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Submissions from 2017

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Current biologics for treatment of biliary tract cancers, Diana Y. Zhao and Kian-Huat Lim

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Gastrointestinal stromal tumors (GISTs): Point mutations matter in management, a review, Peter J. Oppelt, Angela C. Hirbe, and Brian A. Van Tine

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Immunotherapy in gastrointestinal cancers, Patrick Grierson, Kian-Huat Lim, and Manik Amin

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Investigator and independent review committee exploratory assessment and verification of tumor response in a non-Hodgkin lymphoma study, Robert R Ford, Robert W Ford, Michael O'Neal, Brad S Kahl, Ling Chen, Mihaela Munteanu, and Bruce D Cheson

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Molecular landscape and sub-classification of gastrointestinal cancers: A review of literature, Bita Fakhri and Kian-Huat Lim

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Postoperative atrial fibrillation: The role of the inflammatory response, Yosuke Ishii, Richard B Schuessler, Sydney L Gaynor, Kiyomi Hames, and Ralph J Damiano

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Promising therapeutics of gastrointestinal cancers in clinical trials, Lingling Du, Zheng Che, and Andrea Wang-Gillam

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The IMPROVEDD VTE risk score: Incorporation of D-dimer into the IMPROVE score to improve venous thromboembolism risk stratification, C. Michael Gibson, Alex C. Spyropoulos, Alexander T. Cohen, Russell D. Hull, Samuel Z. Goldhaber, Roger D. Yusen, Adrian F. Hernandez, Serge Korjian, Yazan Daaboul, Alex Gold, Robert A. Harrington, and Gerald Chi

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Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: A phase 2 consortium/stand up 2 cancer study, Nilofer S. Azad, Douglas Adkins, Joel Picus, Richard Piekarz, and et al

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GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients, Norimitsu Ban, Carla J. Siegfried, Jonathan B. Lin, Ying-Bo Shui, Julia Sein, Wolfgang Pita-Thomas, Abdoulaye Sene, Andrea Santeford, Mae Gordon, Rachel Lamb, Zhenyu Dong, Shannon C. Kelly, Valeria Cavalli, Jun Yoshino, and Rajendra S. Apte

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Incidental angiosarcoma of the pancreas: A case report of a rare, asymptomatic tumor, Patrick J Worth, Michael Turner, and Chet W Hammill

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Cholinergic, but not dopaminergic or noradrenergic, enhancement sharpens visual spatial perception in humans, Caterina Gratton, Sahar Yousef, Esther Aarts, Deanna L. Wallace, Mark D'Esposito, and Michael A. Silver

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LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients, Ta-Chiang Liu, Takeo Naito, Zhenqiu Liu, Kelli L VanDussen, Talin Haritunians, Dalin Li, Katsuya Endo, Yosuke Kawai, Masao Nagasaki, Yoshitaka Kinouchi, Dermot P. B. McGovern, Tooru Shimosegawa, Yoichi Kakuta, and Thaddeus S Stappenbeck

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Are there multiple kinds of episodic memory? An fMRI investigation comparing autobiographical and recognition memory tasks, Hung-Yu Chen, Adrian W. Gilmore, Steven M. Nelson, and Kathleen B. McDermott

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Personality profile and short-term treatment outcome in patients with alcohol dependence: A study from South India, Soundarya Soundararajan, Gitanjali Narayanan, Arpana Agrawal, and Pratima Murthy

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Subcutaneous peginterferon β-1a injection-site reaction experience and mitigation: Delphi analysis of the ALLOW study, Barry Hendin, DeRen Huang, Sibyl Wray, Robert T Naismith, Sheri Rosenblatt, Javier Zambrano, and Brian Werneburg

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MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2, Lauren J. Walker, Daniel W. Summers, Yo Sasaki, EJ Brace, Jeffrey Milbrandt, and Aaron DiAntonio

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1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function, Felicia Gomez, Mary F. Feitosa, and et al

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17β-Estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism, Shadaan Abid, ShangKui Xie, Moumita Bose, Philip W. Shaul, Lance S. Terada, Steven L. Brody, Philip J. Thomas, John A. Katzenellenbogen, Sung Hoon Kim, David E. Greenberg, and Raksha Jain

