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Submissions from 2023

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Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype, Paige E Lawler, James G Bollinger, Suzanne E Schindler, Cynthia R Hodge, Nicolas J Iglesias, Vishal Krishnan, John B Coulton, Yan Li, David M Holtzman, and Randall J Bateman

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Associated radiation exposure from medical imaging and excess lifetime risk of developing cancer in pediatric patients with pulmonary hypertension, Malini Mahendra, Philip Chu, Elena K Amin, Hythem Nawaytou, James R Duncan, Jeffrey R Fineman, and Rebecca Smith-Bindman

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Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment, Michael Chiorazzi, Bradley Krasnick, Keenan J Robbins, Zachary Skidmore, Jacqueline Mudd, Ye Bi, S Peter Goedegebuure, Malachi Griffith, Obi Griffith, Abimbola Oyedeji, Ryan C Fields, and et al.

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Blood neurofilament light levels predict non-relapsing progression following anti-CD20 therapy in relapsing and primary progressive multiple sclerosis: Findings from the ocrelizumab randomised, double-blind phase 3 clinical trials, Amit Bar-Or, Anne H Cross, and et al.

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Characteristics of patients with pulmonary arterial hypertension from an innovative, comprehensive real-world patient data repository, Harrison W Farber, Murali M Chakinala, Michelle Cho, Robert P Frantz, Andrew Frick, Lisa Lancaster, Scott Milligan, Ronald Oudiz, Sumeet Panjabi, Yuen Tsang, and Steven D Nathan

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Clinical outcomes of patients with unresectable primary liver cancer treated with MR-guided stereotactic body radiation therapy: A six-year experience, Re-I Chin, Joshua P Schiff, Anirudh Bommireddy, Kylie H Kang, Neal Andruska, Alexander T Price, Olga L Green, Yi Huang, Kevin Korenblat, Parag J Parikh, Jefferey Olsen, Pamela P Samson, Lauren E Henke, Hyun Kim, and Shahed N Badiyan

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Complete hydatidiform mole with a coexisting viable male fetus detected by cell-free DNA, Mackenzie Lemieux, Lauren Kus, Kali Stewart, Mai He, Jackson Rowe, Matthew Brady, Katherine Bligard, Megan Lawlor, and Jeannie Kelly

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Coping strategies and symptoms of mental health disorders among people with HIV initiating HIV care in Cameroon, Angela M Parcesepe, Lindsey M Filiatreau, Amanda Gomez, Peter Vanes Ebasone, Anastase Dzudie, Brian W Pence, Milton Wainberg, Marcel Yotebieng, Kathryn Anastos, Eric Pefura-Yone, Denis Nsame, Rogers Ajeh, and Denis Nash

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Dietary patterns are not associated with disease activity among patients with inflammatory conditions of the pouch in a prospective cohort, Edward L Barnes, Poonam Beniwal-Patel, Parakkal Deepak, Laura Raffals, Maia Kayal, Marla Dubinsky, Shannon Chang, Peter D R Higgins, Jennifer I Barr, Chelsea Anderson, Raymond K Cross, Millie D Long, and Hans H Herfarth

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Economic impact of recurrent Clostridioides difficile infection in the USA: A systematic literature review and cost synthesis, Kelly R Reveles, Min Yang, Viviana Garcia-Horton, Marie Louise Edwards, Amy Guo, Thomas Lodise, Markian Bochan, Glenn Tillotson, and Erik R Dubberke

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Encoding and storage of information in mechanical metamaterials, Zhiqiang Meng, Hujie Yan, Mingchao Liu, Wenkai Qin, Guy M Genin, and Chang Qing Chen

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Enhanced 3D visualization of human fallopian tube morphology using a miniature optical coherence tomography catheter, Hongbo Luo, Shuying Li, Sitai Kou, Yixiao Lin, Ian S Hagemann, and Quing Zhu

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Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor, Mithila Sawant, Audrey Wilson, Dhivya Sridaran, Kiran Mahajan, Christopher J O'Conor, Ian S Hagemann, Jingqin Luo, Cody Weimholt, Tiandao Li, Juan Carlos Roa, Akhilesh Pandey, Xinyan Wu, and Nupam P Mahajan

