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Submissions from 2023

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Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency, Yanfeng Li, Chandan Guha, Patrik Asp, Xia Wang, Tatyana L. Tchaikovskya, Kenneth Kim, Matthew Mendel, Gregory J. Cost, David H. Perlmutter, Namita Roy-Chowdhury, Ira J. Fox, Anthony Conway, and Jayanta Roy-Chowdhury

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Selective dorsal rhizotomy for treatment of spasticity after hemispherectomy in children: A case report, TS Park, Susan Joh, Matthew D. Smyth, Nicole L. Meyer, and Deanna M. Walter

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Society for Immunotherapy of Cancer (SITC) consensus definitions for resistance to combinations of immune checkpoint inhibitors with chemotherapy, Naiyer Rizvi, Foluso O. Ademuyiwa, Z Alexander Cao, Helen X. Chen, Robert L. Ferris, Sarah B. Goldberg, Matthew D. Hellmann, Ranee Mehra, Ina Rhee, Jong Chul Park, Harriet Kluger, Hussein Tawbi, and Ryan J. Sullivan

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Strengthening implementation guidelines for HIV service delivery: Considerations for future evidence generation and synthesis, Ingrid Eshun-Wilson, Nathan Ford, Aaloke Mody, Laura Beres, Sheree Schwartz, Stefan Baral, and Elvin H. Geng

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Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer, Valerie W Rusch, G Alexander Patterson, Salama N Waqar, and et al.

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Targeted deletion of Fgf9 in tendon disrupts mineralization of the developing enthesis, Elahe Ganji, Connor Leek, William Duncan, Debabrata Patra, David M Ornitz, and Megan L Killian

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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia, Ghayas C Issa, John DiPersio, Shalini Shenoy, and et al.

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TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability, Surbhi Chouhan, Mithila Sawant, Cody Weimholt, Jingqin Luo, Robert W Sprung, Mailyn Terrado, David M Mueller, H Shelton Earp, and Nupam P. Mahajan

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Venographic classification and long-term surgical treatment outcomes for axillary-subclavian vein thrombosis due to venous thoracic outlet syndrome (Paget-Schroetter syndrome), Esmaeel Reza Dadashzadeh, J. Westley Ohman, Pavan K. Kavali, Karen M. Henderson, Danita M. Goestenkors, and Robert W. Thompson

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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia, Mohamed Eldeeb, Ouyang Yuan, Nicola Guzzi, Phuong Cao Thi Ngoc, Anna Konturek-Ciesla, Trine A Kristiansen, Sowndarya Muthukumar, Jeffrey Magee, Cristian Bellodi, Joan Yuan, and David Bryder

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Apical secretory glycoprotein complex contributes to cell attachment and entry by Cryptosporidium parvum, Marianna E. Akey, Rui Xu, Soumya Ravindran, Lisa Funkhouser-Jones, and L. David Sibley

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Engineering a modular 44Ti/44Sc generator: Eluate evaluation in preclinical models and estimation of human radiation dosimetry, Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E Rodgers, Diane Abou, Valery Radchenko, and Daniel L J Thorek

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Mucosal and systemic neutralizing antibodies to norovirus induced in infant mice orally inoculated with recombinant rotaviruses, Takahiro Kawagishi, Liliana Sánchez-Tacuba, Ningguo Feng, Veronica P Costantini, Ming Tan, Xi Jiang, Kim Y Green, Jan Vinjé, Siyuan Ding, and Harry B Greenberg

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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes, Anastasiia Gainullina, Denis A Mogilenko, Li-Hao Huang, Ki-Wook Kim, Karen Krchma, Jun Wu, Geetika Bajpai, Peter Wang, Kyunghee Choi, Kory Lavine, Gwendalyn J Randolph, Alexey Sergushichev, Maxim N Artyomov, and et al.

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Single cell preparations of Mycobacterium tuberculosis damage the mycobacterial envelope and disrupt macrophage interactions, Ekansh Mittal, Andrew T Roth, Anushree Seth, Srikanth Singamaneni, Wandy Beatty, and Jennifer A Philips

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The ER protein translocation channel subunit Sbh1 controls virulence of Cryptococcus neoformans, Felipe H. Santiago-Tirado, Thomas Hurtaux, Jennifer Geddes-McAlister, Duy Nguyen, Volkhard Helms, Tamara L Doering, and Karin Römisch

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Virology under the microscope-A call for rational discourse, Felicia Goodrum, Carolina Lopez, Sean Whelan, and et al.