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24S-hydroxycholesterol and 25- hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation, Min-Yun Sun, Amanda Taylor, Charles F. Zorumski, and Steven Mennerick

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[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice, Mehdi Bin Samad, Md. Nurul Absar Bin Mohsin, Bodiul Alam Razu, Mohammad Tashnim Hossain, Sinayat Mahzabeen, Naziat Unnoor, Ishrat Aklima Muna, Farjana Akhter, Ashraf Ul Kabir, and J.M.A. Hannan

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A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0), Chad Tomlinson, LaDeana W. Hillier, Wesley C. Warren, and et al

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AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy, Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, and David M. Holtzman

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Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma, Megan Wu, Jennifer Guan, Chris Li, Simon Gunter, Labeeba Nusrat, Sheena Ng, Karan Dhand, Cindi Morshead, Albert Kim, and Sunit Das

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A bioluminescence reporter mouse that monitors expression of constitutively active β-catenin, Maria M. Szwarc, Ramakrishna Kommagan, Mary C. Peavey, Lan Hai, David M. Lonard, and John P. Lydon

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A C3(H20) recycling pathway is a component of the intracellular complement system, Michelle Elvington, M. Kathryn Liszewski, Paula Bertram, Hrishikesh S. Kulkarni, and John P. Atkinson

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Academic productivity among fellowship associated adult total joint reconstruction surgeons, Adam Z. Khan, Benjamin V. Kelley, Ankur D. Patel, David R. McAllister, and Natalie L. Leong

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A case of apparent upper-body freezing in Parkinsonism while using a wheelchair, Samuel T. Nemanich, Marie E. McNeely, Gammon M. Earhart, Scott A. Norris, and Kevin J. Black

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A case report of the clear cell variant of gallbladder carcinoma, Ravi Maharaj, Christo Cave, Kevin Sarran, Nigel Bascombe, Dilip Dan, Wesley Greaver, and Wayne A. Warner

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Accelerated return to sport after osteochondral autograft plug transfer, Brian C. Werner, Chris T. Cosgrove, C. Jan Gilmore, Matthew L. Lyons, Mark D. Miller, Stephen F. Brockmeier, and David R. Diduch

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A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development, Christie Ciarlo, Charles K. Kaufman, Beste Kinikoglu, Jonathan Michael, Song Yang, Christopher D'Amato, Sasja Blokzijl-Franke, Jeroen den Hertog, Thorsten M. Schlaeger, Yi Zhou, Eric Liao, and Leonard I. Zon

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A classification algorithm for predicting progression from normal cognition to mild cognitive impairment across five cohorts: The preclinical AD consortium, Alden L. Gross, Jason J. Hassenstab, Sterling C. Johnson, Lindsay R. Clark, Susan M. Resnick, Melissa Kitner-Triolo, Colin L. Masters, Paul Maruff, John C. Morris, Anja Soldan, Corinne Pettigrew, and Marilyn S. Albert

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A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma, Kian-Huat Lim, Feng Gao, Jingqin Luo, Lin Li, Vladamir M. Kushnir, Dayna S. Early, Daniel K. Mullady, Dengfeng Cao, Riad R. Azar, Andrea Wang-Gillam, and et al

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A comparative analysis between sequential boost and integrated boost intensity-modulated radiation therapy with concurrent chemotherapy for locally-advanced head and neck cancer, Gregory Vlacich, Mark J. Stavas, Praveen Pendyala, Shaeu-Chiann Chen, Yu Shyr, and Anthony J. Cmelak

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A comparison of medical education in Germany and the United States: From applying to medical school to the beginnings of residency, Dmitry Zavlin, Kevin T. Jubbal, Jonas G. Noé, and Bernd Gansbacher

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A comparison of per sample global scaling and per gene normalization methods for differential expression analysis of RNA-seq data, Xiaohong Li, Guy N. Brock, Eric C. Rouchka, Nigel G. F. Cooper, Dongfeng Wu, Timothy E. O'Toole, Ryan S. Gill, Abdallah M. Eteleeb, Liz O'Brien, and Sexh N. Rai

