Submissions from 2016
Neuroimaging biomarkers of a history of concussion observed in asymptomatic young athletes, Catherine A. Orr, Matthew D. Albaugh, Richard Watts, Hugh Garavan, Trevor Andrews, Joshua P. Nickerson, Jay Gonyea, Scott Hipko, Cole Zweber, Katherine Logan, and James J. Hudziak
Neuroimaging evidence of deficient axon myelination in Wolfram syndrome, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Bess A. Marshall, Kohsuke Kanekura, Fumihiko Urano, Allison N. Bischoff, Joshua S. Shimony, Tamara Hershey, and Washington University Wolfram Syndrome Research Study Group
Neuromodulation of the failing heart: Lost in translation?, Mirnela Byku and Douglas L. Mann
Neurons in the primate dorsal striatum signal the uncertainty of object–reward associations, J. Kael White and Ilya E. Monosov
Neuropathic pain: An updated grading system for research and clinical practice, Simon Haroutounian and et al
Neutrophil extracellular traps enhance early inflammatory response in Sendai virus-induced asthma phenotype, Antonina Akk, Luke E. Springer, and Christine T.N. Pham
New radiographic index for occipito-cervical instability, Moon Soo Park, Seong-Hwan Moon, Tae-Hwan Kim, Jae Keun Oh, Ji Hoon Nam, Jae Kyun Jung, and K. Daniel Riew
New systemic therapies for locally advanced and metastatic thyroid cancer, Cynthia J. Herrick and Jeffrey F. Moley
Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response, X R. Mao, D M. Kaufman, and C M. Crowder
Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice, Natalie E. de Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin-ichiro Imai, and Douglas R. Seals
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion, Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, and Jeffrey Milbrandt
Nmnat1 protects neuronal function without altering phospho-tau pathology in a mouse model of tauopathy, Erik S. Musiek, David D. Xiong, Tirth Patel, Yo Sasaki, Yinong Wang, Adam Q. Bauer, Risham Singh, Samantha L. Finn, Joseph P. Culver, Jeffrey Milbrandt, and David M. Holtzman
Nociceptive TRP channels: Sensory detectors and transducers in multiple pain pathologies, Aaron D. Mickle, Andrew J. Shepherd, and Durga P. Mohapatra
Nonalcoholic fatty liver disease: Pros and cons of histologic systems of evaluation, Elizabeth M. Brunt
Normal brain response to propofol in advance of recovery from unresponsive wakefulness syndrome, Stefanie Blain-Moraes, Rober Boshra, Heung Kan Ma, Richard Mah, Kyle Ruiter, Michael Avidan, John F. Connolly, and George A. Mashour
North Carolina macular dystrophy (MCDR1) caused by a novel tandem duplication of the PRDM13 gene, Sara J. Bowne, Lori S. Sullivan, Dianna K. Wheaton, Kirsten G. Locke, Kaylie D. Jones, Daniel C. Koboldt, Robert S. Fulton, Richard K. Wilson, Susan H. Blanton, David G. Birch, and Stephen P. Daiger
NOTCH signaling in skeletal progenitors is critical for fracture repair, Cuicui Wang, Jason A. Inzana, Anthony J. Mirando, Yinshi Ren, Zhaoyang Liu, Jie Shen, Regis J. O'Keefe, Hani A. Awad, and Matthew J. Hilton
Nurses' Health Study: Demonstrating the impact of research, and adapting new measures and approaches to increase relevance and effect of cohort studies, Graham A. Colditz
Nutritional quality and marketing strategies of fast food children’s combo meals in Guatemala, Sofia Mazariegos, Violeta Chacon, Adam Cole, and Joaquin Barnoya
OmniSearch: A semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data, Xiaowei Wang and et al
Open source drug discovery with the Malaria Box compound collection for neglected diseases and beyond, Na Le Dang, Tyler B. Hughes, Donatella Taramelli, and et al.
