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Submissions from 2020

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Runx2 plays a central role in osteoarthritis development, Di Chen, Dongyeon J. Kim, Jie Shen, Zhen Zou, and Regis J. O'Keefe

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Radiolabeled 6-(2, 3-dichlorophenyl)-N4-methylpyrimidine-2, 4-diamine (TH287): A potential radiotracer for measuring and imaging MTH1, Huaping Chen, Sadia Afrin, Yingqiu Guo, Wenhua Chu, Tammie L S Benzinger, Buck E Rogers, Joel R Garbow, Joel S Perlmutter, Dong Zhou, and Jinbin Xu

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Mining reported adverse events induced by potential opioid-drug interactions, Jinzhao Chen, Gaoyu Wu, Andrew Michelson, Zachary Vesoulis, Jennifer Bogner, John D Corrigan, Philip R O Payne, and Fuhai Li

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The membrane-associated form of cyclin D1 enhances cellular invasion, Ke Chen, Xuanmao Jiao, Anthony Ashton, Agnese Di Rocco, Timothy G. Pestell, Yunguang Sun, Jun Zhao, Mathew C. Casimiro, Zhiping Li, Michael P. Lisanti, Peter A. McCue, Duanwen Shen, Samuel Achilefu, Hallgeir Rui, and Richard G. Pestell

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Endogenous cyclin D1 promotes the rate of onset and magnitude of mitogenic signaling via Akt1 Ser473 phosphorylation, Ke Chen, Xuanmao Jiao, Agnese Di Rocco, Duanwen Shen, Shaohua Xu, Adam Ertel, Zuoren Yu, Gabriele Di Sante, Min Wang, Zhiping Li, Timothy G Pestell, Mathew C Casimiro, Emmanuel Skordalakes, Samuel Achilefu, and Richard G Pestell

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Postural directionality and head tremor in cervical dystonia, Qiyu Chen, Jeanne P Vu, Elizabeth Cisneros, Casey N Benadof, Zheng Zhang, Richard L Barbano, Christopher G Goetz, Joseph Jankovic, Hyder A Jinnah, Joel S Perlmutter, Mark I Appelbaum, Glenn T Stebbins, Cynthia L Comella, and David A Peterson

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Duodenal microbiota in stunted undernourished children with enteropathy, Robert Y Chen, Vanderlene L Kung, Matthew C Hibberd, Janaki Guruge, Blanda Di Luccia, Kazi Ahsan, Elizabeth Kennedy, Jesus Santiago-Borges, Michael J Barratt, Jeffrey I Gordon, and et al

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A spinal neural circuitry for converting touch to itch sensation, Sihan Chen, Xiao-Fei Gao, Yuxi Zhou, Ben-Long Liu, Xian-Yu Liu, Yufen Zhang, Devin M. Barry, Kun Liu, Yingfu Jiao, Rita Bardoni, Weifeng Yu, and Zhou-Feng Chen

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Robust principal component analysis for accurate outlier sample detection in RNA-Seq data, Xiaoying Chen, Bo Zhang, Ting Wang, Azad Bonni, and Guoyan Zhao

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A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: The Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC), Randall Chesnut, Michael Diringer, and et al

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Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle, Brendan Chestnut, Satish Casie Chetty, Andrew L. Koenig, and Saulius Sumanas

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Clinical controversies in anticoagulation monitoring and antithrombin supplementation for ECMO, Meghan M Chlebowski, Sirine Baltagi, Mel Carlson, Jerrold H Levy, and Philip C Spinella

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Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration, Yeon Sik Choi, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, and et al.

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Comparison of single-channel EEG, actigraphy, and sleep diary in cognitively normal and mildly impaired older adults, Chris A Chou, Cristina D Toedebusch, Tiara Redrick, David Freund, Jennifer S McLeland, John C Morris, David M Holtzman, and Brendan P Lucey

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LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target, Mayur Choudhary, Ebraheim N Ismail, Pei-Li Yao, Faryan Tayyari, Roxana A Radu, Steven Nusinowitz, Michael E Boulton, Rajendra S Apte, Jeffrey W Ruberti, James T Handa, Peter Tontonoz, and Goldis Malek

