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Submissions from 2022

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Symptom-driven inhaled corticosteroid/long-acting beta-agonist therapy for adult patients with asthma who are non-adherent to daily maintenance inhalers: A study protocol for a pragmatic randomized controlled trial, James G Krings, Kaitlyn M Wojcik, Vanessa Chen, Tejas C Sekhar, Kelly Harris, Abigail Zulich, Kaharu Sumino, Ross Brownson, Eric Lenze, and Mario Castro

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Stroke recovery phenotyping through network trajectory approaches and graph neural networks, Sanjukta Krishnagopal, Keith Lohse, and Robynne Braun

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A phase II trial of an alternative schedule of palbociclib and embedded serum TK1 analysis, Jairam Krishnamurthy, Jingqin Luo, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Anna Roshal, Mathew Cherian, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Lindsey Peterson, Cynthia X Ma, and et al

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Sickle Cell Transplantation Evaluation of Long-term and Late Effects Registry (STELLAR) to compare long-term outcomes after hematopoietic cell transplantation to those in siblings without sickle cell disease and in nontransplanted individuals with sickle cell disease: Design and feasibility study, Lakshmanan Krishnamurti, Shalini Shenoy, and Et al

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Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD, Gopinath Krishnan, Timothy M Miller, and et al

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Management of diarrhea in patients with HER2-positive breast cancer treated with neratinib: A case series and summary of the literature, Megan L Kruse, Irene M Kang, Nusayba A Bagegni, W Todd Howell, Halle C F Moore, Cynthia H Bedell, and Christopher T Stokoe

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Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy, Kelsey L Krus, Amy Strickland, Yurie Yamada, Laura Devault, Robert E Schmidt, A Joseph Bloom, Jeffrey Milbrandt, and Aaron DiAntonio

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Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates, F Matthew Kuhlmann, Phillip N Key, Suzanne M Hickerson, John Turk, Fong-Fu Hsu, and Stephen M Beverley

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The human male liver is predisposed to inflammation via enhanced myeloid responses to inflammatory triggers, Adrian Kuipery, Deeqa Mahamed, Shirin Nkongolo, June Ann D'Angelo, Alexandra Johnson Valiente, Aman Mehrotra, William C Chapman, Peter Horton, Ian McGilvray, Harry L A Janssen, and Adam J Gehring

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Automated measurement of net water uptake from baseline and follow-up CTs in patients with large vessel occlusion stroke, Atul Kumar, Yasheng Chen, Aaron Corbin, Ali Hamzehloo, Amin Abedini, Zeynep Vardar, Grace Carey, Kunal Bhatia, Laura Heitsch, Jamal J Derakhshan, Jin-Moo Lee, and Rajat Dhar

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It's getting complicated-A fresh look at p53-MDM2-ARF triangle in tumorigenesis and cancer therapy, Che-Pei Kung and Jason D Weber

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A randomized controlled trial in schools aimed at exploring mechanisms of change of a multifaceted implementation strategy for promoting mental health at the workplace, Lydia Kwak, Anna Toropova, Byron J Powell, Rebecca Lengnick-Hall, Irene Jensen, Gunnar Bergström, Liselotte Schäfer Elinder, Kjerstin Stigmar, Charlotte Wåhlin, and Christina Björklund

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Clinical and occupational risk factors for coronavirus disease 2019 (COVID-19) in healthcare personnel, Jennie H. Kwon, Philip J. Budge, Caroline A. O'Neil, Kate Peacock, Eva M. Aagaard, Victoria J. Fraser, Margaret A. Olsen, and Hilary Babcock

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Echocardiographic and clinical predictors of cardiac amyloidosis: Limitations of apical sparing, Douglas Kyrouac, Walter Schiffer, Brandon Lennep, Nicole Fergestrom, Kathleen W Zhang, John Gorcsan III, Daniel J Lenihan, and Joshua D Mitchell

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Projected effects of disruptions to human immunodeficiency virus (HIV) prevention services during the coronavirus disease 2019 pandemic among Black/African American men who have sex with men in an Ending the HIV Epidemic priority jurisdiction, Jennifer Labs, Amy S Nunn, Philip A Chan, S Bessey, Carolyn J Park, Brandon D L Marshall, Rupa R Patel, Leandro A Mena, and William C Goedel

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Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans, Dongbing Lai, Arpana Agrawal, and et al

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Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes, Matthew Lalli, Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen, Jeffrey Milbrandt, Joseph D Dougherty, and Robi D Mitra

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Mass drug administration of ivermectin, diethylcarbamazine, plus albendazole compared with diethylcarbamazine plus albendazole for reduction of lymphatic filariasis endemicity in Papua New Guinea: A cluster-randomised trial, Moses Laman, Gary J Weil, and et al.

