The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2020

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Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction, Xunshan Ding, Rugmani Iyer, Christopher Novotny, Daniel Metzger, Heather H. Zhou, Gordon I. Smith, Mihoko Yoshino, Jun Yoshino, Samuel Klein, Gayathri Swaminath, Saswata Talukdar, and Yingjiang Zhou

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Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores, Hiroko H Dodge, John C Morris, and et al

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TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations, Paarth B Dodhiawala, Namrata Khurana, Daoxiang Zhang, Yi Cheng, Lin Li, Qing Wei, Kuljeet Seehra, Hongmei Jiang, Patrick M Grierson, Andrea Wang-Gillam, and Kian-Huat Lim

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Derivation of trophoblast stem cells from naïve human pluripotent stem cells, Chen Dong, Mariana Beltcheva, Paul Gontarz, Bo Zhang, Pooja Popli, Laura A. Fischer, Shafqat A Khan, Kyoung-Mi Park, Eun-Ja Yoon, Xiaoyun Xing, Ramakrishna Kommagani, Ting Wang, Lilianna Solnica-Krezel, and Thorold W. Theunissen

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Exome sequencing implicates impaired GABA signaling and neuronal ion transport in trigeminal neuralgia, Weilai Dong, Sheng Chih Jin, and et al

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FlyNet 2.0: Drosophila heart 3D (2D + time) segmentation in optical coherence microscopy images using a convolutional long short-term memory neural network, Zhao Dong, Jing Men, Zhiwen Yang, Jason Jerwick, Airong Li, Rudolph E Tanzi, and Chao Zhou

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Early socioemotional competence, psychopathology, and latent class profiles of reparative prosocial behaviors from preschool through early adolescence, Meghan Rose Donohue, Rebecca Tillman, and Joan Luby

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Therapies for tuberculosis and AIDS: Myeloid-derived suppressor cells in focus, Anca Dorhoi, Shabaana A Khader, and et al

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Serum urate lowering with allopurinol and kidney function in type 1 diabetes, Alessandro Doria, Janet B. McGill, and et al.

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Mitofusin 2 dysfunction and disease in mice and men, Gerald W Dorn II

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Proteogenomic characterization of endometrial carcinoma, Yongchao Dou, Daniel Cui Zhou, Alla Karpova, Yige Wu, Song Cao, Matthew A Wyczalkowski, Qingsong Gao, Sunantha Sethuraman, David Mutch, Katherine Fuh, Li Ding, and et al

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Evidence-based guidelines for managing patients with primary ER+ HER2− breast cancer deferred from surgery due to the COVID-19 pandemic, Mitch Dowsett, Cynthia X. Ma, and et al.

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Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases β-diversity in the gut microbiome of human immunodeficiency virus-exposed, uninfected infants, Alaric W D'Souza, Eshia Moodley-Govender, Bertram Berla, Tejas Kelkar, Bin Wang, Xiaoqing Sun, Brodie Daniels, Anna Coutsoudis, Indi Trehan, and Gautam Dantas

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Efficacy of bezlotoxumab in participants receiving metronidazole, vancomycin, or fidaxomicin for treatment of Clostridioides (Clostridium) difficile infection, Erik R. Dubberke, Dale N. Gerding, Ciarán P. Kelly, Kevin W. Garey, Galia Rahav, Audrey Mosley, Robert Tipping, and Mary Beth Dorr

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Development of a single-stranded DNA-binding protein fluorescent fusion toolbox, Katarzyna Dubiel, Camille Henry, Lisanne M. Spenkelink, Alexander G. Kozlov, Elizabeth A. Wood, Slobodan Jergic, Nicholas E. Dixon, Antoine M. van Oijen, Michael M. Cox, Timothy M. Lohman, Steven J. Sandler, and James L. Keck

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Assessing clinical research coordinator knowledge of good clinical practice: An evaluation of the state of the art and a test validation study, James M DuBois, Jessica T Mozersky, Alison L Antes, Kari Baldwin, and Michelle Jenkerson

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Safety and efficacy of co-administered diethylcarbamazine, albendazole and ivermectin during mass drug administration for lymphatic filariasis in Haiti: Results from a two-armed, open-label, cluster-randomized, community study, Christine Dubray, Anita Sircar, Madsen Beau de Rochars, Joshua Bogus, Abdel N. Direny, Jean Romuald Ernest, Carl Fayette, Charles W. Goss, Marisa Hast, Katiuscia O'Brian, Guy Emmanuel Pavilus, Daniel Frantz Sabin, Ryan Wiegand, Gary J. Weil, and Jean Frantz Lemoine

