The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2021

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Green nanotechnology of MGF‑AuNPs for immunomodulatory intervention in prostate cancer therapy, Menka Khoobchandani, Aslam Khan, Kavita K. Katti, Velaphi C. Thipe, Amal Y. Al-Yasiri, Darsha K. D. MohanDoss, Michael B. Nicholl, Ademar B. Lugão, Chetan P. Hans, and Kattesh V. Katti

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Laminin β2 variants associated with isolated nephropathy that impact matrix regulation, Yamato Kikkawa, Helen Liapis, Jeffrey H. Miner, and et al.

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The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ, Denis A. Kiktev, Margaret Dominska, Tony Zhang, Joseph Dahl, Elena I. Stepchenkova, Piotr Mieczkowski, Peter M. Burgers, Scott Lujan, Adam Burkholder, Thomas A. Kunkel, and Thomas D. Petes

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The Dystonia Coalition: A multicenter network for clinical and translational studies, Gamze Kilic-Berkmen, Laura J Wright, Joel S Perlmutter, Cynthia Comella, Mark Hallett, Jan Teller, Sarah Pirio Richardson, David A Peterson, Carlos Cruchaga, Codrin Lungu, and H A Jinnah

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Lysis of arterial thrombi by perfusion of N,N'-Diacetyl-L-cystine (DiNAC), Dongjune Kim, Susan M. Shea, and David N. Ku

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The PROVe study: US real-world experience with chlormethine/mechlorethamine gel in combination with other therapies for patients with mycosis fungoides cutaneous T-cell lymphoma, Ellen J Kim, Joan Guitart, Christiane Querfeld, Michael Girardi, Amy Musiek, Oleg E Akilov, James T Angello, William L Bailey, and Larisa J Geskin

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Surgical strategy for the management of cervical deformity is based on type of cervical deformity, Han Jo Kim, Munish Gupta, and et al

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CD7-deleted hematopoietic stem cells can restore immunity after CAR T cell therapy, Miriam Y. Kim, Matthew L. Cooper, Miriam T. Jacobs, Julie K. Ritchey, Julia Hollaway, Todd A. Fehniger, and John F. DiPersio

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CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells, Myung-Chul Kim, Nicholas Borcherding, Kawther K. Ahmed, Andrew P. Voigt, Gaurav Pandey, and et al

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Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice, Sanghyun P Kim, Sridhar N Srivatsan, Monique Chavez, Cara L Shirai, Brian S White, Tanzir Ahmed, Michael O Alberti, Jin Shao, Ryan Nunley, Lynn S White, Jeff Bednarski, John R Pehrson, and Matthew J Walter

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Ngn3-positive cells arise from pancreatic duct cells, Chiemi Kimura-Nakajima, Kousuke Sakaguchi, Yoshiko Hatano, Masahito Matsumoto, Yasushi Okazaki, Keisuke Tanaka, Takumi Yamane, Yuichi Oishi, Kenji Kamimoto, and Ken Iwatsuki

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Self-reported positive impact of mentored clinical research training is associated with academic success in hematology, Allison A. King, Sara K. Vesely, Grace Dadzie, Cecelia Calhoun, Adam Cuker, Wendy Stock, Alison Walker, Josel Fritz, and Lilian Sung

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Predicting self-intercepted medication ordering errors using machine learning, Christopher Ryan King, Joanna Abraham, Bradley A. Fritz, Zhicheng Cui, William Galanter, Yixin Chen, and Thomas Kannampallil

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Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques, Hannah A. D. King, Rita E. Chen, James B. Case, Michael S. Diamond, and et al

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Naturalistic language input is associated with resting-state functional connectivity in infancy, Lucy S. King, M. Catalina Camacho, David F. Montez, Kathryn L. Humphreys, and Ian H. Gotlib

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Predicting alcohol use disorder remission: A longitudinal multimodal multi-featured machine learning approach, Sivan Kinreich, Vivia V. McCutcheon, Jessica L. Bourdon, Andrey P. Anokhin, Kathleen K. Bucholz, Meredith W. Francis, and et al.

