Open access journal articles published by WashU Medicine faculty in 2020 to the current year.

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Submissions from 2023

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Comparative genomics reveals the correlations of stress response genes and bacteriophages in developing antibiotic resistance of Staphylococcus saprophyticus, Kailun Zhang, Robert F Potter, Jamie Marino, Carol E Muenks, Matthew G Lammers, Jennifer Dien Bard, Tanis C Dingle, Romney Humphries, Lars F Westblade, Carey-Ann D Burnham, and Gautam Dantas

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Distinct gene expression signatures comparing latent tuberculosis infection with different routes of Bacillus Calmette-Guérin vaccination, Richard F Silver, Mei Xia, Chad E Storer, Jessica R Jarvela, Michelle C Moyer, Azra Blazevic, David A Stoeckel, Erin K Rakey, Jan M Tennant, Johannes B Goll, Richard D Head, and Daniel F Hoft

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DSM-5 conduct disorder and symptoms in youths at high risk of psychosis in Kenya with DSM-5 mental disorders and substance use: Towards integrated management, David M Ndetei, Victoria Mutiso, Christine Musyimi, Reinpeter Momanyi, Pascalyne Nyamai, Peter Tyrer, and Daniel Mamah

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Efficacy and safety of teprotumumab in patients with thyroid eye disease of long duration and low disease activity, Raymond S Douglas, Steven Couch, Sara T Wester, Brian T Fowler, Catherine Y Liu, Prem S Subramanian, Rosa Tang, Quang T Nguyen, Robi N Maamari, Shoaib Ugradar, Kate Hsu, Michael Karon, and Marius N Stan

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Pharmacokinetics of dacarbazine and unesbulin and CYP1A2-mediated drug interactions in patients with leiomyosarcoma, Lan Gao, Diksha Kaushik, Brian A Van Tine, Matthew A Ingham, Steven Attia, Christian F Meyer, Gary K Schwartz, Pius Maliakal, John D Baird, Jiyuan Ma, Rosemary Barrett, Dhiren D'Silva, Kylie O'Keefe, and Ronald Kong

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Instrumental variables for implementation science: Exploring context-dependent causal pathways between implementation strategies and evidence-based interventions, Aaloke Mody, Lindsey M Filiatreau, Charles W Goss, Byron J Powell, and Elvin H Geng

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The faculty-to-faculty mentorship experience: A survey on challenges and recommendations for improvements, Sarvenaz Sarabipour, Natalie M Niemi, Steven J Burgess, Christopher T Smith, Alexandre W Bisson Filho, Ahmed Ibrahim, and Kelly Clark

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A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection, Lucas J Adams, Laura A VanBlargan, Zhuoming Liu, Pavlo Gilchuk, Haiyan Zhao, Rita E Chen, Saravanan Raju, Zhenlu Chong, Bradley M Whitener, Swathi Shrihari, Prashant N Jethva, Michael L Gross, James E Crowe Jr., Sean P J Whelan, Michael S Diamond, and Daved H Fremont

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Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease, Peter R Millar, Brian A Gordon, Julie K Wisch, Tammie L.S. Benzinger, Carlos Cruchaga, Jason J Hassenstab, Laura Ibanez, Celeste Karch, Jorge J Llibre-Guerra, John C Morris, Richard J Perrin, Charlene Supnet-Bell, Chengjie Xiong, Randall J Bateman, Beau M Ances, Eric M McDade, and et al.

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Autophagy gene-dependent intracellular immunity triggered by interferon-γ, Michael R McAllaster, Jaya Bhushan, Dale R Balce, Anthony Orvedahl, Arnold Park, Seungmin Hwang, Meagan E Sullender, L David Sibley, and Herbert W Virgin

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Engineering E. coli strains using antibiotic-resistance-gene-free plasmids, Matthew B Amrofell, Sunaina Rengarajan, Steven T Vo, Erick S Ramirez Tovar, Larissa LoBello, Gautam Dantas, and Tae Seok Moon

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VODKA2: A fast and accurate method to detect non-standard viral genomes from large RNA-seq data sets, Emna Achouri, Sébastien A Felt, Matthew Hackbart, Nicole S Rivera-Espinal, and Carolina B López

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Integrative analysis of clinicopathological features defines novel prognostic models for mantle cell lymphoma in the immunochemotherapy era: A report from The North American Mantle Cell Lymphoma Consortium, Julie M Vose, Brad S Kahl, and et al.

