Submissions from 2014
Baseline hypovitaminosis D is not associated with poor clinical outcomes in osteoarticular infections, J Marschall, J. W.S. Lewis, D. K. Warren, H. M. Babcock, R. L. Barrack, and V. J. Fraser
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation, Catherine Martel, Gwendalyn J. Randolph, and et al
Slope of the anterior mitral valve leaflet: A new measurement of left ventricular unloading for left ventricular assist devices and systolic dysfunction, Sara C. Martinez, Elisa A. Bradley, Eric L. Novak, Ravi Rasalingam, Ari M. Cedars, Gregory A. Ewald, Scott C. Silvestry, and Susan M. Joseph
Helminth.net: expansions to Nematode.net and an introduction to Trematode.net., John Martin, Bruce A. Rosa, Philip Ozersky, Kymberlie Hallsworth-Pepin, Xu Zhang, Veena Bhonagiri-Palsikar, Rahul Tyagi, Qi Wang, Young-Jun Choi, Xin Gao, Samantha N. McNulty, Paul J. Brindley, and Makedonka Mitreva
Feasibility of isotope harvesting at a projectile fragmentation facility: ⁶⁷Cu, Tara Mastren, Aranh Pen, Graham F. Peaslee, Nick Wozniak, Shaun Loveless, Scott Essenmacher, Lee G. Sobotka, David J. Morrissey, and Suzanne E. Lapi
The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina, Tomohiro Masuda, Xiaodong Zhang, Cindy Berlinicke, Jun Wan, Anitha Yerrabelli, Elizabeth A. Conner, Sten Kjellstrom, Ronald Bush, Snorri S. Thorgeirsson, Anand Swaroop, Shiming Chen, and Donald J. Zack
Public perception regarding anterior cruciate ligament reconstruction, Matthew J. Matava, Daniel R. Howard, Landon Polakof, and Robert H. Brophy
Economic evaluation of access to musculoskeletal care: The case of waiting for total knee arthroplasty, Richard C. Mather III, Kevin T. Hug, Lori A. Orlando, Tyler Steven Watters, Lane Koenig, Ryan M. Nunley, and Michael P. Bolognesi
MicroRNAs in the stressed heart: Sorting the signal from the noise, Scot J. Matkovich
Transcription factor regulation and chromosome dynamics during pseudohyphal growth, David Mayhew and Robi D. Mitra
The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells, Joseph Mazar, Wei Zhao, Ahmad M. Khalil, Bongyong Lee, John Shelley, Subramaniam S. Govindarajan, Fumiko Yamamoto, Maya Ratnam, Muhammad Nauman Aftab, Sheila Collins, Brian N. Finck, Xianlin Han, John S. Mattick, Marcel E. Dinger, and Ranjan J. Perera
Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells, Sarah H. McBride, Jennifer A. McKenzie, Bronwyn S. Bedrick, Paige Kuhlmann, Jill D. Pasteris, Vicki Rosen, and Matthew J. Silva
Macrolides are associated with a better survival rate in patients hospitalized with community-acquired but not healthcare-associated pneumonia, Colleen McEvoy, Scott T. Micek, Richard M. Reichley, Jason Kan, Alex Hoban, Justin Hoffmann, Andrew F. Shorr, and Marin H. Kollef
Exploring physical exposures and identifying high-risk work tasks within the floor layer trade, Jamie McGaha, Kim Miller, Alexis Descatha, Laurie Welch, Bryan Buchholz, Bradley A. Evanoff, and Ann Marie Dale
The SGLT2 inhibitor empagliflozin for the treatment of type 2 diabetes mellitus: A bench to bedside review, Janet B. McGill
Systems biology studies of adult Paragonimus lung flukes facilitate the identification of immunodominant parasite antigens, Samantha N. McNulty, Peter U. Fischer, R Reid Townsend, Kurt C. Curtis, Gary J. Weil, and Makedonka Mitreva
Single haplotype assembly of the human genome from a hydatidiform mole, Karyn Meltz Steinberg, Valerie A. Schneider, Tina A. Graves-Lindsay, Robert S. Fulton, Richa Agarwala, John Huddleston, Sergey A. Shiryev, Aleksandr Morgulis, Urvashi Surti, Wesley C. Warren, Deanna M. Church, Evan E. Eichler, and Richard K. Wilson