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A multi-mRNA host-response molecular blood test for the diagnosis and prognosis of acute infections and sepsis: Proceedings from a clinical advisory panel, James Ducharme, Wesley H Self, Tiffany M Osborn, Nathan A Ledeboer, Jonathan Romanowsky, Timothy E Sweeney, Oliver Liesenfeld, and Richard E Rothman

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The relation between personality and biomarkers in sensitivity and conversion to Alzheimer-type dementia, Janet M Duchek, Andrew J Aschenbrenner, Anne M Fagan, Tammie L S Benzinger, John C Morris, and David A Balota

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The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization, Kang Du, Chad Tomlinson, and et al

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Technical note: Comparison of the internal target volume (ITV) contours and dose calculations on 4DCT, average CBCT, and 4DCBCT imaging for lung stereotactic body radiation therapy (SBRT), Michael Dumas, Eric Laugeman, Parag Sevak, Karen C Snyder, Weihua Mao, Indrin J Chetty, Munther Ajlouni, and Ning Wen

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Genetic variants and functional pathways associated with resilience to Alzheimer's disease, Logan Dumitrescu, Carlos Cruchaga, and et al

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Combined abdominal heterotopic heart and aorta transplant model in mice, Hao Dun, Li Ye, Yuehui Zhu, and Brian W Wong

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Formation of lung inducible bronchus associated lymphoid tissue is regulated by Mycobacterium tuberculosis expressed determinants, Micah D Dunlap, Oliver A Prince, Javier Rangel-Moreno, Kimberly A Thomas, Julia M Scordo, Jordi B Torrelles, Jeffery Cox, Adrie J C Steyn, Joaquín Zúñiga, Deepak Kaushal, and Shabaana A Khader

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A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry, Zhaohui Du, Graham A. Colditz, Mark A. Fiala, Ravi Vij, and et al.

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Direct cost of surgically treated adult traumatic brachial plexus injuries, Christopher J Dy, Nithya Lingampalli, Kate Peacock, Margaret A Olsen, Wilson Z Ray, and David M Brogan

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Chemical effects of diceCT staining protocols on fluid-preserved avian specimens, Catherine M. Early, Ashley C. Morhardt, Timothy P. Cleland, Christopher M. Milensky, Gwénaëlle M. Kavich, and Helen F. James

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Potent, specific MEPicides for treatment of zoonotic staphylococci, Rachel L. Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T. Shah, Justin J. Miller, Andrew J. Jezewski, Marwa O. Mikati, Xu Wang, Robert C. Brothers, Kenneth M. Heidel, Damon M. Osbourn, Carey-Ann D. Burnham, Sophie Alvarez, Stephanie A. Fritz, Cynthia S. Dowd, Joseph M. Jez, and Audrey R. Odom John

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Foot salvage with selective arterialization of pedal venosomes, Maleeh Effendi, Austin Y. Ha, and John M. Felder III

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Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions, Martin T Egeland, Marta M Tarczyluk-Wells, Melissa M Asmar, Evan G Adintori, Roger Lawrence, Elizabeth M Snella, Jackie K Jens, Brett E Crawford, Jill C M Wait, Emma McCullagh, Jason Pinkstaff, Jonathan D Cooper, and N Matthew Ellinwood

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Brain function distinguishes female carriers and non-carriers of familial risk for autism, Adam T Eggebrecht, Ally Dworetsky, Zoë Hawks, Rebecca Coalson, Babatunde Adeyemo, Savannah Davis, Daniel Gray, Alana McMichael, Steven E Petersen, John N Constantino, and John R Pruett

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Association between immune-related adverse events and recurrence-free survival among patients with stage III melanoma randomized to receive pembrolizumab or placebo: A secondary analysis of a randomized clinical trial, Alexander M M Eggermont, Leonel Hernandez-Aya, and et al

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The current state of antifungal stewardship among pediatric antimicrobial stewardship programs, Lourdes Eguiguren, Jason G Newland, Matthew P Kronman, Adam L Hersh, Jeffrey S Gerber, Grace M Lee, and Hayden T Schwenk

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The effect of smoking during pregnancy on severity and directionality of externalizing and internalizing symptoms: A genetically informed approach, Mikael O Ekblad, Kristine Marceau, Emily Rolan, Rohan H C Palmer, Alexandre Todorov, Andrew C Heath, and Valerie S Knopik

