chen, Charles H. King, Michael Gale Jr., Marco Colonna, Katherine A. Fitzgerald, R. Mark L. Buller, and Amy G. Hise