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Submissions from 2014

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HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors, Magda Zammataro, Maria Angela Sortino, Carmela Parenti, Robert W. Gereau IV, and Santina Chiechio

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Health care system collaboration to address chronic diseases: A nationwide snapshot from state public health practitioners, Lindsay Elliott, Timothy D. McBride, Peg Allen, Rebekah R. Jacob, Ellen Jones, Jon Kerner, and Ross C. Brownson

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Healthy weight regulation and eating disorder prevention in high school students: A universal and targeted web-based intervention, Megan Jones, Katherine T. Lynch, Andrea E. Kass, Amanda Burrows, Joanne W. Williams, Denise E. Wilfley, and Craig B. Taylor

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Helminth.net: expansions to Nematode.net and an introduction to Trematode.net., John Martin, Bruce A. Rosa, Philip Ozersky, Kymberlie Hallsworth-Pepin, Xu Zhang, Veena Bhonagiri-Palsikar, Rahul Tyagi, Qi Wang, Young-Jun Choi, Xin Gao, Samantha N. McNulty, Paul J. Brindley, and Makedonka Mitreva

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Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis, Nayan J. Sarma, Venkataswarup Tiriveedhi, Jeffrey S. Crippin, William C. Chapman, and Thalachallour Mohanakumar

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Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6, Martina Bielaszewska, Roswitha Schiller, Lydia Lammers, Andreas Bauwens, Angelika Fruth, Barbara Middendorf, M. Alexander Schmidt, Phillip I. Tarr, Ulrich Dobrindt, Helge Karch, and Alexander Mellmann

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High-coverage sequencing and annotated assemblies of the budgerigar genome, Ganeshkumar Ganapathy, Wesley C. Warren, and et al

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High level expression of a glutamate-gated chloride channel gene in reproductive tissues of Brugia malayi may explain the sterilizing effect of ivermectin on filarial worms, Ben Wen Li, Amy C. Rush, and Gary J. Weil

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High pressure freezing/freeze substitution fixation improves the ultrastructural assessment of Wolbachia endosymbiont – filarial nematode host interaction, Kerstin Fischer, Wandy L. Beatty, Gary J. Weil, and Peter U. Fischer

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High-resolution quantification of hepatitis C virus genome-wide mutation load and its correlation with the outcome of peginterferon-alpha2a and ribavirin combination therapy, Weihua Wang, Xiaoan Zhang, Yanjuan Xu, George M. Weinstock, Adrian M. Di Bisceglie, and Xiaofeng Fan

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High-throughput functional testing of ENCODE segmentation predictions, Jamie C. Kwasnieski, Christopher Fiore, Hemangi G. Chaudhari, and Barak A. Cohen

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Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference, George S. Portugal, Ream Al-Hasani, Amanda K. Fakira, Jose L. Gonzalez-Romero, Zare Melyan, Jordan G. McCall, Michael R. Bruchas, and Jose A. Moron

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How I do it: Minimally invasive Cox-Maze IV procedure, Lindsey L. Saint, Christopher P. Lawrance, Jeremy E. Leidenfrost, Jason O. Roberston, and Ralph J. Damiano Jr.

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How local excitation-inhibition ratio impacts the whole brain dynamics, Gustavo Deco, Adrian Ponce-Alvarez, Patric Hagmann, Gian Luca Romani, Dante Mantini, and Maurizio Corbetta

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How to avoid microaspiration? A key element for the prevention of ventilator-associated pneumonia in intubated ICU patients, Stijn I. Blot, Jan Poelaert, and Marin Kollef

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Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: An IVUS-based fluid-structure interaction multi-patient study, Rui Fan, Dalin Tang, Chun Yang, Jie Zheng, Richard Bach, Liang Wang, David Muccigrosso, Kristen Billiar, Jian Zhu, Genshan Ma, Akiko Maehara, and Gary S. Mintz

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Human cytomegalovirus pUL79 Is an elongation factor of RNA polymerase II for viral gene transcription, Yi-Chieh Perng, Jessica A. Campbell, Deborah J. Lenschow, and Dong Yu

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Human cytomegalovirus US28 facilitates cell-to-cell viral dissemination, Vanessa M. Noriega, Thomas J. Gardner, Veronika Redmann, Gerold Bongers, Sergio A. Lira, and Domenico Tortorella

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Hybrid mice reveal parent-of-origin and cis- and trans- regulatory effects in the retina, Susan Q. Shen, Ernest Turro, and Joseph C. Corbo

