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Submissions from 2016

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The basal bodies of Chlamydomonas reinhardtii, Susan Dutcher and Eileen T. O'Toole

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The Brief Case: A reactive HIV rapid antibody test in a pregnant woman, Melanie L. Yarbrough and Neil W. Anderson

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The Brief Case: Dyspnea in a profoundly immunocompromised man, Andrej Spec, Carlos A.Q. Santos, and Morgan A. Pence

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The burden of Clostridium difficile infection: Estimates of the incidence of CDI from U.S. Administrative databases, Margaret A. Olsen, Yinong Young-Xu, Dustin Stwalley, Ciaran P. Kelly, Dale N. Gerding, Mohammed J. Saeed, Cedric Mahe, and Erik R. Dubberke

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The catabolite repressor protein-cyclic AMP complex regulates csgD and biofilm formation in uropathogenic Escherichia coli, David A. Hufnagel, Margery L. Evans, Sarah E. Greene, Jerome S. Pinkner, Scott J. Hultgren, and Matthew R. Chapman

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The clinical outcome study for dysferlinopathy: An international multicenter study, Matthew Harms, Alan Pestronk, and et al.

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The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1, Leonid P. Shutov, Charles A. Warwick, Xiaoyu Shi, Aswini Gnanasekaran, Andrew J. Shepherd, Durga P. Mohapatra, Trent M. Woodruff, J. David Clark, and Yuriy M. Usachev

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The contribution of GWAS loci in familial dyslipidemias, Richard K. Wilson and et al.

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The dimeric architecture of checkpoint Mec1ATR and Tel1ATM reveal a common structural organization, Marta Sawicka, Paulina H. Wanrooij, Vidya C. Darbari, Elias Tannous, Sarem Hailemariam, Daniel Bose, Alena V. Makarova, Peter M. Burgers, and Xiaodong Zhang

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The effect of chloroquine on immune activation and interferon signatures associated with HIV-1, David Clifford and et al

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The effect of dopaminergic medication on beat-based auditory timing in Parkinson’s disease, Daniel J. Cameron, Kristen A. Pickett, Gammon M. Earhart, and Jessica A. Grahn

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The effect of mesenchymal stromal cell sheets on the inflammatory stage of flexor tendon healing, Hua Shen, Ioannis Kormpakis, Necat Havlioglu, Stephen W. Linderman, Shelly E. Sakiyama-Elbert, Isaac E. Erickson, Thomas Zarembinski, Matthew J. Silva, Richard H. Gelberman, and Stavros Thomopoulos

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The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation, Amy Langdon, Nathan Crook, and Gautam Dantas

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The effects of auditory contrast tuning upon speech intelligibility, Nathan J. Killian, Paul V. Watkins, Lisa S. Davidson, and Dennis L. Barbour

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The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice, Molly Stanley, Shannon L. Macauley, Emily E. Caesar, Lauren J. Koscal, Will Moritz, Grace O. Robinson, Joseph Roh, Jennifer Keyser, Hong Jiang, and David M. Holtzman

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The effects of sun exposure on carotenoid accumulation and oxidative stress in the retina of the House Finch (Haemorhous mexicanus), Matthew B. Toomey and Kevin J. McGraw

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The evolving role of clinical registries: Existing practices and opportunities for orthopaedic surgeons, Christopher J. Dy, David B. Bumpass, Eric C. Makhni, and Kevin J. Bozic

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The fallacy of univariate solutions to complex systems problems, Christina N. Lessov-Schlaggar, Joshua B. Rubin, and Bradley L. Schlaggar

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The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy, Nigel J. Cairns and et al

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The genetic and environmental structure of the character sub-scales of the temperament and character inventory in adolescence, Nigel Lester, Danilo Garcia, Sebastian Lundstrom, Sven Brandstrom, Maria Rastam, Nora Kerekes, Thomas Nilsson, C. Robert Cloninger, and Henrik Anckarsater

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The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates, Junfei Wei, Ashish Damania, Xin Gao, Zhuyun Liu, Rojelio Mejia, Makedonka Mitreva, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez, and Bin Zhan

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The human experience with intravenous levodopa, Shan H. Siddiqi, Natalia K. Abraham, Christopher L. Geiger, Morvarid Karimi, Joel S. Perlmutter, and Kevin J. Black

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The impact of nighttime intensivists on medical intensive care unit infection-related indicators, Abhaya Trivedi, Kathleen M. McMullen, Hilary M. Babcock, and Marin H. Kollef

