The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2014

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Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese, Charles Gu, Treva K. Rice, Dabeeru C. Rao, and et al

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Isoprenoid Biosynthesis in Plasmodium falciparum, Ann M. Guggisberg, Rachel E. Amthor, and Audrey R. Odom

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A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites, Ann M. Guggisberg, Jooyoung Park, Rachel L. Edwards, Megan L. Kelly, Dana M. Hodge, Niraj H. Tolia, and Audrey R. Odom

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Sequence specificity incompletely defines the genome-wide occupancy of Myc, Jiannan Guo, Tiandao Li, Joshua Schipper, Kyle A. Nilson, Francis K. Fordjour, Jeffrey J. Cooper, Raluca Gordan, and David H. Price

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Over-expression of TRESK K(+) channels reduces the excitability of trigeminal ganglion nociceptors, Zhaohua Guo and Yu-Qing Cao

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An improved predictive recognition model for Cys2-His2 zinc finger proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J Keith Joung, Scot A. Wolfe, and Gary D. Stormo

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MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice, Arun Gupta, Clayton R. Hunt, Nobuo Horikoshi, Raj K. Pandita, Tej K. Pandita, and et al

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Localizing ECoG electrodes on the cortical anatomy without post-implantation imaging, Disha Gupta, N. Jeremy Hill, Matthew A. Adamo, Anthony Ritaccio, and Gerwin Schalk

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BMPRIA mediated signaling is essential for temporomandibular joint development in mice, Shuping Gu, Weijie Wu, Chao Liu, Ling Yang, Cheng Sun, Wenduo Ye, Xihai Li, Jianquan Chen, Fanxin Long, and YiPing Chen

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The taxonomy of brain cancer stem cells: What's in a name?, David H. Gutmann

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Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: Pro-survival role of Ambra1, Wen Gu, Daiwei Wan, Qinyi Qian, Bin Yi, Zhilong He, Yilin Gu, Liang Wang, and Songbing He

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Association of atypical femoral fractures with bisphosphonate use by patients with varus hip geometry, Jennifer E. Hagen, Anna N. Miller, Susan M. Ott, Michael Gardner, Saam Morshed, Kyle Jeray, Timothy B. Alton, Dennis Ren, W. Parker Abblitt, and James C. Krieg

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Evaluation of a real-time PCR assay for simultaneous detection of Kingella kingae and Staphylococcus aureus from synovial fluid in suspected septic arthritis, Malay Haldar, Meghan A. Butler, Criziel D. Quinn, Charles W. Stratton, Yi-Wei Tang, and Carey-Ann D. Burnham

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Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior, Gabe Haller, Ping Li, Caroline Esch, Simon Hsu, Alison M. Goate, and Joe Henry Steinbach

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Inhibition of cyclooxygenase-2 prevents chronic and recurrent cystitis, Thomas J. Hannan, Terrence E. Riehl, Jana M. Binkley, Drew J. Schwartz, Hiroyuki Miyoshi, Thaddeus S. Stappenbeck, William F. Stenson, Marco Colonna, Scott J. Hultgren, and et al

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BioPen: direct writing of functional materials at the point of care, Yu Long Han, Jie Hu, Guy M. Genin, Tian Jian Lu, and Feng Xu

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Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, and Daniel E.L. Promislow

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Gender differences in outcomes of patients with cystic fibrosis, Cayce L. Harness-Brumley, Alan C. Elliot, Daniel B. Rosenbluth, Deepa Raghavan, and Raksha Jain

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Bony abnormalities of the hip joint: a new comprehensive, reliable and radiation-free measurement method using magnetic resonance imaging, Marcie Harris-Hayes, Paul K. Commean, Jacqueline D. Patterson, John C. Clohisy, and Travis J. Hillen

