The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2009
What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang
Key role of T cell defects in age-related vulnerability to West Nile virus, James D. Brien, Jennifer L. Uhrlaub, Alec Hirsch, Clayton A. Wiley, and Janko Nikolich-Zugich
Test-retest reliability of web-based retrospective self-report of tobacco exposure and risk, Janet Brigham, Christina N. Lessov-Schlaggar, Harold S. Javitz, Ruth E. Krasnow, Mary McElroy, and Gary E. Swan
Helminth genomics: The implications for human health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, and Sara Lustigman
αII-spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury, Gretchen M. Brophy, Jose A. Pineda, Linda Papa, Stephen B. Lewis, Alex B. Valadka, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Joseph J. Tepas III, Andrea Gabrielli, Steven Robicsek, Kevin K.W Wang, Claudia S. Robertson, and Ronald L. Hayes
Dorsal root ganglion neurons react to semaphorin 3A application through a biphasic response that requires multiple myosin II isoforms, Jacquelyn A. Brown, Robert B. Wysolmerski, and Paul C. Bridgman
Factors influencing the implementation of school wellness policies in the United States, 2009, Elizabeth L. Budd, Cynthia Schwarz, Byron W. Yount, and Debra Haire-Joshu
Patellar resurfacing compared with nonresurfacing in total knee arthroplasty: A concise follow-up of a randomized trial, R. Stephen Burnett, Julienne L. Boone, Seth D. Rosenzweig, and Karen Steger-May
Antimicrobial therapy for acute colonic diverticulitis, Matthew C. Byrnes and John E. Mazuski
Robotic-assisted partial nephrectomy: Surgical technique using a 3-arm approach and sliding-clip renorrhaphy, Jose M. Cabello, Brian M. Benway, and Sam B. Bhayani
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease, Ken Cadwell, Khushbu K. Patel, Masaaki Komatsu, Herbert W. Virgin IV, and Thaddeus S. Stappenbeck
Chimeric IgH-TCR/ translocations in T lymphocytes mediated by RAG, Elsa Callen, Sam Bunting, Ching-Yu Huang, Michael J. Difilippantonio, Nancy Wong, Bernard Khor, Grace Mahowald, Michael J. Kruhlak, Thomas Ried, Barry P. Sleckman, and Andre Nussenzweig
Impact of an antimicrobial utilization program on antimicrobial use at a large teaching hospital: A randomized controlled trial, Bernard C. Camins, Mark D. King, Jane B. Wells, Heidi L. Googe, Manish Patel, Ekaterina V. Kourbatova, and Henry M. Blumberg
In vitro and murine efficacy and toxicity studies of nebulized SCC1, a methylated caffeine-silver(I) complex, for treatment of pulmonary infections, Carolyn L. Cannon, Lisa A. Hogue, Ravy K. Vajravelu, George H. Capps, Aida Ibricevic, Khadijah M. Hindi, Aysegul Kascatan-Nebioglu, Michael J. Walter, Steven L. Brody, and Wiley J. Youngs
The psychoses: Cluster 3 of the proposed meta-structure for DSM-V and ICD-11, W. T. Carpenter Jr., J. R. Bustillo, G. K. Thaker, J. van Os, R. F. Krueger, and M. J. Green
Recombinant Listeria monocytogenes expressing a cell wall-associated listeriolysin O is weakly virulent but immunogenic, Javier A. Carrero, Boris Calderon, Hector Vivanco-Cid, and Emil R. Unanue
Risky sexual behaviors and sexually transmitted diseases: a comparison study of cocaine-dependent individuals in treatment versus a community-matched sample, Patricia A. Cavazos-Rehg, Edward L. Spitznagel, Mario Schootman, Jaime R. Strickland, Stephanie E. Afful, Linda B. Cottler, and Laura Jean Bierut
Plumbing the depths of urinary tract obstruction by using murine models, Feng Chen
KirBac1.1: It's an inward rectifying potassium channel, Wayland W.L. Cheng, Decha Enkvetchakul, and Colin G. Nichols
G protein subunit dissociation and translocation regulate cellular response to receptor stimulation, Mariangela Chisari, Deepak Kumar Saini, Joon-Ho Cho, Vani Kalyanaraman, and N. Gautam
Activated by different signals, the PhoP/PhoQ two-component system differentially regulates metal uptake, Eunna Choi, Eduardo A. Groisman, and Dongwoo Shin
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex, Hyongi Chon, Alex Vassilev, Melvin L. DePamphilis, Yingming Zhao, Junmei Zhang, Peter M. Burgers, Robert J. Crouch, and Susana M. Cerritelli
Identification of deleterious mutations within three human genomes, Sung Chun and Justin C. Fay
Task control signals in pediatric Tourette syndrome show evidence of immature and anomalous functional activity, Jessica A. Church, Kristin K. Wenger, Nico U.F. Dosenbach, Francis M. Miezin, Steven E. Petersen, and Bradley L. Schlaggar
A genomic score prognostic of outcome in trauma patients, J. P. Cobb and et al.
