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Submissions from 2019

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A mutation in Site-1 Protease is associated with a complex phenotype that includes episodic hyperCKemia and focal myoedema, George G. Schweitzer, Connie Gan, Robert C. Bucelli, Daniel Wegner, Robert E. Schmidt, Marwan Shinawi, Brian N. Finck, and Rita T. Brookheart

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Mitofusin 2 is essential for IP3-mediated SR/mitochondria metabolic feedback in ventricular myocytes, Lea K. Seidlmayer, Christine Mages, Annette Berbner, Petra Eder-Negrin, Paula Anahi Arias-Loza, Mathias Kaspar, Moshi Song, Gerald W. Dorn II, Michael Kohlhaas, Stefan Frantz, Christoph Maack, Brenda Gerull, and Elena N. Dedkova

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Single-cell analysis reveals regional reprogramming during adaptation to massive small bowel resection in mice, Kristen M Seiler, Sarah E Waye, Wenjun Kong, Kenji Kamimoto, Adam Bajinting, William H Goo, Emily J Onufer, Cathleen Courtney, Jun Guo, Brad W Warner, and Samantha A Morris

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Patients with endometrial cancer continue to lack understanding of their risks for cancer, Subhjit Sekhon, L. Stewart Massad, Andrea R. Hagemann, Rebecca Dick, Andrea Leon, Abigail S. Zamorano, Premal H. Thaker, Carolyn K. McCourt, David G. Mutch, Matthew A. Powell, and Lindsay M. Kuroki

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The role of small or single-institution prospective studies in thoracic research, Tara R. Semenkovich, C. Corbin Frye, M. Shea Harrison, Melanie Subramanian, Benjamin D. Kozower, Bryam F. Meyers, and Varun Puri

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Blending insights from implementation science and the social sciences to mitigate inequities in screening for hereditary cancer syndromes, Laura Senier, Colleen M McBride, Alex T Ramsey, Vence L Bonham, and David A Chambers

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Clinical events after deferral of LAD revascularization following physiological coronary assessment, Sayan Sen, Jasvindar Singh, and et al

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Gut microbiota: From the forgotten organ to a potential key player in the pathology of Alzheimer's disease, Dong-Oh Seo and David M Holtzman

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Allogeneic transplantation in elderly patients ≥65 years with non-Hodgkin lymphoma: A time-trend analysis, Nirav N. Shah, Ravi Vij, and et al.

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Neoadjuvant cryotherapy improves dysphagia and may impact remission rates in advanced esophageal cancer, Tilak Shah, Vladimir Kushnir, Pritesh Mutha, Mankanchan Majhail, Bhaumik Patel, Matthew Schutzer, Drew Mogahanaki, George Smallfield, Milan Patel, and Alvin Zfass

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External dacryocystorhinostomy: A comparison of ultrasonic bone aspiration to high-speed drilling, Vikram A Shankar, Krishna Kalyam, and Steven M Couch

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Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice, Jie Shen, Cuicui Wang, Jun Ying, Taotao Xu, Audrey McAlinden, and Regis J. O'Keefe

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Bioresorbable optical sensor systems for monitoring of intracranial pressure and temperature, Jiho Shin, Zhonghe Liu, Wubin Bai, Yonghao Liu, Ying Yang, Yeguang Xue, Irawati Kandela, Maryam Pezhouh, Matthew R. MacEwan, Yonggang Huang, Wilson Z. Ray, Weidong Zhou, and John A. Rogers

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Are the intrinsically disordered linkers involved in SSB binding to accessory proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, and Timothy M. Lohman

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The association between handedness and clinicodemographic characteristics in people with multiple sclerosis: A brief report, Afsaneh Shirani, Anne H. Cross, Robert T. Naismith, and Multiple Sclerosis Partners Advancing Technology and Health Solutions Investigators#

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Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells, Keiro Shirotani, Yuma Hori, Ryohei Yoshizaki, Eri Higuchi, Marco Colonna, Takashi Saito, Shoko Hashimoto, Takashi Saito, Takaomi C. Saido, and Nobuhisa Iwata

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Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, and David M. Holtzman

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Seasonal variation in the incidence of malignant glaucoma after cataract surgery, Thomas S. Shute, Devesh K. Varma, Diamond Tam, Thomas Klein, Prima Moinul, Iqbal Ike K. Ahmed, and Arsham Sheybani