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Long-term employment outcomes among female cancer survivors, Christine C Ekenga, Eunsun Kwon, BoRin Kim, and Sojung Park

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A prospective study of weight gain in women diagnosed with early-stage invasive breast cancer, ductal carcinoma in situ, and women without breast cancer, Christine C. Ekenga, Xiaoyan Wang, Maria Pérez, Mario Schootman, and Donna B. Jeffe

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Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis, Jennifer L. Elliott, Jenna E. Eschbach, Pratibha C. Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q. Lawson, Alan N. Engelman, Mamuka Kvaratskhelia, and Sebla B. Kutluay

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Going beyond integration: The emerging role of HIV-1 integrase in virion morphogenesis, Jennifer L Elliott and Sebla B Kutluay

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Predictors of worsening neuropathy and neuropathic pain after 12 years in people with HIV, Ronald J Ellis, Monica Diaz, Ned Sacktor, Christina Marra, Ann C Collier, David B Clifford, Nigel Calcutt, Jerel A Fields, Robert K Heaton, Scott L Letendre, and CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group

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Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects, Nirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena C Haage, Elizabeth C Wright-Jin, Alexander Schattenberg, Roxane M Papawassiliou, Helmut Kettenmann, Marcus Semtner, and David H Gutmann

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Metabolic and addiction indices in patients on opioid agonist medication-assisted treatment: A comparison of buprenorphine and methadone, Igor Elman, Margaret Howard, Jacob T. Borodovsky, David Mysels, David Rott, David Borsook, and Mark Albanese

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Chloroquine triggers cell death and inhibits PARPs in cell models of aggressive hepatoblastoma, Katja Eloranta, Stefano Cairo, Emmi Liljeström, Tea Soini, Antti Kyrönlahti, Jean-Gabriel Judde, David B Wilson, Markku Heikinheimo, and Marjut Pihlajoki

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CD46 and oncologic interactions: Friendly fire against cancer, Michelle Elvington, M Kathryn Liszewski, and John P Atkinson

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The genetic architecture of human brainstem structures and their involvement in common brain disorders, Torbjørn Elvsåshagen, Deanna M. Barch, and et al.

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Murine Surf4 is essential for early embryonic development, Brian T. Emmer, Paul J. Lascuna, Vi T. Tang, Emilee N. Kotnik, Thomas L. Saunders, Rami Khoriaty, and David Ginsburg

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A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer, Cathy Eng, Marwan Fakih, Manik Amin, Van Morris, Howard S. Hochster, Patrick M. Boland, and Hope Uronis

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Confidential genetic testing and electronic health records: A survey of current practices among Huntington disease testing centers, Celeste C Eno, Stacey K Barton, Naghmeh Dorrani, Stephen D Cederbaum, Joshua L Deignan, and Wayne W Grody

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Fenofibrate reduces the severity of neuroretinopathy in a type 2 model of diabetes without inducing peroxisome proliferator-activated receptor alpha-dependent retinal gene expression, Jennifer M Enright, Sheng Zhang, Christina Thebeau, Emily Siebert, Alexander Jin, Veda Gadiraju, Xiaodong Zhang, Shiming Chen, Clay F Semenkovich, and Rithwick Rajagopal

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Intramuscular delivery of replicon RNA encoding ZIKV-117 human monoclonal antibody protects against Zika virus infection, Jesse H. Erasmus, Jennifer Govero, Qing Tan, Lorellin A. Durnell, Michael S. Diamond, Larissa B. Thackray, and et al.

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Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation, Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C. Bucelli, Gregory F. Wu, Maxim N. Artyomov, Anne H. Cross, and Brian T. Edelson

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Nanotherapy delivery of c-myc inhibitor targets protumor macrophages and preserves antitumor macrophages in breast cancer, Alison K. Esser, Michael H. Ross, Francesca Fontana, Xinming Su, Ariel Gabay, Gregory C. Fox, Yalin Xu, Jingyu Xiang, Anne H. Schmieder, Xiaoxia Yang, Grace Cui, Michael Scott, Samuel Achilefu, Jay Chauhan, Steven Fletcher, Gregory M. Lanza, and Katherine N. Weilbaecher

