Submissions from 2017
TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells, Pin Guo, Yanan Yu, Huanting Li, Daoxiang Zhang, Anjing Gong, Shifang Li, Wei Liu, Lei Cheng, Yongming Qiu, Weicheng Yao, Luo Li, and Yugong Feng
The Alzheimer's Disease Sequencing Project: Study design and sample selection, D. C. Koboldt, D. E. Larson, and et al
The aromatic amino acid hydroxylase genes AAH1 and AAH2 in Toxoplasma gondii contribute to transmission in the cat, Zi T. Wang, Shiv K. Verma, Jitender P. Dubey, and L. David Sibley
The association of genetic predisposition to depressive symptoms with non-suicidal and suicidal self-Injuries, Dominique F. Maciejewski, Miguel E. Renteria, Abdel Abdellaoui, Sarah E. Medland, Lauren R. Few, Scott D. Gordon, Pamela A.F. Madden, Grant Montgomery, Timothy J. Trull, Andrew C. Heath, Dixie J. Statham, Nicholas G. Martin, Brendan P. Zietsch, and Karin J.H. Verweij
The Auditory Nerve Overlapped Waveform (ANOW) detects small endolymphatic manipulations that may go undetected by conventional measurements, Jeffery T. Lichtenhan, Choongheon Lee, Farah Dubaybo, Kaitlyn A. Wenrich, and Uzma S. Wilson
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome, Jason J. Yi, Smita R. Paranjape, Matthew P. Walker, Rajarshi Choudhury, Justin M. Wolter, Giulia Fragola, Michael J. Emanuele, Michael B. Major, and Mark J. Zylka
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni, Kathrin K. Geyer, Umar H. Niazi, David Duval, Celine Cosseau, Chad Tomlinson, Iain W. Chalmers, Martin T. Swain, David Cutress, Utibe Bickham-Wright, Sabrina E. Munshi, Christoph Grunau, Timothy P. Yoshino, and Karl F. Hoffmann
The Brief Case: Bacteremia and vertebral osteomyelitis due to Staphylococcus schleiferi, Melanie L. Yarbrough, Yasir Hamad, Carey-Ann D. Burnham, and Ige A. George
The Brief Case: Central nervous system sparganosis in a 53-year-old Thai man, Abigail L. Carlson, Nattapol Pruetpongpun, Aubonphan Buppajarntham, Pansachee Damronglerd, Neil W. Anderson, and Anucha Apisarnthanarak
The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation, Anne C. Solga, Joseph A. Toonen, Yuan Pan, Patrick J. Cimino, Yu Ma, Guillaume A. Castillon, Scott M. Gianino, Mark H. Ellisman, Da Yong Lee, and David H. Gutmann
The Cyprinodon variegatus genome reveals gene expression changes underlying differences in skull morphology among closely related species, Ezra S. Lencer, Wesley C. Warren, Richard Harrison, and Amy R. McCune
The difficult gallbladder: A safe approach to a dangerous problem, B. Fernando Santos, L. Michael Brunt, and Michael J. Pucci
The E. coli molecular phenotype under different growth conditions, Mehmet U. Caglar, John R. Houser, Craig S. Barnhart, Daniel R. Boutz, Sean M. Carroll, Aurko Dasgupta, Walter F. Lenoir, Bartram L. Smith, Viswanadham Sridhara, Dariya K. Sydykova, Drew Vander Wood, Christopher J. Marx, Edward M. Marcotte, Jeffrey E. Barrick, and Claus O. Wilke
The E. coli molecular phenotype under different growth conditions, Mehmet U. Caglar, John R. Houser, Craig S. Barnhart, Daniel R. Boutz, Sean M. Carroll, Aurko Dasgupta, Walter F. Lenoir, Bartram L. Smith, Viswanadham Sridhara, Dariya K. Sydykova, Drew Vander Wood, Christopher J. Marx, Edward M. Marcotte, Jeffrey E. Barrick, and Claus O. Wilke
The effect of adding comorbidities to current centers for disease control and prevention central-line–associated bloodstream infection risk-adjustment methodology, Sarah S. Jackson, Surbhi Leekha, Laurence S. Magder, Lisa Pineles, Deverick J. Anderson, William E. Trick, Keith F. Woeltje, Keith S. Kaye, Kristen Stafford, Kerri Thom, Timothy J. Lowe, and Anthony D. Harris
The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey, Randy J. Bateman and et al
The electrically evoked compound action potential: From laboratory to clinic, Shuman He, Holly F.B. Teagle, and Craig A. Buchman
The emergence of network inefficiencies in infants with autism spectrum disorder, John R. Pruett Jr., Kelly N. Botteron, Robert C. McKinstry, and et al
