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Submissions from 2022

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FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury, Bohm Lee, Yeonsoo Oh, Eunhye Cho, Aaron DiAntonio, Valeria Cavalli, Jung Eun Shin, Hae Woong Choi, and Yongcheol Cho

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Evaluation of cisplatin-induced pathology in the larval zebrafish lateral line, David S Lee, Angela Schrader, Emily Bell, Mark E Warchol, and Lavinia Sheets

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Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ, David S Lee, Angela Schrader, Mark Warchol, and Lavinia Sheets

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A bioresorbable peripheral nerve stimulator for electronic pain block, Geumbee Lee, Emily Ray, Sabrina Genovese, Ying Yan, Arman Odabas, Umang Khandpur, Wilson Z Ray, Matthew R MacEwan, and et al.

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Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish, Hyung Joo Lee, Yiran Hou, Ju Heon Maeng, Nakul M Shah, Yujie Chen, Heather A Lawson, Hongbo Yang, Feng Yue, and Ting Wang

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The clinical spectrum of SMA-PME and in vitro normalization of its cellular ceramide profile, Michelle M Lee, Toni S Pearson, and et al.

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A novel piggyback strategy for mRNA delivery exploiting adenovirus entry biology, Myungeun Lee, Paul J Rice-Boucher, Logan Thrasher Collins, Ernst Wagner, Lorenzo Aulisa, Jeffrey Hughes, and David T Curiel

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Fluvoxamine for outpatient management of COVID-19 to prevent hospitalization: A systematic review and meta-analysis, Todd C Lee, Simone Vigod, Émilie Bortolussi-Courval, Ryan Hanula, David R Boulware, Eric J Lenze, Angela M Reiersen, and Emily G McDonald

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Community prevalence of Helicobacter pylori and dyspepsia and efficacy of triple therapy in a rural district of eastern Uganda, Yang Jae Lee, Ibrahim Ssekalo, Rauben Kazungu, Timothy S Blackwell Jr, Peter Muwereza, Yuefeng Wu, and José B Sáenz

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Bone metabolism and incretin hormones following glucose ingestion in young adults with pancreatic insufficient cystic fibrosis, Wang Shin Lei, Marissa J Kilberg, Babette S Zemel, Ronald C Rubenstein, Clea Harris, Saba Sheikh, Andrea Kelly, and Joseph M Kindler

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Associations between transcranial Doppler vasospasm and clinical outcomes after aneurysmal subarachnoid hemorrhage: A retrospective observational study, Abhijit V. Lele, Rafael Wabl, Sarah Wahlster, Jade Keen, Andrew M. Walters, Christine T. Fong, Vasu B. Dhulipala, Umeshkumar Athiraman, Anne Moore, Monica S. Vavilala, Louis J. Kim, and Michael R. Levitt

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Quantification of ovarian lesion and fallopian tube vasculature using optical-resolution photoacoustic microscopy, Xiandong Leng, Sitai Kou, Yixiao Lin, Andrea R Hagemann, Ian S Hagemann, Premal H Thaker, Lindsay M Kuroki, Carolyn K McCourt, David G Mutch, Cary Siegel, Matthew A Powell, and Quing Zhu

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Deceased donor procurement biopsy practices, interpretation, and histology-based decision-making: A survey of US kidney transplant centers, Krista L. Lentine, Jason R. Wellen, Melissa Lichtenberger, and et al.

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Digital mental health intervention plus usual care compared with usual care only and usual care plus in-person psychological counseling for orthopedic patients with symptoms of depression or anxiety: Cohort study, Ashwin J Leo, Matthew J Schuelke, Devyani M Hunt, J Philip Miller, Patricia A Areán, and Abby L Cheng

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Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills: A systematic review and meta-analysis, Noelle Le Tourneau, Ashley Germann, Ryan R. Thompson, Nathan Ford, Sheree Schwartz, Laura Beres, Aaloke Mody, Stefan Baral, Elvin H. Geng, and Ingrid Eshun-Wilson

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Stronger microstructural damage revealed in multiple sclerosis lesions with central vein sign by quantitative gradient echo MRI, Victoria A Levasseur, Biao Xiang, Amber Salter, Dmitriy A Yablonskiy, and Anne H Cross