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The influence of temperament and character profiles on specialty choice and well-being in medical residents, Martin Sievert, Igor Zwir, Kevin M. Cloninger, Nigel Lester, Sandor Rozsa, and C. Robert Cloninger

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The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses, Subhajit Poddar, Jennifer L. Hyde, Matthew J. Gorman, Michael Farzan, and Michael S. Diamond

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The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis, Matthew J. Gorman, Subhajit Poddar, Michael Farzan, and Michael S. Diamond

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The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders, Toni Pearson and et al

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The mechanism of a formaldehyde-sensing transcriptional regulator, Katie J. Denby, Jeffrey Iwig, Claudine Bisson, Jodie Westwood, Matthew D. Rolfe, Svetlana E. Sedelnikova, Khadine Higgins, Michael J. Maroney, Patrick J. Baker, Peter T. Chivers, and Jeffrey Green

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The miR-17∼92 microRNA cluster Is a global regulator of tumor metabolism, Said Izreig, Bozena Samborska, Radia M. Johnson, Alexey Sergushichev, Eric H. Ma, Carine Lussier, Ekaterina Loginicheva, Ariel O. Donayo, Maya C. Poffenberger, Selena M. Sagan, Emma E. Vincent, Maxim N. Artyomov, Thomas F. Duchaine, and Russel G. Jones

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The Musashi 1 controls the splicing of photoreceptor-specific exons in the vertebrate retina, Daniel Murphy, Benjamin Cieply, Russ Carstens, Visvanathan Ramamurthy, and Peter Stoilov

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The myocardial and coronary histopathology and pathogenesis of hypoplastic left heart syndrome, Charles R. Cole and Pirooz Eghtesady

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The Na+/Ca2+, K+ exchanger 2 modulates mammalian cone phototransduction, Keisuke Sakurai, Frans Vinberg, Tian Wang, Jeannie Chen, and Vladimir J. Kefalov

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The NADase-negative variant of the Streptococcus pyogenes toxin NAD+ glycohydrolase induces JNK1-mediated programmed cellular necrosis, Sukantha Chandrasekaran and Michael G. Caparon

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The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control, Shin-ichiro Imai

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The network for intracortical communication in mouse visual cortex, Andreas Burkhalter

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The Non-Coding RNA Ontology (NCRO): A comprehensive resource for the unification of non-coding RNA biology, Xiaowei Wang and et al

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The O-antigen flippase Wzk can substitute for MurJ in peptidoglycan synthesis in Helicobacter pylori and Escherichia coli, Wael Elhenawy, Rebecca M. Davis, Jutta Fero, Nina R. Salama, Mario F. Felman, and Natividad Ruiz

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The pathogenesis of nonalcoholic fatty liver disease: Interplay between diet, gut microbiota, and genetic background, Jinsheng Yu, Sharon Marsh, Junbo Hu, Wenke Feng, and Chaodong Wu

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The pathogenesis of resection-associated intestinal adaptation, Brad W. Warner

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The PULSE Vision & Change Rubrics,version 1.0: A valid and equitable tool to measure transformation of life sciences departments at all institution types, Kathryn G. Miller and et al

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The relationship between age at first birth and mother's lifetime earnings: Evidence from Danish data, Man Yee Mallory Leung, Fane Groes, and Raul Santaeulalia-Llopis

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The RNA binding specificity of human APOBEC3 proteins resembles that of HIV-1 nucleocapsid, Ashley York, Sebla B. Kutluay, Manel Errando, and Paul D. Bieniasz

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The role of researchers in disseminating evidence to public health practice settings: A cross-sectional study, Allese B. McVay, Katherine A. Stamatakis, Julie A. Jacobs, Rachel G. Tabak, and Ross C. Brownson

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The role of toll-like receptors in hematopoietic malignancies, Darlene A. Monlish, Sima T. Bhatt, and Laura G. Schuettpelz

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The roles of CD137 signaling in atherosclerosis, In-Hyuk Jung and Goo Taeg Oh

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The significant impact of education, poverty, and race on Internet-based research participant engagement, Sarah M. Hartz, Tiffany Quan, Abiye Ibiebele, Sherri L. Fisher, Emily Olfson, Patricia Salyer, and Laura J. Bierut

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The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia, Brad S. Kahl and et al

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The targetable epigenetic tumor protein EZH2 is enriched in intraocular medulloepithelioma, Sarah E. Avedschmidt, Anna M. Stagner, Ralph C. Eagle Jr., George J. Harocopos, Yali Dou, and Rajesh C. Rao

