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Submissions from 2024

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MS treatment de-escalation: Review and commentary, Krzysztof Selmaj, Hans-Peter Hartung, Marcin P Mycko, Igor Selmaj, and Anne H Cross

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Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates, Matthew Gagne, James Brett Case, Igor P Dmitriev, Elena A Kashentseva, Baoling Ying, David T Curiel, Michael S Diamond, and et al.

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Multi-site EEG studies in early infancy: Methods to enhance data quality, Abigail Dickinson, John Zempel, Natasha Marrus, John R Pruett Jr, and et al.

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Network-level enrichment provides a framework for biological interpretation of machine learning results, Jiaqi Li, Ari Segel, Xinyang Feng, Jiaxin Cindy Tu, Andy Eck, Kelsey T King, Babatunde Adeyemo, Nicole R Karcher, Likai Chen, Adam T Eggebrecht, and Muriah D Wheelock

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Network-level enrichment provides a framework for biological interpretation of machine learning results, Jiaqi Li, Ari Segel, Xinyang Feng, Jiaxin Cindy Tu, Andy Eck, Kelsey T King, Babatunde Adeyemo, Nicole R Karcher, Likai Chen, Adam T Eggebrecht, and Muriah D Wheelock

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New insights into innate immunity in Alzheimer's disease: From APOE protective variants to therapies, Yun Chen and David M Holtzman

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Perioperative antibiotic prophylaxis duration in patients undergoing cystectomy with urinary diversion: A randomized clinical trial, Maria C Thurnheer, Astrid Schürmann, Markus Huber, Jonas Marschall, Patrick Y Wuethrich, and Fiona C Burkhard

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PKMYT1 is a marker of treatment response and a therapeutic target for CDK4/6 inhibitor-resistance in ER+ breast cancer, Anran Chen, Cynthia X Ma, and et al.

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Postprostatectomy radiotherapy timing and long-term health-related quality of life, Sagar A Patel, Jeff M Michalski, and et al.

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Post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis attenuates disparity in outcomes between use of matched or mismatched unrelated donors, Brian C Shaffer, Ramzi Abboud, and et al.

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Prophylactic antibiotics for excision of premalignant vulvar lesions: A pilot randomized controlled trial, Mary M Mullen, Whitney R Grither, Hannah Millimet, David G Mutch, Andrea R Hagemann, Carolyn K McCourt, Matthew A Powell, Premal H Thaker, Dineo Khabele, and Lindsay M Kuroki

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Proteome-wide genetic investigation of large artery stiffness, Marie-Joe Dib, Ali Javaheri, Douglas L Mann, and et al.

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Rehabilitation transition program to improve community participation among stroke survivors: A randomized clinical trial, Rebecca M Bollinger, Melissa J Krauss, Emily K Somerville, Brianna M Holden, Gabrielle Blenden, Holly Hollingsworth, Audrey A Keleman, Alexandre Carter, Timothy D McBride, Abigail R Barker, Yan Yan, and Susan L Stark

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Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination, Yuhao Li, Jerome M. Molleston, Crystal Lovato, Jasmine Wright, Isabel Erickson, Duyen Bui, Andrew H. Kim, Harshad Ingle, Somya Aggarwal, Lila S Nolan, Ahmed O. Hassan, Lynne Foster, Michael S. Diamond, and Megan T. Baldridge

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Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili, Ryan M Bitter, Maxwell I Zimmerman, Brock T Summers, Jerome S Pinkner, Karen W Dodson, Scott J Hultgren, and Peng Yuan

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The Dallas Donation after Circulatory Death Transplantation Summit: expanding donation after circulatory death procedures through process improvement, broader utilization, and innovation, Michele Finotti, William C. Chapman, and et al.

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Three- and seven-month prostate-specific antigen levels as prognostic markers for overall survival in metastatic hormone-sensitive prostate cancer: Results from SWOG S1216, a phase 3 randomized trial of androgen deprivation plus orteronel or bicalutamide, Mamta Parikh, Russell K Pachynski, and et al.