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A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs, Debajit Dey, Enya Qing, Yanan He, Yihong Chen, Benjamin Jennings, Whitaker Cohn, Suruchi Singh, Lokesh Gakhar, Nicholas J Schnicker, Brian G Pierce, Julian P Whitelegge, Balraj Doray, John Orban, Tom Gallagher, and S Saif Hasan

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Cell-free RNA signatures predict Alzheimer's disease, Alejandro Cisterna-García, Aleksandra Beric, Muhammad Ali, Jose Adrian Pardo, Hsiang-Han Chen, Maria Victoria Fernandez, Joanne Norton, Jen Gentsch, Kristy Bergmann, John Budde, Joel S Perlmutter, John C Morris, Carlos Cruchaga, Juan A Botia, and Laura Ibanez

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Combining the tyrosine kinase inhibitor cabozantinib and the mTORC1/2 inhibitor sapanisertib blocks ERK pathway activity and suppresses tumor growth in renal cell carcinoma, Yige Wu, Siqi Chen, Xiaolu Yang, Kazuhito Sato, Preet Lal, Andrew T Shinkle, Michael C Wendl, Tina M Primeau, Yanyan Zhao, Alanna Gould, Hua Sun, Jacqueline L Mudd, Jeremy Hoog, R Jay Mashl, Matthew A Wyczalkowski, Chia-Kuei Mo, Ruiyang Liu, John M Herndon, Sherri R Davies, Di Liu, Xi Ding, Ramaswamy Govindan, Shunqiang Li, James Hsieh, Ryan C Fields, Kian-Huat Lim, Cynthia X Ma, Li Ding, Feng Chen, and et al.

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Diversity and dissemination of viruses in pathogenic protozoa, Senne Heeren, Ilse Maes, Mandy Sanders, Lon-Fye Lye, Vanessa Adaui, Jorge Arevalo, Alejandro Llanos-Cuentas, Lineth Garcia, Philippe Lemey, Stephen M Beverley, James A Cotton, Jean-Claude Dujardin, and Frederik Van den Broeck

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Host-microbiome interactions in distinct subsets of preterm labor and birth, Jose Galaz, Roberto Romero, Jonathan M Greenberg, Kevin R Theis, Marcia Arenas-Hernandez, Yi Xu, Marcelo Farias-Jofre, Derek Miller, Tomi Kanninen, Valeria Garcia-Flores, and Nardhy Gomez-Lopez

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T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease, Farzaneh Rahmani, Matthew R Brier, Brian A Gordon, Nicole McKay, Shaney Flores, Sarah Keefe, Russ Hornbeck, Beau Ances, Nelly Joseph-Mathurin, Chengjie Xiong, Guoqiao Wang, Cyrus A Raji, Jorge J Libre-Guerra, Richard J Perrin, Eric McDade, Alisha Daniels, Celeste Karch, John C Morris, Randall J Bateman, Tammie L S Benzinger, and et al.

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APOBEC-1 deletion enhances cisplatin-induced acute kidney injury, Xiaojia Guo, Valerie Blanc, Nicholas O Davidson, Heino Velazquez, Tian-Min Chen, Dennis G Moledina, Gilbert W Moeckel, Robert L Safirstein, and Gary V Desir

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Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma, Julien Calderaro, Pooja Navale, and et al.

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Designing for dissemination among public health and clinical practitioners in the USA, Thembekile Shato, Maura M Kepper, Gabriella M McLoughlin, Rachel G Tabak, Russell E Glasgow, and Ross C Brownson

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Does patella lowering as part of multilevel surgery improve knee kinematics in children with cerebral palsy and crouch gait? A meta-analysis of comparative studies, María Galán-Olleros, Sergio Lerma-Lara, Beltran Torres-Izquierdo, Ana Ramírez-Barragán, Rosa M Egea-Gámez, Pooya Hosseinzadeh, and Ignacio Martínez-Caballero

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What do infectious disease specialists think about managing long COVID?, Maureen D Lyons, Susan E Beekmann, Philip M Polgreen, and Jonas Marschall

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A multicenter evaluation of pediatric emergency department injury visits during the COVID-19 pandemic, Holly R Hanson, Puja Desai, Lindsay D Clukies, and et al.

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Modbed track: Visualization of modified bases in single-molecule sequencing, Daofeng Li, Xiaoyu Zhuo, Jessica K Harrison, Shane Liu, and Ting Wang

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The accuracy of flap thickness and diameter in LASIK using a femtosecond laser, Stephen A Wexler and Brad Hall

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A multilevel mHealth intervention boosts adherence to hydroxyurea in individuals with sickle cell disease, Jane S Hankins, Allison A King, Ana A Baumann, Lisa M Klesges, and et al.