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Esthesioneuroblastoma: Management of the N0 neck, Stephanie J. Youssef and Nyssa Fox Farrell

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Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major, Somrita Basu, Mattie C. Pawlowic, Fong-Fu Hsu, Geoff Thomas, and Kai Zhang

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Exploring the natural history of intrinsic capacity impairments: Longitudinal patterns in the 10/66 study, Emmanuel Gonzalez-Bautista, Jorge Jesus Llibre-Guerra, Ana L Sosa, Isaac Acosta, Sandrine Andrieu, Daisy Acosta, Juan de Jesús Llibre-Rodríguez, and Matthew Prina

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Future considerations in the diagnosis and treatment of compressive neuropathies of the upper extremity, Elizabeth A Graesser, Christopher J Dy, and David M Brogan

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GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models, Vyron Gorgogietas, Cris Brown, Fumihiko Urano, and et al.

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Healthcare costs of Clostridioides difficile infection in commercially insured younger adults, John M Sahrmann, Margaret A Olsen, Matthew R Keller, Holly Yu, and Erik R Dubberke

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IBD Camp Oasis: A look at participants' social-emotional well-being and protective factors during camp and beyond, Namita Singh, Steven J Steiner, Rebecca Fauth, Danyel Moosmann, Janis Arnold, Abdul Elkadri, Daniel Marinoni, Laurel Molloy, Becky Johnson Rescola, Jeanne Tung, and Elizabeth C Utterson

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Identifying the neural correlates of anticipatory postural control: A novel fMRI paradigm, Jo Armour Smith, Rongwen Tain, Kelli G Sharp, Laura M Glynn, Linda R Van Dillen, Korinne Henslee, Jesse V Jacobs, and Steven C Cramer

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Improving the diagnostic yield of high-resolution esophageal manometry for GERD: The "straight leg-raise" international study, Stefano Siboni, Benjamin D Rogers, Garrett Greenan, C Prakash Gyawali, and et al.

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Multicenter randomized trial of carpal tunnel release with ultrasound guidance versus mini-open technique, Kyle R Eberlin, Benjamin P Amis, Thomas P Berkbigler, Christopher J Dy, Mark D Fischer, James L Gluck, F Thomas D Kaplan, Thomas J McDonald, Larry E Miller, Alexander Palmer, Paul E Perry, Marc E Walker, and James F Watt

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Multiparametric immunoimaging maps inflammatory signatures in murine myocardial infarction models, Alexander Maier, Gyu Seong Heo, Robert J Gropler, Yongjian Liu, and et al.

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Neuroinflammation and white matter alterations in occupational manganese exposure assessed by diffusion basis spectrum imaging, Susan R Criswell, Susan Searles Nielsen, Irene M Faust, Joshua S Shimony, Robert L White 3rd, Jason Lenox-Krug, and Brad A Racette

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Organization of the human intestine at single-cell resolution, John W Hickey, Zhengyan Zhang, Yiing Lin, and et al.

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Plasma proteomic patterns show sex differences in early concentric left ventricular remodeling, Anne-Mar van Ommen, Ernest Diez Benavente, N. Charlotte Onland-Moret, Gideon B. Valstar, Maarten J. Cramer, Frans H. Rutten, Arco J. Teske, Roxana Menken, Leonard Hofstra, Igor I. Tulevski, Nancy Sweitzer, G. Aernout Somsen, and Hester M. den Ruijter

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Point-of-care tissue oxygenation assessment with SnapshotNIR for alloplastic and autologous breast reconstruction, William R. Moritz, John Daines, Joani M. Christensen, Terence Myckatyn, Justin M. Sacks, and Amanda M. Westman

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Postmortem diagnosis of very long chain acyl-CoA dehydrogenase (VLCAD) deficiency in a neonate with sudden cardiac death, Prapti Singh, Deirdre Amaro, Olugbemisola Obi, Fnu Kiran, Erin Hediger, Tomi L Toler, Patricia I Dickson, and Dorothy K Grange

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Rapid and sustained improvements in Generalized Pustular Psoriasis Physician Global Assessment scores with spesolimab for treatment of generalized pustular psoriasis flares in the randomized, placebo-controlled Effisayil 1 study, Boni E Elewski, Mark G Lebwohl, Milan J Anadkat, Jonathan Barker, Kamran Ghoreschi, Shinichi Imafuku, Ulrich Mrowietz, Ling Li, Manuel Quaresma, Christian Thoma, and Hervé Bachelez

