Submissions from 2015
Expression quantitative trait loci information improves predictive modeling of disease relevance of non-coding genetic variation, Damien C. Croteau-Cronka, Angela J. Rogers, Towfique Raj, Michael J. McGeachie, Weiliang Qui, John P. Ziniti, Benjamin J. Stubbs, Liming Liang, Fernando D. Martinez, Robert C. Strunk, Robert F. Lemanske Jr., Andrew H. Liu, Barbara E. Stranger, Vincent J. Carey, and Benjamin A. Raby
Extending injury- and disease-resistant CNS phenotypes by repetitive epigenetic conditioning, Jeffrey M. Gidday
Extending reference assembly models, Deanna M. Church, Valerie A. Schneider, Karyn Meltz Steinberg, Michael C. Schatz, Aaron R. Quinlan, Chen-Shan Chin, Paul A. Kitts, Bronwen Aken, Gabor T. Marth, Michael M. Hoffman, Javier Herrero, M. Lisandra Zepeda Mendoza, Richard Durbin, and Paul Flicek
Extreme sensory complexity encoded in the 10-megabase draft genome sequence of the chromatically acclimating cyanobacterium Tolypothrix sp. PCC 7601, Kymberlie Hallsworth-Pepin, Aye Wollam, Sandra Clifton, and et al
Factors associated with infection following anterior cruciate ligament reconstruction, Robert H. Brophy, Rick W. Wright, Laura J. Huston, Samuel K. Nwosu, the MOON Knee Group, and Kurt P. Spindler
Familiality and SNP heritability of age at onset and episodicity in major depressive disorder, J. P. Rice and et al
Fast and efficient image reconstruction for high density diffuse optical imaging of the human brain, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani
Feasibility of a randomized clinical trial for treatment of femoroacetabular impingement of the hip, Gloria N. Boye, Kerri Murray, John C. Clohisy, and Young-Jo Kim
Fetal-to-maternal signaling to initiate parturition, Erin L. Reinl and Sarah K. England
Fibroblast growth factor 9 regulation by MicroRNAs controls lung development and links DICER1 loss to the pathogenesis of Pleuropulmonary Blastoma, Yongjun Yin, Angela M. Castro, Marrit Hoekstra, Thomas J. Yan, Ajay C. Kanakamedala, Louis P. Dehner, D. Ashley Hill, and David M. Ornitz
Fibroblast growth factor signaling in skeletal development and disease, David M. Ornitz and Pierre J. Marie
Filling in the gaps: Anticipatory control of eye movements in chronic mild traumatic brain injury, Mithun Diwakar, Deborah L. Harrington, Jun Maruta, Jamshid Ghajar, Fady El-Gabalawy, Laura Muzzatti, Maurizio Corbetta, Ming-Xiong Huang, and Roland R. Lee
First-trimester 3-dimensional power Doppler placental vascularization indices from the whole placenta versus the placental bed to predict preeclampsia: Does pregnancy-associated plasma protein A or uterine artery Doppler sonography help?, Karen E. Hannaford, Methodius Tuuli, Katherine R. Goetzinger, Linda Odibo, Alison G. Cahill, George Macones, and Anthony O. Odibo
Fmrp targets or not: Long, highly brain-expressed genes tend to be implicated in autism and brain disorders, Rebecca L. Ouwenga and Joseph Dougherty
Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies, Ying Maggie Chen and Helen Liapis
FoxP1 orchestration of ASD-relevant signaling pathways in the striatum, Daniel J. Araujo, Ashley G. Anderson, Stefano Berto, Wesley Runnels, Matthew Harper, Simon Ammanuel, Michael A. Rieger, Hung-Chung Huang, Kacey Rajkovich, Kristofer W. Loerwald, Joseph D. Dekker, Haley O. Tucker, Joseph D. Dougherty, Jay R. Gibson, and Genevieve Konopka
Fractalkine signaling regulates macrophage recruitment into the cochlea and promotes the survival of spiral ganglion neurons after selective hair cell lesion, Tejbeer Kaur, Darius Zamani, Ling Tong, Edwin W. Rubel, Kevin K. Ohlemiller, Keiko Hirose, and Mark E. Warchol
Full thickness macular hole case after intravitreal aflibercept treatment, Yuji Oshima, Rajendra S. Apte, Shintaro Nakao, Shigeo Yoshida, and Tatsuro Ishibashi
Functional characterization of bacteria isolated from ancient Arctic soil exposes diverse resistance mechanisms to modern antibiotics, Gabriel G. Perron, Lyle Whyte, Peter J. Turnbaugh, Jacqueline Goordial, William P. Hanage, Gautam Dantas, and Michael M. Desai
