Submissions from 2015
Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits, Richard K. Wilson, Wesley Warren, and et al
WU-CRISPR: Characteristics of functional guide RNAs for the CRISPR/Cas9 system, Nathan Wong, Weijun Liu, and Xiaowei Wang
miRDB: An online resource for microRNA target prediction and functional annotations, Nathan Wong and Xiaowei Wang
Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru, Andrew Wu, Philip J. Budge, John Williams, Marie R. Griffin, Kathryn M. Edwards, Monika Johnson, Yuwei Zhu, Stella Hartinger, Hector Verastegui, Ana I. Gil, Claudio F. Lanata, and Carlos G. Grijalva
Evaluation of rigid registration methods for whole head imaging in diffuse optical tomography, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani
Fast and efficient image reconstruction for high density diffuse optical imaging of the human brain, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani
Development and evaluation of an enterovirus D68 real-time reverse transcriptase PCR assay, Todd N. Wylie, Kristine M. Wylie, Richard S. Buller, Maria Cannella, and Gregory A. Storch
Enhanced virome sequencing using targeted sequence capture, Todd N. Wylie, Kristine M. Wylie, Brandi N. Herter, and Gregory A. Storch
Neuronal-targeted TFEB accelerates lysosomal degradation of app, reducing Aβ generation and amyloid plaque pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan, and Jin-Moo Lee
Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment, Maorong Xie, Baoqin Xuan, Jiaoyu Shan, Deng Pan, Yamei Sun, Zhao Shan, Jinping Zhang, Dong Yu, Bin Li, and Zhlkang Qian
Circadian and light-driven regulation of rod dark adaptation, Yunlu Xue, Susan Q. Shen, Joseph C. Corbo, and Vladimir J. Kefalov
CRALBP supports the mammalian retinal visual cycle and cone vision, Yunlu Xue, Susan Q. Shen, Jonathan Jui, Alan C. Rupp, Leah C. Byrne, Samer Hattar, John G. Flannery, Joseph C. Corbo, and Vladimir J. Kefalov
Postmenopausal mammographic breast density and subsequent breast cancer risk according to selected tissue markers, Lusine Yaghjyan, Andreas Pettersson, Graham A. Colditz, Laura C. Collins, Stuart J. Schnitt, Andrew H. Beck, Bernard Rosner, Celine Vachon, and Rulla M. Tamimi
A comparison of two tests for filarial antigenemia in areas in Sri Lanka and Indonesia with low-level persistence of lymphatic filariasis following mass drug administration, Thishan C. Yahathugoda, Taniawati Supali, Ramakrishna U. Rao, Yenny Djuardi, Difa Stefani, Femmy Pical, Peter U. Fischer, Melanie M. Lloyd, Prasad H. Premaratne, Mirani V. Weerasooriya, and Gary J. Weil
Analysis of in vivo turnover of tau in a mouse model of tauopathy, Kaoru Yamada, Tirth K. Patel, Katja Hochgrafe, Thomas E. Mahan, Hong Jiang, Floy R. Stewart, Eva-Maria Mandelkow, and David M. Holtzman
Chronic optogenetic activation augments Aβ pathology in a mouse model of Alzheimer disease, Kaoru Yamamoto, Zen-ichi Tanei, Tadafumi Hashimoto, Tomoko Wakabayashi, Hiroyuki Okuno, Yasushi Naka, Ofer Yizher, Lief E. Fenno, Masashi Fukayama, Haruhiko Bito, John R. Cirrito, David M. Holtzman, Karl Deisseroth, and Takeshi Iwatsubo
Anti-tau antibody reduces insoluble tau and decreases brain atrophy, Kiran Yanamandra, Hong Jiang, Thomas E. Mahan, Susan E. Maloney, David F. Wozniak, Marc I. Diamond, and David M. Holtzman
Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation, Huimin Yan, Hui-fang Zhou, Ying Hu, and Christine T.N. Pham
Evaluating a train-the-trainer approach for improving capacity for evidence-based decision making in public health, Laura Yarber, Carol A. Brownson, Rebekah R. Jacob, Elizabeth A. Baker, Ellen Jones, Carsten Baumann, Anjali D. Deshpande, Kathleen N. Gillespie, Darcell P. Scharff, and Ross C. Brownson