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Relative mortality in U.S. Medicare beneficiaries with Parkinson disease and hip and pelvic fractures, Marcie Harris-Hayes, Allison W. Willis, Sandra E. Klein, Sylvia Czuppon, Beth Crowner, and Brad A. Racette

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Information-seeking among chronic disease prevention staff in state health departments: Use of academic journals, Jenine K. Harris, Peg Allen, Rebekah R. Jacob, Lindsay Elliott, and Ross C. Brownson

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Ureteral stent placement increases the risk for developing BK viremia after kidney transplantation., Faris Hashim, Shehzad Rehman, Jon A. Gregg, and Vikas R. Dharnidharka

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Circadian rhythm reprogramming during lung inflammation, Jeffrey A. Haspel and et al

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A critical review of the role of local excision in the treatment of early (T1 and T2) rectal tumors, Thomas A. Heafner and Sean C. Glasgow

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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis, Andrew C. Heath and Pamela A. F. Madden

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Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus, Junyun He, Huafang Lai, Michael Engle, Sergey Gorlatov, Clemens Gruber, Herta Steinkellner, Michael S. Diamond, and Qiang Chen

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Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging, Harvey Hensley, Karthik Devarajan, James R. Johnson, David Piwnica-Worms, Andrew K. Godwin, Margaret von Mehren, and Lori Rink

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Data dictionary services in XNAT and the Human Connectome Project, Rick Herrick, Michael McKay, Timothy Olsen, William Horton, Mark Florida, Charles J. Moore, and Daniel S. Marcus

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Thermomechanical fatigue life prediction for a marine diesel engine piston considering ring dynamics, Tao He, Xiqun Lu, Dequan Zou, Yibin Guo, Wanyou Li, and Minli Huang

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Some personal and historical notes on the utility of "deep-etch" electron microscopy for making cell structure/function correlations, John E. Heuser

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Genotypic discrepancies arising from imputation, Anthony L. Hinrichs, Robert C. Culverhouse, and Brian K. Suarez

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Efficacy of once-daily extended-release topiramate (USL255): A subgroup analysis based on the level of treatment resistance, R. Edward Hogan, Ilan Blatt, Balduin Lawson, Venkatesh Nagaraddi, Toufic A. Fakhoury, Bob Anders, Annie M. Clark, Dawn Laine, Mark B. Halvorsen, and Steve S. Chung

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Seroepidemiology of astrovirus MLB1, Lori R. Holtz, Irma K. Bauer, Hongbing Jiang, Robert Belshe, Pamela Freiden, Stacey L. Schultz-Cherry, and David Wang

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Genome-wide association study of Arabidopsis thaliana leaf microbial community, Matthew W. Horton, Natacha Bodenhausen, Kathleen Beilsmith, Dazhe Meng, Brian D. Muegge, Sathish Subramanian, M. Madlen Vetter, Bjarni J. Vilhjálmsson, Magnus Nordborg, Jeffrey I. Gordon, and Joy Bergelson

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Parallels between cancer and infectious disease, Richard S. Hotchkiss and Lyle L. Moldawer

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The kidney tight junction, Jianghui Hou

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Landscape of target: Guide homology effects on Cas9-mediated cleavage, Becky Xu Hua Fu, Loren L. Hansen, Karen L. Artiles, Michael L. Nonet, and Andrew Z. Fire

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Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma, Yin-Cheng Huang, Kuo-Chen Wei, Chen-Nen Chang, Pin-Yuan Chen, Peng-Wei Hsu, Carl P. Chen, Chin-Song Lu, Hung-Li Wang, David H. Gutmann, and Tu-Hsueh Yeh

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Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing, Andrew E. O. Hughes, Vincent Magrini, Ryan Demeter, Christopher A. Miller, Robert Fulton, Lucinda L. Fulton, William C. Eades, Kevin Elliott, Sharon Heath, Peter Westervelt, Li Ding, Donald F. Conrad, Brian S. White, Jin Shao, Daniel C. Link, John F. DiPersio, Elaine R. Mardis, Richard K. Wilson, Timothy J. Ley, Matthew J. Walter, and Timothy A. Graubert