The expanding toolkit of translating ribosome affinity purification, Joseph D. Dougherty
The genome and adult somatic transcriptome of the Mormyrid electric fish Paramormyrops kingsleyae, Jason R. Gallant, Mauricio Losilla, Chad Tomlinson, and Wesley C. Warren
The genomics of neonatal abstinence syndrome, F. Sessions Cole, Daniel J. Wegner, and Jonathan M. Davis
The Global Alliance for Infections in Surgery: Defining a model for antimicrobial stewardship—results from an international cross-sectional survey, Stephen Y. Liang and et al
The gut microbiome in atherosclerotic cardiovascular disease, Yangqing Peng and et al
The heritability of multi-modal connectivity in human brain activity, Giles L. Colclough, Stephen M. Smith, Thomas E. Nichols, Anderson M. Winkler, Stamatios N. Sotiropoulos, Matthew F. Glasser, David C. Van Essen, and Mark W. Woolrich
The impact of high grade glial neoplasms on human cortical electrophysiology, S. Kathleen Bandt, Jarod L. Roland, Mrinal Pahwa, Carl D. Hacker, David T. Bundy, Jonathan D. Breshears, Mohit Sharma, Joshua S. Shimony, and Eric C. Leuthardt
The islet-resident macrophage is in an inflammatory state and senses microbial products in blood, Stephen T. Ferris, Pavel N. Zakharov, Xiaoxiao Wan, Boris Calderon, Maxim N. Artyomov, Emil R. Unanue, and Javier A. Carrero
The landscape of extreme genomic variation in the highly adaptable Atlantic killifish, Noah M. Reid, Patrick Minx, Michael J. Montague, and Wesley C. Warren
The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia, Michael O. Alberti and et al
The mouse cortical meninges are the site of immune responses to many different pathogens, and are accessible to intravital imaging, Jonathan A. Coles, Phillip J. Stewart-Hutchinson, Elmarie Myburgh, and James M. Brewer
The Mycobacterium tuberculosis MmpL11 cell wall lipid transporter is important for biofilm formation, intracellular growth, and nonreplicating persistence, Catherine C. Wright, Fong Fu Hsu, Eusondia Arnett, Jennifer L. Dunaj, Patrick M. Davidson, Sophia A. Pacheco, Melanie J. Harriff, David M. Lewinsohn, Larry S. Schlesinger, and Georgiana E. Purdy
The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision, Frans Vinberg, Tian Wang, Alicia De Maria, Haiqing Zhao, Steven Bassnett, Jeannie Chen, and Vladimir J. Kefalov
The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication, Ben T. Cotton, Jennifer L. Hyde, Soroush T. Sarvestani, Stanislav V. Sosnovtsev, Kim Y. Green, Peter A. White, and Jason M. Mackenzie
The novel evolution of the sperm whale genome, Wesley C. Warren, Patrick Minx, Chad Tomlinson, Fabiana H. G. Farias, and et al
The nuclear receptor HIZR-1 uses zinc as a ligand to mediate homeostasis in response to high zinc, Kurt Warnhoff, Hyun C. Roh, Zuzana Kocsisova, Chieh-Hsiang Tan, Andrew Morrison, Damari Croswell, Daniel L. Schneider, and Kerry Kornfeld
The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling, Gao-Yuan Liu, Sung Ho Moon, Christopher M. Jenkins, Maoyin Li, Harold F. Sims, Shaoping Guan, and Richard W. Gross
The power of the few, Ran Chen, Yuan Pan, and David H. Gutmann
The practical use of genome sequencing data in the management of a feline colony pedigree, Fabiana H.G Farias, Chad Tomlinson, Jeffrey Labuda, Gerardo Perez-Camargo, Rondo Middleton, and Wesley C. Warren
The prevalence of cubital tunnel syndrome: A cross-sectional study in a U.S. metropolitan cohort, Tonya W. An, Bradley A. Evanoff, Martin I. Boyer, and Daniel A. Osei
The privilege of induction avoidance and calcineurin inhibitors withdrawal in 2 haplotype HLA matched white kidney transplantation, Zaid Brifkani, Daniel C. Brennan, Krista L. Lentine, Timothy A. Horwedel, Andrew F. Malone, Rowena Delos Santos, Thin Thin Maw, and Tarek Alhamad
