The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2013
Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy, James K. Ching and Conrad C. Weihl
A role for Ifit2 in restricting west nile virus infection in the brain, Hyelim Cho, Bimmi Shrestha, Ganes C. Sen, and Michael S. Diamond
Aspirin blocks EGF-stimulated cell viability in a COX-1 dependent manner in ovarian cancer cells, May Cho, Syeda M. Kabir, Yuanlin Dong, Eunsook Lee, Valerie Montgomery Rice, Dineo Khabele, and Deok-Soo Son
Vitamin D deficiency and prognostics among patients with pancreatic adenocarcinoma, May Cho, Parvin F. Peddi, Kevin Ding, Ling Chen, Denise Thomas, Jian Wang, Albert C. Lockhart, Benjamin Tan, and Andrea Wang-Gillam
RNase H2 roles in genome integrity revealed by unlinking its activities, Hyongi Chon, Justin L. Sparks, Monika Rychlik, Marcin Nowotny, Peter M. Burgers, Robert J. Crouch, and Susana M. Cerritelli
Global analysis of Drosophila Cys2-His2 zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants, Ryan G. Christensen, Gary D. Stormo, and et al
The effects of tetrahydrobiopterin (BH4) treatment on brain function in individuals with phenylketonuria, Shawn E. Christ, Amanda J. Moffitt, Dawn Peck, and Desiree A. White
Midkine mediates intercellular crosstalk between drug-resistant and drug sensitive neuroblastoma cells in vitro and in vivo, Fei Chu, Jessica A. Naiditch, Sandra Clark, Yi-Yong Qiu, Xin Zheng, Timothy B. Lautz, Janette L. Holub, Pauline M. Chou, Michael Czurylo, and Mary Beth Madonna
Fine-mapping an association of FSHR with preterm birth in a Finnish population, Sung Chun, Jevon Plunkett, Kari Teramo, Louis J. Muglia, and Justin C. Fay
Results of initial low-dose computed tomographic screening for lung cancer, Timothy R. Church, William C. Black, Denise R. Aberle, Christine D. Berg, Kathy L. Clingan, Fenghai Duan, Richard M. Fagerstrom, Ilana F. Gareen, David S. Gierada, Gordon C. Jones, Irene Mahon, Pamela M. Marcus, JoRean D. Sicks, Amanda Jain, and Sarah Baum
Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy, Sarah N. Cilvik, Joy I. Wang, Kory J. Lavine, Keita Uchida, Angela Castro, Carolyn M. Gierasch, Carla J. Weinheimer, Stacey L. House, Attila Kovacs, Colin G. Nichols, and David M. Ornitz
HIV DNA reservoir increases risk for cognitive disorders in cART-Naive patients, David B. Clifford and et al
Effect of daily chlorhexidine bathing on hospital-acquired infection, Michael W. Climo, Deborah S. Yokoe, David K. Warren, Trish M. Perl, Maureen Bolon, Loreen A. Herwaldt, Robert A. Weinstein, Kent A. Sepkowitz, John A. Jernigan, Kakotan Sanogo, and Edward S. Wong
Strategies and outcomes of HIV status disclosure in HIV-positive young women with abuse histories, Gretchen A. Clum, Lauren Czaplicki, Katherine Andrinopoulos, Kathryn Muessig, L Hamvas, and Jonathan M. Ellen
Onchocerciasis: The pre-control association between prevalence of palpable nodules and skin microfilariae, Luc E. Coffeng, Sebatien D. S. Pion, Simon O'Hanlon, Simon Cousens, Adenike O. Abiose, Peter U. Fischer, Jan H. F. Remme, K. Yankum Dadzie, Michele E. Murdoch, Sake J. de Vlas, Maria-Gloria Basanez, Wilma A. Stolk, and Michel Boussinesq
Reporting results: approaches have implications for prevention, Graham A. Colditz and Hank Dart
Histone methylation keeps the brakes on autophagy, Patrick L. Collins and Eugene M. Oltz
ATG5 regulates plasma cell differentiation, Kara L. Conway, Petric Kuballa, Bernard Khor, Mei Zhang, Hai Ning Shi, Herbert W. Virgin, and Ramnik J. Xavier
Quality assurance of radiotherapy in the ongoing EORTC 22042–26042 trial for atypical and malignant meningioma: Results from the dummy runs and prospective individual case Reviews, Mehtap Coskun, William Straube, Coen W. Hurkmans, Christos Melidis, Patricia F. de Haan, Salvador Villa, Sandra Collette, and Damien C. Weber