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Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer's disease, Elizabeth Levitis, Jacob W Vogel, Thomas Funck, Vladimir Hachinski, Serge Gauthier, Jonathan Vöglein, Johannes Levin, Brian A Gordon, Tammie Benzinger, Yasser Iturria-Medina, Alan C Evans, Dominantly Inherited Alzheimer Network, and Alzheimer’s Disease Neuroimaging Initiative

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The longitudinal impact of maternal depression and neighborhood social context on adolescent mental health, Daphne Lew, Hong Xian, Travis Loux, Enbal Shacham, and Darcell Scharff

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Assessment of a novel commercial large field of view phantom for comprehensive MR imaging quality assurance of a 0.35T MRgRT system, Benjamin C Lewis, Jaeik Shin, Borna Maraghechi, Benjamin Quinn, Mike Cole, Enzo Barberi, Jin Sung Kim, Olga Green, and Taeho Kim

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Regulation of human cortical interneuron development by the chromatin remodeling protein CHD2, E M A Lewis, G Chapman, K Kaushik, J Determan, I Antony, K Meganathan, M Narasimhan, P Gontarz, B Zhang, and K L Kroll

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Effectiveness of mRNA vaccines against COVID-19 hospitalization by age and chronic medical conditions burden among immunocompetent US adults, March-August 2021, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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Effectiveness of the Ad26.COV2.S (Johnson & Johnson) coronavirus disease 2019 (COVID-19) vaccine for preventing COVID-19 hospitalizations and progression to high disease severity in the United States, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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Patients with serious injection drug use-related infections who experience patient-directed discharges on oral antibiotics have high rates of antibiotic adherence but require multidisciplinary outpatient support for retention in care, Sophia Lewis, Stephen Y. Liang, Evan S. Schwarz, David B. Liss, Rachel P. Winograd, Nathanial S. Nolan, Michael J. Durkin, and Laura R. Marks

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Racial and ethnic differences in rural-urban trends in 5-year survival of patients with lung, prostate, breast, and colorectal cancers: 1975-2011 Surveillance, Epidemiology, and End Results (SEER), Marquita W Lewis-Thames, Marvin E Langston, Saira Khan, Yunan Han, Lindsay Fuzzell, Shuai Xu, and Justin Xavier Moore

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Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer, Stephanie Lheureux, Carolyn McCourt, and et al

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Circadian pacemaker neurons display cophasic rhythms in basal calcium level and in fast calcium fluctuations, Xitong Liang, Timothy E Holy, and Paul H Taghert

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Current and future approaches to classify VUSs in LGMD-related genes, Chengcheng Li, Gabe Haller, and Conrad C Weihl

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WashU Epigenome Browser update 2022, Daofeng Li, Deepak Purushotham, Jessica K Harrison, Silas Hsu, Xiaoyu Zhuo, Changxu Fan, Shane Liu, Vincent Xu, Samuel Chen, Jason Xu, Shinyi Ouyang, Angela S Wu, and Ting Wang

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Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples, Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W Goss, Jane A O'Halloran, Philip A Mudd, and Mario Roederer

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Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19, Fuhai Li, Adrianus C M Boon, Andrew P Michelson, Randi E Foraker, Ming Zhan, and Philip R O Payne

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Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease, Fuhai Li, Abdallah M Eteleeb, William Buchser, Christopher Sohn, Guoqiao Wang, Chengjie Xiong, Philip R Payne, Eric McDade, Celeste M Karch, Oscar Harari, and Carlos Cruchaga

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Acute glycogen synthase kinase-3 inhibition modulates human cardiac conduction, Gang Li, Brittany D Brumback, Lei Huang, David M Zhang, Tiankai Yin, Catherine E Lipovsky, Stephanie C Hicks, Jesus Jimenez, Patrick M Boyle, and Stacey L Rentschler

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Reciprocal regulation of mitofusin 2-mediated mitophagy and mitochondrial fusion by different PINK1 phosphorylation events, Jiajia Li, Xiawei Dang, Antonietta Franco, and Gerald W Dorn

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Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation, Jing Li, Tripti Kumari, Andrew Barazia, Vishwanath Jha, Si-Yeon Jeong, Amber Olson, Mijeong Kim, Bum-Kyu Lee, Vijayprakash Manickam, Zhimin Song, Regina Clemens, Babak Razani, Jonghwan Kim, Mary C Dinauer, and Jaehyung Cho

