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Submissions from 2022

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The role of neutrophil extracellular traps in acute lung injury, Davide Scozzi, Fuyi Liao, Alexander S Krupnick, Daniel Kreisel, and Andrew E Gelman

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Accuracy and reliability of diffusion imaging models, Nicole A. Seider, Babatunde Adeyemo, Ryland Miller, Dillan J. Newbold, Jacqueline M. Hampton, Kristen M. Scheidter, Jerrel Rutlin, Timothy O. Laumann, Jarod L. Roland, David F. Montez, Andrew N. Van, Annie Zheng, Scott Marek, Benjamin P. Kay, G. Larry Bretthorst, Yong Wang, Steven E. Petersen, Deanna M. Barch, Evan M. Gordon, Abraham Z. Snyder, Joshua S. Shimony, and Nico U. F. Dosenbach

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals, Margaret Sunitha Selvaraj, Lisa de Las Fuentes, Susan K. Dutcher, and et al.

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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication, Ghjuvan'Ghjacumu Shackleford, Yo Sasaki, and et al.

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Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers, Ami N Shah, Ashwin Sunderraj, Brian Finkelman, Sharlene H See, Andrew A Davis, Lorenzo Gerratana, Firas Wehbe, Neelima Katam, Deva Mahalingam, William J Gradishar, Amir Behdad, Luis Blanco, and Massimo Cristofanilli

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Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study, Bijal D Shah, Armin Ghobadi, and et al.

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Neutrophil-to-lymphocyte ratios in patients undergoing aortic valve replacement: The PARTNER trials and registries, Bahira Shahim, Alan Zajarias, and et al

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Severe ocrelizumab-induced enterocolitis treated successfully with ustekinumab, Janaki Shah, Ahmad Al-Taaee, Parakkal Deepak, and Anas Gremida

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Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: Updated results of the E1912 trial, Tait D Shanafelt, Amanda F Cashen, and et al.

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Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model, Riti Sharan, Allison N Bucsan, Shabaana A Khader, and et al

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Equity implications of hospital penalties during 4 years of the Comprehensive Care for Joint Replacement model, 2016 to 2019, Sukruth A Shashikumar, Andrew M Ryan, and Karen E Joynt Maddox

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Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia, Alaullah Sheikh, Brunda Tumala, Tim J Vickers, John C Martin, Bruce A Rosa, Subrata Sabui, Supratim Basu, Rita D Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D Head, Wandy Beatty, Hamid M Said, and James M Fleckenstein

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Dissemination and implementation science resources, training, and scientific activities provided through CTSA programs nationally: Opportunities to advance D&I research and training capacity, Rachel C Shelton, Rowena J Dolor, Jonathan Tobin, Ana Baumann, Catherine Rohweder, Sapana Patel, and Laura-Mae Baldwin

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Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA, Christian Shema Mugisha, Tung Dinh, Abhishek Kumar, Kasyap Tenneti, Jenna E Eschbach, Keanu Davis, Robert Gifford, Mamuka Kvaratskhelia, and Sebla B Kutluay

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The influence of green space on obesity in China: A systematic review, Jing Shen, Mengfei Li, Qianhui Wang, Ruidong Liu, Mengmeng Ji, and Ruopeng An

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TBX21 methylation as a potential regulator of immune suppression in CMS1 subtype colorectal cancer, Yuanyuan Shen, Yulia I Nussbaum, Yariswamy Manjunath, Justin J Hummel, Matthew A Ciorba, Wesley C Warren, Jussuf T Kaifi, Christos Papageorgiou, Rene Cortese, Chi-Ren Shyu, and Jonathan B Mitchem

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Bleeding and thrombotic complications associated with anticoagulation prior to lung transplantation: A case series, Hailey M. Shepherd, Ramsey R. Hachem, Chad A. Witt, Rodrigo V. Guillamet, Derek E. Byers, Benjamin D. Kozower, Bryan F. Meyers, Tsuyoshi Takahashi, G. Alexander Patterson, Varun Puri, Daniel Kreisel, and Ruben G. Nava

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CALGB 40603 (Alliance): Long-term outcomes and genomic correlates of response and survival after neoadjuvant chemotherapy with or without carboplatin and bevacizumab in triple-negative breast cancer, Jonathan H Shepherd, Cynthia Ma, and et al.