Mechanisms of chronic cardiac allograft rejection, J P. Costello, T Mohanakumar, and D S. Nath
Fecal microbiota diversity in survivors of adolescent/young adult Hodgkin lymphoma: A study of twins, Wendy Cozen, Guoqin Yu, Mitchell H. Gail, Vanessa K. Ridaura, Bharat N. Nathwani, Amie E. Hwang, Ann S. Hamilton, Thomas M. Mack, Jeffrey I. Gordon, and James J. Goedert
Alcohol-induced apoptosis of oligodendrocytes in the fetal macaque brain, Catherine E. Creeley, Krikor T. Dikranian, Stephen A. Johnson, Nuri B. Farber, and John W. Olney
Drug-induced apoptosis: Mechanism by which alcohol and many other drugs can disrupt brain development, Catherine E. Creeley and John W. Olney
Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells, Monica Croke, Martin A. Neumann, David A. Grotsky, Ray Kreienkamp, Sree C. Yaddanapudi, and Susana Gonzalo
Genomic sequence diversity and population structure of Saccharomyces cerevisiae assessed by RAD-seq, Gareth A. Cromie, Katie E. Hyma, Catherine L. Ludlow, Cecilia Garmendia-Torres, Teresa L. Gilbert, Patrick May, Angela A. Huang, Aimee M. Dudley, and Justin C. Fay
TREM2 variants in Alzheimer's disease, Carlos Cruchaga, Bruno Benitez, Breanna Cooper, David Carrell, Yefei Cai, John C. Morris, Alison Goate, and et al
A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components, Jessica Cruz de Leon, Nicole Scheumann, Wandy Beatty, Josh R. Beck, Johnson Q. Tran, Candace Yau, Peter J. Bradley, Keith Gull, Bill Wickstead, and Naomi S. Morrissette
Mechanisms of hypoglycemia-associated autonomic failure in diabetes, Philip E. Cryer
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression, Robert C. Culverhouse; Lucy Bowes; Naomi Breslau; John I. Nurnberger Jr.; Margit Burmeister; David M. Fergusson; Marcus Munafo; Nancy L. Saccone; Laura J. Bierut; and 5-HTTLPR, Stress, and Depression Consortium
Adaptive evolution of the Streptococcus pyogenes regulatory aldolase LacD.1, Zachary Cusumano and Michael Caparon
Why are spine surgery patients lost to follow-up?, Scott D. Daffner, Alan S. Hilibrand, and K. D. Riew
Using Small-Area Analysis to Estimate County-Level Racial Disparities in Obesity Demonstrating the Necessity of Targeted Interventions, Lucy D'Agostino-McGowan, Renee L. Gennarelli, Sarah A. Lyons, and Melody S. Goodman
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation, Jasbir Dalal, Jee Hoon Roh, Susan E. Maloney, Afua Akuffo, Samir Shah, Han Yuan, Brie Wamsley, Wendell B. Jones, Cristina de Guzman Strong, Paul A. Gray, David M. Holtzman, Nathaniel Heintz, and Joseph D. Dougherty
An emerging place for lung cancer genomics in 2013, Marissa G. Daniels, Rayleen V. Bowman, Ian A. Yang, Ramaswamy Govindan, and Kwun M. Fong
Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability, Arindam Das, David A. Grotsky, Martin A. Neumann, Ray Kreienkamp, Ignacio Gonzalez-Suarez, Abena B. Redwood, Brian K. Kennedy, Colin L. Stewart, and Susana Gonzalo
Differential lipid dependence of the function of bacterial sodium channels, Nazzareno D'Avanzo, Emily C. McCusker, Andrew M. Powl, Andrew J. Miles, Colin G. Nichols, and B. A. Wallace
mBLAST: Keeping up with the sequencing explosion for (meta) genome analysis, Curtis Davis, Karthik Kota, Venkat Baldhandapani, Wei Gong, Sahar Abubucker, Eric Becker, John Martin, Kristine M. Wylie, Radhika Khetani, Matthew E. Hudson, George M. Weinstock, and Makedonka Mitreva
Aggressive blood pressure control for chronic kidney disease unmasks moyamoya!, T. Keefe Davis, Carmen M. Halabi, Philp Siefken, Swati Karmarkar, and Jeffrey Leonard
