Submissions from 2023
Toward blood-based precision medicine: Identifying age-sex-specific vascular biomarker quantities on circulating vascular cells, Yingye Fang, Ling Chen, and P I Imoukhuede
Transcription regulation by CarD in mycobacteria is guided by basal promoter kinetics, Dennis X Zhu and Christina L Stallings
Uridine-derived ribose fuels glucose-restricted pancreatic cancer, Zeribe C Nwosu, Matthew H Ward, Leah P Shriver, Gary J Patti, and et al.
Healthcare provider perspectives on HIV cure research in Ghana, Helena Lamptey, Benjamin Newcomb, Evelyn Y Bonney, James O Aboagye, Peter Puplampu, Vincent J Ganu, Gloria Ansa, Joseph Oliver-Commey, and George B Kyei
Irritability moderates the association between cognitive flexibility task performance and related prefrontal cortex activation in young children, Yanwei Li, Adam S Grabell, and Susan B Perlman
Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation, Simona Pagliuca, Francesca Ferraro, and et al.
Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling, Rafaela M Guimarães, Conceição E Aníbal-Silva, Marcela Davoli-Ferreira, Francisco Isaac F Gomes, Atlante Mendes, Maria C M Cavallini, Miriam M Fonseca, Samara Damasceno, Larissa P Andrade, Marco Colonna, Cyril Rivat, Fernando Q Cunha, José C Alves-Filho, and Thiago M Cunha
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells, Weiwei Xu, Wandy Beatty, and et al.
Reliability of MRI interpretation of Discoid Lateral Meniscus: A multicenter study, Emily L. Niu, Matthew D. Milewski, Craig J. Finlayson, Zachary S. Stinson, Elaine Joughin, Jeffrey J. Nepple, Gregory A. Schmale, PRiSM Meniscus Research Interest Group, and Jennifer Beck
Resting-state cortical hubs in youth organize into four categories, Damion V Demeter, Evan M Gordon, Tehila Nugiel, AnnaCarolina Garza, Tyler L Larguinho, and Jessica A Church
Scanning electron microscopy of human islet cilia, Alexander J Polino, Sanja Sviben, Isabella Melena, David W Piston, and Jing W Hughes
Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation, Yunlong Li, Soneya Majumdar, Ryan Treen, Manjuli R Sharma, Jamie Corro, Howard B Gamper, Swati R Manjari, Jerome Prusa, Nilesh K Banavali, Christina L Stallings, Ya-Ming Hou, Rajendra K Agrawal, and Anil K Ojha
Peptide-based nanoparticles for systemic extrahepatic delivery of therapeutic nucleotides, Samuel A Wickline, Kirk K Hou, and Hua Pan
Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: A multinational embedded cluster crossover randomized trial (the HIKO STEC trial), Stephen B Freedman, David Schnadower, Myka Estes, T Charles Casper, Stuart L Goldstein, Silviu Grisaru, Andrew T Pavia, Benjamin S Wilfond, Melissa Metheney, Kadyn Kimball, Phillip I Tarr, and Hyperhydration to Improve Kidney Outcomes in children with Shiga Toxin-producing E. Coli infection (HIKO-STEC) Study Team
Evaluation of pitting corrosion by dynamic speckle pattern analysis, Omid Pedram, Ramin Jamali, Vahid Abbasian, Vahideh Farzam Rad, Arash Darafsheh, Ramin Khamedi, Esmaeil Poursaeidi, and Ali-Reza Moradi
Team-focused implementation strategies to improve implementation of mental health screening and referral in rural Children's Advocacy Centers: Study protocol for a pilot cluster randomized hybrid type 2 trial, Elizabeth A McGuier, Gregory A Aarons, Jaely D Wright, John C Fortney, Byron J Powell, Scott D Rothenberger, Laurie R Weingart, Elizabeth Miller, and David J Kolko
Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound, Yaoheng Yang, Jinyun Yuan, Rachael L Field, Dezhuang Ye, Zhongtao Hu, Kevin Xu, Lu Xu, Yan Gong, Yimei Yue, Alexxai V Kravitz, Michael R Bruchas, Jianmin Cui, Jonathan R Brestoff, and Hong Chen
Tau accumulation in autosomal dominant Alzheimer's disease: A longitudinal [18F]flortaucipir study, Antoinette O'Connor, Shaney Flores, Russ Hornbeck, Eric McDade, Brian A Gordon, Randall J Bateman, Tammie L S Benzinger, and et al.