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Prefrontal cortex supports speech perception in listeners with cochlear implants, Arefeh Sherafati, Noel Dwyer, Aahana Bajracharya, Mahlega Samira Hassanpour, Adam T Eggebrecht, Jill B Firszt, Joseph P Culver, and Jonathan E Peelle

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Management of acute promyelocytic leukemia in the setting of acute COVID-19 infection, Kevin G Shim, Mallory Crain, Kristan Augustin, and Karolyn A Oetjen

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Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance, Mariko Shirane, Michael Paley, Wayne M Yokoyama, and et al.

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Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules, Yun Shi, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt, and et al.

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Durable melanoma control following disseminated talimogene laherparepvec herpetic infection, Leonid Shmuylovich, Aubriana M McEvoy, Ryan C Fields, Leonel Hernandez-Aya, George Ansstas, and David Y Chen

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Trends in matriculation from neurological surgery training programs into academic versus private practice, Neha Siddiqui, Vamsi P. Reddy, James L. Rogers, Donald K. E. Detchou, Imaima Casubhoy, Rhea Gopali, Subhang Bhalla, Mika Janbahan, Emily Morris, Meghna Priyanka Peesapati, and Nitin Agarwal

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Two cases of Wolfram syndrome who were initially diagnosed with type 1 diabetes, Francesca Silvestri, Valeria Tromba, Francesco Costantino, Nila Palaniappan, and Fumihiko Urano

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Implementation of an electronic, secure, web-based application to support routine hand hygiene observation with immediate direct feedback and anonymized benchmarking, Simon Simonet, Jonas Marschall, Rolf Kuhn, Matthias Schlegel, and Christian R Kahlert

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PARIS and SPARTA: Finding the Achilles' heel of SARS-CoV-2, Viviana Simon, Ali H Ellebedy, and et al

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Myeloid cell interferon responses correlate with clearance of SARS-CoV-2, Dhiraj K Singh, Ekaterina Aladyeva, Shibali Das, Bindu Singh, Ekaterina Esaulova, Amanda Swain, Mushtaq Ahmed, Journey Cole, Chivonne Moodley, Smriti Mehra, Larry S Schlesinger, Maxim N Artyomov, Shabaana A Khader, and Deepak Kaushal

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A unique high-output cardiac hypertrophy phenotype arising from low systemic vascular resistance in Cantu syndrome, Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, and Colin G Nichols

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Enhancing task fMRI preprocessing via individualized model-based filtering of intrinsic activity dynamics, Matthew F Singh, Anxu Wang, Michael Cole, ShiNung Ching, and Todd S Braver

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Adherence and engagement with a cognitive behavioral therapy-based conversational agent (Wysa for Chronic Pain) among adults with chronic pain: Survival analysis, Chaitali Sinha, Abby L Cheng, and Madhura Kadaba

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High temporal resolution measurements of movement reveal novel early-life physiological decline in C. elegans, Drew Benjamin Sinha and Zachary Scott Pincus

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Barriers and facilitators to diabetes screening and prevention after a pregnancy complicated by gestational diabetes, Drishti D. Sinha, Roxann C. Williams, Laura N. Hollar, Hannah R. Lucas, Bethany Johnson-Javois, Heidi B. Miller, Amanda Stoermer, Graham A. Colditz, Aimee S. James, and Cynthia J. Herrick

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Ethical, regulatory, and practical barriers to COVID-19 research: A stakeholder-informed inventory of concerns, Bryan A. Sisk, Kari Baldwin, Meredith Parsons, and James M. DuBois

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Factors affecting pathways to care for children and adolescents with complex vascular malformations: Parental perspectives, Bryan A Sisk, Anna Kerr, and Katherine A King