An agent-based modeling template for a cohort of veterans with diabetic retinopathy, Theodore Eugene Day, Nathan Ravi, Hong Xian, and Ann Brugh
Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations, Gustavo Deco, Adrian Ponce Alvarez, Dante Mantini, Gian Luca Romani, Patric Hagmann, and Maurizio Corbetta
Characterization of the mechanical strength, resorption properties, and histologic characteristics of a fully absorbable material (poly-4-hydroxybutyrate-PHASIX mesh) in a porcine model of hernia repair, Corey R. Deeken and Brent D. Matthews
Ventralight ST and Sorbafix versus Physiomesh and Securestrap in a porcine model, Corey R. Deeken and Brent D. Matthews
Cone phosphodiesterase-6α′ restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse, Wen-Tao Deng, Keisuke Sakurai, Saravanan Kolandaivelu, Alexander V. Kolesnikov, Astra Dinculescu, Jie Li, Ping Zhu, Xuan Liu, Jijing Pang, Vince A. Chiodo, Sanford L. Boye, Bo Chang, Visvanathan Ramamurthy, Vladimir J. Kefalov, and William W. Hauswirth
Evolutionary genomics of the Salmonella enterica subspecies, Prerak T. Desai, Steffen Porwollik, Fred Long, Pui Cheng, Aye Wollam, Sandra W. Clifton, George M. Weinstock, and Michael McClelland
Genomic and metabolic disposition of non-obese Type 2 Diabetic rats to increased myocardial fatty acid metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, and Kooresh I. Shoghi
Antisense reduction of tau in adult mice protects against seizures, Sarah L. DeVos, Dustin K. Goncharoff, Guo Chen, Carey S. Kebodeaux, Kaoru Yamada, Floy R. Stewart, Dorothy R. Schuler, Susan E. Maloney, David F. Wozniak, Frank Rigo, C Frank Bennett, John R. Cirrito, David M. Holtzman, and Timothy M. Miller
Association of gut microbiota with post-operative clinical course in Crohn’s disease, Neelendu Dey, David AW Soergel, Susanna Repo, and Steven E. Brenner
Control of cellular Bcl-xL levels by deamidation-regulated degradation, So Hee Dho, Benjamin E. Deverman, Carlo Lapid, Scott R. Manson, Lu Gan, Jacob J. Riehm, Rajeev Aurora, Ki-Sun Kwon, and Steven J. Weintraub
How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity, Danielle M. Dick, Fazil Aliev, Shawn Latendresse, Bernice Porjesz, Marc Schuckit, Madhavi Rangaswamy, Victor Hesselbrock, Howard Edenberg, John Nurnberger Jr., Arpana Agrawal, Laura Bierut, Jen Wang, Kathy Bucholz, Samuel Kuperman, and John Kramer
Point-of-Care glucose analysis in neonates using modified quinoprotein glucose dehydrogenase, Dennis J. Dietzen, Timothy R. Wilhite, Maynard Rasmussen, and Mark Sheffield
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias, J. DiPersio and et al
Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I, John F. DiPersio and et al
Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data, Nico U.F. Dosenbach, Bradley L. Schlaggar, and et al
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, and Nathaniel Heintz
Body temperature patterns as a predictor of hospital-acquired sepsis in afebrile adult intensive care unit patients: A case-control study, Anne M. Drewry, Brian M. Fuller, Thomas C. Bailey, and Richard S. Hotchkiss
Counting unstained, confluent cells by modified bright-field microscopy, L. Louis Drey, Michael Graber, and Jan Bieschke
Transtibial ACL femoral tunnel preparation increases odds of repeat ipsilateral knee surgery, Andrew Duffee, Rober A. Magnussen, Angela D. Pedroza, David C. Flanigan, MOON Group, et al, Rick W. Wright, Matthew J. Matava, and Robert H. Brophy
Soluble oligomers are sufficient for transmission of a yeast prion but do not confer phenotype, Jennifer E. Dulle, Rachel E. Bouttenot, Lisa A. Underwood, and Heather L. true
Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants, Jennifer E. Dulle and Heather L. true
Genome sequences of three hpAfrica2 strains of Helicobacter pylori, Stacy S. Duncan, M Teresita Bertoli, Dangeruta Kersulyte, Pieter L. Valk, Sravya Tamma, Issy Segal, Mark S. McClain, Timothy L. Cover, and Douglas E. Berg
IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis, Douglas M. Durrant, Michelle L. Robinette, and Robyn S. Klein
Weekend diagnosis of Escherichia coli urinary tract infection does not predict poor outcome, J. F. Echaiz, J. P. Henderson, D. K. Warren, and J. Marschall
Physiological role of the interaction between CARMIL1 and capping protein, Marc Edwards, Yun Liang, Taekyung Kim, and John A. Cooper
The relationship between resilience and personality traits in doctors: Implications for enhancing well being, Diane S. Eley, C. Robert Cloninger, Lucie Walters, Caroline Laurence, Robyn Synnott, and David Wilkinson
ZRT1 harbors an excess of nonsynonymous polymorphism and shows evidence of balancing selection in Saccharomyces cerevisiae, Elizabeth K. Engle and Justin C. Fay
RNA helicase signaling is critical for type I interferon production and protection against rift valley fever virus during mucosal challenge, Megan E. Ermler, Ekaterina Yerukhim, Jill Schriewer, Stefan Schattgen, Zachary Traylor, Adam R. Wespiser, Daniel R. Caffrey, Zhijian J. Chen, Charles H. King, Michael Gale Jr., Marco Colonna, Katherine A. Fitzgerald, R. Mark L. Buller, and Amy G. Hise
The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling west nile virus infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, and Michael Gale Jr
HIV-Infected Adolescent, Young Adult and Pregnant Smokers: Important Targets for Effective Tobacco Control Programs, Gerome Escota and Nur Önen
Katanin localization requires triplet microtubules in Chlamydomonas reinhardtii, Jessica M. Esparza, Eileen O'Toole, Linya Li, Thomas H. Giddings Jr., Benjamin Kozak, Alison J. Albee, and Susan K. Dutcher
Retrotransposition of gene transcripts leads to structural variation in mammalian genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing and Analysis Program and Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, and David Haussler
Myocardial ablation of G protein–coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion injury through an anti-intrinsic apoptotic pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn II, Walter J. Koch, and Erhe Gao
Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials, Austin M. Faught, Stephen F. Kry, Dershan Luo, Andrea Molineu, David Bellezza, Russel L. Gerber, Scott E. Davidson, Walter Bosch, Robert E. Drzymala, Jim Galvin, Robert Timmerman, Jason Sheehan, Michael T. Gillin, Geoffrey S. Ibbot, and David S. Followill
Disease consequences of human adaptation, Justin C. Fay
Control the host cell cycle: Viral regulation of the anaphase-promoting complex, Anthony R. Fehr and Dong Yu
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province, and et al
Changes in auditory perceptions and cortex resulting from hearing recovery after extended congenital unilateral hearing loss, Jill B. Firszt, Ruth M. Reeder, Timothy A. Holden, Harold Burton, and Richard A. Chole
Serological diagnosis of North American paragonimiasis by western blot using Paragonimus kellicotti adult worm antigen, Peter U. Fischer, Kurt C. Curtis, Scott M. Folk, Patricia P. Wilkins, Luis A. Marcos, and Gary J. Weil
Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration: A multicenter evaluation, Peter U. Fischer, Ramakrishna U. Rao, and et al
Acute care costs in overweight children: a pediatric urban cohort study, Katherine E. Fleming-Dutra, Jingnan Mao, and Julie C. Leonard
Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, and Roberto Pili
Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper, Bradley A. Ford and Carey-Ann D. Burnham
AhrC and Eep are biofilm infection-associated virulence factors in enterococcus faecalis, Kristi L. Frank, Pascale S. Guiton, Aaron M T Barnes, Dawn A. Manlas, Olivia N. Chuang-Smith, Petra L. Kohler, Adam R. Spaulding, Scott J. Hultgren, Patrick M. Schievert, and Gary M. Dunny
Targeted versus universal decolonization to prevent ICU infection, Victoria J. Fraser and et al
Depression as a risk factor for adverse outcomes in coronary heart disease, Kenneth E. Freedland and Robert M. Carney
Mupirocin and chlorhexidine resistance in Staphylococcus aureus in patients with community-onset skin and soft tissue infections, Stephanie A. Fritz, Patrick G. Hogan, Bernard C. Camins, Ali J. Ainsworth, Carol Patrick, Madeline S. Martin, Melissa J. Krauss, Marcela Rodriguez, and Carey-Ann D. Burnham
Digit Replantation: Experience of two U.S. academic level-I trauma centers, Duretti Fufa, Ryan Calfee, Lindley Wall, Wenjing Zeng, and Charles Goldfarb
Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: A systematic review, Brian M. Fuller, Nicholas M. Mohr, Anne M. Drewry, and Christopher R. Carpenter
Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, and Robert O. Heuckeroth
Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling, Katsuhiko Funai, Haowei Song, Li Yin, Irfan J. Lodhi, Xiaochao Wei, Jun Yoshino, Trey Coleman, and Clay F. Semenkovich
A pharmacogenetic versus a clinical algorithm for warfarin dosing, Brian F. Gage, Charles S. Eby, and et al
Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA, Roberto Galletto and Eric J. Tomko
To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed, Barbara Gandolfi, Hasan Alhaddad, Verena K. Affolter, Jeffrey Brockman, Jens Haggstrom, Shannon E. K. Joslin, Amanda L. Koehne, James C. Mullikin, Catherine A. Outerbridge, Wesley C. Warren, and Leslie A. Lyons
Esophageal sphincter device for gastroesophageal reflux disease, Robert A. Ganz, Jeffrey H. Peters, Santiago Horgan, Willem A. Bemelman, Christy M. Dunst, Steven A. Edmundowicz, John C. Lipham, James D. Luketich, W. Scott Melvin, Brant K. Oelschlager, Steven C. Schlack-Haerer, C. Daniel Smith, Christopher C. Smith, Dan Dunn, and Paul A. Taiganides
Temperament and character in the Child and Adolescent Twin Study in Sweden (CATSS): Comparison to the general population, and genetic structure analysis, Danilo Garcia, Sebastian Lundstrom, Sven Brandstrom, Maria Rastam, C. Robert Cloninger, Nora Kerekes, Thomas Nilsson, and Henrik Anckarsater
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, and Laurent Yvan-Charvet
Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications, Hiram A. Gay, Quendella Q. Taylor, Fumika Kiriyama, Geoffrey T. Dieck, Todd Jenkins, Paul Walker, Ron R. Allison, and Paolo Ubezio
Sarm1-mediated axon degeneration requires both SAM and TIR interactions, Josiah Gerdts, Daniel W. Summers, Yo Sasaki, Aaron DiAntonio, and Jeffrey Milbrandt
Adrenal myelolipoma: Operative indications and outcomes, Victoria M. Gershuni, James G. Bittner IV, Jeffrey F. Moley, and L. Michael Brunt
The quest for load‐independent left ventricular chamber properties: Exploring the normalized pressure phase plane, Erina Ghosh and Sandor J. Kovacs
Training the workforce in evidence-based public health: An evaluation of impact among US and international practitioners, Wesley S. Gibbert, Shannon M. Keating, Julie A. Jacobs, Elizabeth Dodson, Elizabeth Baker, Gunter Diem, Wayne Giles, Kathleen N. Gillespie, Vilius Grabauskas, Aushra Shatchkute, and Ross C. Brownson
