Submissions from 2012
Data sharing in neuroimaging research, Jean-Baptiste Poline, Janis L. Breeze, Satrajit Ghosh, Krzysztof Gorgolewski, Yaroslav O. Halchenko, Michael Hanke, Christian Haselgrove, Karl G. Helmer, David B. Keator, Daniel S. Marcus, Russell A. Poldrack, Yannick Schwartz, John Ashburner, and David N. Kennedy
Deciphering a global network of functionally associated post-translational modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera van Noort, and Peer Bork
Deconvoluting mTOR biology, Jason D. Weber and David H. Gutmann
Decreased functional connectivity between the amygdala and the left ventral prefrontal cortex in treatment-naive patients with major depressive disorder: A resting-state functional magnetic resonance imaging study, Y. Tang, L. Kong, F. Womer, W. Jiang, Y. Cao, L. Ren, J. Wang, G. Fan, H. P. Blumberg, K. Xu, and F. Wang
Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector, Briana Jill Williams, Shilpa Bhatia, Lisa K. Adams, Susan Boling, Jennifer L. Carroll, Xiao-Lin Li, Donna L. Rogers, Nikolay Korokhov, Imre Kovesdi, Alexander V. Pereboev, David T. Curiel, and Michael Mathis
Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy, Kenneth G. Nepple, Gurdarshan S. Sandhu, Craig G. Rogers, Mohamad E. Allaf, Jihad H. Kaouk, Robert S. Figenshau, Michael D. Stifelman, and Sam B. Bhayani
Development of a new humanized mouse model to study acute inflammatory arthritis, Alexander V. Misharin, G K. Haines, Shawn Rose, Angelical K. Gierut, Richard S. Hotchkiss, and Harris Perlman
Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates, Marc R. Hammerman
Diagnosing symptomatic HIV-associated neurocognitive disorders: Self-report versus performance-based assessment of everyday functioning, David B. Clifford and et al
Diazoxide maintains human myocyte volume homeostasis during stress, Sara K. Maffit, Angela D. Sellitto, Ashraf S. Al-Dadah, Richard B. Schuessler, Ralph J. Damiano Jr., and Jennifer S. Lawton
Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background, Sharon V. Kawakami-Schulz, Angela M. Verdoni, Shannon G. Sattler, Akihiro Ikeda, and Sakae Ikeda
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, and Brenda L. Fredericksen
Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals, Devon C. Crawford, Xiaoping Jiang, Amanda Taylor, Krista L. Moulder, and Steven Mennerick
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal, Sung-Ho Huh, Jennifer Jones, Mark E. Warchol, and David M. Ornitz
Distinct repeat motifs at the C-terminal region of CagA of Helicobacter pylori strains isolated from diseased patients and asymptomatic individuals in West Bengal, India, Santanu Chattopadhyay, Rajashree Patra, Raghunath Chatterjee, Ronita De, Jawed Alam, T. Ramamurthy, Abhijit Chowdhury, G. Balakrish Nair, Douglas E. Berg, and Asish K. Mukhopadhyay
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection, Maria Kostakioti, Maria Hadjifrangiskou, Corinne K. Cusumano, Thomas J. Hannan, James W. Janetka, and Scott J. Hultgren
DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, and Jing Zhang
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, and Judith L. Campbell
Early brain vulnerability in Wolfram syndrome, Tamara Hershey, Heather M. Lugar, Joshua S. Shimony, Jerrel Rutlin, Jonathan M. Koller, Dana C. Perantie, Alex R. Paciorkowski, Sarah A. Eisenstein, M. Alan Permutt, and Washington University Wolfram Study Group
Early presentation of gait impairment in Wolfram Syndrome, Kristen A. Pickett, Ryan P. Duncan, James Hoekel, Bess Marshall, Tamara Hershey, Gammon M. Earhart, and Washington University Wolfram Study Group