Developmental course of autistic social impairment in males, John N. Constantino, Anna M. Abbacchi, Patricia D. Lavesser, Hannah Reed, Leah Givens, Lily Chang, Teddi Gray, Maggie Gross, Yi Zhang, and Richard D. Todd
Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment, Alana C. Conti, James W. Maas Jr., Krista L. Moulder, Xiaoping Jiang, Bhumy A. Dave, Steven Mennerick, and Louis J. Muglia
Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons, Devon C. Crawford, Krista L. Moulder, Robert W. Gereau IV, Gina M. Story, and Steven Mennerick
Power and false-positive rates for the restricted partition method (RPM) in a large candidate gene data set, Robert Culverhouse, Wu Jin, Carol H. Jin, Anthony L. Hinrichs, and Brian K. Suarez
Topics in biomedical optics: Introduction to the feature issue, Joseph P. Culver, Wolfgang Drexler, Rebekah A. Drezek, Irene Georgakoudi, Elizabeth M C Hillman, and Rebecca Richards-Kortum
Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses, L Adrienne Cupples, Joseph Beyene, Heike Bickeböller, E Warwick Daw, M Daniele Fallin, W James Gauderman, Saurabh Ghosh, Ellen L. Goode, Elizabeth R. Hauser, Anthony Hinrichs, Jack W. Kent Jr, Lisa J. Martin, Maria Martinez, Rosalind J. Neuman, Michael Province, Silke Szymczak, Marsha A. Wilcox, Andreas Ziegler, Jean W. MacCluer, and Laura Almasy
Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy, Dru S. Dace, Aslam A. Khan, Jennifer L. Stark, Jennifer Kelly, Anne H. Cross, and Rajendra S. Apte
Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., and Michael S. Diamond
Lung and heart-lung transplantation, Hiroshi Date and Stuart C. Sweet
Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, and Steven U. Walkley
Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence, Paul H. Davis, Minghe Chen, Xiaochun Zhang, C. Graham Clark, R. Reid Townsend, and Samuel L. Stanley Jr.
A framework for analyzing both linkage and association: An analysis of Genetic Analysis Workshop 16 simulated data, E Warwick Daw, Jevon Plunkett, Mary Feitosa, Xiaoyi Gao, Andrew Van Brunt, Duanduan Ma, Jacek Czajkowski, Michael A. Province, and Ingrid Borecki
Considering usual medical care in clinical trial design, Liza Dawson, Deborah A. Zarin, Ezekiel J. Emanuel, Lawrence M. Friedman, Bimal Chaudhari, and Steven N. Goodman
Should burden of disease estimates include cannabis use as a risk factor for psychosis?, Louisa Degenhardt, Wayne D. Hall, Michael Lynskey, John McGrath, Jennifer McLaren, Bianca Calabria, Harvey Whiteford, and Theo Vos
Depth sensitivity and image reconstruction analysis of dense imaging arrays for mapping brain function with diffuse optical tomography, Hamid Dehghani, Brian R. White, Benjamin W. Zeff, Andrew Tizzard, and Joseph P. Culver
Skin-derived TSLP triggers progression from epidermal- barrier defects to asthma, Shadmehr Demehri, Mitsuru Morimoto, Michael J. Holtzman, and Raphael Kopan
Mechanisms of evasion of the type i interferon antiviral response by flaviviruses, Michael S. Diamond
Virus and host determinants of West Nile virus pathogenesis, Michael S. Diamond