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Global, cell non-autonomous gene regulation drives individual lifespan among isogenic C. elegans, Holly E. Kinser, Matthew C. Mosley, Isaac B. Plutzer, and Zachary Pincus

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Novel autosegmentation spatial similarity metrics capture the time required to correct segmentations better than traditional metrics in a thoracic cavity segmentation workflow, Kendall J Kiser, Arko Barman, Sonja Stieb, Clifton D Fuller, and Luca Giancardo

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The effect of convalescent plasma therapy on mortality among patients with COVID-19: Systematic review and meta-analysis, Stephen A Klassen, Brenda J Grossman, Jeffrey P Henderson, and et al

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Convalescent plasma therapy for COVID-19: A graphical mosaic of the worldwide evidence, Stephen A Klassen, Brenda J Grossman, Jeffrey P Henderson, and et al.

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Encephalitic arboviruses of Africa: Emergence, clinical presentation and neuropathogenesis, Robyn S Klein

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Protein phosphatase 4 controls circadian clock dynamics by modulating CLOCK/BMAL1 activity, Sabrina Klemz, Thomas Wallach, Sandra Korge, Mechthild Rosing, Roman Klemz, Bert Maier, Nicholas C Fiorenza, Irem Kaymak, Anna K Fritzsche, Erik D Herzog, Ralf Stanewsky, and Achim Kramer

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Increasing metadata coverage of SRA BioSample entries using deep learning-based named entity recognition, Adam Klie, Brian Y Tsui, Shamim Mollah, Dylan Skola, Michelle Dow, Chun-Nan Hsu, and Hannah Carter

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CT findings and patterns of e-cigarette or vaping product use-associated lung injury: A multicenter cohort of 160 cases, Seth J Kligerman, Constantine A Raptis, Kaitlin M Marquis, and et al.

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Clinical prediction rule for SARS-CoV-2 infection from 116 U.S. emergency departments 2-22-2021, Jeffrey A. Kline, Stacey House, and et al.

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Riociguat: Clinical research and evolving role in therapy, James R Klinger, Murali M Chakinala, David Langleben, Stephan Rosenkranz, and Olivier Sitbon

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Sleep drive reconfigures wake-promoting clock circuitry to regulate adaptive behavior, Markus K. Klose and Paul J. Shaw

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Idiopathic non-cirrhotic portal hypertension and porto-sinusoidal vascular disease: Review of current data, Michel Kmeid, Xiuli Liu, Samuel Ballentine, and Hwajeong Lee

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Opening of a cryptic pocket in β-lactamase increases penicillinase activity, Catherine R Knoverek, Upasana L Mallimadugula, Sukrit Singh, Enrico Rennella, Thomas E Frederick, Tairan Yuwen, Shreya Raavicharla, Lewis E Kay, and Gregory R Bowman

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Commonalities across computational workflows for uncovering explanatory variants in undiagnosed cases, Shilpa Nadimpalli Kobren, Dustin Baldridge, Daniel J Wegner, Alexander J Paul, and et al.

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Lack of association between acute stroke, post-stroke dementia, race, and β-amyloid status, Lauren N Koenig, Lena M McCue, Elizabeth Grant, Parinaz Massoumzadeh, Catherine M Roe, Chengjie Xiong, Krista L Moulder, Liang Wang, Allyson R Zazulia, Peggy Kelly, Aylin Dincer, Aiad Zaza, Joshua S Shimony, Tammie L S Benzinger, and John C Morris

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Brain/MINDS beyond human brain MRI project: A protocol for multi-level harmonization across brain disorders throughout the lifespan, Shinsuke Koike, Matthew F Glasser, David C Van Essen, and et al

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Live imaging reveals the cellular events downstream of SARM1 activation, Kwang Woo Ko, Laura Devault, Yo Sasaki, Jeffrey Milbrandt, and Aaron DiAntonio