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers, Zachary L Skidmore, Jason Kunisaki, Yiing Lin, Kelsy C Cotto, Erica K Barnell, Jasreet Hundal, Kilannin Krysiak, Vincent Magrini, Lee Trani, Jason R Walker, Robert Fulton, Elizabeth M Brunt, Christopher A Miller, Richard K Wilson, Elaine R Mardis, Malachi Griffith, William Chapman, and Obi L Griffith

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M Smith, Angela M Verdoni, Haley J Abel, David Y Chen, Shamika Ketkar, Elizabeth R Leight, Christopher A Miller, and Timothy J Ley

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M. Smith, Angela M. Verdoni, Haley J. Abel, David Y. Chen, Shamika Ketkar, Elizabeth R. Leight, Christopher A. Miller, and Timothy J. Ley

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Opportunities to improve policy dissemination by tailoring communication materials to the research priorities of legislators, Natalie R Smith, Stephanie Mazzucca, Marissa G Hall, Kristen Hassmiller Lich, Ross C Brownson, and Leah Frerichs

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Validation of blood-based transcriptomic circadian phenotyping in older adults, S Kendall Smith, Peter Tran, Katherine A Madden, Jill Boyd, Rosemary Braun, Erik S Musiek, and Yo-El S Ju

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The Emotional Word-Emotional Face Stroop task in the ABCD study: Psychometric validation and associations with measures of cognition and psychopathology, Harry R Smolker, Kai Wang, Monica Luciana, James M Bjork, Raul Gonzalez, Deanna M Barch, Erin C McGlade, Roselinde H Kaiser, Naomi P Friedman, John K Hewitt, and Marie T Banich

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When REBOA grows wings: Resuscitative endovascular balloon occlusion of the aorta to facilitate aeromedical transport, Jason A Snyder, Douglas J E Schuerer, Grant V Bochicchio, and Mark H Hoofnagle

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Intracellular connections between basal bodies promote the coordinated behavior of motile cilia, Adam W J Soh, Louis G Woodhams, Anthony D Junker, Cassidy M Enloe, Benjamin E Noren, Adam Harned, Christopher J Westlake, Kedar Narayan, John S Oakey, Philip V Bayly, and Chad G Pearson

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JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis, Juhee Son, Shimeng Huang, Qiru Zeng, Traci L Bricker, James Brett Case, Ruochen Zang, Zhuoming Liu, Tamarand L Darling, Jian Xu, Houda H Harastani, Maria Florencia Gomez Castro, Hinissan P Kohio, Gaopeng Hou, Paul W Rothlauf, Adam L Bailey, Steven L Brody, Sean P J Whelan, Michael S Diamond, Adrianus C M Boon, Siyuan Ding, and et al

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Racial and ethnic minorities have a lower prevalence of airflow obstruction than non-Hispanic Whites, Akshay Sood, Hans Petersen, Congjian Liu, Orrin Myers, Xin Wang Shore, Bobbi A Gore, Rodrigo Vazquez-Guillamet, Linda S Cook, Paula Meek, and Yohannes Tesfaigzi

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Association of endocrine therapy initiation timeliness with adherence and continuation in low-income women with breast cancer, Nikita Sood, Ying Liu, Min Lian, Tracy Greever-Rice, Jill Lucht, Chester Schmaltz, and Graham A Colditz

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IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state, Allison L Soung, Veronica A Davé, Charise Garber, Eric D Tycksen, Lauren L Vollmer, and Robyn S Klein

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COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis, Allison L Soung, Abigail Vanderheiden, Xiaoping Jiang, Traci Bricker, Adrianus C M Boon, Robyn S Klein, and et al.

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22q11.2 Deletion Syndrome - A series of patients with midline skull base defects, Spencer S. Souza, Lia Jacobson, Dylan Chan, Anna Meyer, Jarod L. Roland, and Kimberly Luu

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De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines, Jasmin Sponagel, Siddhartha Devarakonda, Joshua B Rubin, Jingqin Luo, and Joseph E Ippolito

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Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment, Jasmin Sponagel, Jill K Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L Tinkum, Hannah Gass, Elena Nunez, Gary J Patti, Jingqin Luo, Joshua B Rubin, Joseph E Ippolito, and et al.