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Zika virus spreads through infection of lymph node-resident macrophages, Glennys V Reynoso, Autumn C Holmes, Yael Alippe, Michael S Diamond, and et al.

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Care of bullet-related injuries: A cross-sectional study of instructions and prescriptions provided on discharge from the emergency department, Jane M. Hayes, L J. Punch, and Kristen L. Mueller

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Orthodenticle homeobox 2 is transported to lysosomes by nuclear budding vesicles, Jun Woo Park, Eun Jung Lee, Eunyoung Moon, Hong-Lim Kim, In-Beom Kim, Didier Hodzic, Namsuk Kim, Hee-Seok Kweon, and Jin Woo Kim

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Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1, Philipp A M Schmidpeter, John T Petroff 2nd, Leila Khajoueinejad, Aboubacar Wague, Cheryl Frankfater, Wayland W L Cheng, Crina M Nimigean, and Paul M Riegelhaupt

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Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis, Jordan M Johnson, Irfan J Lodhi, and Et al.

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[18F]Tosyl fluoride as a versatile [18F]fluoride source for the preparation of 18F-labeled radiopharmaceuticals, Dong Zhou, Wenhua Chu, Jinbin Xu, Sally Schwarz, and John A Katzenellenbogen

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Allogeneic natural killer cell therapy, Melissa M Berrien-Elliott, Miriam T Jacobs, and Todd A Fehniger

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Child Adult Relationship Enhancement in Primary Care (PriCARE): Study design/protocol for a randomized trial of a primary care-based group parenting intervention to prevent child maltreatment, Samantha Schilling, Byron J Powell, Paul W Stewart, and Joanne N Wood

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Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma, Nicole Thomas, Nancy L. Bartlett, Lee Ratner, and et al.

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Using wearable sensors to assess freezing of gait in the real world, David S May, Lauren E Tueth, Gammon M Earhart, and Pietro Mazzoni

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Identifying factors which influence eating disorder risk during behavioral weight management: A consensus study, Hiba Jebeile, Caitlin M McMaster, Brittany J Johnson, Sarah P Garnett, Susan J Paxton, Anna L Seidler, Rebecca A Jones, Andrew J Hill, Sarah Maguire, Caroline Braet, Genevieve Dammery, Denise E Wilfley, Louise A Baur, Natalie B Lister, and on behalf of the Eating Disorders In weight-related Therapy (EDIT) Collaboration

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SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis, Yuchen Xie, Merve Sahin, Toru Wakamatsu, Akane Inoue-Yamauchi, Wanming Zhao, Song Han, Amrita M. Nargund, Shaoyuan Yang, Yang Lyu, James J. Hsieh, Christina S. Leslie, and Emily H. Cheng

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Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes, Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, and Farshid Guilak

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The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments, Wenyan Wan, Hui Dong, De-Hua Lai, Jiong Yang, Kai He, Xiaoyan Tang, Qun Liu, Geoff Hide, Xing-Quan Zhu, L David Sibley, Zhao-Rong Lun, and Shaojun Long

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Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods, Miikael Lehtimäki, Binisha H Mishra, Coral Del-Val, Leo-Pekka Lyytikäinen, Mika Kähönen, C Robert Cloninger, Olli T Raitakari, Reijo Laaksonen, Igor Zwir, Terho Lehtimäki, and Pashupati P Mishra

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CCL17 protects against viral myocarditis by suppressing the recruitment of regulatory T cells, Guoshuai Feng, Cuige Zhu, Chieh-Yu Lin, Andrea Bredemeyer, Irmgard Förster, Daniel Kreisel, and Kory J Lavine

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Creating research-ready partnerships: The initial development of seven implementation laboratories to advance cancer control, Gina R Kruse, Erica Hale, Justin E Bekelman, Jennifer E DeVoe, Rachel Gold, Peggy A Hannon, Thomas K Houston, Aimee S James, Ashley Johnson, Lisa M Klesges, and Andrea L Nederveld

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Effects of particle diameter and inlet flow rate on gas-solid flow patterns of fluidized bed, Zhenjiang Zhao, Ling Zhou, Ling Bai, Wanning Lv, and Ramesh K Agarwal

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Efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute pain after orthopedic trauma: A practice management guideline from the Eastern Association for the Surgery of Trauma and the Orthopedic Trauma Association, Patrick B. Murphy, Anna Miller, and et al.