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Three classes of propofol binding sites on GABAA receptors, Zi-Wei Chen, Satyanarayana M Chintala, John Bracamontes, Yusuke Sugasawa, Spencer R Pierce, Balazs R Varga, Edward H Smith, Christopher J Edge, Nicholas P Franks, Wayland W L Cheng, Gustav Akk, and Alex S Evers

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Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses, Sumanta K Naik, Michael E McNehlan, Yassin Mreyoud, Rachel L Kinsella, Asya Smirnov, Chanchal Sur Chowdhury, Samuel R McKee, Neha Dubey, Reilly Woodson, Darren Kreamalmeyer, and Christina L Stallings

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Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway, Chen-Ting Hung, Changqing Ma, Santosh K Panda, Tihana Trsan, Miki Hodel, Jennifer Frein, Amanda Foster, Shengxiang Sun, Hung-Ting Wu, Justin Kern, Richa Mishra, Umang Jain, Marco Colonna, Ta-Chiang Liu, and et al.

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Assessing the response results of an mHealth-based patient experience survey among people receiving HIV care in Lusaka, Zambia: Cohort study, Jacob Mutale, Kombatende Sikombe, Boroma Mwale, Mwansa Lumpa, Sandra Simbeza, Chama Bukankala, Njekwa Mukamba, Aaloke Mody, Laura K Beres, Charles B Holmes, Carolyn Bolton Moore, Elvin H Geng, Izukanji Sikazwe, and Jake M Pry

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Negative effect of treatment with mGluR5 negative allosteric modulator AFQ056 on blood biomarkers in young individuals with Fragile X syndrome, Dragana Protic, Stephanie Morris, and et al.

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A multicenter, randomized, non-comparative, phase II study of nivolumab ± ipilimumab for patients with metastatic sarcoma (Alliance A091401): Expansion cohorts and correlative analyses, Nathan D Seligson, James L Chen, Austin C Goodrich, Brian A Van Tine, Jordan D Campbell, Allison L Richards, Cristina R Antonescu, David A Liebner, Mohammed M Milhem, Howard Streicher, William D Tap, Gary K Schwartz, Suzanne George, and Sandra P D'Angelo

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Inorganic polyphosphate promotes colorectal cancer growth via TRPM8 receptor signaling pathway, Valentina Arrè, Chen Shen, and et al.

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Safety of dostarlimab in combination with chemotherapy in patients with primary advanced or recurrent endometrial cancer in a phase III, randomized, placebo-controlled trial (ENGOT-EN6-NSGO/GOG-3031/RUBY), Annika Auranen, Matthew A Powell, and et al.

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A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models, Maritza Puray-Chavez, Jenna E Eschbach, Ming Xia, Kyle M LaPak, Qianzi Zhou, Ria Jasuja, Jiehong Pan, Jian Xu, Zixiang Zhou, Shawn Mohammed, Qibo Wang, Dana Q Lawson, Sanja Djokic, Gaopeng Hou, Siyuan Ding, Steven L Brody, Michael B Major, Dennis Goldfarb, and Sebla B Kutluay

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Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire, Hao Hu, Anthony N Vomund, Orion J Peterson, Neetu Srivastava, Tiandao Li, Lisa Kain, Wandy L Beatty, Bo Zhang, Chyi-Song Hsieh, Luc Teyton, Cheryl F Lichti, Emil R Unanue, and Xiaoxiao Wan

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Length-scale study in deep learning prediction for non-small cell lung cancer brain metastasis, Haowen Zhou, Siyu Lin, Mark Watson, Cory T Bernadt, Oumeng Zhang, Ling Liao, Ramaswamy Govindan, Richard J Cote, and Changhuei Yang

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Massively parallel characterization of insulator activity across the genome, Clarice K Y Hong, Yawei Wu, Alyssa A Erickson, Jie Li, Arnold J Federico, and Barak A Cohen

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Nur77 protects the bladder urothelium from intracellular bacterial infection, Christina A Collins, Chevaughn Waller, Ekaterina Batourina, Lokesh Kumar, Cathy L Mendelsohn, and Nicole M Gilbert

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Durations of antibiotic treatment for acute otitis media and variability in prescribed durations across two large academic health systems, Sophie E Katz, Timothy C Jenkins, Amy B Stein, Gale Thomas, Nancy Koenig, Gary Lucas Starnes, Jason G Newland, Ritu Banerjee, and Holly M Frost

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Treatment outcomes among patients with a positive Candida culture close to randomization receiving rezafungin or caspofungin in the ReSTORE study, Alex Soriano, Marin Kollef, and et al.

