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Submissions from 2015

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Relationship between abuse and neglect in childhood and diabetes in adulthood: Differential effects by sex, national longitudinal study of adolescent health, Alexis E. Duncan, Wendy F. Auslander, Kathleen K. Bucholz, Darrell L. Hudson, Richard I. Stein, and Neil H. White

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Renal DCE-MRI model selection using Bayesian probability theory, Scott C. Beeman, Patrick Osei-Owusu, Duan Chong, John Engelbah, Larry G. Bretthorst, Joseph J. H Ackerman, Kendall J. Blumer, and Joel R. Garbow

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Reproductive and hormonal factors and mortality among women with colorectal cancer in the NIH-AARP Diet and Health Study, H. Arem, Y. Park, A. S. Felix, A. Zervoudakis, L. A. Brinton, C. E. Matthews, and M. J. Gunter

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Research priorities to improve the management of acute malnutrition in infants aged less than six months (MAMI), Sagar Mehta and et al

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Resistance to the antimicrobial agent fosmidomycin and an FR900098 prodrug through mutations in the deoxyxylulose phosphate reductoisomerase gene (dxr), Christopher M. Armstrong, David J. Meyers, Leah S. Imlay, Caren Freel Meyers, and Audrey R. Odom

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Response to nodal morphogen gradient is determined by the kinetics of target gene induction, Julien Dubrulle, Benjamin M. Jordan, Laila Akhmetova, Jeffrey A. Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, and Alexander F. Schier

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Resting-state temporal synchronization networks emerge from connectivity topology and heterogeneity, Adrian Ponce-Alvarez, Gustavo Deco, Patric Hagmann, Gian Luca Romani, Dante Mantini, and Maurizio Corbetta

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Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model, Dudley W. Lamming, Nicole E. Cummings, Antonella L. Rastelli, Feng Gao, Edda Cava, Beatrice Bertozzi, Francesco Spelta, Roberto Pili, and Luigi Fontana

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Retroperitoneal robot-assisted partial nephrectomy for posterior renal masses is associated with earlier hospital discharge: A single-institution retrospective comparison, Eric H. Kim, Jeffery A. Larson, Aaron M. Potretzke, Nicholas K. Hulsey, Sam B. Bhayani, and R. Sherburne Figenshau

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Review of measures of worksite environmental and policy supports for physical activity and healthy eating, J. Aaron Hipp, Dominic N. Reeds, Margaret A. van Bakergem, Christine M. Marx, Ross C. Brownson, Surya C. Pamulapati, and Christine M. Hoehner

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Review of robot-assisted partial nephrectomy in modern practice, Aaron M. Potretzke, John Weaver, and Brian M. Benway

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Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma, Jeffrey F. Moley and et al

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Revolutionizing Alzheimer's disease and clinical trials through biomarkers, Niklas Mattsson, Maria C. Carrillo, Robert A. Dean, Michael D. Devous Sr., Tania Nikolcheva, Pedro Pesini, Hugh Salter, William Z. Potter, Reisa S. Sperling, Randall J. Bateman, Lisa J. Bain, and Enchi Liu

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Reward-based decision signals in parietal cortex are partially embodied, Jan Kubanek and Lawrence H. Snyder

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Reward enhances tic suppression in children within months of tic disorder onset, Deanna J. Greene, Jonathan M. Koller, Amy Robichaux-Viehoever, Emily C. Bihun, Bradley L. Schlaggar, and Kevin J. Black

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Rhoptry proteins ROP5 and ROP18 are major murine virulence factors in genetically divergent South American strains of Toxoplasma gondii, Michael S. Behnke, Asis Khan, Elvin J. Lauron, John R. Jimah, Qiuling Wang, Niraj H. Tolia, and L. David Sibley

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Ribosomes slide on lysine-encoding homopolymeric A stretches., Kristin S. Koutmou, Anthony P. Schuller, Julie L. Brunelle, Aditya Radhakrishnan, Sergej Djuranovic, and Rachel Green

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Rice Xa21 primed genes and pathways that are critical for combating bacterial blight infection, Hai Peng, Zheng Chen, Zhiwei Fang, Junfei Zhou, Zhihui Xia, Lifen Gao, Lihong Chen, Lili Li, Tiantian Li, Wenxue Zhai, and Weixiong Zhang

