Submissions from 2014
The circuitry of abulia: Insights from functional connectivity MRI, J. S. Siegel, A. Z. Snyder, N. V. Metcalf, R. P. Fucetola, C. D. Hacker, J. S. Shimony, G. L. Shulman, and M. Corbetta
SIRT6 is required for normal retinal function, Dafne M. Silberman, Kenneth Ross, Pablo H. Sande, Shunsuke Kubota, Sridhar Ramaswamy, Rajendra S. Apte, and Raul Mostoslavsky
Spike-timing computation properties of a feed-forward neural network model, Drew B. Sinha, Noah M. Ledbetter, and Dennis L. Barbour
Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors, Terence T. Sio, Kenneth Chang, Ritujith Jayakrishnan, Difu Wu, Mary Politi, Dominique Malacarne, James Saletnik, and Maureen Chung
Progress in pediatric kidney transplantation, Jodi M. Smith and Vikas R. Dharnidharka
Multiple dietary supplements do not affect metabolic and cardio-vascular health, Andreea Soare, Edward P. Weiss, John O. Holloszy, and Luigi Fontana
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells, Dorothy K. Sojka, Beatrice Plougastel-Douglas, Liping Yang, Melissa A. Pak-Wittel, Maxim N. Artyomov, Yulia Ivanova, Chao Zhong, Julie M. Chase, Paul B. Rothman, Jenny Yu, Joan K. Riley, Jinfang Zhu, Zhigang Tian, and Wayne M. Yokoyama
Dynamic radiographic criteria for detecting pseudarthrosis following anterior cervical arthrodesis, Kwang-Sup Song, Chaiwat Piyaskulkaew, Tapanut Chuntarapas, Jacob M. Buchowski, Han Jo Kim, Moon Soo Park, Hyun Kang, and K. Daniel Riew
State practitioner insights into local public health challenges and opportunities in obesity prevention: A qualitative study, Katherine A. Stamatakis, Moira Lewis, Elaine C. Khoong, and Claire LaSee
Unexpected abrupt increase in left ventricular assist device thrombosis, Randall C. Starling, Nader Moazami, Scott C. Silvestry, Gregory Ewald, Joseph G. Rogers, Carmelo A. Milano, J Eduardo Rame, Michael A. Acker, Eugene H. Blackstone, John Ehrlinger, Lucy Thuita, Maria M. Mountis, Edward G. Soltesz, Bruce W. Lytle, and Nicholas G. Smedira
Expression of nampt in hippocampal and cortical excitatory neurons is critical for cognitive function, Liana Roberts Stein, David F. Wozniak, Joshua T. Dearborn, Shunsuke Kubota, Rajendra S. Apte, Yukitoshi Izumi, Charles F. Zorumski, and Shin-ichiro Imai
Impact of radiation therapy on survival in patients with triple‑negative breast cancer, Lauren T. Steward, Feng Gao, Marie A. Taylor, and Julie A. Margenthaler
Arterial spin labeling versus BOLD in direct challenge and drug-task interaction pharmacological fMRI, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, and Kevin J. Black
Distribution and medical impact of loss-of-function variants in the Finnish founder population, Nathan O. Stitziel and et al
Differentiating c8-t1 radiculopathy from ulnar neuropathy: A survey of 24 spine surgeons, Geoffrey E. Stoker, Han J. Kim, and K. D. Riew
Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline, Nicholas Stong, Zhong Deng, Ravi Gupta, Sufen Hu, Shiela Paul, Amber K. Weiner, Evan E. Eichler, Tina Graves, Catrina C. Fronick, Laura Courtney, Richard K. Wilson, Paul M. Lieberman, Ramana V. Davuluri, and Harold Riethman
Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation, Robert Strunk and et al
Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression, Priya Sudarsanam and Barak A. Cohen
Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons, Daniel W. Summers, Aaron DiAntonio, and Jeffrey Milbrandt
TCAB1: A potential target for diagnosis and therapy of head and neck carcinomas, Chong-kui Sun, Xiao-bo Luo, Ya-ping Gou, Ling Hu, Kun Wang, Chao Li, Zhen-ting Xiang, Ping Zhang, Xiang-li Kong, Chao-liang Zhang, Qin Yang, Jing Li, Li-ying Xiao, Yan Li, and Qian-ming Chen
