The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2007

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MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent

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Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells, Alex S. Nord, Karen Vranizan, Whittemore Tingley, Alexander C. Zambon, Kristina Hanspers, Loren G. Fong, Yan Hu, Peter Bacchetti, Thomas E. Ferrin, Patricia C. Babbitt, Scott W. Doniger, William C. Skarnes, Stephen G. Young, and Bruce R. Conklin

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Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression, Lyse A. Norian and Paul M. Allen

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Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment, Carol S. North, Barry A. Hong, and David H. Alpers

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Phylogenetic diversity and microsphere array-based genotyping of human pathogenic fusaria, including isolates from the multistate contact lens-associated U.S. keratitis outbreaks of 2005 and 2006, Kerry O'Donnell, Brice A. Sarver, Mary Brandt, Douglas C. Chang, Judith Noble-Wang, Benjamin J. Park, Deanna A. Sutton, Lynette Benjamin, Mark Lindsley, Arvind Padhye, David M. Geiser, and Todd J. Ward

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Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks, Olanrewaju Okusanya, Alan Forrest, Robin DiFrancesco, Sanela Bilic, Susan Rosenkranz, Michael F. Para, Elizabeth Adams, Kevin E. Yarasheski, Richard C. Reichman, Gene D. Morse, and ACTG 5043 Protocol Team

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Shigella flexneri phagosomal escape is independent of invasion, Susanne Paetzold, Sebastian Lourido, Barbel Raupach, and Arturo Zychlinsky

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MAGED2: A novel p53-dissociator, Chris Papageorgio, Rainer Brachmann, Jue Zeng, Robert Culverhouse, Wanghai Zhang, and Howard McLeod

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The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc hermiation, Moon-Soo Park, Hwan-Mo Lee, Soo-Bong Hahn, Seong-Hwan Moon, Yung-Tae Kim, Choon-Sung Lee, Hyo-Won Jung, Byoung-Se Kwon, and K. Daniel Riew

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Site-1 protease is essential for endochondral bone formation in mice, Debabrata Patra, Xiaoyun Xing, Sherri Davies, Jennifer Bryan, Carl Franz, Ernst B. Hunziker, and Linda J. Sandell

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Toward an understanding of risk factors for anorexia nervosa: A case-control study, K. M. Pike, A. Hilbert, D. E. Wilfley, C. G. Fairburn, F. A. Dohm, B. T. Walsh, and R. Striegel-Moore

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Clinical significance of αII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, Jose A. Pineda, Stephen B. Lewis, Alex B. Valadka, Linda Papa, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Jada M. Aikman, Veronica Akle, Gretchen M. Brophy, Joseph J. Tepas III, Kevin K. W. Wang, Claudia S. Robertson, and Ronald L. Hayes

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Genetic and environmental factors affecting self-esteem from age 14 to 17: A longitudinal study of Finnish twins, Anu Raevuori, Danielle M. Dick, Anna Keski-Rahkonen, Lea Pulkkinen, Richard J. Rose, Aila Rissanen, Jaakko Kaprio, Richard J. Viken, and Karri Silventoinen

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Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivo, Ramya Rajagopal, Shunsuke Ishii, and David C. Beebe

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Polony analysis of gene expression in ES cells and blastocysts, C. Rieger, R. Poppino, R. Sheridan, K. Moley, R. Mitra, and D. Gottlieb

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Molecular refinement of gibbon genome rearrangements, Roberta Roberto, Oronzo Capozzi, Richard K. Wilson, Elaine R. Mardis, Mariana Lomiento, Eray Tuzun, Ze Cheng, Alan R. Mootnick, Nicoletta Archidiacono, Mariano Rocchi, and Evan E. Eichler

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Oxytocin in the circadian timing of birth, Jeffrey Roizen, Christina E. Luedke, Erik D. Herzog, and Louis J. Muglia

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Anionic lipids enriched at the ExPortal of Streptococcus pyogenes, Jason W. Rosch, Fong Fu Hsu, and Michael G. Caparon

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Detection of intracellular bacterial communities in human urinary tract infection, David A. Rosen, Thomas M. Hooton, Walter E. Stamm, Peter A. Humphrey, and Scott J. Hultgren

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Antiretroviral drug levels and interactions affect lipid, lipoprotein, and glucose metabolism in HIV-1 seronegative subjects: A pharmacokinetic- pharmacodynamic analysis, Susan Rosenkranz, Kevin E. Yarasheski, Michael F. Para, Richard C. Reichman, and Gene D. Morse