Opsin repertoire and expression patterns in horseshoe crabs: Evidence from the genome of limulus polyphemus (arthropoda: Chelicerata)., Wesley C. Warren, Patrick Minx, Michael J. Montague, Lucinda Fulton, Richard K. Wilson, and et al
Optimized and automated radiosynthesis of [18F]DHMT for translational imaging of reactive oxygen species with positron emission tomography, Wenjie Zhang, Zhengxin Cai, Lin Li, Jim Ropchan, Keunpoong Lim, Nabil E. Boutagy, Jing Wu, John C. Stendahl, Wenhua Chu, Robert Gropler, Albert J. Sinusas, Chi Liu, and Yiyun Huang
Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems, Gregory W. Mattingly and Richard H. Anderson
Osteotomies in the cervical spine, Venu M. Nemani, Peter B. Derman, and Han Jo Kim
Outcomes following laminoplasty or laminectomy and fusion in patients with myelopathy caused by ossification of the posterior longitudinal ligament: A systematic review, Weerasak Singhatanadgige, Worawat Limthongkul, Frank Valone III, Wicharn Yingsakmongkol, and K. Daniel Riew
Outcomes of joint preservation surgery: Comparison of patients with developmental dysplasia of the hip and femoroacetabular impingement, Etienne L. Belzile, Paul E. Beaulé, Jae-Jin Ryu, and John C. Clohisy
Oxidative DNA damage stalls the human mitochondrial replisome, Gorazd Stojkovič, Alena V. Makarova, Paulina H. Wanrooij, Josefin Forslund, Peter M. Burgers, and Sjoerd Wanrooij
p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer, Emily Powell, Jiansu Shao, Yuan Yuan, Hsiang-Chun Chen, Shirong Cai, Gloria V. Echeverria, Nipun Mistry, Keith F. Decker, Christopher Schlosberg, Kim-Anh Do, John R. Edwards, Han Liang, David Piwnica-Worms, and Helen Piwnica-Worms
Pangolin genomes and the evolution of mammalian scales and immunity, Richard K. Wilson, Wesley C. Warren, Patrick Minx, and et al
Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo, Jang-Eun Cho, Shar-yin N. Huang, Peter M. Burgers, Stewart Shuman, Yves Pommier, and Sue Jinks-Robertson
Parameterization for in-silico modeling of ion channel interactions with drugs, Jonathan D. Moreno, Timothy J. Lewis, and Colleen E. Clancy
Parcellations and connectivity patterns in human and macaque cerebral cortex, David C. Van Essen, Chad Donahue, Donna L. Dierker, and Matthew F. Glasser
Pathogenic Acinetobacter: From the cell surface to infinity and beyond, Brent S. Weber, Christian M. Harding, and Mario F. Feldman
Pathogenic Chikungunya virus evades B cell responses to establish persistence, David W. Hawman, Julie M. Fox, Alison W. Ashbrook, Nicholas A. May, Kristin M.S. Schroeder, Raul M. Torres, James E. Crowe Jr., Terence S. Dermody, Michael S. Diamond, and Thomas E. Morrison
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 1; referees: 2 approved, 2 approved with reservations], Daniel S. Ory and et al
Patient-reported outcomes of brentuximab vedotin in Hodgkin lymphoma and anaplastic large-cell lymphoma, Robert Chen, Suzanne Allibone, Nancy L. Bartlett, Pauline Brice, Andy Chen, Katrina Pose, Lynn Rich, Vijay Bonthapally, Phillip M. Garfin, and Michelle Fanale
Patterns of genome-wide variation in Glossina fuscipes fuscipes tsetse flies from Uganda, Andrea Gloria-Soria, W. Augustine Dunn, Erich L. Telleria, Benjamin R. Evans, Loyce Okedi, Richard Echodu, Wesley C. Warren, Michael J. Montague, Serap Aksoy, and Adalgisa Caccone
PER1 rs3027172 genotype interacts with early life stress to predict problematic alcohol use, but not reward-related ventral striatum activity, David A.A. Baranger, Chloe Ifrah, Aric A. Prather, Caitlin E. Carey, Nadia S. Corral-Frias, Emily Drabant Conley, Ahmad R. Hariri, and Ryan Bogdan
Percutaneous pulmonary valve implantation alters electrophysiologic substrate, Hoang H. Nguyen, Shabana Shahanavaz, George F. Van Hare, David T. Balzer, Ramzi Nicolas, and Jennifer N. Avari Silva
Performance metrics in professional baseball pitchers before and after surgical treatment for neurogenic thoracic outlet syndrome, Robert W. Thompson, Corey Dawkins, Chandu Vemuri, Michael W. Mulholland, Tyler D. Hadzinsky, and Gregory J. Pearl
Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusions, Oliver Karam, Pierre Demaret, Alain Duhamel, Alison Shefler, Philip C. Spinella, Simon J. Stanworth, Marisa Tucci, Stephane Leteurtre, and for the PlasmaTV investigators
Personality polygenes, positive affect, and life satisfaction, Andrew C. Heath and et al
Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei, Natalie R. Lazar Adler, Elizabeth M. Allwood, Deanna Deveson Lucas, Paul Harrison, Stephen Watts, Alexandra Dimitropoulos, Puthayalai Treerat, Priyangi Alwis, Rodney J. Devenish, Mark Prescott, Brenda Govan, Ben Adler, Marina Harper, and John D. Boyce
PET imaging of in vivo caspase-3/7 activity following myocardial ischemia-reperfusion injury with the radiolabeled isatin sulfonamide analogue [(18)F]WC-4-116, Arun K. Thukkani, Kooresh I. Shoghi, Dong Zhou, Jinbin Xu, Wenhua Chu, Eric Novak, Delphine L. Chen, Robert J. Gropler, and Robert H. Mach
Pharmacokinetics and safety of elotuzumab combined with lenalidomide and dexamethasone in patients with multiple myeloma and various levels of renal impairment: Results of a phase Ib study, Jesus Berdeja, Sundar Jagannath, Jeffrey Zonder, Ashraf Badros, Jonathan L. Kaufman, Robert Manges, Manish Gupta, Amol Tendolkar, Mark Lynch, Eric Bleickardt, Prashni Paliwal, and Ravi Vij
Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo, See-Hyoung Park, Young Min Chung, Jessica Ma, Qin Yang, Jonathan S. Berek, and Mickey C-T Hu
Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy, Haeseong Park and et al
Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ, Katrina N. Koc, Saurabh P. Singh, Joseph L. Stodola, Peter M. Burgers, and Roberto Galletto
Pilot clinical observations between food and drug seeking derived from fifty cases attending an eating disorder clinic, Harriet Beitscher-Campbell, Kenneth Blum, Marcelo Febo, Margaret A. Madigan, John Giordano, Rajendra D. Badgaiyan, Eric R. Braverman, Kristina Dushaj, Mona Li, and Mark S. Gold
Plasmodium falciparum histidine-rich protein II compromises brain endothelial barriers and may promote cerebral malaria pathogenesis, Priya Pal, Brian P. Daniels, Anna Oskman, Michael S. Diamond, Robyn S. Klein, and Daniel E. Goldberg
Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome, Andrew P. Groves, Patrick Reich, Binayak Sigdel, and T. Keefe Davis
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)*, Jason W. Ashley, William D. Hancock, Alexander J. Nelson, Robert N. Bone, Hubert M. Tse, Mary Wohltmann, John Turk, and Sasanka Ramanadham
Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation, C Wang, C Qu, Y Alippe, S L. Bonar, R Civitelli, Y Abu-Amer, M O. Hottiger, and G Mbalaviele
Polyglycine acts as a rejection signal for protein transport at the chloroplast envelope, Joshua K. Endow, Agostinho Gomes Rocha, Amy J. Baldwin, Rebecca L. Roston, Toshio Yamaguchi, Hironari Kamikubo, and Kentaro Inoue
Polyunsaturated fatty acids and prostate cancer risk: A Mendelian randomisation analysis from the PRACTICAL consortium, Adam S. Kibel and et al
Postinflammatory hyperpigmentation after human cold pain testing, Melissa J. Wolz, Katelyn E. Sadler, Caela C. Long, Daniel S. Brenner, Brian S. Kim, Robert W. Gereau IV, and Benedict J. Kolber
Postoperative severe headache following cervical posterior surgical fixation from C2 distally, Ryoji Tauchi, Sang-Hun Lee, Jin-Young Kim, Yong-Chan Kim, Colleen Peters, Shiro Imagama, Naoki Ishiguro, Jacob Buchowski, and K. Daniel Riew
Postural stability in older adults with a distal radial fracture, Craig R. Louer, Sean L. Boone, Andre K. Guthrie, John R. Motley, Ryan P. Calfee, and Lindley B. Wall
Practical considerations for noise power spectra estimation for clinical CT scanners, Steven Dolly, Hsin-Chen Chen, Mark Anastasio, Sasa Mutic, and Hua Li
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells, Matthew E. Bechard, Eric D. Bankaitis, Susan B. Hipkens, Alessandro Ustione, David W. Piston, Yu-Ping Yang, Mark A. Magnuson, and Christopher V.E. Wright
Predicting all-cause mortality from basic physiology in the Framingham Heart Study, William B. Zhang and Zachary Pincus