Mechanically manipulating glymphatic transport by ultrasound combined with microbubbles, Dezhuang Ye, Si Chen, Yajie Liu, Charlotte Weixel, Zhongtao Hu, Jinyun Yuan, and Hong Chen
Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state, Shuang Li, Jie Sun, Shixuan Liu, Fengbo Zhou, Michael L Gross, and Weikai Li
Pilot study on the influence of incentive spirometry on percutaneous image-guided intra-abdominal drainage catheter pressure: A potential method to enhance drainage, Aravinda Ganapathy, David H. Ballard, Grace L. Bishop, Mark J. Hoegger, Nihil Abraham, and Horacio B. D'Agostino
Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression, Anish Mitra, Marcus E Raichle, Andrew D Geoly, Ian H Kratter, and Nolan R Williams
Upregulation of the Oct3/4 network in basal breast cancer is associated with its metastatic potential and shows tissue dependent variability, Robin G Rajan, Raisa I Krutilina, Tatyana N Ignatova, Zoran S Pavicevich, Galina M Dulatova, Maria A Lane, Arindam R Chatterjee, Robert J Rooney, Mymoon Antony, Vivian R Hagerty, Nickolay V Kukekov, Khalid A Hanafy, and Frank D Vrionis
Protocol to isolate RBP-mRNA complexes using RNA-CLIP and examine target mRNAs, Valerie Blanc, Elizabeth A Molitor, and Nicholas O Davidson
Smoking status, nicotine medication, vaccination, and COVID-19 hospital outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) study, Thomas M Piasecki, Li-Shiun Chen, and et al.
Integrating tobacco treatment into oncology care: Reach and effectiveness of evidence-based tobacco treatment across National Cancer Institute-designated cancer centers, Sarah D Hohl, Alex T Ramsey, Li-Shiun Chen, and et al.
Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome, Tomeka L Suber, Stacy G Wendell, Steven J Mullett, Benjamin Zuchelkowski, William Bain, Georgios D Kitsios, Bryan J McVerry, Prabir Ray, Anuradha Ray, Rama K Mallampalli, Yingze Zhang, Faraaz Shah, Seyed Mehdi Nouraie, and Janet S Lee
Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release, Mustafa Balkaya, Preeti Dohare, Sophie Chen, Alexandra L Schober, Antonio M Fidaleo, Julia W Nalwalk, Rajan Sah, and Alexander A Mongin
Multi-stakeholder perspectives regarding preferred modalities for mental health intervention delivered in the orthopedic clinic: A qualitative analysis, Abby L Cheng, Ashwin J Leo, Ryan P Calfee, Christopher J Dy, Melissa A Armbrecht, and Joanna Abraham
Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem, Michaela Schwaiger-Haber, Ethan Stancliffe, Dhanalakshmi S Anbukumar, Blake Sells, Jia Yi, Kevin Cho, Kayla Adkins-Travis, Milan G Chheda, Leah P Shriver, and Gary J Patti
Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma, Claire Roddie, Nancy Bartlett, and et al.
Predicting alcohol-related memory problems in older adults: A machine learning study with multi-domain features, Chella Kamarajan, Andrey P Anokhin, Sarah Hartz, Laura J Bierut, Vivia V McCutcheon, Kathleen K Bucholz, and Et al.
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreatic adenocarcinoma: A phase 1b observational study, Lauren K Park, Kian-Huat Lim, Jonas Volkman, Mina Abdiannia, Hannah Johnston, Zack Nigogosyan, Marilyn J Siegel, Janet B McGill, Alexis M McKee, Maamoun Salam, Rong M Zhang, Da Ma, Karteek Popuri, Vincent Tze Yang Chow, Mirza Faisal Beg, William G Hawkins, Linda R Peterson, and Joseph E Ippolito
Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus, Cameron Sadegh, Yong Zhang, Michael J Holtzman, and et al.
