Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy

Authors

• Jingxuan Guo, Washington University in St. Louis
• Huanzhu Jiang, Washington University in St. Louis
• David Schuftan, Washington University in St. Louis
• Jonathan D Moreno, Washington University School of Medicine in St. Louis
• Ghiska Ramahdita, Washington University in St. Louis
• Lavanya Aryan, Washington University in St. Louis
• Druv Bhagavan, Washington University in St. Louis
• Jonathan Silva, Washington University in St. Louis
• Nathaniel Huebsch, Washington University School of Medicine in St. Louis

Journal

iScience

Publication Date

5-10-2024

Volume

27

Issue

6

First Page

109954

Document Type

Open Access Publication

DOI

10.1016/j.isci.2024.109954

Rights and Permissions

Guo J, Jiang H, Schuftan D, Moreno JD, Ramahdita G, Aryan L, Bhagavan D, Silva J, Huebsch N. Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy. iScience. 2024 May 10;27(6):109954. doi: 10.1016/j.isci.2024.109954 This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.

Recommended Citation

Guo, Jingxuan; Jiang, Huanzhu; Schuftan, David; Moreno, Jonathan D; Ramahdita, Ghiska; Aryan, Lavanya; Bhagavan, Druv; Silva, Jonathan; and Huebsch, Nathaniel, "Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy." iScience. 27, 6. 109954 (2024).
https://digitalcommons.wustl.edu/oa_4/5355

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.