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Evaluating generative AI's ability to identify cancer subtypes in publicly available structured genetic datasets, Ethan Hillis, Kriti Bhattarai, and Zachary Abrams

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Conformational ensembles in Klebsiella pneumoniae FimH impact uropathogenesis, Edward D B Lopatto, Jerome S Pinkner, Denise A Sanick, Robert F Potter, Lily X Liu, Jesús Bazán Villicaña, Kevin O Tamadonfar, Yijun Ye, Maxwell I Zimmerman, Nathaniel C Gualberto, Karen W Dodson, James W Janetka, David A Hunstad, and Scott J Hultgren

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Evaluating the impact of a year-long external mentorship pilot program in classical hematology, Zoya Qureshy, Pooja Nair, Sara K Vesely, Allison A King, Alfred I Lee, Nathan T Connell, Annette von Drygalski, Ida Wong-Sefidan, Martina C Murphy, Ronak H Mistry, Rebecca L Zon, Erin G Reid, Josel Fritz, and Soo J Park

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Intracranial aneurysms in sickle cell disease are associated with hemodynamic stress and anemia, Yan Wang, Jared S Garland, Slim Fellah, Martin N Reis, Matthew S Parsons, Kristin P Guilliams, Melanie E Fields, Amy E Mirro, Josiah B Lewis, Chunwei Ying, Rachel A Cohen, Monica L Hulbert, Allison A King, Yasheng Chen, Jin-Moo Lee, Hongyu An, and Andria L Ford

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Spatiotemporal relationships between neuronal, metabolic, and hemodynamic signals in the awake and anesthetized mouse brain, Xiaodan Wang, Jonah A Padawer-Curry, Annie R Bice, Byungchan Kim, Zachary P Rosenthal, Jin-Moo Lee, Manu S Goyal, Shannon L Macauley, and Adam Q Bauer

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The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS, Sapana Bansod, Paarth B Dodhiawala, Yutong Geng, Ashenafi Bulle, Peng Liu, Lin Li, Reid Townsend, Patrick M Grierson, Jason M Held, Hema Adhikari, and Kian-Huat Lim

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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells, Tihana Trsan, Vincent Peng, Takahiro E Ohara, Wandy L Beatty, Raki Sudan, Praveen Krishnamoorthy, Patrick Fernandes Rodrigues, Jose L Fachi, Gary Grajales-Reyes, Natalia Jaeger, James A J Fitzpatrick, Marina Cella, Susan Gilfillan, Marco Colonna, and et al.

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CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET, Kwangsik Nho, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, and et al.

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Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models, Václav Havel, Amanda Hunkele, Rohini S Ople, Susruta Majumdar, and et al.

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Protocol for continuous intravenous drug delivery with implantable iPrecio pump in free-moving rats and mice, Tusar Giri and Arvind Palanisamy

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Protocol for multimodal profiling of human kidneys with simultaneous high-throughput ATAC and RNA expression with sequencing, Haikuo Li and Benjamin D Humphreys

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STARDUST: A pipeline for the unbiased analysis of astrocyte regional calcium dynamics, Yifan Wu, Yanchao Dai, Katheryn B Lefton, Timothy E Holy, and Thomas Papouin

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Axatilimab in recurrent or refractory chronic graft-versus-host disease, Daniel Wolff, Iskra Pusic, and et al.

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Randomized phase III SIERRA trial of 131I-apamistamab before allogeneic hematopoietic cell transplantation versus conventional care for relapsed/refractory AML, Boglarka Gyurkocza, Camille Abboud, and et al.

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Treatment resistance to melanoma therapeutics on a single cell level, Lijun Yao, Bradley A Krasnick, Ye Bi, Sunantha Sethuraman, Simon Goedegebuure, Amila Weerasinghe, Chris Wetzel, Qingsong Gao, Abimbola Oyedeji, Jacqueline Mudd, Matthew A Wyczalkowski, Michael Wendl, Li Ding, and Ryan C Fields

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Variant surface protein GP60 contributes to host infectivity of Cryptosporidium parvum, Muxiao Li, Fuxian Yang, Tianyi Hou, Xiaoqing Gong, Na Li, L David Sibley, Yaoyu Feng, Lihua Xiao, and Yaqiong Guo