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Real-world outcomes associated with poly(ADP-ribose) polymerase inhibitor monotherapy maintenance in patients with primary advanced ovarian cancer, John K Chan, Jinan Liu, Jinlin Song, Cheryl Xiang, Eric Wu, Linda Kalilani, Jean A. Hurteau, and Premal H. Thaker

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Recurrent myocardial injury leads to disease tolerance in a murine model of stress-induced cardiomyopathy, Sajal K Tiwary, Tomohiro Hayashi, Attila Kovacs, and Douglas L Mann

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Safety and efficacy of ceftolozane/tazobactam plus metronidazole versus meropenem from a phase 2, randomized clinical trial in pediatric participants with complicated intra-abdominal infection, Carl-Christian A. Jackson, Jason Newland, Nataliia Dementieva, Julia Lonchar, Feng-Hsiu Su, Jennifer A. Huntington, Mekki Bensaci, Myra W. Popejoy, Matthew G. Johnson, Carisa De Anda, Elizabeth G. Rhee, and Christopher J. Bruno

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Staphylococcus aureus bacteremia in pediatric patients: Uncovering a rural health challenge, Kyle J Whittington, Sara M Malone, Patrick G Hogan, Faria Ahmed, JessieAnn Flowers, Grace Milburn, John J Morelli, Jason G Newland, and Stephanie A Fritz

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Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy, Vsevolod Cheburkanov, Junwei Du, David M. Brogan, Mikhail Y. Berezin, and Vladislav V. Yakovlev

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Exploratory genome-wide analyses of cortical inhibition, facilitation, and plasticity in late-life depression, Rafae A Wathra, Xiaoyu Men, Samar S M Elsheikh, Victoria S Marshe, Tarek K Rajji, Jennifer I Lissemore, Benoit H Mulsant, Jordan F Karp, Charles F Reynolds 3rd, Eric J Lenze, Zafiris J Daskalakis, Daniel J Müller, and Daniel M Blumberger

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MicroRNA-145 and microRNA-486 are potential serum biomarkers for vascular calcification, Sara Fernández-Villabrille, Beatriz Martín-Carro, Julia Martín-Vírgala, Cristina Alonso-Montes, Carmen Palomo-Antequera, Raúl García-Castro, Susana López-Ongil, Adriana S Dusso, José Luis Fernández-Martín, Manuel Naves-Díaz, Jorge B Cannata-Andía, Natalia Carrillo-López, and Sara Panizo

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Validation of a Farsi version of the Eating Disorder Examination Questionnaire (F-EDE-Q) in adolescents and university students from Iran, Reza N Sahlan, Jessica F Saunders, Patrycja Klimek-Johnson, Alexandra D Convertino, Jason M Lavender, Ellen E Fitzsimmons-Craft, and Jason M Nagata

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Esophageal secondary peristalsis following acid infusion and chemical clearance correlate with mucosal integrity and acid sensitivity in GERD patients, Ming-Wun Wong, Jui-Sheng Hung, Wei-Yi Lei, Tso-Tsai Liu, Chih-Hsun Yi, Shu-Wei Liang, Chandra Prakash Gyawali, Jen-Hung Wang, and Chien-Lin Chen

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A moment kernel machine for clinical data mining to inform medical decision making, Yao-Chi Yu, Wei Zhang, David O'Gara, Jr-Shin Li, and Su-Hsin Chang

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Epigenome-wide association study identifies novel genes associated with ischemic stroke, Hao Peng, Helena Palma-Gudiel, Carolina Soriano-Tarraga, Jordi Jimenez-Conde, Mingzhi Zhang, Yonghong Zhang, and Jinying Zhao

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ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment, Jeffrey D Steimle, Chul Kim, Megan Rowton, Rangarajan D Nadadur, Zhezhen Wang, Matthew Stocker, Andrew D Hoffmann, Erika Hanson, Junghun Kweon, Tanvi Sinha, Kyunghee Choi, Brian L Black, John M Cunningham, Ivan P Moskowitz, and Kohta Ikegami

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Histidine-rich protein II nanoparticle delivery of heme iron load drives endothelial inflammation in cerebral malaria, Suong T Nguyen, Daniel Du, Daniel Wychrij, Matthew D Cain, Qingping Wu, Robyn S Klein, Ilaria Russo, and Daniel E Goldberg

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IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system, Maryamsadat Seyedsadr, Tabish H Khan, Ulrike Lorenz, and et al.