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The bacterial amyloid curli Is associated with urinary source bloodstream infection, Chia Hung, Jonas Marschall, Carey-Ann D. Burnham, Albert S. Byun, and Jeffrey P. Henderson

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Draft genome sequence of Acetobacter aceti strain 1023, a vinegar factory isolate, John E. Hung, Christopher P. Mill, Sandra W. Clifton, Vincent Magrini, Ketaki Bhide, Julie A. Francois, Aaron E. Ransome, Lucinda Fulton, Jyothi Thimmapuram, Richard K. Wilson, and T. Joseph Kappock

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Roles of ON cone bipolar cell subtypes in temporal coding in the mouse retina, Tomomi Ichinose, Bozena Fyk-Kolodziej, and Jesse Cohn

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Neurologic abnormalities in mouse models of the lysosomal storage disorders mucolipidosis II and mucolipidosis III γ, Rachel A. Idol, David F. Wozniak, Hideji Fujiwara, Carla M. Yuede, Daniel S. Ory, Stuart Kornfeld, and Peter Vogel

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A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer, Joseph E. Ippolito and David Piwnica-Worms

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Stress mediates the relationship between sexual orientation and behavioral risk disparities, Jennifer M. Jabson, Grant W. Farmer, and Deborah J. Bowen

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Training needs and supports for evidence-based decision making among the public health workforce in the United States, Rebekah R. Jacob, Elizabeth A. Baker, Peg Allen, Elizabeth A. Dodson, Kathleen Duggan, Robert Fields, Sonia Sequeira, and Ross C. Brownson

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Capacity building for evidence-based decision making in local health departments: Scaling up an effective training approach, Julie A. Jacobs, Kathleen Duggan, Paul Erwin, Carson Smith, Elaine Borawski, Judy Compton, Luann D'Ambrosio, Scott H. Frank, Susan Frazier-Kouassi, Peggy A. Hannon, Jennifer Leeman, Avia Mainor, and Ross C. Brownson

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Acceptability of, and willingness to pay for, community health insurance in rural India, Ankit Jain, Selva Swetha, Zeena Johar, and Ramesh Raghavan

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Nanoparticle incorporation of melittin reduces sperm and vaginal epithelium cytotoxicity, Andrew P. Jallouk, Kelle H. Moley, Kenan Omurtag, Grace Hu, Gregory M. Lanza, Samuel A. Wickline, and Joshua L. Hood

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Identification of pathologic features associated with “ulcerative colitis-like” Crohn’s disease, Samuel D. James, Paul E. Wise, Tania Zuluaga-Toro, David A. Schwartz, M. Kay Washington, and Chanjuan Shi

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Bicuspid pulmonic valve and pulmonary artery aneurysm, Carlos Jamis-Dow, George Barbier, Mary Watkins, Gregory Lanza, Shelton Caruthers, and Samuel Wickline

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Engineering recombinant orsay virus directly in the metazoan host Caenorhabditis elegans, Hongbing Jiang, Carl J. Franz, and David Wang

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Relative acidic compartment volume as a lysosomal storage disorder-associated biomarker, Xuntian Jiang, Rohini Sidhu, Daniel S. Ory, Danielle te Vruchte, Anneliese O. Speak, Kerri L. Wallom, Nada Al Eisa, David A. Smith, Christian J. Hendriksz, Louise Simmons, Robin H. Lachmann, Alison Cousins, Ralf Hartung, Eugen Mengel, and et al.

