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Submissions from 2020

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T follicular helper phenotype predicts response to histone deacetylase inhibitors in relapsed/refractory peripheral T-cell lymphoma, Paola Ghione, Neha Mehta-Shah, Shakthi Bhaskar, and et al.

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The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: The Colocare Study, Biljana Gigic, Graham A Colditz, Adetunji T Toriola, and et al

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Radically open dialectical behavior therapy: Social signaling, transdiagnostic utility and current evidence, Kirsten Gilbert, Karyn Hall, and R Trent Codd

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Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma, Michael A. Gillette, Song Cao, Yize Li, Wen-Wei Liang, Michael C Wendl, Ramaswamy Govindan, and et al.

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Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months, Jessica B Girault, Kelly N Botteron, John N Constantino, and et al

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Assessment of plasma amyloid-β42/40 and cognitive decline among community-dwelling older adults, Kelly Virecoulon Giudici, Philipe de Souto Barreto, Sophie Guyonnet, Yan Li, Randall J. Bateman, and Bruno Vellas

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Trends in Diagnosis Related Groups for inpatient admissions and associated changes in payment from 2012 to 2016, Ty J. Gluckman, Kateri J. Spinelli, Mansen Wang, Amir Yazdani, Gary Grunkemeier, Steven M. Bradley, Jason H. Wasfy, Abhinav Goyal, Andrew Oseran, and Karen E. Joynt Maddox

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Characterization of a multicenter pediatric-hydrocephalus shunt biobank, Jacob Gluski, Paul Zajciw, Prashant Hariharan, Amanda Morgan, Diego M Morales, Andrew Jea, William Whitehead, Neena Marupudi, Steven Ham, Sandeep Sood, James P McAllister II, David D Limbrick Jr, and Carolyn A Harris

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Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser, Keerthana Gnanapradeepan, Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V. Lee, William J. Quinn, Che-Pei Kung, Rexford Ahima, Joseph A. Baur, Kathryn E. Wellen, Qin Liu, Zachary T. Schug, Donna L. George, and Maureen E. Murphy

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Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1, Abigail Godec, Reyka Jayasinghe, John S A Chrisinger, Bethany Prudner, Tyler Ball, Yuxi Wang, Divya Srihari, Madhurima Kaushal, Hilary Dietz, Xiaochun Zhang, Melike Pekmezci, Sonika Dahiya, Yu Tao, Jinqin Luo, Brian A Van Tine, Li Ding, David H Gutmann, and Angela C Hirbe

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A retrospective analysis of clinical use of alirocumab in lipoprotein apheresis patients, Anne C Goldberg, Richard L Dunbar, Linda Hemphill, Stephan P Babirak, Gerald Wilson, Michael Wooten, Mohamed Iydroose, Kelley Dacus, Heather Minchew, Julie-Ann Dutton, and Patrick M Moriarty

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Hardly vacuous: The parasitophorous vacuolar membrane of malaria parasites, Daniel E Goldberg and Joshua Zimmerberg

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Hematopoeitic cell transplantation and CAR T-cell therapy: Complements or competitors?, Scott R Goldsmith, Armin Ghobadi, and John F DiPersio

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Comparison of differential accessibility analysis strategies for ATAC-seq data, Paul Gontarz, Shuhua Fu, Xiaoyun Xing, Shaopeng Liu, Benpeng Miao, Viktoriia Bazylianska, Akhil Sharma, Pamela Madden, Kitra Cates, Andrew Yoo, Anna Moszczynska, Ting Wang, and Bo Zhang

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The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain, Jared V. Goodman, Tomoko Yamada, Yue Yang, Lingchun Kong, Dennis Y. Wu, Guoyan Zhao, Harrison W. Gabel, and Azad Bonni

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Reaching consensus on principles of stakeholder engagement in research, Melody S. Goodman, Nicole Ackermann, Deborah J. Bowen, members of the Delphi panel, and Vetta Sanders Thompson