The evolution of primary care telehealth disparities during COVID-19: Retrospective cohort study, Rachel D'Amico, Patrick M Schnell, Randi Foraker, J Nwando Olayiwola, Daniel E Jonas, and Seuli Bose Brill
A single-cell multiomic analysis of kidney organoid differentiation, Yasuhiro Yoshimura, Yoshiharu Muto, Nicolas Ledru, Haojia Wu, Kohei Omachi, Jeffrey H Miner, and Benjamin D Humphreys
Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes, Celia A McKee, Alexander J Polino, Melvin W King, and Erik S Musiek
Genome-wide association study of breast density among women of African ancestry, Shefali Setia Verma, Lindsay Guare, Sarah Ehsan, Aimilia Gastounioti, Gabrielle Scales, Marylyn D Ritchie, Despina Kontos, Anne Marie McCarthy, and Penn Medicine Biobank
How does facilitation in healthcare work? Using mechanism mapping to illuminate the black box of a meta-implementation strategy, Amy M Kilbourne, Elvin Geng, Ingrid Eshun-Wilson, Shannon Sweeney, Donna Shelley, Deborah J Cohen, JoAnn E Kirchner, Maria E Fernandez, and Michael L Parchman
Biomechanical models and mechanisms of cellular morphogenesis and cerebral cortical expansion and folding, David C Van Essen
Cortical atrophy and leukoaraiosis, imaging markers of cerebrovascular small vessel disease, are associated with driving behavior changes among cognitively normal older adults, Ganesh M Babulal, Ling Chen, David B Carr, Ann M Johnson, Joshua S Shimony, Jason Doherty, Samantha Murphy, Alexis Walker, Hailee Domash, Russ Hornbeck, Sarah Keefe, Shaney Flores, Cyrus A Raji, John C Morris, Beau M Ances, and Tammie L S Benzinger
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy, Alan J. Russell, Twlya I. Juehne, Jinsheng Yu, and et al.
Safety and efficacy of axicabtagene ciloleucel versus standard of care in patients 65 years of age or older with relapsed/refractory large B-cell lymphoma, Jason R Westin, Armin Ghobadi, and et al.
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification, Punn Augsornworawat, Nathaniel J Hogrebe, Matthew Ishahak, Mason D Schmidt, Erica Marquez, Marlie M Maestas, Daniel A Veronese-Paniagua, Sarah E Gale, Julia R Miller, Leonardo Velazco-Cruz, and Jeffrey R Millman
Strategies to bridge equitable implementation of telehealth, Allison M Gustavson, Allison A Lewinski, Ellen E Fitzsimmons-Craft, Gloria D Coronado, Sarah E Linke, Denalee M O'Malley, Alyce S Adams, Russell E Glasgow, and Lisa M Klesges
Role of midkine in cancer drug resistance: Regulators of its expression and its molecular targeting, Minakshi Saikia, Nathan Cheung, Abhay Kumar Singh, and Vaishali Kapoor
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter, Kelsie M LaBarbera, Carla M Yuede, Hannah M Edwards, Woodrow D Gardiner, John R Cirrito, and et al.
Effects of a virtual voice-based coach delivering problem-solving treatment on emotional distress and brain function: A pilot RCT in depression and anxiety, Thomas Kannampallil and et al.
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma, Rui Sun, Rowland Han, Colin McCornack, Saad Khan, G Travis Tabor, Yun Chen, Jinchao Hou, Haowu Jiang, Kathleen M Schoch, Diane D Mao, Ryan Cleary, Alicia Yang, Qin Liu, Jingqin Luo, Allegra Petti, Timothy M Miller, Jason D Ulrich, David M Holtzman, and Albert H Kim
Co-clinical imaging metadata information (CIMI) for cancer research to promote open science, standardization, and reproducibility in preclinical imaging, Stephen M Moore, James D Quirk, Andrew W Lassiter, Richard Laforest, Kooresh I Shoghi, and et al.