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Predicting later categories of upper limb activity from earlier clinical assessments following stroke: An exploratory analysis, Jessica Barth, Keith R Lohse, Marghuretta D Bland, and Catherine E Lang

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The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers, Rebeca Scalco, Richard J Perrin, and et al.

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Hydrogel encapsulation of genome-engineered stem cells for long-term self-regulating anti-cytokine therapy, Kelsey H Collins, Lara Pferdehirt, Leila S Saleh, Alireza Savadipour, Luke E Springer, Kristin L Lenz, Dominic M Thompson, Sara J Oswald, Christine T N Pham, and Farshid Guilak

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TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma, Maximilian O. Schaettler, Rupen Desai, Anthony Z. Wang, Alexandra J. Livingstone, Dale K. Kobayashi, Andrew T. Coxon, Jay A. Bowman-Kirigin, Connor J. Liu, Mao Li, Diane E. Bender, Michael J. White, David M. Kranz, Tanner M. Johanns, and Gavin P. Dunn

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The gut microbiota of people with asthma influences lung inflammation in gnotobiotic mice, Naomi G Wilson, Ariel Hernandez-Leyva, Anne L Rosen, Natalia Jaeger, Ryan T McDonough, Jesus Santiago-Borges, Michael A Lint, Thomas R Rosen, Christopher P Tomera, Leonard B Bacharier, S Joshua Swamidass, and Andrew L Kau

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Hallmarks of neurodegenerative diseases, David M Wilson 3rd, Mark R Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David M Holtzman, and Ilse Dewachter

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Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias, Robert J Jirsaraie, Tobias Kaufmann, Vishnu Bashyam, Guray Erus, Joan L Luby, Lars T Westlye, Christos Davatzikos, Deanna M Barch, and Aristeidis Sotiras

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Developmental programming: Adverse sexually dimorphic transcriptional programming of gestational testosterone excess in cardiac left ventricle of fetal sheep, Venkateswaran Ramamoorthi Elangovan, Nadia Saadat, Adel Ghnenis, Vasantha Padmanabhan, and Arpita K Vyas

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FMR1 mutation alters the early development of sensory coding and hunting and social behaviors in larval zebrafish, Shuyu I Zhu, Michael H McCullough, Zac Pujic, Jordan Sibberas, Biao Sun, Thomas Darveniza, Bianca Bucknall, Lilach Avitan, and Geoffrey J Goodhill

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Spontaneous coronary artery dissection complicated by left ventricular free wall rupture in Turner syndrome, Brendan F Caprio, Kunal Kotkar, Alan Zajarias, and Alan C Braverman

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SVEP1 is an endogenous ligand for the orphan receptor PEAR1, Jared S Elenbaas, Upasana Pudupakkam, Katrina J Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C Lee, Kendall H Burks, Junedh M Amrute, Robert P Mecham, Carmen M Halabi, Arturo Aliso, Jorge Di Paola, and Nathan O Stitziel

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Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms, Melissa D Stuchell-Brereton, Maxwell I Zimmerman, Justin J Miller, Upasana L Mallimadugula, J Jeremías Incicco, Debjit Roy, Louis G Smith, Jasmine Cubuk, Berevan Baban, Gregory T DeKoster, Carl Frieden, Gregory R Bowman, and Andrea Soranno

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Brain aerobic glycolysis and resilience in Alzheimer disease, Manu S Goyal, Tyler Blazey, Nicholas V Metcalf, Mark P McAvoy, Jeremy F Strain, Maryam Rahmani, Tony J Durbin, Chengjie Xiong, Tammie L-S Benzinger, John C Morris, Marcus E Raichle, and Andrei G Vlassenko