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Inclusive recruitment strategies to maximize sociodemographic diversity among participants: A St. Louis case study, Chelsey R. Carter, Julia Maki, Nicole Ackermann, and Erika A. Waters

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Neuraminidase activity modulates cellular coinfection during influenza A virus multicycle growth, Zijian Guo, Yuanyuan He, Jian Xu, Ananya N. Benegal, Steven L. Brody, and Michael D. Vahey

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On the dependent recognition of some long zinc finger proteins, Zheng Zuo, Timothy Billings, Michael Walker, Petko M Petkov, Polly M Fordyce, and Gary D Stormo

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A list-mode multi-energy window low-count SPECT reconstruction method for isotopes with multiple emission peaks, Md Ashequr Rahman, Zekun Li, Zitong Yu, Richard Laforest, Daniel L J Thorek, and Abhinav K Jha

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A simplified method to correct saturation of arterial input function for cardiac magnetic resonance first-pass perfusion imaging: Validation with simultaneously acquired PET, Ran Li, Masoud Edalati, David Muccigrosso, Jeffrey M C Lau, Richard Laforest, Pamela K Woodard, and Jie Zheng

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Continuous positive airway pressure increases CSF flow and glymphatic transport, Burhan Ozturk, Sunil Koundal, Ehab Al Bizri, Xinan Chen, Zachary Gursky, Feng Dai, Andrew Lim, Paul Heerdt, Jonathan Kipnis, Allen Tannenbaum, Hedok Lee, and Helene Benveniste

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Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution, Ryann M Fame, Yong Zhang, Michael J Holtzman, and et al.

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Heterogeneity in the effect of marked weight loss on metabolic function in women with obesity, Bettina Mittendorfer, Brandon D. Kayser, Mihoko Yoshino, Jun Yoshino, Jeramie D. Watrous, Mohit Jain, J. Christopher Eagon, Bruce W. Patterson, and Samuel Klein

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Structural specializations of the sperm tail, Miguel Ricardo Leung, Jianwei Zeng, Xiangli Wang, Marc C Roelofs, Wei Huang, Riccardo Zenezini Chiozzi, Johannes F Hevler, Albert J R Heck, Susan K Dutcher, Alan Brown, Rui Zhang, and Tzviya Zeev-Ben-Mordehai

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β Cell function after Roux-en-Y gastric bypass surgery or reduced energy intake alone in people with obesity, Bettina Mittendorfer, Bruce W. Patterson, Faidon Magkos, Mihoko Yoshino, David P. Bradley, J. Christopher Eagon, and Samuel Klein

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Interplay between VSD, pore, and membrane lipids in electromechanical coupling in HCN channels, Ahmad Elbahnsi, John Cowgill, Verena Burtscher, Linda Wedemann, Luise Zeckey, Baron Chanda, and Lucie Delemotte

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Parents' perspectives on the utility of genomic sequencing in the neonatal intensive care unit, Amy A Lemke, Kevin M Bowling, and et al.

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Healthy lifestyle index and risk of cardiovascular disease among postmenopausal women with normal body mass index, Rita Peila, Xiaonan Xue, Qibin Qi, Andrew J Dannenberg, Matthew A Allison, Karen C Johnson, Michael J LaMonte, Robert A Wild, Bernhard Haring, Kathy Pan, Hilary A Tindle, Randi Foraker, Nazmus Saquib, Ana Barac, and Thomas E Rohan

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Long-term outcomes and molecular correlates of sotorasib efficacy in patients with pretreated KRAS G12C-mutated non-small-cell lung cancer: 2-year analysis of CodeBreaK 100, Grace K Dy, Ramaswamy Govindan, and et al.

