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Submissions from 2012

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Intestinal adenocarcinoma arising in urinary conduits, Genevieve C. Moyer, Robert L. Grubb III, and Frank E. Johnson

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Intravital 2-photon imaging of leukocyte trafficking in beating heart, Wenjun Li, Ruben G. Nava, Alejandro C. Bribriesco, Bernd H. Zinselmeyer, Jessica H. Spahn, Andrew E. Gelman, Alexander S. Krupnick, Mark J. Miller, and Daniel Kreisel

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Intrinsic flexibility of snRNA hairpin loops facilitates protein binding, Michael Rau, W. T. Stump, and Kathleen B. Hall

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In vivo human apolipoprotein E isoform fractional turnover rates in the CNS, Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E. Yarasheski, Jennifer X. Wang, Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C. Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, and Randall J. Bateman

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Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA, Kathryn A. Knoop and Rodney D. Newberry

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Isolated short femur length on second-trimester sonography: A marker for fetal growth restriction and other adverse perinatal outcomes, Katherine R. Goetzinger, Alison G. Cahill, George A. Macones, and Anthony O. Odibo

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IS-seq: A novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes, Alejandro Reyes, Andrea Sandoval, Andrés Cubillos-Ruiz, Katherine E. Varley, Ivan Hernández-Neuta, Sofía Samper, Carlos Martín, María Jesús García, Viviana Ritacco, Lucelly López, Jaime Robledo, María Mercedes Zambrano, Robi D. Mitra, and Patricia Del Portillo

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It's all in the lens: Differences in views on obesity prevention between advocates and policy makers, Ellen Jones, Amy A. Eyler, Leah Nguyen, Jooyoung Kong, Ross C. Brownson, and Jessica H. Bailey

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Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis, Kevin W. Bruhn, Ron Birnbaum, Jacquelyn Haskell, Veena Vanchinathan, Stephanie Greger, Rupa Narayan, Pei-Lin Chang, Thu Anh Tran, Suzanne M. Hickerson, Stephen M. Beverley, Mary E. Wilson, and Noah Craft

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Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria, Patience B. Tetteh-Quarcoo, Christoph Q. Schmidt, Wai-Hong Tham, Richard Hauhart, Haydyn D T Mertens, Arthur Rowe, John P. Atkinson, Alan F. Cowman, J Alexandra Rowe, and Paul N. Barlow

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Lack of short-term effectiveness of rotating treadmill training on turning in people with mild-to-moderate Parkinson's disease and healthy older adults: A randomized, controlled study, Marie E. McNeely and Gammon M. Earhart

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Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background, Gerald Andriole Jr. and et al

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Lecture: New light on the role of claudins in the kidney, Jianghui Hou

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Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity, Maria Fernanda Laranjeira da Silva, Ricardo Andrade Zampieri, Sandra M. Muxel, Stephen M. Beverley, and Lucile M. Floeter-Winter

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Leishmania RNA virus: When the host pays the toll, Mary-Anne Hartley, Catherine Ronet, Haroun Zangger, Stephen M. Beverley, and Nicolas Fasel

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Lenalidomide after stem-cell transplantation for multiple myeloma, Ravi Viji and et al

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Ligand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutants, Mike Mueckler and Carol Makepeace

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LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina, David Razafsky, Nathaniel Blecher, Alexander Markov, P. J. Stewart-Hutchinson, and Didier Hodzic

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Listeriolysin O is strongly immunogenic independently of its cytotoxic activity, Javier A. Carrero, Hector Vivanco-Cid, and Emil R. Unanue

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LMP-420, a small molecular inhibitor of TNF-α, prolongs islet allograft survival by induction of suppressor of cytokine signaling-1: synergistic effect with cyclosporin-A, Nataraju Angaswamy, Naohiko Fukami, Venkataswarup Tiriveedhi, George J. Cianciolo, and T Mohanakumar

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Lysosomal membrane permeabilization is an early event in sigma-2 receptor ligand mediated cell death in pancreatic cancer, John R. Hornick, Suwanna Vangveravong, Dirk Spitzer, Carmen Abate, Francesco Berardi, Peter Goedegebuure, Robert H. Mach, and William G. Hawkins