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Benzodiazepine receipt in adults with psychogenic non-epileptic seizures in the USA, Kevin Young Xu, Fábio A Nascimento, Binx Yezhe Lin, Tae Woo Park, Donovan T Maust, Hillary Samples, and Greta A Bushnell

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Design of a tool capable of assessing environmental sociocultural physical factors influencing women's decisions on when and where to toilet within real-world settings: Protocol for the build and usability testing of a mobile app for use by community-dwelling women, Janis M Miller, Jean F Wyman, Lawrence An, Haitao Chu, Cynthia S Fok, Missy Lavender, Cora Elizabeth Lewis, Alayne D Markland, Leslie M Rickey, Ying Sheng, Siobhan Sutcliffe, Lisa Kane Low, and Elizabeth R Mueller

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Effect of whole bowel irrigation for ingested lead-containing foreign bodies: A pediatric case series, Frank Dicker, Michael Mullins, and David Liss

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Fueling the heart: What are the optimal dietary strategies in heart failure?, Anahita Ataran, Alexander Pompian, Hamidreza Hajirezaei, Rehman Lodhi, and Ali Javaheri

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Generalized encoding of the relative subjective value of cognitive effort in the dorsal ACC, Jennifer L Crawford, Rachel E Brough, Sarah A Eisenstein, Jonathan E Peelle, and Todd S Braver

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ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts, Konrad Hoeft, Benjamin D. Humphreys, and et al.

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Clinical-transcriptional prioritization of the circulating proteome in human heart failure, Andrew S Perry, Junedh Amrute, Kory J Lavine, and et al.

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Host-derived CEACAM-laden vesicles engage enterotoxigenic Escherichia coli for elimination and toxin neutralization, Alaullah Sheikh, Debayan Ganguli, Tim J Vickers, Marjahan Akhtar, Nazia Khatoon, Bipul Setu, Supratim Basu, Wandy L Beatty, James M Fleckenstein, and et al.

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Myotube guidance: Shaping up the musculoskeletal system, Aaron N Johnson

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Recent advancements in cell-based therapies in melanoma, George Nassief, Angela Anaeme, Karen Moussa, Abdallah N Mansour, and George Ansstas

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Use of guideline-recommended heart failure drugs in high-, middle-, and low-income countries: A systematic review and meta-analysis, Gautam Satheesh, Rupasvi Dhurjati, Laura Alston, Fisaha Tesfay, Rashmi Pant, Ehete Bahiru, Claudia Bambs, Anubha Agarwal, Sanne A E Peters, Abdul Salam, and Isabelle Johansson

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Adverse cardiovascular and kidney outcomes in people with SARS-CoV-2 treated with SGLT2 inhibitors, Taeyoung Choi, Yan Xie, and Ziyad Al-Aly

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Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of Toxoplasma gondii, Jing Xia, Yong Fu, Wanyi Huang, Taher Uddin, and L David Sibley

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Prenatal environment is associated with the pace of cortical network development over the first three years of life, Ursula A Tooley, Aidan Latham, Jeanette K Kenley, Dimitrios Alexopoulos, Tara A Smyser, Ashley N Nielsen, Lisa Gorham, Barbara B Warner, Joshua S Shimony, Jeffrey J Neil, Joan L Luby, Deanna M Barch, Cynthia E Rogers, and Christopher D Smyser

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Conditioning with anti-CD47 and anti-CD117 plus JAK inhibition enables toxic payload-free allogeneic transplantation, Stephen P Persaud, Aditya R Yelamali, Julie K Ritchey, and John F DiPersio

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Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors, Jana Willim, Weimin Yuan, Anika Lindsey, Omar Itani, Gary A Silverman, Stephen C Pak, Tim Schedl, and et al.

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Smoking and alcohol by HPV status in head and neck cancer: A Mendelian randomization study, Abhinav Thakral, Laura Bierut, and et al.

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Menopausal hormone therapy use among postmenopausal women, Lin Yang and Adetunji T Toriola

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Novel cyclic homogeneous oscillation detection method for high accuracy and specific characterization of neural dynamics, Hohyun Cho, Markus Adamek, Jon T Willie, and Peter Brunner

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Adjunctive intravenous argatroban or eptifibatide for ischemic stroke, Opeolu Adeoye, Peter Panagos, Stephanie Pizzella, and et al.