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The two sides of sensory–cognitive interactions: Effects of age, hearing acuity, and working memory span on sentence comprehension, Renee DeCaro, Jonathan E. Peelle, Murray Grossman, and Arthur Wingfield

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The typical presentation spectrum of deep vein thrombosis associated with inferior vena cava malformations, Agostino Pozzi, Mustapha A. El Lakis, Jad Chamieh, Beatriz Barbera Carbonell, and Fabio Villa

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The UbiI (VisC) aerobic ubiquinone synthase is required for expression of type 1 pili, biofilm formation, and pathogenesis in uropathogenic Escherichia coli, Kyle A. Floyd, Courtney A. Mitchell, Allison R. Eberly, Spencer J. Colling, Ellisa W. Zhang, William DePas, Matthew R. Chapman, Matthew Conover, Bridget R. Rogers, Scott J. Hultgren, and Maria Hadjifrangiskou

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The use of pulmonary artery catheter in sepsis patients: A literature review, Dimitrios Velissaris, Vasilios Karamouzos, Ioanna Kotroni, Charalampos Pierrakos, and Menelaos Karanikolas

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The value of early and comprehensive diagnoses in a human fetus with hydrocephalus and progressive obliteration of the aqueduct of Sylvius: Case Report, Eduardo Ortega, Rosa I. Munoz, Nelly Luza, Francisco Geurra, Monserrat Guerra, Karin Vio, Roberto Henzi, Jaime Jaque, Sara Rodriguez, James P. McAllister, and Esteban Rodriguez

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The variance shared across forms of childhood trauma is strongly associated with liability for psychiatric and substance use disorders, Sean Kristjansson, Vivia V. McCutcheon, Arpana Agrawal, Michael T. Lynskey, Elizabeth Conroy, Dixie J. Statham, Pamela A.F. Madden, Anjali K. Henders, Alexandre A. Todorov, Kathleen K. Bucholz, Louisa Degenhardt, Nicholas G. Martin, Andrew C. Heath, and Elliot C. Nelson

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The yersiniabactin-associated ATP binding cassette proteins YbtP and YbtQ enhance Escherichia coli fitness during high-titer cystitis, Eun-Ik Koh, Chia S. Hung, and Jeffrey P. Henderson

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The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states, M. J. Toneff, A. Sreekumar, A. Tinnirello, P. Den Hollander, S. Habib, Shunqiang Li, M. J. Ellis, L. Xin, S. A. Mani, and J. M. Rosen

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Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury, Michael J. Randles, Sophie Collinson, Tobias Starborg, Aleksandr Mironov, Mira Krendel, Eva Königshausen, Lorenz Sellin, Ian S. D. Roberts, Karl E. Kadler, Rachel Lennon, and Jeffrey H. Miner

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Three-versus two-dimensional sonographic biometry for predicting birth weight and macrosomia in diabetic pregnancies, Methodius G. Tuuli, Kristen Kapalka, George A. Macones, and Alison G. Cahill

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Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis, Shadmehr Demehri, Trevor J. Cunningham, Sindhu Manivasagam, Kenneth H. Ngo, Sara Moradi Tuchayi, Rasikia Reddy, Melissa A. Meyers, David G. DeNardo, and Wayne M. Yokoyama

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TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells, James E. Ussher, Bonnie van Wilgenburg, Rachel F. Hannaway, Kerstin Ruustal, Prabhjeet Phalora, Ayako Kurioka, Ted H. Hansen, Christian B. Willberg, Rodney E. Phillips, and Paul Klenerman

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Topical decolonization does not eradicate the skin microbiota of community-dwelling or hospitalized adults, Carey-Ann D. Burnham, Patrick G. Hogan, Meghan A. Wallace, Elena Deych, William Shannon, David K. Warren, and Stephanie A. Fritz

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Tourette syndrome research highlights 2015 [version 1; referees: 3 approved], Cheryl A. Richards and Kevin J. Black

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TP53 and decitabine in acute myeloid leukemia and myelodysplastic syndromes, A. A. Petti, C. A. Miller, C. C. Fronick, M. O'Laughlin, R. S. Fulton, R. K. Wilson, L. D. Wartman, T. J. Ley, and et al

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TPL-2 regulates macrophage lipid metabolism and M2 differentiation to control TH2-mediated immunopathology, Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J. Entwistle, Hania Khoury, Stamatia Papoutsopoulou, Radma Mahmood, Nuha R. Mansour, Stanley Ching-Cheng Huang, Edward J. Pearce, Luiz Pedro S. de Carvalho, Steven C. Ley, and Mark S. Wilson

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Training the next generation of biomedical investigators in glycosciences, Stuart Kornfeld and et al

