Submissions from 2014
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion, Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, and Brian N. Finck
Mobster: Accurate detection of mobile element insertions in next generation sequencing data, Djie Tjwan Thung, Joep de Ligt, Lisenka EM Vissers, Marloes Steehouwer, Mark Kroon, Petra de Vries, Eline P. Slagboom, Kai Ye, Joris A. Veltman, and Jayne Y. Hehir-Kwa
MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice, Arun Gupta, Clayton R. Hunt, Nobuo Horikoshi, Raj K. Pandita, Tej K. Pandita, and et al
Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States, Jennifer M. Adams-Haduch, Ezenwa O. Onuoha, Tatiana Bogdanovich, Guo-Bao Tian, Jonas Marschall, Carl M. Urban, Brad J. Spellberg, Diane Rhee, Diane C. Halstead, Anthony W. Pasculle, and Yohei Doi
Molecularly targeted therapies in multiple myeloma, Pilar de la Puente, Barbara Muz, Feda Azab, Micah Luderer, and Abdel Kareem Azab
Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene, Igor P. Dmitriev, Elena A. Kashentseva, Walter J. Akers, Samuel Achilefu, David T. Curiel, and et al
Morphologic and molecular evaluation of Chlamydia trachomatis growth in human endocervix reveals distinct growth patterns, Wandy L. Beatty and et al
Motherhood, psychological risks, and resources in relation to alcohol use disorder: Are there differences between black and white women?, Sundari Balan, Gregory Widner, Hsing-Jung Chen, Darrell Hudson, Sarah Gehlert, and Rumi Kato Price
MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage, Marielle C. Gold, James E. McLaren, Joseph A. Reisetter, Sue Smyk-Pearson, Kristin Ladell, Gwendolyn M. Swarbrick, Yik Y L Yu, Ted H. Hansen, Ole Lund, Morten Nielsen, Bram Gerritsen, Can Kesmir, John J. Miles, Deborah A. Lewinsohn, David A. Price, and David M. Lewinsohn
Multicenter evaluation of computer automated versus traditional surveillance of hospital-acquired bloodstream infections, Michael Y. Lin, Keith F. Woeltje, Yosef M. Khan, Bala Hota, Joshua A. Doherty, Tara B. Borlawsky, Kurt Stevenson, Scott K. Fridkin, Robert A. Weinstein, and William E. Trick
Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: A retrospective cohort study, Marya D. Zilberberg, Andrew F. Shorr, Scott T. Micek, Cristina Vazquez-Guillamet, and Marin H. Kollef
Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion, May M. Paing and Niraj H. Tolia
Multiple dietary supplements do not affect metabolic and cardio-vascular health, Andreea Soare, Edward P. Weiss, John O. Holloszy, and Luigi Fontana
Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection, David M. Alvarado, Ping Yang, Todd E. Druley, Michael Lovett, and Christina A. Gurnett
Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors, Gabriel A. Bien-Willner and Robi D. Mitra
Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma, Thomas M. Bennett, Donna S. Mackay, Carla J. Siegfried, and Alan Shiels
Mycobacterium ulcerans infection imported from Australia to Missouri, USA, 2012, Benjamin Stuart Thomas, Thomas C. Bailey, Julu Bhatnagar, Jana M. Ritter, Brian D. Emery, Omar W. Jassim, Ian Kerst Hornstra, and Sarah L. George
Nanoparticle incorporation of melittin reduces sperm and vaginal epithelium cytotoxicity, Andrew P. Jallouk, Kelle H. Moley, Kenan Omurtag, Grace Hu, Gregory M. Lanza, Samuel A. Wickline, and Joshua L. Hood
Natural antisense transcripts regulate the neuronal stress response and excitability, Xingguo Zheng, Vera Valakh, Aaron DiAntonio, and Yehuda Ben-Shahar
Nephrotic syndrome in acute promyelocytic leukemia, Borhan Moradveisi, Armin Rashidi, Samin Alavi, and Alireza Eskandarifar