Economic impact of ventilator-associated pneumonia in a large matched cohort, Marin H. Kollef, Cindy W. Hamilton, and Frank R. Ernst
Effectiveness of long-acting reversible contraception, Brooke Winner, Jeffrey F. Peipert, Quihong Zhao, Christina Buckel, Tessa Madden, Jenifer E. Allsworth, and Gina M. Secura
Effect of inhaled glucocorticoids in childhood on adult height, H. William Kelly, Alice L. Sternberg, Rachel Lescher, Anne L. Fuhlbrigge, Paul Williams, Robert S. Zeiger, Hengameh H. Raissy, Mark L. Van Natta, James Tonascia, and Robert C. Strunk
Effect of (Neo)adjuvant zoledronic acid on disease-free and overall survival in clinical stage II/III breast cancer, Rebecca L. Aft, Michael J. Naughton, Kathryn M. Trinkaus, and Katherine N. Weilbaecher
Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult female worms in vivo, Ramakrishna U. Rao, Yuefang Huang, Sahar Abubucker, Michael Heinz, Seth D. Crosby, Makedonka Mitreva, and Gary J. Weil
Electrophysiological correlates of stimulus-driven reorienting deficits after interference with right parietal cortex during a spatial attention task: A TMS-EEG study, Paolo Capotosto, Maurizio Corbetta, Gian Luca Romani, and Claudio Babiloni
Enhanced surgical site infection surveillance following hysterectomy, vascular, and colorectal surgery, Deborah S. Yokoe, Yosef Khan, Margaret A. Olsen, David C. Hooper, Maurice Greenbaum, Johanna Vostok, Julie Lankiewicz, Victoria J. Fraser, and Kurt B. Stevenson
Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death, Xiucui Ma, Rebecca J. Godar, Haiyan Liu, and Abhinav Diwan
Environmental influences predominate in remission from alcohol use disorder in young adult twins, V. V. McCutcheon, J. D. Grant, A. C. Heath, K. K. Bucholz, C. E. Sartor, E. C. Nelson, P. A F Madden, and N. G. Martin
Enzyme-replacement therapy in life-threatening hypophosphatasia, Michael P. Whyte, William H. McAlister, and et al
Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages, Nicole S. Maloney, Larissa B. Thackray, Gautam Goel, Seungmin Hwang, Erning Duan, Punit Vachharajani, Ramnik Xavier, and Herbert W. Virgin
Estimating the heritability of reporting stressful life events captured by common genetic variants, J. P. Rice and et al
Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA, Baozhou Sun, Dharanipathy Rangaraj, Sunita Boddu, Murty Goddu, Deshan Yang, Geethpriya Palaniswaamy, Sridhar Yaddanapudi, Omar Wooten, and Sasa Mutic
Evidence for adult lung growth in humans, James P. Butler, Stephen H. Loring, Samuel Patz, Akira Tsuda, Dimitriy A. Yablonskiy, and Steven J. Mentzer
Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein, Rita PS Middelberg, Andrew C. Heath, Pamela AF Madden, Grant W. Montgomery, Nicholas G. Martin, and John B. Whitfield
Ewing's sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review, Waseem Khaliq, Mohammad Farshad Bahador, Thomas Nichols Laurence, Ronald Andrew Sapiente, James Sheridan Lewis Jr., and David Lee Graham
Exploration of chlamydial type III secretion system reconstitution in Escherichia coli, Xiaofeng Bao, Wandy L. Beatty, and Huizhou Fan
Exploring metazoan evolution through dynamic and holistic changes in protein families and domains, Zhengyuan Wang, Dante Zarlenga, John Martin, Sahar Abubucker, and Makedonka Mitreva
Exploring the DNA-recognition potential of homeodomains, Stephanie W. Chu, Marcus B. Noyes, Ryan G. Christensen, Brian G. Pierce, Lihua J. Zhu, Zhiping Weng, Gary D. Stormo, and Scot A. Wolfe
Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice, Lukas D. Wartman, John S. Welch, Geoffrey L. Uy, Jeffery M. Klco, Tamara Lamprecht, Nobish Varhese, Rakesh Nagarajan, and Timothy J. Ley
Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains, Celeste M. Karch, Amanda T. Jeng, Petra Nowotny, Janet Cady, Carlos Cruchaga, and Alison M. Goate
Expression of sialic acids and other nonulosonic acids in Leptospira, Jessica N. Ricaldi, Michael A. Matthias, Joseph M. Vinetz, and Amanda L. Lewis
Expression of stm4467-encoded arginine deiminase controlled by the stm4463 regulator contributes to salmonella enterica serovar typhimurium virulence, Younho Choi, Jeongjoon Choi, Eduardo A. Groisman, Dong-Hyun Kang, Dongwoo Shin, and Sangryeol Ryu
Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura, Dongyue Huang, Shuyang Li, Ajay Dhaka, Gina M. Story, and Yu-Qing Cao
Fast, sensitive discovery of conserved genome-wide motifs, NNamdi E. Ihuegbu, Gary D. Stormo, and Jeremy Buhler
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, and Edward J. Pearce
Fee-for-service as a business model of growing importance: the academic biobank experience, Sandra A. McDonald, Kara Sommerkamp, Maureen Egan-Palmer, Karen Kharasch, and Victoria Holtschlag
FGFR1 amplifi cation and the progression of non-invasive to invasive breast cancer, Alejandro A. Gru and D. Craig Allred
FGFR2 point mutations in 466 endometrioid endometrial tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features, Sara A. Byron, Michael Gartside, Matthew A. Powell, Candice L. Wellens, Feng Gao, David G. Mutch, Paul J. Goodfellow, and Pamela M. Pollock
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, and Alexander S. Krupnick
Frequent hospital readmissions for Clostridium difficile infection and the impact on estimates of hospital-associated C. difficile burden, Courtney R. Murphy, Taliser R. Avery, Erik R. Dubberke, and Susan S. Huang
Functional assessment of human coding mutations affecting skin pigmentation using zebrafish, Zurab R. Tsetskhladze, Victor A. Canfield, Khai C. Ang, Steven M. Wentzel, Katherine P. Reid, Arthur S. Berg, Stephen L. Johnson, Koichi Kawakami, and Keith C. Cheng
Functional consequences of cell type-restricted expression of laminin alpha-5 in mouse placental labyrinth and kidney glomerular capillaries, Sung Tae Kim, Tracy L. Adair-Kirk, Robert M. Senior, and Jefrey H. Miner
Functional consequences of subunit diversity in RNA polymerases II and V, Ek Han Tan, Todd Blevins, Thomas S. Ream, and Craig S. Pikaard
Functional relationships between lipid metabolism and liver regeneration, David A. Rudnick and Nicholas O. Davidson
Gastric bypass and banding equally improve insulin sensitivity and β cell function, David Bradley, Caterina Conte, Bettina Mittendorfer, J. Christopher Eagon, Esteban Varela, Elisa Fabbrini, Amalia Gastaldelli, Kari T. Chambers, Xiong Su, Adewole Okunade, Bruce W. Patterson, and Samuel Klein
Gastrointestinal lymphomas in a North American population: Clinicopathologic features from one major Central-Midwestern United States tertiary care medical center, Joshua Warrick, Jingqin Luo, Diane Robirds, Julie Branson, John L. Frater, Friederike Kreisel, Anjum Hassan, and TuDung T. Nguyen
Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesis, Dhananjay Yellajoshyula, Jong-won Lim, Dominic M. Thompson, Jacob S. Witt, Ethan S. Patterson, and Kristen L. Kroll
Genome-wide analysis of plant nat-siRNAs reveals insights into their distribution, biogenesis and function, Xiaoming Zhang, Jing Xia, Yifan E. Lii, Blanca E. Barrera-Figueroa, Xuefeng Zhou, Shang Gao, Lu Lu, Dongdong Niu, Zheng Chen, Christy Leung, Timothy Wong, Huiming Zhang, Jianhua Guo, Yi Li, Renyi Liu, Wanqi Liang, Jian-Kang Zhu, Weixiong Zhang, and Hailing Jin
Genome-wide association and functional follow-up reveals new loci for kidney function, Xiaoyi Gao, Mary Feitosa, Michael Province, Shamika Ketkar, Ingrid Borecki, and et al.