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Identification and characterization of alternative splicing in parasitic nematode transcriptomes, Sahar Abubucker, Samantha N. McNulty, Bruce A. Rosa, and Makedonka Mitreva

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Identification of Alternative Transcripts Encoding the Essential Murine Gammaherpesvirus Lytic Transactivator RTA, Brian S. Wakeman, L. Steven Johnson, Clinton R. Paden, Kathleen S. Gray, Herbert W. Virgin, and Samuel H. Speck

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Identification of pathologic features associated with “ulcerative colitis-like” Crohn’s disease, Samuel D. James, Paul E. Wise, Tania Zuluaga-Toro, David A. Schwartz, M. Kay Washington, and Chanjuan Shi

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Identification of rare variants in Alzheimer's disease, Jenny Lord, Alexander J. Lu, and Carlos Cruchaga

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Identifying cryptic population structure in multigenerational pedigrees in a Mexican American sample, Robert C. Culverhouse, Anthony L. Hinrichs, and Brian K. Suarez

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IL-15 deficient Tax mice reveal a role for IL-1α in tumor immunity, Daniel A. Rauch, John C. Harding, and Lee Ratner

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IL-6 stimulates intestinal epithelial proliferation and repair after injury, Kristine A. Kuhn, Nicholas A. Manieri, Ta-Chiang Liu, and Thaddeus S. Stappenbeck

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Illustrated techniques for performing the Cox-Maze IV procedure through a right mini-thoracotomy, Jason O. Robertson, Lindsey L. Saint, Jeremy E. Leidenfrost, and Ralph J. Damiano Jr.

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Immuno-PET of epithelial ovarian cancer: Harnessing the potential of CA125 for non-invasive imaging, Sai Kiran Sharma, Melinda Wuest, Monica Wang, Darryl Glubrecht, Bonnie Andrais, Suzanne E. Lapi, and Frank Wuest

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Impact of genetic background on neonatal lethality of Gga2 gene-trap mice, Balraj Doray, Jennifer Govero, and Stuart Kornfeld

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Impact of host age and parity on susceptibility to severe urinary tract infection in a murine model, Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, and Amanda L. Lewis

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Impact of radiation therapy on survival in patients with triple‑negative breast cancer, Lauren T. Steward, Feng Gao, Marie A. Taylor, and Julie A. Margenthaler

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Inactivation of SAM-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain, Yan Liu, Bin Wu, George Weinstock, David H. Walker, and Xue-jie Yu

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Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection, Marion C. Lanteri, Michael S. Diamond, Jacqueline P. Law, Glen M. Chew, Shiquan Wu, Heather C. Inglis, Derek Wong, Michael P. Busch, Philip J. Norris, and Lishomwa C. Ndhlovu

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Increased iron sequestration in alveolar macrophages in chronic obtructive pulmonary disease, Quentin Philippot, Gaetan Deslee, Tracy L. Adair-Kirk, Jason C. Woods, Derek Byers, Susan Conradi, Sandra Dury, Jeanne Marie Perotin, Francois Lebargy, Christelle Cassan, Richard Le Naour, Michael J. Holtzman, and Richard A. Pierce

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Information-seeking among chronic disease prevention staff in state health departments: Use of academic journals, Jenine K. Harris, Peg Allen, Rebekah R. Jacob, Lindsay Elliott, and Ross C. Brownson

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Inhibition of cyclooxygenase-2 prevents chronic and recurrent cystitis, Thomas J. Hannan, Terrence E. Riehl, Jana M. Binkley, Drew J. Schwartz, Hiroyuki Miyoshi, Thaddeus S. Stappenbeck, William F. Stenson, Marco Colonna, Scott J. Hultgren, and et al

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Inputs drive cell phenotype variability, James Park, Anthony Brureau, Kate Kernan, Alexandria Starks, Sonali Gulati, Babatunde Ogunnaike, James Schwaber, and Rajanikanth Vadigepalli

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Integrated analysis of germline and somatic variants in ovarian cancer, Krishna L. Kanchi, Kimberly J. Johnson, Charles Lu, Michael D. McLellan, Michael C. Wendl, Qunyuan Zhang, Daniel C. Koboldt, Mingchao Xie, Cyriac Kandoth, Joshua F. McMichael, Matthew A. Wyczalkowski, David E. Larson, Heather K. Schmidt, Christopher A. Miller, Robert S. Fulton, Elaine R. Mardis, Todd E. Druley, Timothy A. Graubert, Richard K. Wilson, Li Ding, and et al