Congenital acute myeloid leukemia with unique translocation t(11;19)(q23;p13.3), Chester K. Yarbrough, S. Kathleen Bandt, Kyle Hurth, Jennifer A. Wambach, Rakesh Rao, Shashikant Kulkarni, Francis V. White, John L. Frater, and Jeffrey R. Leonard
Impaired fas-fas ligand interactions result in greater recurrent herpetic stromal keratitis in mice, Xiao-Tang Yin, Tammie L. Keadle, Jessicah Hard, John Herndon, Chelsea R. Del Rosso, Thomas A. Ferguson, and Patrick M. Stuart
Fibroblast growth factor 9 regulation by MicroRNAs controls lung development and links DICER1 loss to the pathogenesis of Pleuropulmonary Blastoma, Yongjun Yin, Angela M. Castro, Marrit Hoekstra, Thomas J. Yan, Ajay C. Kanakamedala, Louis P. Dehner, D. Ashley Hill, and David M. Ornitz
Clostridium difficile infection among veterans health administration patients, Yinong Young-Xu, Jennifer L. Kuntz, Dale N. Gerding, Julia Neily, Peter Mills, Erik R. Dubberke, Margaret A. Olsen, Ciarán P. Kelly, and Cédric Mahé
Abnormal structural connectivity in the brain networks of children with hydrocephalus, Weihong Yuan, Scott K. Holland, Joshua S. Shimony, Mekibib Altaye, Francesco T. Mangano, David D. Limbrick, Blaise V. Jones, Tiffany Nash, Akila Rajagopal, Sarah Simpson, Dustin Ragan, and Robert C. McKinstry
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology, Jinsheng Yu, Paul F. Cliften, Twyla I. Juehne, Toni M. Sinnwell, Chris S. Sawyer, Mala Sharma, Andrew Lutz, Eric Tycksen, Mark R. Johnson, Matthew R. Minton, Elliott T. Klotz, Andrew E. Schriefer, Wei Yang, Michael E. Heinz, Seth D. Crosby, and Richard D. Head
ανβ3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment, Ruiying Zhang, Dipanjan Pan, Xin Cai, Xiaoxia Yang, Angana Senpan, John S. Allen, Gregory M. Lanza, and Lihong V. Wang
Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo, Weili Zhang, Kory J. Lavine, Slava Epelman, Sarah A. Evans, Carla J. Weinheimer, Philip M. Barger, and Douglas L. Mann
The DHX33 RNA helicase promotes mRNA translation initiation, Yandong Zhang, Jin You, Xingshun Wang, and Jason Weber
Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production, Yong Zhang, Michael Holtzman, and et al
Identification of candidate adherent-invasive E. coli signature transcripts by genomic/transcriptomic analysis, Yuanhao Zhang, Leahana Rowehl, Julia M. Krumsiek, Erika P. Omer, Nurmohammad Shaikh, Phillip I. Tarr, Erica Sodergren, George M. Weinstock, Edgar C. Boedeker, Xuejian Xiong, John Parkinson, Daniel N. Frank, Ellen Li, and Grace Gathungu
DNAM-1 controls NK cell activation via an ITT-like motif, Zhanguang Zhang, Ning Wu, Yan Lu, Dominique Davidson, Marco Colonna, and Andre Veillette
Use of diverging apertures to minimize the edge scatter in passive scattering proton therapy, Tianyu Zhao, Bin Cai, Baozhou Sun, Kevin Grantham, Sasa Mutic, and Eric Klein
Preclinical positron emission tomographic imaging of acute hyperoxia therapy of chronic hypoxia during pregnancy, Alexander Zheleznyak, Joel R. Garbow, MIchal Neeman, and Suzanne E. Lapi
Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates, Julie Y. Zhou, Megan Isaacson-Schmid, Elizabeth C. Utterson, Elizabeth M. Todd, Michelle McFarland, Janardan Sivapalan, Joan M. Niehoff, Carey-Ann D. Burnham, and S. Celeste Morley
Longitudinal analysis of the premature infant intestinal microbiome prior to necrotizing enterocolitis: A case-control study, Yanjiao Zhou, Gururaj Shan, Erica Sodergren, George Weinstock, W. Allen Walker, and Katherine E. Gregory
Treatment-resistant major depression: Rationale for NMDA receptors as targets and nitrous oxide as therapy, Charles F. Zorumski, Peter Nagele, Steven Mennerick, and Charles R. Conway
Modular design of the selectivity filter pore loop in a novel family of prokaryotic ‘inward rectifier’ (NirBac) channels, Lejla Zubcevic, Shizhen Wang, Vassiliy N. Bavro, Sun-Joo Lee, Colin G. Nichols, and Stephen J. Tucker