Predictors and outcomes of crossover to surgery from physical therapy for meniscal tear and osteoarthritis a randomized trial comparing physical therapy and surgery, Jeffrey N. Katz, John Wright, Kurt P. Spindler, Lisa A. Mandl, Clare E. Safran-Norton, Emily K. Reinke, Bruce A. Levy, Rick W. Wright, Morgan H. Jones, Scott D. Martin, Robert G. Marx, and Elena Losina
Predictors of change in depressive symptoms from preschool to first grade, Trude Reinfjell, Silja Berg Kårstad, Turid Suzanne Berg-Nielsen, Joan L. Luby, and Lars Wichstrøm
Predictors of full-time faculty appointment among MD-PhD program graduates: A national cohort study, Dorothy A. Andriole and Donna B. Jeffe
Preoperative falls predict postoperative falls, functional decline, and surgical complications, Vanessa L. Kronzer, Michelle R. Jerry, Arbi Ben Abdallah, Troy S. Wildes, Susan L. Stark, Sherry L. McKinnon, Daniel L. Helsten, Anshuman Sharma, and Michael S. Avidan
Prevalence of asymptomatic bacteriuria in hospitalized patients, Sergio E. Trevino, Jeffrey P. Henderson, Jiami Wu, Candice Cass, and Jonas Marschall
Prevalence of non-febrile seizures in children with idiopathic autism spectrum disorder and their unaffected siblings: a retrospective cohort study, Lena M. McCue, Louise H. Flick, Kimberly A. Twyman, Hong Xian, and Thomas E. Conturo
Prevalence of qacA/B genes and mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) isolates in the setting of chlorhexidine bathing without mupirocin, David K. Warren, Martin Prager, Satish Munigala, Meghan A. Wallace, Colleen R. Kennedy, Kerry M. Bommarito, John E. Mazuski, and Carey-Ann D. Burnham
Preventing germ cell death by inactivating aryl hydrocarbon receptor (AHR), P Esakky and K H. Moley
Previous antibiotic exposure increases risk of infection with extended-spectrum-β-lactamase- and AmpC-producing Escherichia coli and Klebsiella pneumoniae in pediatric patients, Danielle M. Zerr, Arianna Miles-Jay, Matthew P. Kronman, Chuan Zhou, Amanda L. Adler, Wren Haaland, Scott J. Wessman, Alexis Elward, Jason G. Newland, Theoklis Zaoutis, and Xuan Qin
Prion-associated toxicity is rescued by elimination of cotranslational chaperones, Kathryn M. Keefer and Heather L. true
Professional Decision-Making in Research (PDR): The validity of a new measure, James M. DuBois, John T. Chibnall, Raymond C. Tait, Jillon S. Vander Wal, Kari A. Baldwin, Alison L. Antes, and Michael D. Mumford
Professionalism in residency training: A compilation of desirable behaviors and a case-based comparison between pathologists in training and practice, Ann M. Gronowski, Mitchell R. McGill, and Ronald E. Domen
Proficient replication of the yeast genome by a viral DNA polymerase, Joseph L. Stodola, Carrie M. Stith, and Peter M. Burgers
Prognostic microRNA signatures derived from The Cancer Genome Atlas for head and neck squamous cell carcinomas, Nathan Wong, Shariq S. Khwaja, Callie M. Baker, Hiram A. Gay, Wade L. Thorstad, Mackenzie D. Daly, James S. Lewis Jr., and Xiaowei Wang
Prognostic value of lymph node ratio in patients with pathological N1 non-small cell lung cancer: A systematic review with meta-analysis, Qian Li, Ping Zhan, Dongmei Yuan, Tangfeng Lv, Alexander Sasha Krupnick, Antonio Passaro, Alessandro Brunelli, Matthew P. Smeltzer, Raymond U. Osarogiagbon, and Yong Song
Programmatic use of molecular xenomonitoring at the level of evaluation units to assess persistence of lymphatic filariasis in Sri Lanka, Ramakrishna U. Rao, Sandhya D. Samarasekera, Kumara C. Nagodavithana, Manjula W. Punchihewa, Tharanga D. M. Dassanayaka, Gamini P. K. D, Ethan Ford, Udaya S. B. Ranasinghe, Ralph H. Henderson, and Gary J. Weil
Progressive elbow pain, Alexis Descatha, Thomas Despreaux, Ryan P. Calfee, Bradley Evanoff, and Olivier Saint-Lary
Proline absorption and SGK1 expression are inhibited in intestinal tis7 transgenic mice, Jianyun Lu, Amy M. Garcia, Taylor Geisman, Derek Wakeman, Brad W. Warner, Elzbieta A. Swietlicki, Marc S. Levin, and Deborah C. Rubin
Prospective comorbidity-matched study of Parkinson's disease and risk of mortality among women, Anke C. Winter, Pamela M. Rist, Julie E. Buring, and Tobias Kurth