Widespread contribution of transposable elements to the innovation of gene regulatory networks, Vasavi Sundaram, Yong Cheng, Zhihai Ma, Daofeng Li, Xiaoyun Xing, Peter Edge, Michael P. Snyder, and Ting Wang
Whole genome sequence analysis of the simulated systolic blood pressure in Genetic Analysis Workshop 18 family data: Long-term average and collapsing methods, Yun Ju Sung, Jacob Basson, and Dabeeru C. Rao
Comparison of two methods for analysis of gene-environment interactions in longitudinal family data: The Framingham heart study, Yun Ju Sung, Jeannette Simino, Rezart Kume, Jacob Basson, Karen Schwander, and D. C. Rao
Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone, Tony Sun, Michael J. Vasek, and Robyn S. Klein
Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development, Gaurav Swarnkar, Kaihua Zhang, Gabriel Mbalaviele, Fanxin Long, and Yousef Abu-Amer
Secondhand smoke exposure and severity of attention-deficit/hyperactivity disorder in preschoolers: A pilot investigation, Mini Tandon, Christina N. Lessov-Schlaggar, Rebecca Tillman, Melbourne F. Hovell, and Joan Luby
Proteasome inhibitors activate autophagy involving inhibition of PI3K-Akt-mTOR pathway as an anti-oxidation defense in human RPE cells, Bingrong Tang, Jingjing Cai, Lin Sun, Yiping Li, Jia Qu, Barbara Joy Snider, and Shengzhou Wu
Genome sequence of Escherichia coli O157:H7 strain 2886-75, associated with the first reported case of human infection in the United States, Phillip I. Tarr and et al
The role of muscle loading on bone (re)modeling at the developing enthesis, Alexander M. Tatara, Justin H. Lipner, Rosalina Das, H. Mike Kim, Nikunj Patel, Eleni Ntouvali, Matthew J. Silva, and Stavros Thomopoulos
Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile Virus infection, Larissa B. Thackray, Bimmi Shrestha, Justin M. Richner, Jonathan J. Miner, Amelia K. Pinto, Helen M. Lazear, and Michael Gale Jr.
Mycobacterium ulcerans infection imported from Australia to Missouri, USA, 2012, Benjamin Stuart Thomas, Thomas C. Bailey, Julu Bhatnagar, Jana M. Ritter, Brian D. Emery, Omar W. Jassim, Ian Kerst Hornstra, and Sarah L. George
Using written narratives in public health practice: A creative writing perspective, Tess Thompson and Matthew W. Kreuter
Evaluation of a chemoresponse assay as a predictive marker in the treatment of recurrent ovarian cancer: Further analysis of a prospective study, Chunqiao Tian, Daniel J. Sargent, Thomas C. Krivak, Matthew A. Powell, Michael J. Gabrin, Stacey L. Brower, and Robert L. Coleman
Diabetes and pancreatic cancer survival: A prospective cohort-based study, Adetunji T. Toriola, Rachael Z. Stolzenberg-Solomon, L. Dalidowitz, David C. Linehan, and Graham A. Colditz
Mechanistically distinct mouse models for CRX-associated retinopathy, Nicholas M. Tran, Alan Zhang, Xiaodong Zhang, Julie B. Huecker, Anne K. Hennig, and Shiming Chen
Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury, Huei-Ping Tzeng, Sarah Evans, Feng Gao, Kari Chambers, Veli K. Topkara, Natarajan Sivasubramanian, Philip M. Barger, and Douglas L. Mann
Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes, Junji Uchino, David T. Curiel, and Hideyo Ugai
Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2, Jason D. Ulrich, Mary Beth Finn, Yaming Wang, Alice Shen, Thomas E. Mahan, Hong Jiang, Floy R. Stewart, Laura Piccio, Marco Colonna, and David M. Holtman
Cryptococcus at work: Gene expression during human infection, Rajendra Upadhya, Maureen J. Donlin, and Jennifer K. Lodge
CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma, Ravindra Uppaluri, James S. Lewis Jr, and et al
Origin and consequences of the relationship between protein mean and variance, Francesco Luigi Massimo Vallania, Marc Sherman, Zane Goodwin, Ilaria Mogno, Barak Alon Cohen, and Robi David Mitra