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RIG-I signaling Is essential for influenza B virus-induced rapid interferon gene expression, Sanna M. Makela, Pamela Osterlund, Veera Westenius, Sinikka Latvala, Michael S. Diamond, Michael Gale Jr., and Ilkka Julkunen

Risk factors for acquisition and loss of Clostridium difficile colonization in hospitalized patients, Erik R. Dubberke, Kimberly A. Reske, Sondra Seiler, Tiffany Hink, Jennie H. Kwon, and Carey-Ann D. Burnham

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RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth, Anna C. Solga, Winnie W. Pong, Keun-Young Kim, Patrick J. Cimino, Joseph A. Toonen, Jason Walker, Todd Wylie, Vincent Magrini, Malachi Griffith, Obi L. Griffith, Amy Ly, Mark H. Ellisman, Elaine R. Mardis, and David H. Gutmann

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Role of ABCA7 loss-of-function variant in Alzheimer's disease: A replication study in European–Americans, Jorge L. Del-Aguila, Maria Victoria Fernandez, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, and Carlos Cruchaga

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Role of copper efflux in pneumococcal pathogenesis and resistance to macrophage-mediated immune clearance, Michael D L Johnson, Thomas E. Kehl-Fie, Roger Klein, Jacqueline Kelly, Corinna Burnham, Beth Mann, and Jason W. Rosch

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Role of cortactin homolog HS1 in transendothelial migration of Natural Killer cells, Suranjana Mukherjee, Joanna Kim, Olivia L. Mooren, Stefanie T. Shahan, Megan Cohan, and John A. Cooper

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Role of hypoxia inducible factor-1α (HIF-1α) in innate defense against uropathogenic Escherichia coli infection, Ann E. Lin, Federico C. Beasley, Joshua Olson, Nadia Keller, Robert A. Shalwitz, Thomas J. Hannan, Scott J. Hultgren, and Victor Nizet

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Role of membrane biophysics in Alzheimer's–related cell pathways, Donghui Zhu, Brittani L. Bungart, Xiaoguang Yang, Zhaxybay Zhumadilov, and James C-M. Lee

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Role of RNase H1 in DNA repair: Removal of single ribonucleotide misincorporated into DNA in collaboration with RNase H2, Elias Tannous, Eiko Kanaya, and Shigenori Kanaya

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Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology, Yuichi Ishikawa, Manami Maeda, Mithun Pasham, Francois Aguet, Silvia K. Tacheva-Grigorova, Takeshi Masuda, Hai Yi, Sung-Uk Lee, Jian Xu, Julie Teruya-Feldstein, Maria Ericsson, Ann Mullally, John Heuser, Tom Kirchhausen, and Takahiro Maeda

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Role of visual and non-visual cues in constructing a rotation-invariant representation of heading in parietal cortex, Adhira Sunkara, Gregory C. DeAngelis, and Dora E. Angelaki

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SATB2 is a sensitive marker for lower gastrointestinal well-differentiated neuroendocrine tumors, Zhongwu Li, Jing Yuan, Lixin Wei, Kaiyong Mei, Junqiu Yue, Hongwen Gao, Miao Zhang, Ling Jia, Qiang Kang, Xiaozheng Huang, and Dengfeng Cao

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Scimitar syndrome: Multimodal imaging before and after repair, Sara C. Martinez, Pirooz Eghtesady, Sanjeev Bhalla, and Philip A. Ludbrook

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Scratching the surface – tobacco-induced bacterial biofilms, Justin A. Hutcherson, David A. Scott, and Juhi Bagaitkar

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Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells, Monica Sala-Rabanal, Zeynep Yurtsever, Colin G. Nichols, and Tom J. Brett

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Securely measuring the overlap between private datasets with cryptosets, S. Joshua Swamidass, Matthew Matlock, and Leon Rozenblit

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Selective blockade of interferon-α and -β reveals their non-redundant functions in a mouse model of West Nile virus infection, Kathleen C. F. Sheehan, Helen M. Lazear, Michael S. Diamond, and Robert D. Schreiber

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Selective cognitive and psychiatric manifestations in Wolfram Syndrome, Allison N. Bischoff, Angela M. Reiersen, Anna Buttlaire, Amal Al-lozi, Tasha Doty, Bess A. Marshall, Tamara Hershey, and Washington University Wolfram Syndrome Research Group