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The role of membrane excitability in pancreatic β-cell glucotoxicity, Zeenat A. Shyr, Zhiyu Wang, Nathaniel W. York, Colin G. Nichols, and Maria S. Remedi

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Gene expression analysis to detect disseminated tumor cells in the bone marrow of triple-negative breast cancer patients predicts metastatic relapse, Chidananda M Siddappa, Sreeraj G Pillai, Jackie Snider, Patsy Alldredge, Kathyrn Trinkaus, Mark A Watson, and Rebecca Aft

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Repetitive transcranial magnetic stimulation with resting-state network targeting for treatment-resistant depression in traumatic brain injury: A randomized, controlled, double-blinded pilot study, Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, and David L. Brody

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N-acyl-O-phosphocholineserines: Structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease, Rohini Sidhu, Yawo Mondjinou, Mingxing Qian, Fong-Fu Hsu, Dennis J. Dietzen, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang, and et al.

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Intraocular oxygen and antioxidant status: New insights on the effect of vitrectomy and glaucoma pathogenesis, Carla J Siegfried and Ying-Bo Shui

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Developing and assessing the feasibility of a home-based preexposure prophylaxis monitoring and support program, Aaron J Siegler, Kenneth H Mayer, Albert Y Liu, Rupa R Patel, Lauren M Ahlschlager, Colleen S Kraft, Rossi Fish, Sarah E Wiatrek, and Patrick S Sullivan

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Bimodal release ondansetron for acute gastroenteritis among adolescents and adults: A randomized clinical trial, Robert A. Silverman, Stacey L. House, Andrew C. Meltzer, Barry Hahn, Luis M. Lovato, Jahn Avarello, Joseph B. Miller, Ira N. Kalfus, Reza Fathi, Gilead Raday, Terry F. Plasse, and Eric C. Yan

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Congenital aortic valve stenosis, Gautam K Singh

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Communication interventions in adult and pediatric oncology: A scoping review and analysis of behavioral targets, Bryan A. Sisk, Ginny L. Schulz, Jennifer W. Mack, Lauren Yaeger, and James DuBois

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68Ga-Galmydar: A PET imaging tracer for noninvasive detection of doxorubicin-induced cardiotoxicity, Jothilingam Sivapackiam, Shivesh Kabra, Sylvia Speidel, Monica Sharma, Richard Laforest, Amber Salter, Michael P. Rettig, and Vijay Sharma

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Immune globulin subcutaneous, human - klhw 20% for primary humoral immunodeficiency: An open-label, Phase III study, John W Sleasman, William R Lumry, Iftikhar Hussain, H James Wedner, James B Harris, Kecia L Courtney, Elsa Mondou, Jiang Lin, and Mark R Stein

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Metabolically healthy obesity: Facts and fantasies, Gordon I Smith, Bettina Mittendorfer, and Samuel Klein

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Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice, Kate Smith-Jackson, Yi Yang, Harriet Denton, Isabel Y. Pappworth, Katie Cooke, Paul N. Barlow, John P. Atkinson, M. K. Liszewski, Matthew C. Pickering, David Kavanagh, H. T. Cook, and Kevin J. Marchbank

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Comparison of best versus worst clinical outcomes for adult cervical deformity surgery, Justin S Smith, Michael Kelly, Munish Gupta, and et al.

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Syndemic effects of HIV risk behaviours: Results from the NHANES study, L Smith, C Cao, X Zong, D T McDermott, S Stefanac, S Haider, S E Jackson, N Veronese, G F López-Sánchez, A Koyanagi, L Yang, and I Grabovac

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Levels and patterns of self-reported and objectively-measured free-living physical activity among prostate cancer survivors: A prospective cohort study, Lee Smith, Jung Ae Lee, Junbae Mun, Ratna Pakpahan, Kellie R Imm, Sonya Izadi, Adam S Kibel, Graham A Colditz, Robert L Grubb III, Kathleen Y Wolin, Siobhan Sutcliffe, and Lin Yang

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Route of administration for antibiotics with high oral bioavailability, Michael J. Smith, Cary Thurm, Samir S. Shah, Sameer J. Patel, Matthew P. Kronman, Jeffrey S. Gerber, Joshua D. Courter, Brian R. Lee, Jason G. Newland, and Adam L. Hersh