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mRNA vaccine mitigates SARS-CoV-2 infections and COVID-19, Christina M. Kackos, Sherri L. Surman, Bart G. Jones, Robert E. Sealy, Trushar Jeevan, Christopher J H Davitt, Sergei Pustylnikov, Tamarand L. Darling, Adrianus C M Boon, Julia L. Hurwitz, Marcelo M. Samsa, and Richard J. Webby

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Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration, Rui Feng, Vishnu Muraleedharan Saraswathy, Mayssa H Mokalled, and Valeria Cavalli

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Staphylococcus aureus breast implant infection isolates display recalcitrance to antibiotic pocket irrigants, Jesus M. Duran Ramirez, Jana Gomez, Blake M. Hanson, Taha Isa, Terence M. Myckatyn, and Jennifer N. Walker

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Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity, Yu H Sun, Xiaoyu Zhuo, and et al.

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Community research fellows training program: Evaluation of a COVID-19-precipitated virtual adaptation, Nicole Ackermann, Sarah Humble, Jacquelyn V Coats, Carlette Lewis Rhone, Craig Schmid, Vetta Sanders Thompson, and Kia L Davis

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Rate of tarsal and metatarsal bone mineral density change in adults with diabetes mellitus and peripheral neuropathy: A longitudinal study, Nicholas J Youmans, Rachana S Vaidya, Ling Chen, Hyo-Jung Jeong, Alexa York, Paul K Commean, Mary K Hastings, and Jennifer A Zellers

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Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: A subset analysis of the phase 3, randomized, controlled ASPECT-NP trial, Ignacio Martin-Loeches, Andrew F Shorr, Richard G Wunderink, Marin H Kollef, Jean-François Timsit, Brian Yu, Jennifer A Huntington, Erin Jensen, and Christopher J Bruno

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Phase Ib study of telisotuzumab vedotin in combination with erlotinib in patients with c-Met protein-expressing non-small-cell lung cancer, D Ross Camidge, Daniel Morgensztern, and et al.

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Chikungunya virus and its envelope protein E2 induce hyperalgesia in mice: Inhibition by anti-E2 monoclonal antibodies and by targeting TRPV1, Carina Z Segato-Vendrameto, Felipe A Pinho-Ribeiro, and et al.

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Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis, María Piedad Menéndez-Gutiérrez, Jesús Porcuna, Ramesh Nayak, Ana Paredes, Haixia Niu, Vanessa Núñez, Aditi Paranjpe, Manuel J Gómez, Anukana Bhattacharjee, Daniel J Schnell, Fátima Sánchez-Cabo, John S Welch, Nathan Salomonis, Jose A Cancelas, and Mercedes Ricote

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The mechanism of enantioselective neurosteroid actions on GABA, Hiroki Tateiwa, Satyanarayana M Chintala, Ziwei Chen, Lei Wang, Fatima Amtashar, John Bracamontes, Allison L Germann, Spencer R Pierce, Douglas F Covey, Gustav Akk, and Alex S Evers

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Body mass index and molecular subtypes of colorectal cancer, Neil Murphy, Yin Cao, and et al.

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Incidence, attributable mortality, and healthcare and out-of-pocket costs of Clostridioides difficile infection in US Medicare Advantage Enrollees, Holly Yu, Tamuno Alfred, Jennifer L Nguyen, Jingying Zhou, and Margaret A Olsen

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Protection of messenger RNA vaccines against hospitalized coronavirus disease 2019 in adults over the first year following authorization in the United States, Mark W Tenforde, Hilary M Babcock, Jennie H Kwon, and et al.

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The impact of universal glove and gown use on Clostridioides difficile acquisition: A cluster-randomized trial, Daniel J Morgan, Erik R Dubberke, Tiffany Hink, Gwen Paszkiewicz, Carey-Ann D Burnham, Lisa Pineles, Larry Magder, J Kristie Johnson, Surbhi Leekha, and Anthony D Harris

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Evaluation of apparent diffusion coefficient repeatability and reproducibility for preclinical MRIs using standardized procedures and a diffusion-weighted imaging phantom, Dariya Malyarenko, Ghoncheh Amouzandeh, Stephen Pickup, Rong Zhou, Henry Charles Manning, Seth T Gammon, Kooresh I Shoghi, James D Quirk, Renuka Sriram, Peder Larson, Michael T Lewis, Robia G Pautler, Paul E Kinahan, Mark Muzi, and Thomas L Chenevert