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International Stroke Genetics Consortium recommendations for studies of genetics of stroke outcome and recovery, Arne G Lindgren, Jin-Moo Lee, and et al

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SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients, Frank J Lin, Alexa Michelle Altman Doss, Hannah G Davis-Adams, Lucas J Adams, Christopher H Hanson, Laura A VanBlargan, Chieh-Yu Liang, Rita E Chen, Jennifer Marie Monroy, H James Wedner, Anthony Kulczycki, Tarisa L Mantia, Caitlin C O'Shaughnessy, Saravanan Raju, Fang R Zhao, Elise Rizzi, Christopher J Rigell, Tiffany Biason Dy, Andrew L Kau, Zhen Ren, Jackson S Turner, Jane A O'Halloran, Rachel M Presti, Daved H Fremont, Peggy L Kendall, Ali H Ellebedy, Philip A Mudd, Michael S Diamond, Ofer Zimmerman, and Brian J Laidlaw

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Sustained efficacy and safety of burosumab, a monoclonal antibody to FGF23, in children with X-linked hypophosphatemia, Agnès Linglart, Erik A Imel, Michael P Whyte, Anthony A Portale, Wolfgang Högler, Annemieke M Boot, Raja Padidela, William Van't Hoff, Gary S Gottesman, Angel Chen, Alison Skrinar, Mary Scott Roberts, and Thomas O Carpenter

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Automated diagnosing primary open-angle glaucoma from fundus image by simulating human's grading with deep learning, Mingquan Lin, Bojian Hou, Lei Liu, Mae Gordon, Michael Kass, Fei Wang, Sarah H Van Tassel, and Yifan Peng

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Exit rates of accountable care organizations that serve high proportions of beneficiaries of racial and ethnic minority groups, Sunny C Lin, Karen E Joynt Maddox, Andrew M Ryan, Nicholas Moloci, Addison Shay, and John Malcolm Hollingsworth

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Depression and anxiety screening identifies patients that may benefit from treatment regardless of existing diagnoses, Brandon Lippold, Yash R. Tarkunde, Abby L. Cheng, Charles P. Hannon, Muyibat A. Adelani, and Ryan P. Calfee

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The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function, Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, and Wayne M Yokoyama

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Assessment of Apple Watch Series 6 pulse oximetry and electrocardiograms in a pediatric population, Lauren Littell, Lisa Roelle, Aarti Dalal, George F. Van Hare, William B. Orr, Nathan Miller, and Jennifer N. Avari Silva

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The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants, Chang Liu, Rita E Chen, Michael S Diamond, and et al.

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Self-esteem and weight status of young adults: Findings from a pilot study, Echu Liu and Su-Hsin Chang

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RapidPlan Hippocampal Sparing Whole Brain Model Version 2-How far can we reduce the dose?, Hefei Liu, Ryan Clark, Anthony Magliari, Robert Foster, Francisco Reynoso, Matthew Schmidt, Vinai Gondi, Christopher Abraham, Heather Curry, Patrick Kupelian, Deepak Khuntia, and Sushil Beriwal

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Real-world utilization and outcomes of systemic therapy among patients with advanced or recurrent endometrial cancer in the United States, Jinan Liu, Bruno Emond, Eric M Maiese, Marie-Hélène Lafeuille, Patrick Lefebvre, Isabelle Ghelerter, Caterina Wu, Jean A Hurteau, and Premal H Thaker

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The impact of TSC-1 and -2 mutations on response to therapy in malignant PEComa: A multicenter retrospective analysis, Lawrence Liu, Nikhil Grandhi, Yang Lyu, Xiao Zhang, Jingqin Luo, Mia Weiss, Brian Van Tine, Angela C Hirbe, and et al.

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Multisite learning of high-dimensional heterogeneous data with applications to opioid use disorder study of 15,000 patients across 5 clinical sites, Xiaokang Liu, Rui Duan, Chongliang Luo, Alexis Ogdie, Jason H Moore, Henry R Kranzler, Jiang Bian, and Yong Chen

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Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome, Zhiyi Liu, Fuyi Liao, Jihong Zhu, Dequan Zhou, Gyu Seong Heo, Hannah P. Leuhmann, Davide Scozzi, Antanisha Parks, Ramsey Hachem, Derek E. Byers, Laneshia K. Tague, Hrishikesh S. Kulkarni, Marlene Cano, Brian W. Wong, Wenjun Li, Daniel Kreisel, Andrew E Gelman, and et al.