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SV‑HotSpot: Detection and visualization of hotspots targeted by structural variants associated with gene expression, Abdallah M. Eteleeb, David A. Quigley, Shuang G. Zhao, Duy Pham, Rendong Yang, Scott M. Dehm, Jingqin Luo, Felix Y. Feng, Ha X. Dang, and Christopher A. Maher

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Work-related and personal factors associated with mental well-being during the COVID-19 response: Survey of health care and other workers, Bradley A Evanoff, Jaime R Strickland, Ann Marie Dale, Lisa Hayibor, Emily Page, Jennifer G Duncan, Thomas Kannampallil, and Diana L Gray

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Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin‑deficient hearts through a pathway that involves TIRAP dependent signaling, Sarah Evans, Carla J. Weinheimer, Attila Kovacs, Jesse W. Williams, Gwendalyn J. Randolph, Wenlong Jiang, Philip M. Barger, and Douglas L. Mann

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Top ten tips palliative care clinicians should know about amyotrophic lateral sclerosis, Elyse A. Everett, Elizabeth Pedowitz, Samuel Maiser, Joss Cohen, Jessica Besbris, Ambereen K. Mehta, Luqi Chi, and Christopher A. Jones

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Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation, Michael Ewers, Laura Piccio, Carlos Cruchaga, and et al

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Adherence to updated childcare nutrition regulations in Colorado, United States, Amy A Eyler, Cheryl R Valko, Katherine A Curoe, Ramya Ramadas, and Jamie F Chriqui

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Variant R94C in TNNT2‐encoded troponin T predisposes to pediatric restrictive dardiomyopathy and sudden death through impaired thin filament relaxation resulting in myocardial diastolic dysfunction, Jordan E Ezekian, Sarah R Clippinger, Jaquelin M Garcia, Qixin Yang, Susan Denfield, Aamir Jeewa, William J Dreyer, Wenxin Zou, Yuxin Fan, Hugh D Allen, Jeffrey J Kim, Michael J Greenberg, and Andrew P Landstrom

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Which metrics are being used to evaluate children and adolescents after ACL reconstruction? A systematic review, Peter D Fabricant, Christopher M Brusalis, Jonathan M Schachne, PLUTO study group, and Matthew J Matava

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Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2, José Luís Fachi, Cristiane Sécca, Blanda Di Luccia, Marco Colonna, and et al

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Cumulative exposure to long working hours and occurrence of ischemic heart disease: Evidence from the CONSTANCES cohort at inception, Marc Fadel, Jian Li, Grace Sembajwe, Diana Gagliardi, Fernando Pico, Anna Ozguler, Bradley A Evanoff, Michel Baer, Akizumi Tsutsumi, Sergio Iavicoli, Annette Leclerc, Yves Roquelaure, Johannes Siegrist, and Alexis Descatha

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Correction of respiratory artifacts in MRI head motion estimates, Damien A. Fair, Abraham Z. Snyder, Andrew N. Van, Jonathan M. Koller, Amy E. Mirro, Jacqueline M Hampton, Babatunde Adeyemo, Timothy O. Laumann, Deanna J. Greene, Deann M. Barch, Steven E. Petersen, Nico U. F. Dosenbach, and et al.

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Primary cilia as the nexus of biophysical and hedgehog signaling at the tendon enthesis, Fei Fang, Andrea G Schwartz, Emily R Moore, McKenzie E Sup, and Stavros Thomopoulos

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Biased opioid ligands, Abdelfattah Faouzi, Balazs R Varga, and Susruta Majumdar

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High-throughput analysis of adaptation using barcoded strains of Saccharomyces cerevisiae, Vincent J Fasanello, Ping Liu, Carlos A Botero, and Justin C Fay

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Validation of a Parkinson disease predictive model in a population-based study, Irene M. Faust, Brad A. Racette, and Susan Searles Nielsen

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Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma, Cinzia Federico, Kinan Alhallak, Jennifer Sun, Kathleen Duncan, Feda Azab, Gail P. Sudlow, Pilar de la Puente, Barbara Muz, Vaishali Kapoor, Luna Zhang, Fangzheng Yuan, Matea Markovic, Joseph Kotsybar, Katherine Wasden, Nicole Guenthner, Shannon Gurley, Justin King, Daniel Kohnen, Noha N. Salama, Dinesh Thotala, Dennis E. Hallahan, Ravi Vij, John F. DiPersio, Samuel Achilefu, and Abdel Kareem Azab