Data envelopment analysis to evaluate the efficiency of tobacco treatment programs in the NCI Moonshot Cancer Center Cessation Initiative, Kathryn Pluta, Li-Shiun Chen, and et al.
Five-year follow-up of ZUMA-1 supports the curative potential of axicabtagene ciloleucel in refractory large B-cell lymphoma, Sattva S Neelapu, Armin Ghobadi, Nancy L Bartlett, and et al.
Protocol for a scoping review of health equity frameworks and models applied in empirical studies of chronic disease prevention and control, Callie Walsh-Bailey, Amanda Gilbert, Thembekile Shato, Brittney Sandler, Ana A Baumann, Cory D Bradley, Gabriella M McLoughlin, F Hunter McGuire, Meredith P Fort, and Rachel G Tabak
Two forms of asynchronous release with distinctive spatiotemporal dynamics in central synapses, Gerardo Malagon, Jongyun Myeong, and Vitaly A Klyachko
Bronchoscopic evaluation of a steerable needle for simulated tumor targets in the lung periphery: A feasibility study (Bullseye), Alexander C. Chen, Michael Machuzak, George Cheng, and Momen M. Wahidi
Diagnosis and treatment of fungal infections in lung transplant recipients, Jesus E Escamilla, Spenser E January, and Rodrigo Vazquez Guillamet
Dynamic frailty risk assessment among older adults with multiple myeloma: A population-based cohort study, Hira Mian, Tanya M Wildes, Ravi Vij, Matthew J Pianko, Ajay Major, and Mark A Fiala
Study design and protocol of a stepped wedge cluster randomized trial using a practical implementation strategy as a model for hypertension-HIV integration - The MAP-IT trial, Angela A Aifah, Daphne Lew, and et al.
Layperson perception of reflux-related symptoms, Jakob L. Fischer, Anthony M. Tolisano, Alvaro I. Navarro, Lily Trinh, Waleed M. Abuzeid, Ian M. Humphreys, Nadeem A. Akbar, Sharan Shah, John S. Schneider, Charles A. Riley, and Edward D. McCoul
T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity, Conor M. Finlay, Gwendalyn J. Randolph, and et al.
Impact of early relapse within 24 months after first-line systemic therapy (POD24) on outcomes in patients with marginal zone lymphoma: A US multisite study, Narendranath Epperla, Lauren Shea, Nancy L Bartlett, and et al.
Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1, Claire A. Ruddiman, Richard Peckham, Melissa A. Luse, Yen-Lin Chen, Maniselvan Kuppusamy, Bruce A. Corliss, P. Jordan Hall, Chien-Jung Lin, Shayn M. Peirce, Swapnil K. Sonkusare, Robert P. Mecham, Jessica E. Wagenseil, and Brant E. Isakson
RBM47 regulates intestinal injury and tumorigenesis by modifying proliferation, oxidative response, and inflammatory pathways, Saeed Soleymanjahi, Valerie Blanc, Elizabeth A. Molitor, David M. Alvarado, Yan Xie, Vered Gazit, Jeffrey W. Brown, Kathleen Byrnes, Ta-Chiang Liu, Jason C. Mills, Matthew A. Ciorba, Deborah C. Rubin, and Nicholas O. Davidson
Protocol for tumor dissociation and fluorescence-activated cell sorting of human head and neck cancers, Ogoegbunam Okolo, Victoria Yu, Samuel Flashner, Cecilia Martin, Hiroshi Nakagawa, Derrick T Lin, Sidharth V Puram, and Anuraag S Parikh
A retrospective multi-institutional cohort analysis of clinical characteristics and outcomes in dedifferentiated chondrosarcoma, Nam Bui, Hilary Dietz, Sheima Farag, Angela C Hirbe, Michael J Wagner, Brian A Van Tine, Kristen Ganjoo, Robin L Jones, Vicki L Keedy, and Elizabeth J Davis
Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes, Nathaniel J Hogrebe, Matthew Ishahak, and Jeffrey R Millman
Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis, Amy M Peiper, Emily W Helm, Quyen Nguyen, Matthew Phillips, Caroline G Williams, Dhairya Shah, Sarah Tatum, Neha Iyer, Marco Grodzki, Laura B Eurell, Aqsa Nasir, Megan T Baldridge, and Stephanie M Karst
Organizational readiness to implement task-strengthening strategy for hypertension management among people living with HIV in Nigeria, Juliet Iwelunmor, Daphne Lew, and et al.