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Robust acoustic trapping and perturbation of single-cell microswimmers illuminate three-dimensional swimming and ciliary coordination, Mingyang Cui, Susan K Dutcher, Philip V Bayly, and J Mark Meacham

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Striatal dopamine synthesis and cognitive flexibility differ between hormonal contraceptive users and nonusers, Caitlin M Taylor, Daniella J Furman, Anne S Berry, Robert L White, William J Jagust, Mark D'Esposito, and Emily G Jacobs

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A review of social media platform policies that address cannabis promotion, marketing and sales, Carla J Berg, Cassidy R LoParco, Yuxian Cui, Alexandria Pannell, Grace Kong, Lynniah Griffith, Katelyn F Romm, Y Tony Yang, Yan Wang, and Patricia A Cavazos-Rehg

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Use of novel structural features to identify urinary biomarkers during acute kidney injury that predict progression to chronic kidney disease, Jennifer R Charlton, Teng Li, Teresa Wu, Kimberly deRonde, Yanzhe Xu, Edwin J Baldelomar, and Kevin M Bennett

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Genetic deletion of skeletal muscle iPLA2γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism, Sung Ho Moon, Beverly Gibson Dilthey, Shaoping Guan, Harold F Sims, Sara K Pittman, Amy L Keith, Christopher M Jenkins, Conrad C Weihl, and Richard W Gross

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Personalized [177Lu]Lutetium-PSMA therapy for patients with pre-treated castration-resistant prostate cancer: A single institution experience from a comprehensive cancer centre, Wolfgang Thaiss, Friedemann Zengerling, Julia Friedrich, Veronika Hechler, Michael Grunert, Christian Bolenz, Thomas Wiegel, Ambros J Beer, and Vikas Prasad

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The upper and lower respiratory tract microbiome in severe aspiration pneumonia, Georgios D Kitsios, Janet S Lee, and et al.

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Treatment decisions and the use of MEK inhibitors for children with neurofibromatosis type 1-related plexiform neurofibromas, Amy E Armstrong, Allan J Belzberg, John R Crawford, Angela C Hirbe, and Zhihong J Wang

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Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis, Dustin G Shaw, Kelly Monroe, Rodney Newberry, and et al.

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A refined, controlled 16S rRNA gene sequencing approach reveals limited detection of cerebrospinal fluid microbiota in children with bacterial meningitis, Christopher E. Pope, Kathryn B. Whitlock, Paul Hodor, David D. Limbrick Jr, Patrick J. McDonald, Jason Hauptman, Lucas R Hoffman, and Tamara D. Simon

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Comprehensive functional characterization of SGCB coding variants predicts pathogenicity in limb-girdle muscular dystrophy type R4/2E, Chengcheng Li, Jackson Wilborn, Sara Pittman, Jil Daw, Jorge Alonso-Pérez, Jordi Díaz-Manera, Conrad C. Weihl, and Gabe Haller

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Evaluation of the NG-Test CARBA 5 lateral flow assay with an IMP-2-producing Morganella morganii and other Morganellaceae, Nicole J. Tarlton, Meghan A. Wallace, Robert F. Potter, Kailun Zhang, Gautam Dantas, Erik R. Dubberke, Carey-Ann D. Burnham, and Melanie L. Yarbrough

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Gene therapy ameliorates spontaneous seizures associated with cortical neuron loss in a Cln2R207X mouse model, Keigo Takahashi, Elizabeth M. Eultgen, Sophie H. Wang, Nicholas R. Rensing, Hemanth R. Nelvagal, Joshua T. Dearborn, Olivier Danos, Nicholas Buss, Mark S. Sands, Michael Wong, and Jonathan D. Cooper

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Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production, Shyamala Thirunavukkarasu, Mushtaq Ahmed, Bruce A. Rosa, Mark Boothby, Sung Hoon Cho, Javier Rangel-Moreno, Stanley K. Mbandi, Valérie Schreiber, Ananya Gupta, Joaquin Zuniga, Makedonka Mitreva, Deepak Kaushal, Thomas J. Scriba, and Shabaana A. Khader

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Polypill eligibility for patients with heart failure with reduced ejection fraction in the ASIAN-HF registry: A cross-sectional analysis, Aishwarya Vijay, Wan Ting Tay, Tiew-Hwa K Teng, Kanako Teramoto, Jasper Tromp, Wouter Ouwerkerk, Seet Yoong Lo, Wataru Shimizu, Mark D Huffman, Carolyn S P Lam, Chanchal Chandramouli, and Anubha Agarwal