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Seminoma presenting as renal mass, inferior vena caval thrombus, and regressed testicular mass, Valary T. Raup, Michael H. Johnson, Jonathan R. Weese, Ian S. Hagemann, Stephen D. Marshall, and Steven B. Brandes

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Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior, Ignacio Sarria, Johan Pahlberg, Yan Cao, Alexander V. Kolesnikov, Vladimir J. Kefalov, Alapakkam P. Sampath, and Kirill A. Martemyanov

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Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits, Richard K. Wilson, Wesley Warren, and et al

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Sexual selection and cancer biology, Joshua B. Rubin

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Sickle cell disease: Wheeze or asthma?, Robyn T. Cohen, Elizabeth S. Klings, and Robert C. Strunk

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Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte, Longsen Han, Juan Ge, Liang Zhang, Rujun Ma, Xiaojing Hou, Bin Li, Kelle Moley, and Qiang Wang

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slan/M-DC8+ cells constitute a distinct subset of dendritic cells in human tonsils, Alessandra Micheletti, Giulia Finotti, Federica Calzetti, Silvia Lonardi, Elisa Zoratti, Mattia Bugatti, Stefania Stefini, William Vermi, and Marco A. Cassatella

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Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease, Erik S. Musiek, David D. Xiong, and David M. Holtzman

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Small sized EGFR1 and HER2 specific bifunctional antibody for targeted cancer therapy, Li Ding, Caiping Tian, Song Feng, Guissi Fida, Congying Zhang, Yuxiang Ma, Guanhua Ai, Samuel Achilefu, and Yueqing Gu

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Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model, Miwa Tanaka, Shuichi Yamaguchi, Yukari Yamazaki, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Patrick Y. Jay, Tetsuo Noda, and Takuro Nakamura

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Spatial and temporal characteristics of error-related activity in the human brain, Maital Neta, Francis M. Miezin, Steven M. Nelson, Joseph W. Dubis, Nico U. F. Dosenbach, Bradley L. Schlaggar, and Steven E. Petersen

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Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production, Yong Zhang, Michael Holtzman, and et al

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Spatiotemporal regulation of a Legionella pneumophila T4SS substrate by the metaeffector SidJ, Kwang Cheol Jeong, Jessica A. Sexton, and Joseph P. Vogel

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SPEAR Trial: Smartphone Pediatric ElectrocARdiogram Trial, Hoang H. Nguyen, George F. Van Hare, Michael Rudokas, Tammy Bowman, and Jennifer N. A. Silva

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Species-specific transmission of novel picornaviruses in lemurs, Efrem S. Lim, Sharon L. Deem, Ingrid J. Porton, Song Cao, and David Wang

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Spontaneous rupture of an aortocoronary saphenous vein graft aneurysm, Matthew C. Henn and Lucas W. Henn

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Standardization and normative data of the Greek version of the temperament and character inventory (TCI), Konstantinos N. Fountoulakis, Sandor Rozsa, Melina Siamouli, Katerina Moutou, Eleonora Pantoula, and Claude Robert Cloninger

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STAT1 modification improves therapeutic effects of interferons on lung cancer cells, Junjie Chen, Jialu Zhao, Lefu Chen, Nian Dong, Zhaojian Ying, Zhenzhen Cai, Dongxiang Ji, Yong Zhang, Li Dong, Yuping Li, Lei Jiang, Michael J. Holtzman, and Chengshui Chen

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Stratification of surgical site infection by operative factors and comparison of infection rates after hernia repair, Margaret A. Olsen, Katelin B. Nickel, Anna E. Wallace, Daniel Mines, Victoria J. Fraser, and David K. Warren

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Strengths and weaknesses of a planar whole-body method of 153Sm dosimetry for patients with metastatic osteosarcoma and comparison with three-dimensional dosimetry, Donika Plyku, David M. Loeb, Andrew Prideaux, Sébastien Baechler, Richard L. Wahl, George Sgouros, and Robert F. Hobbs

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Streptococcus pyogenes malate degradation pathway links pH regulation and virulence, Elyse Paluscio and Michael G. Caparon

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Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology, N. S. Corral-Frías, Y. S. Nikolova, L. J. Michalski, D. A. A. Baranger, A. R. Hariri, and R. Bogdan

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Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design, Edwin Chen, Nichole D. Salinas, Francis B. Ntumngia, John H. Adams, and Niraj H. Tolia