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Identification and characterization of small molecules that inhibit intracellular toxin transport, Jose B. Saenz, Teresa A. Doggett, and David B. Haslam

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Conduct disorder among Asians and Native Hawaiian/Pacific Islanders in the USA, J. T. Sakai, N. K. Risk, C. A. Tanaka, and R. K. Price

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GenMAPP 2: New features and resources for pathway analysis, Nathan Salomonis, Kristina Hanspers, Alexander C. Zambon, Karen Vranizan, Steven C. Lawlor, Kam D. Dahlquist, Scott W. Doniger, Josh Stuart, Bruce R. Conklin, and Alexander R. Pico

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Fine mapping of mouse QTLs for fatness using SNP data, Armin O. Schmitt, Hadi Al-Hasani, James M. Cheverud, Daniel Pomp, Lutz Bünger, and Gudrun A. Brockmann

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Increasing incidence of sterile-site infections due to non-multidrug- resistant, oxacillin-resistant Staphylococcus aureus among hospitalized patients, Garrett E. Schramm, Jennifer A. Johnson, Joshua A. Doherty, Scott T. Micek, and Marin H. Kollef

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Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: A before-after trial, Douglas J E Schuerer, Ingrid B. Borecki, David K. Warren, Victoria J. Fraser, John E. Mazuski, Walter A. Boyle, Timothy G. Buchman, Craig M. Coppersmith, and et al

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X-linked idiopathic infantile nystagmus associated with a missense mutation in FRMD7, Alan Shiels, Thomas M. Bennett, Jessica B. Prince, and Lawrence Tychsen

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DLGH1 is a negative regulator of T-lymphocyte proliferation, Linda M. Stephenson, Benedicte Sammut, Daniel B. Graham, Joaquim Chan-Wang, Karry L. Brim, Alan S. Huett, Ana V. Miletic, Tracie Kloeppel, Aimee Landry, Ramnik Xavier, and Wojciech Swat

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Correlates of stimulus-response congruence in the posterior parietal cortex, Gijsbert Stoet and Lawrence H. Snyder

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A novel mutation of the Keratin 12 gene responsible for a severe phenotype of Meesmann’s corneal dystrophy, Lori S. Sullivan, Eric B. Baylin, Ramon Font, Stephen P. Daiger, Jay S. Pepose, Thomas E. Clinch, Hisashi Nakamura, Xinping C. Zhao, and Richard W. Yee

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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice, Jiusong Sun, Galina K. Sukhova, Min Yang, Paul J. Wolters, Lindsey A. MacFarlane, Peter Libby, Chingxiu Sun, Yadong Zhang, Jian Liu, Terri L. Ennis, Rebecca Knispel, Wanfen Xiong, Robert W. Thompson, B. Timothy Baxter, and Guo-Ping Shi

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Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats, P. Suryanarayana, Megha Saraswat, J. Mark Petrash, and G. Bhanuprakash Reddy

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Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability, Elizabeth M. H. Tank, David A. Harris, Amar A. Desai, and Heather L. true

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A tale of two templates: Automatically resolving double traces has many applications, including efficient PCR-based elucidation of alternative splices, Aaron E. Tenney, Jia Qian Wu, Laura Langton, Paul Klueh, Ralph Quatrano, and Michael R. Brent

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The neuroendocrine impact of chronic stress on cancer, Premal H. Thaker, Susan K. Lutgendorf, and Anil K. Sood

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Apigenin prevents UVB-induced cyclooxygenase 2 expression: Coupled mRNA stabilization and translational inhibition, Xin Tong, Rukiyah T. Van Dross, Adnan Abu-Yousif, Aubrey R. Morrison, and Jill C. Pelling

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Vascular biology and bone formation: Hints from HIF, Dwight A. Towler

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Stable and unstable cadherin dimers: mechanisms of formation and roles in cell adhesion, Regina B. Troyanovsky, Oscar Laur, and Sergey M. Troyanovsky

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Causing and curing infantile esotropia in primates: The role of decorrelated binocular input (an American Ophthalmological Society thesis), Lawrence Tychsen

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Identification and expression of Hop, an atypical homeobox gene expressed late in lens fiber cell terminal differentiation, Oleg Vasiliev, Simon J. Rhodes, and David C. Beebe