Clinical implications for patients treated inappropriately for community-acquired pneumonia in the emergency department, Scott T. Micek, Adam Lang, Brian M. Fuller, Nicholas B. Hampton, and Marin H. Kollef
SciClone: Inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution, Christopher A. Miller, Brian A. White, Nathan D. Dees, Malachi Griffith, John S. Welch, Obi L. Griffith, Ravi Vij, Michael H. Tomasson, Timothy A. Graubert, Matthew J. Walter, Matthew J. Ellis, William Schierding, John F. DiPersio, Timothy J. Ley, Elaine R. Mardis, Richard K. Wilson, and Li Ding
Brain–behavior relationships in the experience and regulation of negative emotion in healthy children: Implications for risk for childhood depression, Jonathan M. Mobley, Eric H. Kim, Jeffrey A. Larson, Robert S. Figenshau, Joel M. Vetter, Michael H. Johnson, and Sam B. Bhayani
Patients with pathologically proven renal disease have similar declines in renal function following robot-assisted partial nephrectomy, Jonathan M. Mobley, Eric H. Kim, Jeffrey A. Larson, Robert S. Figenshau, Joel M. Vetter, Michael H. Johnson, and Sam B. Bhayani
In vivo evaluation of a reverse thermosensitive polymer for ureteroscopy with laser lithotripsy: Porcine model, Jonathan M. Mobley, Goutham Vemana, Marshall Strother, Robert Sherburne Figenshau, Joel M. Vetter, Jeffrey Larson, and Brian M. Benway
The role of laser interstitial thermal therapy in enhancing progression-free survival of difficult-to-access high-grade gliomas: A multicenter study, Alireza M. Mohammadi, Ammar H. Hawasli, Analiz Rodriguez, Jason L. Schroeder, Adrian W. Laxton, Paul Elson, Stephen B. Tatter, Gene H. Barnett, and Eric C. Leuthardt
Pulmonary phaeohyphomycosis caused by phaeoacremonium in a kidney transplant recipient: Successful treatment with posaconazole, Saivaralaxmi Monaganti, Carlos A Q Santos, Andrea Markwardt, Morgan A. Pence, and Daniel C. Brennan
Soft-tissue abnormalities associated with treatment-resistant and treatment-responsive clubfoot: Findings of MRI analysis, Daniel K. Moon, Christina A. Gurnett, Hyuliya Aferol, Marilyn J. Siegel, Paul K. Commean, and Matthew B. Dobbs
Using the internet to seek information about genetic and rare diseases: A case study comparing data from 2006 and 2011, Tamandra Morgan, Johanna Schmidt, Christy Haakonsen, Janine Lewis, Maria Della Rocca, Stephanie Morrison, Barbara Biesecker, and Kimberly A. Kaphingst
Gout in a 15-year-old boy with juvenile idiopathic arthritis: A case study, Hallie Morris, Kristen Grant, Geetika Khanna, and Andrew J. White
Significance of asymptomatic persistent epstein-barr viral load in pediatric renal transplant recipients: North American pediatric renal trials and collaborative studies report, Asha Moudgil, Karen Martz, Therese Moore, William E. Harmon, and Vikas R. Dharnidharka
Treatment of pagetoid reticulosis with intensity modulated radiation therapy, Charles Mount, Daniel Ferraro, Alejandro Gru, Matthew Bradbury, Lynn Cornelius, and Hiram Gay
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria, Kenneth M. Murphy and et al
The 2013 symposium on pathology data integration and clinical decision support and the current state of field, Rakesh Nagarajan and et al.
Complete response and prolonged disease-free survival in a patient with recurrent duodenal adenocarcinoma treated with bevacizumab plus FOLFOX6, Gayathri Nagaraj, Yousef Zarbalian, Karin Flora, and Benjamin R. Tan Jr.