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Function of mammalian M-cones depends on the level of CRALBP in Müller cells, Alexander V. Kolesnikov, Philip D. Kiser, Krzysztof Palczewski, and Vladimir J. Kefalov

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Timing of antibiotic therapy in the ICU, Marin H Kollef, Andrew F Shorr, Matteo Bassetti, Jean-Francois Timsit, Scott T Micek, Andrew P Michelson, and Jose Garnacho-Montero

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Test-retest reliability of neural correlates of response inhibition and error monitoring: An fMRI study of a stop-signal task, Ozlem Korucuoglu, Michael P Harms, Serguei V Astafiev, Semyon Golosheykin, James T Kennedy, Deanna M Barch, and Andrey P Anokhin

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RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease, Robyn Laura Kosinsky, Maria Zerche, Rodney D Newberry, and et al

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A role for IL-33-activated ILC2s in eosinophilic vasculitis, Maya E Kotas, Jérémie Dion, Steven Van Dyken, Roberto R Ricardo-Gonzalez, Claire J Danel, Camille Taillé, Luc Mouthon, Richard M Locksley, and Benjamin Terrier

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Computerized tumor multinucleation index (MuNI) is prognostic in p16+ oropharyngeal carcinoma, Can F Koyuncu, Wade L Thorstad, R D Chernock, Jingqin Luo, and et al

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Dengue and the lectin pathway of the complement system, Romchat Kraivong, Nuntaya Punyadee, M Kathryn Liszewski, John P Atkinson, and Panisadee Avirutnan

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Microbiota signals suppress B lymphopoiesis with aging in mice, Joseph R Krambs, Darlene A Monlish, Feng Gao, Laura G Schuettpelz, and Daniel C Link

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Influential periods in longitudinal clinical cardiovascular health scores, Amy E Krefman, Vito M R Muggeo, and et al.

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How do social needs cluster among low-income individuals?, Matthew W. Kreuter, Rachel Garg, Linda Li, Laura McNulty, Tess Thompson, Amy McQueen, and Alina A. Luke

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Racial residential segregation and colorectal cancer mortality in the Mississippi Delta Region, Aaron J Kruse-Diehr, Justin T McDaniel, Marquita W Lewis-Thames, Aimee S James, and Musa Yahaya

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Report dose-to-medium in clinical trials where available; A consensus from the Global Harmonisation Group to maximize consistency, Stephen F Kry, Jeff Michalski, and et al.

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Contribution of noncanonical antigens to virulence and adaptive immunity in human infection with enterotoxigenic E. coli, F.M. Kuhlmann, R.O. Laine, S. Afrin, R. Nakajima, M. Akhtar, T. Vickers, K. Parker, N.N. Nizam, V. Grigura, C.W. Goss, P. L. Felgner, D. A. Rasko, F. Qadri, and J. M. Fleckenstein

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Machine learning for modeling the progression of Alzheimer disease dementia using clinical data: A systematic literature review, Sayantan Kumar, Inez Oh, Suzanne Schindler, Albert M Lai, Philip R O Payne, and Aditi Gupta

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Isolation and characterization of a novel bacteriophage WO from Allonemobius socius crickets in Missouri, Jonah Kupritz, John Martin, Kerstin Fischer, Kurt C. Curtis, Joseph R. Fauver, Yuefang Huang, Young-Jun Choi, Wandy L. Beatty, Makedonka Mitreva, and Peter U. Fischer

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Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment, Chitaru Kurihara, Wenjun Li, Daniel Kreisel, and et al

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Acute appendicitis associated with Kawasaki disease: Case report and review of the literature, Kaku Kuroda and Morgan Stottlemyre

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NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes, Candice Kutchukian, Oscar Vivas, Maria Casas, Julia G Jones, Scott A Tiscione, Sergi Simó, Daniel S Ory, Rose E Dixon, and Eamonn J Dickson

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Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway, Hyae Yon Kweon, Se-Jin Jeong, and et al

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Genomic risk prediction for breast cancer in older women, Paul Lacaze, Yin Cao, and et al

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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability, Vasiliki Lagou, Ping An, Michael A. Province, and et al.