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Fifty years of global cardiovascular research in Africa: A scientometric analysis, 1971 to 2021, Jean Jacques Noubiap, Dominic Millenaar, Dike Ojji, Q Eileen Wafford, Christian Ukena, Michael Böhm, Karen Sliwa, Mark D Huffman, and Felix Mahfoud

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Prognostic significance of early platelet dynamics in Staphylococcus aureus bacteremia, Rachid Douglas-Louis, Mimi Lou, Brian Lee, Emi Minejima, Juliane Bubeck-Wardenburg, and Annie Wong-Beringer

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Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy, Shuman Peng, Yuting Zhan, Dongqi Zhang, Lu Ren, Anqi Chen, Zhou-Feng Chen, and Haitao Zhang

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Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers, James J Harding, Haeseong Park, and et al.

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Improving communication in intensive care unit to ward transitions: Protocol for multisite national implementation of the ICU-PAUSE handoff tool, Elle Mizuki Fukui, Patrick G Lyons, Emily Harris, Emma K McCune, Juan C Rojas, and Lekshmi Santhosh

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Ion channel regulation of gut immunity, Jing Feng, Zili Xie, and Hongzhen Hu

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The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition, Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S Clemen, Conrad C Weihl, John G Purdy, Steve P Gygi, and Malavika Raman

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Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes, Mayank N K Choudhary, Kara Quaid, Xiaoyun Xing, Heather Schmidt, and Ting Wang

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Preclinical efficacy of a PARP-1 targeted Auger-emitting radionuclide in prostate cancer, Sreeja Sreekumar, Dong Zhou, Cedric Mpoy, Elsa Schenk, Jalen Scott, Jeffrey M Arbeit, Jinbin Xu, and Buck E Rogers

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Microbes, histology, blood analysis, enterotoxins, and cytokines: Findings from the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 3, Patricia McGuire, Caroline Glicksman, Roger Wixtrom, C James Sung, Robert Hamilton, Marisa Lawrence, Melinda Haws, Sarah Ferenz, and Marshall Kadin

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NetProphet 3: A machine learning framework for transcription factor network mapping and multi-omics integration, Dhoha Abid and Michael R Brent

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SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids, Yukitoshi Izumi, Angela M Reiersen, Eric J Lenze, Steven J Mennerick, and Charles F Zorumski

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The efficacy of a posterior approach to surgical correction for neglected idiopathic scoliosis: A comparative analysis according to health-related quality of life, pulmonary function, back pain and sexual function, Pawel Grabala, Ilkka J Helenius, Jacob M Buchowski, and Suken A Shah

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Presence of trans-fatty acids containing ingredients in pre-packaged foods and the availability of reported trans-fat levels in Kenya and Nigeria, Liping Huang, Adedayo E Ojo, Judith Kimiywe, Alex Kibet, Boni M Ale, Clementina E Okoro, Jimmy Louie, Fraser Taylor, Mark D Huffman, Dike B Ojji, Jason H Y Wu, and Matti Marklund

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Autophagy requirements for eye lens differentiation and transparency, Lisa Brennan, M Joseph Costello, J Fielding Hejtmancik, A Sue Menko, S Amer Riazuddin, Alan Shiels, and Marc Kantorow

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BrainWAVE: A flexible method for noninvasive stimulation of brain rhythms across species, Matthew K. Attokaren, Nuri Jeong, Lou Blanpain, Abigail L. Paulson, Kristie M. Garza, Ben Borron, Michael Walelign, Jon Willie, and Annabelle C. Singer

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Clinical importance of clonal hematopoiesis in metastatic gastrointestinal tract cancers, Bill H Diplas, Kelly Bolton, and et al.

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Dexamethasone to prevent everolimus-induced stomatitis (Alliance MIST trial: A221701), Kathryn J Ruddy, David Zahrieh, Jun He, Blake Waechter, Julianne L Holleran, Lionel D Lewis, Selina Chow, Jan Beumer, Matthias Weiss, Nikolaos Trikalinos, Bryan Faller, Maryam Lustberg, Hope S Rugo, and Charles Loprinzi

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Dissecting cell identity via network inference and in silico gene perturbation, Kenji Kamimoto, Blerta Stringa, Christy M Hoffmann, Kunal Jindal, Lilianna Solnica-Krezel, and Samantha A Morris

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Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases, Yehuda Handelsman, Samuel Klein, and et al.

