The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2022

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An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma, Odai Darawshi, Barbara Muz, and et al.

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Reevaluation of the role of LIP-1 as an ERK/MPK-1 dual specificity phosphatase in the C. elegans germline, Debabrata Das, Jacob Seemann, David Greenstein, Tim Schedl, and Swathi Arur

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Identification of novel genes and proteoforms in Angiostrongylus costaricensis through a proteogenomic approach, Esdras Matheus Gomes da Silva, Karina Mastropasqua Rebello, Young-Jun Choi, Vitor Gregorio, Alexandre Rossi Paschoal, Makedonka Mitreva, James H McKerrow, Ana Gisele da Costa Neves-Ferreira, and Fabio Passetti

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JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency, Jui M. Dave, Robert Mecham, and et al

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Pleiotropic effects of simvastatin and losartan in preclinical models of post-traumatic elbow contracture, Michael A David, Alex J Reiter, Chelsey L Dunham, Ryan M Castile, James A Abraham, Leanne E Iannucci, Ishani D Shah, Necat Havlioglu, Aaron M Chamberlain, and Spencer P Lake

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Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer, Andrew A Davis, Katherine Clifton, Whitney L. Hensing, Nusayba A. Bagegni, Foluso O. Ademuyiwa, Ron Bose, Cynthia X. Ma, and et al.

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Conditional loss of IKKα in Osterix + cells has no effect on bone but leads to age-related loss of peripheral fat, Jennifer L Davis, Nitin Kumar Pokhrel, Linda Cox, Nidhi Rohatgi, Roberta Faccio, and Deborah J Veis

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WormBase in 2022-data, processes, and tools for analyzing Caenorhabditis elegans, Paul Davis, Tim Schedl, and et al

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Modifications to student quarantine policies in K-12 schools implementing multiple COVID-19 prevention strategies restores in-person education without increasing SARS-CoV-2 transmission risk, January-March 2021, Patrick Dawson, Sara Malone, Stephanie A. Fritz, Brock K. Montgomery, Mary Boyle, Brett Maricque, Albert M. Lai, Julie A. Neidich, Rachel C. Orscheln, Jason G Newland, and et al.

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Investing in late-life Brain Capital, Walter D Dawson, Eric J Lenze, and et al.

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Clinical and kidney structural characteristics of living kidney donors with nephrolithiasis and their long-term outcomes, Matthew R D'Costa, Massini A Merzkani, Aleksandar Denic, Aidan F Mullan, Joseph J Larson, Walter K Kremers, Walter D Park, Mariam P Alexander, Harini A Chakkera, Sandra J Taler, Stephen J Erickson, Mark D Stegall, Naim Issa, and Andrew D Rule

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Immune deconvolution and temporal mapping identifies stromal targets and developmental intervals for abrogating murine low-grade optic glioma formation, Amanda de Andrade Costa, Jit Chatterjee, Olivia Cobb, Elizabeth Cordell, Astoria Chao, Suzanne Schaeffer, Andrea Goldstein, Sonika Dahiya, and David H Gutmann

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Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures, Joshua T Dearborn, Hemanth R Nelvagal, Nicholas R Rensing, Keigo Takahashi, Stephanie M Hughes, Thomas M Wishart, Jonathan D Cooper, Michael Wong, and Mark S Sands

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Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI, Farah Deba, Kemburli Munoz, Eloisa Peredia, Gustav Akk, and Ayman K Hamouda

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MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques, Jeremy D DeBarry, Xuntian Jiang, Daniel S Ory, and et al.

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Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium, Gabriel A de Erausquin, Carlos Cruchaga, Igor Zwir, and et al

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Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrent IDH wild-type glioblastoma, John F de Groot, Albert H Kim, and et al.