Role of liver biopsy in nonalcoholic fatty liver disease, ILKe Nalbantoglu and Elizabeth M. Blunt
Factors affecting outcome after structural failure of repaired rotator cuff tears, Surena Namdari, Ryan P. Donegan, Aaron M. Chamberlain, Leesa M. Galatz, Ken Yamaguchi, and Jay D. Keener
Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis, Marcia Nascimento, Stanley C. Huang, Amber Smith, Bart Everts, Wing Lam, Elizabeth Bassity, Emmanuel L. Gautier, Gwendalyn J. Randolph, and Edward J. Pearce
Clinical presentation and disease characteristics of femoroacetabular impingement are sex-dependent, Jeffrey J. Nepple, Cassandra N. Riggs, James R. Ross, and John C. Clohisy
Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome, Majesta O'Bleness, Veronica B. Searles, C. Michael Dickens, David Astling, Derek Albracht, Angel C.Y. Mak, Yvonne Y.Y. Lai, Chin Lin, Catherine Chu, Tina Graves, Pui-Yan Kwok, Richard K. Wilson, and James M. Sikela
Key issues and opportunities in the evolving health-care marketplace: AOA critical issues, Kristin Olds Glavin, Daniel B. Murrey, Joel C. Porter, Donald Brunn, and Rick W. Wright
Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration, Patrick R. O'Neill and N. Gautam
Simultaneous bilateral or unilateral carpal tunnel release? A prospective cohort study of early outcomes and limitations, Daniel A. Osei, Ryan P. Calfee, Jeffrey G. Stepan, Martin I. Boyer, Charles A. Goldfarb, and Richard H. Gelberman
Brain-behavior relationships in the experience and regulation of negative emotion in healthy children: Implications for risk for childhood depression, David Pagliaccio, Joan L. Luby, Katherine R. Luking, Andrew C. Belden, and Deanna M. Barch
Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion, May M. Paing and Niraj H. Tolia
Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes, Pankaj Pal, Julie M. Fox, Michael S. Diamond, and et al
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using αvβ3-targeted theranostic nanoparticles, Dipanjan Pan, Anne H. Schmieder, Kezheng Wang, Xiaoxia Yang, Angana Senpan, Grace Cui, Kendall Killgore, Benjamin Kim, John S. Allen, Huiying Zhang, Shelton D. Caruthers, Baozhong Shen, Samuel A. Wickline, and Gregory M. Lanza
Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice, Joanna E. Pankiewicz, Maitea Guridi, Jungsu Kim, Ayodeji A. Asuni, Sandrine Sanchez, Patrick M. Sullivan, David M. Holtzman, and Martin J. Sadowski
Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer, Roheena Z. Panni, Dominic E. Sanford, Brian A. Belt, Jonathan B. Mitchem, Lori A. Worley, Brian D. Goetz, Pinku Mukherjee, Andrea Wang-Gillam, Daniel C. Link, David G. DeNardo, S. Peter Goedegebuure, and David C. Linehan
Age-related changes in cervical sagittal range of motion and alignment, Moon S. Park, Seong-Hwan Moon, Hwan-Mo Lee, Tae-Hwan Kim, Jae K. Oh, Ji H. Nam, and K. D. Riew
The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice, Charlyn G. Partridge, Gloria L. Fawcett, Bing Wang, Clay F. Semenkovich, and James M. Cheverud
The multiple signaling modalities of adhesion G protein-coupled receptor GPR126 in development, Chinmoy Patra, Kelly R. Monk, and Felix B. Engel
Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIB procollagen and down-regulation of cholesterol and lipid homeostasis, Debabrata Patra, Elizabeth DeLassus, Guosheng Liang, and Linda J. Sandell
An allometric scaling relationship in the brain of preterm infants, Rachel A. Paul, Christopher D. Smyser, Cynthia E. Rogers, Ian English, Michael Wallendorf, Dimitrios Alexopoulos, Erin J. Meyer, David C. Van Essen, Jeffrey J. Neil, and Terrie E. Inder
Methodological challenges and solutions in auditory functional magnetic resonance imaging, Jonathan E. Peelle
Photo quiz: A 58-year-old female with altered mental status, Morgan A. Pence and Carey-Ann D. Burnham
Outcome for children with metastatic solid tumors over the last four decades, Stephanie M. Perkins, Eric T. Shinohara, Todd DeWees, and Haydar Frangoul
Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study, Joel S. Perlmutter, Stacey Barton, Shineeka Kaye Smith, and et al
A rare sequence variant in intron 1 of THAP1 is associated with primary dystonia, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, and et al
Human cytomegalovirus pUL79 Is an elongation factor of RNA polymerase II for viral gene transcription, Yi-Chieh Perng, Jessica A. Campbell, Deborah J. Lenschow, and Dong Yu
Gait-related brain activity in people with Parkinson disease with freezing of gait, Daniel S. Peterson, Kristen A. Pickett, Ryan Duncan, Joel Perlmutter, and Gammon M. Earhart
Increased iron sequestration in alveolar macrophages in chronic obtructive pulmonary disease, Quentin Philippot, Gaetan Deslee, Tracy L. Adair-Kirk, Jason C. Woods, Derek Byers, Susan Conradi, Sandra Dury, Jeanne Marie Perotin, Francois Lebargy, Christelle Cassan, Richard Le Naour, Michael J. Holtzman, and Richard A. Pierce
Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis, Amelia K. Pinto, Hilario J. Ramos, Xiaobo Wu, Shilpa Aggarwal, Bimmi Shrestha, Matthew Gorman, Kristin Y. Kim, Mehul S. Suthar, John P. Atkinson, Michael Gale Jr., and Michael S. Diamond
Routine testing for anaerobic bacteria in cerebrospinal fluid cultures improves recovery of clinically significant pathogens, Meredith E. Pittman, Benjamin S. Thomas, Meghan A. Wallace, Carol J. Weber, and Carey-Ann D. Burnham
Streptococcus pyogenes polymyxin B-resistant mutants display enhanced exportal integrity, Gary C. Port, Luis A. Vega, Andrew B. Nylander, and Michael G. Caparon
Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference, George S. Portugal, Ream Al-Hasani, Amanda K. Fakira, Jose L. Gonzalez-Romero, Zare Melyan, Jordan G. McCall, Michael R. Bruchas, and Jose A. Moron
Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry, Deborah MB Post, Jason M. Held, Margaret R. Ketterer, Nancy J. Phillips, Alexandria Sahu, Michael A. Apicella, and Bradford W. Gibson
Missed opportunities: Racial and neighborhood socioeconomic disparities in emergency colorectal cancer diagnosis and surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, and Mario Schootman
Molecularly targeted therapies in multiple myeloma, Pilar de la Puente, Barbara Muz, Feda Azab, Micah Luderer, and Abdel Kareem Azab
Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe, Xudong Qiu, James R. Johnson, Bradley S. Wilson, Seth T. Gammon, David Piwnica-Worms, and Edward M. Barnett
Epidemiology of blunt head trauma in children in U.S. Emergency Departments, Kimberly S. Quayle, Elizabeth C. Powell, Prashant Mahajan, John D. Hoyle, Frances M. Nadel, Mohammed K. Badawy, Jeff E. Schunk, Rachel M. Stanley, Michelle Miskin, Shireen M. Atabaki, Peter S. Dayan, James F. Holmes, and Nathan Kuppermann
Opposing brain differences in 16p11.2 deletion and duplication carriers, Abid Y. Qureshi, Sophia Mueller, Abraham Z. Snyder, Pratik Mukherjee, Jeffrey I. Berman, Timothy P. L. Roberts, Srikantan S. Nagarajan, John E. Spiro, Wendy K. Chung, Elliott H. Sherr, and Randy L. Buckner
Diffusion tensor imaging in children with unilateral hearing loss: A pilot study, Tara Rachakonda, Joshua S. Shimony, Rebecca S. Coalson, and Judith E.C. Lieu
The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy, Cara Rada, Nan Lin, Sarah K. England, and et al
AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake, Ramachandran Rashmi, Carl DeSelm, Cynthia Helms, Anne Bowcock, Buck E. Rogers, Janet Rader, Perry W. Grigsby, and Julie K. Schwarz
IL-15 deficient Tax mice reveal a role for IL-1α in tumor immunity, Daniel A. Rauch, John C. Harding, and Lee Ratner
Cardiac and renal effects of atrasentan in combination with enalapril and paricalcitol in uremic rats, Cynthia Ritter, Sarah Zhang, Jane L. Finch, Helen Liapis, Edu Suarez, Leon Ferder, James Delmez, and Eduardo Slatopolsky
Illustrated techniques for performing the Cox-Maze IV procedure through a right mini-thoracotomy, Jason O. Robertson, Lindsey L. Saint, Jeremy E. Leidenfrost, and Ralph J. Damiano Jr.
Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis de Lecea, and David M. Holtzman
Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer, Rizwan Romee, Jeffrey W. Leong, and Todd A. Fehniger
Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum, Bruce A. Rosa, Douglas P. Jasmer, and Makedonka Mitreva
The role of neutrophil myeloperoxidase in models of lung tumor development, Amy Rymaszewski, Everett Tate, Joannes P. Yimbesalu, Andrew E. Gelman, Jason A. Jarzembowski, Hao Zhang, Kirkwood A. Pritchard Jr., and Haris G. Vikis
Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: Evidence for pleiotropy, Brooke Sadler, Gabe Haller, Arpana Agrawal, Rob Culverhouse, Kathleen Bucholz, Andy Brooks, Jay Tischfield, Eric O. Johnson, Howard Edenberg, Marc Schuckit, Nancy Saccone, Laura Bierut, and Alison Goate
How I do it: Minimally invasive Cox-Maze IV procedure, Lindsey L. Saint, Christopher P. Lawrance, Jeremy E. Leidenfrost, Jason O. Roberston, and Ralph J. Damiano Jr.
Critical glycosylated residues in exon three of erythrocyte Glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity, Nichole D. Salinas, May M. Paing, and Niraj H. Tolia
Sonography of acute appendicitis and its mimics in children, Kiran M. Sargar and Marilyn J. Siegel
Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis, Nayan J. Sarma, Venkataswarup Tiriveedhi, Jeffrey S. Crippin, William C. Chapman, and Thalachallour Mohanakumar
Risk-stratified patients with resectable soft tissue sarcoma benefit from epirubicin-based adjuvant chemotherapy, Aaron D. Schenone, Jingqin Luo, Luke Montgomery, Daniel Morgensztern, Douglas R. Adkins, and Brian A. Van Tine
BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathway, Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, and Victoria P. Frieden-Korovkina
Shiga toxin-producing Escherichia coli: A single-center, 11-year pediatric experience, Emily I. Schindler, Patricia Sellenriek, Gregory A. Storch, Phillip I. Tarr, and Carey-Ann D. Burnham
Dendritic cells in dengue virus infection: Targets of virus replication and mediators of immunity, Michael A. Schmid, Michael S. Diamond, and Eva Harris
Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and Major Depressive Disorder, Andrew J. Schrage, Michele L. Pergadia, Pamela A. F. Madden, and et al
Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling, Rebecca C. Schugar, Ashley R. Moll, D. Andre d'Avignon, Carla J. Weinheimer, Attila Kovacs, and Peter A. Crawford
Targeting hepatic glycerolipid synthesis and turnover to treat fatty liver disease, George G. Schweitzer and Brian N. Finck
Provision of no-cost, long-acting contraception and teenage pregnancy., Gina M. Secura, Tessa Madden, Colleen McNicholas, Jennifer Mullersman, Christina M. Buckel, Qiuhong Zhao, and Jeffrey F. Peipert
Domain-general signals in the cingulo-opercular network for visuospatial attention and episodic memory, Carlo Sestieri, Maurizio Corbetta, Sara Spadone, Gian Luca Romani, and Gordon L. Shulman
Absence of calcium‐independent phospholipase A2β impairs platelet‐activating factor production and inflammatory cell recruitment in Trypanosoma cruzi‐infected endothelial cells, Janhavi Sharma, Christopher S. Eickhoff, Daniel F. Hoft, John O. Marentette, John Turk, and Jane McHowat
Immuno-PET of epithelial ovarian cancer: Harnessing the potential of CA125 for non-invasive imaging, Sai Kiran Sharma, Melinda Wuest, Monica Wang, Darryl Glubrecht, Bonnie Andrais, Suzanne E. Lapi, and Frank Wuest
Contribution of the highly conserved EaeH surface protein to enterotoxigenic Escherichia coli pathogenesis, Alaullah Sheikh, Qingwei Luo, Koushik Roy, Salwa Shabaan, Pardeep Kumar, Firdausi Qadri, and James M. Fleckenstein
Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9, Bang Shen, Kevin M. Brown, Tobie D. Lee, and L. David Sibley
Functional analysis of rhomboid proteases during Toxoplasma invasion, Bang Shen, Jeffrey S. Buguliskis, Tobie D. Lee, and L. David Sibley
Fluoroscopically guided extraforaminal cervical nerve root blocks: Analysis of epidural flow of the injectate with respect to needle tip position, Kyle Shipley, K. D. Riew, and Louis A. Gilula
Predictors of hospital mortality among septic ICU patients with Acinetobacter spp. bacteremia: A cohort study, Andrew F. Shorr, Marya D. Zilberberg, Scott T. Micek, and Marin H. Kollef