The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent, Kalpana D. Acharya, Sabin A. Nettles, Katherine J. Sellers, Dana D. Im, Moriah Harling, Cassandra Pattanayak, Didem Vardar-Ulu, Cheryl F. Lichti, Shixia Huang, Dean P. Edwards, Deepak P. Srivastava, Larry Denner, and Marc J. Tetel
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques, Julie M. Fox, Soila Sukulpovi-Petty, Michael S. Diamond, and et al
The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones, Shinya Sato, Rikard Frederiksen, M. Carter Cornwall, and Vladimir J. Kefalov
The role of cDC1s in vivo: CD8 T cell priming through cross-presentation [version 1; referees: 3 approved], Derek Theisen and Kenneth Murphy
The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis, Zerina Hodzic, Alexa M. Bolock, and Misty Good
The role of psychometrics in individual differences research in cognition: A case study of the AX-CPT, Shelly R. Cooper, Corentin Gonthier, Deanna M. Barch, and Todd S. Braver
The role of retinol dehydrogenase 10 in the cone visual cycle, Yunlu Xue, Shinya Sato, David Razafsky, Bhubanananda Sahu, Susan Q. Shen, Chloe Potter, Lisa L. Sandell, Joseph C. Corbo, Krzysztof Palczewski, Akiko Maeda, Didier Hodzic, and Vladimir J. Kefalov
The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans, Lloyd S. Robinson, Warren G. Lewis, and Amanda L. Lewis
The state of neurocritical care fellowship training and attitudes toward accreditation and certification: A survey of neurocritical care fellowship program directors, Rajat Dhar, Venkatakrishna Rajajee, Anna Finley Caulfield, Matthew B. Maas, Michael L. James, Avinash Bhargava Kumar, Stephen A. Figueroa, David McDonagh, and Agnieszka Ardelt
The Surgical Infection Society revised guidelines on the management of intra-abdominal infection, John E. Mazuski, Jeffrey M. Tessier, Addison K. May, Robert G. Sawyer, Evan P. Nadler, Matthew R. Rosengart, Phillip K. Chang, Patrick J. O'Neill, Kevin P. Mollen, Jared M. Huston, Jose J. Diaz Jr, and Jose M. Prince
The SWI/SNF protein PBRM1 restrains VHL-loss-driven clear cell renal cell carcinoma, James J. Hsieh and et al
The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer, Yassar M. Hashim, Suwanna Vangveravong, Narendra V. Sankpal, Pratibha S. Binder, Jingxia Liu, S. Peter Goedegebuure, Robert H. Mach, Dirk Spitzer, and William G. Hawkins
The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help, Takeshi Inoue, Ryo Shinnakasu, Wataru Ise, Chie Kawai, Takeshi Egawa, and Tomohiro Kurosaki
The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits, Ramon A. Lorca, Xiaofeng Ma, and Sarah K. England
The use of thrombolytics in the management of complex pleural fluid collections, Jessica Heimes, Hannah Copeland, Aditya Lulla, Marjulin Duldulao, Khaled Bahjri, Salman Zaheer, and Jason M. Wallen
Thirty-day readmissions in hospitalized patients who received bezlotoxumab with antibacterial drug treatment for Clostridium difficile infection, Vimalanand S. Prabhu, Oliver A. Cornely, Yoav Golan, Erik R. Dubberke, Sebastian M. Heimann, Mary E. Hansen, Jane Liao, Alison Pedley, Mary Beth Dorr, and Stephen Marcella
Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel, Yu Zhou, Huanghe Yang, Jianmin Cui, and Christopher J. Lingle
TicTimer software for measuring tic suppression [version 2; referees: 2 approved], Jonathan K. Black, Jonathan M. Koller, and Kevin J. Black
Time course of the effects of lisdexamfetamine dimesylate in two phase 3, randomized, double‐blind, placebo‐controlled trials in adults with binge‐eating disorder, Susan L. McElroy, James I. Hudson, Maria Gasior, Barry K. Herman, Jana Radewonuk, Denise Wilfley, and Joan Busner
Time to treatment and mortality during mandated emergency care for sepsis, Christopher W. Seymour, Foster Gesten, Hallie C. Prescott, Marcus E. Friedrich, Theodore J. Iwashyna, Gary S. Phillips, Stanley Lemeshow, Tiffany Osborn, Kathleen M. Terry, and Mitchell M. Levy
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation, Jia Zhou, Renee L. Sears, Xiaoyun Xing, Bo Zhang, Daofeng Li, Nicole B. Rockweiler, Hyo Sik Jang, Mayank N.K. Choudhary, Hyung Joo Lee, Rebecca F. Lowdon, Jason Arand, Brianne Tabers, C. Charles Gu, Theodore J. Cicero, and Ting Wang
Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion, Priya Luthra, Sebastian Aguirre, Benjamin C. Yen, Colette A. Pietzsch, Maria T. Sanchez-Aparicio, Bersabeh Tigabu, Lorraine K. Morlock, Adolfo Garcia-Sastre, Daisy W. Leung, Noelle S. Williams, Ana Fernandez-Sesma, Alexander Bukreyev, and Christopher F. Basler
Topological organization of whole-brain white matter in HIV infection, Laurie M. Baker, Sarah A. Cooley, Ryan P. Cabeen, David H. Laidlaw, John A. Joska, Jacqueline Hoare, Dan J. Stein, Jodi M. Heaps-Woodruff, Lauren E. Salminen, and Robert H. Paul
Tourette syndrome research highlights from 2016 [version 1; referees: 3 approved, 1 approved with reservations], Kevin J. Black
Toxoplasma effectors targeting host signaling and transcription, Mohamed-Ali Hakimi, Philipp Olias, and L. David Sibley
Transcriptomic analysis of ribosome-bound mRNA in cortical neurites in vivo, Rebecca Ouwenga, Allison M. Lake, David O'Brien, Amit Mogha, Adish Dani, and Joseph D. Doughterty
Transethnic genome-wide scan identifies novel Alzheimer's disease loci, Carlos Cruchaga and et al
Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease, Nicole M. Gilbert, Valerie P. O'Brien, and Amanda L. Lewis
Translation efficiency is a determinant of the magnitude of miRNA-mediated repression, Kyle A. Cottrell, Pawel Szczesny, and Sergej Djuranovic
Transmesenteric robot-assisted pyeloplasty for ureteropelvic junction obstruction in horseshoe kidney, Aaron M. Potretzke, Anand Mohapatra, Jeffrey A. Larson, and Brian M. Benway
Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database, Gregory Vlacich, Pamela P. Samson, Stephanie M. Perkins, Michael C. Roach, Parag J. Parikh, Jeffrey D. Bradley, A. Craig Lockhart, Varun Puri, Bryan F. Meyers, Benjamin Kozower, and Cliff G. Robinson
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy, Cheryl E. G. Leyns, Jason D. Ulrich, Mary B. Finn, Floy R. Stewart, Lauren J. Koscal, Javier Remolina Serrano, Grace O. Robinson, Elise Anderson, Marco Colonna, and David M. Holtzmann
Trends in the management of small renal masses: A survey of members of the Endourological Society, Anand Mohapatra, Aaron M. Potretzke, John Weaver, Barrett G. Anderson, Joel Vetter, and Robert S. Figenshau
Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen, Felipe H. Santiago-Tirado, Michael D. Onken, John A. Cooper, Robyn S. Klein, and Tamara L. Doering
TRPC3 is dispensable for β-alanine triggered acute itch, Peter Dong, Changxiong Guo, Shengxiang Huang, Minghong Ma, Qin Liu, and Wenqin Luo
Tsetse fly (Glossina pallidipes) midgut responses to Trypanosoma brucei challenge, Rosemary Bateta, Jingwen Wang, Yineng Wu, Brian L. Weiss, Wesley C. Warren, Grace A. Murilla, Serap Aksoy, and Paul O. Mireji
Tumor diversity and evolution revealed through RADseq, Elizabeth B. Perry, Alvin Makohon-Moore, Caihong Zheng, Charles K. Kaufman, Jun Cai, Christine A. Iacobuzio-Donahue, and Richard M. White
Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients, Nicholas Rensing, David H. Gutmann, Michael Wong, and et al
Two-and-a-half-year clinical experience with the world's first magnetic resonance image guided radiation therapy system, Benjamin W. Fischer-Valuck, Lauren Henke, Olga Green, Rojano Kashani, Sahaja Acharya, Jeffrey D. Bradley, Clifford G. Robinson, Maria Thomas, Imran Zoberi, Wade Thorstad, Hiram Gay, Jiayi Huang, Michael Roach, Vivian Rodriguez, Lakshmi Santanam, Harold Li, Hua Li, Jessika Contreras, Thomas Mazur, Dennis Hallahan, Jeffrey R. Olsen, Parag Parikh, Sasa Mutic, and Jeff Michalski
Two distinct myeloid subsets at the term human fetal–maternal interface, Maria Laura Costa, Michelle L. Robinette, Mattia Bugatti, Mark S. Longtine, Bryanne N. Colvin, Erica Lantelme, William Vermi, Marco Colonna, D. Michael Nelson, and Marina Cella