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA, Andrew C. Heath, Pamela A. F. Madden, and et al
Genome-wide meta-analyses of smoking behaviors in African Americans, Y. J. Sung, D. C. Rao, and et al
Glaucoma-induced degeneration of retinal ganglion cells prevented by hypoxic preconditioning: A model of glaucoma tolerance, Yanli Zhu, Lihong Zhang, Jimena F. Schmidt, and Jeffrey M. Gidday
GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle, Lauren Aerni-Flessner, Melissa Abi-Jaoude, Amanda Koening, Maria Payne, and Paul W. Hruz
Group VIB phospholipase A2 promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents, Shunzhong Bao, Haowei Song, Min Tan, Mary Wohltmann, Jack H. Ladenson, and John Turk
GSK-3β: A bifunctional role in cell death pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, and Dinesh Thotala
Guidelines for the use and interpretation of assays for monitoring autophagy, Abhinav Diwan, Seungmin Hwang, Indira Mysorekar, William A. Weiss, and et al
Health outcomes in patients using no-prescription online pharmacies to purchase prescription drugs, Theodore J. Cicero and Matthew S. Ellis
Health related quality of life outcomes for unresectable stage III or IV melanoma patients receiving ipilimumab treatment, Dennis A. Revicki, Alfons JM van den Eertwegh, Paul Lorigan, Celeste Lebbe, Gerald Linette, Christian H. Ottensmeier, Shima Safikhani, Marianne Messina, Alex Hoos, Samuel Wagner, and Srividya Kotapati
Heart rate variability changes at 2400 m altitude predicts acute mountain sickness on further ascent at 3000–4300 m altitudes, Heikki M. Karinen, Arja Uusitalo, Henri Vaha-Ypya, Mika Kahonen, Juha E. Peltonen, Phyllis K. Stein, Jari Viik, and Heikki O. Tikkanen
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis, Michelle A. Hurchla and Katherine N. Weilbaecher
Hepatitis C virus mediated changes in miRNA-449a modulates inflammatory biomarker YKL40 through components of the NOTCH signaling pathway, Nayan J. Sarma, Venkataswarup Tiriveedhi, Vijay Subramanian, Surendra Shenoy, Jeffrey S. Crippin, William C. Chapman, and Thalachallour Mohanakumar
High-throughput comparison of gene fitness among related bacteria, Rocio Canals, Xiao-Qin Xia, Catrina Fronick, Sandra W. Clifton, Brian MM Ahmer, Helene L. Andrews-Polymenis, Steffen Porwollik, and Michael McClelland
High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery, Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, and Michael J. Holtzman
Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness, Daniel Mamah, Michael P. Harms, Deanna Barch, Martin Styner, Jeffrey A. Lieberman, and Lei Wang
Hospital flood preparedness: A survey of 15 provinces in Central Thailand, Anucha Apisarnthanarak, Thana Khawcharoenporn, Keith F. Woeltje, and David K. Warren
Hospitalized cardiovascular events in patients with diabetic macular edema, Bao-Anh Nguyen-Khoa, Earl L. Goehring Jr., Winifred Werther, Anne E. Fung, Diana V. Do, Rajendra S. Apte, and Judith K. Jones
How do short-term changes at synapses fine-tune information processing?, Achim Klug, J. Gerard G. Borst, Bruce A. Carlson, Cornelia Kopp-Scheinpflug, Vitaly A. Klyachko, and Matthew A. Xu-Friedman
Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection, John P. Savaryn, Justin M. Reitsma, Tarin M. Bigley, Brian D. Halligan, Zhikang Xian, Dong Yu, and Scott S. Terhune
Human muscle-derived cell populations isolated by differential adhesion rates: Phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice, Steven M. Chirieleison, Joseph M. Feduska, Rebecca C. Schugar, Yuko Askew, and Bridget M. Deasy