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Lactate-protechypoglycemia (LPH), Matthew L Goodwin, L Bruce Gladden, and Maarten W N Nijsten

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Limb lengthening in the treatment of posteromedial bowing of the tibia, J Eric Gordon, Perry L Schoenecker, Thomas R Lewis, and Mark L Miller

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Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration, Maud Gratuze, Cheryl Eg Leyns, Andrew D Sauerbeck, Marie-Kim St-Pierre, Monica Xiong, Nayeon Kim, Javier Remolina Serrano, Marie-Ève Tremblay, Terrance T Kummer, Marco Colonna, Jason D Ulrich, and David M Holtzman

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Epidemiological evidence for a hereditary contribution to myasthenia gravis: A retrospective cohort study of patients from North America, Joshua D Green, Julaine Florence, Alan Pestronk, Charlie Wulf, and et al

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Cell type-specific In vitro gene expression profiling of stem cell-derived neural models, James A Gregory, Celeste M Karch, and et al

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Phase Ib/II study combining tosedostat with capecitabine in patients with advanced pancreatic adenocarcinoma, Patrick Grierson, Andrea Teague, Rama Suresh, Kian-Huat Lim, Manik Amin, Katrina Pedersen, Benjamin Tan, Jesse Huffman, Nick Boice, Lingling Du, Jingxia Liu, A. Craig Lockhart, and Andrea Wang-Gillam

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REV-ERB agonism improves liver pathology in a mouse model of NASH, Kristine Griffett, Gonzalo Bedia-Diaz, Bahaa Elgendy, and Thomas P. Burris

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REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis, Percy Griffin, Patrick W. Sheehan, Julie M. Dimitry, Chun Guo, Michael F. Kanan, Jiyeon Lee, Jinsong Zhang, and Erik S. Musiek

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Damage to the shortest structural paths between brain regions is associated with disruptions of resting-state functional connectivity after stroke, Joseph C Griffis, Nicholas V Metcalf, Maurizio Corbetta, and Gordon L Shulman

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Detection of a somatic GREB1-NCOA1 gene fusion in a uterine tumor resembling ovarian sex cord tumor (UTROSCT), Whitney R Grither, Brendan C Dickson, Katherine C Fuh, and Ian S Hagemann

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Treatment patterns and blood counts in patients with polycythemia vera treated with hydroxyurea in the United States: An analysis from the REVEAL study, Michael R Grunwald, David J Kuter, Ivy Altomare, John M Burke, Aaron T Gerds, Mark A Walshauser, Michael R Savona, Brady Stein, Stephen T Oh, Philomena Colucci, Shreekant Parasuraman, Dilan Paranagama, and Ruben Mesa

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Enhanced recovery with paravertebral and transversus abdominis plane blocks in microvascular breast reconstruction, Ryan Guffey, Grace Keane, Austin Y. Ha, Rajiv Parikh, Elizabeth Odom, Li Zhang, and Terence M. Myckatyn

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RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation, Jordina Guillén-Boixet, Alex S. Holehouse, Rohit V. Pappu, and et al.

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The endosymbiont Wolbachia rebounds following antibiotic treatment, Emma L. Gunderson, Young-Jun Choi, Makedonka Mitreva, and et al.

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CD56 regulates human NK cell cytotoxicity through Pyk2, Justin T. Gunesch, Amera L. Dixon, Tasneem A.M. Ebrahim, Melissa M. Berrien-Elliott, Swetha Tatineni, Tejas Kumar, Everardo Hegewisch-Solloa, Todd A. Fehniger, and Emily M. Mace

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Time-series cardiovascular risk factors and receipt of screening for breast, cervical, and colon cancer: The Guideline Advantage, Aixia Guo, Bettina F. Drake, Yosef M. Khan, James R. Langabeer II, and Randi E. Foraker

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Coronary heart disease and mortality following a breast cancer diagnosis, Aixia Guo, Kathleen W Zhang, Kristi Reynolds, and Randi E Foraker