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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance, Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H Kim, Manish K Thakur, Muhammad A Saeed, Russell K Pachynski, Markus A Seeliger, W Todd Miller, Felix Y Feng, and Nupam P Mahajan

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Advice to clinicians on communication from adolescents and young adults with cancer and parents of children with cancer, Meghana Srinivas, Erica C Kaye, Lindsay J Blazin, Justin N Baker, Jennifer W Mack, James M DuBois, and Bryan A Sisk

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Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site, Daniel Stadlbauer, Ali H Ellebedy, and et al.

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Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains, Max V Staller, Eddie Ramirez, Sanjana R Kotha, Alex S Holehouse, Rohit V Pappu, and Barak A Cohen

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Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations, Rodrigo Tzovenos Starosta, Ying-Chen Claire Hou, Katelyn Leestma, Prapti Singh, Luke Viehl, Linda Manwaring, Jorge Luis Granadillo, Molly C Schroeder, Jamie N Colombo, Halana Whitehead, Patricia Irene Dickson, Monica L Hulbert, and Hoanh Thi Nguyen

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Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development, Neeltje Steeghs, Haeseong Park, and et al.

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Semaphorin-plexin signaling: From axonal guidance to a new X-linked intellectual disability syndrome, Jacqueline L Steele, Marwan S Shinawi, and et al.

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Implementing a new Emergency Department: A qualitative study of health professionals' change responses and perceptions, Nina Thórný Stefánsdóttir, Per Nilsen, Mette Bendtz Lindstroem, Ove Andersen, Byron J Powell, Tine Tjørnhøj-Thomsen, and Jeanette Wassar Kirk

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Left ventricular hypertrophy and biomarkers of cardiac damage and stress in aortic stenosis, Elliot J Stein, Nishath Quader, Alan Zajarias, Anna Vatterott, and et al

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Global variation in studies of articular cartilage procedures of the knee: A systematic review, R. Garrett Steinmetz, J. Jared Guth, Matthew J Matava, Matthew V Smith, and Robert H Brophy

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Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness, Meagan Stephenson, Jennie H Kwon, and et al

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A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study, Robert J Stephens, Erin M Evans, Michael J Pajor, Ryan D Pappal, Haley M Egan, Max Wei, Hunter Hayes, Jason A Morris, Nicholas Becker, Brian W Roberts, Marin H Kollef, Nicholas M Mohr, and Brian M Fuller

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Adverse events related to ultrasound-guided regional anesthesia performed by Emergency Physicians: Systematic review protocol, Sean P. Stickles, Deborah Shipley Kane, Chadd K. Kraus, Robert J. Strony, Enyo A. Ablordeppey, Michelle M. Doering, Daniel Theodoro, Jacques Simon Lee, and Christopher R. Carpenter

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Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa, Caroline Stienne, Richard Virgen-Slane, Lisa Elmén, Marisol Veny, Sarah Huang, Jennifer Nguyen, Elizabeth Chappell, Mary Olivia Balmert, Jr-Wen Shui, Michelle A Hurchla, Mitchell Kronenberg, Scott N Peterson, Kenneth M Murphy, Carl F Ware, and John R Šedý

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family, Peter J Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W D'Souza, Sanket Patel, Gautam Dantas, Gerard D Wright, and Alexei Savchenko

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Comparing antigenaemia- and microfilaraemia as criteria for stopping decisions in lymphatic filariasis elimination programmes in Africa, Wilma A. Stolk, Luc E. Coffeng, Fatorma K. Bolay, Obiora A. Eneanya, Peter U. Fischer, T. Déirdre Hollingsworth, Benjamin G. Koudou, Aboulaye Méité, Edwin Michael, Joaquin M. Prada, Rocio M. Caja Rivera, Swarnali Sharma, Panayiota Touloupou, Gary J. Weil, and Sake J. de Vlas