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Pilot study: PARP1 imaging in advanced prostate cancer, Farrokh Dehdashti, Melissa A. Reimers, Kooresh I. Shoghi, Delphine L. Chen, Jingqin Luo, Buck Rogers, Russell K. Pachynski, Sreeja Sreekumar, Cody Weimholt, and Dong Zhou

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Semiautomated analysis of an optical ATP indicator in neurons, Taher Dehkharghanian, Arsalan Hashemiaghdam, and Ghazaleh Ashrafi

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Measurement matters: An individual differences examination of family socioeconomic factors, latent dimensions of children's experiences, and resting state functional brain connectivity in the ABCD sample, Meriah L DeJoseph, Max P Herzberg, Robin D Sifre, Daniel Berry, and Kathleen M Thomas

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An approach for evaluating the effects of dietary fiber polysaccharides on the human gut microbiome and plasma proteome, Omar Delannoy-Bruno, Chandani Desai, Ruteja A Barve, Jiye Cheng, Nathan Han, Stacey Marion, Andrew C Heath, Michael J Barratt, Jeffrey I Gordon, and et al

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Mitochondrial RNA modifications shape metabolic plasticity in metastasis, Sylvain Delaunay, Gloria Pascual, Bohai Feng, Kevin Klann, Mikaela Behm, Agnes Hotz-Wagenblatt, Karsten Richter, Karim Zaoui, Esther Herpel, Christian Münch, Sabine Dietmann, Jochen Hess, Salvador Aznar Benitah, and Michaela Frye

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The future of AD clinical trials with the advent of anti-amyloid therapies: An CTAD Task Force report, J Delrieu, R J Bateman, J Touchon, M Sabbagh, and J Cummings

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FMRP regulates GABAA receptor channel activity to control signal integration in hippocampal granule cells, Pan-Yue Deng, Ajeet Kumar, Valeria Cavalli, and Vitaly A Klyachko

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Neurogenetic and epigenetic aspects of cannabinoids, Catherine A Dennen, Kenneth Blum, Abdalla Bowirrat, Jag Khalsa, Panayotis K Thanos, David Baron, Rajendra D Badgaiyan, Ashim Gupta, Eric R Braverman, and Mark S Gold

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Genetic addiction risk severity assessment identifies polymorphic reward genes as antecedents to reward deficiency syndrome (RDS) hypodopaminergia's effect on addictive and non-addictive behaviors in a nuclear family, Catherine A Dennen, Kenneth Blum, Abdalla Bowirrat, Panayotis K Thanos, Igor Elman, Mauro Ceccanti, Rajendra D Badgaiyan, Thomas McLaughlin, Ashim Gupta, Anish Bajaj, David Baron, B William Downs, Debasis Bagchi, and Mark S Gold

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Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG), Ami V Desai, Karen Gauvain, Amy E Armstrong, and et al.

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A short-term multicenter analysis of radiolucent lines in a single uncemented rotating platform implant for total knee arthroplasty, Jason Desmarais, David Dalury, Thomas L. Bernasek, David A. Fisher, Ryan M. Nunley, Marie-Claire Fickenscher, and Robert S Gorab

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A guide for managing patients with stage I NSCLC: Deciding between lobectomy, segmentectomy, wedge, SBRT and ablation-part 1: A guide to decision-making, Frank C. Detterbeck, Justin D. Blasberg, Gavitt A. Woodard, Roy H. Decker, Ulas Kumbasar, Henry S. Park, Vincent J. Mase Jr, Brett C. Bade, Andrew X. Li, Whitney S. Brandt, and David C. Madoff

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A guide for managing patients with stage I NSCLC: Deciding between lobectomy, segmentectomy, wedge, SBRT and ablation-part 2: Systematic review of evidence regarding resection extent in generally healthy patients, Frank C. Detterbeck, Vincent J. Mase, Andrew X. Li, Ulas Kumbasar, Brett C. Bade, Henry S. Park, Roy H. Decker, David C. Madoff, Gavitt A. Woodard, Whitney S Brandt, and Justin D. Blasberg

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Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers, Rachel A DeWeerd, Eszter Németh, Ádám Póti, Nataliya Petryk, Chun-Long Chen, Olivier Hyrien, Dávid Szüts, and Abby M Green

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Interim outcomes of mechanical thrombectomy for deep vein thrombosis from the all-comer CLOUT registry, David J Dexter, Luis Sanchez, and et al.

