The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2014

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RON5 is critical for organization and function of the Toxoplasma moving junction complex, Josh R. Beck, Allan L. Chen, Elliot W. Kim, and Peter J. Bradley

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Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development, Michael S. Behnke, Tiange P. Zhang, Jitender P. Dubey, and L. David Sibley

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Differential induction of TLR3-dependent innate immune signaling by closely related parasite species, Daniel P. Beiting, Lucia Peixoto, Natalia S. Akopyants, Stephen M. Beverley, E. John Wherry, David A. Christian, Christopher A. Hunter, Igor E. Brodsky, and David S. Roos

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Neural activation associated with the cognitive emotion regulation of sadness in healthy children, Andy C. Belden, Joan L. Luby, David Pagliaccio, and Deanna M. Barch

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Retinopathy and clinical outcomes in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia, Natalie A. Bello, Marc A. Pfeffer, Hicham Skali, Janet B. McGill, Jerome Rossert, Kurt A. Olson, Larry Weinrauch, Mark E. Cooper, Dick de Zeeuw, Peter Rossing, John J. V. McMurray, Scott D. Solomon, and Trial to Reduce cardiovascular Events with Aranesp Therapy (TREAT) Investigators

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Chronic lung allograft dysfunction following lung transplantation: Challenges and solutions, Bradford C. Bemiss and Chad A. Witt

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Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury, Rachel E. Bennett and David L. Brody

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Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma, Thomas M. Bennett, Donna S. Mackay, Carla J. Siegfried, and Alan Shiels

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Driving self-restriction and age: A study of emergency department patients, Marian E. Betz, Christopher R. Carpenter, Emma Genco, and David B. Carr

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Astrocytes modulate the polarization of CD4+ T cells to Th1 cells, Eleonore Beurel, Laurie E. Harrington, William Buchser, Vance Lemmon, and Richard S. Jope

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Developmental differences in masked form priming are not driven by vocabulary growth, Adeetee Bhide, Bradley L. Schlaggar, and Kelly Anne Barnes

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Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing, Seweryn Bialasiewicz, Jodie McVernon, Terry Nolan, Stephen B. Lambert, Guoyan Zhao, David Wang, Michael D. Nissen, and Theo P. Sloots

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Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6, Martina Bielaszewska, Roswitha Schiller, Lydia Lammers, Andreas Bauwens, Angelika Fruth, Barbara Middendorf, M. Alexander Schmidt, Phillip I. Tarr, Ulrich Dobrindt, Helge Karch, and Alexander Mellmann

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Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors, Gabriel A. Bien-Willner and Robi D. Mitra

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Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation, Sofie Bjorner, Paul A. Fitzpatrick, Yaoyong Li, Craig Allred, Anthony Howell, Anita Ringberg, Hakan Olsson, Crispin J. Miller, Hakan Axelson, and Goran Landberg

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Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia, Kevin J. Black, Abraham Z. Snyder, Jonathan W. Mink, Veeral N. Tolia, Fredy J. Revilla, Stephen M. Moerlein, and Joel S. Perlmutter

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Case records of the Massachusetts General Hospital. Case 1-2014. A 32-year-old man with loss of vision and a rash, Melvin S. Blanchard, Javier M. Romero, and Mai P. Hoang

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Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver, Valerie Blanc, Eddie Park, Sabine Schaefer, Melanie MIller, Yiing Lin, Susan Kennedy, Anja M. Billing, Hisham Ben Hamidane, Johannes Graumann, Ali Mortazavi, Joseph H. Nadeau, and Nicholas O. Davidson

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Exertional sickling: Questions and controversy, Morey A. Blinder and Sarah Russel

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How to avoid microaspiration? A key element for the prevention of ventilator-associated pneumonia in intubated ICU patients, Stijn I. Blot, Jan Poelaert, and Marin Kollef