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Site-specific siderocalin binding to ferric and ferric-free enterobactin as revealed by mass spectrometry, Chunyang Guo, Lindsey K Steinberg, Ming Cheng, Jong Hee Song, Jeffrey P Henderson, and Michael L Gross

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Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth, Xiaofan Guo, Yuan Pan, Min Xiong, Shilpa Sanapala, Corina Anastasaki, Olivia Cobb, Sonika Dahiya, and David H. Gutmann

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Orsay virus CP-δ adopts a novel β-bracelet structural fold and incorporates into virions as a head fiber, Yusong R. Guo, Yanlin Fan, Ying Zhou, Miao Jin, Jim L. Zhang, Hongbing Jiang, Matthew V. Holt, Tao Wang, Nicolas L. Young, David Wang, Weiwei Zhong, and Yizhi J. Tao

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Proteomic resistance biomarkers for PI3K inhibitor in triple negative breast cancer patient-derived xenograft models, Zhanfang Guo, Tina Primeau, Jingqin Luo, Cynthia Zhang, Hua Sun, Jeremy Hoog, Feng Gao, Shixia Huang, Dean P Edwards, Sherri R Davies, Rebecca Aft, Li Ding, Matthew J Ellis, Shunqiang Li, and Cynthia X Ma

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Motile Onchocerca volvulus microfilariae in the anterior chamber of the eye, Michael E Gyasi, Augustine R Hong, and Gary J Weil

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Intracranial glioma xenograft model rapidly reestablishes blood–brain barrier integrity for longitudinal imaging of tumor progression using fluorescence molecular tomography and contrast agents, LeMoyne Habimana-Griffin, Dezhuang Ye, Julia Carpenter, Julie Prior, Gail Sudlow, Lynne Marsala, Matthew Mixdorf, Joshua B. Rubin, Hong Chen, and Samuel Achilefu

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Staged laser interstitial thermal therapy (LITT) treatments to left Insular low-grade glioma, Daniel M. Hafez, Caroline Liekweg, and Eric C. Leuthardt

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Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo, Pengfei Hai, Yuan Qu, Yang Li, Liren Zhu, Leonid Shmuylovich, Lynn A. Cornelius, and Lihong V. Wang

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A patient-centred, comprehensive model for the care for heart failure: The 360° heart failure centre, Ilia G Halatchev, Jay R McDonald, and Wen-Chin Wu

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Functional profiling of FSH and estradiol in ovarian granulosa cell tumors, Ulla-Maija Haltia, Marjut Pihlajoki, Noora Andersson, Lotta Mäkinen, Johanna Tapper, Alejandra Cervera, Hugo M. Horlings, Ursula Turpeinen, Mikko Anttonen, Ralf Bützow, Leila Unkila-Kallio, Olli Carpén, David B. Wilson, Markku Heikinheimo, and Anniina Färkkilä

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Outcomes of outpatient parenteral antimicrobial therapy with ceftriaxone for methicillin-susceptible Staphylococcus aureus bloodstream infections—a single-center observational study, Yasir Hamad, Lee Connor, Thomas C. Bailey, and Ige A. George

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Perspectives of patients on outpatient parenteral antimicrobial therapy: Experiences and adherence, Yasir Hamad, Sai Dodda, Allison Frank, Joe Beggs, Christopher Sleckman, Glen Kleinschmidt, Michael A. Lane, and Yvonne Burnett

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Mesh sprayer device with liquefied mesh delivery system: Proposed alternative for currently available meshes in hernia repair and supplement to abdominal closure, Alireza Hamidian Jahromi, David H Ballard, and F Dean Griffen

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The efficacy of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma exhibiting primary resistance to front-line targeted therapy or immunotherapy, Lana Hamieh, Rachel L Beck, Valerie H Le, and James J Hsieh