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Integrated RNA and DNA sequencing improves mutation detection in low purity tumors, Matthew D. Wilkerson, Christopher R. Cabanski, Wei Sun, Katherine A. Hoadley, Vonn Walter, Lisle E. Mose, Melissa A. Troester, Peter S. Hammerman, Joel S. Parker, Charles M. Perou, and D. Neil Hayes

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Integrated school-based surveillance for soil-transmitted helminth infections and lymphatic filariasis in Gampaha District, Sri Lanka, Sharmini Guanwardena, Nipul K. Guanawardena, Ganga Kahathuduwa, Nadira D. Karunaweera, Nilanthi R. de Silva, Udaya B. Ranasinghe, Sandhya D. Samarasekara, Kumara C. Nagodavithana, Ramakrishna U. Rao, Maria P. Rebollo, and Gary J. Weil

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Integration of multiple determinants in the neuronal computation of economic values, Anantha P. Raghuraman and Camillo Padoa-Schioppa

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Integration of sequence data from a consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene, Robert S. Fulton and et al

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Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile Virus infection, Larissa B. Thackray, Bimmi Shrestha, Justin M. Richner, Jonathan J. Miner, Amelia K. Pinto, Helen M. Lazear, and Michael Gale Jr.

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International Radical Cystectomy Consortium: A way forward, Adam S. Kibel and et al.

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Intestine-specific deletion of microsomal triglyceride transfer protein increases mortality in aged mice, Zhe Liang, Yan Xie, Jessica A. Dominguez, Elise R. Breed, Benyam P. Yoseph, Eileen M. Burd, Alton B. Farris, Nicholas O. Davidson, and Craig M. Coopersmith

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Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus, Carolyn A. Purgert, Yukitoshi Izumi, Yuh-Jin I. Jong, Vikas Kumar, Charles F. Zorumski, and Karen L. O'Malley

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Intravenous immunoglobulin in BK virus nephropathy, Elizabeth I. Anyaegbu and Stanley P. Hmiel

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Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus, John R. Cirrito and et al

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Intrawound vancomycin powder eradicates surgical wound contamination: An in vivo rabbit study, Lukas P. Zebala, Tapanut Chuntarapas, Michael P. Kelly, Michael Talcott, Suellen Greco, and K. Daniel Riew

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Introduction to "A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates", Erik R. Dubberke, Deborah S. Yokoe, Deverick J. Anderson, Sean M. Berenholtz, David P. Calfee, Katherine Ellingson, Dale N. Gerding, Janet Haas, Keith S. Kaye, Michael Klompas, Evelyn Lo, Jonas Marschall, Leonard A. Mermel, Lindsau Nicolle, and et al

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Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, and Daniel E.L. Promislow

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Invasive salmonellosis by the very rare salmonella choleraesuis in a returning traveler on a tumor necrosis factor-α inhibitor, Uzoamaka A. Eke, Harry Conte, Paula Anderson, and Robert W. Lyons

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In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia, Xingmin Feng, Phillip Scheinberg, Angelique Biancotto, Olga Rios, Sarah Donaldson, Colin Wu, Haiyun Zheng, Kazuya Sato, Danielle M. Townsley, J. Philip McCoy, and Neal S. Young

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In vivo evaluation of a reverse thermosensitive polymer for ureteroscopy with laser lithotripsy: Porcine model, Jonathan M. Mobley, Goutham Vemana, Marshall Strother, Robert Sherburne Figenshau, Joel M. Vetter, Jeffrey Larson, and Brian M. Benway

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In vivo functional analysis of the human NF2 tumor suppressor gene in Drosophila, Heather S. Gavilan, Rima M. Kulikauskas, David H. Gutmann, and Richard G. Fehon

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In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin, Usha P. Andley, James P. Malone, and R. Reid Townsend

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Isoprenoid Biosynthesis in Plasmodium falciparum, Ann M. Guggisberg, Rachel E. Amthor, and Audrey R. Odom

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Is the relationship between binge eating episodes and personality attributable to genetic factors?, Rachel Koren, Melissa A. Munn-Chernoff, Alexis E. Duncan, Kathleen K. Bucholz, Pamela A.F. Madden, Andrew C. Heath, and Arpana Agrawal