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Weight and body mass index change after switching to integrase inhibitors or tenofovir alafenamide among women living with HIV, Cecile D. Lahiri, Jane O'Halloran, and et al

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Machine learning analytics of resting-state functional connectivity predicts survival outcomes of glioblastoma multiforme patients, Bidhan Lamichhane, Andy G S Daniel, John J Lee, Daniel S Marcus, Joshua S Shimony, and Eric C Leuthardt

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Multi-modal biomarkers of low back pain: A machine learning approach, Bidhan Lamichhane, Dinal Jayasekera, Rachel Jakes, Matthew F Glasser, Justin Zhang, Chunhui Yang, Derayvia Grimes, Tyler L Frank, Wilson Z Ray, Eric C Leuthardt, and Ammar H Hawasli

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Functional disruptions of the brain in low back pain: A potential imaging biomarker of functional disability, Bidhan Lamichhane, Dinal Jayasekera, Rachel Jakes, Wilson Z Ray, Eric C Leuthardt, and Ammar H Hawasli

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Are Fc gamma receptor polymorphisms important in HIV-1 infection outcomes and latent reservoir size?, Helena Lamptey, Evelyn Y Bonney, Bright Adu, and George B Kyei

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Calcium carbonate nanoparticles stimulate cancer cell reprogramming to suppress tumor growth and invasion in an organ‑on‑a‑chip system, Sandra F. Lam, Kevin W. Bishop, Rachel Mintz, Lei Fang, and Samuel Achilefu

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Friends and foes: Extracellular vesicles in aging and rejuvenation, Brian V Lananna and Shin-Ichiro Imai

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Estimating the effects of race and social vulnerability on hospital admission and mortality from COVID-19, Joshua M Landman, Karen Steger-May, Karen E Joynt Maddox, Gmerice Hammond, Aditi Gupta, Adriana M Rauseo, Min Zhao, and Randi E Foraker

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Microbiota restoration reduces antibiotic-resistant bacteria gut colonization in patients with recurrent Clostridioides difficile infection from the open-label PUNCH CD study, Amy Langdon, Drew J Schwartz, Christopher Bulow, Xiaoqing Sun, Tiffany Hink, Kimberly A Reske, Courtney Jones, Carey-Ann D Burnham, Erik R Dubberke, Gautam Dantas, and CDC Prevention Epicenter Program

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A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure, Raymond J. Langley, Patrick Luckett, and et al.

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Trajectory of long-term outcome in severe pediatric diffuse axonal injury: An exploratory study, Shih-Shan Lang, Todd Kilbaugh, Stuart Friess, Susan Sotardi, Chong Tae Kim, Vanessa Mazandi, Bingqing Zhang, Phillip B Storm, Gregory G Heuer, Alexander Tucker, Steve B Ampah, Heather Griffis, Ramesh Raghupathi, and Jimmy W Huh

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Adolescent animal product intake in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study, Tuo Lan, Yikyung Park, Graham A Colditz, Jingxia Liu, Rashmi Sinha, Molin Wang, Kana Wu, Edward Giovannucci, and Siobhan Sutcliffe

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Pre-clinical common data elements for traumatic brain injury research: Progress and use cases, Michelle C. LaPlaca, Stuart H. Friess, and et al.