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Efficacy of PARP inhibitor therapy after targeted BRAF/MEK failure in advanced melanoma, Jordan Phillipps, George Nassief, Renee Morecroft, Tolulope Adeyelu, Andrew Elliott, Farah Abdulla, Ari Vanderwalde, Soo Park, Omar Butt, Alice Zhou, and George Ansstas

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Stat3-mediated Atg7 expression regulates anti-tumor immunity in mouse melanoma, Sarah M Zimmerman, Erin Suh, Sofia R Smith, and George P Souroullas

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A genetic screen in Drosophila uncovers a role for senseless-2 in surface glia in the peripheral nervous system to regulate CNS morphology, Haluk Lacin, Yuqing Zhu, Jose T DiPaola, Beth A Wilson, Yi Zhu, and James B Skeath

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Left coronary artery compression and stent fracture following self-expanding transcatheter pulmonary valve implantation, Jeannette Wong-Siegel, Adam Naylor, and David Balzer

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Diurnal rhythms in varicella vaccine effectiveness, Dana Danino, Yoav Kalron, Jeffrey A. Haspel, and Guy Hazan

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Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism, Yiming Zhang, Cassandra B Higgins, Stefani Tica, Joshua A Adams, Jiameng Sun, Shannon C Kelly, Xiaoyu Zong, Dennis J Dietzen, Terri Pietka, Samuel J Ballentine, Leah P Shriver, Gary J Patti, Yin Cao, and Brian J DeBosch

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Prognostic significance and biologic associations of senescence-associated secretory phenotype biomarkers in heart failure, Oday Salman, Ali Javaheri, Douglas L Mann, and et al.

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Proteomic correlates and prognostic significance of kidney injury in heart failure with preserved ejection fraction, Oday Salman, Ali Javaheri, Douglas L Mann, and et al.

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Stabilization of interdomain closure by a G protein inhibitor, Tyson D Todd, Neha Vithani, Sukrit Singh, Gregory R Bowman, Kendall J Blumer, and Andrea Soranno

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Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids, Kanve N Suvilesh, Yariswamy Manjunath, Yulia I Nussbaum, Mohamed Gadelkarim, Murugesan Raju, Akhil Srivastava, Guangfu Li, Wesley C Warren, Chi-Ren Shyu, Feng Gao, Matthew A Ciorba, Jonathan B Mitchem, Satyanarayana Rachagani, and Jussuf T Kaifi

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Use of palliative care among adults with newly diagnosed heart failure: Insights from a US national insured patient sample, Zidong Zhang, Divya S Subramaniam, Steven W Howard, Kenton J Johnston, William H Frick, Kimberly Enard, and Leslie Hinyard

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Fetal MAVS and type I IFN signaling pathways control ZIKV infection in the placenta and maternal decidua, Yael Alippe, Leran Wang, Reyan Coskun, Stéfanie P Muraro, Fang R Zhao, Michelle Elam-Noll, J Michael White, Daiana M Vota, Vanesa C Hauk, Jeffrey I Gordon, Scott A Handley, and Michael S Diamond

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A damaging COL6A3 variant alters the MIR31HG-regulated response of chondrocytes in neocartilage organoids to hyperphysiologic mechanical loading, Niek Gc Bloks, Zainab Harissa, Giorgia Mazzini, Shaunak S Adkar, Amanda R Dicks, Ghazaleh Hajmousa, Nancy Steward, Roman I Koning, Aat Mulder, Berend B R de Koning, Margreet Kloppenburg, Rodrigo Coutinho de Almeida, Yolande Fm Ramos, Farshid Guilak, and Ingrid Meulenbelt

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"Allowing space for voice…all our voices:" Understanding Ho'ouna Pono implementation through educational leadership perspectives in rural Hawai'i schools, Kelsie H Okamura, Tessa Palafu, Katlyn An, Sarah Momilani Marshall, Steven Keone Chin, Kelly A Stern, Byron J Powell, Sara J Becker, David S Mandell, and Scott K Okamoto

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American Association of Plastic Surgeons consensus on breast implant-associated anaplastic large-cell lymphoma, Mark W. Clemens, Terence M. Myckatyn, Arianna Di Napoli, Andrew L. Feldman, Elaine S. Jaffe, Cara L. Haymaker, Steven M. Horwitz, Kelly K. Hunt, Marshall E. Kadin, Colleen M McCarthy, Roberto N. Miranda, H. Miles Prince, Fabio Santanelli di Pompeo, Sari D. Holmes, and Linda G. Phillips

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An expert discussion on the atypical hemolytic uremic syndrome nomenclature-identifying a road map to precision: A report of a National Kidney Foundation Working Group, Carla M Nester, Anuja Java, and et al.

