Open access journal articles published by WashU Medicine faculty in 2020 to the current year.
Submissions from 2024
Parenting practices and interventions during the COVID-19 pandemic lockdown: An exploratory cross-sectional study of caregivers in Brazil, Mexico, and the United States, Mariana M Juras, Acileide Cristiane F Coelho, Alejandro L Vázquez, Michela Ribeiro, Marina Kohlsdorf, Alice Lima Custódio, Nancy G Amador Buenabad, Lucia Vazquez Perez, Cole Hooley, Miya L Barnett, and Ana A Baumann
A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis, Javan K Kisaka, Daniel Rauch, Malachi Griffith, and George B Kyei
Blocking senescence and tolerogenic function of dendritic cells induced by γδ Treg cells enhances tumor-specific immunity for cancer immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, and Guangyong Peng
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly, Francis Shue, Rachel Hendrix, Jason Ulrich, Rachel L Henson, William Knight, Chengjie Xiong, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M Holtzman, and et al.
Subcellular pathways through VGluT3-expressing mouse amacrine cells provide locally tuned object-motion-selective signals in the retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam McCoy, Katia Valkova, Daniel Kerschensteiner, and Josh L Morgan
Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells, Kyle A Cottrell, Sua Ryu, Jackson R Pierce, Luisangely Soto Torres, Holly E Bohlin, Angela M Schab, and Jason D Weber
Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution, Rahul Tyagi, Bruce A Rosa, Amanda Swain, Maxim N Artyomov, Douglas P Jasmer, and Makedonka Mitreva
Type 1 VWD classification revisited: Novel insights from combined analysis of the LoVIC and WiN studies, Ferdows Atiq, Jorge Di Paola, and et al.
VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response, Thomas Thisted, Yoshiko Takeuchi, Robert D Schreiber, and et al.
Perioperative mental health intervention for depression and anxiety symptoms in older adults study protocol: Design and methods for three linked randomised controlled trials, Katherine J Holzer, Kimberly A Bartosiak, Ryan P Calfee, Chet W Hammill, Simon Haroutounian, Benjamin D Kozower, Theresa A Cordner, Emily M Lenard, Kenneth E Freedland, Bethany R Tellor Pennington, J Philip Miller, Mary C Politi, Yi Zhang, Michael D Yingling, Ana A Baumann, Thomas Kannampallil, Julia A Schweiger, Sherry L McKinnon, Michael S Avidan, Eric J Lenze, Joanna Abraham, and et al.
A compendium of multi-omics data illuminating host responses to lethal human virus infections, Amie J Eisfeld, Larissa B Thackray, Qing Tan, Michael S Diamond, and et al.
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity, Max C Petersen, Gordon I Smith, Hector H Palacios, Sarah S Farabi, Mihoko Yoshino, Jun Yoshino, Kevin Cho, Victor G Davila-Roman, Ruteja A Barve, Jinsheng Yu, Jennifer H Stern, Bruce W Patterson, Gary J Patti, Samuel Klein, and et al.
Environmental and sociocultural factors are associated with pain-related brain structure among diverse individuals with chronic musculoskeletal pain: Intersectional considerations, Lisa H Domenico, Jared J Tanner, Angela M Mickle, Ellen L Terry, Cynthia Garvan, Song Lai, Hrishikesh Deshpande, Roland Staud, David Redden, Catherine C Price, Burel R Goodin, Roger B Fillingim, and Kimberly T Sibille
Health factors associated with development and severity of poststroke dysphagia: An epidemiological investigation, Brittany N Krekeler, Opeolu Adeoye, and et al.