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Creatine kinase/α-crystallin interaction functions in cataract development, Paul D Hamilton, Stephanie L Bozeman, and Usha P Andley

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The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology, Benjamin L Handen, Anne M Fagan, Beau Ances, and et al

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Integration of mobile health into sickle cell disease care to increase hydroxyurea utilization: Protocol for an efficacy and implementation study, Jane S Hankins, Cecelia Calhoun, Ana Baumann, Lisa Klesges, and et al

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Ancestry specific associations of FTO gene variant and metabolic syndrome: A longitudinal ARIC study, Dale S. Hardy, Jane T. Garvin, Tesfaye B. Mersha, and Susan B. Racette

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Movement pattern training compared with standard strengthening and flexibility among patients with hip-related groin pain: Results of a pilot multicentre randomised clinical trial, Marcie Harris-Hayes, Karen Steger-May, Allyn M. Bove, Stefanie N. Foster, Michael J. Mueller, John C. Clohisy, and G. Kelley Fitzgerald

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WormBase: A modern Model Organism Information Resource, Todd W. Harris, Tim Schedl, and et al

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Tourette syndrome research highlights from 2019, Andreas Hartmann, Yulia Worbe, and Kevin J Black

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Perfect timing: Circadian rhythms, sleep, and immunity - an NIH workshop summary, Jeffrey A Haspel, Andrew E Gelman, Brian S Kim, and et al

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Implications of pneumonitis after chemoradiation and durvalumab for locally advanced non-small cell lung cancer, Comron Hassanzadeh, Timothy Sita, Rohan Savoor, Pamela P Samson, Jeffrey Bradley, Michelle Gentile, Michael Roach, Nisha Mohindra, Saiama Waqar, Timothy J Kruser, and Clifford Robinson

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Identifying barriers, facilitators, and implementation strategies for a faith-based physical activity program, Jessica Haughton, Michelle L Takemoto, Jennifer Schneider, Steven P Hooker, Borsika Rabin, Ross C Brownson, and Elva M Arredondo

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The glycoprotease CpaA secreted by medically relevant Acinetobacter species targets multiple O-linked host glycoproteins, M Florencia Haurat, Nichollas E Scott, Gisela Di Venanzio, Juvenal Lopez, Benjamin Pluvinage, Alisdair B Boraston, Michael J Ferracane, and Mario F Feldman

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Five years of ocrelizumab in relapsing multiple sclerosis: OPERA studies open-label extension, Stephen L Hauser, Robert T Naismith, and et al

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Considerations in preparative regimen selection to minimize rejection in pediatric hematopoietic transplantation in non-malignant diseases, Robert J Hayashi

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Redox systems biology: Harnessing the sentinels of the cysteine redoxome, Jason M. Held

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Management of healthcare personnel living with hepatitis B, hepatitis C, or human immunodeficiency virus in US healthcare institutions, David K Henderson, Louise-Marie Dembry, Costi D Sifri, Tara N Palmore, E Patchen Dellinger, Deborah S Yokoe, Christine Grady, Theo Heller, David Weber, Carlos Del Rio, Neil O Fishman, Valerie M Deloney, Tammy Lundstrom, and Hilary M Babcock

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Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome, Rachel L Henson, Eric Doran, Bradley T Christian, Benjamin L Handen, William E Klunk, Florence Lai, Joseph H Lee, H Diana Rosas, Nicole Schupf, Shahid H Zaman, Ira T Lott, and Anne M Fagan

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Diagnostic concordance of clinical diagnosis, tissue culture, and histopathology testing for skin and soft tissue infections: A single-center retrospective study, Christina M Herbosa, Trisha S Bhat, Yevgeniy R Semenov, Ilana S Rosman, and Amy C Musiek

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Targeting mitochondrial fusion and fission proteins for cardioprotection, Sauri Hernandez-Resendiz, Fabrice Prunier, Henrique Girao, Gerald Dorn, Derek J Hausenloy, and EU-CARDIOPROTECTION COST Action (CA16225)