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Non-sedative cortical EEG signatures of allopregnanolone and functional comparators, Peter M Lambert, Richard Ni, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, and Steven Mennerick

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Delay of gratification dissociates cognitive control and valuation brain regions in healthy young adults, Bidhan Lamichhane, Elisa Di Rosa, and Todd S Braver

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Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology, Max Lam, Chia-Yen Chen, W David Hill, Charley Xia, Ruoyu Tian, Daniel F Levey, Joel Gelernter, Murray B Stein, Alexander S Hatoum, Hailiang Huang, Anil K Malhotra, Heiko Runz, Tian Ge, and Todd Lencz

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Assessment of ethno-racial and insurance-based disparities in pediatric forearm and tibial fracture care in the United States, Andrew J Landau, Afolayan K Oladeji, and Pooya Hosseinzadeh

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Implementation of a provider-focused intervention for maximizing human papillomavirus (HPV) vaccine uptake in young cancer survivors receiving follow-up care in pediatric oncology practices: Protocol for a cluster-randomized trial of the HPV PROTECT intervention, Wendy Landier, Smita Bhatia, Joshua S Richman, Paula D Campos Gonzalez, Brooke Cherven, Veronica Chollette, Jamie Aye, Sharon M Castellino, Maria M Gramatges, Susan Lindemulder, Thomas B Russell, Lucie M Turcotte, Graham A Colditz, Melissa B Gilkey, and James L Klosky

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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis, Brandon M. Lane, Andrew F. Malone, and et al.

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Serologic and cytokine signatures in children with multisystem inflammatory syndrome and coronavirus disease 2019, Stacey A. Lapp, Carol M. Kao, David A. Hunstad, and et al

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The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems, Keren Lasker, Steven Boeynaems, Vinson Lam, Daniel Scholl, Emma Stainton, Adam Briner, Maarten Jacquemyn, Dirk Daelemans, Ashok Deniz, Elizabeth Villa, Alex S Holehouse, Aaron D Gitler, and Lucy Shapiro

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Efficacy and safety of bempedoic acid in patients not receiving statins in phase 3 clinical trials, Ulrich Laufs, Christie M Ballantyne, Maciej Banach, Harold Bays, Alberico L Catapano, P Barton Duell, Anne C Goldberg, Antonio M Gotto, Lawrence A Leiter, Kausik K Ray, LeAnne T Bloedon, Diane MacDougall, Yang Zhang, and G B John Mancini

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Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: Prospective observational study, Adam S Lauring, Hilary M Babcock, Jennie H Kwon, and et al

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Gene-lifestyle interactions in the genomics of human complex traits, Vincent Laville, Yun J Sung, Karen Schwander, Mary F Feitosa, Aldi T Kraja, Mike Province, C Charles Gu, D C Rao, and et al

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Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry, Dylan Lawrence, Danielle E Campbell, Lawrence A Schriefer, Rachel Rodgers, Forrest C Walker, Marissa Turkin, Lindsay Droit, Miles Parkes, Scott A Handley, and Megan T Baldridge

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Prenatal exposure to maternal social disadvantage and psychosocial stress and neonatal white matter connectivity at birth, Rachel E Lean, Christopher D Smyser, Rebecca G Brady, Regina L Triplett, Sydney Kaplan, Jeanette K Kenley, Joshua S Shimony, Tara A Smyser, J Phillip Miller, Deanna M Barch, Joan L Luby, Barbara B Warner, and Cynthia E Rogers

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Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum: A case series and systematic literature review, Michael T. LeCompte, Brandon Mason, Keenan J. Robbins, Matoya Yano, Deyali Chatterjee, Ryan C. Fields, Steven M. Strasberg, and William G. Hawkins

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FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury, Bohm Lee, Yeonsoo Oh, Eunhye Cho, Aaron DiAntonio, Valeria Cavalli, Jung Eun Shin, Hae Woong Choi, and Yongcheol Cho