NFĸB signaling drives myocardial injury via CCR2+ macrophages in a preclinical model of arrhythmogenic cardiomyopathy, Stephen P. Chelko, Vinay R. Penna, Morgan Engel, Emily A. Shiel, Ann M. Centner, Waleed Farra, Elisa N. Cannon, Maicon Landim-Vieira, Niccole Schaible, Kory Lavine, and Jeffrey E. Saffitz
Abatacept pharmacokinetics and exposure response in patients hospitalized with COVID-19: A secondary analysis of the ACTIV-1 IM randomized clinical trial, Stephen J Balevic, Daniel K Benjamin, William G Powderly, P Brian Smith, Daniel Gonzalez, Matthew W McCarthy, Linda K Shaw, Christopher J Lindsell, Sam Bozzette, Daphne Williams, Benjamin P Linas, John Blamoun, Heta Javeri, Christoph P Hornik, and ACTIV-1 IM Study Group
Adipose tissue peroxisomal lipid synthesis orchestrates obesity and insulin resistance through LXR-dependent lipogenesis, Brian Kleiboeker, Anyuan He, Min Tan, Dongliang Lu, Donghua Hu, Xuejing Liu, Parniyan Goodarzi, Fong-Fu Hsu, Babak Razani, Clay F Semenkovich, and Irfan J Lodhi
Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods, Alejandro Omar Blenkmann, Sabine Liliana Leske, Anaïs Llorens, Jack J Lin, Edward F Chang, Peter Brunner, Gerwin Schalk, Jugoslav Ivanovic, Pål Gunnar Larsson, Robert Thomas Knight, Tor Endestad, and Anne-Kristin Solbakk
A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y, Suhas Bobba, Kuldeep S. Chauhan, Sadia Akter, Shibali Das, Ekansh Mittal, Barun Mathema, Jennifer A. Philips, and Shabaana A. Khader
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling, Baohai Shao, Masami Shimizu-Albergine, Farah Kramer, Jenny E Kanter, Jay W Heinecke, Tomas Vaisar, Bettina Mittendorfer, Bruce W Patterson, and Karin E Bornfeldt
Automated model building and protein identification in cryo-EM maps, Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, and Sjors H W Scheres
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease, Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, and Oscar Harari
Cannabis oil extracts for chronic pain: What else can be learned from another structured prospective cohort?, Dorit Pud, Suhail Aamar, Bareket Schiff-Keren, Roee Sheinfeld, Silviu Brill, Dror Robinson, Yaakov Fogelman, George Habib, Haggai Sharon, Howard Amital, Boris Boltyansky, Simon Haroutounian, and Elon Eisenberg
Changing perceptions about the dermatology residency application process among applicants and program directors: 2020-2022, Fatuma-Ayaan B. Rinderknecht, Kandice C. Bailey, Danielle E. Novack, Adena E. Rosenblatt, Dana Dunleavy, Bobby D. Naemi, Ilana S. Rosman, Ammar Ahmed, and Scott Worswick
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy, Danira Toral-Rios, Justin M Long, Jason D Ulrich, Jinsheng Yu, Michael R Strickland, Xianlin Han, David M Holtzman, Anil G Cashikar, and Steven M Paul
Cognitive flexibility training for chronic pain: A randomized clinical study, Katherine J. Holzer, Marko S. Todorovic, Elizabeth A. Wilson, Aaron Steinberg, Michael S. Avidan, and Simon Haroutounian
Cognitive outcomes of children with sagittal craniosynostosis treated with either endoscopic or open calvarial vault surgery, Suresh N Magge, Annahita R Fotouhi, Virginia Allhusen, Brent R Collett, Gary B Skolnick, Sybill D Naidoo, Matthew D Smyth, Robert F Keating, Raj Vyas, Gary F Rogers, and Kamlesh B Patel
Degenerative meniscus tears treated nonoperatively with platelet-rich plasma yield variable clinical and imaging outcomes: A systematic review, Varun Gopinatth, Anjay K Batra, Jorge Chahla, Matthew V Smith, Matthew J Matava, Robert H Brophy, and Derrick M Knapik
DNA combing versus DNA spreading and the separation of sister chromatids, Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, and Alessandro Vindigni
Drug-induced liver injury in the elderly: Consensus statements and recommendations from the IQ-DILI Initiative, Eric B Cohen, Meenal Patwardhan, Ritu Raheja, David H Alpers, Raul J Andrade, Mark I Avigan, James H Lewis, Don C Rockey, Francis Chui, Alexandru M Iacob, Camila C Linardi, Arie Regev, Jesse Shick, and M Isabel Lucena
Early treatment with fluvoxamine, bromhexine, cyproheptadine, and niclosamide to prevent clinical deterioration in patients with symptomatic COVID-19: A randomized clinical trial, Dhammika Leshan Wannigama, Angela M Reiersen, and et al.