Nerve transfers to restore upper extremity function: A paradigm shift, Amy M. Moore
Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis, Matthew R. Brier, Jewell B. Thomas, and Beau M. Ances
Network inefficiencies in autism spectrum disorder at 24 months, J R. Pruett, K Botteron, R McKinstry, and et al
Network-mediated encoding of circadian time: The suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back, Marco Brancaccio, Ryosuke Enoki, Cristina N. Mazuski, Jeff Jones, Jennifer A. Evans, and Abdelhalim Azzi
Neural activation associated with the cognitive emotion regulation of sadness in healthy children, Andy C. Belden, Joan L. Luby, David Pagliaccio, and Deanna M. Barch
Neurologic abnormalities in mouse models of the lysosomal storage disorders mucolipidosis II and mucolipidosis III γ, Rachel A. Idol, David F. Wozniak, Hideji Fujiwara, Carla M. Yuede, Daniel S. Ory, Stuart Kornfeld, and Peter Vogel
Neuronal activity regulates extracellular tau in vivo, Kaoru Yamada, Jerrah K. Holth, Fan Liao, Floy R. Stewart, Thomas E. Mahan, Hong Jiang, John R. Cirrito, Tirth K. Patel, Katja Hochgräfe, Eva-Maria Mandelkow, and David M. Holtzman
New concepts in breast cancer genomics and genetics, Rodrigo Goncalves, Wayne A. Warner, Jingqin Luo, and Matthew J. Ellis
NextGen sequencing reveals short double crossovers contribute disproportionately to genetic diversity in Toxoplasma gondii, Asis Khan, Jahangheer S. Shaik, Michael Behnke, Qiuling Wang, Jitender P. Dubey, Hernan A. Lorenzi, James W. Ajioka, Benjamin M. Rosenthal, and L. David Sibley
Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner, Cynthia Garcia and David H. Gutmann
NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection, Caihong Wang, Xuejun Yuan, Emily Ma, Graziella R. Mendonsa, Theo R. Plantinga, Lambertus A. Kiemeney, Sita H. Vermeulen, and Indira U. Mysorekar
Noninvasive imaging of focal atherosclerotic lesions using fluorescence molecular tomography, Dolonchampa Maji, Metasebya Solomon, Annie Nguyen, Richard A. Pierce, Pamela K. Woodard, Walter J. Akers, Samuel Achilefu, Joseph P. Culver, Dana R. Abendschein, and Monica Shokeen
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index, Felicia Gomez, Ingrid B. Borecki, and et al
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis, Andrew C. Heath and Pamela A. F. Madden
Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3, Gunjal Garg, Jesse Gibbs, Brian Belt, Matthew A. Powell, David G. Mutch, Peter Goedegebuure, Lynne Collins, David Piwnica-Worms, William G. Hawkins, and Dirk Spitzer
Nutraceutical intervention improves older adults' cognitive functioning, Brent J. Small, Kerri S. Rawson, Christina Martin, Sarah L. Eisel, Cyndy D. Sanberg, Cathy L. McEvoy, Paul R. Sanberg, Douglas Shytle, Jun Tan, and Paula C. Bickford
Occupational sitting and weight status in a diverse sample of employees in Midwest metropolitan cities, 2012–2013, Lin Yang, J. Aaron Hipp, Christine M. Marx, and Ross C. Brownson
Opposing brain differences in 16p11.2 deletion and duplication carriers, Abid Y. Qureshi, Sophia Mueller, Abraham Z. Snyder, Pratik Mukherjee, Jeffrey I. Berman, Timothy P. L. Roberts, Srikantan S. Nagarajan, John E. Spiro, Wendy K. Chung, Elliott H. Sherr, and Randy L. Buckner
Optimal body weight for health and longevity: Bridging basic, clinical, and population research, Luigi Fontana and Frank B. Hu
Oral contraceptive use and mortality after 36 years of follow-up in the Nurses' Health Study: Prospective cohort study, Brittany M. Charlton, Janet W. Rich-Edwards, Graham A. Colditz, Stacey A. Missmer, Bernard A. Rosner, Susan E. Hankinson, Frank E. Speizer, and Karin B. Michels