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Marked response to VNS in a post-cingulotomy patient: Implications for the mechanism of action of VNS in TRD, Charles R. Conway, Mehret D. Gebretsadik, and Richard D. Bucholz

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Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling, Jacob M. Basak, Jungsu Kim, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Hong Jiang, Maia Parsadanian, Bruce W. Patterson, Randall J. Bateman, and David M. Holtzman

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Measurement properties of a novel survey to assess stages of organizational readiness for evidence-based interventions in community chronic disease prevention settings, Katherine A. Stamatakis, Amy McQueen, Carl Filler, Elizabeth Boland, Mariah Dreisinger, Ross C. Brownson, and Douglas A. Luke

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Measuring Granger causality between cortical regions from voxelwise fMRI BOLD signals with LASSO, Wei Tang, Steven L. Bressler, Chad M. Sylvester, Gordon L. Shulman, and Maurizio Corbetta

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Mechanisms of remodeling in asthmatic airways, Adrian Shifren, Chad Witt, Chandrika Christie, and Mario Castro

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Mechanistic characterization of the 5′-triphosphate-dependent activation of PKR: Lack of 5′-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD, Rebecca Toroney, Chelsea M. Hull, Joshua E. Sokoloski, and Philip C. Bevilacqua

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Medicaid expenditures on psychotropic medications for children in the child welfare system, Ramesh Raghavan, Derek S. Brown, Hope Thompson, Susan L. Ettner, Lisa M. Clements, and Whitney Key

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Meeting the need for regenerative therapies I: Target-based incidence and its relationship to U.S spending, productivity, and innovation, Nancy Parenteau, Janet Hardin-Young, William Shannon, Patrick Cantini, and Alan Russell

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Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: Study design and methods for pooling results of genetic epidemiological studies, Lynn Cornelius and et al

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Metabolic reconstruction for metagenomic data and Its application to the human microbiome, Sahar Abubucker, Nicola Segata, Johannes Goll, Alyxandria M. Schubert, Jacques Izard, Brandi L. Cantarel, Beltran Rodriguez-Mueller, Jeremy Zucker, Mathangi Thiagarajan, Bernard Henrissat, Owen White, Scott T. Kelly, Barbara Methe, Patrick D. Schloss, Dirk Gevers, Makedonka Mitreva, and Curtis Huttenhower

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Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception, Lara W. Crock, Kristina M. Stemler, David G. Song, Philip Abbosh, Sherri K. Vogt, Chang-Shen Qiu, H Henry Lai, Indira U. Mysorekar, and Robert W. Gereau IV

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MHC class I cross-presentation by dendritic cells counteracts viral immune evasion, Katrin Nopora, Caroline A. Bernhard, Christine Ried, Alejandro A. Castello, Kenneth M. Murphy, Peggy Marconi, Ulrich Koszinowski, and Thomas Brocker

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MicroRNAs are exported from malignant cells in customized particles, Jaime Palma, Scree C. Yaddanapudi, Lucy Pigati, Mallory A. Havens, Sarah Jeong, Geoffrey A. Weiner, Kristina Mary Ellen Weimer, Brittany Stern, Michelle L. Hastings, and Dominik M. Duelli

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Missing data methods for partial correlations, Gina M. D'Angelo, Jingqin Luo, and Chengjie Xiong

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Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus, Zhongmin Alex Ma, Zhengshan Zhao, and John Turk

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Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration, Albert L. Misko, Yo Sasaki, Elizabeth Tuck, Jeffrey Milbrandt, and Robert H. Baloh

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Mouse transgenesis in a single locus with independent regulation for multiple fluorophores, Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, and Nathaniel Heintz

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MTORC1 signaling and regulation of pancreatic β-cell mass, Manuel Blandino-Rosano, Angela Y. Chen, Joshua O. Scheys, Emilyn U. Alejandro, Aaron P. Gould, Tatyana Taranukha, Lynda Elghazi, Corentin Cras-Meneur, and Ernesto Bernal-Mizrachi