Associations between cannabis use, polygenic liability for schizophrenia, and cannabis-related experiences in a sample of cannabis users, Emma C Johnson, Sarah M C Colbert, Paul W Jeffries, Rebecca Tillman, Nicole R Karcher, Elliot C Nelson, Arpana Agrawal, and et al.
KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease-related pathology, John Grizzanti, William R. Moritz, Molly Stanley, Emily E. Caesar, Maria S. Remedi, Celeste M. Karch, Colin G. Nichols, David M. Holtzman, and et al.
State-level macro-economic factors moderate the association of low income with brain structure and mental health in U.S. children, David G Weissman, Mark L Hatzenbuehler, Mina Cikara, Deanna M Barch, and Katie A McLaughlin
Whole-exome sequencing prioritizes candidate genes for hereditary cataract in the Emory mouse mutant, Thomas M Bennett, Yuefang Zhou, Kacie J Meyer, Michael G Anderson, and Alan Shiels
A draft human pangenome reference, Wen-Wei Liao, Haley J Abel, Robert S Fulton, Chad Tomlinson, Lucinda L Antonacci-Fulton, Sarah Cody, Allison A Regier, Ting Wang, and et al.
A phase 1 first-in-human study of GS-0189, an anti-signal regulatory protein alpha (SIRPα) monoclonal antibody, in patients with relapsed/refractory (R/R) non-Hodgkin lymphoma (NHL), Mayur Narkhede, Nancy L Bartlett, Sami Ibrahimi, Leslie Popplewell, Anna Seto, Jamie Bates, Yeonju Lee, Vaishnavi Ganti, Ling Han, Tianling Chen, and Manish R Patel
A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis, Nicholas O. Opoku, Nicole Fetcho, Kerstin Fischer, Peter U. Fischer, Charles W. Goss, Augustine R. Hong, Daphne Lew, Gary J. Weil, and et al.
Association of sex with neurobehavioral markers of executive function in 2-year-olds at high and low likelihood of autism, Tanya St John, Natasha Marrus, Kelly N Botteron, and et al.
Belimumab versus anifrolumab in adults with systemic lupus erythematosus: An indirect comparison of clinical response at 52 weeks, Binod Neupane, Pragya Shukla, Mahmoud Slim, Amber Martin, Michelle Petri, George K. Bertsias, Alfred H J Kim, Antonis Fanouriakis, Roger A. Levy, Deven Chauhan, and Nick Ballew
BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy, Yanyan Geng, Ping Li, Alice Butler, Bill Wang, Lawrence Salkoff, and Karl L Magleby
Blockade of TRPV channels by intracellular spermine, Grigory Maksaev, Peng Yuan, and Colin G Nichols
Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae, Paeton L. Wantuch, Cory J. Knoot, Lloyd S. Robinson, Evgeny Vinogradov, Nichollas E. Scott, Christian M. Harding, and David A. Rosen
Chemotherapy-induced toxicities: An imaging primer, Nikhil S. Patil, Natasha Larocque, Christian B. van der Pol, Carlos Torres, Demetrios A. Raptis, and Michael N. Patlas
Circulating markers of microbial translocation and host response to bacteria with risk of colorectal cancer: A prospective, nested case-control study in men, Mengyao Shi, Xiaoyu Zong, Jinhee Hur, Brenda M Birmann, Otoniel Martinez-Maza, Marta Epeldegui, Andrew T Chan, Edward L Giovannucci, and Yin Cao
Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes, Simona Ghetti, Kimberly S Quayle, and et al.