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Extending outbreak investigation with machine learning and graph theory: Benefits of new tools with application to a nosocomial outbreak of a multidrug-resistant organism, Andrew Atkinson, Benjamin Ellenberger, Vanja Piezzi, Tanja Kaspar, Luisa Salazar-Vizcaya, Olga Endrich, Alexander B Leichtle, and Jonas Marschall

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Final findings from the CONTROL trial: Strategies to reduce the incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer, Arlene Chan, Ron Bose, and et al.

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Final results from a phase 2b randomized, placebo-controlled clinical trial of RBX2660: A microbiota-based drug for the prevention of recurrent Clostridioides difficile infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, and Christine Lee

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Fixed-dose combination therapy-based protocol compared with free pill combination protocol: Results of a cluster randomized trial, Olutobi A Sanuade, Mark D Huffman, and et al.

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Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition, Elizabeth E Palmer, Linda J Richards, and et al.

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Genetic and environmental variation in continuous phenotypes in the ABCD Study®, Hermine H M Maes, Dana M Lapato, J Eric Schmitt, Monica Luciana, Marie T Banich, James M Bjork, John K Hewitt, Pamela A Madden, Andrew C Heath, Deanna M Barch, Wes K Thompson, William G Iacono, and Michael C Neale

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Human cardiac pericytes are susceptible to SARS-CoV-2 infection, Brittany D Brumback, Oleksandr Dmytrenko, Ashley N Robinson, Adam L Bailey, Pan Ma, Jing Liu, Stephanie C Hicks, Sherwin Ng, Gang Li, David M Zhang, Catherine E Lipovsky, Chieh-Yu Lin, Michael S Diamond, Kory J Lavine, and Stacey L Rentschler

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Identification of bradycardia following remdesivir administration through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic Pharmacovigilance Project, Jason M Devgun, Rongmei Zhang, Jeffrey Brent, Paul Wax, Keith Burkhart, Alison Meyn, Sharan Campleman, Stephanie Abston, Kim Aldy, and Toxicology Investigators Consortium FACT Study Group

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In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector, Reka Lorincz, Aluet Borrego Alvarez, Christopher J Walkey, Samir A Mendonça, Zhi Hong Lu, Alexa E Martinez, Cecilia Ljungberg, Jason D Heaney, William R Lagor, and David T Curiel

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Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity, Jennifer M Brazill, David Shin, Kristann Magee, Anurag Majumdar, Ivana R Shen, Valeria Cavalli, and Erica L Scheller

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LATE-NC staging in routine neuropathologic diagnosis: An update, Peter T Nelson, Katherine E Schwetye, and et al.

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LGMDD1 natural history and phenotypic spectrum: Implications for clinical trials, Andrew R Findlay, Sarah E Robinson, Stephanie Poelker, Michelle Seiffert, Rocio Bengoechea, and Conrad C Weihl

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Machine learning approximations to predict epigenetic age acceleration in stroke patients, Isabel Fernández-Pérez, Joan Jiménez-Balado, Uxue Lazcano, Eva Giralt-Steinhauer, Lucía Rey Álvarez, Elisa Cuadrado-Godia, Ana Rodríguez-Campello, Adrià Macias-Gómez, Antoni Suárez-Pérez, Anna Revert-Barberá, Isabel Estragués-Gázquez, Carolina Soriano-Tarraga, Jaume Roquer, Angel Ois, and Jordi Jiménez-Conde

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Missed opportunities in the diagnosis of tuberculosis meningitis, Niamh Simmons, Margaret A Olsen, Joanna Buss, Thomas C Bailey, and Carlos Mejia-Chew

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Modulation of TRPV4 protects against degeneration induced by sustained loading and promotes matrix synthesis in the intervertebral disc, Garrett W D Easson, Alireza Savadipour, Akila Anandarajah, Leanne E Iannucci, Spencer P Lake, Farshid Guilak, and Simon Y Tang