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Polypill eligibility for patients with heart failure with reduced ejection fraction in the ASIAN-HF registry: A cross-sectional analysis, Aishwarya Vijay, Wan Ting Tay, Tiew-Hwa K. Teng, Kanako Teramoto, Jasper Tromp, Wouter Ouwerkerk, Seet Yoong Lo, Wataru Shimizu, Mark D. Huffman, Carolyn S P Lam, Chanchal Chandramouli, and Anubha Agarwal

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Assessing the feasibility of economic approaches to prevent substance abuse among adolescents: Protocol for a mixed methods study, Rachel Brathwaite, Massy Mutumba, Jacqueline Nanteza, Lindsey M Filiatreau, Herbert Migadde, Phionah Namatovu, Betina Nabisere, James Mugisha, Abel Mwebembezi, and Fred M Ssewamala

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Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model, Florian Olde Heuvel, Sanjay Jain, and et al.

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Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis, Yanan Li, Wei Yang, Helen C Wang, Riddhi M Patel, Emily B Casey, Elisabeth Denby, and Jeffrey A Magee

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DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1, Andrew R Findlay, May M Paing, Jil A Daw, Meade Haller, Rocio Bengoechea, Sara K Pittman, Shan Li, Feng Wang, Timothy M Miller, Heather L True, Tsui-Fen Chou, and Conrad C Weihl

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Embryonic vitamin D deficiency programs hematopoietic stem cells to induce type 2 diabetes, Jisu Oh, Amy E Riek, Kevin T Bauerle, Adriana Dusso, Kyle P McNerney, Ruteja A Barve, Isra Darwech, Jennifer E Sprague, Clare Moynihan, Rong M Zhang, Greta Kutz, Ting Wang, Xiaoyun Xing, Daofeng Li, Marguerite Mrad, Nicholas M Wigge, Esmeralda Castelblanco, Monika Bambouskova, Richard D Head, Mark S Sands, Carlos Bernal-Mizrachi, and et al.

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Impact of diagnosis to treatment interval in patients with newly diagnosed mantle cell lymphoma, Narendranath Epperla, Mary-Kate Malecek, Brad S Kahl, Nancy L Bartlett, and et al.

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Large, nested variant of urothelial carcinoma s enriched with activating mutations in Fibroblast Growth Factor Receptor-3 among other targetable mutations, Yaser Gamallat, Mitra Afsharpad, Soufiane El Hallani, Christopher A Maher, Nimira Alimohamed, Eric Hyndman, and Tarek A Bismar

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Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: Data from five prospective clinical trials, Christine Lee, Thomas Louie, Lindy Bancke, Beth Guthmueller, Adam Harvey, Paul Feuerstadt, Sahil Khanna, Robert Orenstein, and Erik R Dubberke

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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis, Feiyang Ma, Eynav Klechevsky, and et al.

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Three-dimensional imaging and quantification of mouse ovarian follicles via optical coherence tomography, Marcello Magri Amaral, Aixia Sun, Yilin Li, Chao Ren, Anh Blue Truong, Saumya Nigam, Zexu Jiao, Ping Wang, and Chao Zhou

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In vitro and in vivo efficacy of a stroma-targeted, tumor microenvironment responsive oncolytic adenovirus in different preclinical models of cancer, Ana Alfano, Eduardo G A Cafferata, Mariela Gangemi, Alejandro Nicola Candia, Cristian M Malnero, Ismael Bermudez, Mauricio Vargas Lopez, Gregorio David Ríos, Cecilia Rotondaro, Nicasio Cuneo, David T Curiel, Osvaldo L Podhajcer, and Maria Veronica Lopez

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Adaptation of a mobile interactive obesity treatment approach for early severe mental illness: Protocol for a mixed methods implementation and pilot randomized controlled trial, Ginger E Nicol, Madeline O Jansen, Amanda R Ricchio, Julia A Schweiger, Katie E Keenoy, J Philip Miller, Elaine H Morrato, Zhaohua Guo, Bradley A Evanoff, Joseph J Parks, and John W Newcomer