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A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization, Brett Volmert, Chao Zhou, and et al.

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Overall survival of patients with cHL who progress after autologous stem cell transplant: Results in the novel agent era, Sanjal H Desai, Brad Kahl, Raya Saba, and et al.

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Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+GZMB−CD8+ memory T cells and accumulation of type 2 memory T cells, Marina Terekhova, Amanda Swain, Pavla Bohacova, Ekaterina Aladyeva, Laura Arthur, Anwesha Laha, Denis A Mogilenko, Samantha Burdess, Vladimir Sukhov, Denis Kleverov, Barbora Echalar, Petr Tsurinov, Roman Chernyatchik, Kamila Husarcikova, and Maxim N Artyomov

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Antibody binding captures high energy state of an antigen: The case of Nsp1 SARS-CoV-2 as revealed by hydrogen-deuterium exchange mass spectrometry, Ravi Kant, Nawneet Mishra, and Michael L Gross

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Applications of implementation science frameworks, models and theories in disparities-focused cancer screening interventions: A scoping review protocol, Serena Xiong, Lisa Klesges, Michelle Doering, and Rebekah J Pratt

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Reproductive decision making in women with medical comorbidities: A qualitative study, Elena M Kraus, Niraj R Chavan, Victoria Whelan, Jennifer Goldkamp, and James M DuBois

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A Drosophila heart optical coherence microscopy dataset for automatic video segmentation, Matthew Fishman, Abigail Matt, Fei Wang, Elena Gracheva, Jiantao Zhu, Xiangping Ouyang, Andrey Komarov, Yuxuan Wang, Hongwu Liang, and Chao Zhou

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Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications, Mingxing Qian, Yuanjian Xu, and Douglas F Covey

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Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein, Ryan B. Day, Julia A. Hickman, Ziheng Xu, Casey Ds Katerndahl, Francesca Ferraro, Sai Makund Ramakrishnan, Petra Erdmann-Gilmore, Robert W. Sprung, Yiling Mi, R. Reid Townsend, Christopher A. Miller, and Timothy J. Ley

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Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor, Edin Muratspahić, Jianming Han, Balazs R Varga, Kevin Appourchaux, Susruta Majumdar, Tao Che, and et al.

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Docking for EP4R antagonists active against inflammatory pain, Stefan Gahbauer, Tao Che, and et al.

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Preconception counseling in a patient with a mechanical aortic valve and recent ischemic stroke, Kristen E Wong, Alan C Braverman, Tsuyoshi Kaneko, Alan Zajarias, and Amanda K Verma

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DNA methylation-mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation, Ding Xiao, Liang Fang, Zhongting Liu, Yonghua He, Jun Ying, Haocheng Qin, Aiwu Lu, Meng Shi, Tiandao Li, Bo Zhang, Jianjun Guan, Cuicui Wang, Yousef Abu-Amer, and Jie Shen

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From mother to infant, from placenta to gut: Understanding varied microbiome profiles in neonates, Riadh Cheddadi, Venkata Yeramilli, and Colin Martin

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Role of sex in the association of socioeconomic status with cardiovascular health in Black Americans: The Jackson Heart Study, Joshua J Joseph, Amaris Williams, Rosevine A Azap, Songzhu Zhao, Guy Brock, David Kline, James B Odei, Randi Foraker, Mario Sims, LaPrincess C Brewer, Darrell M Gray II, and Timiya S Nolan

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Trends in ductus arteriosus stent versus Blalock-Taussig-Thomas shunt use and comparison of cost, length of stay, and short-term outcomes in neonates with ductal-dependent pulmonary blood flow: An observational study using the Pediatric Health Information Systems database, Bethan A Lemley, Lezhou Wu, Amy L Roberts, Russell T Shinohara, William O Quarshie, Athar M Qureshi, Christopher L Smith, Yoav Dori, Matthew J Gillespie, Jonathan J Rome, Andrew C Glatz, Sandra Amaral, and Michael L O'Byrne

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Maternal diet during early gestation influences postnatal taste activity-dependent pruning by microglia, Chengsan Sun, Shuqiu Zheng, Justin S A Perry, Geoffrey T Norris, Mei Cheng, Fanzhen Kong, Rolf Skyberg, Jianhua Cang, Alev Erisir, Jonathan Kipnis, and David L Hill