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Metastatic disease to the breast: the Washington University experience, Aislinn Vaughan, Jill R. Dietz, Jeffrey F. Moley, Mary K. DeBenedetti, Rebecca L. Aft, William E. Gillanders, Timothy J. Eberlein, Jon Ritter, and Julie A. Margenthaler

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Prospective randomized comparison of cutting and dilating disposable trocars for access during laparoscopic renal surgery, Ramakrishna Venkatesh, Chandru P. Sundaram, Robert S. Figenshau, Yan Yan, Gerald L. Andriole, Ralph V. Clayman, and Jaime Landman

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The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation, Michele I. Vitolo, Ian E. Anglin, William M. Mahoney Jr., Keli J. Renoud, Ronald B. Gartenhaus, Kurtis E. Bachman, and Antonino Passaniti

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Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms, Suzanne E. Wahrle, Aarti R. Shah, Anne M. Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J. Thal, Alison M. Goate, and David M. Holtzman

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Age at first sexual intercourse and teenage pregnancy in Australian female twins, Mary Waldron, Andrew C. Heath, Eric Turkheimer, Robert Emery, Kathleen K. Bucholz, Pamela A.F. Madden, and Nicholas G. Martin

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Calling cards for DNA-binding proteins, Haoyi Wang, Mark Johnston, and Robi David Mitra

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Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3, Xiaoli Wang, Roger A. Herr, Wei-Jen Chua, Lonnie Lybarger, Emmanuel J.H.J. Wiertz, and Ted H. Hansen

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Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway, XiaoZhe Wang, Richard D. Kennedy, Kallol Ray, Patricia Stuckert, Tom Ellenberger, and Alan D. D'Andrea

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ABIN-3: A molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions, Brian K. Weaver, Erwin Bohn, Barbi A. Judd, M. Pilar Gil, and Robert D. Schreiber

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Analysis of surgical smoke produced by various energy-based instruments and effect on laparoscopic visibility, Kyle J. Weld, Stephen Dryer, Caroline D. Ames, Kuk Cho, Chris Hogan, Myonghwa Lee, Pratim Biswas, and Jaime Landman

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Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping, Michael C. Wendl

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Screen for genetic modifiers of stbm reveals that photoreceptor fate and rotation can be genetically uncoupled in the Drosophila eye, Tanya Wolff, Jake B. Guinto, and Amy S. Rawls

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Symposium integrating evidence-based medicine into clinical practice, Rick W. Wright, John E. Kuhn, Annunziato Amendola, Morgan H. Jones, and Kurt P. Spindler

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DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth, Chunlai Wu, Richard W. Daniels, and Aaron DiAntonio

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Inflammatory arthritis can be reined in by CpG-induced DC–NK cell cross talk, Hsin-Jung Wu, Heloisa Sawaya, Bryce Binstadt, Margot Brickelmaier, Amanda Blasius, Leonid Gorelik, Umar Mahmood, Ralph Weissleder, John Carulli, Christophe Benoist, and Diane Mathis

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An investigation of the effects of lipid-lowering medications: Genome-wide linkage analysis of lipids in the HyperGEN study, Jun Wu, Michael A. Province, Hilary Coon, Steven C. Hunt, John H. Eckfeldt, Donna K. Arnett, Gerardo Heiss, Cora E. Lewis, R Curtis Ellison, Dabeeru C. Rao, Treva Rice, and Aldi T. Kraja

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Neoplasia driven by mutant c-KIT Is mediated by intracellular, not plasma membrane, receptor signaling, Zhifu Xiang, Frederike Kreisel, Jennifer Cain, AnnaLynn Colson, and Michael H. Tomasson

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Genetic and environmental contributions to pathological gambling symptoms in a 10-year follow-up, Hong Xian, Jeffrey F. Scherrer, Wendy S. Slutske, Kamini R. Shah, Rachel Volberg, and Seth A. Eisen

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Evolution of symbiotic bacteria in the distal human intestine, Jian Xu, Michael A. Mahowald, Ruth E. Lay, Catherine A. Lozupone, Micah Hamady, Eric C. Martens, Bernard Henrissat, Pedro M. Coutinho, Patrick Minx, Philippe Latreille, Holland Cordum, Andrew Van Brunt, Kyung Kim, Robert S. Fulton, Lucinda A. Fulton, Sandra W. Clifton, Richard K. Wilson, Robin D. Knight, and Jeffrey I. Gordon