Endoscopic management of recurrent Zenker diverticula after failed surgical repairs, Sanjay Palat, Harsh Singh, Mahmoud Y Madi, and Ahmad Najdat Bazarbashi
Enhancing impact: A call to action for equitable Implementation Science, Rachel C Shelton and Ross C Brownson
Epigenetic underpinnings of tumor-immune dynamics in prostate cancer immune suppression, Duminduni Hewa Angappulige, Nupam P Mahajan, and Kiran Mahajan
Exploring the association between weight loss-inducing medications and multiple sclerosis: Insights from the FDA adverse event reporting system database, Afsaneh Shirani, Anne H Cross, and Olaf Stuve
Feasibility of surface-guidance combined with CBCT for intra-fractional breath-hold motion management during Ethos RT, Taeho Kim, Eric Laugeman, Kendall Kiser, Joshua Schiff, Shanti Marasini, Alex Price, H Michael Gach, Nels Knutson, Pamela Samson, Clifford Robinson, Casey Hatscher, and Lauren Henke
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests, Nicolas R Barthélemy, Suzanne E Schindler, Yingxin He, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Tammie L S Benzinger, John C Morris, Randall J Bateman, and et al.
HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells, Christopher Butler, Morgan Dunmire, Jaebok Choi, Gabor Szalai, Anissa Johnson, Wei Lei, Xin Chen, Liang Liu, Wei Li, Matthew J Walter, and Tuoen Liu
Incidence and mortality of COVID-19-associated invasive fungal infections among critically ill intubated patients: A multicenter retrospective cohort analysis, Julio C Zuniga-Moya, Benjamin Papadopoulos, Armaghan-E-Rehman Mansoor, Patrick B Mazi, Adriana M Rauseo, and Andrej Spec
Interstate highway connections and traced gun transfers between the 48 contiguous United States, Leah Roberts, Mark H Hoofnagle, Brady Bushover, Ariana N Gobaud, Christina A Mehranbod, Carolyn Fish, and Christopher N Morrison
Loncastuximab tesirine in relapsed/refractory diffuse large B-cell lymphoma: Long-term efficacy and safety from the phase II LOTIS-2 study, Paolo F. Caimi, Brad S Kahl, and et al.
Medicaid eligibility loss among dual-eligible beneficiaries before and during COVID-19 public health emergency, Yanlei Ma, Eric T Roberts, Kenton J Johnston, E John Orav, and Jose F Figueroa
MYSM1 attenuates DNA damage signals triggered by physiologic and genotoxic DNA breaks, Brendan Mathias, David O'Leary, Nermina Saucier, Faiz Ahmad, Lynn S White, Le'Mark Russell, Marwan Shinawi, Matthew J Smith, Roshini S Abraham, Megan A Cooper, Maleewan Kitcharoensakkul, Abby M Green, and Jeffrey J Bednarski
Neighborhood disadvantage and breast cancer-specific survival in the US, Neha Goel, Alexandra E Hernandez, and Angela Mazul
Neurosteroids and their potential as a safer class of general anesthetics, Hiroki Tateiwa and Alex S Evers
Neutrophils are indispensable for adverse cardiac remodeling in heart failure, Sergey Antipenko, Nicolas Mayfield, Miki Jinno, Matthias Gunzer, Mohamed Ameen Ismahil, Tariq Hamid, Sumanth D Prabhu, and Gregg Rokosh
Novel SGCE mutation in a patient with myoclonus-dystonia: A case report, Eva Klinman, Catherine Gooch, Joel S. Perlmutter, Albert A. Davis, and Baijayanta Maiti
Practical considerations for delandistrogene moxeparvovec gene therapy in patients with Duchenne muscular dystrophy, Jerry R Mendell, Crystal Proud, Craig M Zaidman, Stefanie Mason, Eddie Darton, Shufang Wang, Christoph Wandel, Alexander P Murphy, Eugenio Mercuri, Francesco Muntoni, and Craig M McDonald
Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition, Hao-Wei Chang, Evan M Lee, Yi Wang, Cyrus Zhou, Kali M Pruss, Suzanne Henrissat, Robert Y Chen, Clara Kao, Matthew C Hibberd, Hannah M Lynn, Daniel M Webber, Marie Crane, Jiye Cheng, Ye Chen, Jeffrey I Gordon, and et al.
Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin B6 metabolism, Michael P Whyte, Fan Zhang, Karen E Mack, Deborah Wenkert, Gary S Gottesman, Karen L Ericson, Jeffrey T Cole, and Stephen P Coburn
Quality assurance for focused ultrasound-induced blood-brain barrier opening procedure using passive acoustic detection, Chih-Yen Chien, Lu Xu, Jinyun Yuan, Siaka Fadera, Andrew H Stark, Umeshkumar Athiraman, Eric C Leuthardt, and Hong Chen
Reliability and validity of smartphone cognitive testing for frontotemporal lobar degeneration, Adam M Staffaroni, Nupur Ghoshal, Jason Hassenstab, and et al.
Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study, James W Wheless, Robert Edward Hogan, Charles S Davis, Enrique Carrazana, and Adrian L Rabinowicz
Sensitive MRD detection from lymphatic fluid after surgery in HPV-associated oropharyngeal cancer, Noah Earland, Nicholas P Semenkovich, Ricardo J Ramirez, Peter K Harris, Andrew I Hearn, Matthew Inkman, Jeffrey J Szymanski, Benjamin M Wahle, Kevin Chen, Irfan Alahi, Gabris Ni, Andrew Chen, Jin Zhang, Aadel A Chaudhuri, and et al.
Severity of respiratory syncytial virus vs COVID-19 and influenza among hospitalized US adults, Diya Surie, Jennie H Kwon, and et al.
T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) with negative screening immaturity markers and gamma-delta receptor expression, Maria Faraz, Anita Parmigiani, Nina Monkash, and Anne Chen
The DMPTool NIH DMSP templates project, Nina Exner, Seonyoung Kim, and Katy Smith
The impact of individual-level income predicted from the BRFSS on the association between insurance status and overall survival among adults with cancer from the SEER program, Justin M Barnes, Kimberly J Johnson, Nosayaba Osazuwa-Peters, and Matthew B Spraker
The performance of 11 fingertip pulse oximeters during hypoxemia in healthy human participants with varied, quantified skin pigment, Gregory Leeb, Leonid Shmuylovich, and et al.
Threat experiences moderate the link between hippocampus volume and depression symptoms prospectively in adolescence, Max P Herzberg, Meriah L DeJoseph, Joan Luby, and Deanna M Barch
Trapdoor endarterectomy for coral reef plaque of the paravisceral aorta in the modern era, Jackson S Burton, Nathan M Droz, Vipul Khetarpaul, Luis A Sanchez, and J Westley Ohman
Using the Consolidated Framework for Implementation Research (CFIR) to guide implementation of cardio-oncology services, Jessica Miller Clouser, Colleen A McMullen, Akosua K Adu, Gretchen Wells, Amit Arbune, and Jing Li
WHO's essential medicines and AWaRe: Recommendations on first- and second-choice antibiotics for empiric treatment of clinical infections, Lorenzo Moja, Sumanth Gandra, and et al.
2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation, Stylianos Tzeis, Ralph J Damiano, and et al.
ArCH: Improving the performance of clonal hematopoiesis variant calling and interpretation, Irenaeus C C Chan, Alex Panchot, Evelyn Schmidt, Brian J Wiley, Jie Liu, Kimberly Turner, Duc Tran, J Scott Beeler, Armel Landry Batchi-Bouyou, Daniel C Link, Kelly L Bolton, and et al.
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue, Dhruva D Dhavale, Katherine Basore, Isabelle R Gordon, Jialu Liu, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Brock Summers, Richard J Perrin, Joel S Perlmutter, James A J Fitzpatrick, Paul T Kotzbauer, and et al.