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Older adults' and caregivers' perceptions about urinary tract infection and asymptomatic bacteriuria guidelines: A qualitative exploration, Michael J Durkin, Viktoria Schmitz, Kevin Hsueh, Zoe Troubh, and Mary C Politi

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Prevalence, characteristics, and correlates of probable avoidant/restrictive food intake disorder among adult respondents to the National Eating Disorders Association online screen: A cross-sectional study, Laura D'Adamo, Lauren Smolar, Katherine N Balantekin, C Barr Taylor, Denise E Wilfley, and Ellen E Fitzsimmons-Craft

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Transient receptor potential vanilloid 4-dependent microglial function in myelin injury and repair, Jameson P Holloman, Sophia H Dimas, Angela S Archambault, Fabia Filipello, Lixia Du, Jing Feng, Yonghui Zhao, Bryan Bollman, Laura Piccio, Andrew J Steelman, Hongzhen Hu, and Gregory F Wu

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Predicting cognitive dysfunction and regional hubs using Braak staging amyloid-beta biomarkers and machine learning, Puskar Bhattarai, Ahmed Taha, Bhavin Soni, Deepa S Thakuri, Erin Ritter, and Ganesh B Chand

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Adverse events and complications after primary ACL reconstruction with quadriceps tendon autograft: A systematic review, Garrett R Jackson, Enzo S Mameri, Trevor Tuthill, Morgan Wessels, Shaan Asif, Joan Sugrañes, Anjay K Batra, Johnathon R McCormick, Obianuju A Obioha, Daniel J Kaplan, Derrick M Knapik, Nikhil N Verma, and Jorge Chahla

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A multisociety Delphi consensus statement on new fatty liver disease nomenclature, Mary E. Rinella, Samuel Klein, and et al.

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An "off-the-shelf" CD2 universal CAR-T therapy for T-cell malignancies, Jingyu Xiang, Jessica M Devenport, Alun J Carter, Karl W Staser, Miriam Y Kim, Julie O' Neal, Julie K Ritchey, Michael P Rettig, Feng Gao, Garrett Rettig, Rolf Turk, Byung Ha Lee, Matthew L Cooper, and John F DiPersio

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APOE genotype and Alzheimer disease risk across age, sex, and population ancestry, Michael E Belloy, Shea J Andrews, Yann Le Guen, Michael Cuccaro, Lindsay A Farrer, Valerio Napolioni, and Michael D Greicius

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A qualitative exploration of sakeholders' preferences for early-stage rectal cancer treatment, Merrill E. Rubens, Timothy P. Mayo, Radhika K. Smith, Sean C. Glasgow, and Mary C. Politi

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Associations of awake prone positioning-induced changes in physiology with intubation: An international prospective observational study in patients with acute hypoxemic respiratory failure related to COVID-19, Luis Morales-Quinteros, Raffaele Scala, João Manoel Silva, Antonio Leidi, Alexandre Leszek, Rodrigo Vazquez-Guillamet, Sergi Pascual, Ary Serpa-Neto, Antonio Artigas, and Marcus J Schultz

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Beyond the single-outcome approach: A comparison of outcome-wide analysis methods for exposome research, Augusto Anguita-Ruiz, Chongliang Luo, and et al.

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Bintrafusp alfa versus pembrolizumab in patients with treatment-naive, programmed death-ligand 1-high advanced NSCLC: A randomized, open-label, phase 3 trial, Byoung Chul Cho, Clifford Robinson, and et al.

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Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes, Marcelo Farias-Jofre, Valeria Garcia-Flores, Nardhy Gomez-Lopez, and et al.

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Conserved and divergent gene regulatory programs of the mammalian neocortex, Nathan R Zemke, Daofeng Li, Xiaoyu Zhuo, Vincent Xu, Ting Wang, and et al.

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Continuous subcutaneous foslevodopa/foscarbidopa in Parkinson's disease: Safety and efficacy results from a 12-month, single-arm, open-label, phase 3 study, Jason Aldred, Susan R Criswell, and et al.