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A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii, Shaojun Long, Bryan Anthony, Lisa L. Drewry, and L. David Sibley

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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment, Haiyong Zhao and Kyunghee Choi

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Actin/myosin-V- and activity-dependent inter-synaptic vesicle exchange in central neurons, Michael W. Gramlich and Vitaly A. Klyachko

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Activity-dependence of synaptic vesicle dynamics, Luca A. Forte, Michael W. Gramlich, and Vitaly A. Klyachko

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Activity disengagement: Understanding challenges and opportunities for reengagement, Krista Fox, Nancy Morrow-Howell, Stephanie Herbers, Paula Battista, and Carolyn M. Baum

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Acute abdominal pain assessment in the emergency department: The experience of a Greek university hospital, Dimitrios Velissaris, Menelaos Karanikolas, Nikolaos Pantzaris, George Kipourgos, Vasileios Bampalis, Konstantina Karanikola, Eleftheria Fafliora, Christina Apostolopoulou, and Charalampos Gogos

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Acute CD47 blockade during ischemic myocardial reperfusion enhances phagocytosis-associated cardiac repair, Shuang Zhang, Xin-Yi Yeap, Matthew DeBerge, Nivedita K. Naresh, Kevin Wang, Zhengxin Jiang, Jane E. Wilcox, Steven M. White, John P. Morrow, Paul W. Burridge, Daniel Procissi, Evan A. Scott, William Frazier, and Edward B. Thorp

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Acute hypocalcemia and metabolic alkalosis in children on cation-exchange resin therapy, Aadil Kakajiwala, Kevin T. Barton, Elisha Rampolla, Christine Breen, and Madhura Pradhan

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Acute knockdown of Kv4.1 regulates repetitive firing rates and clock gene expression in the suprachiasmatic nucleus and daily rhythms in locomotor behavior, Tracy O. Hermanstyne, Daniel Granados-Fuentes, Rebecca L. Mellor, Erik D. Herzog, and Jeanne M. Nerbonne

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Addition of 24‐hour heart rate variability parameters to the Cardiovascular Health Study stroke risk score and prediction of incident stroke: The Cardiovascular Health Study, Rohan K. Bodapati, Jorge R. Kizer, Willem J. Kop, Hooman Kamel, and Phyllis K. Stein

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Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer, Lindsay M. Kuroki, Xingjian Jin, Igor P. Dmitriev, Elena A. Kashentseva, Matthew A. Powell, David G. Mutch, Allan B. Dietz, David T. Curiel, William G. Hawkins, and Dirk Spitzer

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Adherence and outcomes to direct oral anticoagulants among patients with atrial fibrillation: Findings from the Veterans Health Administration, Ryan T. Borne, Colin O'Donnell, Mintu P. Turakhia, Paul D. Varosy, Cynthia A. Jackevicius, Lucas N. Marzec, Frederick A. Masoudi, Paul L. Hess, Thomas M. Maddox, and P. Michael Ho

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Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming, Adilson Guilherme, David J. Pedersen, Elizabeth Henchey, Felipe S. Henriques, Laura V. Danai, Yuefei Shen, Batuhan Yenilmez, DaeYoung Jung, Jason K. Kim, Irfan J. Lodhi, Clay F. Semenkovich, and Michael P. Czech

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Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice, Taotao Xu, Hongting Jin, Yangjun Lao, Pinger Wang, Shanxing Zhang, Hongfeng Ruan, Qiang Mao, Li Zhou, Luwei Xiao, Peijian Tong, and Chengliang Wu

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A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias, Henrique Goldberg, Marco Antonio Mibielli, Carlos Pereira Nunes, Stephanie Wrobel Goldberg, Luiz Buchman, Spyros GE Mezitis, Helio Rzetelna, Lisa Oliveria, Mauro Geller, and Fernanda Wajnsztajn

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Advances in gut microbiome research, opening new strategies to cope with a western lifestyle, Gina P. Rogdriguez-Castaño, Alejandro Caro-Quintero, Alejandro Reyes, and Fernando Lizcano