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Trajectories of depressive symptoms after hip fracture, P. Cristancho, E. J. Lenze, M. S. Avidan, and K. S. Rawson

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Transcription start site scanning and the requirement for ATP during transcription initiation by RNA polymerase II, James Fishburn, Eric Galburt, and Steven Hahn

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Transcriptome analysis of chemically-induced sensory neuron ablation in zebrafish, Jane A. Cox, Bo Zhang, Holly M. Pope, and Mark M. Voight

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Transgenic soybean production of bioactive human epidermal growth factor (EGF), Yonghua He, Monica A. Schmidt, Christopher Erwin, Jun Guo, Raphael Sun, Ken Pendarvis, Brad W. Warner, and Eliot M. Herman

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Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models, Felipe A. Navarrete, Antonio Alvau, Hoi Chang Lee, Lonny R. Levin, Jochen Buck, Patritica Martin-De Leon, Celia M. Santi, Dario Krapf, Jesse Mager, Rafael A. Fissore, Ana M. Salicioni, Alberto Darszon, and Pablo E. Visconti

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Transmission of Staphylococcus aureus from humans to green monkeys in the Gambia as revealed by whole-genome sequencing, George Weinstock and et al

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Treatment with Tumor-Treating Fields therapy and pulse dose bevacizumab in patients with bevacizumab-refractory recurrent glioblastoma: A case series., George Ansstas and David D. Tran

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TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques, Yaming Wang, Tyler K. Ulland, Jason D. Ulrich, Wilbur Song, Thomas E. Mahan, Yang Shi, Susan Gilfillan, Marina Cella, John R. Cirrito, David M. Holtzman, Marco Colonna, and et al

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Triggering receptor expressed on myeloid cells (TREM)-2 Impairs host defense in experimental melioidosis, Tassili A. F. Weehuizen, Tijmen J. Hommes, Jacqueline M. Lankelma, Hanna K. de Jong, Joris J. T. H. Roelofs, Alex F. de Vos, Marco Colonna, Tom van der Poll, and W. Joost Wiersinga

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Truncating prolactin receptor mutations promote tumor growth in murine estrogen receptor-alpha mammary carcinomas, Obi L. Griffith, Szeman Ruby Chan, Malachi Griffith, Kilannin Krysiak, Zachary L. Skidmore, Jasreet Hundal, Julie A. Allen, Cora D. Arthur, Daniele Runci, Mattia Bugatti, Alexander P. Miceli, Heather Schmidt, Lee Trani, Krishna-Latha Kanchi, Christopher A. Miller, David E. Larson, Robert S. Fulton, William Vermi, Richard K. Wilson, Robert D. Schreiber, and Elaine R. Mardis

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Tubular overexpression of Angiopoietin-1 attenuates renal fibrosis, Sudhir Singh, Scott R. Manson, Heedoo Lee, Yeawon Kim, Tuoen Liu, Qiusha Guo, Julio J. Geminiani, Paul F. Austin, and Ying Maggie Chen

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Tumor evolution in two patients with basallike breast cancer: A retrospective genomics study of multiple metastases, Katherine A. Hoadley, Marni B. Siegel, Krishna L. Kanchi, Christopher A. Miller, Li Ding, Wei Zhao, Xiaping He, Joel S. Parker, Michael C. Wendl, Robert S. Fulton, Ryan T. Demeter, Richard K. Wilson, Lisa A. Carey, Charles M. Perou, and Elaine R. Mardis

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Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes, Fanglin Guan, Yu Niu, Tianxiao Zhang, Songfang Liu, Lei Ma, Ting Qi, Jia Feng, Hong Zuo, Guohong Li, Xufeng Liu, and Shujin Wang

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Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population, Rui Sun, Jian-Ping Liu, Chang Gao, Ying-Ying Xiong, Min Li, Ya-Ping Wang, Yan-Wei Su, Mei Lin, An-Li Jiang, Ling-Fan Xiong, Yan Xie, and Jue-Ping Feng

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Type I interferon receptor deficiency in dendritic cells facilitates systemic murine norovirus persistence despite enhanced adaptive immunity, Timothy J. Nice, Lisa C. Osborne, Vesselin T. Tomov, David Artis, E. John Wherry, and Herbert W. Virgin

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Type I Interferon response in olfactory bulb, the site of tick-borne flavivirus accumulation, is primarily regulated by IPS-1, Chaitanya Kurhade, Loreen Zegenhagen, Elvira Weber, Sharmila Nair, Kristin Michaelson-Preusse, Julia Spanier, Nelson O. Gekara, Andrea Kroger, and Anna K. Overby