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Heart sparing radiotherapy techniques in breast cancer: A focus on deep inspiration breath hold, Hayley B Stowe, Neal D Andruska, Francisco Reynoso, Maria Thomas, and Carmen Bergom

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Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression, Celine L St Pierre, Juan F Macias-Velasco, Jessica P Wayhart, Li Yin, Clay F Semenkovich, and Heather A Lawson

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CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease, Jeremy F. Strain, Nicolas Barthelemy, Kanta Horie, Brian A. Gordon, Collin Kilgore, Andrew Aschenbrenner, Carlos Cruchaga, Chengjie Xiong, Nelly Joseph-Mathurin, Jason Hassenstab, Anne M. Fagan, Yan Li, Celeste M. Karch, Richard J. Perrin, Sarah B. Berman, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Hiroshi Mori, Johannes Levin, James M. Noble, Ricardo Allegri, Peter R. Schofield, Daniel S. Marcus, David M. Holtzman, John C. Morris, Tammie L. S. Benzinger, Eric M. McDade, Randall J. Bateman, and Beau M. Ances

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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease, Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Richard J. Perrin, John C. Morris, Tammie L. S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder, and et al.

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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts, Siri H Strand, Deborah J Veis, Katherine DeSchryver, Jen Tappenden, Jingqin Luo, Shu Jiang, Graham A Colditz, and et al.

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Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: The Phase III SPR1NT trial, Kevin A Strauss, Craig M Zaidman, and et al

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Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: The Phase III SPR1NT trial, Kevin A Strauss, Craig M Zaidman, and et al

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A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia, Nikki H Stricker, John L Stricker, Aimee J Karstens, Jennifer R Geske, Julie A Fields, Jason Hassenstab, Christopher G Schwarz, Nirubol Tosakulwong, Heather J Wiste, Clifford R Jack, Kejal Kantarci, and Michelle M Mielke

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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity, Madison S Strine, Mia Madel Alfajaro, Vincent R Graziano, Jaewon Song, Leon L Hsieh, Ryan Hill, Jun Guo, Kelli L VanDussen, Robert C Orchard, Megan T Baldridge, Sanghyun Lee, and Craig B Wilen

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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice, Randy Strong, Kerry Kornfeld, and et al.

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Correlating electroconvulsive therapy response to electroencephalographic markers: Study protocol, Subha Subramanian, Alyssa K Labonte, Thomas Nguyen, Anhthi H Luong, Orlandrea Hyche, S Kendall Smith, R Edward Hogan, Nuri B Farber, Ben Julian A Palanca, MohammadMehdi Kafashan, and CET-REM Study Group

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Antibiotic-resistant organisms establish reservoirs in new hospital built environments and are related to patient blood infection isolates, Kimberley V Sukhum, Erin P Newcomer, Candice Cass, Meghan A Wallace, Caitlin Johnson, Jeremy Fine, Steven Sax, Margaret H Barlet, Carey-Ann D Burnham, Gautam Dantas, and Jennie H Kwon

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India's ban on antimicrobial fixed-dose combinations: Winning the battle, losing the war?, Giorgia Sulis, Richeek Pradhan, Anita Kotwani, and Sumanth Gandra

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Exposure to World Health Organization's AWaRe antibiotics and isolation of multidrug resistant bacteria: A systematic review and meta-analysis, Giorgia Sulis, Sena Sayood, Shashi Katukoori, Neha Bollam, Ige George, Lauren H. Yaeger, Miguel A. Chavez, Emmanuel Tetteh, Sindhu Yarrabelli, Celine Pulcini, Stephan Harbarth, Dominik Mertz, Mike Sharland, Lorenzo Moja, Benedikt Huttner, and Sumanth Gandra

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Evaluation of sensitivity to endocrine herapy index (SET2,3) for response to neoadjuvant endocrine therapy and longer-term breast cancer patient outcomes (Alliance Z1031), Vera J Suman, Lili Du, Tanya Hoskin, Meenakshi Anurag, Cynthia Ma, Isabelle Bedrosian, Kelly K Hunt, Matthew J Ellis, and W Fraser Symmans