Listening effort and accented speech, Kristen J. Van Engen and Jonathan E. Peelle
Speckle contrast optical tomography: A new method for deep tissue three-dimensional tomography of blood flow, Hari M. Varma, Claudia P. Valdes, Anna K. Kristoffersen, Joseph P. Culver, and Turgut Durduran
Treatment of gram - positive infections in critically ill patients, Cristina Vazquez-Guillamet and Marin H. Kollef
Association between the intake of alpha-linolenic acid and the risk of CHD, Mia S. Vedtofte, Marianne U. Jakobsen, Lotte Lauritzen, Eilis J. O'Reilly, Jarmo Virtamo, Paul Knekt, Graham Colditz, Göran Hallmans, Julie Buring, Lyn M. Steffen, Kimberly Robien, Eric B. Rimm, and Berit L. Heitmann
Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus, Babs E. Verstrepen, Zahra Fagrouch, Melanie van Heteren, Hester Buitendijk, Tom Haaksma, Niels Beenhakker, Giorgio Palu, Justin M. Richner, Michael S. Diamond, Willy M. Bogers, Luisa Barzon, Stefan Chabierski, Sebastian Ulbert, Ivanela Kondova, and Ernst J. Verschoor
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion, Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, and Brian N. Finck
The VWFA: It's not just for words anymore, Alecia C. Vogel, Steven E. Petersen, and Bradley L. Schlaggar
Diabetes mellitus increases risk for colorectal adenomas in younger patients, Hongha T. Vu, Nneke Ufere, Yan Yan, Jean S. Wang, Dayna S. Early, and Jill E. Elwing
PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma, Nina D. Wagner-Johnston and et al
Identification of Alternative Transcripts Encoding the Essential Murine Gammaherpesvirus Lytic Transactivator RTA, Brian S. Wakeman, L. Steven Johnson, Clinton R. Paden, Kathleen S. Gray, Herbert W. Virgin, and Samuel H. Speck
Reactivation of multiple viruses in patients with sepsis, Andrew H. Walton, Jared T. Muenzer, David Rasche, Jonathan S. Boomer, Bryan Sato, Bernard H. Brownstein, Alexandre Pachot, Terrence L. Brooks, Elena Deych, William D. Shannon, Jonathan M. Green, Gregory A. Storch, and Richard S. Hotchkiss
Expert recommendations for implementing change (ERIC): Protocol for a mixed methods study, Thomas J. Waltz, Byron J. Powell, Matthew J. Chinman, Jeffrey L. Smith, Monica M. Matthieu, Enola K. Proctor, Laura J. Damschroder, and JoAnn E. Kirchner
NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection, Caihong Wang, Xuejun Yuan, Emily Ma, Graziella R. Mendonsa, Theo R. Plantinga, Lambertus A. Kiemeney, Sita H. Vermeulen, and Indira U. Mysorekar
Fruits of virus discovery: New pathogens and new experimental models, David Wang
Chromophore supply rate-limits mammalian photoreceptor dark adaptation, Jin-shan Wang, Soile Nymark, Rikard Frederiksen, Maureen E. Estevez, Susan Q. Shen, Joseph C. Corbo, M. Carter Cornwall, and Vladimir J. Kefalov
Adjuvant-specific regulation of long-term antibody responses by ZBTB20, Yinan Wang and Deepta Bhattacharya
Your Path to Transplant: A randomized controlled trial of a tailored computer education intervention to increase living donor kidney transplant, Amy D. Waterman, Mark L. Robbins, Andrea L. Paiva, John D. Peipert, Crystal S. Kynard-Amerson, Christina J. Goalby, LaShara A. Davis, Jessica L. Thein, Emily A. Schenk, Kari A. Baldwin, Stacy L. Skelton, Nicole R. Amoyal, and Leslie A. Brick
Smokers’ beliefs about the tobacco control potential of “a gene for smoking”: A focus group study, Erika A. Waters, Linda Ball, Kimberly Carter, and Sarah Gehlert
p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche, Marcus Watkins, Roberto Civitelli, and et al
Distinct lysosome phenotypes influence inflammatory function in peritoneal and bone marrow-derived macrophages, Kassandra Weber and Joel D. Schilling
Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation, Jeffrey J. Werner, Marcelo L. Garcia, Sarah D. Perkins, Kevin E. Yarasheski, Samuel R. Smith, Brian D. Muegge, Frank J. Stadermann, Christopher M. DeRito, Christine Floss, Eugene L. Madsen, Jeffrey I. Gordon, and Largus T. Angenent
Septic arthritis of a native knee joint due to Corynebacterium striatum, Lars F. Westblade, Farah Shams, Scott Duong, Oosman Tariq, Alan Bulbin, Dava Klirsfeld, Wei Zhen, Smita Sakaria, Bradley A. Ford, Carey-Ann D. Burnham, and Christine C. Ginocchio
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer, Nicole M. White, Christopher R. Cabanski, Jessica M. Silva-Fisher, Ha X. Dang, Ramaswamy Govindan, and Christopher A. Maher
Chemokines in the balance: Maintenance of homeostasis and protection at CNS barriers, Jessica L. Williams, David W. Holman, and Robyn S. Klein
Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system, Jessica L. Williams, Jigisha R. Patel, Brian P. Daniels, and Robyn S. Klein
Clinical trial design in the era of comparative effectiveness research, Anke C. Winter and Graham A. Colditz
Current perspectives on antibody-mediated rejection after lung transplantation, Chad A. Witt and Ramsey R. Hachem
Data requirements for electronic surveillance of healthcare-associated infections, Keith F. Woeltje, Michael Y. Lin, Michael Klompas, Marc Oliver Wright, Gianna Zuccotti, and William E. Trick
Long-term outcomes following a single corticosteroid injection for trigger finger, Robert D. Wojahn, Nicholas C. Foeger, Richard H. Gelberman, and Ryan P. Calfee
An fMRI study of the influence of a history of substance abuse on working memory-related brain activation in schizophrenia, Jessica A. Wojtalik and Deanna M. Barch
Quantitative evaluation of atlas-based highdensity diffuse optical tomography for imaging of the human visual cortex, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani
Metagenomic analysis of double-stranded DNA viruses in healthy adults, Kristine M. Wylie, Kathie A. Mihindukulasuriya, Yanjiao Zhou, Erica Sodergren, Gregory A. Storch, and George M. Weinstock
Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Jack M. Burchett, Dorothy R. Schuler, John R. Cirrito, Abhinav Diwan, and Jin-Moo Lee
Alzheimer’s therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity, Jinbin Xu, Chenbo Zeng, Carlos Cruchaga, Alison Goate, Robert H. Mach, and et al
Sterol biosynthesis is required for heat resistance but not extracellular survival in Leishmania, Wei Xu, Fong-Fu Hsu, Eda Baykal, Juyang Huang, and Kai Zhang
Blasts-more than meets the eye: Evaluation of post-induction day 21 bone marrow in CBFB rearranged acute leukemia, Xiangdong Xu and Eric J. Duncavage
Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders, Xiaoxiao Xu, Alan B. Wells, David R. O'Brien, Arye Nehorai, and Joseph D. Dougherty
Neuronal activity regulates extracellular tau in vivo, Kaoru Yamada, Jerrah K. Holth, Fan Liao, Floy R. Stewart, Thomas E. Mahan, Hong Jiang, John R. Cirrito, Tirth K. Patel, Katja Hochgräfe, Eva-Maria Mandelkow, and David M. Holtzman
Occupational sitting and weight status in a diverse sample of employees in Midwest metropolitan cities, 2012–2013, Lin Yang, J. Aaron Hipp, Christine M. Marx, and Ross C. Brownson
Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II, Hanako Yashiro, Andrew J. Loza, James B. Skeath, and Gregory D. Longmore
Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection, Ari Yasunaga, Sheri L. Hanna, Jianqing Li, Hyelim Cho, Patrick P. Rose, Anna Spiridigliozzi, Beth Gold, Michael S. Diamond, and Sara Cherry