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Ultrasound modulates ion channel currents, Jan Kubanek, Jingyi Shi, Jon Marsh, Di Chen, Cheri Deng, and Jianmin Cui

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Understanding the ureter: challenges and opportunities, Alyssa Park and Ramakrishna Venkatesh

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Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses, Keith M. Jacobs, Sandeep Misri, Barbara Meyer, Suyash Raj, Cheri L. Zobel, Barry P. Sleckman, Dennis E. Hallahan, and Girdhar G. Sharma

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Urb-RIP - An adaptable and efficient approach for immunoprecipitation of RNAs and associated RNAs/proteins, Kyle A. Cottrell and Sergej Djuranovic

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Urinary metabolomics identifies a molecular correlate of interstitial cystitis/bladder pain syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort, Kaveri S. Parker, Jan R. Crowley, Alisa J. Stephens-Shields, Adrie van Bokhoven, M. Scott Lucia, H. Henry Lai, Gerald L. Andriole, Thomas M. Hooton, Chris Mullins, and Jeffrey P. Henderson

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Ursolic acid enhances macrophage autophagy and attenuates atherogenesis, Shuilong Leng, Stephen Iwanowycz, Fatma Saaoud, Junfeng Wang, Yuzhen Wang, Ismail Sergin, Babak Razani, and Daping Fan

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Use of sodium bicarbonate in cardiac arrest: Current guidelines and literature review, Dimitrios Velissaris, Vassilios Karamouzos, Charalampos Pierrakos, Ioanna Koniari, Christina Apostolopoulou, and Menelaos Karanikolas

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Using free internet videogames in upper extremity motor training for children with cerebral palsy, Marisa Sevick, Elizabeth Eklund, Allison Mensch, Matthew Foreman, John Standeven, and Jack Engsberg

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Using propensity score methods to assess causal effects of mothers' dieting behavior on daughters' early dieting behavior, Donna L. Coffman, Katherine N. Balantekin, and Jennifer S. Savage

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US intergroup study of chemotherapy plus dasatinib and allogeneic stem cell transplant in Philadelphia chromosome positive ALL, Geoffrey L. Uy

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USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response, Zhiquan Wang, Honglian Zhang, Ji Liu, Abigael Cheruiyot, Jeong-Heon Lee, Tamas Ordog, Zhenkun Lou, Zhongsheng You, and Zhiguo Zhang

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Utility of Washington Early Recognition Center self-report screening questionnaires in the assessment of patients with schizophrenia and bipolar disorder, Christina J. Hsieh, Douglass Godwin, and Daniel Mamah

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Utilization trends of pedicle subtraction osteotomies compared to posterior spinal fusion for deformity: A national database analysis between 2008–2011, Jeffrey L. Gum, Leah Y. Carreon, Jacob M. Buchowski, Lawrence G. Lenke, and Steven D. Glassman

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Variation in practice regarding pretreatment with dual antiplatelet therapy for patients with non–ST elevation myocardial infarction, Ali Shafiq, Javier Valle, Jae-Sik Jang, Mohammed Qintar, Kensey Gosch, David J. Cohen, Mandeep Singh, Richard Bach, and John A. Spertus

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Video capsule endoscopy in left ventricular assist device recipients with obscure gastrointestinal bleeding, Surachai Amornsawadwattana, Michael Nassif, David Raymer, Shane LaRue, and Chien-Huan Chen

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VISIT-TS: A multimedia tool for population studies on tic disorder, M. Jonathan Vachon, Catherine Woodstock Striley, Mollie R. Gordon, Miriam L. Schroeder, Emily C. Bihun, Jonathan M. Koller, and Kevin J. Black

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Visualizing tumor evolution with the fishplot package for R, Christopher A. Miller, Joshua McMichael, Ha X. Dang, Christopher A. Maher, Li Ding, Timothy J. Ley, Elaine R. Mardis, and Richard K. Wilson

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Vortex ring behavior provides the epigenetic blueprint for the human heart, Per M. Arvidsson, Sándor J. Kovács, Johannes Töger, Rasmus Borgquist, Einar Heiberg, Marcus Carlsson, and Håkan Arheden

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Voxel-based morphometry in individuals at genetic high risk for schizophrenia and patients with schizophrenia during their first episode of psychosis, Miao Chang, Fay Y. Womer, Chuan Bai, Qian Zhou, Shengnan Wei, Xiaowei Jiang, Haiyang Geng, Yifang Zhou, Yanqing Tang, and Fei Wang