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Essential functions of MLL1 and MLL2 in retinal development and cone cell maintenance, Chi Sun, Xiaodong Zhang, Philip A Ruzycki, and Shiming Chen

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Isolation of SARS-CoV-2 in viral cell culture in immunocompromised patients with persistently positive RT-PCR results, Abby Sung, Adam L Bailey, Henry B Stewart, David McDonald, Meghan A Wallace, Kate Peacock, Candace Miller, Kimberly A Reske, Caroline A O'Neil, Victoria J Fraser, Michael S Diamond, Carey-Ann D Burnham, Hilary M Babcock, and Jennie H Kwon

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Human NK cells confer protection against HIV-1 infection in humanized mice, Can M. Sungur, Qiankun Wang, Ayşe N. Ozantürk, Hongbo Gao, Aaron J. Schmitz, Marina Cella, Wayne M. Yokoyama, and Liang Shan

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Tumor-associated macrophages in multiple myeloma: Advances in biology and therapy, Jennifer Sun, Chaelee Park, Nicole Guenthner, Shannon Gurley, Luna Zhang, Berit Lubben, Ola Adebayo, Hannah Bash, Yixuan Chen, Mina Maksimos, Barbara Muz, and Abdel Kareem Azab

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Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling, Kai Sun, Chun Wang, Jianqiu Xiao, Michael D. Brodt, Luorongxin Yuan, Tong Yang, Yael Alippe, Huimin Hu, Dingjun Hao, Yousef Abu-Amer, Matthew J. Silva, Jie Shen, and Gabriel Mbalaviele

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The multifaceted mechanisms of malignant glioblastoma progression and clinical implications, Rui Sun and Albert H Kim

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Discovery and validation of dominantly inherited Alzheimer's disease mutations in populations from Latin America, Leonel Tadao Takada, Bhagyashri D Burgute, Ellen Ziegemeier, Jennifer Petranek, Carlos Cruchaga, Maria Victoria Fernández, Eric McDade, Randall J Bateman, Celeste M Karch, Jorge J Llibre-Guerra, and et al.

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Approaches to healthcare personnel exemption requests from coronavirus disease 2019 (COVID-19) vaccination: Results of a national survey, Thomas R Talbot, Susan E Beekmann, Hilary M Babcock, and Philip M Polgreen

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Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors, Clara Sze Man Tang, Mimmi Mononen, Wai-Yee Lam, Sheng Chih Jin, Xuehan Zhuang, Maria-Mercè Garcia-Barcelo, Qiongfen Lin, Yujia Yang, Makoto Sahara, Elif Eroglu, Kenneth R. Chien, Haifa Hong, Paul Kwong Hang Tam, and Peter J. Gruber

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Generation of dual-gRNA library for combinatorial CRISPR screening of synthetic lethal gene pairs, Shan Tang, Xue Wu, Jinghui Liu, Qiongsi Zhang, Xinyi Wang, Shuai Shao, Birkan Gokbag, Kunjie Fan, Xiaoqi Liu, Fuhai Li, Lijun Cheng, and Lang Li

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Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc, Shirley N Tang, Andres F Bonilla, Nadeen O Chahine, Aimee C Colbath, Jeremiah T Easley, Sibylle Grad, Lisbet Haglund, Christine L Le Maitre, Victor Leung, Annette M McCoy, Devina Purmessur, Simon Y Tang, Stephan Zeiter, and Lachlan J Smith

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Hippocampal threat reactivity interacts with physiological arousal to predict PTSD symptoms, Büşra Tanriverdi, Stacey L House, Deanna M. Barch, and et al.

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Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease, Rawan Tarawneh, Rachel S Kasper, Jessie Sanford, Chia-Ling Phuah, Jason Hassenstab, and Carlos Cruchaga

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Enteric pathogen testing importance for children with acute gastroenteritis: A modified Delphi study, Gillian A M Tarr, Drew J Persson, Phillip I Tarr, and Stephen B Freedman