Submissions from 2021
The dark side of the gut: Virome-host interactions in intestinal homeostasis and disease, Yuhao Li, Scott A. Handley, and Megan T. Baldridge
The Dystonia Coalition: A multicenter network for clinical and translational studies, Gamze Kilic-Berkmen, Laura J Wright, Joel S Perlmutter, Cynthia Comella, Mark Hallett, Jan Teller, Sarah Pirio Richardson, David A Peterson, Carlos Cruchaga, Codrin Lungu, and H A Jinnah
The extensive and functionally uncharacterized mitochondrial phosphoproteome, Natalie M. Niemi and David J. Pagliarini
The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ, Denis A. Kiktev, Margaret Dominska, Tony Zhang, Joseph Dahl, Elena I. Stepchenkova, Piotr Mieczkowski, Peter M. Burgers, Scott Lujan, Adam Burkholder, Thomas A. Kunkel, and Thomas D. Petes
The genetic architecture of a congenital heart defect Is related to Its fitness cost, Ehiole Akhirome, Suk D Regmi, Rachel A Magnan, Nelson Ugwu, Yidan Qin, Claire E Schulkey, James M Cheverud, and Patrick Y Jay
The genomics of heart failure: Design and rationale of the HERMES consortium, R. Thomas Lumbers, Douglas Mann, and et al.
The global Alzheimer's Association round robin study on plasma amyloid β methods, Josef Pannee, Kwasi G Mawuenyega, Vitaliy Ovod, James Bollinger, Randall J Bateman, Yan Li, and et al
The ideological divide in confidence in science and participation in medical research, Matthew Gabel, Jonathan Gooblar, Catherine M. Roe, and John C. Morris
The impact of COVID-19 on dual-physician couples: A disproportionate burden on women physicians, Andrea Soares, Prashanth Thakker, Elena Deych, Shikha Jain, and Rakhee K. Bhayani
The impact of psychological factors and their treatment on the results of total knee arthroplasty, Gregory S Kazarian, Christopher A Anthony, Charles M Lawrie, and Robert L Barrack
The Kanyakla study: Randomized controlled trial of a microclinic social network intervention for promoting engagement and retention in HIV care in rural western Kenya, Matthew D. Hickey, Elvin H. Geng, and et al
The kinase specificity of protein kinase inhibitor peptide, Yao Chen and Bernardo L Sabatini
The next generation of ocular pathogen detection, Sharon L. Sabapathypillai, Hayley R. James, Rachael R. L. Lyerla, and Lynn Hassman
The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity, Anny Gravdal, Xunjun Xiao, Miriam Cnop, Khadija El Jellas, Stefan Johansson, Pål R. Njølstad, Mark E. Lowe, Bente B. Johansson, Anders Molven, and Karianne Fjeld
Therapeutic ultrasound-enhanced immune checkpoint inhibitor therapy, Jinyun Yuan, Dezhuang Ye, Si Chen, and Hong Chen
The risks of stone diagnosis and stone removal procedure after different bariatric surgeries, Steven M. Monda, Joel M. Vetter, Margaret A. Olsen, Matthew R. Keller, J. Christopher Eagon, Michael S. Chevinsky, Vasian Markollari, Ramakrishna Venkatesh, and Alana C. Desai
Thermoneutrality alters gastrointestinal antigen passage patterning and predisposes to oral antigen sensitization in mice, Taeko K Noah, Jee-Boong Lee, Christopher A Brown, Amnah Yamani, Sunil Tomar, Varsha Ganesan, Rodney D Newberry, Gary B Huffnagle, Senad Divanovic, and Simon P Hogan
The role of B cells in primary progressive multiple sclerosis, Jameson P Holloman, Robert C Axtell, Nancy L Monson, and Gregory F Wu
The role of mental imagery in Parkinson's disease rehabilitation, Amit Abraham, Ryan P Duncan, and Gammon M Earhart
The SARM1 TIR NADase: Mechanistic similarities to bacterial phage defense and toxin-antitoxin systems, Aaron DiAntonio, Jeffrey Milbrandt, and Matthew D Figley
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA, Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, and Alex S. Holehouse
The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions, Braulio Bonilla, Hani S. Zaher, Nima Mosammaparast, and et al
The Stroke Neuro-Imaging Phenotype Repository: An open data science platform for stroke research, Hossein Mohammadian Foroushani, Rajat Dhar, Yasheng Chen, Jenny Gurney, Ali Hamzehloo, Jin-Moo Lee, and Daniel S Marcus
The sulfur microbial diet and risk of colorectal cancer by molecular subtypes and intratumoral microbial species in adult men, Daniel R. Sikavi, Yin Cao, and et al
The top 100 cited papers in the field of iron deficiency in humans: A bibliometric study, John L. Frater
The transcriptional landscape of Shh medulloblastoma, Patryk Skowron, Joshua B. Rubin, and et al.