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Spontaneous activity patterns in human motor cortex replay evoked activity patterns for hand movements, Tomer Livne, DoHyun Kim, Nicholas V Metcalf, Lu Zhang, Lorenzo Pini, Gordon L Shulman, and Maurizio Corbetta

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Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN, Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, and Rosalind A. Segal

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Mild hypoxic-ischemic encephalopathy (HIE): Timing and pattern of MRI brain injury, Yi Li, Jessica L Wisnowski, Lina Chalak, Amit M Mathur, Robert C McKinstry, Genesis Licona, Dennis E Mayock, Taeun Chang, Krisa P Van Meurs, Tai-Wei Wu, Kaashif A Ahmad, Marie-Coralie Cornet, Rakesh Rao, Aaron Scheffler, and Yvonne W Wu

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Fluorescence imaging of beta cell primary cilia, Zipeng A Li, Jung Hoon Cho, Louis G Woodhams, and Jing W Hughes

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Activation domains can decouple the mean and noise of gene expression, Kaiser Loell, Yawei Wu, Max V Staller, and Barak Cohen

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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, R J Longchamps, Mary Feitosa, Mary Wojczynski, Aldi Kraja, Michael Province, and et al.

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Discovery and characterization of potent, efficacious, orally available antimalarial Plasmepsin X inhibitors and preclinical safety assessment of UCB7362, Martin A Lowe, Daniel E Goldberg, and et al.

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The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia, Susan T Lubejko, Robert D Graham, Giulia Livrizzi, Robert Schaefer, Matthew R Banghart, and Meaghan C Creed

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Resting state network mapping in individuals using deep learning, Patrick H Luckett, John J Lee, Ki Yun Park, Ryan V Raut, Karin L Meeker, Evan M Gordon, Abraham Z Snyder, Beau M Ances, Eric C Leuthardt, and Joshua S Shimony

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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins, Cliff J Luke, Stephanie Markovina, Misty Good, Ira E Wight, Brian J Thomas, John M Linneman, Wyatt E Lanik, Olga Koroleva, Maggie R Coffman, Mark T Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L Beatty, Kelsey N Hausmann, Frances V White, James A J Fitzpatrick, Anthony Orvedahl, Stephen C Pak, and Gary A Silverman

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The association of prescription opioid use with suicide attempts: An analysis of statewide medical claims data, Chongliang Luo, Kun Chen, Riddhi Doshi, Nathaniel Rickles, Yong Chen, Harold Schwartz, and Robert H. Aseltine

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Comparability of clinical trials and spontaneous reporting data regarding COVID-19 vaccine safety, Chongliang Luo, Jingcheng Du, Adam Cuker, Ebbing Lautenbach, David A Asch, Gregory A Poland, Cui Tao, and Yong Chen

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Effectiveness and minimum effective dose of app-based mobile health interventions for anxiety and depression symptom reduction: Systematic review and meta-analysis, Sheng-Chieh Lu, Mindy Xu, Mei Wang, Angela Hardi, Abby L Cheng, Su-Hsin Chang, and Po-Yin Yen

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A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology, Brendon Lutnick, Sanjay Jain, and et al

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An RNA interference (RNAi) toolkit and its utility for functional genetic analysis of Leishmania (Viannia), Lon-Fye Lye, Katherine L Owens, Soojin Jang, Joseph E Marcus, Erin A Brettmann, and Stephen M Beverley

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Place is power: Investing in communities as a systemic leverage point to reduce breast cancer disparities by race, Matthew Jay Lyons, Senaida Fernandez Poole, Ross C Brownson, and Rodney Lyn

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Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia, Patrick G Lyons, Aaloke Mody, Alice Bewley, Katherine Dittman, Aisling Doyle, Samuel L Windham, Tej M Patel, Bharat Neelam Raju, Matthew Keller, Andrew P Michelson, Thomas Kannampallil, Elvin H Geng, Pratik Sinha, and et al.