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Outcome of all-inside second-generation meniscal repair: Minimum five-year follow-up, Ljiljana Bogunovic, Lisa M. Kruse, Amanda K. Haas, Laura J. Huston, and Rick W. Wright

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The changing immune system in sepsis: Is individualized immuno-modulatory therapy the answer?, Jonathan S. Boomer, Jonathan M. Green, and Richard S. Hotchkiss

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A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice, Adrianus C.M. Boon, Robert W. Williams, David S. Sinasac, and Richard J. Webby

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Balloon occlusion retrograde transvenous obliteration of gastric varices in two non-cirrhotic patients with portal vein thrombosis, Peyman Borghei, Seung Kwon Kim, and Darryl A. Zuckerman

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Genetic suppression of transgenic APP rescues hypersynchronous network activity in a mouse model of alzeimer's disease, Heather A. Born, Ji-Yoen Kim, Ricky R. Savjani, Pritam Das, Yuri A. Dabaghian, Qinxi Guo, Jong W. Yoo, Dorothy R. Schuler, John R. Cirrito, Hui Zheng, Todd E. Golde, Jeffrey L. Noebels, and Joanna L. Jankowsky

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Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo, Marie K. Bosch, Jeanne M. Nerbonne, and David M. Ornitz

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Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus, Sandip K. Bose, Hangeun Kim, Keith Meyer, Nathan Wolins, Nicholas O. Davidson, and Ranjit Ray

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Treatment of stage I lung cancer in high-risk and inoperable patients: SBRT vs. RFA vs. sublobar resection, Matthew J. Bott and Traves Crabtree

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A new measure of fear of falling: psychometric properties of the fear of falling questionnaire revised (FFQ-R), Emily S. Bower, Julie L. Wetherell, C. C. Merz, Andrew J. Petkus, Vanessa L. Malcarne, and Eric J. Lenze

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SkpA restrains synaptic terminal growth during development and promotes axonal degeneration following injury, E. J. Brace, Chunlai Wu, Vera Valakh, and Aaron DiAntonio

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ACR appropriateness criteria® pre-irradiation evaluation and management of brain metastases, Jeffrey D. Bradley and et al

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Network-mediated encoding of circadian time: The suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back, Marco Brancaccio, Ryosuke Enoki, Cristina N. Mazuski, Jeff Jones, Jennifer A. Evans, and Abdelhalim Azzi

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Atenolol versus losartan in children and young adults with Marfan's syndrome, A C. Braverman, A M. Sharkey, and et al

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The Ca2+-activated K+ current of human sperm is mediated by Slo3, Christoph Brenker, Yu Zhou, Astrid Muller, Fabio Andres Echeverry, Christian Trotschel, Ansgar Poetsch, Xiao-Ming Xia, Wolfgang Bonigk, Christopher J. Lingle, U. Benjamin Kaupp, and Timo Strunker

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander R. Vaccaro, and Jeffrey C. Wang

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Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis, Matthew R. Brier, Jewell B. Thomas, and Beau M. Ances

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PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells, Michael D. Brooks, Erin Jackson, Nicole M. Warrington, Jingqin Luo, Jason T. Forys, Sara Taylor, Diane D. Mao, Jeffrey R. Leonard, Albert H. Kim, David Piwnica-Worms, Robi D. Mitra, and Joshua B. Rubin

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Total knee arthroplasty after previous knee surgery, Robert H. Brophy, Benjamin L. Gray, Ryan M. Nunley, Robert L. Barrack, and John C. Clohisy

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Symptoms of pain do not correlate with rotator cuff tear severity, Robert H. Brophy, Matthew V. Smith, Rick W. Wright, and et al

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Rapid ertapenem susceptibility testing and Klebsiella pneumoniae carbapenemase phenotype detection in Klebsiella pneumoniae isolates by use of automated microscopy of immobilized live bacterial cells, Carey-Ann D. Burnham, Rachel A. Frobel, Monica L. Herrera, Brian L. Wickes, and D. J. Diekema