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A full lifespan model of vertebrate lens growth, Hrvoje Šikić, Yanrong Shi, Snježana Lubura, and Steven Bassnett

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A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities, Yanyan Geng, Juan J. Ferreira, Victor Dzikunu, Alice Butler, Pascale Lybaert, Peng Yuan, Karl L. Magleby, Lawrence Salkoff, and Celia M. Santi

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A human antibody against Zika virus crosslinks the E protein to prevent infection, S. Saif Hasan, Andrew Miller, Gopal Sapparapu, Estefania Fernandez, Thomas Klose, Feng Long, Andrei Fokine, Jason C. Porta, Wen Jiang, Michael S. Diamond, James E. Crowe Jr., Richard J. Kuhn, and Michael G. Rossmann

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AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort, Samuel W. Reinhardt, Andrej Spec, Johanna Melendez, Andrea Alonzo Cordon, Ian Ross, William G. Powderly, and Carlos Mejia Villatoro

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A laminar organization for selective cortico-cortical communication, Rinaldo D. D'Souza and Andreas Burkhalter

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Allosteric HIV-1 integrase inhibitors lead to premature degradation of the viral RNA genome and integrase in target cells, Michaela K. Madison, Dana Q. Lawson, Jennifer Elliott, Ayse Naz Ozanturk, Pratibha C. Koneru, Dana Townsend, Manel Errando, Mamuka Kvaratskhelia, and Sebla B. Kutluay

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Altered sleep and EEG power in the P301S Tau transgenic mouse model, Jerrah K. Holth, Thomas E. Mahan, Grace O. Robinson, Andreia Rocha, and David M. Holtzman

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Alu insertion polymorphisms as evidence for population structure in baboons, Cody J. Steely, Jane Phillips-Conroy, and et al

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Alzheimer's disease pathology and shunt surgery outcome in normal pressure hydrocephalus, Sevil Yasar, Ignacio Jusue-Torres, Jennifer Lu, Jamie Robinson, Mira A. Patel, Barbara Crain, Kathryn A. Carson, Jamie Hoffberger, Sachin Batra, Eric Sankey, Abhay Moghekar, and Daniele Rigamonti

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A method for quantifying upper limb performance in daily life using accelerometers, Catherine E. Lang, Kimberly J. Waddell, Joseph W. Klaesner, and Marghuretta D. Bland

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A method to reconstruct and apply 3D primary fluence fortreatment delivery verification, Shi Liu, Thomas R. Mazur, Harold Li, Austen Curcuru, Olga L. Green, Baozhou Sun, Sasa Mutic, and Deshan Yang

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A microRNA feedback loop regulates global microRNA abundance during aging, Sachi Inukai, Zachary Pincus, Alexandre de Lencastre, and Frank J. Slack

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A multi-center field study of two point-of-care tests for circulating Wuchereria bancrofti antigenemia in Africa, Cedric B. Chesnais, Naomi-Pitchouna Awaca-Uvon, Fatorma K. Bolay, Michel Boussinesq, Peter U. Fischer, Lincoln Gankpala, Aboulaye Meite, Francois Missamou, Sébastien D. Pion, and Gary J. Weil

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A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion, Swapneel J. Patel, Guoyan Zhao, Vinay R. Penna, Eugene Park, Elvin J. Lauron, Ian B. Harvey, Wandy L. Beatty, Beatrice Plougastel-Douglas, Jennifer Poursine-Laurent, Daved H. Fremont, and Wayne M. Yokoyama

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Amyloid β–associated cognitive decline in the absence of clinical disease progression and systemic illness, Karra D. Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M. Laws, Ralph N. Martins, Stephanie Rainey-Smith, Joanne Robertson, Christopher C. Rowe, Olivier Salvado, Vincent Dore, Victor L. Villemagne, Peter J. Snyder, Colin L. Masters, and Paul Maruff

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An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations, Anne M. Fagan and et al

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An accurate and efficient method for large-scale SSR genotyping and applications, Lun Li, Zhiwei Fang, Junfei Zhou, Hong Chen, Zhangfeng Hu, Lifen Gao, Lihong Chen, Sheng Ren, Hongyu Ma, Long Lu, Weiziong Zhang, and Hai Peng

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An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition, William Vermi and et al

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Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer disease, Maria Victoria Fernandez, Jong Hun Kim, John P. Budde, Kathleen Black, Alexandra Medvedeva, Ben Saef, Yuetiva Deming, Jorge Del-Aguila, Laura Ibanez, Umber Dube, Oscar Harari, Joanne Norton, Rachel Chasse, John C. Morris, Alison Goate, Carlos Cruchaga, and et al.