Complications associated with the periacetabular osteotomy, Ira Zaltz, Geneva Baca, Young-Jo Kim, Perry Schoenecker, Robert Trousdale, Rafael Sierra, Daniel Sucato, Ernie Sink, Paul Beaulé, Michael B. Millis, David Podeszwa, and John C. Clohisy
HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors, Magda Zammataro, Maria Angela Sortino, Carmela Parenti, Robert W. Gereau IV, and Santina Chiechio
Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response, Haroun Zangger, Asrat Hailu, Chantal Desponds, Lon-Fye Lye, Natalia S. Akopyants, Deborah E. Dobson, Catherine Ronet, Hashim Ghalib, Stephen M. Beverley, and Nicolas Fasel
Comparison of perioperative outcomes of robot-assisted partial nephrectomy and open partial nephrectomy in patients with a solitary kidney, Homayoun Zargar, Sam Bhayani, Mohamad E. Allaf, Michael Stifelman, Craig Rogers, Jeffrey Larson, Mark W. Ball, Susan Marshall, Ramesh Kumar, Amr Fergany, Steven Campbell, and Jihad Kaouk
Intrawound vancomycin powder eradicates surgical wound contamination: An in vivo rabbit study, Lukas P. Zebala, Tapanut Chuntarapas, Michael P. Kelly, Michael Talcott, Suellen Greco, and K. Daniel Riew
Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data, Robert D. Zeigler and Barak A. Cohen
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers, Bo Zhang, Xiao Yun Xing, Jing Li, Rebecca F. Lowdon, Yan Zhou, Nan Lin, Baoxue Zhang, Vasavi Sundaram, Katherine B. Chiappinelli, Ian S. Hagemann, David G. Mutch, Paul J. Goodfellow, and Ting Wang
Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC, Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Brian A. Van Tine, Matthew J. Ellis, Andreas Herrlich, and Loren S. Michel
Application of noncollapsing methods to the gene-based association test: A comparison study using Genetic Analysis Workshop 18 data, Tian-Xiao Zhang, Yi-Ran Xie, and John P. Rice
Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein, Xiang Zhang, Hongjun Jin, Prashanth K. Padakanti, Junfeng Li, Hao Yang, Jinda Fan, Robert H. Mach, Paul Kotzbauer, and Zhade Tu
Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers, Yandong Zhang, Kathleen C. Baysac, Lian-Fai Yee, Anthony J. Saporita, and Jason D. Weber
Resistin stimulates expression of chemokine genes in chondrocytes via combinatorial regulation of C/EBPβ and NF-κB, Ziji Zhang, Zhiqi Zhang, Yan Kang, Changhe Hou, Xin Duan, Puyi Sheng, Linda J. Sandell, and Weiming Liao
Natural antisense transcripts regulate the neuronal stress response and excitability, Xingguo Zheng, Vera Valakh, Aaron DiAntonio, and Yehuda Ben-Shahar
Telomerase enzymatic component hTERT shortens long telomeres in human cells, Yun-Ling Zheng, Fan Zhang, Bing Sun, Juan Du, Chongkui Sun, Jie Yuan, Ying Wang, Lian Tao, Krishna Kota, Xuefeng Liu, Richard Schlegel, and Qin Yang
Conversion of fibroblasts to neural cells by p53 depletion, Di Zhou, Zhen Zhang, Li-Ming He, Juan Du, Fan Zhang, Chong-Kui Sun, Yu Zhou, Xiao-Wei Wang, Ge Lin, Ke-Ming Song, Ling-Gang Wu, and Qin Yang
Phenotypic and genotypic analysis of Clostridium difficile isolates: A single-center study, Yanjiao Zhou, Carey-Ann D. Burnham, Tiffany Hink, Lei Chen, Nurmohammad Shaikh, Aye Wollam, Erica Sodergren, George M. Weinstock, Phillip I. Tarr, and Erik R. Dubberke
The conjunctival microbiome in health and trachomatous disease: A case control study, Yanjiao Zhou, Martin J. Holland, Pateh Makalo, Hassan Joof, Chrissy H. Roberts, David C.W. Mabey, Robin L. Bailey, Matthew J. Burton, George M. Weinstock, and Sarah E. Burr
Exploration of bacterial community classes in major human habitats, Yanjiao Zhou, Kathie A. Mihindukulasuriya, Hongyu Gao, Patricio S. La Rosa, Kristine M. Wylie, John C. Martin, Karthik Kota, William D. Shannon, Makedonka Mitreva, Erica Sodergren, and George M. Weinstock