Functional heterogeneity in CD4+ T cell responses against a bacterial pathogen, Ashley Viehmann Milam and Paul M. Allen
Function and postnatal changes of dural afferent fibers expressing TRPM8 channels, Lynn Ren, Ajay Dhaka, and Yu-Qing Cao
GABA-A inhibition shapes the spatial and temporal response properties of Purkinje cells in the macaque cerebellum, Pablo M. Blazquez and Tatyana A. Yakusheva
GABAB encephalitis: A fifty-two-year-old man with seizures, dysautonomia, and acute heart failure, Matthew C. Loftspring, Eric Landsness, Lindsey Wooliscroft, Robert Rudock, Sally Jo, and Kevin R. Patel
Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction, Zhen Yu, Bharath Sunchu, Wilson C. Fok, Nahla Alshaikh, and Viviana I. Perez
General N-and O-linked glycosylation of lipoproteins in mycoplasmas and role of exogenous oligosaccharide, James M. Daubenspeck, David S. Jordan, Warren Simmons, Matthew B. Renfrow, and Kevin Dybvig
Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors, Peirong Hu, Yedda Li, Mark S. Sands, Thomas McCrown, and Tal Kafri
Genetically identified suppressed-by-contrast retinal ganglion cells reliably signal self-generated visual stimuli, Nai-Wen Tien, James T. Pearson, Charles R. Heller, Jay Demas, and Daniel Kerschensteiner
Genetic heterogeneity of induced pluripotent stem cells: Results from 24 clones derived from a single C57BL/6 mouse, Cheng Li, Jeffery M. Klco, Nichole M. Helton, Daniel R. George, Jacqueline L. Mudd, Christopher A. Miller, Charles Lu, Robert Fulton, Michelle O'Laughlin, Catrina Fronick, Richard K. Wilson, and Timothy J. Ley
Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker, Michael S. Behnke, Asis Khan, and David Sibley
Genetic risk for aortic aneurysm in adolescent idiopathic scoliosis, Gabe Haller, David M. Alvarado, Marcia C. Willing, Alan C. Braverman, Keith H. Bridwell, Michael Kelly, Lawrence G. Lenke, Scott J. Luhmann, Christina A. Gurnett, and Matthew B. Dobbs
Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study, Ingrid B. Borecki and et al
Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis, Xiao Xiao, Zhiguo Liu, Rui Wang, Jiayin Wang, Song Zhang, Xiqiang Cai, Kaichun Wu, Raymond C. Bergan, Li Xu, and Daiming Fan
Genome modeling system: A knowledge management platform for genomics, Malachi Griffith, Obi L. Griffith, Scott M. Smith, Avinash Ramu, Matthew B. Callaway, Anthony M. Brummett, Michael J. Kiwala, Adam C. Coffman, Allison A. Regier, Ben J. Oberkfell, Gabriel E. Sanderson, Thomas P. Mooney, Nathaniel G. Nutter, Edward A. Belter, Feiyu Du, Robert L. Long, Travis E. Abbott, Ian T. Ferguson, David L. Morton, Mark M. Burnett, James V. Weible, Joshua B. Peck, Adam Dukes, Joshua F. McMichael, Justin T. Lolofie, Brian R. Derickson, Jasreet Hundal, Zachary L. Skidmore, Benjamin J. Ainscough, Nathan D. Dees, William S. Schierding, Cyriac Kandoth, Kyung H. Kim, Charles Lu, Christopher C. Harris, Nicole Maher, Christopher A. Maher, Vincent J. Magrini, Benjamin S. Abbott, Ken Chen, Eric Clark, Indraniel Das, Xian Fan, Amy E. Hawkins, Todd G. Helper, Todd N. Wylie, Shawn M. Leonard, William E. Schroeder, Xiaoqi Shi, Lynn K. Carmichael, Matthew R. Weil, Richard W. Wohlstadter, Gary Stiehr, Michael D. McLellan, Craig S. Pohl, Christopher A. Miller, Daniel C. Koboldt, Jason R. Walker, James M. Eldred, David E. Larson, David J. Dooling, Li Ding, Elaine R. Mardis, and Richard K. Wilson
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels, Mary F. Feitosa, Kai Ye, Ingrid B. Borecki, and et al
Genome sequence of enterovirus D68 from St. Louis, Missouri, USA, Kristine M. Wylie, Todd N. Wylie, Anthony Orvedahl, Richard S. Buller, Brandi N. Herter, Vincent Magrini, Richard K. Wilson, and Gregory A. Storch
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED., Tarik Hadzic, Dongkook Park, Katharine C. Abruzzi, Lin Yang, Jennifer S. Trigg, Remo Rohs, Michael Rosbash, and Paul H. Taghert
Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence, P Madden, N L. Saccone, and et al