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Uterine natural killer cells, Dorothy K. Sojka, Liping Yang, and Wayne M. Yokoyama

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A protocol for the systematic review and meta-analysis of studies in which cannabinoids were tested for antinociceptive effects in animal models of pathological or injury-related persistent pain, Nadia Soliman, Andrea G. Hohmann, Simon Haroutounian, Kimberley Wever, Andrew S.C. Rice, and David P. Finn

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Effect of a novel transition program on disability after stroke: A trial protocol, Emily Somerville, Marian Keglovits, Yan Yan, and Susan Stark

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RAG-mediated DNA breaks attenuate PU.1 activity in early B cells through activation of a SPIC-BCLAF1 complex, Deepti Soodgupta, Lynn S. White, Wei Yang, Rachel Johnston, Jared M. Andrews, Masako Kohyama, Kenneth M. Murphy, Nima Mosammaparast, Jacqueline E. Payton, and Jeffrey J. Bednarski

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Association of the infant gut microbiome with early childhood neurodevelopmental outcomes: An ancillary study to the VDAART randomized clinical trial, Joanne E. Sordillo, Susan Korrick, Nancy Laranjo, Vincent Carey, George M. Weinstock, Diane R. Gold, George O'Connor, Megan Sandel, Leonard B. Bacharier, Avraham Beigelman, Robert Zeiger, Augusto A. Litonjua, and Scott T. Weiss

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AMIGO2 scales dendrite arbors in the retina, Florentina Soto, Nai-Wen Tien, Anurag Goel, Lei Zhao, Philip A. Ruzycki, and Daniel Kerschensteiner

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Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer, Alexandra A. Soukup, Ye Zheng, Charu Mahta, Jun Wu, Peng Liu, Miao Cao, Inga Hofmann, Yun Zhou, Jing Zhang, Kirby D. Johnson, Kyunghee Choi, Sunduz Keles, and Emery H. Bresnick

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Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes, Melanie A. Sparks, Saurabh P. Singh, Peter M. Burgers, and Roberto Galletto

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MRI radiomic features are independently associated with overall survival in soft tissue sarcoma, Matthew B. Spraker, Landon S. Wootton, Daniel S. Hippe, Kevin C. Ball, Jan C. Peeken, Meghan W. Macomber, Tobias R. Chapman, Michael N. Hoff, Edward Y. Kim, Seth M. Pollack, Stephanie E. Combs, and Matthew J. Nyflot

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Technological interventions for medication adherence in adult mental health and substance use disorders: A systematic review, Jackson M. Steinkamp, Nathaniel Goldblatt, Jacob T. Borodovsky, Amy LaVertu, Ian M. Kronish, Lisa A. Marsch, and Zev Schuman-Olivier

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Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9, Calvin J. Stephens, Elvin J. Lauron, Elena Kashentseva, Zhi Hong Lu, Wayne M. Yokoyama, and David T. Curiel

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Genetic architecture of human plasma lipidome and its link to cardiovascular disease, Nathan O. Stitziel and et al.

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Coronary artery disease risk and lipidomic profiles are similar in hyperlipidemias with family history and population-ascertained hyperlipidemias, Nathan O. Stitziel and et al

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Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission, Keith Stockerl-Goldstein and et al.

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Pancreatic stone protein/ regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells, Stephen Stone, Damien Abreu, Jana Mahadevan, Rie Asada, Kelly Kries, Rolf Graf, Bess A. Marshall, Tamara Hershey, and Fumihiko Urano

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Impaired hippocampal development and outcomes in very preterm infants with perinatal brain injury, Jennifer M. Strahle, Regina L. Triplett, Dimitrios Alexopoulos, Tara A. Smyser, Cynthia E. Rogers, David D. Limbrick Jr., and Christopher D. Smyser

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Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles, Matthew S. Strand, Bradley A. Krasnick, Hua Pan, Xiuli Zhang, Ye Bi, Candace Brooks, Christopher Wetzel, Narendra Sankpal, Timothy Fleming, S Peter Goedegebuure, David G. DeNardo, William E. Gillanders, William G. Hawkins, Samuel A. Wickline, and Ryan C. Fields