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Core warming of coronavirus disease 2019 patients undergoing mechanical ventilation: A pilot study, Nathaniel P Bonfanti, Nicholas M Mohr, David C Willms, Roger J Bedimo, Emily Gundert, Kristina L Goff, Erik B Kulstad, and Anne M Drewry

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Correlating deep learning-based automated reference kidney histomorphometry with patient demographics and creatinine, Nicholas Lucarelli, Brandon Ginley, Jarcy Zee, Sayat Mimar, Anindya S. Paul, Sanjay Jain, Seung Seok Han, Luis Rodrigues, Tezcan Ozrazgat-Baslanti, Michelle L. Wong, Girish Nadkarni, William L. Clapp, Kuang-Yu Jen, and Pinaki Sarder

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Delayed-enhancement cardiac magnetic resonance imaging detects disease progression in patients with mitral valve disease and atrial fibrillation, Tari-Ann Yates, Ramya Vijayakumar, Martha McGilvray, Ali J Khiabani, Nicholas Razo, Laurie Sinn, Matthew R Schill, Nassir Marrouche, Christian Zemlin, and Ralph J Damiano Jr

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Denoising task-related fMRI: Balancing noise reduction against signal loss, M E Hoeppli, M A Garenfeld, C K Mortensen, H Nahman-Averbuch, C D King, and R C Coghill

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Diroximel fumarate in patients with relapsing-remitting multiple sclerosis: Final safety and efficacy results from the phase 3 EVOLVE-MS-1 study, Barry A Singer, Robert T Naismith, and et al.

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Droplet digital PCR for oncogenic KMT2A fusion detection, Andrew L Young, Hannah C Davis, and Grant A Challen

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Endoscopic management of tracheoesophageal prosthesis-induced esophageal mucosal bridge, Mahmoud Y. Madi, Matthew Peller, Michael Presti, and Ahmad Najdat Bazarbashi

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Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis, Danielle N. Alfano, Mark J. Miller, and Juliane Bubeck-Wardenburg

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Enlarged perivascular spaces in infancy and autism diagnosis, cerebrospinal fluid volume, and later sleep problems, Dea Garic, Robert C McKinstry, Kelly N Botteron, and et al.

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Firearm injury among people experiencing homelessness: Cross-sectional evidence from a national survey of United States emergency departments, Nathaniel A Dell, Michael G Vaughn, and Christopher P Salas-Wright

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Greater socioenvironmental risk factors and higher chronic pain stage are associated with thinner bilateral temporal lobes, Lisa H Antoine, Burel R Goodin, and et al.

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Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development, Devesha H Kulkarni, Brigida Rusconi, Alexandria N Floyd, Elisabeth L Joyce, Khushi B Talati, Hrishi Kousik, Dereck Alleyne, Dalia L Harris, Lorena Garnica, Ryan McDonough, Shay S Bidani, Hrishikesh S Kulkarni, Elizabeth P Newberry, Keely G McDonald, and Rodney D Newberry

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High-risk human papillomavirus-associated corneal/conjunctival intraepithelial neoplasia in a young patient, Jessica Y Walia, George J Harocopos, and Augustine R Hong

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Idasanutlin and navitoclax induce synergistic apoptotic cell death in T-cell acute lymphoblastic leukemia, Kimberly B Johansson, Megan S Zimmerman, Iryna V Dmytrenko, Feng Gao, and Daniel C Link

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Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: Synthesis, biological evaluations and modelling insights, Waleed A Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M Abd-Alhaseeb, Sara T Al-Rashood, Giri Babu Veerakanellore, Taghreed A Majrashi, Eslam B Elkaeed, Bahaa Elgendy, Paola Gratteri, Claudiu T Supuran, Wagdy M Eldehna, and Mohamed Elagawany

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Incidence of rapidly progressive osteoarthritis following intra-articular hip corticosteroid injection: A systematic review and meta-analysis, Franco M. Sabatini, Anna Cohen-Rosenblum, Travis B. Eason, Charles P. Hannon, Samuel D. Mounce, Chad A. Krueger, F Winston Gwathmey, Stephen T. Duncan, and David C. Landy

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Increasing energetic demands on photoreceptors in diabetes corrects retinal lipid dysmetabolism and reduces subsequent microvascular damage, Sheng Zhang, Xiaochao Wei, Megan Bowers, Sebastian Jessberger, Marcin Golczak, Clay F Semenkovich, and Rithwick Rajagopal

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Intrinsically disordered regions are poised to act as sensors of cellular chemistry, David Moses, Garrett M Ginell, Alex S Holehouse, and Shahar Sukenik

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KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster, Meghna Singh, Sarah J Spendlove, Angela Wei, Leroy M Bondhus, Aileen A Nava, Francisca N de L Vitorino, Seth Amano, Jacob Lee, Gesenia Echeverria, Dianne Gomez, Benjamin A Garcia, and Valerie A Arboleda

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Lasofoxifene versus fulvestrant for ER+/HER2- metastatic breast cancer with an ESR1 mutation: Results from the randomized, phase II ELAINE 1 trial, M P Goetz, N A Bagegni, and et al.