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Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility, Christine Chrissian, Emma Comacho, Man Shun Fu, Rafael Prados-Rosales, Subhasish Chatterjee, Radames J.B. Cordero, Jennifer K. Lodge, Arturo Casadevall, and Ruth E. Stark

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Mechanisms underlying familial aggregation of exceptional health and survival: A three-generation cohort study, Kaare Christensen, Mary K Wojczynski, Jacob K Pedersen, Lisbeth A Larsen, Susanne Kløjgaard, Axel Skytthe, Matt McGue, James W Vaupel, and Michael A Province

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DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders, Diana L Christian, Dennis Y Wu, Jenna R Martin, J Russell Moore, Yiran R Liu, Adam W Clemens, Sabin A Nettles, Nicole M Kirkland, Thomas Papouin, Cheryl A Hill, David F Wozniak, Joseph D Dougherty, and Harrison W Gabel

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Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity, Vincenza Cifarelli, Scott C Beeman, Gordon I Smith, Jun Yoshino, Darya Morozov, Joseph W Beals, Brandon D Kayser, Jeramie D Watrous, Mohit Jain, Bruce W Patterson, and Samuel Klein

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TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis, Francesca Cignarella, Fabia Filipello, Bryan Bollman, Claudia Cantoni, Alberto Locca, Robert Mikesell, Melissa Manis, Adiljan Ibrahim, Li Deng, Bruno A Benitez, Carlos Cruchaga, Danilo Licastro, Kathie Mihindukulasuriya, Oscar Harari, Michael Buckland, David M Holtzman, Arnon Rosenthal, Tina Schwabe, Ilaria Tassi, and Laura Piccio

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Design and rationale of the HAPIN study: A multicountry randomized controlled trial to assess the effect of liquefied petroleum gas stove and continuous fuel distribution, Thomas Clasen, Victor G. Davila-Roman, and et al.

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Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship, Susan E Coffin, Stephanie Fritz, Jason Newland, and et al

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DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner, Patrick L. Collins, Caitlin Purman, Sofia I. Porter, Vincent Nganga, Ankita Saini, Katharina E. Hayer, Greer L. Gurewitz, Barry P. Sleckman, Jeffrey J. Bednarski, Craig H. Bassing, and Eugene M. Oltz

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Rate of surgery and baseline characteristics associated with surgery progression in young athletes with prearthritic hip disorders, Reid W Collis, Andrea B McCullough, Chris Ng, Heidi Prather, Graham A Colditz, John C Clohisy, and Abby L Cheng

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Upregulation of 5′‑terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor, Kyle A. Cottrell, Ryan C. Chiou, and Jason D. Weber

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Early diagnosis and intervention in cystic fibrosis: Imagining the unimaginable, Andrea M Coverstone and Thomas W Ferkol

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The intriguing interaction of Escherichia coli with the host environment and innovative strategies to interfere with colonization: A summary of the 2019 E. coli and the Mucosal Immune System Meeting, Eric Cox, Meryem Aloulou, James M Fleckenstein, Christina Schäffer, Åsa Sjöling, Stephanie Schüller, Kurt Hanevik, Bert Devriendt, Weiping Zhang, Ann-Mari Svennerholm, and Edward G Dudley

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Genome-wide association study of opioid cessation, Jiayi W Cox, Richard M Sherva, Kathryn L Lunetta, Emma C Johnson, Nicholas G Martin, Louisa Degenhardt, Arpana Agrawal, Elliot C Nelson, Henry R Kranzler, Joel Gelernter, and Lindsay A Farrer

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Roxadustat for CKD-related anemia in non-dialysis patients, Daniel W Coyne and et al.

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Sucroferric oxyhydroxide in maintenance hemodialysis: A retrospective, comparative cohort study, Daniel W Coyne, Linda H Ficociello, Vidhya Parameswaran, Melissa M Rosen, Claudy Mullon, Robert J Kossmann, and Stuart M Sprague

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Genetic architecture of circulating very-long-chain (C24:0 and C22:0) ceramide concentrations, Sharon Cresci, Ruibo Zhang, Qiong Yang, Meredith S Duncan, Vanessa Xanthakis, Xuntian Jiang, Ramachandran S Vasan, Jean E Schaffer, and Linda R Peterson

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2019 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Catheter Ablation of Ventricular Arrhythmias: Executive summary, Edmond M Cronin, Phillip Cuculich, and et al

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2019 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Catheter Ablation of Ventricular Arrhythmias, Edmond M Cronin, Phillip Cuculich, and et al.