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Implementation of the Healthy Workplace Participatory Program in a retail setting: A feasibility study and framework for evaluation, Jaime R. Strickland, Anna M. Kinghorn, Bradley A. Evanoff, and Ann M. Dale

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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology, Marc Suarez-Calvet, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, and et al

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Comparison of opioid prescribing by dentists in the United States and England, Katie J. Suda, Michael J. Durkin, Gregory S. Calip, Walid F. Gellad, Hajwa Kim, Peter B. Lockhart, Susan A. Rowan, and Martin H. Thornhill

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Virus-induced cochlear inflammation in newborn mice alters auditory function, Cathy Yea Won Sung, Maria C. Seleme, Shelby Payne, Stipan Jonjic, Keiko Hirose, and William Britt

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity, Yun Ju Sung, Karen Schwander, Lisa de las Fuentes, Chi Charles Gu, Dabeeru C. Rao, Mary F. Feitosa, Aldi T. Kraja, and Michael A. Province

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Mild chronic perturbation of inhibition severely alters hippocampal function, Min-Yu Sun, Luke Ziolkowski, Peter Lambert, Hong-Jin Shu, Micah Keiser, Nicholas Rensing, Natasha Warikoo, Monika Martinek, Carson Platnick, Ann Benz, John Bracamontes, Gustav Akk, Joe Henry Steinbach, Charles F. Zorumski, Michael Wong, and Steven Mennerick

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Diffusion basis spectrum imaging provides insights into MS pathology, Peng Sun, Ajit George, Dana C. Perantie, Kathryn Trinkaus, Zezhong Ye, Robert T. Naismith, Sheng-Kwei Song, and Anne H. Cross

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Association of fried food consumption with all cause, cardiovascular, and cancer mortality: Prospective cohort study, Yangbo Sun, Buyun Liu, Linda G. Snetselaar, Jennifer G. Robinson, Robert B. Wallace, Lindsay L. Peterson, and Wei Bao

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Comparison of the impact of annual and semiannual mass drug administration on lymphatic filariasis prevalence in Flores Island, Indonesia, Taniawati Supali, Yenny Djuardi, Adriani Lomiga, Sovie N. Linda, Elisa Iskandar, Charles W. Goss, John P. Miller, Gary J. Weil, and Peter U. Fischer

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The spectrum of bladder health: The relationship between lower urinary tract symptoms and interference with activities, Siobhan Sutcliffe, Tamara Bavendam, Charles Cain, Neill Epperson, Colleen M. Fitzgerald, Sheila Gahagan, Alayne D. Markland, David A. Shoham, Ariana L. Smith, Mary K. Townsend, Kyle Rudser, and Prevention of Lower Urinary Tract Symptoms Research Consortium

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AAV-mediated TAZ gene replacement restores mitochondrial and cardioskeletal function in Barth syndrome, Silveli Suzuki-Hatano, Madhurima Saha, Skylar A. Rizzo, Rachael L. Witko, Bennett J. Gosiker, Manashwi Ramanathan, Meghan S. Soustek, Michael D. Jones, Peter B. Kang, Barry J. Byrne, W. Todd Cade, and Christina A. Pacak

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AAV9-TAZ gene replacement ameliorates cardiac TMT proteomic profiles in a mouse model of Barth syndrome, Silveli Suzuki-Hatano, Madhurima Saha, Meghan S. Soustek, Peter B. Kang, Barry J. Byrne, W. Todd Cade, and Christina A. Pacak

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Increased mtDNA abundance and improved function in human Barth syndrome patient fibroblasts following AAV-TAZ gene delivery, Silveli Suzuki-Hatano, Mughil Sriramvenugopal, Manash Ramanathan, Meghan Soustek, Barry J. Byrne, W. T. Cade, Peter B. Kang, and Christina A. Pacak

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Disseminating and implementing a lifestyle-based healthy weight program for mothers in a national organization: A study protocol for a cluster randomized trial, Rachel G Tabak, Cynthia D Schwarz, Allison Kemner, Kenneth B Schechtman, Karen Steger-May, Veronda Byrth, and Debra Haire-Joshu

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Reaching the end of the line: Urinary tract infections, Kevin O Tamadonfar, Natalie S Omattage, Caitlin N Spaulding, and Scott J Hultgren