Comparative lipidome study of maternal plasma, milk, and lamb plasma in sheep, Soundara Viveka Thangaraj, Adel Ghnenis, Brooke Pallas, Arpita Kalla Vyas, Brigid Gregg, and Vasantha Padmanabhan
Using stated preference methods to facilitate knowledge translation in implementation science, Whitney C Irie, Andrew Kerkhoff, Hae-Young Kim, Elvin Geng, and Ingrid Eshun-Wilson
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI, Jonathan J Molina, Wei Xu, Karla Bergeron, Aleksandra Klim, Michael G Caparon, Scott J Hultgren, Alana Desai, and et al.
Efficacy and feasibility of short-stretch compression therapy for filarial lymphedema in Sri Lanka, Jaimee M Hall, Nirmitha Lalindi De Silva, Janaka Ruben, Sandani S Thilakarathne, Thishan Channa Yahathugoda, and Philip J Budge
Impact of imaging frequency on progression-free survival in Alliance trials enrolling patients with follicular lymphoma, Sarah C Rutherford, Jun Yin, Levi D Pederson, Kristie A Blum, Peter Martin, Sin-Ho Jung, Barbara Grant, Cara Rosenbaum, Bruce D Cheson, Nancy L Bartlett, Sumithra J Mandrekar, and John P Leonard
Intergenerational protective anti-gut commensal immunoglobulin G originates in early life, Brigida Rusconi, Adina K Bard, Ryan McDonough, Angel M Kindsvogel, Jacqueline D Wang, Sreeram Udayan, Keely G McDonald, Rodney D Newberry, and Phillip I Tarr
Ly6C+ monocytes in the skin promote systemic alphavirus dissemination, Autumn C Holmes, Cormac J Lucas, Morgan E Brisse, Brian C Ware, Heather D Hickman, Thomas E Morrison, and Michael S Diamond
Next generation microfluidics: Fulfilling the promise of lab-on-a-chip technologies, Umut A Gurkan, Jorge Di Paola, and et al.
Phase 2 study of add-on parsaclisib for patients with myelofibrosis and suboptimal response to ruxolitinib: Final results, Abdulraheem Yacoub, Stephen T Oh, and et al.
Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization, Daniel Cancilla, Michael P Rettig, Darja Karpova, Haresh Thakellapalli, Megh Singh, Marvin J Meyers, Peter G Ruminski, Stephanie Christ, Ezhilarasi Chendamarai, Feng Gao, Leah Gehrs, Julie K Ritchey, Michael Prinsen, and John F DiPersio
Distal extent of resection in type A dissection: Keeping it simple, Marc R Moon and Puja Kachroo
The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA, Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton, and Andrea Soranno
Application of learned ideal observers for estimating task-based performance bounds for computed imaging systems, Kaiyan Li, Umberto Villa, Hua Li, and Mark A. Anastasio
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer, Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Kiran Zahra, Vikas Somani, Iftikhar Ali Khawar, Hung-Po Chen, Paarth B Dodhiawala, Lin Li, Yutong Geng, Chia-Kuei Mo, Jay Mahsl, Li Ding, Ramaswamy Govindan, Sherri Davies, Jacqueline Mudd, William G Hawkins, Ryan C Fields, David G DeNardo, Jason M Held, Patrick M Grierson, Andrea Wang-Gillam, Marianna B Ruzinova, Kian-Huat Lim, and et al.
Differential cognitive and behavioral development from 6 to 24 months in autism and fragile X syndrome, Lindsay J Mullin, Lisa Flake, Kelly N Botteron, and et al.
Epitope mapping of Japanese encephalitis virus neutralizing antibodies by native mass spectrometry and hydrogen/deuterium exchange, Jagat Adhikari, James Heffernan, Melissa Edeling, Estefania Fernandez, Prashant N Jethva, Michael S Diamond, Daved H Fremont, and Michael L Gross
Mapping human tissues with highly multiplexed RNA in situ hybridization, Kian Kalhor, Amanda Knoten, Joseph P Gaut, Sanjay Jain, and et al.
Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors, James L Shepherdson, Ryan Z Friedman, Yiqiao Zheng, Chi Sun, Inez Y Oh, David M Granas, Barak A Cohen, Shiming Chen, and Michael A White
The latissimus dorsi creates a dynamic track for the inferior angle of the scapula during arm abduction in humans, Alp Paksoy, Doruk Akgün, Henry Gebauer, Daniel Karczewski, Lucca Lacheta, John M Tokish, Aaron Chamberlain, and Philipp Moroder
Predation without direction selectivity, Jenna Krizan, Xiayingfang Song, Michael J Fitzpatrick, Ning Shen, Florentina Soto, and Daniel Kerschensteiner
Prediction of 3-dimensional coverage surface area of the femoral head in hip dysplasia through conventional computed tomography, Tomoyuki Kamenaga, Lucas Ritacco, Pablo A Slullitel, Chadi Nahal, Jeffrey J Nepple, John C Clohisy, and Cecilia Pascual-Garrido
Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial, Patrick Yu-Wai-Man, Gregory Van Stavern, and et al.
Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids, Victoria S Frisbie, Hideharu Hashimoto, Yixuan Xie, Francisca N De Luna Vitorino, Josue Baeza, Tam Nguyen, Zhangerjiao Yuan, Janna Kiselar, Benjamin A Garcia, and Erik W Debler
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species, Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, and Meredith E Jackrel
Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium, Katherine Hrebinko, Vincent P Anto, Katherine M Reitz, Adriana C Gamboa, Scott E Regenbogen, Alexander T Hawkins, M Benjamin Hopkins, Aslam Ejaz, Philip S Bauer, Paul E Wise, Glen C Balch, and Jennifer Holder-Murray
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes, Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P Campbell, David D Chong, Steven Angtuaco, Timothy A Wencewicz, Niraj H Tolia, and Gautam Dantas
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer, Takaomi Hagi, Suwanna Vangveravong, Rony Takchi, Qingqing Gong, S Peter Goedegebuure, Herve Tiriac, Brian A Van Tine, Matthew A Powell, William G Hawkins, and Dirk Spitzer
Treatment setting and buprenorphine discontinuation: An analysis of multi-state insurance claims, Kevin Y Xu, Alex K Gertner, Shelly F Greenfield, Arthur Robin Williams, and Richard A Grucza
Defining clinical endpoints in limb girdle muscular dystrophy: A GRASP-LGMD study, Amy Doody, Lindsay Alfano, Jordi Diaz-Manera, Linda Lowes, Tahseen Mozaffar, Katherine D Mathews, Conrad C Weihl, Matthew Wicklund, Man Hung, Jeffrey Statland, Nicholas E Johnson, and GRASP-LGMD Consortium
Effects of a liquefied petroleum gas stove intervention on stillbirth, congenital anomalies and neonatal mortality: A multi-country Household Air Pollution Intervention Network trial, Ashley Younger, Ashley Toenjes, Lindsay J Underhill, and et al.
Simulation-based analysis of trial design in regional anesthesia, Melisa Pasli, Dmitry Tumin, and Ryan Guffey
AAV gene therapy in companion dogs with severe hemophilia: Real-world long-term data on immunogenicity, efficacy, and quality of life, Bhavya S Doshi, Benjamin J Samelson-Jones, Timothy C Nichols, Elizabeth P Merricks, Joshua L Siner, Robert A French, Ben J Lee, Valder R Arruda, and Mary Beth Callan
Gestational testosterone excess early to mid-pregnancy disrupts maternal lipid homeostasis and activates biosynthesis of phosphoinositides and phosphatidylethanolamines in sheep, Nadia Saadat, Brooke Pallas, Joseph Ciarelli, Arpita Kalla Vyas, and Vasantha Padmanabhan
A phase I trial of pevonedistat in combination with ruxolitinib for the treatment of myelofibrosis, Tim Kong, Nicole Gaudin, Karyn Gordon, Maggie J Cox, Amy W Zhou, and Stephen T Oh