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Wnt7b can replace Ihh to induce hypertrophic cartilage vascularization but not osteoblast differentiation during endochondral bone development, Kyu Sang Joeng and Fanxin Long

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Uncovering the components of the Francisella tularensis virulence stealth strategy, Bradley D. Jones, Matthew Faron, Jed A. Rasmussen, and Joshua R. Fletcher

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Healthy weight regulation and eating disorder prevention in high school students: A universal and targeted web-based intervention, Megan Jones, Katherine T. Lynch, Andrea E. Kass, Amanda Burrows, Joanne W. Williams, Denise E. Wilfley, and Craig B. Taylor

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Compressed sampling strategies for tomography, Yan Kaganovsky, Daheng Li, Andrew Holmgren, HyunJu Jeon, Kenneth P. MacCabe, David G. Politte, Joseph A. O'Sullivan, Lawrence Carin, and David J. Brady

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Contaminated heparin and outcomes after cardiac surgery: A retrospective propensity-matched cohort study, Heiko A. Kaiser, Arbi Ben Abdallah, Nan Lin, Bethany R. Tellor, Mohammad Helwani, Jennifer R. Smith, Marc R. Moon, and Michael S. Avidan

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Anatomic determinants of sacral dysmorphism and implications for safe iliosacral screw placement, Scott P. Kaiser, Michael J. Gardner, Joseph Liu, M. L. Chip Routt Jr., and Saam Morshed

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Integrated analysis of germline and somatic variants in ovarian cancer, Krishna L. Kanchi, Kimberly J. Johnson, Charles Lu, Michael D. McLellan, Michael C. Wendl, Qunyuan Zhang, Daniel C. Koboldt, Mingchao Xie, Cyriac Kandoth, Joshua F. McMichael, Matthew A. Wyczalkowski, David E. Larson, Heather K. Schmidt, Christopher A. Miller, Robert S. Fulton, Elaine R. Mardis, Todd E. Druley, Timothy A. Graubert, Richard K. Wilson, Li Ding, and et al

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Effects of patient health literacy, patient engagement and a system-level health literacy attribute on patient-reported outcomes: A representative statewide survey, Kimberly A. Kaphingst, Nancy L. Weaver, Ricardo J. Wray, Melissa LR Brown, Trent Buskirk, and Matthew W. Kreuter

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Genome-wide association study of CSF levels of 59 Alzheimer’s disease candidate proteins: Significant associations with proteins involved in amyloid processing and inflammation, Celeste M. Karch, Oscar Harari, Carlos Cruchaga, Benjamin J. Ainscough, Sarah Bertlesen, Anne M. Fagan, David M. Holtzman, John C. Morris, Alison M. Goate, and et al

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Somatostatin analogues for receptor targeted photodynamic therapy, Slavka Kascakova, Leo J. Hofland, Henriette S. De Bruijn, Yunpeng Ye, Samuel Achilefu, Katy van der Wansem, Angelique van der Ploeg-van den Heuvel, Peter M. van Koetsveld, Michael P. Brugts, Aart-Jan van der Lelij, Henricus J. C. M. Strerenborg, Timo L. M. ten Hagen, Dominic J. Robinson, and Martin P. van Hagen

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Rehabilitation following arthroscopic rotator cuff repair: A prospective randomized trial of immobilization compared with early motion, Jay D. Keener, Leesa M. Galatz, Georgia Stobbs-Cucchi, Rebecca Patton, and Ken Yamaguchi

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A prospective evaluation of survivorship of asymptomatic degenerative rotator cuff tears, Jay D. Keener, Leesa M. Galatz, Sharlene A. Teefey, William D. Middleton, Karen Steger-May, Georgia Stobbs-Cucchi, Rebecca Patton, and Ken Yamaguchi

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Propofol and sevoflurane induce distinct burst suppression patterns in rats, Jonathan D. Kenny, M. Brandon Westover, ShiNung Ching, Emery N. Brown, and Ken Solt

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Current surgical treatment strategies for hepatocellular carcinoma in North America, Adeel S. Khan, Kathryn J. Fowler, and William C. Chapman