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TREM1/3 deficiency impairs tissue repair after acute kidney injury and mitochondrial metabolic flexibility in tubular epithelial cells, Alessandra Tammaro, Angelique M.L Scantlebery, Elena Rampanelli, Cristiana Borrelli, Nike Claessen, Loes M. Butter, Alessandra Soriani, Marco Colonna, Jaklien C. Leemans, Mark C. Dessing, and Sandrine Florquin

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Ultrasound visualization of radial nerve excursion during acupuncture, Chi-Tsai Tang and Abby L. Cheng

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DC-SCRIPT deficiency delays mouse mammary gland development and branching morphogenesis, Chunling Tang, Renske J E van den Bijgaart, Maaike W G Looman, Nina Tel-Karthaus, Annemarie M A de Graaf, Susan Gilfillan, Marco Colonna, Marleen Ansems, and Gosse J Adema

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3D printing custom bioactive and absorbable surgical screws, pins, and bone plates for localized drug delivery, Karthik Tappa, Udayabhanu Jammalamadaka, Jeffery A. Weisman, David H. Ballard, Dallas D. Wolford, Cecilia Pascual-Garrido, Larry M. Wolford, Pamela K. Woodard, and David K. Mills

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Performance of commercial tests for molecular detection of Shiga toxin-producing Escherichia coli (STEC): A systematic review and meta-analysis protocol, Gillian A.M. Tarr, Chu Yang Lin, Diane Lorezetti, Linda Chui, Phillip I. Tarr, Lisa Hartling, Ben Vandermeer, and Stephen B. Freedman

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Contribution and interaction of Shiga toxin genes to Escherichia coli O157:H7 virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, and Linda Chui

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RAB10: An Alzheimer’s disease resilience locus and potential drug target, Justina P. Tavana, Matthew Rosene, Nick O. Jensen, Perry G. Ridge, John S.K Kauwe, and Celeste M. Karch

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Clinical performance of the BioPlex 2200 Syphilis Total & RPR assay at a tertiary medical center with a high rate of syphilis, Merih T. Tesfazghi, Neil W. Anderson, Ann M. Gronowski, and Melanie L. Yarbrough

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Mitochondrial quality control in aging and heart failure: Influence of ketone bodies and mitofusin-stabilizing peptides, Phung N. Thai, Lea K. Seidlmayer, Charles Miller, Maura Ferrero, Gerald W. Dorn II, Saul Schaefer, Donald M. Bers, and Elena N. Dedkova

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Comparative genomics of antibiotic-resistant uropathogens implicates three routes for recurrence of urinary tract infections, Robert Thänert, Kimberly A Reske, Tiffany Hink, Meghan A Wallace, Bin Wang, Drew J Schwartz, Sondra Seiler, Candice Cass, Carey-Ann D. Burnham, Erik R Dubberke, Jennie H Kwon, and Gautam Dantas

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Validity and reliability of telephone administration of the patient-specific functional scale for the assessment of recovery from snakebite envenomation, Rebecca G. Theophanous, Michael E. Mullins, and et al.

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Advances in cardiovascular disease lipid research can provide novel insights into mycobacterial pathogenesis, Shyamala Thirunavukkarasu and Shabaana A. Khader

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CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans, Brian J. Thomas, Ira E. Wright, Wendy Y. Y. Chou, Marco Moreno, Zachary Dawson, Airelle Homayouni, Huiyan Huang, Hyori Kim, Hanna Jia, Justin R. Buland, Jennifer A. Wambach, F. Sessions Cole, Stephen C. Pak, Gary A. Silverman, and Cliff J. Luke

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The structure of cognition in 9 and 10 year-old children and associations with problem behaviors: Findings from the ABCD study's baseline neurocognitive battery, Wesley K Thompson, Deanna M Barch, James M Bjork, Raul Gonzalez, Bonnie J Nagel, Sara Jo Nixon, and Monica Luciana

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Palatine tonsillar metastasis of lung adenocarcinoma: An unusual immunohistochemical phenotype and a potential diagnostic pitfall, Ying Tian, Yunan Han, Jiang Du, Yao Zhang, Nan Liu, Xin Du, and Bo Li