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Maternal race/ethnicity and postpartum diabetes screening: A systematic review and meta-analysis, Cynthia J. Herrick, Ritika Puri, Rana Rahaman, Angela Hardi, Karyn Stewart, and Graham A. Colditz

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Characterization of glycan determinants that mediate recognition of the major Wuchereria bancrofti circulating antigen by diagnostic antibodies, Marla I Hertz, Amy Rush, Thomas B Nutman, Gary J Weil, Sasisekhar Bennuru, and Philip J Budge

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Imaging features of neonatal systemic juvenile xanthogranuloma: A case report and review of the literature, Siping He, Ke Jin, Xicheng Deng, Zhengzhen Zhou, Robert C McKinstry, and Yong Wang

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Performance of the lateral flow assay and the latex agglutination serum cryptococcal antigen test in cryptococcal disease in patients with and without HIV, Matthew A Hevey, Ige A George, Adriana M Rauseo, Lindsey Larson, William Powderly, and Andrej Spec

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DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods, Yu He, Hyo Sik Jang, Xiaoyun Xing, Daofeng Li, Michael J Vasek, Joseph D Dougherty, and Ting Wang

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Adaptation of arginine synthesis among uropathogenic branches of the Escherichia coli phylogeny reveals adjustment to the urinary tract habitat, Michael E Hibbing, Karen W Dodson, Vasilios Kalas, Swaine L Chen, and Scott J Hultgren

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Parental deployment and distress, and adolescent disordered eating in prevention-seeking military dependents, M K Higgins Neyland, Denise E Wilfley, and et al

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Aerococcus urinae isolated from women with lower urinary tract symptoms: In vitro aggregation and genome analysis, Evann E Hilt, Catherine Putonti, Krystal Thomas-White, Amanda L Lewis, Karen L Visick, Nicole M Gilbert, and Alan J Wolfe

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Evaluation of mavacamten in symptomatic patients with nonobstructive hypertrophic cardiomyopathy, Carolyn Y Ho, Richard G Bach, and et al.

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Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia: Primary results of the phase 4 BYOND study, Andreas Hochhaus, Camille Abboud, and et al

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Intentional and unintentional nonadherence to hydroxyurea among people with sickle cell disease: A qualitative study, Jason R. Hodges, Shannon M. Phillips, Sarah Norell, Chinonyelum Nwosu, Hamda Khan, Lingzi Luo, Sherif M. Badawy, Allison King, Paula Tanabe, Marsha Treadwell, Lucia Rojas Smith, Cecelia Calhoun, Jane S. Hankins, and Jerlym Porter

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Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses, Camaron R Hole, Woei C Lam, Rajendra Upadhya, and Jennifer K Lodge

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Heterotopic pregnancy diagnosed with point-of-care ultrasound in the emergency department: A case report, Ian J Holley and Sean P Stickles

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A molecular understanding of alphavirus entry, Autumn C. Holmes, Katherine Basore, Daved H. Fremont, and Michael S. Diamond

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Community health behaviors and geographic variation in early-onset colorectal cancer survival among women, Andreana N. Holowatyj, Marvin E. Langston, Yunan Han, Richard Viskochil, Jose Perea, Yin Cao, Charles R. Rogers, Christopher H. Lieu, and Justin X. Moore

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KRASG12C inhibition with sotorasib in advanced solid tumors, David S. Hong, Ramaswamy Govindan, and et al

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Fetal cortical plate segmentation using fully convolutional networks with multiple plane aggregation, Jinwoo Hong, Hyuk Jin Yun, Gilsoon Park, Seonggyu Kim, Cynthia T Laurentys, Leticia C Siqueira, Tomo Tarui, Caitlin K Rollins, Cynthia M Ortinau, P Ellen Grant, Jong-Min Lee, and Kiho Im