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Multi-Institutional experience with FOLFIRINOX in pancreatic adenocarcinoma, Parvin F. Peddi, Sam Lubner, Robert McWilliams, Benjamin R. Tan, Joel Picus, Steven M. Sorscher, Rama Suresh, A Craig Lockhart, Jian Wang, Christine Menias, Feng Gao, David Linehan, and Andrea Wang-Gilliam

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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder, M. L. Pergadia and et al

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Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress, Liang Chu, Mack Y. Su, Leonard B. Maggi Jr., Lan Lu, Chelsea Mullins, Seth Crosby, Gaofeng Huang, Wee Joo Chng, Ravi Vij, and Michael H. Tomasson

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Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, and Japanese Alzheimer's Disease Neuroimaging Initiative

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Multiscale forward electromagnetic model of uterine contractions during pregnancy, Patricio S. La Rosa, Hari Eswaran, Hubert Preissl, and Arye Nehorai

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Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study, Arpana Agrawal and et al

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MuSiC: Identifying mutational significance in cancer genomes, Nathan D. Dees, Qunyuan Zhang, Cyriac Kandoth, Michael C. Wendl, William Schierding, Daniel C. Kobolt, Thomas B. Mooney, Matthew B. Callaway, David Dooling, Elaine R. Mardis, Richard K. Wilson, and Li Ding

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Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions, Elisha D.O. Roberson, Christina A. Gurnett, Anne M. Bowcock, and et al

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Natural killer cell regulation by microRNAs in health and disease, Jeffrey W. Leong, Ryan P. Sullivan, and Todd A. Fehniger

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Nature and function of insulator protein binding sites in the Drosophila genome, Sarah C. R. Elgin and et al

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Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide, Lingbo Zhang, Kezheng Wang, Falin Zhao, Weiping Hu, Junjie Chen, Gregory M. Lanza, Baozhong Shen, and Bin Zhang

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Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data, John Martin, Sahar Abubucker, Esley Heizer, Christina M. Taylor, and Makedonka Mitreva

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Network analysis of corticocortical connections reveals ventral and dorsal processing streams in mouse visual cortex, Quanxin Wang, Olaf Sporns, and Andreas Burkhalter

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Neural correlates of prior expectations of motion in the lateral intraparietal and middle temporal areas, Vinod Rao, Gregory C. DeAngelis, and Lawrence H. Snyder

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Neural synchrony during response production and inhibition, Viktor Muller and Andrey P. Anokhin

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Neurofibromatosis type 1: Modeling CNS dysfunction, David H. Gutmann, Luis F. Parada, Alcino J. Silva, and Nancy Ratner

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No evidence of xenotropic murine leukemia virus-related virus transmission by blood transfusion from infected rhesus macaques, Dhanya K. Williams, Teresa A. Galvin, Yamei Gao, Christina O'Neill, Dustin Glasner, and Arifa S. Khan

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Novel bacterial taxa in the human microbiome, Kristine M. Wylie, Rebecca M. Truty, Thomas J. Sharpton, Kathie A. Mihindukulasuriya, Yanjiao Zhou, Hongyu Gao, Erica Sodergren, George M. Weinstock, and Katherine S. Pollard

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Novel BRAF alteration in a sporadic pilocytic astrocytoma, Sonika Dahiya, Jinsheng Yu, Aparna Kaul, Jeffrey R. Leonard, and David H. Gutmann

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Novel modeling of combinatorial miRNA targeting identifies SNP with potential role in bone density, Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V. Padit, Abha S. Bais, Michael Butterworth, Naftali Kaminski, Gary D. Stormo, Steffi Oesterreich, and Panayiotis V. Benos

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Observational Research in Childhood Infectious Diseases (ORChID): A dynamic birth cohort study, Stephen Bernard Lambert, Robert S. Ware, Anne L. Cook, Frances A. Maguire, David M. Whiley, Seweryn Bialasiewicz, Ian M. Mackay, David Wang, Theo P. Sloots, Michael D. Nissen, and Keith Grimwood