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LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival, Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Osami Kanagawa, Alec M. Cheng, Bernard Malissen, and Takashi Saito

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Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish, Chao-Tsung Yang, Anna E. Hindes, Keith A. Hultman, and Stephen L. Johnson

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Shotgun lipidomics identifies a paired rule for the presence of isomeric ether phospholipid molecular species, Kui Yang, Zhongdan Zhao, Richard W. Gross, and Xianlin Han

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Suppression of keratoepithelin and myocilin by small interfering RNAs (siRNA) in vitro, Ching Yuan, Emily J. Zins, Abbott F. Clark, and Andrew J.W. Huang

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Evidence for active maintenance of inverted repeat structures identified by a comparative genomic approach, Guoyan Zhao, Kuan Y. Chang, Katherine Varley, and Gary D. Stormo

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Identification of muscle-specific regulatory modules in Caenorhabditis elegans, Guoyan Zhao, Lawrence A. Schriefer, and Gary D. Stormo

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Coronavirus replication does not require the autophagy gene ATG5, Zijiang Zhao, Larissa B. Thackray, Brian C. Miller, Teresa M. Lynn, Michelle M. Becker, Eric Ward, Noboru N. Mizushima, Mark R. Denison, and Herbert W. Virgin

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Characterization and identification of microRNA core promoters in four model species, Xuefeng Zhou, Jianhua Ruan, Guandong Wang, and Weixiong Zhang

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UV-B responsive microRNA genes in Arabidopsis thaliana, Xuefeng Zhou, Guandong Wang, and Weixiong Zhang

Submissions from 2006

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Contrasting models of genetic co-morbidity for cannabis and other illicit drugs in adult Australian twins, A. Agrawal, M. T. Lynskey, K. K. Bucholz, N. G. Martin, P. A F Madden, and A. C. Heath

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The latent class structure of ADHD is stable across informants, Robert R. Althoff, William E. Copeland, Catherine Stanger, Eske M. Derks, Richard D. Todd, Rosalind J. Neuman, Toos C.E.M. Van Beijsterveldt, Dorret I. Boomsma, and James J. Hudziak

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Alteration in irrigant flow and deflection of flexible ureteroscopes with Nitinol baskets, Caroline D. Ames, Juan M. Perrone, Kyle J. Weld, Kelley V. Foyil, Yan Yan, Ramakrishna Venkatesh, and Jaime Landman

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Pharmacologic manipulation of the porcine ureter: Acute impact of topical drugs on ureteral diameter and peristaltic activity, Caroline D. Ames, Kyle J. Weld, Stephen T. Dryer, Greg Hruby, Scott D. Minor, Yan Yan, Robert S. Figenshau, Sam Bhayani, Jaime Landman, and Ramakrishna Venkatesh

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Evaluation of laparoscopic performance with alteration in angle of vision, Caroline Ames, Alison J. Frisella, Yan Yan, Peter Shulam, and Jaime Landman

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Cisplatin chemotherapy (without erythropoietin) and risk of life-threatening thromboembolic events in carcinoma of the uterine cervix: the tip of the iceberg? A review of the literature, Jon C. Anders, Perry W. Grigsby, and Anurag K. Singh

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GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway, Mallappa Anitha, Chetan Gondha, Roy Sutliff, Alexander Parsadanian, Simon Mwangi, Shanthi V. Sitaraman, and Shanthi Srinvasan

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Inappropriate antibiotic use in a tertiary care center in thailand: An incidence study and review of experience in Thailand, Anucha Apisarnthanarak, Somwang Danchaivijitr, Thomas C. Bailey, and Victoria J. Fraser

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Macrophages inhibit neovascularization in a murine model of age-related macular degeneration, Rajendra S. Apte, Jennifer Richter, John Herndon, and Thomas A. Ferguson

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C5a and Fcγ receptors: A mutual admiration society, John P. Atkinson

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Bypassing complement: Evolutionary lessons and future implications, John P. Atkinson and Michael M. Frank

Chronic colonization with Pandoraea apista in cystic fibrosis patients determined by repetitive-element-sequence PCR, R. M. Atkinson, J. J. LiPuma, D. B. Rosenbluth, and W. M. Dunne Jr.