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An agonistic anti-CD137 antibody disrupts lymphoid follicle structure and T-cell-dependent antibody responses, Jun P Hong, Glennys V Reynoso, Prabhakar S Andhey, Amanda Swain, Jackson S Turner, Adrianus C M Boon, Florian Krammer, Ali H Ellebedy, Fabio Zanini, Maxim Artyomov, Heather D Hickman, and Michael S Diamond

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Safety and efficacy outcomes of the Xen45 Gel Stent use for refractory glaucoma: A surgery series from surgeon trainees at a tertiary teaching hospital, Karen Hong, John Lind, and Arsham Sheybani

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Neutrophil swarming delays the growth of clusters of pathogenic fungi, Alex Hopke, Allison Scherer, Samantha Kreuzburg, Michael S. Abers, Christa S. Zerbe, Mary C. Dinauer, Michael K. Mansour, and Daniel Irimia

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Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain, Kanta Horie, Nicolas R Barthélemy, Nipun Mallipeddi, Yan Li, Erin E Franklin, Richard J Perrin, Randall J Bateman, and Chihiro Sato

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Efficient generation and transcriptomic profiling of human iPSC-derived pulmonary neuroendocrine cells, Pooja Hor, Vasu Punj, Ben A Calvert, Alessandra Castaldi, Alyssa J Miller, Gianni Carraro, Barry R Stripp, Steven L Brody, Jason R Spence, Justin K Ichida, Amy L Ryan Firth, and Zea Borok

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The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis, John Horton, Philip J Budge, Gary Weil, and et al

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Activating immunity to fight a foe — A new path, Richard S. Hotchkiss and Steven M. Opal

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Cellular diversity of the regenerating caudal fin, Yiran Hou, Hyung Joo Lee, Yujie Chen, Jiaxin Ge, Fujr Osman Ibrahim Osman, Anthony R McAdow, Mayssa H Mokalled, Stephen L Johnson, Guoyan Zhao, and Ting Wang

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Androgen-influenced polarization of activin A-producing macrophages accompanies post-pyelonephritic renal scarring, Teri N. Hreha, Christina A. Collins, Allyssa L. Daugherty, Jessie M. Griffith, Keith A. Hruska, and David A. Hunstad

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TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis, Teri N Hreha, Christina A Collins, Allyssa L Daugherty, Joy Twentyman, Nitin Paluri, and David A Hunstad

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Exploiting the circuit breaker cancer evolution model in human clear cell renal cell carcinoma, James J Hsieh and Emily H Cheng

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Immunomodulatory roles of polysaccharide capsules in the intestine, Samantha A Hsieh and Paul M Allen

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Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2, Simon Hsu, Anna A Pimenova, Kimberly Hayes, Juan A Villa, Matthew J Rosene, Madhavi Jere, Alison M Goate, and Celeste M Karch

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Full-range space-division multiplexing optical coherence tomography angiography, Yongyang Huang, Jason Jerwick, Guoyan Liu, and Chao Zhou

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The price of the ticket: Health costs of upward mobility among African Americans, Darrell Hudson, Tina Sacks, Katie Irani, and Antonia Asher

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Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages, Jennifer F Hughes, Colin Kremitzki, Catrina Fronick, Tina A Graves-Lindsay, Lucinda Fulton, Wesley C Warren, Richard K Wilson, and et al.

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Primary cilia control glucose homeostasis via islet paracrine interactions, Jing W. Hughes, Jung Hoon Cho, Hannah E. Conway, Michael R. DiGruccio, Xue Wen Ng, Henry F. Roseman, Damien Abreu, Fumihiko Urano, and David W. Piston

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Social jetlag and prostate cancer incidence in Alberta's Tomorrow Project: A prospective cohort study, Liang Hu, Andrew Harper, Emily Heer, Jessica McNeil, Chao Cao, Yikyung Park, Kevin Martell, Geoffrey Gotto, Grace Shen-Tu, Cheryl Peters, Darren Brenner, and Lin Yang