Genome-wide profiling of PARP1 reveals an interplay with gene regulatory regions and DNA methylation, Narasimharao Nalabouthula, Taha Al-jumaily, Abdallah M. Eteleeb, Robert M. Flight, Shao Xiaorong, Hunter Moseley, Eric C. Rouchka, and Yvonne N. Fondufe-Mittendorf
Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer, Varun Chalivendra, Krishna Latha Kanchi, Michael D. Onken, Ashley E. Winkler, Elaine Mardis, and Ravindra Uppaluri
Genomic landscape of paediatric adrenocortical tumours, Richard K. Wilson, Elaine R. Mardis, and et al
Germline mutations in predisposition genes in pediatric cancer, Li Ding, Elaine R. Mardis, Richard K. Wilson, and et al
Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors, Talibah U. Metcalf, Rafael A. Cubas, Khader Ghneim, Michael J. Cartwright, Julien Van Grevenynghe, Justin M. Richner, David P. Olagnier, Peter A. Wilkinson, Mark J. Cameron, Byung S. Park, John B. Hiscott, Michael S. Diamond, Anne M. Wertheimer, Janko Nikolich-Zugich, and Elias K. Haddad
GPR18 controls reconstitution of mouse small intestine intraepithelial lymphocytes following bone marrow transplantation, Amy M. Becker, Derrick J. Callahan, Justin M. Richner, Jaebok Choi, John F. DiPersio, Michael S. Diamond, and Deepta Bhattacharya
Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies, Philip A. Ruzycki, Nicholas M. Tran, Vladimir J. Kefalov, Alexander V. Kolesnikov, and Shiming Chen
Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research, Pankaj Oberoi and et al
Gut resistome development in healthy twin pairs in the first year of life, Aimee M. Moore, Sara Ahmadi, Sanket Patel, Molly K. Gibson, Bin Wang, Malick I. Ndao, Elena Deych, William Shannon, Phillip I. Tarr, Barbara B. Warner, and Gautam Dantas
Head position change is not associated with acute changes in bilateral cerebral oxygenation in stable preterm infants during the first 3 days of life, Steve Ming-Che Liao, Rakesh Rao, and Amit M. Mathur
Hemorrhagic cystitis requiring bladder irrigation is associated with poor mortality in hospitalized stem cell transplant patients, Valary T. Raup, Aaron M. Potretzke, Brandon J. Manley, John A. Brockman, and Sam B. Bhayani
Hepatic steatosis as a marker of metabolic dysfunction, Elisa Fabbrini and Faidon Magkos
Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins, Teymur Kazakov, Feng Yang, Harish N. Ramanathan, Andrew Kohlway, Michael S. Diamond, and Brett D. Lindenbach
HIF-1α mediates isoflurane-induced vascular protection in subarachnoid hemorrhage, Eric Milner, Andrew W. Johnson, James W. Nelson, Michael D. Harries, Jeffrey M. Gidday, Byung Hee Han, and Gregory J. Zipfel
Higher throughput quantification of neutralizing antibody to herpes simplex viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, and Robert B. Belshe
High-intensity, unilateral resistance training of a non-paretic muscle group increases active range of motion in a severely paretic upper extremity muscle group after stroke, M. A. Urbin, Michelle L. Harris-Love, Alex R. Carter, and Catherine E. Lang
Highly sensitive image-derived indices of water-stressed plants using hyperspectral imaging in SWIR and histogram analysis, David M. Kim, Hairong Zhang, Haiying Zhou, Tommy Du, Qian Wu, Todd C. Mockler, and Mikhail Y. Berezin
High-specificity targeted functional profiling in microbial communities with ShortBRED, James Kaminski, Molly K. Gibson, Eric A. Franzosa, Nicola Segata, Gautam Dantas, and Curtis Huttenhower
Hookah-related Twitter chatter: A content analysis, Melissa J. Krauss, Shaina J. Sowles, Megan Moreno, Kidist Zewdie, Richard A. Grucza, Laura J. Beirut, and Patricia A. Cavazos-Rehg
Hormone replacement therapy, likely neither angel nor demon, Mitchell S. Wachtel, Shengping Yang, Sharmila Dissanaike, and Julie A. Margenthaler
Host-like carbohydrates promote bloodstream survival of Vibrio vulnificus in vivo, Jean-Bernard Lubin, Warren G. Lewis, Nicole M. Gilbert, Cory M. Weimer, Salvador Almagro-Moreno, E. F. Boyd, and Amanda L. Lewis