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Integrating a patient decision aid into the electronic health record: A case report on the implementation of BREASTChoice at 2 sites, Clara N Lee, Janessa Sullivan, Randi Foraker, Terence M Myckatyn, Margaret A Olsen, Crystal Phommasathit, Jessica Boateng, Katelyn L Parrish, Milisa Rizer, Tim Huerta, and Mary C Politi

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Evaluation of cisplatin-induced pathology in the larval zebrafish lateral line, David S Lee, Angela Schrader, Emily Bell, Mark E Warchol, and Lavinia Sheets

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Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ, David S Lee, Angela Schrader, Mark Warchol, and Lavinia Sheets

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A bioresorbable peripheral nerve stimulator for electronic pain block, Geumbee Lee, Emily Ray, Sabrina Genovese, Ying Yan, Arman Odabas, Umang Khandpur, Wilson Z Ray, Matthew R MacEwan, and et al.

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Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish, Hyung Joo Lee, Yiran Hou, Ju Heon Maeng, Nakul M Shah, Yujie Chen, Heather A Lawson, Hongbo Yang, Feng Yue, and Ting Wang

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The clinical spectrum of SMA-PME and in vitro normalization of its cellular ceramide profile, Michelle M Lee, Toni S Pearson, and et al.

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A novel piggyback strategy for mRNA delivery exploiting adenovirus entry biology, Myungeun Lee, Paul J Rice-Boucher, Logan Thrasher Collins, Ernst Wagner, Lorenzo Aulisa, Jeffrey Hughes, and David T Curiel

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Fluvoxamine for outpatient management of COVID-19 to prevent hospitalization: A systematic review and meta-analysis, Todd C Lee, Simone Vigod, Émilie Bortolussi-Courval, Ryan Hanula, David R Boulware, Eric J Lenze, Angela M Reiersen, and Emily G McDonald

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Community prevalence of Helicobacter pylori and dyspepsia and efficacy of triple therapy in a rural district of eastern Uganda, Yang Jae Lee, Ibrahim Ssekalo, Rauben Kazungu, Timothy S Blackwell Jr, Peter Muwereza, Yuefeng Wu, and José B Sáenz

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Bone metabolism and incretin hormones following glucose ingestion in young adults with pancreatic insufficient cystic fibrosis, Wang Shin Lei, Marissa J Kilberg, Babette S Zemel, Ronald C Rubenstein, Clea Harris, Saba Sheikh, Andrea Kelly, and Joseph M Kindler

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Transient hiatal separation during straight leg raise can predict reflux burden in gastroesophageal reflux disease patients with ineffective esophageal motility, Wei-Yi Lei, Shu-Wei Liang, Taher Omari, Wei-Chuan Chang, Ming-Wun Wong, Jui-Sheng Hung, Chih-Hsun Yi, Tso-Tsai Liu, Lin Lin, C Prakash Gyawali, and Chien-Lin Chen

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Associations between transcranial Doppler vasospasm and clinical outcomes after aneurysmal subarachnoid hemorrhage: A retrospective observational study, Abhijit V. Lele, Rafael Wabl, Sarah Wahlster, Jade Keen, Andrew M. Walters, Christine T. Fong, Vasu B. Dhulipala, Umeshkumar Athiraman, Anne Moore, Monica S. Vavilala, Louis J. Kim, and Michael R. Levitt

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Quantification of ovarian lesion and fallopian tube vasculature using optical-resolution photoacoustic microscopy, Xiandong Leng, Sitai Kou, Yixiao Lin, Andrea R Hagemann, Ian S Hagemann, Premal H Thaker, Lindsay M Kuroki, Carolyn K McCourt, David G Mutch, Cary Siegel, Matthew A Powell, and Quing Zhu

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Deceased donor procurement biopsy practices, interpretation, and histology-based decision-making: A survey of US kidney transplant centers, Krista L. Lentine, Jason R. Wellen, Melissa Lichtenberger, and et al.