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Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily, Christopher A. Nelson, Megan L. Epperson, Sukrit Singh, Jabari I. Elliott, and Daved H. Freemont

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Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways, Sukrit Suksombat, Rustem Khafizov, Alexander G. Kozlov, Timothy M. Lohman, and Yann R. Chemla

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Structure of acidic pH dengue virus showing the fusogenic glycoprotein trimers, Xinzheng Zhang, Ju Sheng, S. Kyle Austin, Tabitha E. Hoornweg, Jolanda M. Smit, Richard J. Kuhn, Michael S. Diamond, and Michael G. Rossmann

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Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity, Lee W. Goneau, Thomas J. Hannan, Roderick A. MacPhee, Drew J. Schwartz, Jean M. Macklaim, Gregory B. Gloor, Hassan Razvi, Gregor Reid, Scott J. Hultgren, and Jeremy P. Burton

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Sugarcoated isolation: Evidence that social avoidance is linked to higher basal glucose levels and higher consumption of glucose, Tsachi Ein-Dor, James A. Coan, Abira Reizer, Elizabeth B. Gross, Dana Dahan, Meredyth A. Wegener, Rafael Carel, Claude R. Cloninger, and Ada H. Zohar

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Sumoylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila, Amjad M. Nasir, Qianyi Yang, Douglas L. Chalker, and James D. Forney

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Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation, Huimin Yan, Hui-fang Zhou, Ying Hu, and Christine T.N. Pham

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Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis, Tim S. Ellison, Samuel J. Atkinson, Veronica Steri, Benjamin M. Kirkup, Michael E J Preedy, Robert T. Johnson, Christina Ruhrberg, Dylan R. Edwards, Jochen G. Schneider, Katherine Weilbaecher, and Stephen D. Robinson

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Surgery for lymph node metastases of medullary thyroid carcinoma, Linda X. Jin and Jeffrey F. Moley

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Surgical anatomy of the uncinate process and transverse foramen determined by computer tomography, Moon S. Park, Seong-Hwan Moon, Tae-Hwan Kim, Jae K. Oh, Jae K. Jung, Hyung J. Kim, and K. Daniel Riew

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Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy, Anna K. Brady, Jonathan D. McNeill, Brendan Judy, Joshua Bauml, Tracey L. Evans, Roger B. Cohen, Corey Langer, Anil Vachani, and Charu Aggarwal

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Sustainability of evidence-based healthcare: Research agenda, methodological advances, and infrastructure support, Enola Proctor, Douglas Luke, Annaliese Calhoun, Curtis McMillen, Ross Brownson, Stacey McCrary, and Margaret Padek

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Synaptic remodeling of neuronal circuits in early retinal degeneration, Florentina Soto and Daniel Kerschensteiner

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Synechococcus elongatus UTEX 2973, a fast growing cyanobacterial chassis for biosynthesis using light and CO2, Jingjie Yu, Michelle Liberton, Paul F. Cliften, Richard D. Head, Jon M. Jacobs, Richard D. Smith, David W. Koppenaal, Jerry J. Brand, and Himadri B. Pakrasi

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Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease, Guruswami S.M. Sundaram, Dhruva Dhavale, Julie L. Prior, Jothilingam Sivapackiam, Richard Laforest, Paul Kotzbauer, and Vijay Sharma

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Systemic EP4 inhibition increases adhesion formation in a murine model of flexor tendon repair, Michael B. Geary, Caitlin A. Orner, Fatima Bawany, Hani A. Awad, Warren C. Hammert, Regis J. O'Keefe, and Alayna E. Loiselle

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Targeted treatments for multiple myeloma: Specific role of carfilzomib, Dhivya Sugumar, Jesse Keller, and Ravi Vij

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Targeting brain tumor cAMP: The case for sex-specific therapeutics, Nicole M. Warrington, Tao Sun, and Joshua B. Rubin

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Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models, Muriel Elhai, Gilles Chiocchia, Carmen Marchiol, Franck Lager, Gilles Renault, Marco Colonna, Guenter Bernhardt, Yannick Allanore, and Jerome Avouac

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Targeting lysine deacetylases (KDACs) in parasites, Qi Wang, Bruce A. Rosa, Bakela Nare, Kerrie Powell, Sergio Valente, Dante Rotili, Antonello Mai, Garland R. Marshall, and Makedonka Mitreva