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De novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma, Jason P. Burnham, Benjamin S. Thomas, Sergio E. Trevino, Erin McElvania TeKippe, Carey-Ann D. Burnham, and F. Matthew Kuhlmann

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Resting state functional connectivity in early blind humans, Harold Burton, Abraham Z. Snyder, and Marcus E. Raichle

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A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, and CRONICAS Cohort Study Group

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Cardiometabolic outcomes in children and adolescents following discontinuation of long-term risperidone treatment, Chadi A. Calarge, Ginger Nicol, Janet A. Schlechte, and Trudy L. Burns

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Dorsal and ventral attention systems underlie social and symbolic cueing, Alicia Callejas, Gordon L. Shulman, and Maurizio Corbetta

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miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain, Dominique Cannella, Marie-Pierre Brenier-Pinchart, Laurence Braun, Jason M. van Rooyen, Alexandre Bougdour, Olivier Bastien, Michael S. Behnke, Rose-Laurence Curt, Aurelie Curt, Jeroen P.J. Saeij, L. David Sibley, Herve Pelloux, and Mohamed-Ali Hakimi

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Pervasive transcription of a herpesvirus genome generates functionally important RNAs, Susan P. Canny, Tiffany A. Reese, L. Steven Johnson, Xin Zhang, Amal Kambal, Erning Duan, Catherine Y. Liu, and Herbert W. Virgin

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Predicting structure and stability for RNA complexes with intermolecular loop–loop base-pairing, Song Cao, Xiaojun Xu, and Shijie Chen

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Resting-state modulation of alpha rhythms by interference with angular gyrus activity, Paolo Capotosto, Claudio Babiloni, Gian Luca Romani, and Maurizio Corbetta

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Sex dependent risk factors for mortality after myocardial infarction: Individual patient data meta-analysis, Robert M. Carney, Kenneth E. Freedland, and et al

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Structure of cellular ESCRT-III spirals and their relationship to HIV budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, and Phyllis I. Hanson

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Cognitive functioning in young children with type 1 diabetes, M. A. Cato, Nelly Mauras, Jodie Ambrosino, Aiden Bondurant, Amy L. Conrad, Craig Kollman, Peiyao Cheng, Roy W. Beck, Katrina J. Ruedy, Tandy Aye, Allan L. Reiss, Neil H. White, and Tamara Hershey

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B-RAF unlocks axon regeneration, Valeria Cavalli and David Holtzman

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Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders, P. A. Cavazos-Rehg, N. Breslau, D. Hatsukami, M. J. Krauss, E. L. Spitznagel, R. A. Grucza, P. Salyer, S. M. Hartz, and L. J. Bierut

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Characterizing the Followers and Tweets of a Marijuana-Focused Twitter Handle, Patricia Cavazos-Rehg, Melissa Krauss, Richard Grucza, and Laura Bierut

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Beyond NK cells: the expanding universe of innate lymphoid cells, Marina Cella, Hannah Miller, and Christina Song

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Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop, Stefan Chabierski, Luisa Barzon, Anna Papa, Matthias Niedrig, Jonathan L. Bramson, Justin M. Richner, Giorgio Palu, Michael S. Diamond, and Sebastian Ulbert

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A comprehensive and high-resolution genome-wide response of p53 to stress, Gue Su Chang, Xiangyun Amy Chen, Bongsoo Park, Ho Sung Rhee, Pingxin Li, Kang Hoo Han, Tejaswini Mishra, Ka Yim Chan-Salis, Yunfei Li, Ross C. Hardison, Yanming Wang, and B. Franklin Pugh

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Reassessing the impact of smoking on preeclampsia/eclampsia: Are there age and racial differences?, Jen Jen Chang, Jerome F. Strauss III, Jon P. Deshazo, Fidelma B. Rigby, David P. Chelmow, and George A. Macones