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Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection, Rileen Sinha, Andrew G. Winer, Michael Chevinsky, Christopher Jakubowski, Ying-Bei Chen, Yiyu Dong, Satish K. Tickoo, Victor E. Reuter, Paul Russo, Jonathan A. Coleman, Chris Sander, James J. Hsieh, and A Ari Hakimi

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Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types, Runjun D. Kumar and Ron Bose

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Analytical characterization of Methyl-β-Cyclodextrin for pharmacological activity to reduce lysosomal cholesterol accumulation in Niemann-Pick disease type C1 cells, Rong Li, Jon Hao, Hideji Fujiwara, Miao Xu, Shu Yang, Sheng Dai, Yan Long, Manju Swaroop, Changhui Li, Mylinh Vu, Juan J. Marugan, Daniel S. Ory, and Wei Zheng

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An assessment of residents’ and fellows’ personal finance literacy: An unmet medical education need, Fahd A. Ahmad, Andrew J. White, Katherine M. Hiller, Richard Amini, and Donna B. Jeffe

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An audience research study to disseminate evidence about comprehensive state mental health parity legislation to US State policymakers: Protocol, Jonathan Purtle, Félice Lê-Scherban, Paul Shattuck, Enola K. Proctor, and Ross C. Brownson

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An efficient platform for astrocyte differentiation from human induced pluripotent stem cells, Julia TCW, Minghui Wang, Anna A. Pimenova, Kathryn R. Bowles, Brigham J. Hartley, Emre Lacin, Saima I. Machlovi, Rawan Abdelaal, Celeste M. Karch, Hemali Phatnani, Paul A. Slesinger, Bin Zhang, Alison M. Goate, and Kristen J. Brennand

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An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies, Francis B. Ntumngia, Camilla V. Pires, Samantha J. Barnes, Miriam T. George, Richard Thomson-Luque, Flora S. Kano, Jessica R.S. Alves, Darya Urusova, Dhelio B. Pereira, Niraj H. Tolia, Christopher L. King, Luzia H. Carvalho, and John H. Adams

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An evaluation of the prevalence of vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) in hospital food, Jennie H. Kwon, Kimberly A. Reske, Tiffany Hink, Sondra M. Seiler, Meghan A. Wallace, Kerry M. Bommarito, Carey-Ann D. Burnham, and Eric R. Dubberke

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An evolutionarily conserved pathway essential for orsay virus infection of Caenorhabditis elegans, Hongbing Jiang, Kevin Chen, Luis E. Sandoval, Christian Leung, and David Wang

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A new chicken genome assembly provides insight into avian genome structure, Wesley C. Warren, LaDeana W. Hillier, Chad Tomlinson, Patrick Minx, Milinn Kremitzki, Tina Graves, Chris Markovic, and et al

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Animal models of Zika virus infection, pathogenesis, and immunity, Thomas E. Morrison and Michael S. Diamond

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An IRF-3-, IRF-5-, and IRF-7-independent pathway of dengue viral resistance utilizes IRF-1 to stimulate type I and II interferon, Aaron F. Carlin, Emily M. Plummer, Edward A. Vizcarra, Nicholas Sheets, Yunichel Joo, William Tang, Jeremy Day, Jay Greenbaum, Christopher K. Glass, Michael S. Diamond, and Sujan Shresta

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An optimized, broadly applicable piggyBac transposon induction system, Zongtai Qi, Michael Nathaniel Wilkinson, Xuhua Chen, Sumithra Sankararaman, David Mayhew, and Robi David Mitra