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Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription, Shugaku Takeda, Satoru Sasagawa, Toshinao Oyama, Adam C. Searleman, Todd D. Westergard, Emily H. Cheng, and James J. Hsieh

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TBX6 null variants and a common hypomorphic allele in congenital scoliosis, H. Al-Kateb, S. Kulkarni, and et al

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T cell metabolism drives immunity, Michael D. Buck, David O'Sullivan, and Erika L. Pearce

Temporal trends in the systemic inflammatory response syndrome, sepsis, and medical coding of sepsis, Benjamin S. Thomas, S. Reza Jafarzadeh, David K. Warren, Sandra McCormick, Victoria J. Fraser, and Jonas Marschall

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Testicular interposition flap for repair of perineal urinary fistulae: A novel surgical technique, Valary T. Raup, Jairam R. Eswara, Stephen D. Marshall, and Steven B. Brandes

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Testicular leydig cell tumor with metachronous lesions: Outcomes after metastasis resection and cryoablation, Julio J. Geminiani, Stephen D. Marshall, Tammy S. Ho, and Steven B. Brandes

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The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with G alpha(12/13) and RhoA, Sarah D. Ackerman, Cynthia Garcia, Xianhua Piao, David H. Gutmann, and Kelly R. Monk

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The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development, Stefanie Giera, Yiyu Deng, Rong Luo, Sarah D. Ackerman, Amit Mogha, Kelly R. Monk, Yanqin Ying, Sung-Jin Jeong, Manabu Makinodan, Allison R. Bialas, Bernard S. Chang, Beth Stevens, Gabriel Corfas, and Xianhua Piao

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The Affordable Care Act and implications for health care services for American Indian and Alaska Native individuals, Raven E. Ross, Lauren D. Garfield, Derek S. Brown, and Ramesh Raghavan

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The Alternaria genomes database: A comprehensive resource for a fungal genus comprised of saprophytes, plant pathogens, and allergenic species, Ha X. Dang, Barry Pryor, Tobin Peever, and Christopher B. Lawrence

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The amazing brain, Krikor Dikranian

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The anatomical distribution of genetic associations, Alan Wells, Nathan Kopp, Xiaoxiao Xu, David R. O'Brien, Wei Yang, Arye Nehorai, Tracy L. Adair-Kirk, Raphael Kopan, and J D. Dougherty

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The association of parental temperament and character on their children’s behavior problems, Soo Jin Lee, C. Robert Cloninger, Soo Hyun Park, and Han Chae

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The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma, David Y A Dadey, Vaishali Kapoor, Arpine Khudanyan, Fumihiko Urano, Albert H. Kim, Dinesh Thotala, and Dennis E. Hallahan

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The DEK oncoprotein is a critical component of the EKLF/KLF1 enhancer in erythroid cells, Felix Lohmann, Mohan Dangeti, Shefali Soni, Xiaoyong Chen, Antanas Planutis, Margaret H. Baron, Kyunghee Choi, and James J. Bieker

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The DHX33 RNA helicase promotes mRNA translation initiation, Yandong Zhang, Jin You, Xingshun Wang, and Jason Weber

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The diagnosis and treatment of vesicoureteral reflux: An update, Adam Rensing and Paul Austin

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The distribution and mutagenesis of short coding INDELs from 1,128 whole exomes, Danny Challis, Lilian Antunes, Erik Garrison, Eric Banks, Uday S. Evani, Donna Muzny, Ryan Poplin, Richard A. Gibbs, Gabor Marth, and Fuli Yu

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The Drosophila prosecretory transcription factor dimmed is dynamically regulated in adult enteroendocrine cells and protects against Gram-negative infection, Katherine Beebe, Dongkook Park, Paul H. Taghert, and Craig A. Micchelli

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The dynamic genome and transcriptome of the human fungal pathogen Blastomyces and close relative Emmonsia, Vincent Magrini, Makedonka Mitreva, Elaine R. Mardis, and et al.

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The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children, M. Isabel Ordiz, Thaddaeus D. May, Kathie Mihindukulasuriya, John Martin, Jan Crowley, Phillip I. Tarr, Kelsey Ryan, Elissa Mortimer, Geetha Gopalsamy, Ken Maleta, Makedonka Mitreva, Graeme Young, and Mark J. Manary