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Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity, Scott A. Tiscione, Oscar Vivas, Kenneth S. Ginsburg, Donald M. Bers, Daniel S. Ory, Luis F. Santana, Rose E. Dixon, and Eamonn J. Dickson

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Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia, Elizabeth M. Todd, Rashmi Ramani, Taylor P. Szasz, and S. Celeste Morley

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Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel, Ailing Tong, John T. Petroff II, Fong-Fu Hsu, Philipp A.M. Schmidpeter, Crina M. Nimigean, Liam Sharp, Grace Brannigan, and Wayland W.L. Cheng

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Clinical variables and genetic risk factors associated with the acute outcome of ischemic stroke: A systematic review, Nuria P. Torres-Aguila, Laura Ibañez, Laura Heitsch, Carlos Cruchaga, Jin-Moo Lee, and et al.

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Relationship between device acceptance and patient-reported outcomes in left ventricular assist device (LVAD) recipients, Crispino Tosto, Luigi Adamo, Heidi Craddock, Maria Di Blasi, Rosario Girgenti, Francesco Clemenza, Robert M. Carney, and Gregory Ewald

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Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics, Rahul Tyagi, Mostafa A. Elfawal, Scott A. Wildman, Jon Helander, Christina A. Bulman, Judy Sakanari, Bruce A. Rosa, Paul J. Brindley, James W. Janetka, Raffi V. Aroian, and Makedonka Mitreva

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The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone–substrate interaction, Darya V. Urusova, Rachel L. Kinsella, Nichole D. Salinas, M. Florencia Haurat, Mario F. Feldman, and Niraj H. Tolia

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L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams, Kelli L. VanDussen, Naomi M. Sonnek, and Thaddeus S. Stappenbeck

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A phase II clinical study of 13-deoxy, 5-iminodoxorubicin (GPX-150) with metastatic and unresectable soft tissue sarcoma, Brian A. Van Tine, Mark Agulnik, Richard D. Olson, Gerald M. Walsh, Arthur Klausner, Nicole E. Frank, Todd T. Talley, and Mohammed M. Milhem

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Antibiotic stewardship teams and Clostridioides difficile practices in United States hospitals: A national survey in The Joint Commission antibiotic stewardship standard era, Valerie M Vaughn, M Todd Greene, David Ratz, Karen E Fowler, Sarah L Krein, Scott A Flanders, Erik R Dubberke, Sanjay Saint, and Payal K Patel

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Cluster analysis to define distinct clinical phenotypes among septic patients with bloodstream infections, Maria Cristina Vazquez Guilamet, Michael Bernauer, Scott T. Micek, and Marin H. Kollef

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Acquisition of dynamic function in human stem cell-derived β cells, Leonardo Velazco-Cruz, Jiwon Song, Kristina G. Maxwell, Madeleine M. Goedegebuure, Punn Augsornworawat, Nathaniel J. Hogrebe, and Jeffrey R. Millman

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Recommendations for the management of elevated intraocular pressure due to bleb fibrosis after XEN gel stent implantation, Vanessa Vera, Arsham Sheybani, Dan Lindfield, Ingeborg Stalmans, and Iqbal Ike K. Ahmed

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A short translational ramp determines the efficiency of protein synthesis, Manasvi Verma, Junhong Choi, Kyle A. Cottrell, Zeno Lavagnino, Erica N. Thomas, Slavica Pavlovic-Djuranovic, Pawel Szczesny, David W. Piston, Hani S. Zaher, Joseph D. Puglisi, and Sergej Djuranovic

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Novel mutation in TNPO3 causes congenital limb-girdle myopathy with slow progression, Anna Vihola, Johanna Palmio, Olof Danielsson, Sini Penttilä, Daniel Louiselle, Sara Pittman, Conrad Weihl, and Bjarne Udd

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Oral selinexor–dexamethasone for triple-class refractory multiple myeloma, Ravi Vij and et al.

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Niemann-Pick type C disease reveals a link between lysosomal cholesterol and PtdIns(4,5)P2 that regulates neuronal excitability, Oscar Vivas, Scott A. Tiscione, Rose E. Dixon, Daniel S. Ory, and Eamonn J. Dickson

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Recent advances in preventing and managing postoperative delirium [version 1; peer review: 2 approved], Phillip Vlisides and Michael Avidan