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Offspring ADHD as a risk factor for parental marital problems: Controls for genetic and environmental confounds, Alice C. Schermerhorn, Brian M. D'Onofrio, Wendy S. Slutske, Robert E. Emery, Eric Turkheimer, K. Paige Harden, Andrew C. Heath, and Nicholas G. Martin

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Optimizing global health experiences in emergency medicine residency programs: A consensus statement from the Council of Emergency Medicine Residency Directors 2011 Academic Assembly global health specialty track, Janis P. Tupesis, Christine Babcock, Doug Char, Kumar Alagappan, Braden Hexom, and G. B. Kapur

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Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities, John Martin, Sean Sykes, Sarah Young, Karthik Kota, Ravi Sanka, Nihar Sheth, Joshua Orvis, Erica Sodergren, Zhengyuan Wang, George M. Weinstock, and Makedonka Mitreva

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Organization of Vomeronasal Sensory Coding Revealed by Fast Volumetric Calcium Imaging, Diwakar Turaga and Timothy E. Holy

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Overcoming phase 1 delays: The critical component of obstetric fistula prevention programs in resource-poor countries, L. Lewis Wall

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PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection, Qiang Wang, Shijian Zhang, Hongbing Jiang, Jinlan Wang, Leiyun Weng, Yingying Mao, Satoshi Sekiguchi, Fumihiko Yasui, Michinori Kohara, Philippe Buchy, Vincent Deubel, Ke Xu, Bing Sun, and Tetsuya Toyoda

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PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers, Matthew J. Ellis and et al

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Papillary renal carcinoma presenting as a cancer of unknown primary (CUP) and diagnosed through gene expression profiling, Steven M. Sorscher and Frank Anthony Greco

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Paragonimus kellicotti Fluke infections in Missouri, USA, Michael A. Lane, Mary C. Barsanti, Carlos A. Santos, Michael Yeung, Sam J. Lubner, and Gary J. Weil

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Partner randomized controlled trial: Study protocol and coaching intervention, Jane M. Garbutt, Gabrielle Highstein, Yan Yan, and Robert C. Strunk

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Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways, Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, and Alison M. Goate

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Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner, Aparna Kaul, Yi-Hsien Chen, Ryan J. Emnett, Sonika Dahiya, and David H. Gutmann

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Peripheral-blood stem cells versus bone marrow from unrelated donors, Peter Westervelt and et al

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Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions, Keith F. Decker, Dali Zheng, Yuhong He, Tamara Bowman, John R. Edwards, and Li Jia

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Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104), Thomas F. Gajewski, April KS Salama, Donna Niedzwiecki, Jeffrey Johnson, Gerald Linette, Cynthia Bucher, Michelle A. Blaskovich, Said M. Sebti, Frank Haluska, and Cancer and Leukemia Group B

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Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1, Xiaolin Tu, Jianquan Chen, Joohyun Lim, Courtney M. Karner, Seung-Yon Lee, Julia Heisig, Cornelia Wiese, Kameswaran Surendran, Raphael Kopan, Manfred Gessler, and Fanxin Long

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Plasmodium falciparum  heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers, Vasant Muralidharan, Anna Oksman, Priya Pal, Susan Lindquist, and Daniel E. Goldberg

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Political and social determinants of life expectancy in less developed countries: A longitudinal study, Ro-Ting Lin, Ya-Mei Chen, Lung-Chang Chien, and Chang-Chuan Chan

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Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection, Wei-Jen Chua, Steven M. Truscott, Christopher S. Eickhoff, Azra Blazevic, Daniel F. Hoft, and Ted H. Hansen

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Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer’s disease Ibero-American cohort, Sheng C. Jin, Pau Pastor, Breanna Cooper, Sebastian Cervantes, Bruno A. Benitez, Cristina Razquin, Alison Goate, Ibero-American Alzheimer Disease Genetics Group Researchers, and Carlos Cruchaga