Evidence-based diabetes prevention and control programs and policies in local health departments, Melissa Zwald, Lindsay Elliott, Ross C. Brownson, and Mahree Skala
Submissions from 2014
Current clinical practice: differential management of uveal melanoma in the era of molecular tumor analyses, Thomas M. Aaberg Jr., Robert W. Cook, Kristen Oelschlager, Derek Maetzold, P. Kumar Rao, and John O. Mason III
Identification and characterization of alternative splicing in parasitic nematode transcriptomes, Sahar Abubucker, Samantha N. McNulty, Bruce A. Rosa, and Makedonka Mitreva
Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States, Jennifer M. Adams-Haduch, Ezenwa O. Onuoha, Tatiana Bogdanovich, Guo-Bao Tian, Jonas Marschall, Carl M. Urban, Brad J. Spellberg, Diane Rhee, Diane C. Halstead, Anthony W. Pasculle, and Yohei Doi
Revision total hip arthroplasty with retained acetabular component, Muyibat A. Adelani, Nathan A. Mall, Humaa Nyazee, John C. Clohisy, Robert L. Barrack, and Ryan M. Nunley
A prospective trial comparing FDG-PET/CT and CT to assess tumor response to cetuximab in patients with incurable squamous cell carcinoma of the head and neck, Douglas Adkins, Jessica Ley, Farrokh Dehdashti, Marilyn J. Siegel, Tanya M. Wildes, Loren Michel, Kathryn Trinkaus, and Barry A. Siegel
Perceived benefits and challenges of coordinated approaches to chronic disease prevention in state health departments, Peg Allen, Sonia Sequeria, Leslie Best, Ellen Jones, Elizabeth A. Baker, and Ross C. Brownson
Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection, David M. Alvarado, Ping Yang, Todd E. Druley, Michael Lovett, and Christina A. Gurnett
Allograft AlloDerm® tissue for laparoscopic transabdominal preperitoneal groin hernia repair: A case report, Bardia Amirlak, Jodi Gerdes, Varun Puri, and Robert J. Fitzgibbons
In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin, Usha P. Andley, James P. Malone, and R. Reid Townsend
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: Evidence for synthetic association in prostate cancer, Gerald Andriole and et al
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes, Ping An, Aldi Kraja, Michael A. Province, Ingrid B. Borecki, and et al.
Aligning objectives and assessment in responsible conduct of research instruction, Alison Antes and James M. DuBois
Intravenous immunoglobulin in BK virus nephropathy, Elizabeth I. Anyaegbu and Stanley P. Hmiel
A training programme to build cancer research capacity in low- and middle-income countries: Findings from Guatemala, Lauren D Arnold, Joaquin Barnoya, Eduardo N Gharzouzi, Peter Benson, and Graham A Colditz
Ultrasonography versus computed tomography for suspected nephrolithiasis, C. Aubin and R. T. Griffey
The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: Protocol for an international multicentre randomised controlled trial, Michael S. Avidan, Bradley A. Fritz, Hannah R. Maybrier, Maxwell R. Muench, Krisztina E. Escallier, Yulong Chen, Arbi Ben Abdallah, and et al
Motherhood, psychological risks, and resources in relation to alcohol use disorder: Are there differences between black and white women?, Sundari Balan, Gregory Widner, Hsing-Jung Chen, Darrell Hudson, Sarah Gehlert, and Rumi Kato Price
The role of resting state networks in focal neocortical seizures, S. Kathleen Bandt, David T. Bundy, Ammar H. Hawasli, Kareem W. Ayoub, Mohit Sharma, Carl D. Hacker, Mrinal Pahwa, and Eric C. Leuthardt
Conference Highlights of the 16th International Conference on Human Retrovirology: HTLV and Related Retroviruses, 26–30 June 2013, Montreal, Canada, Benoit Barbeau, John Hiscott, Ali Bazarbachi, Edgar Carvalho, Kathryn Jones, Fabiola Martin, Masao Matsuoka, Edward L. Murphy, Lee Ratner, William M. Switzer, and Toshiki Watanabe