Umbilical artery Doppler indices in small for gestational age fetuses: Correlation with adverse outcomes and placental abnormalities, Jeffrey M. Dicke, Phyllis Huettner, Sida Yan, Anthony Odibo, and Frederick T. Kraus
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death, Abhinav Diwan, Scot J. Matkovich, Qunying Yuan, Wen Zhao, Atsuko Yatani, Joan Heller Brown, Jeffrey D. Molkentin, Evangelia G. Kranias, and Gerald W. Dorn II
Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation, Lindzy F. Dodson, Jonathan S. Boomer, Christine M. Deppong, Dulari D. Shah, Julia Sim, Traci L. Bricker, John H. Russell, and Jonathan M. Green
Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways, Maribel Donoso, Jorge Cancino, Jiyeon Lee, Peter van Kerkhof, Claudio Retamal, Guojun Bu, Alfonso Gonzalez, Alfredo Cáceres, and María-Paz Marzolo
A role for dynein in the inhibition of germ cell proliferative fate, Maia Dorsett and Tim Schedl
Multicenter study of the impact of community-onset Clostridium difficile infection on surveillance for C. difficile infection, Erik R. Dubberke, Anne M. Butler, Bala Hota, Yosef M. Khan, Julie E. Mangino, Jeanmarie Mayer, Kyle J. Popovich, Kurt B. Stevenson, Deborah S. Yokoe, L Clifford McDonald, John Jernigan, and Victoria J. Fraser
Artemisone and artemiside control acute and reactivated toxoplasmosis in a murine model, Ildiko R. Dunay, Wing Chi Chan, Richard K. Haynes, and L. David Sibley
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein, Julien P. Duxin, Benjamin Dao, Peter Martinsson, Nina Rajala, Lionel Guittat, Judith L. Campbell, Johannes N. Spelbrink, and Sheila A. Stewart
Disparities by race and ethnicity in cancer survivor stories available on the web, Katherine S. Eddens, Matthew W. Kreuter, Jennifer C. Morgan, Kate E. Beatty, Sina A. Jasim, Lori Garibay, Donghua Tao, Trent D. Buskirk, and Keri A. Jupka
Sequence mining and transcript profiling to explore cyst nematode parasitism, Axel A. Elling, Makedonka Mitreva, Xiaowu Gai, John Martin, Justin Recknor, Eric L. Davis, Richard S. Hussey, Dan Nettleton, James P. McCarter, and Thomas J. Baum
Distribution of Brugia malayi larvae and DNA in vector and non-vector mosquitoes: Implications for molecular diagnostics, Sara M. Erickson, Kerstin Fischer, Gary J. Weil, Bruce M. Christensen, and Peter U. Fischer
The 9-methyl group of retinal is essential for rapid Meta II decay and phototransduction quenching in red cones, Maureen E. Estevez, Alexander V. Kolesnikov, Petri Ala-Laurila, Rosalie K. Crouch, Victor I. Govardovskii, and M. Carter Cornwall
Functional brain networks develop from a ‘‘local to distributed’’ organization, Damian A. Fair, Alexander L. Cohen, Jonathan D. Power, Nico U. F. Dosenbach, Jessica A. Church, Fancis M. Miezin, Bradley L. Schlaggar, and Steven E. Petersen
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis, Gregory D. Fairn, Koji Ogata, Roberto J. Botelho, Philip D. Stahl, Richard A. Anderson, Pietro De Camilli, Tobias Meyer, Shoshana Wodak, and Sergio Grinstein
Reference equation for 6-minute walk in individuals with Parkinson disease, Michael J. Falvo and Gammon M. Earhart
Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration, Amy M. Fang, Aaron Y. Lee, Mukti Kulkarni, Melissa P. Osborn, and Milam A. Brantley Jr.