Two forms of death in ageing Caenorhabditis elegans, Yuan Zhao, Ann F. Gilliat, Matthias Ziehm, Mark Turmaine, Hongyuan Wang, Marina Ezcurra, Chenhao Yang, George Phillips, David McBay, William B. Zhang, Linda Partridge, Zachary Pincus, and David Gems
Two sisters with Mayer-Rokitansky-Küster-Hauser syndrome and serous adenocarcinoma of the ovary, Sarah P. Huepenbecker, Laura Divine, Christina S. Chu, and David G. Mutch
Ultrastructural characterization of the glomerulopathy in alport mice by helium ion scanning microscopy (HIM), Kenji Tsuji, Hani Suleiman, Jeffrey H. Miner, James M. Daley, Diane E. Capen, Teodor G. Paunescu, and Hua A. Jenny Lu
Ultrastructure and localization of Neorickettsia in adult digenean trematodes provides novel insights into helminth-endobacteria interaction, Kerstin Fischer, Vasyl V. Tkach, Kurt C. Curtis, and Peter U. Fischer
Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues, Bo Zhang, Pamela Madden, Junchen Gu, Xiaoyun Xing, Savita Sankar, Jennifer Flynn, Kristen Kroll, and Ting Wang
Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice, Joohyun Lim, Joseph Burclaff, Guangxu He, Jason C. Mills, and Fanxin Long
Updated nomenclature for human and mouse neurofibromatosis type 1 genes, Corina Anastasaki, Lu Q. Le, Robert A. Kesterson, and David H. Gutmann
Use of a novel portable three-dimensional imaging system to measure limb volume and circumference in patients with filarial lymphedema, Channa Yahathugoda, Michael J. Weiler, Ramakrishna Rao, Lalindi De Silva, J. Brandon Dixon, Mirani V. Weerasooriya, Gary J. Weil, and Philip J. Budge
Use of low-dose computed tomography to assess pulmonary tuberculosis among healthcare workers in a tuberculosis hospital, Wei He, Bu-Dong Chen, Yan Lv, Zhen Zhou, Jin-Ping Xu, Ping-Xin Lv, Xin-Hua Zhou, Feng-Gang Ning, Cheng-Hai Li, Dong-Po Wang, and Jie Zheng
Use of the instantaneous wave-free ratio or fractional flow reserve in PCI, J. Singh and et al
Using clinical scenarios to understand preventability of Clostridium difficile infections by inpatient antibiotic stewardship programs, Jessica Seidelman, Kristen V. Dicks, Michael J. Durkin, Arthur W. Baker, Rebekah W. Moehring, Deverick J. Anderson, Daniel J. Sexton, Luke F. Chen, and Sarah S. Lewis
Vaccination with recombinant Cryptococcus proteins in glucan particles protects mice against cryptococcosis in a manner dependent upon mouse strain and cryptococcal species, Jennifer K. Lodge and et al
Validation of ICD-9-CM diagnosis codes for surgical site infection and noninfectious wound complications after mastectomy, Margaret A. Olsen, Kelly E. Ball, Katelin B. Nickel, Anna E. Wallace, and Victoria J. Fraser
Validation of preoperative variables and stratification of patients to help predict benefit of cytoreductive nephrectomy in the targeted therapy ERA, Brandon J. Manley, Eric H. Kim, Joel M. Vetter, Aaron M. Potretzke, and Seth A. Strope
Variability in antifungal and antiviral use in hospitalized children, Jennifer L. Goldman, Rachael K. Ross, Brian R. Lee, Jason G. Newland, Adam L. Hersh, Matthew P. Kronman, and Jeffrey S. Gerber
Variable step size methods for solving simultaneous algebraic reconstruction technique (SART)-type CBCT reconstructions, Heui Chang Lee, Bongyong Song, Jin Sung Kim, James J. Jung, H. Harold Li, Sasa Mutic, and Justin C. Park
Venous thromboembolism related to cytomegalovirus infection: A case report and literature review, Amar H. Kelkar, Kavitha S. Jacob, Eman B. Yousif, and John J. Farrell
Viability and tissue quality of cartilage flaps from patients with femoroacetabular hip impingement: A matched-control comparison, Francisco Rodriguez-Fontan, Karin A. Payne, Jorge Chahla, Omer Mei-Dan, Abigail Richards, Soshi Uchida, and Cecilia Pascual-Garrido
Viral RNA at two stages of reovirus infection is required for the induction of necroptosis, Angela K. Berger, Bradley E. Hiller, Deepti Thete, Anthony J. Snyder, Encarnacion Perez Jr, Jason W. Upton, and Pranav Danthi