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Synthesis and structure-activity relationship of thioacetamide-triazoles against Escherichia coli, Suresh Dharuman, Miranda J Wallace, Stephanie M Reeve, Jürgen B Bulitta, and Richard E Lee

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Association of male hypogonadism with risk of hospitalization for COVID-19, Sandeep Dhindsa, Cosette Champion, Ekamjit Deol, Matthew Lui, Robert Campbell, Jennifer Newman, Aparna Yeggalam, Srikanth Nadella, Vaishaliben Ahir, Ekta Shrestha, Thomas Kannampallil, and Abhinav Diwan

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HDL composition, heart failure, and its comorbidities, Ahmed Diab, Carla Valenzuela Ripoll, Zhen Guo, and Ali Javaheri

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Choline, DHA, and diarrheal disease associated with growth faltering in a case-control study, Jenna N Diaz, Sherlie Jean Louis Dulience, Noah Wolthausen, Xuntian Jiang, Emmanuel Gyimah, Francesca J Marhône Pierre, F Matthew Kuhlmann, and Lora L Iannotti

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Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites, Noah M. Dietzen, Mark J. Arcario, Lawrence J. Chen, John T. Petroff, K. Trent Moreland, Kathiresan Krishnan, Grace Brannigan, Douglas F. Covey, and Wayland W.I. Cheng

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American Cochlear Implant Alliance Task Force guidelines for clinical assessment and management of adult cochlear implantation for single-sided deafness, Margaret T. Dillon, Armine Kocharyan, Ghazal S. Daher, Matthew L. Carlson, William H. Shapiro, Hillary A. Snapp, and Jill B. Firszt

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Comparative proteomics of adult Paragonimus kellicotti excretion/secretion products released in vitro or present in the lung cyst nodule, Lucia S. Di Maggio, Kurt C. Curtis, Petra Erdmann-Gilmore, Robert S. W. Sprung, R. Reid Townsend, Gary J. Weil, and Peter U. Fischer

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RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells, Orsola Di Martino, Margaret A. Ferris, Gayla Hadwiger, Soyi Sarkar, Anh Vu, María P. Menéndez-Gutiérrez, Mercedes Ricote, and John S Welch

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An overview of treatment options for patients with relapsed/refractory multiple myeloma and renal impairment, Meletios A Dimopoulos, Joseph Mikhael, Evangelos Terpos, Xavier Leleu, Philippe Moreau, Joan Bladé, Jin Seok Kim, Keith Stockerl-Goldstein, and Paul G Richardson

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Macrophage depletion blocks congenital SARM1-dependent neuropathy, Caitlin B Dingwall, Amy Strickland, Sabrina W Yum, Aldrin Ky Yim, Jian Zhu, Peter L. Wang, Yurie Yamada, Robert E. Schmidt, Yo Sasaki, A. Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt

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Association of molecular senescence markers in late-life depression with clinical characteristics and treatment outcome, Breno S Diniz, Benoit H Mulsant, Charles F Reynolds, Daniel M Blumberger, Jordan F Karp, Meryl A Butters, Ana Paula Mendes-Silva, Erica L Vieira, George Tseng, and Eric J Lenze

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Genomic surveillance of clinical Pseudomonas aeruginosa isolates reveals an additive effect of carbapenemase production on carbapenem resistance, Luke Diorio-Toth, Sidra Irum, Robert F Potter, Meghan A Wallace, Muhammad Arslan, Tehmina Munir, Saadia Andleeb, Carey-Ann D Burnham, and Gautam Dantas

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Sleep-promoting neurons remodel their response properties to calibrate sleep drive with environmental demands, Stephane Dissel, Markus K. Klose, Bruno van Swinderen, Lijuan Cao, Melanie Ford, Erica M. Periandri, Joseph D. Jones, Zhaoyi Li, and Paul J. Shaw

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Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis, Leon Di Stefano, Jane A. O'Halloran, Adriana M. Rauseo, and et al

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Evolutionarily stable gene clusters shed light on the common grounds of pathogenicity in the Acinetobacter calcoaceticus-baumannii complex, Bardya Djahanschiri, Gisela Di Venanzio, Jesus S. Distel, Jennifer Breisch, Marius Alfred Dieckmann, Alexander Goesmann, Beate Averhoff, Stephan Göttig, Gottfried Wilharm, Mario F. Feldman, and Ingo Ebersberger

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Cardiovascular tropism and sequelae of SARS-CoV-2 infection, Oleksandr Dmytrenko and Kory J Lavine

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The metabolism of human soluble Amyloid Precursor Protein isoforms is quantifiable by a stable isotope labeling-tandem mass spectrometry method, Justyna A Dobrowolska Zakaria, Randall J Bateman, Monika Lysakowska, Ammaarah Khatri, Dinorah Jean-Gilles, Matthew E Kennedy, and Robert Vassar