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Joint testing of genotypic and gene-environment interaction identified novel association for BMP4 with non-syndromic CL/P in an Asian population using data from an International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, and Terri H. Beaty

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KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G1-phase lymphocytes, Anthony T. Tubbs, Yair Dorsett, Elizabeth Chan, Beth Helmink, Baeck-Seung Lee, Putzer Hung, Rosmy George, Andrea L. Bredemeyer, Anuradha Mittal, Rohit V. Pappu, Dipanjan Chowdhury, Nima Mosammaparast, Michael S. Krangel, and Barry P. Sleckman

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Keep on laying eggs mama, RNAi my reproductive aging blues away, Sandeep Kumar, Zuzana Kocsisova, and Kerry Kornfeld

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Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia, David G. Cotter, Baris Ercal, Xiaojing Huang, Jamison M. Leid, Andre d'Avignon, Mark J. Graham, Dennis J. Dietzen, Elizabeth M. Brunt, Gary J. Patti, and Peter A. Crawford

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Key issues and opportunities in the evolving health-care marketplace: AOA critical issues, Kristin Olds Glavin, Daniel B. Murrey, Joel C. Porter, Donald Brunn, and Rick W. Wright

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Kidney transplantation in children, Vikas R. Dharnidharka, Paolo Fiorina, and William E. Harmon

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Kids, candy, brain and behavior: Age differences in responses to candy gains and losses, Katherine R. Luking, Joan L. Luby, and Deanna M. Barch

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Kinases and pseudokinases: Lessons from RAF, Andrey S. Shaw, Alexandr P. Kornev, Jiancheng Hu, Lalima G. Ahuja, and Susan S. Taylor

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Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E, Benjamin Vitre, Nikita Gudimchuk, Ranier Borda, Yumi Kim, John E. Heuser, Don W. Cleveland, and Ekaterina L. Grishchuk

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Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity, Pedro L. Martinez-Espinosa, Chengtao Yang, Vivian Gonzalez-Perez, Xiao-Ming Xia, and Christopher J. Lingle

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Lack of effect of risperidone on core autistic symptoms: data form a longitudinal study, Natasha Marrus, Heather Underwood-Riordan, Fellana Randall, Yi Zhang, and John N. Constantino

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Landscape of target: Guide homology effects on Cas9-mediated cleavage, Becky Xu Hua Fu, Loren L. Hansen, Karen L. Artiles, Michael L. Nonet, and Andrew Z. Fire

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Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response, Haroun Zangger, Asrat Hailu, Chantal Desponds, Lon-Fye Lye, Natalia S. Akopyants, Deborah E. Dobson, Catherine Ronet, Hashim Ghalib, Stephen M. Beverley, and Nicolas Fasel

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Levosimendan in critical illness: A literature review, Charalampos Pierrakos, Dimitrios Velissaris, Federico Franchi, Luigi Muzzi, Menelaos Karanikolas, and Sabino Scolletta

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Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element, Kinjal Majumder, Olivia I. Koues, Elizabeth A. W. Chan, Katherine E. Kyle, Julie E. Horowitz, Katherine Yang-Iott, Craig H. Bassing, Ichiro Taniuchi, Michael S. Krangel, and Eugene M. Oltz

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Listening effort and accented speech, Kristen J. Van Engen and Jonathan E. Peelle

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Localizing ECoG electrodes on the cortical anatomy without post-implantation imaging, Disha Gupta, N. Jeremy Hill, Matthew A. Adamo, Anthony Ritaccio, and Gerwin Schalk

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Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells, Sarah H. McBride, Jennifer A. McKenzie, Bronwyn S. Bedrick, Paige Kuhlmann, Jill D. Pasteris, Vicki Rosen, and Matthew J. Silva

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Long-term outcomes following a single corticosteroid injection for trigger finger, Robert D. Wojahn, Nicholas C. Foeger, Richard H. Gelberman, and Ryan P. Calfee

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Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC, Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Brian A. Van Tine, Matthew J. Ellis, Andreas Herrlich, and Loren S. Michel

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Loureirin B, an essential component of Sanguis Draxonis, inhibits Kv1.3 channel and suppresses cytokine release from Jurkat T cells, Shijin Yin, Qinglan Hu, Jialie Luo, Yuxin Li, Chunlan Lu, Xuan Chen, and Hongzhen Hu