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Parent-of-origin effects propagate through networks to shape metabolic traits, Juan F Macias-Velasco, Celine L St Pierre, Jessica P Wayhart, Li Yin, Larry Spears, Mario A Miranda, Caryn Carson, Katsuhiko Funai, James M Cheverud, Clay F Semenkovich, and Heather A Lawson

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Classical and γδ T cells are each independently sufficient to establish protection against a classical strain of Klebsiella pneumoniae, Joseph J Mackel, Catherine Morffy Smith, Rachel K Wasbotten, Joy Twentyman, and David A Rosen

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Host cell-intrinsic innate immune recognition of SARS-CoV-2, Emily A Madden and Michael S Diamond

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Socioecological predictors of breastfeeding practices in rural eastern Ethiopia, Marina Magalhães, Amanda Ojeda, Karah Mechlowitz, Kaitlin Brittain, Jenna Daniel, Kedir Teji Roba, Jemal Yousuf Hassen, Mark J Manary, Wondwossen A Gebreyes, Arie H Havelaar, and Sarah L McKune

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Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration, Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, and Celeste M Karch

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Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis, Thomas E Mahan, Chao Wang, Xin Bao, Ankit Choudhury, Jason D Ulrich, and David M Holtzman

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Epidemiology of plasmid lineages mediating the spread of extended-spectrum beta-lactamases among clinical Escherichia coli, Bejan Mahmud, Meghan A Wallace, Kimberly A Reske, Kelly Alvarado, Carol E Muenks, David A Rasmussen, Carey-Ann D Burnham, Cristina Lanzas, Erik R Dubberke, and Gautam Dantas

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Enhancing discovery of genetic variants for posttraumatic stress disorder through integration of quantitative phenotypes and trauma exposure information, Adam X. Maihofer, Andrew C. Heath, and et al.

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Multi-omics insights into the biological mechanisms underlying statistical gene-by-lifestyle interactions with smoking and alcohol consumption, Timothy D Majarian, Mary F Feitosa, Michael Province, Dabeeru C Rao, Karen Schwander, Yun Ju Sung, C Charles Gu, and et al.

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Diagnosis and management of functional tic-like phenomena, Irene A Malaty, Seonaid Anderson, Shannon M Bennett, Cathy L Budman, Barbara J Coffey, Keith A Coffman, Erica Greenberg, Joseph F McGuire, Kirsten R Müller-Vahl, Michael S Okun, Julio Quezada, Amy Robichaux-Viehoever, and Kevin J Black

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Economic evaluation of implementation science outcomes in low- and middle-income countries: A scoping review, Akash Malhotra, Abigail Barker, Victor G Davila-Roman, William Effah, and et al.

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Pharmacological chaperones for the oxytocin receptor increase oxytocin responsiveness in myometrial cells, Manasi Malik, Yingye Fang, Monali Wakle-Prabagaran, Michelle Roh, Kevin Prifti, Antonina I Frolova, Princess I Imoukhuede, and Sarah K England

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Advice from one patient to another: Qualitative analysis of patients' perspectives about chemotherapy initiation, Catalina Malinowski, Edna Paredes, Ashley J Housten, and Mariana Chavez-MacGregor

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IV sotalol use in pediatric and congenital heart patients: A multicenter registry study, Lindsey E Malloy-Walton, Nicholas H Von Bergen, Seshadri Balaji, Peter S Fischbach, Jason M Garnreiter, S Yukiko Asaki, Jeffrey P Moak, Luis A Ochoa, Philip M Chang, Hoang H Nguyen, Akash R Patel, Christa Kirk, Ashley K Sherman, Jennifer N Avari Silva, and J Philip Saul

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Activation of nano-photosensitizers by Y-90 microspheres to enhance oxidative stress and cell death in hepatocellular carcinoma, Christopher D Malone, Christopher Egbulefu, Alexander Zheleznyak, Jahnavi Polina, Partha Karmakar, Kvar Black, Monica Shokeen, and Samuel Achilefu

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Sustainability in pediatric hospitals: An exploration at the intersection of quality improvement and implementation science, Sara Malone, Jason Newland, Sapna R Kudchadkar, Kim Prewitt, Virginia McKay, Beth Prusaczyk, Enola Proctor, Ross C Brownson, and Douglas A Luke

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Fluoxetine exposure throughout neurodevelopment differentially influences basilar dendritic morphology in the motor and prefrontal cortices, Susan E Maloney, Dora R Tabachnick, Christine Jakes, Selma Avdagic, Amy L Bauernfeind, and Joseph D Dougherty

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A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice, Ryan J. Malonis, George I. Georgiev, Denise Haslwanter, Laura A. VanBlargan, Georgia Fallon, Olivia Vergnolle, Sean M. Cahill, Richard Harris, David Cowburn, Kartik Chandran, Michael S Diamond, and Jonathan R. Lai