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Study protocol: Improving cognition in people with progressive multiple sclerosis: A multi-arm, randomized, blinded, sham-controlled trial of cognitive rehabilitation and aerobic exercise (COGEx), Anthony Feinstein, Amber Salter, and et al

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Relations between sensory responsiveness and features of autism in children, Jacob I Feldman, Margaret Cassidy, Yupeng Liu, Anne V Kirby, Mark T Wallace, and Tiffany G Woynaroski

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Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment, McKenna Feltes, Sarah E. Gale, Samantha Moores, Daniel S. Ory, and Jean E. Schaffer

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Identifying determinants of bacterial fitness in a model of human gut microbial succession, Lihui Feng, Arjun S. Raman, Matthew C. Hibberd, Jiye Cheng, Nicholas W. Griffin, Yangqing Peng, Semen A. Leyn, Dmitry A. Rodionov, Andrei L. Osterman, and Jeffrey I. Gordon

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Antipsychotic effects on cortical morphology in schizophrenia and bipolar disorders, Ruiqi Feng, Fay Y Womer, and et al

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A survey-based analysis of the academic job market, Jason D. Fernandes, Sarvenaz Sarabipour, Christopher T. Smith, Natalie M. Niemi, Nafisa M. Jadavji, Ariangela J. Kozik, Alex S. Holehouse, Vikas Pejaver, Orsolya Symmons, Alexandre W. Bisson Filho, and Amanda Haage

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Dill extract induces elastic fiber neosynthesis and functional improvement in the ascending aorta of aged mice with reversal of age-dependent cardiac hypertrophy and involvement of lysyl oxidase-like-1, Wassim Fhayli, Quentin Boëté, Nadjib Kihal, Valérie Cenizo, Pascal Sommer, Walter A Boyle, Marie-Paule Jacob, and Gilles Faury

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Lower survival after coronary artery bypass in patients who had atrial fibrillation missed by widely used definitions, Giovanni Filardo, Benjamin D Pollock, Briget da Graca, Danielle M Sass, Teresa K Phan, Debbie E Montenegro, Gorav Ailawadi, Vinod H Thourani, and Ralph J Damiano Jr

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Contraception provision in the emergency department: Are we ready to overcome the obstacles?, Kayleigh Fischer and Lauren S. Chernick

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Portable, field-based neuroimaging using high-density diffuse optical tomography, Andrew K. Fishell, Ana María Arbeláez, Claudia P. Valdés, Tracy N. Burns-Yocum, Arefeh Sherafati, Edward J. Richter, Margarita Torres, Adam T. Eggebrecht, Christopher D. Smyser, and Joseph P. Culver

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The key glycolytic enzyme phosphofructokinase is involved in resistance to antiplasmodial glycosides, Gillian M Fisher, Simon A Cobbold, Andrew Jezewski, Emma F Carpenter, Megan Arnold, Annie N Cowell, Erick T Tjhin, Kevin J Saliba, Tina S Skinner-Adams, Marcus C S Lee, Audrey Odom John, Elizabeth A Winzeler, Malcolm J McConville, Sally-Ann Poulsen, and Katherine T Andrews

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ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes, Marlie H Fisher, Gregory D Kirkpatrick, Brett Stevens, Courtney Jones, Michael Callaghan, Madhvi Rajpurkar, Joy Fulbright, Megan A Cooper, Jesse Rowley, Christopher C Porter, Arthur Gutierrez-Hartmann, Kenneth Jones, Craig Jordan, Eric M Pietras, and Jorge Di Paola

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Effectiveness of a digital cognitive behavior therapy-guided self-help intervention for eating disorders in college women: A cluster randomized clinical trial, Ellen E. Fitzsimmons-Craft, C. Barr Taylor, Andrea K. Graham, Shiri Sadeh-Sharvit, Katherine N. Balantekin, Dawn M. Eichen, Grace E. Monterubio, Neha J. Goel, Rachael E. Flatt, Anna M. Karam, Marie-Laure Firebaugh, Corinna Jacobi, Booil Jo, Mickey T. Trockel, and Denise E. Wilfley

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Repository Corticotropin Injection for Active Rheumatoid Arthritis Despite Aggressive Treatment: A Randomized Controlled Withdrawal Trial., Roy Fleischmann, Daniel E Furst, Erin Connolly-Strong, Jingyu Liu, Julie Zhu, and Richard Brasington