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2019 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Catheter Ablation of Ventricular Arrhythmias: Executive summary, Edmond M Cronin, Phillip Cuculich, and et al.

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The prevalence and clinical implications of comorbid back pain in shoulder instability: A Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability cohort study, Kevin Cronin, Robert Brophy, Matthew Smith, Rick Wright, and et al

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Germline sequencing identifies rare variants in Finnish subjects with familial germ cell tumors, Erin L Crowgey, Tea Soini, Nidhi Shah, Satu-Liisa Pauniaho, Pekka Lahdenne, David B Wilson, Markku Heikinheimo, and Todd E Druley

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Enhancing the anti-tumour activity of 177Lu-DOTA-octreotate radionuclide therapy in somatostatin receptor-2 expressing tumour models by targeting PARP, Carleen Cullinane, Kelly Waldeck, Laura Kirby, Buck E. Rogers, Peter Eu, Richard W. Tothill, and Rodney J. Hicks

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Assessment of benefit of advanced inflammatory bowel disease training: Challenges and solutions, Kelly C Cushing, Tomer Adar, Matthew Ciorba, and Ashwin N Ananthakrishnan

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Delirium prevention and treatment in the emergency department (ED): A systematic review protocol, Elijah Blue Dahlstrom, Jin Ho Han, Heather Healy, Maura Kennedy, Glenn Arendts, Jacques Lee, Chris Carpenter, and Sangil Lee

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Pragmatic application of the RE-AIM framework to evaluate the implementation of tobacco cessation programs within NCI-Designated Cancer Centers, Heather D'Angelo, Alex T Ramsey, Li-Shiun Chen, and et al

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The clonal evolution of metastatic colorectal cancer, Ha X Dang, Bradley A Krasnick, Julie G Grossman, Matthew S Strand, Jin Zhang, Christopher A Miller, Robert S Fulton, S Peter Goedegebuure, Catrina C Fronick, Malachi Griffith, David E Larson, Brian D Goetz, Jason R Walker, William G Hawkins, Steven M Strasberg, Kian H Lim, Timothy J Ley, Christopher A Maher, Ryan C Fields, and et al

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Long non-coding RNA LCAL62 / LINC00261 is associated with lung adenocarcinoma prognosis, Ha X Dang, Nicole M White, Emily B Rozycki, Brooke M Felsheim, Mark A Watson, Ramaswamy Govindan, Jingqin Luo, and Christopher A Maher

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Mitigating disruptions, and scalability of radiation oncology physics work during the COVID-19 pandemic, Arash Darafsheh, Hossein Lavvafi, Reza Taleei, and Rao Khan

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A germline variant at 8q24 contributes to familial clustering of prostate cancer in men of African ancestry, Burcu F Darst, Adam S Kibel, Bettina F Drake, and et al.

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Interleukin-22 inhibits respiratory syncytial virus production by blocking virus-mediated subversion of cellular autophagy, Sudipta Das, Claudette St Croix, Misty Good, Jie Chen, Jinming Zhao, Sanmei Hu, Mark Ross, Michael M Myerburg, Joseph M Pilewski, John Williams, Sally E Wenzel, Jay K Kolls, Anuradha Ray, and Prabir Ray

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Exploring differences in the role of hospitalization on weight gain based on treatment type from randomized clinical trials for adolescent anorexia nervosa, Nandini Datta, Brittany E Matheson, Daniel Le Grange, Harry A Brandt, Blake Woodside, Katherine A Halmi, Denise E Wilfley, and James D Lock

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Evaluation of naturalistic driving behavior using in-vehicle monitoring technology in preclinical and early Alzheimer's disease, Jennifer D Davis, Ganesh M Babulal, George D Papandonatos, Erin M Burke, Christopher B Rosnick, Brian R Ott, and Catherine M Roe

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The road to recovery: A pilot study of driving behaviors following antibody-mediated encephalitis, Gregory S. Day, Ganesh M. Babulal, Ganesh Rajasekar, Sarah Stout, and Catherine M. Roe

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Deciphering the factors that influence participation in studies requiring serial lumbar punctures, Gregory S Day, Tracy Rappai, Sushila Sathyan, and John C Morris