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Digital mental health intervention plus usual care compared with usual care only and usual care plus in-person psychological counseling for orthopedic patients with symptoms of depression or anxiety: Cohort study, Ashwin J Leo, Matthew J Schuelke, Devyani M Hunt, J Philip Miller, Patricia A Areán, and Abby L Cheng

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Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills: A systematic review and meta-analysis, Noelle Le Tourneau, Ashley Germann, Ryan R. Thompson, Nathan Ford, Sheree Schwartz, Laura Beres, Aaloke Mody, Stefan Baral, Elvin H. Geng, and Ingrid Eshun-Wilson

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Stronger microstructural damage revealed in multiple sclerosis lesions with central vein sign by quantitative gradient echo MRI, Victoria A Levasseur, Biao Xiang, Amber Salter, Dmitriy A Yablonskiy, and Anne H Cross

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Differentiating amyloid beta spread in autosomal dominant and sporadic Alzheimer's disease, Elizabeth Levitis, Jacob W Vogel, Thomas Funck, Vladimir Hachinski, Serge Gauthier, Jonathan Vöglein, Johannes Levin, Brian A Gordon, Tammie Benzinger, Yasser Iturria-Medina, Alan C Evans, Dominantly Inherited Alzheimer Network, and Alzheimer’s Disease Neuroimaging Initiative

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The longitudinal impact of maternal depression and neighborhood social context on adolescent mental health, Daphne Lew, Hong Xian, Travis Loux, Enbal Shacham, and Darcell Scharff

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Assessment of a novel commercial large field of view phantom for comprehensive MR imaging quality assurance of a 0.35T MRgRT system, Benjamin C Lewis, Jaeik Shin, Borna Maraghechi, Benjamin Quinn, Mike Cole, Enzo Barberi, Jin Sung Kim, Olga Green, and Taeho Kim

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Regulation of human cortical interneuron development by the chromatin remodeling protein CHD2, E M A Lewis, G Chapman, K Kaushik, J Determan, I Antony, K Meganathan, M Narasimhan, P Gontarz, B Zhang, and K L Kroll

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Effectiveness of mRNA vaccines against COVID-19 hospitalization by age and chronic medical conditions burden among immunocompetent US adults, March-August 2021, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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Effectiveness of the Ad26.COV2.S (Johnson & Johnson) coronavirus disease 2019 (COVID-19) vaccine for preventing COVID-19 hospitalizations and progression to high disease severity in the United States, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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Patients with serious injection drug use-related infections who experience patient-directed discharges on oral antibiotics have high rates of antibiotic adherence but require multidisciplinary outpatient support for retention in care, Sophia Lewis, Stephen Y. Liang, Evan S. Schwarz, David B. Liss, Rachel P. Winograd, Nathanial S. Nolan, Michael J. Durkin, and Laura R. Marks

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Racial and ethnic differences in rural-urban trends in 5-year survival of patients with lung, prostate, breast, and colorectal cancers: 1975-2011 Surveillance, Epidemiology, and End Results (SEER), Marquita W Lewis-Thames, Marvin E Langston, Saira Khan, Yunan Han, Lindsay Fuzzell, Shuai Xu, and Justin Xavier Moore

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Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer, Stephanie Lheureux, Carolyn McCourt, and et al

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Perspectives of participation in daily life from cancer survivors: A qualitative analysis, Allison J L'Hotta, Nirmala Shivakumar, Kathleen D Lyons, Audrey Trebelhorn, Annamayil Manohar, and Allison A King

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Circadian pacemaker neurons display cophasic rhythms in basal calcium level and in fast calcium fluctuations, Xitong Liang, Timothy E Holy, and Paul H Taghert

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Current and future approaches to classify VUSs in LGMD-related genes, Chengcheng Li, Gabe Haller, and Conrad C Weihl

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WashU Epigenome Browser update 2022, Daofeng Li, Deepak Purushotham, Jessica K Harrison, Silas Hsu, Xiaoyu Zhuo, Changxu Fan, Shane Liu, Vincent Xu, Samuel Chen, Jason Xu, Shinyi Ouyang, Angela S Wu, and Ting Wang

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Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples, Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W Goss, Jane A O'Halloran, Philip A Mudd, and Mario Roederer

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Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19, Fuhai Li, Adrianus C M Boon, Andrew P Michelson, Randi E Foraker, Ming Zhan, and Philip R O Payne

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Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease, Fuhai Li, Abdallah M Eteleeb, William Buchser, Christopher Sohn, Guoqiao Wang, Chengjie Xiong, Philip R Payne, Eric McDade, Celeste M Karch, Oscar Harari, and Carlos Cruchaga

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Acute glycogen synthase kinase-3 inhibition modulates human cardiac conduction, Gang Li, Brittany D Brumback, Lei Huang, David M Zhang, Tiankai Yin, Catherine E Lipovsky, Stephanie C Hicks, Jesus Jimenez, Patrick M Boyle, and Stacey L Rentschler