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A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth, Ali Gholipour, Caitlin K. Rollins, Clemente Velasco-Annis, Abdelhakim Ouaalam, Alireza Akhondi-Asl, Onur Afacan, Cynthia M. Ortinau, Sean Clancy, Catherine Limperopoulos, Edward Yang, Judy A. Estroff, and Simon K. Warfield

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A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage, Diane J. Aum, Ananth K. Vellimana, Itender Singh, Eric Milner, James W. Nelson, Byung Hee Han, and Gregory J. Zipfel

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A novel method for the quantification of fatty infiltration in skeletal muscle, Nicole K. Blitz and Gretchen A. Meyer

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A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury, Taiji Ishii, Takehiko Ueyama, Michiko Shigyo, Masaaki Kohta, Takeshi Kondoh, Tomoharu Kuboyama, Tatsuya Uebi, Takeshi Hamada, David H. Gutmann, Atsu Aiba, Eiji Kohmura, Chihiro Tohda, and Naoaki Saito

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Anterior cingulate is a source of valence-specific information about value and uncertainty, Ilya E. Monosov

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Anthropometric discriminators of type 2 diabetes among White and Black American adults, Dale S. Hardy, Devita T. Stallings, Jane T. Garvin, Francine C. Gachupin, Hongyan Xu, and Susan B. Racette

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Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat, Gregory M. Lanza, John Jenkins, Anne H. Schmieder, Aigul Moldobaeva, Grace Cui, Huiying Zhang, Xiaoxia Yang, Qiong Zhong, Jochen Keupp, Ismail Sergin, Krishna S. Paranandi, Lindsey Eldridge, John S. Allen, Todd Williams, Michael J. Scott, Babak Razani, and Elizabeth M. Wagner

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Antibiotic prophylaxis is associated with subsequent resistant infections in children with an initial extended-spectrum-cephalosporin-resistant Enterobacteriaceae infection, Sibani Das, Amanda L. Adler, Arianna Miles-Jay, Matthew P. Kronman, Xuan Qin, Scott J. Weissman, Carey-Ann D. Burnham, Alexis Elward, Jason G. Newland, Rangaraj Selvarangan, Kaede V. Sullivan, Theoklis Zaoutis, and Danielle M. Zerr

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Antibiotics promote the sampling of luminal antigens and bacteria via colonic goblet cell associated antigen passages, Kathryn A. Knoop, Jenny K. Gustafsson, Keely G. McDonald, Devesha H. Kulkarni, Rachel Kassel, and Rodney D. Newberry

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Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects, Jennifer Govero, Michael S. Diamond, and et al

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Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San in db/db mice via activation of PI3K/Akt and AMPK pathways, Bailu Duan, Zhongqiu Zhao, Weifang Liao, Hui Xiong, Sisi Liu, Liang Yin, Tiexiang Gao, and Zhinan Mei

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Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats, Bailu Duan, Zhongqiu Zhao, Ling Lin, Jing Jin, Lijun Zhang, Hui Xiong, Na Ta, Tiexiang Gao, and Zhinan Mei

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Antipyretic therapy in critically ill septic patients: A systematic review and meta-analysis, Anne M. Drewry, Enyo A. Ablordeppey, Ellen T. Murray, Carolyn R.T. Stoll, Sonya R. Izadi, Catherine M. Dalton, Angela C. Hardi, Susan A. Fowler, Brian M. Fuller, and Graham A. Colditz

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A pathway for low zinc homeostasis that is conserved in animals and acts in parallel to the pathway for high zinc homeostasis, Nicholas Dietrich, Daniel L. Schneider, and Kerry Kornfeld

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A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor, Benjamin R. Tan and et al

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A phase 2, open-label, multi-center study of amuvatinib in combination with platinum etoposide chemotherapy in platinumrefractory small cell lung cancer patients, Lauren Averett Byers, Leora Horn, Jitendra Ghandi, Goetz Kloecker, Taofeek Owonikoko, Saiama Naheed Waqar, Maciej Krzakowski, Robert J. Cardnell, Junya Fujimoto, Pietro Taverna, Mohammad Azab, and Daivd Ross Camidge