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Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer, Thanh Nguyen, Dhivya Sridaran, Surbhi Chouhan, Cody Weimholt, Audrey Wilson, Jingqin Luo, Tiandao Li, John Koomen, Bin Fang, Nagireddy Putluri, Arun Sreekumar, Felix Y Feng, Kiran Mahajan, and Nupam P Mahajan

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The child's age and the size of the curvature do not affect the accuracy of screw placement with the free-hand technique in spinal deformities in children and adolescents, Pawel Grabala, Ilkka J Helenius, Piotr Kowalski, Michal Grabala, Slawomir Zacha, Jaroslaw M Deszczynski, Tomasz Albrewczynski, Michael A Galgano, Jacob M Buchowski, Kelly Chamberlin, and Suken A Shah

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Zinc cluster transcription factors frequently activate target genes using a non-canonical half-site binding mode, Pamela S Recio, Nikhil J Mitra, Christian A Shively, David Song, Grace Jaramillo, Kristine Shady Lewis, Xuhua Chen, and Robi D Mitra

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Dostarlimab for primary advanced or recurrent endometrial cancer, Mansoor R Mirza, Carolyn McCourt, Matthew A Powell, and et al.

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Guidance on the use of convalescent plasma to treat immunocompromised patients with coronavirus disease 2019, Evan M Bloch, Jeffrey P Henderson, Brenda J Grossman, and et al.

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Pembrolizumab plus chemotherapy in advanced endometrial cancer, Ramez N Eskander, Premal H Thaker, Matthew A Powell, and et al.

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The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes, Amjad Horani, Deepesh Kumar Gupta, Jian Xu, Huihui Xu, Lis Del Carmen Puga-Molina, Celia M. Santi, Sruthi Ramagiri, Steven K. Brennan, Jiehong Pan, Jeffrey R. Koenitzer, Tao Huang, Rachael M. Hyland, Sean P. Gunsten, Shin-Cheng Tzeng, Jennifer M. Strahle, Pleasantine Mill, Moe R. Mahjoub, Susan K Dutcher, and Steven L Brody

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Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS, Conor McClenaghan, Maya A Mukadam, Jacob Roeglin, Robert C Tryon, Manfred Grabner, Anamika Dayal, Gretchen A Meyer, and Colin G Nichols

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Standardized immunoprecipitation protocol for efficient isolation of native apolipoprotein E particles utilizing HJ15.4 monoclonal antibody, Justin O'Leary, Ana-Caroline Raulin, Zonghua Li, Yuka Martens, Yasuteru Inoue, Michael R Strickland, Xianlin Han, David M Holtzman, Guojun Bu, and Na Zhao

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Validation of the adolescent binge eating disorder measure (ADO-BED) among transgender youth and young adults, Whitney Linsenmeyer, Dana Stiles, Sarah Garwood, Andrea Giedinghagen, Christopher Lewis, and Gretta Strand

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Brain abscess and stroke in children and adults with hereditary hemorrhagic telangiectasia: Analysis of a large national claims database, Andrew J. White, Itay Marmor, Kate M. Peacock, Katelin B. Nickel, Jessica Zavadil, and Margaret A. Olsen

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Inequities in treatments and outcomes among patients hospitalized with hypertrophic cardiomyopathy in the United States, Daniel Y Johnson, R J Waken, Daniel K Fox, Gmerice Hammond, Karen E Joynt Maddox, and Sharon Cresci

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Novel vaccine against pathological pyroglutamate-modified amyloid beta for prevention of Alzheimer's disease, Karen Zagorski, Olga King, Armine Hovakimyan, Irina Petrushina, Tatevik Antonyan, Gor Chailyan, Manush Ghazaryan, Krzysztof L Hyrc, Jean Paul Chadarevian, Hayk Davtyan, Mathew Blurton-Jones, David H Cribbs, Michael G Agadjanyan, and Anahit Ghochikyan

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Peptidoglycan deacetylation controls type IV secretion and the intracellular survival of the bacterial pathogen Legionella pneumophila, David Boamah, Michael C Gilmore, Sarah Bourget, Anushka Ghosh, Mohammad J Hossain, Joseph P Vogel, Felipe Cava, and Tamara J O'Connor