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Geographic separation of domestic and wild strains of Toxoplasma gondii in French Guiana correlates with a monomorphic version of chromosome1a, Asis Khan, Daniel Ajzenberg, Aurelien Mercier, Magalie Demar, Stephane Simon, Marie Laure Darde, Qiuling Wang, Shiv Kumar Verma, Benjamin M. Rosenthal, Jitender P. Dubey, and L. David Sibley

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NextGen sequencing reveals short double crossovers contribute disproportionately to genetic diversity in Toxoplasma gondii, Asis Khan, Jahangheer S. Shaik, Michael Behnke, Qiuling Wang, Jitender P. Dubey, Hernan A. Lorenzi, James W. Ajioka, Benjamin M. Rosenthal, and L. David Sibley

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Complete absence of the posterior arch of C1: Case report, R. Khanna, Z. A. Smith, B. J. Dlouhy, and N. S. Dahdaleh

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International Radical Cystectomy Consortium: A way forward, Adam S. Kibel and et al.

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Acute cell viability and nitric oxide release in lateral menisci following closed-joint knee injury in a lapine model of post-traumatic osteoarthritis, Megan L. Killian, Roger C. Haut, and Tammy L. Haut Donahue

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SigFuge: Single gene clustering of RNA-seq reveals differential isoform usage among cancer samples, Patrick K. Kimes, Christopher R. Cabanski, Matthew D. Wilkerson, Ni Zhao, Amy R. Johnson, Charles M. Perou, Liza Makowski, Christopher A. Maher, Yufeng Liu, J. S. Marron, and D. Neil Hayes

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TrkB agonist antibody pretreatment enhances neuronal survival and long-term sensory motor function following hypoxic ischemic injury in neonatal rats, Gab Seok Kim, Seongeun Cho, James W. Nelson, Gregory J. Zipfel, and Byung Hee Han

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Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem, Ji-Young Kim, Ana Kim, Zhong-Qiu Zhou, Xian-Yu Liu, and Zhou-Feng Chen

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Systematic shifts in the balance of excitation and inhibition coordinate the activity of axial motor pools at different speeds of locomotion, Sandeep Kishore, Martha W. Bagnall, and David L. McLean

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Impact of host age and parity on susceptibility to severe urinary tract infection in a murine model, Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, and Amanda L. Lewis

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Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci, Daniel C. Koboldt, David E. Larson, Qunyuan Zhang, Ling Lin, Li Ding, Michael D. McLellan, Michele O'Laughlin, Catrina Fronick, Lucinda L. Fulton, Vincent Magrini, Robert S. Fulton, Richard K. Wilson, and et al

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Effect of home telemonitoring on glycemic and blood pressure control in primary care clinic patients with diabetes, Richelle J. Koopman, Bonnie J. Wakefield, Jennifer L. Johanning, Lynn E. Keplinger, Robin L. Kruse, Marilee Bomar, Beth Bernt, Douglas S. Wakefield, and David R. Mehr

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Is the relationship between binge eating episodes and personality attributable to genetic factors?, Rachel Koren, Melissa A. Munn-Chernoff, Alexis E. Duncan, Kathleen K. Bucholz, Pamela A.F. Madden, Andrew C. Heath, and Arpana Agrawal

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Stealth nanotubes: strategies of shielding carbon nanotubes to evade opsonization and improve biodistribution, Nalinikanth Kotagiri and Jin-Woo Kim

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The prevalence of species and strains in the human microbiome: A resource for experimental efforts, Laurens Kraal, Sahar Abubucker, Karthik Kota, Michael A. Fischbach, and Makedonka Mitreva

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Establishing the need and identifying goals for a curriculum in medical business ethics: A survey of students and residents at two medical centers in Missouri, Elena M. Kraus, Erin Bakanas, Kamal Gursahani, and James M. DuBois

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Dynamometer-based measure of spasticity confirms limited association between plantarflexor spasticity and walking function in persons with multiple sclerosis, Theodore R. Kremer, Linda R. Van Dillen, and Joanne M. Wagner