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An interpretable machine learning-based cerebrospinal fluid proteomics clock for predicting age reveals novel insights into brain aging, Justin Melendez, Yun Ju Sung, Miranda Orr, Andrew Yoo, Suzanne Schindler, Carlos Cruchaga, and Randall Bateman

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An ordinal clinical score predicts seizure freedom after minimally invasive epilepsy surgery, Adam S Dickey, Katie L Bullinger, Dayton Grogan, Melissa M Asmar, Abdulrahman Alwaki, Ammar Kheder, Veeresh Kumar N Shivamurthy, Razan R Faraj, Alexander Greven, Jon T Willie, Daniel L Drane, and Robert E Gross

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A novel antigen biomarker for detection of high-level of Loa loa microfilaremia, Sarah E Greene, Yuefang Huang, Kerstin Fischer, Bruce A. Rosa, John Martin, Makedonka Mitreva, Devyn Yates, Samuel Wanji, Joseph Kamgno, Philip J. Budge, Gary J. Weil, and Peter U. Fischer

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Antiretroviral therapy and cardiovascular risk in people with HIV in the United States-an updated analysis, Luis Parra-Rodriguez, John M Sahrmann, Anne M Butler, Margaret A Olsen, William G Powderly, and Jane A O'Halloran

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A podcast on practical considerations in patients with advanced urothelial cancer receiving first-line cisplatin- or carboplatin-based chemotherapy followed by avelumab maintenance in a changing therapeutic landscape, Jun Gong and Melissa A Reimers

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A systematic review to compare electrical, magnetic, and optogenetic stimulation for peripheral nerve repair, Priya Kaluskar, Dhruv Bharadwaj, K Swaminathan Iyer, Christopher Dy, Minghao Zheng, and David M Brogan

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Beta-hydroxybutyrate levels and risk of diabetic ketoacidosis in adults with type 1 diabetes treated with sotagliflozin, Schafer Boeder, Michael J Davies, Janet B McGill, Richard Pratley, Manon Girard, Phillip Banks, Jeremy Pettus, and Satish Garg

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Clinical practice recommendations for hematopoietic cell transplantation and cellular therapies in follicular lymphoma: A collaborative effort on behalf of the American Society for Transplantation and Cellular Therapy and the European Society for Blood and Marrow Transplantation, Madiha Iqbal, Brad S Kahl, and et al.

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Comparison of outcomes of abdominoperineal resection vs low anterior resection in very-low rectal cancer, Roberta L Muldoon, Alva J Bethurum, Adriana C Gamboa, Kevin Zhang, Fei Ye, Scott E Regenbogen, Sherif Abdel-Misih, Aslam Ejaz, Paul E Wise, Matthew Silviera, Jennifer Holder-Murray, Glen C Balch, and Alexander T Hawkins

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Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes, Sheri Skerget, Ravi Vij, and et al.

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Concepts of pain management following nerve injuries: Multidisciplinary approach, Amanda Faust, Stephen J DeMartini, Abigail Carey-Ewend, Lara W Crock, Sarah K Buday, David M Brogan, and Christopher J Dy

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Cyclic testing of six-strand suture techniques for zone 2 flexor tendon lacerations, Nozomu Kusano, Melissa A Zaegel, and Matthew J Silva

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Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc, James Melrose and Farshid Guilak

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Dynamic changes in circulating tumor fraction as a predictor of real-world clinical outcomes in solid tumor malignancy patients treated with immunotherapy, Ryan D Gentzler, Aadel A Chaudhuri, and et al.

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Endogenous base damage as a driver of genomic instability in homologous recombination-deficient cancers, Lindsey N Aubuchon and Priyanka Verma

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Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration, Sung Ho Moon, Xinping Liu, Christopher M Jenkins, Beverly Gibson Dilthey, Gary J Patti, and Richard W Gross