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Redox-responsive hyaluronic acid-based nanogels for the topical delivery of the visual chromophore to retinal photoreceptors, Amine M. Laradji, Alexander V. Kolesnikov, Bedia B. Karakoçak, Vladimir J. Kefalov, and Nathan Ravi

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Analysis of post-transplant lymphoproliferative disorder (PTLD) outcomes with Epstein-Barr virus (EBV) assessments-a single tertiary referral center experience and review of literature, Eric Lau, Lawrence Liu, and et al

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Adrenal vein sampling for ACTH-producing pheochromocytomas, Nicholas Leader, Alexander Ushinsky, and Christopher D Malone

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A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection, Tania Lebratti, Ying Shiang Lim, Adjoa Cofie, Prabhakar Andhey, Xiaoping Jiang, Jason Scott, Maria Rita Fabbrizi, Ayşe Naz Ozantürk, Christine Pham, Regina Clemens, Maxim Artyomov, Mary Dinauer, and Haina Shin

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Dynamics of oddball sound processing: Trial-by-trial modeling of ECoG signals, Françoise Lecaignard, Raphaëlle Bertrand, Peter Brunner, Anne Caclin, Gerwin Schalk, and Jérémie Mattout

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Predicting mortality risk for preterm infants using random forest, Jennifer Lee, Jinjin Cai, Fuhai Li, and Zachary A. Vesoulis

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Cardiac stereotactic ablative radiotherapy for control of refractory ventricular tachycardia: Initial UK multicentre experience, Justin Lee, Clifford Robinson, Phillip Cuculich, Geoffrey Hugo, and et al

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Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota, Sanghyun Lee, Gowri Kalugotla, Harshad Ingle, Rachel Rodgers, Yating Wang, Yuhao Li, Nicolette R Borella, Hongju Deng, Lindsay Droit, Ryan Hill, Stefan T Peterson, Chandni Desai, Dylan Lawrence, Megan T Baldridge, and et al

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Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis, Whasil Lee, Robert J. Nims, Alireza Savadipour, Qiaojuan Zhang, Holly A. Leddy, Fang Liu, Amy L. McNulty, Yong Chen, Farshid Guilak, and Wolfgang B. Liedtke

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Fabrication and evaluation of bilateral Helmholtz radiofrequency coil for thermo-stable breast image with reduced artifacts, Young Han Lee, Kyu-Ho Song, Jaemoon Yang, Won Jun Kang, Keum Sil Lee, Min Jung Kim, Eun-Kyung Kim, Dan Heo, Bo-Young Choe, and Jin-Suck Suh

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Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids, Yujin Lee, Andrew HyoungJin Kim, Eunwoo Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Jae-Yong Chung, and Joo-Youn Cho

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Phase II study of durvalumab plus tremelimumab as therapy for patients with previously treated anti-PD-1/PD-L1 resistant stage IV squamous cell lung cancer (Lung-MAP substudy S1400F, NCT03373760), Natasha B Leighl, Jeffrey D Bradley, and et al

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Rectal cancer treatment management: Deep-learning neural network based on photoacoustic microscopy image outperforms histogram-feature-based classification, Xiandong Leng, Eghbal Amidi, Sitai Kou, Hassam Cheema, Ebunoluwa Otegbeye, William Chapman Jr, Matthew Mutch, and Quing Zhu

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Evaluation of patient-reported delays and affordability-related barriers to care in head and neck cancer, Nicholas R Lenze, Jeannette T Bensen, Laura Farnan, Siddharth Sheth, Jose P Zevallos, Wendell G Yarbrough, and Adam M Zanation

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Teaching for implementation: A framework for building implementation research and practice capacity within the translational science workforce, Aaron L Leppin, Ana A Baumann, Maria E Fernandez, Brittany N Rudd, Kathleen R Stevens, David O Warner, Bethany M Kwan, and Rachel C Shelton

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A case of hepatic cyst-induced internal jugular venous thrombosis, Tuyen V Le, Thai Truong, Tam N M Ngo, Quoc Bui, Cassady Palmer, Vien T Truong, and Duc H Nguyen

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Exploring intentional medication non-adherence in patients with systemic lupus erythematosus: The role of physician-patient interactions, Jerik Leung, Elizabeth A Baker, and Alfred H J Kim