Organizing knowledge to enable personalization of medicine in cancer, Benjamin M. Good, Benjamin J. Ainscough, Josh F. McMichael, Andrew I. Su, and Obi L. Griffith
Origin and consequences of the relationship between protein mean and variance, Francesco Luigi Massimo Vallania, Marc Sherman, Zane Goodwin, Ilaria Mogno, Barak Alon Cohen, and Robi David Mitra
Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice, Jianquan Chen, Yu Shi, Jenna Regan, Kannan Karuppaiah, David M. Ornitz, and Fanxin Long
Outcome for children with metastatic solid tumors over the last four decades, Stephanie M. Perkins, Eric T. Shinohara, Todd DeWees, and Haydar Frangoul
Outcome of all-inside second-generation meniscal repair: Minimum five-year follow-up, Ljiljana Bogunovic, Lisa M. Kruse, Amanda K. Haas, Laura J. Huston, and Rick W. Wright
Outpatient parenteral antimicrobial therapy practices among adult infectious disease physicians, Michael A. Lane, Jonas Marschall, Susan E. Beekman, Philip M. Polgreen, Ritu Banerjee, Adam L. Hersh, and Hilary M. Babcock
Over-expression of TRESK K(+) channels reduces the excitability of trigeminal ganglion nociceptors, Zhaohua Guo and Yu-Qing Cao
Overview of gene structure in C. elegans, John Spieth, Daniel Lawson, Paul Davis, Gary Williams, and Kevin Howe
p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche, Marcus Watkins, Roberto Civitelli, and et al
Parallels between cancer and infectious disease, Richard S. Hotchkiss and Lyle L. Moldawer
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii, Christopher D. Dupont, David A. Christian, Elizabeth M. Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A. Koshy, Sagie Wagage, Morgan A. Reuter, L. David Sibley, Michael R. Betts, and Christopher A. Hunter
Participants’ perceptions of a group based program incorporating hands-on meal preparation and pedometer-based self-monitoring in type 2 diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, and Deborah Da Costa
Pathogenic adaptations to host-derived antibacterial copper, Kaveri S. Chaturvedi and Jeffrey P. Henderson
Pathogen reduction in human plasma using an ultrashort pulsed laser, Shaw-Wei D. Tsen, David H. Kingsley, Karen Kibler, Bert Jacobs, Sara Sizemore, Sara M. Vaiana, Jeanne Anderson, Kong-Thon Tsen, and Samuel Achilefu
Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors, Terence T. Sio, Kenneth Chang, Ritujith Jayakrishnan, Difu Wu, Mary Politi, Dominique Malacarne, James Saletnik, and Maureen Chung
Patient-controlled epidural Levobupicvacaine with or without Fentanyl for post-cesarean section pain relief, Shin-Yan Chen, Feng-Lin Liu, Yih-Giun Cherng, Shou-Zen Fan, Barbara L. Leighton, Hung-Chi Chang, and Li-Kuei Chen
Patients with pathologically proven renal disease have similar declines in renal function following robot-assisted partial nephrectomy, Jonathan M. Mobley, Eric H. Kim, Jeffrey A. Larson, Robert S. Figenshau, Joel M. Vetter, Michael H. Johnson, and Sam B. Bhayani
Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism, Yu Zhou and Christopher J. Lingle
Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly, Pardeep Kumar, Christian Heiss, Felipe H. Santiago-Tirado, Ian Black, Parastoo Azadi, and Tamara L. Doering
PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells, Michael D. Brooks, Erin Jackson, Nicole M. Warrington, Jingqin Luo, Jason T. Forys, Sara Taylor, Diane D. Mao, Jeffrey R. Leonard, Albert H. Kim, David Piwnica-Worms, Robi D. Mitra, and Joshua B. Rubin
Peptidergic cell-specific synaptotagmins in Drosophila: Localization to dense-core granules and regulation by the bHLH protein dimmed, Dongkook Park, Peiyao Li, Adish Dani, and Paul H. Taghert
Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis, Hui-fang Zhou, Huimin Yan, Hua Pan, Kirk K. Hou, Antonina Akk, Luke E. Springer, Ying Hu, J. Stacy Allen, Samuel A. Wickline, and Christine T.N. Pham
Perceived benefits and challenges of coordinated approaches to chronic disease prevention in state health departments, Peg Allen, Sonia Sequeria, Leslie Best, Ellen Jones, Elizabeth A. Baker, and Ross C. Brownson
Pervasive transcription of a herpesvirus genome generates functionally important RNAs, Susan P. Canny, Tiffany A. Reese, L. Steven Johnson, Xin Zhang, Amal Kambal, Erning Duan, Catherine Y. Liu, and Herbert W. Virgin
Pharmacokinetic changes and dosing modification of aminoglycosides in critically ill obese patients: A literature review, Dimitrios Velissaris, Vasilios Karamouzos, Markos Marangos, Charalampos Pierrakos, and Menelaos Karanikolas
Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect, Jaebok Choi, Matthew L. Cooper, Bader Alahmari, Julie Ritchey, Lynne Collins, Matthew Holt, and John F. DiPersio
Phenotypic and genotypic analysis of Clostridium difficile isolates: A single-center study, Yanjiao Zhou, Carey-Ann D. Burnham, Tiffany Hink, Lei Chen, Nurmohammad Shaikh, Aye Wollam, Erica Sodergren, George M. Weinstock, Phillip I. Tarr, and Erik R. Dubberke
Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers, Chong-kui Sun, Fan Zhang, Tao Xiang, Qianming Chen, Tej K. Pandita, Yuping Huang, Mickey C T Hu, and Qin Yang
Photo quiz: A 58-year-old female with altered mental status, Morgan A. Pence and Carey-Ann D. Burnham
Phylogenomics and the dynamic genome evolution of the genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, and Michael J. Stanhope
PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma, Nina D. Wagner-Johnston and et al
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli, Sarah E. Greene, Jerome S. Pinkner, Erik Chorell, Karen W. Dodson, Carrie L. Shaffer, Matt S. Conover, Jonathan Livny, Maria Hadjifrangiskou, Fredrik Almqvist, and Scott J. Hultgren
Plant-associated symbiotic Burkholderia species lack hallmark strategies required in mammalian pathogenesis, Annette A. Angus, Christina M. Agapakis, Stephanie Fong, Shailaja Yerrapragada, Paulina Estrad-de los Santos, Paul Yang, Nannie Song, Stephanie Kano, Jesus Caballero-Mellado, Sergio M. de Faria, Felix D. Dakora, George Weinstock, and Ann M. Hirsch
Population genetic analyses of Helicobacter pylori isolates from Gambian adults and children, Ousman Secka, Yoshan Moodley, Martin Antonio, Douglas E. Berg, Mary Tapgun, Robert Walton, Archibald Worwui, Vivat Thomas, Tumani Corrah, Julian E. Thomas, and Richard A. Adegbola
Positron emission tomographic imaging of Copper 64- and Gallium 68-labeled chelator conjugates of the somatostatin agonist Tyr3-octreotate, Jessie R. Nedrow, Alexander G. White, Jalpa Modi, Kim Nguyen, Albert J. Chang, and Carolyn J. Anderson
Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem, Ji-Young Kim, Ana Kim, Zhong-Qiu Zhou, Xian-Yu Liu, and Zhou-Feng Chen
Potent Dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement, Melissa A. Edeling, S. Kyle Austin, Bimmi Shrestha, Kimberly A. Dowd, Swati Mukherjee, Christopher A. Nelson, Syd Johnson, Manu N. Mabila, Elizabeth A. Christian, Joseph Rucker, Theodore C. Pierson, Michael S. Diamond, and Daved H. Fremont
Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis de Lecea, and David M. Holtzman
Practical barriers and ethical challenges in genetic data sharing, Rob Culverhouse and et al
Predicting response and survival in chemotherapy-treated triple-negative breast cancer, Matthew J. Ellis, E. Mardis, Tammi L. Vickery, and et al