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MED19 regulates adipogenesis and maintenance of white adipose tissue mass by mediating PPARγ-dependent gene expression, John M Dean, Anyuan He, Min Tan, Jun Wang, Dongliang Lu, Babak Razani, and Irfan J Lodhi

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American Society of Hematology 2020 guidelines for sickle cell disease: Prevention, diagnosis, and treatment of cerebrovascular disease in children and adults, M.R. DeBaun, L.C. Jordan, A.A. King, J. Schatz, E. Vichinsky, C.K. Fox, R.C. McKinstry, P. Telfer, M.A. Kraut, L. Daraz, F.J. Kirkham, and M.H. Murad

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Blood biomarkers for detection of brain injury in COVID-19 patients, Steven T. DeKosky, Lawrence Lewis, Stacey House, and et al.

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Medulloblastoma has a global impact on health related quality of life: Findings from an international cohort, Cynthia B de Medeiros, Josh Rubin, and et al

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Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance, Zengqin Deng, Grigory Maksaev, Angela M. Schlegel, Jingying Zhang, Michael Rau, James A. J. Fitzpatrick, Elizabeth S. Haswell, and Peng Yuan

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Neutrophil elastase facilitates tumor cell intravasation and early metastatic events, Elena Deryugina, Alexia Carré, Veronica Ardi, Tomoki Muramatsu, Jonas Schmidt, Christine Pham, and James P Quigley

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The effect of exposure to long working hours on stroke: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury, Alexis Descatha, Bradley A Evanoff, and et al

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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17, Aniruddha Deshpande, Ziyad Al-Aly, Local Burden of Disease WaSH Collaborators, and et al

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Prevalence and family-related factors associated with suicidal ideation, suicide attempts, and self-injury in children aged 9 to 10 years, Danielle C. DeVille, Diana Whalen, Florence J. Breslin, Amanda S. Morris, Sahib S. Khalsa, Martin P. Paulus, and Deanna M. Barch

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Strategies to optimize ICU Liberation (A to F) Bundle performance in critically ill adults with coronavirus disease 2019, John W Devlin, Hollis R O'Neal Jr, Christopher Thomas, Mary Ann Barnes Daly, Joanna L Stollings, David R Janz, E Wesley Ely, and John C Lin

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Alcohol drinking and head and neck cancer risk: The joint effect of intensity and duration, Gioia Di Credico, Jose P Zevallos, and et al

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Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease, Aylin Dincer, Brian A Gordon, Sarah J Keefe, Shaney Flores, Nicole S McKay, Angela M Paulick, Rebecca L Feldman, Russ C Hornbeck, Beau M Ances, Nelly Joseph-Mathurin, Celeste M Karch, Eric M McDade, Richard J Perrin, Cyrus Raji, Qing Wang, Chengjie Xiong, John C Morris, Randall J Bateman, Tammie L S Benzinger, and et al

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Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction, Xunshan Ding, Rugmani Iyer, Christopher Novotny, Daniel Metzger, Heather H. Zhou, Gordon I. Smith, Mihoko Yoshino, Jun Yoshino, Samuel Klein, Gayathri Swaminath, Saswata Talukdar, and Yingjiang Zhou

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Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores, Hiroko H Dodge, John C Morris, and et al

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TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations, Paarth B Dodhiawala, Namrata Khurana, Daoxiang Zhang, Yi Cheng, Lin Li, Qing Wei, Kuljeet Seehra, Hongmei Jiang, Patrick M Grierson, Andrea Wang-Gillam, and Kian-Huat Lim

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Derivation of trophoblast stem cells from naïve human pluripotent stem cells, Chen Dong, Mariana Beltcheva, Paul Gontarz, Bo Zhang, Pooja Popli, Laura A. Fischer, Shafqat A Khan, Kyoung-Mi Park, Eun-Ja Yoon, Xiaoyun Xing, Ramakrishna Kommagani, Ting Wang, Lilianna Solnica-Krezel, and Thorold W. Theunissen

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Exome sequencing implicates impaired GABA signaling and neuronal ion transport in trigeminal neuralgia, Weilai Dong, Sheng Chih Jin, and et al