How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila, R. Faville, B. Kottler, G. J. Goodhill, P. J. Shaw, and B. van Swinderen
How do you know it is true? integrity in research and publications: AOA critical issue, Joseph A. Buckwalter, Vernon T. Tolo, and Regis J. O'Keefe
How genetic and other biological factors interact with smoking decisions, Laura Bierut and David Cesarini
Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment, Maorong Xie, Baoqin Xuan, Jiaoyu Shan, Deng Pan, Yamei Sun, Zhao Shan, Jinping Zhang, Dong Yu, Bin Li, and Zhlkang Qian
Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining, Vandna Kukshal, In-Kwon Kim, Gregory L. Hura, Alan E. Tomkinson, John A. Tainer, and Tom Ellenberger
Human gephyrin is encompassed within giant functional noncoding yin–yang sequences, Sharlee Climer, Alan R. Templeton, and Weixiong Zhang
Human T-Cell leukemia virus type 1 (HTLV- 1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling, Rajeshree Pujari, Richard Hunte, Remy Thomas, Louise van der Weyden, Dan Rauch, Lee Ratner, Jennifer K. Nyborg, Juan Carlos Ramos, Yoshimi Takai, and Noula Shembade
Human urine decreases function and expression of type 1 pili in uropathogenic Escherichia coli, Sarah E. Greene, MIchael E. Hibbing, James Janetka, Swaine L. Chen, and Scott J. Hultgren
Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo, Shannon L. Macauley, Molly Stanley, Emiley E. Caesar, Steven A. Yamada, Marcus E. Raichle, Ronaldo Perez, Thomas E. Mahan, Courtney L. Stuphen, and David M. Holtzman
Hypomagnesemia in critically ill sepsis patients, Dimitrios Velissaris, Vassilios Karamouzos, Charalampos Pierrakos, Diamanto Aretha, and Menelaos Karanikolas
IARC monographs: 40 years of evaluating carcinogenic hazards to humans, Ross C. Brownson and et al.
Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia, N. L. Bartlett and et al
Identification and analysis of divergent immune gene families within the Tasmanian devil genome, Katrina M. Morris, Yuanyuan Cheng, Wesley Warren, Anthony T. Papenfuss, and Katherine Belov
Identification of candidate adherent-invasive E. coli signature transcripts by genomic/transcriptomic analysis, Yuanhao Zhang, Leahana Rowehl, Julia M. Krumsiek, Erika P. Omer, Nurmohammad Shaikh, Phillip I. Tarr, Erica Sodergren, George M. Weinstock, Edgar C. Boedeker, Xuejian Xiong, John Parkinson, Daniel N. Frank, Ellen Li, and Grace Gathungu
Identification of hematomas in mild traumatic brain injury using an index of quantitative brain electrical activity, Leslie S. Prichep, Rosanne Naunheim, Jeffrey Bazarian, W. Andrew Mould, and Daniel Hanley
Identification of high-efficiency 3′GG gRNA motifs in indexed FASTA files with ngg2, Elisha D. Roberson
Identification of medically actionable secondary findings in the 1000 genomes, Emily Olfson, Catherine E. Cottrell, Nicholas O. Davidson, Christina A. Gurnett, Jonathan W. Heusel, Nathan O. Stitziel, Li-Shiun Chen, Sarah Hartz, Rakesh Nagarajan, Nancy L. Saccone, and Laura J. Bierut
Identification of multiple metabolic enzymes from mice cochleae tissue using a novel functional proteomics technology, David L. Wang, Hui Li, Ruqiang Liang, and Jianxin Bao
Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100, Shiyu Wang, Shuin Park, Vamsi K. Kodali, Jaeseok Han, Theresa Yip, Zhouji Chen, Nicholas O. Davidson, and Randal J. Kaufman
IFIT1 differentially interferes with translation and replication of alphavirus genomes and promotes induction of type I interferon, Josephine M. Reynaud, Dal Young Kim, Svetlana Atasheva, Aliaksandra Rasalouskaya, James P. White, Michael S. Diamond, Scott C. Weaver, Elena I. Frolova, and Ilya Frolov
IgG4-associated orbital and ocular inflammation, Cecilia S. Lee, George J. Harocopos, Courtney L. Kraus, Aaron Y. Lee, Gregory P. Van Stavern, Steven M. Couch, and P. Kumar Rao
IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis, Rei Nakamura, Abdoulaye Sene, Andrea Santeford, Abdelaziz Gdoura, Shunsuke Kubota, Nicole Zapata, and Rajendra S. Apte