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Development of a digital toolkit to improve quality of life of patients with systemic lupus erythematosus, Jerik Leung, Laura Kloos, Alfred H Kim, and Elizabeth A Baker

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Defining surgical terminology and risk for brain computer interface technologies, Eric C Leuthardt, Daniel W Moran, and Tim R Mullen

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Centering inclusivity in the design of online conferences-An OHBM-Open Science perspective, Elizabeth Levitis, Janine D. Bijsterbosch, and et al

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First clinical experience of correcting phantom-based image distortion related to gantry position on a 0.35T MR-Linac, Benjamin C Lewis, Jaeik Shin, Benjamin Quinn, Enzo Barberi, Domenic Sievert, Jin Sung Kim, and Taeho Kim

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Evaluation of diffusion-weighted MRI and geometric distortion on a 0.35T MR-LINAC at multiple gantry angles, Benjamin Lewis, Anamaria Guta, Stacie Mackey, H Michael Gach, Sasa Mutic, Olga Green, and Taeho Kim

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Epigenetic regulation during human cortical development: Seq-ing answers from the brain to the organoid, Emily M A Lewis, Komal Kaushik, Luke A Sandoval, Irene Antony, Sabine Dietmann, and Kristen L Kroll

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Predictors of annual prostate-specific antigen (PSA) screening among black men: Results from an urban community-based prostate cancer screening program, Marquita W. Lewis-Thames, Saira Khan, Veronica Hicks, and Bettina F. Drake

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Developmental variation in testosterone: Cortisol ratio alters cortical- and amygdala-based cognitive processes, Jimin Lew, Sherri Lee Jones, Christina Caccese, Isobel Orfi, Charlotte Little, Kelly N Botteron, James T McCracken, and Tuong-Vi Nguyen

Effect of a novel smartphone application on breastfeeding rates among low-income, first-time mothers intending to exclusively breastfeed: Secondary analysis of a randomized controlled trial, Adam K. Lewkowitz, Julia D. López, Erika F. Werner, Megan L. Ranney, George A. Macones, Dwight J. Rouse, David A. Savitz, and Alison G. Cahill

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Emerging nanotechnology for treatment of Alzheimer's and Parkinson's disease, Amanda Li, Joel Tyson, Shivni Patel, Meer Patel, Sruthi Katakam, Xiaobo Mao, and Weiwei He

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Tofacitinib, an oral Janus kinase inhibitor: Analysis of malignancy (excluding nonmelanoma skin cancer) events across the ulcerative colitis clinical program, Gary R Lichtenstein, Gerhard Rogler, Matthew A Ciorba, Chinyu Su, Gary Chan, Ronald D Pedersen, Nervin Lawendy, Daniel Quirk, Chudy I Nduaka, Andrew J Thorpe, and Julian Panés

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Endoplasmic reticulum-associated biomarkers for molecular phenotyping of rare kidney disease, Chuang Li and Ying Maggie Chen

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p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response, Chuang Li, Yongsheng Huang, Qianqian Fan, Hongyang Quan, Yeqing Dong, Meng Nie, Jiaqi Wang, Fucun Xie, Jiang Ji, Lan Zhou, Zhi Zheng, and Lin Wang

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Suspected metal allergy and femoral loosening after total knee arthroplasty: A diagnostic dilemma, Elizabeth G Lieberman, Robert L Barrack, and Thomas P Schmalzried

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Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide, Sook-Lei Liew, Catherine E Lang, Anup K Bhattacharya, and et al.

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Physical activity, weight, and outcomes in patients receiving chemotherapy for metastatic breast cancer (C40502/Alliance), Jennifer A. Ligibel, Luke Huebner, Hope S. Rugo, Harold J. Burstein, Debra L. Toppmeyer, Carey K. Anders, Cynthia Ma, William T. Barry, Vera Suman, Lisa A. Carey, Ann H. Partridge, Clifford A. Hudis, and Eric P. Winer