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Longitudinal and cross-sectional validation of the WERCAP Screen for assessing psychosis risk and conversion, Daniel Mamah, Victoria N Mutiso, and David M Ndetei

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Quantitative single-cell analysis of Leishmania major amastigote differentiation demonstrates variably extended expression of the lipophosphoglycan (LPG) virulence factor in different host cell types, Michael A. Mandell, Wandy L. Beatty, and Stephen M. Beverley

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Prescribing unproven cancer drugs: Physician perspectives on expanded access and right to try, Haley Manley, Bryan A Sisk, Zubin Master, and Christopher Thomas Scott

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CDC20 regulates sensitivity to chemotherapy and radiation in glioblastoma stem cells, Diane D. Mao, Ryan T. Cleary, Amit Gujar, Tatenda Mahlokozera, and Albert H. Kim

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Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities, Natasha Marrus, Kathleen A. Koth, Jessica A. Hellings, Rachel McDonald, McLeod Frampton Gwynette, Rebecca Muhle, William D. Lohr, and Roma A. Vasa

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Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids, Michael R. Martino, Manuel Gutiérrez-Aguilar, Nicole K. H. Yiew, Andrew J. Lutkewitte, Jason M. Singer, Kyle S. McCommis, Daniel Ferguson, Kim H. H. Liss, Jun Yoshino, M. Katie Renkemeyer, Gordon I. Smith, Kevin Cho, Justin A. Fletcher, Samuel Klein, Gary J. Patti, Shawn C. Burgess, and Brian N. Finck

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p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes, Vitor F. Martins, Gretchen A. Meyer, and et al.

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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation, Etienne Masle-Farquhar, Megan A Cooper, Tiphanie P Vogel, and et al.

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First-generation and continuing-generation college graduates' application, acceptance, and matriculation to U.S. medical schools: A national cohort study, Hyacinth R C Mason, Ashar Ata, Mytien Nguyen, Sunny Nakae, Devasmita Chakraverty, Branden Eggan, Sarah Martinez, and Donna B Jeffe

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LocoMMotion: A prospective, non-interventional, multinational study of real-life current standards of care in patients with relapsed and/or refractory multiple myeloma, Maria-Victoria Mateos, Katja Weisel, Ravi Vij, and et al

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GAWMerge expands GWAS sample size and diversity by combining array-based genotyping and whole-genome sequencing, Ravi Mathur, Fang Fang, Nathan Gaddis, Dana B Hancock, Michael H Cho, John E Hokanson, Laura J Bierut, Sharon M Lutz, Kendra Young, Albert V Smith, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Edwin K Silverman, Grier P Page, and Eric O Johnson

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Local failure events in prostate cancer treated with radiotherapy: A pooled analysis of 18 randomized trials from the Meta-analysis of Randomized Trials in Cancer of the Prostate Consortium (LEVIATHAN), Ting Martin Ma, Jeff M Michalski, and et al.

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Fibroblast growth factor receptor signaling in cardiomyocytes is protective in the acute phase following ischemia-reperfusion injury, Dzmitry Matsiukevich, Stacey L House, Carla Weinheimer, Attila Kovacs, and David M Ornitz

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Radiotherapy for elderly patients with glioblastoma: An assessment of hypofractionation and modern treatment techniques, Jennifer K. Matsui, Jiayi Huang, and et al.

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Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification, Shailendra Maurya, Wei Yang, Minori Tamai, Qiang Zhang, Petra Erdmann-Gilmore, Amelia Bystry, Fernanda Martins Rodrigues, Mark C Valentine, Wing H Wong, Reid Townsend, and Todd E Druley

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TRAF2, an innate immune sensor, reciprocally regulates mitophagy and inflammation to maintain cardiac myocyte homeostasis, Xiucui Ma, David R Rawnsley, Attila Kovacs, Moydul Islam, John T Murphy, Chen Zhao, Minu Kumari, Layla Foroughi, Haiyan Liu, Kevin Qi, Aaradhya Diwan, Krzysztof Hyrc, Sarah Evans, Takashi Satoh, Brent A French, Kenneth B Margulies, Ali Javaheri, Babak Razani, Douglas L Mann, Kartik Mani, and Abhinav Diwan