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Parkes Weber syndrome associated with two somatic pathogenic variants in RASA1, Josue A. Flores Daboub, Johanes F. Grimmer, Alice Frigerio, Whitney Wooderchak-Donahue, Ryan Arnold, Jeff Szymanski, Nicola Longo, and Pinar Bayrak-Toydemir

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Protective role of brain derived neurotrophic factor (BDNF) in obstructive sleep apnea syndrome (OSAS) patients, Krisstopher Richard Flores, Fausta Viccaro, Mauro Aquilini, Stefania Scarpino, Francesco Ronchetti, Rita Mancini, Arianna Di Napoli, Davide Scozzi, and Alberto Ricci

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Continuous representations of speed by striatal medium spiny neurons, Wambura C. Fobbs, Sebastiano Bariselli, Julia A. Licholai, Nanami L. Miyazaki, Bridget A. Matikainen-Ankney, Meaghan C. Creed, and Alexxai V. Kravitz

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Evolution and structure of clinically relevant gene fusions in multiple myeloma, Steven M. Foltz, Qingsong Gao, Christopher J. Yoon, Hua Sun, Lijun Yao, Yize Li, Reyka G. Jayasinghe, Song Cao, Justin King, Daniel R. Kohnen, Mark A. Fiala, Li Ding, and Ravi Vij

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Spot the difference: Comparing results of analyses from real patient data and synthetic derivatives, Randi E Foraker, Sean C Yu, Aditi Gupta, Andrew P Michelson, Jose A Pineda Soto, Ryan Colvin, Francis Loh, Marin H Kollef, Thomas Maddox, Bradley Evanoff, Hovav Dror, Noa Zamstein, Albert M Lai, and Philip R O Payne

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Emerging priorities for HIV service delivery, Nathan Ford, Elvin Geng, and et al.

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The validity and reliability of the Microsoft Kinect for measuring trunk compensation during reaching, Matthew H Foreman and Jack R Engsberg

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Combinatorial pharmacogenomic testing improves outcomes for older adults with depression, Brent P Forester, Charles R Conway, and et al

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Association of radial longitudinal deficiency and thumb hypoplasia: An update using the CoULD registry, Malka Forman, Maria F Canizares, Deborah Bohn, Michelle A James, Julie Samora, Suzanne Steinman, Lindley B Wall, Andrea S Bauer, and CoULD Study Group

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Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection, Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M Fleckenstein, James B Kaper, and Mark Donowitz

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A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice, Julie M. Fox, Ling Huang, Stephen Tahan, Laura A. Powell, James E. Crowe, David Wang, and Michael S. Diamond

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Context Is key: Delineating the unique functions of IFNα and IFNβ in disease, Lindsey E Fox, Marissa C Locke, and Deborah J Lenschow

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Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A, Antonietta Franco, Xiawei Dang, Emily K. Walton, Joshua N. Ho, Barbara Zablocka, Cindy Ly, Timothy M. Miller, Robert H. Baloh, Michael E. Shy, Andrew S. Yoo, and Gerald W. Dorn

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Alpha-crystallin mutations alter lens metabolites in mouse models of human cataracts, Cheryl Frankfater, Stephanie L. Bozeman, Fong-Fu Hsu, and Usha P. Andley

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Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma, Graeme A M Fraser, Nancy L. Bartlett, and et al

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Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts, Sharon L. Freshour, Susanna Kiwala, Kelsy C. Cotto, Adam C. Coffman, Joshua F. McMichael, Jonathan J. Song, Malachi Griffith, Obi L. Griffith, and Alex H. Wagner

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Advanced ultrasound screening for temporomandibular joint (TMJ) internal derangement, Saul N. Friedman, Miriam Grushka, Hussam K. Beituni, Madhu Rehman, Hart B. Bressler, and Lawrence Friedman

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Positron emission tomography objective parameters for assessment of left ventricular assist device infection using 18F-FDG PET/CT, Saul N Friedman, Maryam Mahmood, Jennifer R Geske, Muhammad Rizwan Sohail, Geoffrey B Johnson, John M Stulak, and Ayse Tuba Kendi

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A study protocol for a multicentre, prospective, before-and-after trial evaluating the feasibility of implementing targeted SEDation after initiation of mechanical ventilation in the emergency department (The ED-SED Pilot Trial), Brian M Fuller, Brian W Roberts, Nicholas M Mohr, Ryan D Pappal, Robert J Stephens, Yan Yan, Chris Carpenter, Marin H Kollef, and Michael Simon Avidan