Human polyomaviruses in children undergoing transplantation, United States, 2008-2010, Erica A. Siebrasse, Irma Bauer, Lori R. Holtz, Binh-minh Le, Sherry Lassa-Claxton, Charles Canter, Paul Hmiel, Shalini Shenoy, Stuart Sweet, Yumirle Turmelle, Ross Shepherd, and David Wang
Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint, Alexander P. Miceli, Anthony J. Saporita, and Jason D. Weber
Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts, Catherine Lozupone, Karoline Faust, Jeroen Raes, Jeremiah J. Faith, Daniel N. Frank, Jesse Zaneveld, Jeffrey I. Gordon, and Rob Knight
IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease, Keke C. Fairfax, Eyal Amiel, Irah L. King, Tori C. Freitas, Markus Mohrs, and Edward J. Pearce
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition, Yael G. Alevy, Anand C. Patel, Arthur G. Romero, Dhara A. Patel, Jennifer Tucker, William T. Roswit, Chantel A. Miller, Richard F. Heier, Derek E. Byers, Tom J. Brett, and Michael J. Holtzman
Image quality analysis of high-density diffuse optical tomography incorporating a subject-specific head model, Yuxuan Zhan, Adam T. Eggebrecht, Joseph P. Culver, and Hamid Dehghani
Imaging of poly(α-hydroxy-ester) scaffolds with X-ray phase-contrast microcomputed tomography, Alyssa A. Appel, Jeffery C. Larson, Sami Somo, Zhong Zhong, Patrick P. Spicer, Kurtis Kasper, Alfred B. Garson III, Adam M. Zysk, Antonios G. Mikos, Mark A. Anastasio, and Eric M. Brey
Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells, Barbara Drobits, Martin Holcmann, Nicole Amberg, Melissa Swiecki, Roland Grundtner, Martina Hammer, Marco Colonna, and Maria Sibilia
Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli, Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, Scott J. Hultgren, and Amanda L. Lewis
Immunohistochemical study of epiretinal membranes in patients with uveitis, Arsham Sheybani, George J. Harocopos, and P. Kumar Rao
Implementing automated surveillance for tracking Clostridium difficile infection at multiple healthcare facilities, Erik R. Dubberke, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Kurt B. Stevenson, Julie E. Mangino, Yosef M. Khan, Victoria J. Fraser, and Centers for Disease Control and Prevention Epicenter Program
Incorporating patient preference into the management of infertility in women with polycystic ovary syndrome, Ugochi C. Okoroafor and Emily S. Jungheim
Increased prevalence of anellovirus in pediatric patients with fever, Erin McElvania TeKippe, Kristine M. Wylie, Elena Deych, Erica Sodergren, George Weingstock, and Gregory A. Storch
Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection, Carly Page, Lindsay Golcohea, Krystal Matthews, Yong Zhang, Peter Klover, Michael J. Holtzman, Lothar Hennighausen, and Matthew Frieman
Influence of primary care physician availability and socioeconomic deprivation on breast cancer from 1988 to 2008: A spatio-temporal analysis, Lung-Chang Chien, Anjali D. Deshpande, Donna B. Jeffe, and Mario Schootman
Integrated signaling in developing lymphocytes: The role of DNA damage responses, Jeffrey J. Bednarski and Barry P. Sleckman
Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis, Leslie A. Weiss, Phillip G. Harrison, Bryce E. Nickels, Michael S. Glickman, Elizabeth A. Campbell, Seth A. Darst, and Christina L. Stallings
Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II, S.-W. Grace Cheng, Michael A. Kuzyk, Annie Moradian, Taka-Aki Ichu, Vicky C.-D. Chang, Jerry F. Tien, Sarah E. Vollett, Malachi Griffith, Marco A. Marra, and Gregg B. Morin
Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis, Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, and Ganes C. Sen
Intermuscular adipose tissue is muscle specific and associated with poor functional performance, Lori J. Tuttle, David R. Sinacore, and Michael J. Mueller