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L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection, Lauren E. Deady, Elizabeth M. Todd, Chris G. Davis, Julie Y. Zhou, Nermina Topcagic, Brian T. Edelson, Thomas W. Ferkol, Megan A. Cooper, Jared T. Muenzer, and Sharon Celeste Morley

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Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis, Marcia Nascimento, Stanley C. Huang, Amber Smith, Bart Everts, Wing Lam, Elizabeth Bassity, Emmanuel L. Gautier, Gwendalyn J. Randolph, and Edward J. Pearce

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Macrolides are associated with a better survival rate in patients hospitalized with community-acquired but not healthcare-associated pneumonia, Colleen McEvoy, Scott T. Micek, Richard M. Reichley, Jason Kan, Alex Hoban, Justin Hoffmann, Andrew F. Shorr, and Marin H. Kollef

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Management of anticoagulant-related intracranial hemorrhage: An evidence-based review, Bappaditya Ray and Salah G. Keyrouz

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Mast cell leukemia with prolonged survival on PKC412/midostaurin, Xiangdong Xu, Friederike H. Kreisel, John L. Frater, and Anjum Hassan

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Mechanistically distinct mouse models for CRX-associated retinopathy, Nicholas M. Tran, Alan Zhang, Xiaodong Zhang, Julie B. Huecker, Anne K. Hennig, and Shiming Chen

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Memory accumulation mechanisms in human cortex are independent of motor intentions, Carlo Sestieri, Annalisa Tosoni, Valeria Mignogna, Mark P. McAvoy, Gordon L. Shulman, Maurizio Corbetta, and Gian Luca Romani

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Memory regulatory T cells reside in human skin, Bryan A. Anthony, Robert Sanchez Rodriguez, Mariela L. Pauli, Isaac M. Neuhaus, Siegrid S. Yu, Sarah T. Arron, Hobart W. Harris, Sara Hsin-Yi Yang, Francis M. Sverdrup, Elisabeth Krow-Lucal, Tippi C. MacKenzie, David S. Johnson, Everett H. Meyer, Andrea Löhr, and et al.

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Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes, Ping An, Aldi Kraja, Michael A. Province, Ingrid B. Borecki, and et al.

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Metabolic control of dendritic cell activation and function: Recent advances and clinical implications, Bart Everts and Edward J. Pearce

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Metagenomic analysis of double-stranded DNA viruses in healthy adults, Kristine M. Wylie, Kathie A. Mihindukulasuriya, Yanjiao Zhou, Erica Sodergren, Gregory A. Storch, and George M. Weinstock

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Metastasis occurring eleven years after diagnosis of human papilloma virus-related oropharyngeal squamous cell carcinoma, Jessica Ley, Tanya Wildes, Samir El-Mofty, and Douglas Adkins

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Methodological challenges and solutions in auditory functional magnetic resonance imaging, Jonathan E. Peelle

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Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation, Jeffrey J. Werner, Marcelo L. Garcia, Sarah D. Perkins, Kevin E. Yarasheski, Samuel R. Smith, Brian D. Muegge, Frank J. Stadermann, Christopher M. DeRito, Christine Floss, Eugene L. Madsen, Jeffrey I. Gordon, and Largus T. Angenent

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Microelectrode arrays and the use of PEG-functionalized diblock copolymer coatings, Sakshi Uppal, Matthew D. Graaf, and Kevin D. Moeller

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MicroRNAs in the stressed heart: Sorting the signal from the noise, Scot J. Matkovich

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Mindfulness may both moderate and mediate the effect of physical fitness on cardiovascular responses to stress: A speculative hypothesis, Marcelo M.P. Demarzo, Jesus Montero-Marin, Phyllis K. Stein, Ausias Cebolla, Jaime G. Provinciale, and Javier Garcia-Campayo

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miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain, Dominique Cannella, Marie-Pierre Brenier-Pinchart, Laurence Braun, Jason M. van Rooyen, Alexandre Bougdour, Olivier Bastien, Michael S. Behnke, Rose-Laurence Curt, Aurelie Curt, Jeroen P.J. Saeij, L. David Sibley, Herve Pelloux, and Mohamed-Ali Hakimi

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Missed opportunities: Racial and neighborhood socioeconomic disparities in emergency colorectal cancer diagnosis and surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, and Mario Schootman

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Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons, Daniel W. Summers, Aaron DiAntonio, and Jeffrey Milbrandt

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Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila, Yun Chen, Megan Sparks, Poonam Bhandari, Scot J. Matkovich, and Gerald W. Dorn