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Challenges and progress in research, diagnostics, and therapeutics in Alzheimer's disease and related dementias, Nikolay V Dokholyan, Richard C Mohs, and Randall J Bateman

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Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment, Kristine Donahue, Haibo Xie, Miyang Li, Ang Gao, Min Ma, Yidan Wang, Rose Tipton, Nicole Semanik, Tina Primeau, Shunqiang Li, Lingjun Li, Weiping Tang, and Wei Xu

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A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells, Chen Dong, Shuhua Fu, Rowan M Karvas, Brian Chew, Laura A Fischer, Xiaoyun Xing, Jessica K Harrison, Pooja Popli, Ramakrishna Kommagani, Ting Wang, Bo Zhang, and Thorold W Theunissen

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A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells, Chen Dong, Shuhua Fu, Rowan M Karvas, Brian Chew, Laura A Fischer, Xiaoyun Xing, Jessica K Harrison, Pooja Popli, Ramakrishna Kommagani, Ting Wang, Bo Zhang, and Thorold W Theunissen

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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia, Qianze Dong, Nick Borcherding, and et al.

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Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia, Weilai Dong, Sheng Chih Jin, and et al.

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Mutation spectrum of congenital heart disease in a consanguineous Turkish population, Weilai Dong, Hande Kaymakcalan, Sheng Chih Jin, Nicholas S Diab, Cansaran Tanıdır, Ali Seyfi Yalim Yalcin, A Gulhan Ercan-Sencicek, Shrikant Mane, Murat Gunel, Richard P Lifton, Kaya Bilguvar, and Martina Brueckner

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Coordination of sustainable financing for evidence-based youth mental health treatments: Protocol for development and evaluation of the fiscal mapping process, Alex R Dopp, Marylou Gilbert, Jane Silovsky, Jeanne S Ringel, Susan Schmidt, Beverly Funderburk, Ashley Jorgensen, Byron J Powell, Douglas A Luke, David Mandell, Daniel Edwards, Mellicent Blythe, and Dana Hagele

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Integrating the OHIF Viewer into XNAT: Achievements, challenges and prospects for quantitative imaging studies, Simon J. Doran, Woonchan Cho, Dan Marcus, and et al

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Predicting mitochondrial dynamic behavior in genetically defined neurodegenerative diseases, Gerald W Dorn II and Xiawei Dang

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Nuclear morphometry and chromatin texture changes in hepatocellular carcinoma samples may predict outcomes of liver transplanted patients, Jordan Boeira Dos Santos, Rodrigo Tzovenos Starosta, Emily Ferreira Salles Pilar, Jefferson Daniel Kunz, Joelson Tomedi, Carlos Thadeu Schmidt Cerski, and Rúbia Denise Ruppenthal

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Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?, Joseph D Dougherty, Natasha Marrus, Susan E Maloney, Benjamin Yip, Sven Sandin, Tychele N Turner, Din Selmanovic, Kristen L Kroll, David H Gutmann, John N Constantino, and Lauren A Weiss

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Inhibiting Mycobacterium abscessus cell wall synthesis: Using a novel diazabicyclooctane β-lactamase inhibitor to augment β-lactam action, Khalid M Dousa, David C Nguyen, Sebastian G Kurz, Magdalena A Taracila, Christopher R Bethel, William Schinabeck, Barry N Kreiswirth, Sheldon T Brown, W Henry Boom, Richard S Hotchkiss, Kenneth E Remy, Frank J Jacono, Charles L Daley, Steven M Holland, Alita A Miller, and Robert A Bonomo

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A pharmacokinetic analysis of tobramycin in patients less than five years of age with cystic fibrosis: Assessment of target attainment with extended-interval dosing through simulation, Kevin J Downes, Austyn Grim, Laura Shanley, Ronald C Rubenstein, Athena F Zuppa, and Marc R Gastonguay

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Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus, Jeffrey Downey, Haley E Randolph, Erwan Pernet, Kim A Tran, Shabaana A Khader, Irah L King, Luis B Barreiro, and Maziar Divangahi

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Isolation of a potently neutralizing and protective human monoclonal antibody targeting yellow fever virus, Michael P Doyle, Joseph R Genualdi, Adam L Bailey, Nurgun Kose, Christopher Gainza, Jessica Rodriguez, Kristen M Reeder, Christopher A Nelson, Prashant N Jethva, Rachel E Sutton, Robin G Bombardi, Michael L Gross, Justin G Julander, Daved H Fremont, Michael S Diamond, and James E Crowe