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Population-based rare variant detection via pooled exome or custom hybridization capture with or without individual indexing, Enrique Ramos, Benjamin T. Levinson, Sara Chasnoff, Andrew Hughes, Andrew L. Young, Katherine Thornton, Allie Li, Francesco L.M Vallania, Michael Province, and Todd E. Druley

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Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats, Ryan G. Toedebusch, Thomas E. Childs, Shari R. Hamilton, Jan R. Crowley, Frank W. Booth, and Michael D. Roberts

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Potential implications of HCN channel dysfunction after subarachnoid hemorrhage, Ananth K. Vellimana

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Prefrontal and striatal activity related to values of objects and locations, Soyoun Kim, Xinying Cai, Jaewon Hwang, and Daeyeol Lee

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Prevention of musculoskeletal disorders in workers: Classification and health surveillance – statements of the Scientific Committee on Musculoskeletal Disorders of the International Commission on Occupational Health, Mats Hagberg, Francesco Saverio Violante, Roberta Bonfiglioli, Alexis Descatha, Judith Gold, Brad Evanoff, and Judith K. Sluiter

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PrimerBank: A PCR primer database for quantitative gene expression analysis, 2012 update, Xiaowei Wang, Athanasia Spandidos, Huajun Wang, and Brian Seed

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Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system, Jamie M. Ireland and Emil R. Unanue

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Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease, Xu He, Thomas Haselhorst, Mark von Itzstein, Daniel Kolarich, Nicolle H. Packer, Tracey M. Gloster, David J. Vocadlo, Lorne A. Clarke, Yi Qian, and Allison R. Kermode

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Progression from sustained BK viruria to sustained BK viremia with immunosuppression reduction is not associated with changes in the noncoding control region of the BK virus genome, Imran A. Memon, Bijal A. Parikh, Monique Gaudreault-Keener, Rebecca Skelton, Gregory A. Storch, and Daniel C. Brennan

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Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma, Rachel L. Kyllo, Youssef S. Tanagho, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Shahab P. Hillyer, Shyam S. Sukumar, Kenneth G. Nepple, and Sam B. Bhayani

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Prospective trial of a pediatric ventricular assist device, Charles E. Canter and et al

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Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation, Shaw-Wei D. Tsen, Tzyy C. Wu, Juliann G. Kiang, and Kong-Thon Tsen

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Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception, Yingqi Weng, Patricia A. Batista-Schepman, Marie E. Barabas, Eli Q. Harris, Thomas B. Dinsmore, Elena A. Kossyreva, Audra M. Foshage, Michelle H. Wang, Matthew J. Schwab, Victoria M. Wang, Cheryl L. Stucky, and Gina M. Story

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Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a, Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, and Dong Yu

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Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease, Haoyan Chen, Genki Hayashi, Olivia Y. Lai, Alexander Dilthey, Peter J. Kuebler, Tami V. Wong, Maureen P. Martin, Marcelo A. Fernandez Vina, Gil McVean, Matthias Wabl, Kieron S. Leslie, Toby Maurer, Jeffrey N. Martin, Steven G. Deeks, Mary Carrington, Anne M. Bowcock, Douglas F. Nixon, and Wilson Liao

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Putative factors that may modulate the effect of exercise on liver fat: Insights from animal studies, Faidon Magkos

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PyXNAT: XNAT in Python, Yannick Schwartz, Alexis Barbot, Benjamin Thyreau, Vincent Frouin, Gael Varoquaux, Aditya Siram, Daniel S. Marcus, and Jean-Baptiste Poline

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Quantitative assessment of participant knowledge and evaluation of participant satisfaction in the CARES training program, Melody S. Goodman, Xuemei Si, Jewel D. Stafford, Adesuwa Obasohan, and Cheryl Mchunguzi

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Quantitative brain electrical activity in the initial screening of mild traumatic brain injuries, Brian O'Neil, Leslie S. Prichep, Roseanne Naunhemi, and Robert Chabot

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Quantitative trait loci affecting liver fat content in mice, Olga Minkina, James M. Cheverud, Gloria Fawcett, Clay F. Semenkovich, and Jane P. Kenney-Hunt