Prevalence of cigarette advertising and other promotional strategies at the point of sale in St Louis, Missouri: Analysis by store type and distance from a school, Joaquin Barnoya, Graham Colditz, Sarah Moreland-Russell, Julianne Cyr, Doneisha Snider, and Mario Schootman
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma, Amy Barone, Rajarshi Sengupta, Nicole M. Warrington, Erin Smith, Patrick Y. Wen, Rolf A. Brekken, Barbara Romagnoli, Garry Douglas, Eric Chevalier, Michael P. Bauer, Klaus Dembowsky, David Piwnica-Worms, and Joshua B. Rubin
Red blood cell invasion by Plasmodium vivax: Structural basis for DBP engagement of DARC, Joseph D. Batchelor, Brian M. Malpede, Natalie S. Omattage, Gregory T. DeKoster, Katherine A. Henzler-Wildman, and Niraj H. Tolia
Tax inflicts DNA damage through activation of Nitric Oxide production, Hicham H. Baydoun and Lee Ratner
Prognostic significance of β-human chorionic gonadotropin and PAX8 expression in anaplastic thyroid carcinoma, Nils Becker, Rebecca D. Chernock, Brian Nussenbaum, and James S. Lewis Jr.
Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development, Michael S. Behnke, Tiange P. Zhang, Jitender P. Dubey, and L. David Sibley
Differential induction of TLR3-dependent innate immune signaling by closely related parasite species, Daniel P. Beiting, Lucia Peixoto, Natalia S. Akopyants, Stephen M. Beverley, E. John Wherry, David A. Christian, Christopher A. Hunter, Igor E. Brodsky, and David S. Roos
Neural activation associated with the cognitive emotion regulation of sadness in healthy children, Andy C. Belden, Joan L. Luby, David Pagliaccio, and Deanna M. Barch
Retinopathy and clinical outcomes in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia, Natalie A. Bello, Marc A. Pfeffer, Hicham Skali, Janet B. McGill, Jerome Rossert, Kurt A. Olson, Larry Weinrauch, Mark E. Cooper, Dick de Zeeuw, Peter Rossing, John J. V. McMurray, Scott D. Solomon, and Trial to Reduce cardiovascular Events with Aranesp Therapy (TREAT) Investigators
Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury, Rachel E. Bennett and David L. Brody
Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma, Thomas M. Bennett, Donna S. Mackay, Carla J. Siegfried, and Alan Shiels
Driving self-restriction and age: A study of emergency department patients, Marian E. Betz, Christopher R. Carpenter, Emma Genco, and David B. Carr
Developmental differences in masked form priming are not driven by vocabulary growth, Adeetee Bhide, Bradley L. Schlaggar, and Kelly Anne Barnes
Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing, Seweryn Bialasiewicz, Jodie McVernon, Terry Nolan, Stephen B. Lambert, Guoyan Zhao, David Wang, Michael D. Nissen, and Theo P. Sloots
Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6, Martina Bielaszewska, Roswitha Schiller, Lydia Lammers, Andreas Bauwens, Angelika Fruth, Barbara Middendorf, M. Alexander Schmidt, Phillip I. Tarr, Ulrich Dobrindt, Helge Karch, and Alexander Mellmann
Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors, Gabriel A. Bien-Willner and Robi D. Mitra
Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia, Kevin J. Black, Abraham Z. Snyder, Jonathan W. Mink, Veeral N. Tolia, Fredy J. Revilla, Stephen M. Moerlein, and Joel S. Perlmutter
Case records of the Massachusetts General Hospital. Case 1-2014. A 32-year-old man with loss of vision and a rash, Melvin S. Blanchard, Javier M. Romero, and Mai P. Hoang
Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver, Valerie Blanc, Eddie Park, Sabine Schaefer, Melanie MIller, Yiing Lin, Susan Kennedy, Anja M. Billing, Hisham Ben Hamidane, Johannes Graumann, Ali Mortazavi, Joseph H. Nadeau, and Nicholas O. Davidson
Exertional sickling: Questions and controversy, Morey A. Blinder and Sarah Russel