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YtxR, a conserved LysR-like regulator that induces expression of genes encoding a putative ADP-ribosyltransferase toxin homologue in Yersinia enterocolitica, Grace L. Axler-DiPerte, Virginia L. Miller, and Andrew J. Darwin

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Is influenza an influenza-like illness? Clinical presentation of influenza in hospitalized patients, Hilary M. Babcock, Liana R. Merz, and Victoria J. Fraser

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Fast cloning inverted repeats for RNA interference, Sujin Bao and Ross L. Cagan

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Direct observation of a preinactivated, open state in BK channels with β2 subunits, G. Richard Benzinger, Xiao-Ming Xia, and Christopher J. Lingle

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Recent advances in basic neurosciences and brain disease: From synapses to behavior, Guo-Qiang Bi, Vadim Bolshakov, Guojun Bu, Catherine M. Cahill, Zhou-Feng Chen, Graham L. Collingridge, Robin L. Cooper, Jens R. Coorssen, Alaa El-Husseini, Vasco Galhardo, Web-Biao Gan, Jianguo Gu, Kazuhide Inoue, John Isaac, Koichi Iwata, Zhengping Jia, Bong-Kiun Kaang, Mikito Kawamata, Satoshi Kida, Eric Klann, Tatsuro Kohno, Min Li, Xiao-Jiang Li, John F. MacDonald, Karim Nader, Peter V. Nguyen, Uhtaek Oh, Ke Ren, John C. Roder, Michael W. Salter, Weihong Song, Shuzo Sugita, Shao-Jun Tang, Yuanxiang Tao, Yu Tian Wang, Newton Woo, Melanie A. Woodin, Zhen Yan, Megumu Yoshimura, Ming Xu, Zao C. Xu, Xia Zhang, Mei Zhen, and Min Zhuo

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Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes, Kumar S. Bishnupuri, Qizhi Luo, Joshua R. Korzenik, Jeffrey O. Henderson, Courtney W. Houchen, Shrikant Anant, and Brian K. Dieckgraefe

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Effect of exercise training on in vitro LDL oxidation and free radical-induced hemolysis: The HERITAGE family study, Denis Blache, Suzanne Lussier-Cacan, Jacques Gagnon, Arthur S. Leon, D.C. Rao, James S. Skinner, Jack H. Wilmore, Tuomo Rankinen, Claude Bouchard, and Jean Davignon

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Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase α-deficient mice, Frank Blaeser, Matthew J. Sanders, Nga Truong, Shanelle Ko, Long Jun Wu, David F. Wozniak, Michael S. Fanselow, Min Zhuo, and Talal A. Chatila

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Pancreatic regenerating protein (regⅠ) and regⅠreceptor mRNA are upregulated in rat pancreas after induction of acute pancreatitis, Martin H. Bluth, Sameer A. Patel, Brian K. Dieckgraefe, Hiroshi Okamoto, and Michael E. Zenilman

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A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death, Nica M. Borradaile, Kimberly K. Buhman, Laura L. Listenberger, Carolyn J. Magee, Emiko T.A. Morimoto, Daniel S. Ory, and Jean E. Schaffer

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Correlates of physical activity for adults with disability, Sarah E. Boslaugh and Elena M. Andresen

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Effective control of chronic c-herpesvirus infection by unconventional MHC class Ia–independent CD8 T cells, Douglas C. Braaten, James Scott McClellan, Ilhem Messaoudi, Scott A. Tibbetts, Kelly B. McClellan, Janko Nikolich-Zugich, and Herber W. Virgin IV

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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Symposium: Subspecialty certification: Current status of orthopaedic subspecialty certification, Keith H. Bridwell, Christopher D. Harner, David W. Polly Jr., and Peter J. Stern

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Genetic architecture of smoking behavior: A study of Finnish adult twins, Ulla Broms, Karri Silventoinen, Pamela A.F. Madden, Andrew C. Heath, and Jaakko Kaprio

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A glucose sensor in Candida albicans, Victoria Brown, Jessica A. Sexton, and Mark Johnston

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Zoom in on neurodegeneration, Guojun Bu, Huaxi Xu, and Todd E. Golde

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Use of an Ilizarov apparatus to perform closed reduction of a chronic proximal dislocation following total hip arthroplasty: A case report, R. Allen Butler, Joseph R. Hsu, and Robert L. Barrack

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Modulation of β-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family, Judy A. Cam and Guojun Bu

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Does HIV cause cardiovascular disease?, Andrew Carr and Daniel Ory