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Fast phasic release properties of dopamine studied with a channel biosensor, Geraaldine J. Kress, Hong-Jin Shu, Andrew Yu, Amanda Taylor, Ann Benz, Steve Harmon, and Steven Mennerick

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Central memory CD8+ T lymphocytes mediate lung allograft acceptance, Alexander Sasha Krupnick, Xue Lin, Wenjun Li, Ryuiji Higashikubo, Bernd H. Zinselmeyer, Hollyce Hartzler, Kelsey Toth, Jon H. Ritter, Mikhail Y. Berezin, Steven T. Wang, Mark J. Miller, Andrew E. Gelman, and Daniel Kreisel

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IL-6 stimulates intestinal epithelial proliferation and repair after injury, Kristine A. Kuhn, Nicholas A. Manieri, Ta-Chiang Liu, and Thaddeus S. Stappenbeck

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Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan, Alexander M. Kulminski, Konstantin G. Arbeev, Irina Culminskaya, Liubov Arbeeva, Svetlana V. Ukraintseva, Eric Stallard, Kaare Christensen, Nicole Schupf, Michael A. Province, and Anatoli I. Yashin

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Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly, Pardeep Kumar, Christian Heiss, Felipe H. Santiago-Tirado, Ian Black, Parastoo Azadi, and Tamara L. Doering

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Eata, an immunogenic protective antigen of enterotoxigenic Escherichia coli, degrades intestinal mucin, Pardeep Kumar, Qingwei Luo, Tim J. Vickers, Alaullah Sheikh, and James M. Fleckenstein

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Keep on laying eggs mama, RNAi my reproductive aging blues away, Sandeep Kumar, Zuzana Kocsisova, and Kerry Kornfeld

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The transcriptome of utricle hair cell regeneration in the avian inner ear, Yuan-Chieh Ku, Nicole A. Renaud, Rose A. Veile, Cynthia Helms, Courtney C J Voelker, Mark E. Warchol, and Michael Lovett

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High-throughput functional testing of ENCODE segmentation predictions, Jamie C. Kwasnieski, Christopher Fiore, Hemangi G. Chaudhari, and Barak A. Cohen

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Rationing lung transplants--procedural fairness in allocation and appeals, Keren Ladin and Douglas W. Hanto

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Genome-wide mapping of the distribution of CarD, RNAP σA, and RNAP β on the Mycobacterium smegmatis chromosome using chromatin immunoprecipitation sequencing, Robert Landick, Azra Krek, Michael S. Glickman, Nicholas D. Socci, and Christina L. Stallings

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Outpatient parenteral antimicrobial therapy practices among adult infectious disease physicians, Michael A. Lane, Jonas Marschall, Susan E. Beekman, Philip M. Polgreen, Ritu Banerjee, Adam L. Hersh, and Hilary M. Babcock

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Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection, Marion C. Lanteri, Michael S. Diamond, Jacqueline P. Law, Glen M. Chew, Shiquan Wu, Heather C. Inglis, Derek Wong, Michael P. Busch, Philip J. Norris, and Lishomwa C. Ndhlovu

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Effectiveness of screening hospital admissions to detect asymptomatic carriers of Clostridium difficile: A modeling evaluation, Cristina Lanzas and Erik R. Dubberke

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First report of Klebsiella pneumonia carbapenemase-producing Pseudomonas aeruginosa isolated from burn patients in Iran: Phenotypic and genotypic methods, Abdolaziz Rastegar Lari, Leila Azimi, Mohammad Rahbar, Reza Alaghehbandan, and Mahboobeh Sattarzadeh-Tabrizi

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Cortical–subcortical interactions in hypersomnia disorders: Mechanisms underlying cognitive and behavioral aspects of the sleep–wake cycle, Linda J. Larson-Prior, Yo-El Ju, and James E. Galvin