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Targeting the programmed cell death 1: Programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis, Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, JoAnn Suzich, Jonathan Green, Andriani C. Patera, Wade Blair, Subramaniam Krishnan, and Richard Hotchkiss

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Cost-effectiveness of surgery and its policy implications for global health: A systematic review and analysis, Tiffany E. Chao, Ketan Sharma, Morgan Mandigo, Lars Hagander, Stephen C. Resch, Thomas G. Weiser, and John G. Meara

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Oral contraceptive use and mortality after 36 years of follow-up in the Nurses' Health Study: Prospective cohort study, Brittany M. Charlton, Janet W. Rich-Edwards, Graham A. Colditz, Stacey A. Missmer, Bernard A. Rosner, Susan E. Hankinson, Frank E. Speizer, and Karin B. Michels

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Pathogenic adaptations to host-derived antibacterial copper, Kaveri S. Chaturvedi and Jeffrey P. Henderson

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Conservative fluid therapy in septic shock: An example of targeted therapeutic minimization, Catherine Chen and Marin H. Kollef

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Copy number analysis of NIPBL in a cohort of 510 patients reveals rare copy number variants and a mosaic deletion, Yu-Wei Cheng, Christopher A. Tan, Agata Minor, Kelly Arndt, Latrice Wysinger, Dorothy K. Grange, Beth A. Kozel, Nathaniel H. Robin, Darrel Waggoner, Carrie Fitzpatrick, Soma Das, and Daniela del Gaudio

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Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice, Jianquan Chen, Yu Shi, Jenna Regan, Kannan Karuppaiah, David M. Ornitz, and Fanxin Long

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WNT7B promotes bone formation in part through mTORC1, Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M. Arbeit, Markus A. Ruegg, Michael N. Hall, Liang Ma, and Fanxin Long

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TIGRA: A targeted iterative graph routing assembler for breakpoint assembly, Ken Chen, Lei Chen, Xian Fan, John Wallis, Li Ding, and George Weinstock

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Rab5 isoforms orchestrate a ‘‘Division of Labor’’ in the endocytic network; Rab5C modulates Rac-mediated cell motility, Pin-I Chen, Kristine Schauer, Chen Kong, Andrew R. Harding, Bruno Goud, and Philip D. Stahl

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Joint testing of genotypic and gene-environment interaction identified novel association for BMP4 with non-syndromic CL/P in an Asian population using data from an International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, and Terri H. Beaty

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Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes, Shali Chen, Prasanth Puthanveetil, Biao Feng, Scot J. Matkovich, Gerald W. Dorn II, and Subrata Chakrabarti

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Patient-controlled epidural Levobupicvacaine with or without Fentanyl for post-cesarean section pain relief, Shin-Yan Chen, Feng-Lin Liu, Yih-Giun Cherng, Shou-Zen Fan, Barbara L. Leighton, Hung-Chi Chang, and Li-Kuei Chen

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Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila, Yun Chen, Megan Sparks, Poonam Bhandari, Scot J. Matkovich, and Gerald W. Dorn

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Chilling acclimation provides immunity to stress by altering regulatory networks and inducing genes with protective functions in Cassava, Zheng Chen, Jing Xia, Kevin Zhang, Weixiong Zhang, and et al

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A case study of risk factors for lymphatic filariasis in the Republic of Congo, Cédric B. Chesnais, François Missamou, Sébastien D. Pion, Jean Bopda, Frédéric Louya, Andrew C. Majewski, Peter U. Fischer, Gary J. Weil, and Michel Boussinesq

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Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect, Jaebok Choi, Matthew L. Cooper, Bader Alahmari, Julie Ritchey, Lynne Collins, Matthew Holt, and John F. DiPersio

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Effect of epigallocatechin-3-gallate on graft-versus-host disease, Jaebok Choi, Matthew L. Cooper, Edward D. Ziga, Julie Ritchey, and John F. DiPersio

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Dual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm–mosquito interactions, Young-Jun Choi, Matthew T. Aliota, George F. Mayhew, Sara M. Erickson, and Bruce M. Christensen