How to avoid microaspiration? A key element for the prevention of ventilator-associated pneumonia in intubated ICU patients, Stijn I. Blot, Jan Poelaert, and Marin Kollef
Outcome of all-inside second-generation meniscal repair: Minimum five-year follow-up, Ljiljana Bogunovic, Lisa M. Kruse, Amanda K. Haas, Laura J. Huston, and Rick W. Wright
The changing immune system in sepsis: Is individualized immuno-modulatory therapy the answer?, Jonathan S. Boomer, Jonathan M. Green, and Richard S. Hotchkiss
Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo, Marie K. Bosch, Jeanne M. Nerbonne, and David M. Ornitz
Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus, Sandip K. Bose, Hangeun Kim, Keith Meyer, Nathan Wolins, Nicholas O. Davidson, and Ranjit Ray
Treatment of stage I lung cancer in high-risk and inoperable patients: SBRT vs. RFA vs. sublobar resection, Matthew J. Bott and Traves Crabtree
A new measure of fear of falling: psychometric properties of the fear of falling questionnaire revised (FFQ-R), Emily S. Bower, Julie L. Wetherell, C. C. Merz, Andrew J. Petkus, Vanessa L. Malcarne, and Eric J. Lenze
SkpA restrains synaptic terminal growth during development and promotes axonal degeneration following injury, E. J. Brace, Chunlai Wu, Vera Valakh, and Aaron DiAntonio
What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander R. Vaccaro, and Jeffrey C. Wang
Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis, Matthew R. Brier, Jewell B. Thomas, and Beau M. Ances
PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells, Michael D. Brooks, Erin Jackson, Nicole M. Warrington, Jingqin Luo, Jason T. Forys, Sara Taylor, Diane D. Mao, Jeffrey R. Leonard, Albert H. Kim, David Piwnica-Worms, Robi D. Mitra, and Joshua B. Rubin
Total knee arthroplasty after previous knee surgery, Robert H. Brophy, Benjamin L. Gray, Ryan M. Nunley, Robert L. Barrack, and John C. Clohisy
Symptoms of pain do not correlate with rotator cuff tear severity, Robert H. Brophy, Matthew V. Smith, Rick W. Wright, and et al
Rapid ertapenem susceptibility testing and Klebsiella pneumoniae carbapenemase phenotype detection in Klebsiella pneumoniae isolates by use of automated microscopy of immobilized live bacterial cells, Carey-Ann D. Burnham, Rachel A. Frobel, Monica L. Herrera, Brian L. Wickes, and D. J. Diekema
De novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma, Jason P. Burnham, Benjamin S. Thomas, Sergio E. Trevino, Erin McElvania TeKippe, Carey-Ann D. Burnham, and F. Matthew Kuhlmann
Resting state functional connectivity in early blind humans, Harold Burton, Abraham Z. Snyder, and Marcus E. Raichle
A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, and CRONICAS Cohort Study Group
Cardiometabolic outcomes in children and adolescents following discontinuation of long-term risperidone treatment, Chadi A. Calarge, Ginger Nicol, Janet A. Schlechte, and Trudy L. Burns
Dorsal and ventral attention systems underlie social and symbolic cueing, Alicia Callejas, Gordon L. Shulman, and Maurizio Corbetta
miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain, Dominique Cannella, Marie-Pierre Brenier-Pinchart, Laurence Braun, Jason M. van Rooyen, Alexandre Bougdour, Olivier Bastien, Michael S. Behnke, Rose-Laurence Curt, Aurelie Curt, Jeroen P.J. Saeij, L. David Sibley, Herve Pelloux, and Mohamed-Ali Hakimi
Pervasive transcription of a herpesvirus genome generates functionally important RNAs, Susan P. Canny, Tiffany A. Reese, L. Steven Johnson, Xin Zhang, Amal Kambal, Erning Duan, Catherine Y. Liu, and Herbert W. Virgin
Resting-state modulation of alpha rhythms by interference with angular gyrus activity, Paolo Capotosto, Claudio Babiloni, Gian Luca Romani, and Maurizio Corbetta
Sex dependent risk factors for mortality after myocardial infarction: Individual patient data meta-analysis, Robert M. Carney, Kenneth E. Freedland, and et al