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Strategies to achieve breast health equity in the St. Louis region and beyond over 15+ years, Bettina Drake, Aimee James, Heidi Miller, Akila Anandarajah, Kia L Davis, Sheryll Jackson, Graham A Colditz, and Vetta Sanders Thompson

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Depression, stigma and social isolation: The psychosocial trifecta of primary chronic cutaneous lupus erythematosus, a cross-sectional and path analysis, Cristina Drenkard, Kristina A Theis, Timothy T Daugherty, Charles G Helmick, Charmayne Dunlop-Thomas, Gaobin Bao, Laura Aspey, Tené T Lewis, and S Sam Lim

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A phase I first-in-human study of ABBV-383, a B-cell maturation antigen × CD3 bispecific T-cell redirecting antibody, in patients with relapsed/refractory multiple myeloma, Anita D'Souza, Ravi Vij, and et al.

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Hierarchical and nonhierarchical features of the mouse visual cortical network, Rinaldo D D'Souza, Quanxin Wang, Weiqing Ji, Andrew M Meier, Henry Kennedy, Kenneth Knoblauch, and Andreas Burkhalter

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Functional characterization of enhancer activity during a long terminal repeat's evolution, Alan Y Du, Xiaoyu Zhuo, Vasavi Sundaram, Nicholas O Jensen, Hemangi G Chaudhari, Nancy L Saccone, Barak A Cohen, and Ting Wang

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Impact of updated clinical practice guidelines on outpatient treatment for Clostridioides difficile infection and associated clinical outcomes, Erik R Dubberke, Justin T Puckett, Engels N Obi, Sachin Kamal-Bahl, Kaushal Desai, Bruce Stuart, and Jalpa A Doshi

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Semi-quantitative assay to measure urease activity by urinary catheter-associated uropathogens, Jesus M Duran Ramirez, Jana Gomez, Chloe L P Obernuefemann, Nathaniel C Gualberto, and Jennifer N Walker

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Risk of early versus later rebleeding from dural arteriovenous fistulas with cortical venous drainage, Andrew J Durnford, Ridhima Guniganti, Akash P Kansagra, Gregory J Zipfel, and et al

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Evolution of multiple domains of the HIV-1 envelope glycoprotein during coreceptor switch with CCR5 antagonist therapy, Yueqi Du, Ellen Wu, Xiang Gao, Jie Zhang, John C Martin, Bruce A Rosa, Makedonka Mitreva, and Lee Ratner

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Stakeholder engagement in eight comparative effectiveness trials in African Americans and Latinos with asthma, Tiffany Dy, Winifred J Hamilton, C Bradley Kramer, Andrea Apter, Jerry A Krishnan, James W Stout, Stephen J Teach, Alex Federman, John Elder, Tyra Bryant-Stephens, Rebecca J Bruhl, Shawni Jackson, and Kaharu Sumino

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Modelling neurological diseases in large animals: Criteria for model selection and clinical assessment, Samantha L Eaton, Jonathan D Cooper, and et al.

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Trial of Ultrasound guided carpal tunnel release versus Traditional Open Release (TUTOR), Kyle R. Eberlin, Christopher J. Dy, Mark D. Fischer, James L. Gluck, F. Thomas D. Kaplan, Thomas J. McDonald, Larry E. Miller, Alexander Palmer, Marc E. Walker, and James F. Watt

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Development and validation of a novel anaerobic carbapenem inactivation method (Ana-CIM) for the detection of carbapenemase production in Bacteroides fragilis, Allison R Eberly, Meghan A Wallace, Samantha Shannon, Angela K Heitman, Audrey N Schuetz, Carey-Ann D Burnham, and Sophonie Jean

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Relationship between age at menopause, obesity, and incident heart failure: The Atherosclerosis Risk in Communities Study, Imo A Ebong, Machelle D Wilson, Duke Appiah, Erin D Michos, Susan B Racette, Amparo Villablanca, Khadijah Breathett, Pamela L Lutsey, Melissa Wellons, Karol E Watson, Patricia Chang, and Alain G Bertoni

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MYC sensitises cells to apoptosis by driving energetic demand, Joy Edwards-Hicks, Kevin Cho, Gary J Patti, and et al