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Cervical spinal cord dimensions and clinical outcomes in adults with Klippel-Feil syndrome: A comparison with matched controls., Woojin Cho, Dong-Ho Lee, Joshua D. Auerbach, Jennifer K. Sehn, Colin E. Nabb, and K D. Riew

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GINDEL: Accurate genotype calling of insertions and deletions from low coverage population sequence reads, Chong Chu, Jin Zhang, and Yufeng Wu

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Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance, Jun-Jae Chung, Mary A. Markiewicz, Bojan Polic, and Andrey S. Shaw

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Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus, John R. Cirrito and et al

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Genetic variation in iron metabolism Is associated with neuropathic pain and pain severity in HIV-infected patients on antiretroviral therapy, David B. Clifford and et al.

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Allele-specific network reveals combinatorial interaction that transcends small effects in psoriasis GWAS, Sharlee Climer, Alan R. Templeton, and Weixiong Zhang

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Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations, Meghan A. Coghlan, Adrian Shifren, Howard J. Huang, Tonya D. Russell, Robi D. Mitra, Qunyuan Zhang, Daniel J. Wegner, F. Sessions Cole, and Aaron Hamvas

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Changes in medical errors after implementation of a handoff program, F. S. Cole and et al

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A mobile compression device for thombosis prevention in hip and knee arthroplasty, Clifford W. Colwell Jr., Mark I. Froimson, Scott D. Anseth, Nicholas J. Giori, William G. Hamilton, Robert L. Barrack, Knute C. Buehler, Michael A. Mont, Douglas E. Padgett, Pamela A. Pulido, and C. Lowery Barnes

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Telavancin for hospital-acquired pneumonia: Clinical response and 28-day survival, G. Ralph Corey, Marin H. Kollef, Andrew F. Shorr, Ethan Rubinstein, Martin E. Stryjewski, Alan Hopkins, and Steven L. Barriere

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Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia, David G. Cotter, Baris Ercal, Xiaojing Huang, Jamison M. Leid, Andre d'Avignon, Mark J. Graham, Dennis J. Dietzen, Elizabeth M. Brunt, Gary J. Patti, and Peter A. Crawford

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A brief overview of surgery for atrial fibrillation, James L. Cox

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Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease, Carlos Cruchaga, Alison M. Goate, and et al

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Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility, Lillian Cruz-Orengo, Brian P. Daniels, Denise Dorsey, Sarah Alison Basak, Jose G. Grajales-Reyes, Erin E. McCandless, Laura Piccio, Robert E. Schmidt, Anne H. Cross, Seth D. Crosby, and Robyn S. Klein

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Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees, Robert C. Culverhouse and et al

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Identifying cryptic population structure in multigenerational pedigrees in a Mexican American sample, Robert C. Culverhouse, Anthony L. Hinrichs, and Brian K. Suarez

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Practical barriers and ethical challenges in genetic data sharing, Rob Culverhouse and et al

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Construction and radiolabeling of adenovirus variants that incorporate human metallothionein into protein IX for analysis of biodistribution, David T. Curiel and et al

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Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals, Brian P. Daniels, David W. Holman, Lillian Cruz-Orengo, Harsha Jujjavarapu, Douglas M. Durrant, and Robyn S. Klein

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Participants’ perceptions of a group based program incorporating hands-on meal preparation and pedometer-based self-monitoring in type 2 diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, and Deborah Da Costa

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Shiga toxin/verocytotoxin-producing Escherichia coli infections: practical clinical perspectives, T. K. Davis, Nicole C.A. J. Van De Kar, and Phillip I. Tarr

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L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection, Lauren E. Deady, Elizabeth M. Todd, Chris G. Davis, Julie Y. Zhou, Nermina Topcagic, Brian T. Edelson, Thomas W. Ferkol, Megan A. Cooper, Jared T. Muenzer, and Sharon Celeste Morley