Predicting structure and stability for RNA complexes with intermolecular loop–loop base-pairing, Song Cao, Xiaojun Xu, and Shijie Chen
Predictors of hospital mortality among septic ICU patients with Acinetobacter spp. bacteremia: A cohort study, Andrew F. Shorr, Marya D. Zilberberg, Scott T. Micek, and Marin H. Kollef
Preliminary evaluation of urinary soluble Met as a Biomarker for urothelial carcinoma of the bladder, Robert L. Grubb III and et al
Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation, Robert Strunk and et al
Prevalence, correlates, and prognosis of peripheral artery disease in rural ecuador-rationale, protocol, and phase I results of a population-based survey: an atahualpa project-ancillary study, Oscar H. Del Brutto, Mark J. Sedler, Robertino M. Mera, Pablo R. Castillo, Elizabeth H. Cusick, Jadry A. Gruen, Kelsie J. Phelan, Victor J. Del Brutto, Mauricio Zambrano, and David L. Brown
Prevalence of cigarette advertising and other promotional strategies at the point of sale in St Louis, Missouri: Analysis by store type and distance from a school, Joaquin Barnoya, Graham Colditz, Sarah Moreland-Russell, Julianne Cyr, Doneisha Snider, and Mario Schootman
Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus, Christopher D. Doern, Sean T. Nguyen, Folashade Afolabi, and Carey-Ann D. Burnham
Progress in pediatric kidney transplantation, Jodi M. Smith and Vikas R. Dharnidharka
Propofol and sevoflurane induce distinct burst suppression patterns in rats, Jonathan D. Kenny, M. Brandon Westover, ShiNung Ching, Emery N. Brown, and Ken Solt
Proteasome inhibitors activate autophagy involving inhibition of PI3K-Akt-mTOR pathway as an anti-oxidation defense in human RPE cells, Bingrong Tang, Jingjing Cai, Lin Sun, Yiping Li, Jia Qu, Barbara Joy Snider, and Shengzhou Wu
Provision of no-cost, long-acting contraception and teenage pregnancy., Gina M. Secura, Tessa Madden, Colleen McNicholas, Jennifer Mullersman, Christina M. Buckel, Qiuhong Zhao, and Jeffrey F. Peipert
Psychiatric correlates of snuff and chewing tobacco use, Qiang Fu, Michael G. Vaughn, Li-Tzy Wu, and Andrew C. Heath
Public perception regarding anterior cruciate ligament reconstruction, Matthew J. Matava, Daniel R. Howard, Landon Polakof, and Robert H. Brophy
Pulmonary phaeohyphomycosis caused by phaeoacremonium in a kidney transplant recipient: Successful treatment with posaconazole, Saivaralaxmi Monaganti, Carlos A Q Santos, Andrea Markwardt, Morgan A. Pence, and Daniel C. Brennan
Quantitative evaluation of atlas-based highdensity diffuse optical tomography for imaging of the human visual cortex, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani
Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states, Nadine Ehmann, Sebastian van de Linde, Amit Alon, Dmitrij Ljaschenko, Xi Zhen Keung, Thorge Holm, Annika Rings, Aaron DiAntonio, Stefan Hallermann, Uri Ashery, Manfred Heckmann, Markus Sauer, and Robert J. Kittel
Rab5 isoforms orchestrate a ‘‘Division of Labor’’ in the endocytic network; Rab5C modulates Rac-mediated cell motility, Pin-I Chen, Kristine Schauer, Chen Kong, Andrew R. Harding, Bruno Goud, and Philip D. Stahl
Radial symmetry in a chimeric glutamate receptor pore, Timothy J. Wilding, Melany N. Lopez, and James E. Huettner
Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein, Xiang Zhang, Hongjun Jin, Prashanth K. Padakanti, Junfeng Li, Hao Yang, Jinda Fan, Robert H. Mach, Paul Kotzbauer, and Zhade Tu
Rare variant analysis of blood pressure phenotypes in the Genetic Analysis Workshop 18 whole genome sequencing data using sequence kernel association test, Cates Mallaney and Yun Ju Sung