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Reciprocal regulation of mitofusin 2-mediated mitophagy and mitochondrial fusion by different PINK1 phosphorylation events, Jiajia Li, Xiawei Dang, Antonietta Franco, and Gerald W Dorn

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Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation, Jing Li, Tripti Kumari, Andrew Barazia, Vishwanath Jha, Si-Yeon Jeong, Amber Olson, Mijeong Kim, Bum-Kyu Lee, Vijayprakash Manickam, Zhimin Song, Regina Clemens, Babak Razani, Jonghwan Kim, Mary C Dinauer, and Jaehyung Cho

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International Stroke Genetics Consortium recommendations for studies of genetics of stroke outcome and recovery, Arne G Lindgren, Jin-Moo Lee, and et al

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SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients, Frank J Lin, Alexa Michelle Altman Doss, Hannah G Davis-Adams, Lucas J Adams, Christopher H Hanson, Laura A VanBlargan, Chieh-Yu Liang, Rita E Chen, Jennifer Marie Monroy, H James Wedner, Anthony Kulczycki, Tarisa L Mantia, Caitlin C O'Shaughnessy, Saravanan Raju, Fang R Zhao, Elise Rizzi, Christopher J Rigell, Tiffany Biason Dy, Andrew L Kau, Zhen Ren, Jackson S Turner, Jane A O'Halloran, Rachel M Presti, Daved H Fremont, Peggy L Kendall, Ali H Ellebedy, Philip A Mudd, Michael S Diamond, Ofer Zimmerman, and Brian J Laidlaw

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Sustained efficacy and safety of burosumab, a monoclonal antibody to FGF23, in children with X-linked hypophosphatemia, Agnès Linglart, Erik A Imel, Michael P Whyte, Anthony A Portale, Wolfgang Högler, Annemieke M Boot, Raja Padidela, William Van't Hoff, Gary S Gottesman, Angel Chen, Alison Skrinar, Mary Scott Roberts, and Thomas O Carpenter

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Automated diagnosing primary open-angle glaucoma from fundus image by simulating human's grading with deep learning, Mingquan Lin, Bojian Hou, Lei Liu, Mae Gordon, Michael Kass, Fei Wang, Sarah H Van Tassel, and Yifan Peng

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Primary open-angle glaucoma diagnosis from optic disc photographs using a Siamese network, Mingquan Lin, Lei Liu, Mae Gordon, Michael Kass, Fei Wang, Sarah H Van Tassel, and Yifan Peng

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Exit rates of accountable care organizations that serve high proportions of beneficiaries of racial and ethnic minority groups, Sunny C Lin, Karen E Joynt Maddox, Andrew M Ryan, Nicholas Moloci, Addison Shay, and John Malcolm Hollingsworth

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Depression and anxiety screening identifies patients that may benefit from treatment regardless of existing diagnoses, Brandon Lippold, Yash R. Tarkunde, Abby L. Cheng, Charles P. Hannon, Muyibat A. Adelani, and Ryan P. Calfee

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The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function, Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, and Wayne M Yokoyama

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Assessment of Apple Watch Series 6 pulse oximetry and electrocardiograms in a pediatric population, Lauren Littell, Lisa Roelle, Aarti Dalal, George F. Van Hare, William B. Orr, Nathan Miller, and Jennifer N. Avari Silva

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The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants, Chang Liu, Rita E Chen, Michael S Diamond, and et al.

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Self-esteem and weight status of young adults: Findings from a pilot study, Echu Liu and Su-Hsin Chang

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RapidPlan Hippocampal Sparing Whole Brain Model Version 2-How far can we reduce the dose?, Hefei Liu, Ryan Clark, Anthony Magliari, Robert Foster, Francisco Reynoso, Matthew Schmidt, Vinai Gondi, Christopher Abraham, Heather Curry, Patrick Kupelian, Deepak Khuntia, and Sushil Beriwal

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Real-world utilization and outcomes of systemic therapy among patients with advanced or recurrent endometrial cancer in the United States, Jinan Liu, Bruno Emond, Eric M Maiese, Marie-Hélène Lafeuille, Patrick Lefebvre, Isabelle Ghelerter, Caterina Wu, Jean A Hurteau, and Premal H Thaker

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The impact of TSC-1 and -2 mutations on response to therapy in malignant PEComa: A multicenter retrospective analysis, Lawrence Liu, Nikhil Grandhi, Yang Lyu, Xiao Zhang, Jingqin Luo, Mia Weiss, Brian Van Tine, Angela C Hirbe, and et al.