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Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families, Brian A Kleiboeker, Cheryl Frankfater, Mary E Davey, and Fong-Fu Hsu

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Local treatment and treatment-related adverse effects among patients with advanced prostate cancer, Saira Khan, Su-Hsin Chang, Mei Wang, Eric H Kim, Martin W Schoen, Carleena Rocuskie-Marker, and Bettina F Drake

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Longitudinal lipidomic profiles during pregnancy and associations with neonatal anthropometry: Findings from a multiracial cohort, Yiqing Song, Ruijin Lu, Guoqi Yu, Mohammad L Rahman, Liwei Chen, Yeiyi Zhu, Michael Y Tsai, Oliver Fiehn, Zhen Chen, and Cuilin Zhang

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Low grade endometrial stromal sarcoma in pregnancy: A case in support of safe abortion access, Rachel L. Furuya, David L. Eisenberg, Diana L. Gray, Vincent M. Mellnick, and Premal H. Thaker

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Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications, Daniel F Levey, Emma C Johnson, Arpana Agrawal, and et al.

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Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals, Hang Zhou, Emma C Johnson, Pamela A F Madden, Andrew C Heath, Arpana Agrawal, and et al.

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Myeloid lineage switch following CD7-targeted chimeric antigen receptor T-cell therapy in relapsed/refractory T-cell acute lymphoblastic leukemia, Ibrahim Aldoss, David Spencer, and et al.

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Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia, Leonard D Kuhrt, Edyta Motta, Nirmeen Elmadany, Hannah Weidling, Raphaela Fritsche-Guenther, Ibrahim E Efe, Olivia Cobb, Jit Chatterjee, Lucy G Boggs, Marina Schnauß, Sebastian Diecke, Marcus Semtner, Corina Anastasaki, David H Gutmann, and Helmut Kettenmann

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Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium, Xi Zhu, Evan M Gordon, and et al.

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Normalization of drug and therapeutic concepts with Thera-Py, Matthew Cannon, James Stevenson, Kori Kuzma, Susanna Kiwala, Jeremy L Warner, Obi L Griffith, Malachi Griffith, and Alex H Wagner

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Obesity and outcomes of Kawasaki disease and COVID-19-related multisystem inflammatory syndrome in children, Michael Khoury, William B Orr, and et al.

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Optimized strategy for real-time qPCR detection of Onchocerca volvulus DNA in pooled Simulium sp. blackfly vectors, Mary Doherty, Peter U. Fischer, and et al.

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Organ aging signatures in the plasma proteome track health and disease, Hamilton Se-Hwee Oh, Yun Ju Sung, Lihua Wang, Jigyasha Timsina, Dan Western, Menghan Liu, Pat Kohlfeld, John Budde, Carlos Cruchaga, and et al.

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Patient and hospital characteristics associated with the interhospital transfer of adult patients with sepsis, Uchenna R. Ofoma, Tierney J. Lanter, Elena Deych, Marin Kollef, Fei Wan, and Karen E. Joynt Maddox

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Pelvic index: A new pelvic parameter for assessing sagittal spinal alignment, Justice U Achonu, Kenny Ling, Rohit Bhan, Alexander Garcia, David E Komatsu, and Nicholas A Pallotta

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Phase 1/1b open-label, dose-escalation study of fruquintinib in patients with advanced solid tumors in the United States, Andrea Wang-Gillam, William Schelman, Stacey Ukrainskyj, Caly Chien, Martha Gonzalez, Zhao Yang, Marek Kania, and Heather Yeckes-Rodin

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Primary bulbar conjunctival basal cell carcinoma: A clinical-pathologic report and literature review, Rebecca Z Lin, Augustine R Hong, and George J Harocopos

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Primary results of the SAVAL randomized trial of a paclitaxel-eluting nitinol stent versus percutaneous transluminal angioplasty in infrapopliteal arteries, Hans van Overhagen, Patrick J Geraghty, and et al.

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Programmable and reversible integrin-mediated cell adhesion reveals hysteresis in actin kinetics that alters subsequent mechanotransduction, Zheng Zhang, Guy M Genin, and et al.

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Progressive, edematous plaques, mild pancytopenia, and inflammation, Leigh A Compton, Heather A Jones, Connor A Vinyard, Yi-Shan Lee, Matthew J Walter, and Christine C Yokoyama