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease, Jea-Hyun Baek, Rui Zeng, Julia Weinmann-Menke, M.Todd Valerius, Yukihiro Wada, Amrenda K. Ajay, Marco Colonna, and Vicki R. Kelley
IMAGES IN CLINICAL MEDICINE. Gastric pneumatosis, Ann-Christina Brady and Patrick A. Dillon
Imidazolium salts as small-molecule urinary bladder exfoliants in a murine model, Patrick O. Wagers, Kristin M. Tiemann, Kerri L. Shelton, William G. Kofron, Matthew J. Panzner, Karen L. Wooley, Wiley J. Youngs, and David A. Hunstad
Immediate postoperative pain: An atypical presentation of dropped gallstones after laparoscopic cholecystectomy, Samba Binagi, Jason Keune, and Michael Awad
Immune checkpoints and immunotherapy for colorectal cancer, Preet Paul Singh, Piyush K. Sharma, Gayathri Krishnan, and A. Craig Lockhart
Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: An opportunity for stewardship, Matthew P. Crotty, Shelby Meyers, Nicholas Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Marin H. Kollef, and Scott T. Micek
Impact of a structured review session on medical student psychiatry subject examination performance, Shan H. Siddiqi, Kevin J. Black, and Fay Y. Womer
Impact of neonatal intensive care bed configuration on rates of late-onset bacterial sepsis and methicillin-resistant Staphylococcus aureus colonization, Samuel Julian, Carey-Ann D. Burnham, Patricia Sellenriek, William D. Shannon, Aaron Hamvas, Phillip I. Tarr, and Barbara B. Warner
Impact of vitamin D supplementation on adiposity in African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, and G G. Bennett
Impaired fas-fas ligand interactions result in greater recurrent herpetic stromal keratitis in mice, Xiao-Tang Yin, Tammie L. Keadle, Jessicah Hard, John Herndon, Chelsea R. Del Rosso, Thomas A. Ferguson, and Patrick M. Stuart
Implementing administrative evidence based practices: Lessons from the field in six local health departments across the United States, Kathleen Duggan, Kristelle Aisaka, Rachel G. Tabak, Carson Smith, Paul Erwin, and Ross C. Brownson
Importance of decision support implementation in emergency department vancomycin dosing, Brett Faine, Nicholas Mohr, Kari K. Harland, Kathryn Rolfes, Blake Porter, and Brian M. Fuller
Inadequate source control and inappropriate antibiotics are key determinants of mortality in patients with intra-abdominal sepsis and associated bacteremia, Bethany Tellor, Lee P. Skrupky, William Symons, Eric High, Scott T. Micek, and John E. Mazuski
Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru, Andrew Wu, Philip J. Budge, John Williams, Marie R. Griffin, Kathryn M. Edwards, Monika Johnson, Yuwei Zhu, Stella Hartinger, Hector Verastegui, Ana I. Gil, Claudio F. Lanata, and Carlos G. Grijalva
Incidence of surgical site infection following mastectomy with and without immediate reconstruction using private insurer claims data, Margaret A. Olsen, Katelin B. Nickel, Ida K. Fox, Julie A. Margenthaler, Kelly E. Ball, Daniel Mines, Anna E. Wallace, and Victoria J. Fraser
Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: Implications for immune-mediated cancer therapy, Ivy Wilkinson-Ryan, Julius Kim, Sojung Kim, Ferhat Ak, Lindzy Dodson, Marco Colonna, Matthew Powell, David Mutch, Dirk Spitzer, Ted Hansen, Simon P. Goedegebuure, David Curiel, and William Hawkins
Increased exclusivity of breastfeeding associated with reduced gut inflammation in infants, Eshia Moodley-Govender, Helen Mulol, Jennifer Stauber, Mark Manary, and Anna Coutsoudis
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling, Courtney M. Karner, Emel Esen, Adewole L. Okunade, Bruce W. Patterson, and Fanxin Long
Increased reward-related behaviors during sleep and wakefulness in sleepwalking and idiopathic nightmares, Lampros Perogamvros, Kristoffer Aberg, Marianne Gex-Fabry, Stephen Perrig, C. Robert Cloninger, and Sophie Schwartz
Increasing the reliability of fully automated surveillance for central line–associated bloodstream infections, Rachael E. Snyders, Ashleigh J. Goris, Kathleen A. Gase, Carole L. Leone, Joshua A. Doherty, and Keith F. Woeltje