Multiple loci within the major histocompatibility complex confer risk of psoriasis, Bing-Jian Feng, Liang-Dan Sun, Razieh Soltani-Arabshahi, Anne M. Bowcock, Rajan P. Nair, Philip Stuart, James T. Elder, Steven J. Schrodi, Ann B. Begovich, Goncalo R. Abecasis, Xue-Jun Zhang, Kristina P. Callis-Duffin, Gerald G. Krueger, and David E. Goldgar
PfeIK1, a eukaryotic initiation factor 2α kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation, Clare Fennell, Shalon Babbitt, Ilaria Russo, Jonathan Wilkes, Lisa Ranford-Cartwright, Daniel E. Goldberg, and Christian Doerig
Human stool contains a previously unrecognized diversity of novel astroviruses, Stacy R. Finkbeiner, Lori R. Holtz, Yanfang Jiang, Priya Rajendran, Carl J. Franz, Guoyan Zhao, Gagandeep Kang, and David Wang
Detection of newly described astrovirus MLB1 in stool samples from children, Stacy R. Finkbeiner, Binh-Minh Le, Lori R. Holtz, Gregory A. Storch, and David Wang
Multiplicative auditory spatial receptive fields created by a hierarchy of population codes, Brian J. Fischer, Charles H. Anderson, and Jose Luis Pena
Discovering structural cis-regulatory elements by modeling the behaviors of mRNAs, Barrett C. Foat and Gary D. Stormo
Zero: What is it, and how do we get there?, Victoria J. Fraser
Detailed analysis of a contiguous 22-Mb region of the maize genome, Robert S. Fulton, Laura Courtney, Scott Kruchowski, Tina A. Graves, Susan M. Rock, Stephanie Adams, Lucinda A. Fulton, Catrina Fronick, William Courtney, Sandra W. Clifton, Richard K. Wilson, and et al.
Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in helicobacter pylori-infected Peruvians, Sebastian Gehmert, Billie Velapatiño, Phabiola Herrera, Jaqueline Balqui, Livia Santivañez, Jamie Cok, Gloria Vargas, Juan Combe, Douglas J. Passaro, Sijin Wen, Frank Meyer, Douglas E. Berg, and Robert H. Gilman
Early results of the Ponseti method for the treatment of clubfoot associated with myelomeningocele, David J. Gerlach, Christina A. Gurnett, Noppachart Limpaphayom, Farhang Alaee, Zhongli Zhang, Kristina Porter, Melissa Kirchhofer, Matthew D. Smyth, and Matthew B. Dobbs
The urban environment and childhood asthma (URECA) birth cohort study: Design, methods, and study population, James E. Gern, Cynthia M. Visness, Peter J. Gergen, Robert A. Wood, Gordon R. Bloomberg, George T. O'Connor, Meyer Kattan, Hugh A. Sampson, Frank R. Witter, Megan T. Sandel, Wayne G. Shreffler, Rosalind J. Wright, Samuel J. Arbes Jr, and William W. Busse
Environment-specific combinatorial cis-regulation in synthetic promoters, Jason Gertz and Barak A. Cohen
Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites, Santhosh Girirajan, Lin Chen, Tina Graves, Tomas Marques-Bonet, Mario Ventura, Catrina Fronick, Lucinda Fulton, Mariano Rocchi, Robert S. Fulton, Richard K. Wilson, Elaine R. Mardis, and Evan E. Eichler
The mitogen-activated protein kinase scaffold KSR1 Is required for recruitment of extracellular signal-regulated kinase to the immunological synapse, Emanuele Giurisato, Joseph Lin, Angus Harding, Elisa Cerutti, Marina Cella, Robert E. Lewis, Marco Colonna, and Andrey S. Shaw
Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling, Hilary P. Glazer, Robert M. Osipov, Richard T. Clements, Frank W. Sellke, and Cesario Bianchi
Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11, D. P. Goldberg, R. F. Krueger, G. Andrews, and M. J. Hobbs
Amniotic constriction band: A multidisciplinary assessment of etiology and clinical presentation, Charles A. Goldfarb, Achara Sathienkijkanchai, and Nathaniel H. Robin
Loss of A-type lamins and genomic instability, Ignacio Gonzalez-Suarez, Abena B. Redwood, and Susana Gonzalo
Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation, Elena Gracheva, Monica Dus, and Sarah C. R. Elgin
ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivo, Daniel B. Graham, Bernd H. Zinselmeyer, Francesca Mascarenhas, Ryan Delgado, Mark J. Miller, and Wojiech Swat
Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis, Timothy A. Graubert, Michelle A. Payton, Jin Shao, Richard A. Walgren, Ryan S. Monahan, John L. Frater, Mark A. Walshauser, Mike G. Martin, Yumi Kasai, and Matthew J. Walter
Reevaluating humeral length for the detection of fetal trisomy 21, Diana L. Gray, Jeffrey M. Dicke, Rachel Dickerson, Carolyn McCourt, and Anthony O. Odibo
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain, Karrie E. Grear, I-Fang Ling, James F. Simpson, Jennifer L. Furman, Christopher R. Simmons, Shawn L. Peterson, Frederick A. Schmitt, William R. Markesbery, Qiang Liu, Julia E. Crook, Steven G. Younkin, Guojun Bu, and Steven Estus
Comparison of three reference methods for testing susceptibility of Staphylococci to trimethoprim-sulfamethoxazole, R. Griffith, D. Creely, P. Revell, W. Michael Dunne, and D. Shortridge
Dyskerin, telomerase and the DNA damage response, BaiWei Gu, Monica Bessler, and Philip J. Mason
Genetic association analysis of coronary heart disease by profiling gene-environment interaction based on latent components in longitudinal endophenotypes, C Charles Gu, Wei (Will) Yang, Aldi T. Kraja, Lisa de las Fuentes, and Victor G. Davila-Roman
Contribution of autolysin and sortase A during Enterococcus faecalis DNA-dependent biofilm development, Pascale S. Guiton, Chia S. Hung, Kimberly A. Kline, Robyn Roth, Andrew L. Kau, Ericka Hayes, John Heuser, Karen W. Dodson, Michael G. Caparon, and Scott J. Hultgren
Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair, Arun Gupta, Qin Yang, Raj K. Pandita, Clayton R. Hunt, Tao Xiang, Sandeep Misri, Sicong Zeng, Rakesh Kumar, Zhihui Feng, Simon N. Powell, Audesh Bhat, Tej K. Pandita, and et al
Effects of dance on movement control in Parkinson's disease: A comparison of Argentine tango and American ballroom, Madeleine E. Hackney and Gammon M. Earhart
Surveillance of obesity-related policies in multiple environments: The Missouri Obesity, Nutrition, and Activity Policy Database, 2007-2009, Debra Haire-Joshu, Michael Elliott, Rebecca Schermbeck, Elsa Taricone, Scoie Green, and Ross C. Brownson
Identifying promoter features of co-regulated genes with similar network motifs, Oscar Harari, Coral del Val, Rocío Romero-Zaliz, Dongwoo Shin, Henry Huang, Eduardo A. Groisman, and Igor Zwir
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks, Beth A. Helmink, Andrea L. Bredemeyer, Baeck-Seung Lee, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Jeffrey J. Bednarski, Wan-Ling Lee, Tej K. Pandita, Craig H. Bassing, and Barry P. Sleckman
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli, Jeffrey P. Henderson, Jan R. Crowley, Jerome S. Pinker, Jennifer N. Walker, Pablo Tsukayama, Walter E. Stamm, Thomas M. Hooton, and Scott J. Hultgren
Detecting population stratification using related individuals, Anthony L. Hinrichs, Robert Culverhouse, Carol H. Jin, and Brian K. Suarez
Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread, Lori R. Holtz, Stacy R. Finkbeiner, Guoyan Zhao, Carl D. Kirkwood, Rosina Girones, James M. Pipas, and David Wang
Modeling the quantitative specificity of DNA-binding proteins from example binding sites, Dana S. F. Homsi, Vineet Gupta, and Gary D. Stormo
The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner, S. Sean Houshmandi, Ryan J. Emnett, Marco Giovannini, and David H. Gutmann
Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes, Keith A. Hultman, Erine H. Budi, Daniel C. Teasley, Andrew Y. Gottlieb, David M. Parichy, and Stephen L. Johnson
Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation, Yasudo Ido, Jens R. Nyengaard, Kathy Chang, Ronald G. Tilton, Charles Kilo, Banavara L. Mylari, Peter J. Oates, and Joseph R. Williamson
RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival, Miyuki Inoue-Mochita, Toshihiro Inoue, David L. Epstein, Kendall J. Blumer, and Ponugoti V. Rao
The many faces of RET dysfunction in kidney, Sanjay Jain