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Multisite learning of high-dimensional heterogeneous data with applications to opioid use disorder study of 15,000 patients across 5 clinical sites, Xiaokang Liu, Rui Duan, Chongliang Luo, Alexis Ogdie, Jason H Moore, Henry R Kranzler, Jiang Bian, and Yong Chen

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Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome, Zhiyi Liu, Fuyi Liao, Jihong Zhu, Dequan Zhou, Gyu Seong Heo, Hannah P. Leuhmann, Davide Scozzi, Antanisha Parks, Ramsey Hachem, Derek E. Byers, Laneshia K. Tague, Hrishikesh S. Kulkarni, Marlene Cano, Brian W. Wong, Wenjun Li, Daniel Kreisel, Andrew E Gelman, and et al.

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Spontaneous activity patterns in human motor cortex replay evoked activity patterns for hand movements, Tomer Livne, DoHyun Kim, Nicholas V Metcalf, Lu Zhang, Lorenzo Pini, Gordon L Shulman, and Maurizio Corbetta

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Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN, Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, and Rosalind A. Segal

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Mild hypoxic-ischemic encephalopathy (HIE): Timing and pattern of MRI brain injury, Yi Li, Jessica L Wisnowski, Lina Chalak, Amit M Mathur, Robert C McKinstry, Genesis Licona, Dennis E Mayock, Taeun Chang, Krisa P Van Meurs, Tai-Wei Wu, Kaashif A Ahmad, Marie-Coralie Cornet, Rakesh Rao, Aaron Scheffler, and Yvonne W Wu

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Fluorescence imaging of beta cell primary cilia, Zipeng A Li, Jung Hoon Cho, Louis G Woodhams, and Jing W Hughes

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Activation domains can decouple the mean and noise of gene expression, Kaiser Loell, Yawei Wu, Max V Staller, and Barak Cohen

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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, R J Longchamps, Mary Feitosa, Mary Wojczynski, Aldi Kraja, Michael Province, and et al.

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Discovery and characterization of potent, efficacious, orally available antimalarial Plasmepsin X inhibitors and preclinical safety assessment of UCB7362, Martin A Lowe, Daniel E Goldberg, and et al.

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The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia, Susan T Lubejko, Robert D Graham, Giulia Livrizzi, Robert Schaefer, Matthew R Banghart, and Meaghan C Creed

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Environmental conditions to promote healthy childhood brain/behavioral development: Informing early preventive interventions for delivery in routine care, Joan L Luby, Cynthia Rogers, and Katie A McLaughlin

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Resting state network mapping in individuals using deep learning, Patrick H Luckett, John J Lee, Ki Yun Park, Ryan V Raut, Karin L Meeker, Evan M Gordon, Abraham Z Snyder, Beau M Ances, Eric C Leuthardt, and Joshua S Shimony

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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins, Cliff J Luke, Stephanie Markovina, Misty Good, Ira E Wight, Brian J Thomas, John M Linneman, Wyatt E Lanik, Olga Koroleva, Maggie R Coffman, Mark T Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L Beatty, Kelsey N Hausmann, Frances V White, James A J Fitzpatrick, Anthony Orvedahl, Stephen C Pak, and Gary A Silverman

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The association of prescription opioid use with suicide attempts: An analysis of statewide medical claims data, Chongliang Luo, Kun Chen, Riddhi Doshi, Nathaniel Rickles, Yong Chen, Harold Schwartz, and Robert H. Aseltine

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Comparability of clinical trials and spontaneous reporting data regarding COVID-19 vaccine safety, Chongliang Luo, Jingcheng Du, Adam Cuker, Ebbing Lautenbach, David A Asch, Gregory A Poland, Cui Tao, and Yong Chen

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Effectiveness and minimum effective dose of app-based mobile health interventions for anxiety and depression symptom reduction: Systematic review and meta-analysis, Sheng-Chieh Lu, Mindy Xu, Mei Wang, Angela Hardi, Abby L Cheng, Su-Hsin Chang, and Po-Yin Yen

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A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology, Brendon Lutnick, Sanjay Jain, and et al