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Control of aging by the renin-angiotensin system: A review of C. elegans, Drosophila, and mammals, Brian M Egan, Andrea Scharf, Franziska Pohl, and Kerry Kornfeld

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Characteristics of antifungal utilization for hospitalized children in the United States, Lourdes Eguiguren, Brian R Lee, Jason G Newland, Matthew P Kronman, Adam L Hersh, Jeffrey S Gerber, Grace M Lee, and Hayden T Schwenk

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Neurotoxicity: A rare side effect of programmed cell death 1 (PD-1) inhibitors, Syed Ehsanullah, Syed Hasan, Faran S Polani, Syeda Zarmeena Rashid, and Syed Ijlal Ahmed

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Immunotherapy-induced auto-splenectomy in a patient of malignant melanoma, Syed Ehsanullah, Azharuddin Muhammad, Syed Hasan, and John M. Richart

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A rare case of synovial sarcoma of the prostate causing urinary retention, Syed Ehsanullah, Syeda Zarmeena Rashid, Adeel Haq, and Saiyed Abdullah A. Ehsanullah

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Plasma neurofilament light chain levels are elevated in children and young adults with Wolfram syndrome, Sarah A Eisenstein, Raveena S Boodram, Courtney L Sutphen, Heather M Lugar, Brian A Gordon, Bess A Marshall, Fumihiko Urano, Anne M Fagan, and Tamara Hershey

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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease, Jaclyn M Eissman, Carlos Cruchaga, and et al.

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Persistence of onchocerciasis in villages in Enugu and Ogun states in Nigeria following many rounds of mass distribution of ivermectin, Uwem F Ekpo, Obiora A Eneanya, Edith N Nwankwo, Islamiat Y Soneye, Gary J Weil, Peter U Fischer, and Obioma C Nwaorgu

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Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease, Mohamed Elagawany, Ayman Abo Elmaaty, Ahmed Mostafa, Noura M Abo Shama, Eman Y Santali, Bahaa Elgendy, and Ahmed A Al-Karmalawy

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Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways, Donald L Elbert, Bruce W Patterson, Brendan P Lucey, Tammie L S Benzinger, and Randall J Bateman

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SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice, Salima El Chehadeh, Dorothy K Grange, and et al

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Spotlight on nociceptin/orphanin FQ receptor in the treatment of pain, Amal El Daibani and Tao Che

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Cutting-edge imaging of cardiac metastases from neuroendocrine tumors: Lesson from a case series, Soraya El Ghannudi, Eric Ouvrard, Nidaa Mikail, Benjamin Leroy Freschini, Thomas H Schindler, and Alessio Imperiale

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Computationally driven discovery of SARS-CoV-2 M pro inhibitors: From design to experimental validation, Léa El Khoury, Jay W Ponder, and et al

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Shiny GATOM: Omics-based identification of regulated metabolic modules in atom transition networks, Mariia Emelianova, Anastasiia Gainullina, Nikolay Poperechnyi, Alexander Loboda, Maxim Artyomov, and Alexey Sergushichev

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Community-based trial assessing the impact of annual versus semiannual mass drug administration with ivermectin plus albendazole and praziquantel on helminth infections in northwestern Liberia, Obiora A Eneanya, Lincoln Gankpala, Charles W Goss, Aaron T Momolu, Enoch S Nyan, Emmanuel B Gray, Kerstin Fischer, Kurt Curtis, Fatorma K Bolay, Gary J Weil, and Peter U Fischer

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Altered Peroxisome Proliferator-Activated Receptor alpha signaling in variably diseased peripheral arterial segments, Connor Engel, Rodrigo Meade, Nikolai Harroun, Amanda Penrose, Mehreen Shafqat, Xiaohua Jin, Gayan DeSilva, Clay Semenkovich, and Mohamed Zayed

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NeoRS: A neonatal resting state fMRI data preprocessing pipeline, Vicente Enguix, Jeanette Kenley, David Luck, Julien Cohen-Adad, and Gregory Anton Lodygensky

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Accuracy of chest computed tomography in distinguishing cystic pleuropulmonary blastoma from benign congenital lung malformations in children, Abigail J Engwall-Gill, Jacqueline M Saito, Rebecca L Hulett Bowling, and et al.

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Association of the receptor for activated C-kinase 1 with ribosomes in Plasmodium falciparum, Jessey Erath and Sergej Djuranovic