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FlyNet 2.0: Drosophila heart 3D (2D + time) segmentation in optical coherence microscopy images using a convolutional long short-term memory neural network, Zhao Dong, Jing Men, Zhiwen Yang, Jason Jerwick, Airong Li, Rudolph E Tanzi, and Chao Zhou

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Early socioemotional competence, psychopathology, and latent class profiles of reparative prosocial behaviors from preschool through early adolescence, Meghan Rose Donohue, Rebecca Tillman, and Joan Luby

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Therapies for tuberculosis and AIDS: Myeloid-derived suppressor cells in focus, Anca Dorhoi, Shabaana A Khader, and et al

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Serum urate lowering with allopurinol and kidney function in type 1 diabetes, Alessandro Doria, Janet B. McGill, and et al.

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Mitofusin 2 dysfunction and disease in mice and men, Gerald W Dorn II

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Proteogenomic characterization of endometrial carcinoma, Yongchao Dou, Daniel Cui Zhou, Alla Karpova, Yige Wu, Song Cao, Matthew A Wyczalkowski, Qingsong Gao, Sunantha Sethuraman, David Mutch, Katherine Fuh, Li Ding, and et al

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Evidence-based guidelines for managing patients with primary ER+ HER2− breast cancer deferred from surgery due to the COVID-19 pandemic, Mitch Dowsett, Cynthia X. Ma, and et al.

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Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases β-diversity in the gut microbiome of human immunodeficiency virus-exposed, uninfected infants, Alaric W D'Souza, Eshia Moodley-Govender, Bertram Berla, Tejas Kelkar, Bin Wang, Xiaoqing Sun, Brodie Daniels, Anna Coutsoudis, Indi Trehan, and Gautam Dantas

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Efficacy of bezlotoxumab in participants receiving metronidazole, vancomycin, or fidaxomicin for treatment of Clostridioides (Clostridium) difficile infection, Erik R. Dubberke, Dale N. Gerding, Ciarán P. Kelly, Kevin W. Garey, Galia Rahav, Audrey Mosley, Robert Tipping, and Mary Beth Dorr

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Assessing clinical research coordinator knowledge of good clinical practice: An evaluation of the state of the art and a test validation study, James M DuBois, Jessica T Mozersky, Alison L Antes, Kari Baldwin, and Michelle Jenkerson

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The relation between personality and biomarkers in sensitivity and conversion to Alzheimer-type dementia, Janet M Duchek, Andrew J Aschenbrenner, Anne M Fagan, Tammie L S Benzinger, John C Morris, and David A Balota

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Genetic variants and functional pathways associated with resilience to Alzheimer's disease, Logan Dumitrescu, Carlos Cruchaga, and et al

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Formation of lung inducible bronchus associated lymphoid tissue is regulated by Mycobacterium tuberculosis expressed determinants, Micah D Dunlap, Oliver A Prince, Javier Rangel-Moreno, Kimberly A Thomas, Julia M Scordo, Jordi B Torrelles, Jeffery Cox, Adrie J C Steyn, Joaquín Zúñiga, Deepak Kaushal, and Shabaana A Khader

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A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry, Zhaohui Du, Graham A. Colditz, Mark A. Fiala, Ravi Vij, and et al.

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Direct cost of surgically treated adult traumatic brachial plexus injuries, Christopher J Dy, Nithya Lingampalli, Kate Peacock, Margaret A Olsen, Wilson Z Ray, and David M Brogan

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Potent, specific MEPicides for treatment of zoonotic staphylococci, Rachel L. Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T. Shah, Justin J. Miller, Andrew J. Jezewski, Marwa O. Mikati, Xu Wang, Robert C. Brothers, Kenneth M. Heidel, Damon M. Osbourn, Carey-Ann D. Burnham, Sophie Alvarez, Stephanie A. Fritz, Cynthia S. Dowd, Joseph M. Jez, and Audrey R. Odom John

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Brain function distinguishes female carriers and non-carriers of familial risk for autism, Adam T Eggebrecht, Ally Dworetsky, Zoë Hawks, Rebecca Coalson, Babatunde Adeyemo, Savannah Davis, Daniel Gray, Alana McMichael, Steven E Petersen, John N Constantino, and John R Pruett

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The current state of antifungal stewardship among pediatric antimicrobial stewardship programs, Lourdes Eguiguren, Jason G Newland, Matthew P Kronman, Adam L Hersh, Jeffrey S Gerber, Grace M Lee, and Hayden T Schwenk