Comparing genomic and epigenomic features across species using the WashU Comparative Epigenome Browser, Xiaoyu Zhuo, Silas Hsu, Deepak Purushotham, Prashant Kumar Kuntala, Jessica K Harrison, Alan Y Du, Samuel Chen, Daofeng Li, and Ting Wang
Deep learning based on co-registered ultrasound and photoacoustic imaging improves the assessment of rectal cancer treatment response, Yixiao Lin, Sitai Kou, Haolin Nie, Hongbo Luo, Ahmed Eltahir, Will Chapman Jr., Steven Hunt, Matthew Mutch, and Quing Zhu
Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors, Paweorn Angsutararux, Amal K Dutta, Martina Marras, Carlota Abella, Rebecca L Mellor, Jingyi Shi, Jeanne M Nerbonne, and Jonathan R Silva
Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b, Lindsey A Lee, Samantha K Barrick, Ada E Buvoli, Jonathan Walklate, W Tom Stump, Michael Geeves, Michael J Greenberg, and Leslie A Leinwand
Effect of P2Y12 inhibitors on organ support-free survival in critically ill patients hospitalized for COVID-19: A randomized clinical trial, Jeffrey S Berger, Grant V Bochicchio, and et al.
Effect of trainee level on surgical time and postoperative complications of anterior cruciate ligament reconstruction, Priyanka Parameswaran, Yash Tarkunde, J. Sam Broughton, Michael G. Rizzo, Jake H. Goldfarb, and Robert H. Brophy
Effects of a combination economic empowerment and family strengthening intervention on psychosocial well-being among Ugandan adolescent girls and young women: Analysis of a cluster randomized controlled trial (Suubi4Her), Lindsey M Filiatreau, Nhial Tutlam, Rachel Brathwaite, William Byansi, Flavia Namuwonge, Abel Mwebembezi, Ozge Sensoy-Bahar, Proscovia Nabunya, Torsten B Neilands, Patricia Cavazos-Rehg, Mary McKay, and Fred M Ssewamala
Examining mental health, education, employment, and pain in sickle cell disease, Kelly M Harris, Liliana Preiss, Taniya Varughese, Anna Bauer, Cecelia L Calhoun, Marsha Treadwell, Rita Masese, Jane S Hankins, Faiz Ahmed Hussain, Jeffrey Glassberg, Cathy L Melvin, Robert Gibson, Allison A King, and Sickle Cell Disease Implementation Consortium
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway, Alexander D Fulford, Leonie Enderle, Jannette Rusch, Didier Hodzic, Maxine V Holder, Alex Earl, Robin Hyunseo Oh, Nicolas Tapon, and Helen McNeill
First-in-human phase Ib trial of M9241 (NHS-IL12) plus avelumab in patients with advanced solid tumors, including dose expansion in patients with advanced urothelial carcinoma, Julius Strauss, Russell K. Pachynski, and et al.
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity, Meigen Yu, Hui Ye, Ruth B. De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V. Lee, Yarong Li, Duc Duong, Bridget Phillips, Carlos Cruchaga, Genevera I. Allen, Nicholas T. Seyfried, Ismael Al-Ramahi, Juan Botas, and Joshua M. Shulman
Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer, Andrew A Davis, Jingqin Luo, Rama Suresh, Foluso O Ademuyiwa, Caron Rigden, Timothy P Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Tracy Summa, Brittney Haas, Shana Thomas, Leonel F Hernandez-Aya, Lindsay L Peterson, Cynthia X Ma, and et al.
Gluteus maximus transfer for hip abductor deficiency, Paul M Inclan, Maria T Schwabe, Bryant M Song, Andrew W Kuhn, Daniel R Layon, John C Clohisy, and Cecilia Pascual-Garrido
Identifying regions of interest in mammogram images, Shu Jiang, Jiguo Cao, and Graham A. Colditz
Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice, Niraj Shrestha, Mark Foster, Lynne Marsala, Pamela Wong, Celia C Cubitt, Jennifer A Foltz, Jennifer Tran, Timothy Schappe, Melissa M Berrien-Elliott, Todd A Fehniger, and et al.
Independent study demonstrates amyloid probability score accurately indicates amyloid pathology, Ilana Fogelman, Randall J Bateman, David M Holtzman, and et al.
Influence of genomic landscape on cancer immunotherapy for newly diagnosed ovarian cancer: Biomarker analyses from the IMagyn050 randomized clinical trial, Charles N Landen, Premal H Thaker, and et al.