Prospective evidence of a circulating microRNA signature as a non-invasive marker of hepatocellular carcinoma in HBV patients, Xiaowei Wang and et al
Prospective exploratory muscle biopsy, imaging, and functional assessment in patients with late-onset Pompe disease treated with alglucosidase alfa: The EMBASSY Study, Alan Pestronk and et al
Prostate MRI: A national survey of urologist’s attitudes and perceptions, Brandon J. Manley, John A. Brockman, Valary T. Raup, Kathryn J. Fowler, and Gerald L. Andriole
Proteomic analysis of the bovine and human ciliary zonule, Alicia De Maria, Phillip A. Wilmarth, Larry L. David, and Steven Bassnett
Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival, Laura J. Smithson and David H. Gutmann
Protocol for the Electroencephalography Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) study: A pragmatic, randomised clinical trial, T. S. Wildes, A. C. Winter, H. R. Maybrier, A. M. Mickle, E. J. Lenze, S. Stark, N. Lin, S. L. McKinnon, M. R. Muench, M. R. Murphy, R. T. Upadhyayula, B. A. Fritz, K. E. Escallier, G. P. Apakama, D. A. Emmert, T. J. Graetz, T. W. Stevens, B. J. Palanca, R. Hueneke, S. Melby, B. Torres, M. S. Avidan, and et al
Psychometric properties of the Greek TCI-R and its clinical correlates: Schizotypy and the self-regulation of affective and cognitive functioning, Stella G. Giakoumaki, Leda Karagiannopoulou, Sandor Rozsa, Chrysoula Zouraraki, Penny Karamaouna, and C. Robert Cloninger
Pten cell autonomously modulates the hematopoietic stem cell response to inflammatory cytokines, Shaina N. Porter, Andrew S. Cluster, Robert A.J. Signer, Jenna Voigtmann, Darlene A. Monlish, Laura G. Schuettpelz, and Jeffrey A. Magee
Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort, Adam S. Kibel and et al
Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system, A-Ram Lee, Kwang Woo Ko, Hojae Lee, Yi-Seul Yoon, Mi-Ryoung Song, and Chul-Seung Park
pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens, Jasreet Hundal, Beatriz M. Carreno, Allegra A. Petti, Gerald P. Linette, Obi L. Griffith, Elaine R. Mardis, and Malachi Griffith
Quantifying the Twitter influence of third party commercial entities versus healthcare providers in thirteen medical conferences from 2011 – 2013, Tejas Desai, Vibhu Dhingra, Afreen Shariff, Aabid Shariff, Edgar Lerma, Parteek Singla, Swapnil Kachare, Zoheb Syed, Deeba Minhas, Ryan Madanick, and Xiangming Fang
Quantifying transmission of clostridium difficile within and outside healthcare settings, David P. Durham, Margaret A. Olsen, Erik R. Dubberke, Alison P. Galvani, and Jeffrey P. Townsend
Quantitative amyloid imaging in autosomal dominant Alzheimer’s disease: Results from the DIAN study group, Yi Su, Tyler M. Blazey, Christopher J. Owen, Jon J. Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C. Hornbeck, Beau M. Ances, Abraham Z. Snyder, Lisa A. Cash, Eric McDade, Chengjie Xiong, Daniel S. Marcus, John C. Morris, Randall J. Bateman, Tammie L. S. Benzinger, and et al.
Quantitative analysis of high-resolution microendoscopic images for diagnosis of neoplasia in patients with Barrett’s esophagus, Dongsuk Shin, Michelle H. Lee, Alexandros D. Polydorides, Mark C. Pierce, Peter M. Vila, Neil D. Parikh, Daniel G. Rosen, Sharmila Anandasabapathy, and Rebecca R. Richards-Kortum
Quantitative autistic trait measurements index background genetic risk for ASD in Hispanic families, Joshua Page, John Nicholas Constantino, Katherine Zambrana, Eden Martin, Ilker Tunc, Yi Zhang, Anna Abbacchi, and Daniel Messinger
Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq, Yiming K. Chang, Yogesh Srivastava, Caizhen Hu, Adam Joyce, Xiaoxiao Yang, Zheng Zuo, James J. Havranek, Gary D. Stormo, and Ralf Jauch
Quantitative ultrasound assessment of Duchenne muscular dystrophy using edge detection analysis, Sisir Koppaka, Irina Sklyar, Seward B. Rutkove, Basil T. Darras, Brian W. Anthony, Craig M. Zaidman, and Jim S. Wu
Rab3-GEF controls active zone development at the Drosophila neuromuscular junction, Haneui Bae, Shirui Chen, John P. Roche, Minrong Ai, Chunlai Wu, Aaron Diantonio, and Ethan R. Graf