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The effect of smoking during pregnancy on severity and directionality of externalizing and internalizing symptoms: A genetically informed approach, Mikael O Ekblad, Kristine Marceau, Emily Rolan, Rohan H C Palmer, Alexandre Todorov, Andrew C Heath, and Valerie S Knopik

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Long-term employment outcomes among female cancer survivors, Christine C Ekenga, Eunsun Kwon, BoRin Kim, and Sojung Park

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A prospective study of weight gain in women diagnosed with early-stage invasive breast cancer, ductal carcinoma in situ, and women without breast cancer, Christine C. Ekenga, Xiaoyan Wang, Maria Pérez, Mario Schootman, and Donna B. Jeffe

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Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis, Jennifer L. Elliott, Jenna E. Eschbach, Pratibha C. Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q. Lawson, Alan N. Engelman, Mamuka Kvaratskhelia, and Sebla B. Kutluay

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Going beyond integration: The emerging role of HIV-1 integrase in virion morphogenesis, Jennifer L Elliott and Sebla B Kutluay

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Predictors of worsening neuropathy and neuropathic pain after 12 years in people with HIV, Ronald J Ellis, Monica Diaz, Ned Sacktor, Christina Marra, Ann C Collier, David B Clifford, Nigel Calcutt, Jerel A Fields, Robert K Heaton, Scott L Letendre, and CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group

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Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects, Nirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena C Haage, Elizabeth C Wright-Jin, Alexander Schattenberg, Roxane M Papawassiliou, Helmut Kettenmann, Marcus Semtner, and David H Gutmann

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Metabolic and addiction indices in patients on opioid agonist medication-assisted treatment: A comparison of buprenorphine and methadone, Igor Elman, Margaret Howard, Jacob T. Borodovsky, David Mysels, David Rott, David Borsook, and Mark Albanese

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Chloroquine triggers cell death and inhibits PARPs in cell models of aggressive hepatoblastoma, Katja Eloranta, Stefano Cairo, Emmi Liljeström, Tea Soini, Antti Kyrönlahti, Jean-Gabriel Judde, David B Wilson, Markku Heikinheimo, and Marjut Pihlajoki

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CD46 and oncologic interactions: Friendly fire against cancer, Michelle Elvington, M Kathryn Liszewski, and John P Atkinson

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The genetic architecture of human brainstem structures and their involvement in common brain disorders, Torbjørn Elvsåshagen, Deanna M. Barch, and et al.

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Fenofibrate reduces the severity of neuroretinopathy in a type 2 model of diabetes without inducing peroxisome proliferator-activated receptor alpha-dependent retinal gene expression, Jennifer M Enright, Sheng Zhang, Christina Thebeau, Emily Siebert, Alexander Jin, Veda Gadiraju, Xiaodong Zhang, Shiming Chen, Clay F Semenkovich, and Rithwick Rajagopal

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Intramuscular delivery of replicon RNA encoding ZIKV-117 human monoclonal antibody protects against Zika virus infection, Jesse H. Erasmus, Jennifer Govero, Qing Tan, Lorellin A. Durnell, Michael S. Diamond, Larissa B. Thackray, and et al.

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Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation, Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C. Bucelli, Gregory F. Wu, Maxim N. Artyomov, Anne H. Cross, and Brian T. Edelson

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Nanotherapy delivery of c-myc inhibitor targets protumor macrophages and preserves antitumor macrophages in breast cancer, Alison K. Esser, Michael H. Ross, Francesca Fontana, Xinming Su, Ariel Gabay, Gregory C. Fox, Yalin Xu, Jingyu Xiang, Anne H. Schmieder, Xiaoxia Yang, Grace Cui, Michael Scott, Samuel Achilefu, Jay Chauhan, Steven Fletcher, Gregory M. Lanza, and Katherine N. Weilbaecher

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SV‑HotSpot: Detection and visualization of hotspots targeted by structural variants associated with gene expression, Abdallah M. Eteleeb, David A. Quigley, Shuang G. Zhao, Duy Pham, Rendong Yang, Scott M. Dehm, Jingqin Luo, Felix Y. Feng, Ha X. Dang, and Christopher A. Maher