The treatment gap in osteoporosis, Nazia Ayub, Malak Faraj, Sam Ghatan, Joannes A A Reijers, Nicola Napoli, and Ling Oei
The T-type calcium channel isoform Ca v 3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile, Tamara Timic Stamenic, Simon Feseha, Francesca M Manzella, Damon Wallace, Davis Wilkey, Timothy Corrigan, Hanna Fiedler, Patricia Doerr, Kathiresan Krishnan, Yogendra H Raol, Douglas F Covey, Vesna Jevtovic-Todorovic, and Slobodan M Todorovic
The utility of body composition assessment in nutrition and clinical practice: An overview of current methodology, Clifton J Holmes and Susan B Racette
The valproate mediates radio-bidirectional regulation through RFWD3-dependent ubiquitination on Rad51, Guochao Liu, David Lim, Zuchao Cai, Wenwen Ding, Zhujun Tian, Chao Dong, Fengmei Zhang, Gongshe Guo, Xiaowei Wang, Pingkun Zhou, and Zhihui Feng
The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI-3 updates and global perspectives, Christopher J Weber, Richard J Perrin, John C Morris, and et al
Think big, start small: How nanomedicine could alleviate the burden of rare CNS diseases, Abdelfattah Faouzi and Valérie Gaëlle Roullin
Thousands of high‑quality sequencing samples fail to show meaningful correlation between 5S and 45S ribosomal DNA arrays in humans, Ashley N. Hall, Tychele N. Turner, and Christine Queitsch
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses, Nicoletta Caronni, William Vermi, and et al.
Time resolved speckle contrast optical spectroscopy at quasi-null source-detector separation for non-invasive measurement of microvascular blood flow, Marco Pagliazzi, Lorenzo Colombo, Ernesto E. Vidal-Rosas, Tanja Dragojević, Veronika Parfentyeva, Joseph P. Culver, Sanathana Konugolu Venkata Sekar, Laura Di Sieno, Davide Contini, Alessandro Torricelli, Antonio Pifferi, Alberto Dalla Mora, and Turgut Durduran
Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma, Nicholas Cho, Sooah Ko, and Monica Shokeen
TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons, Daxing Gao, Michael S Diamond, and et al
TMS-EEG biomarkers of amnestic mild cognitive impairment due to Alzheimer's disease: A proof-of-concept six years prospective study, Florinda Ferreri, Andrea Guerra, Luca Vollero, David Ponzo, Sara Määtta, Mervi Könönen, Fabrizio Vecchio, Patrizio Pasqualetti, Francesca Miraglia, Ilaria Simonelli, Maurizio Corbetta, and Paolo Maria Rossini
Toll-like receptor signaling in the establishment and function of the immune system, Jahnavi Aluri, Megan A Cooper, and Laura G Schuettpelz
Toward a more comprehensive assessment of school age children with hemiplegic cerebral palsy, Catherine R. Hoyt, Sarah K. Sherman, Shelby K. Brown, Dillan J. Newbold, Ryland L. Miller, Andrew N. Van, Joshua S. Shimony, Mario Ortega, Annie L. Nguyen, Bradley L. Schlaggar, and Nico U.F. Dosenbach
Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress, Yong Fu, Kevin M. Brown, Nathaniel G. Jones, Silvia N.J. Moreno, and L. David Sibley
Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS, Aartik Sarma, Pratik Sinha, and et al
Training LEADers to Accelerate Global Mental Health Disparities Research (LEAD) program: A research training program protocol, Ozge Sensoy Bahar, Patricia Cavazos-Rehg, Fred M Ssewamala, Betsy Abente, Laura Peer, Proscovia Nabunya, Lourdes E Soto de Laurido, Theresa S Betancourt, Arvin Bhana, and Tonya Edmond
Trajectory of long-term outcome in severe pediatric diffuse axonal injury: An exploratory study, Shih-Shan Lang, Todd Kilbaugh, Stuart Friess, Susan Sotardi, Chong Tae Kim, Vanessa Mazandi, Bingqing Zhang, Phillip B Storm, Gregory G Heuer, Alexander Tucker, Steve B Ampah, Heather Griffis, Ramesh Raghupathi, and Jimmy W Huh
Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data, Wanqing Shao and Ting Wang
Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays, Bernard Mulvey and Joseph D. Dougherty
Transcriptome analysis of Dnmt3l knock-out mice derived multipotent mesenchymal stem/stromal cells during osteogenic differentiation, Chih-Yi Yang, Rita Jui-Hsien Lu, Ming-Kang Lee, Felix Shih-Hsian Hsiao, Ya-Ping Yen, Chun-Chun Cheng, Pu-Sheng Hsu, Yi-Tzang Tsai, Shih-Kuo Chen, I-Hsuan Liu, Pao-Yang Chen, and Shau-Ping Lin
Translating family-based behavioral treatment for childhood obesity into a user-friendly digital package for delivery to low-income families through primary care partnerships: The MO-CORD study, Lauren A. Fowler, Sarah E. Hampl, Meredith L. Dreyer Gillette, Amanda E. Staiano, Chelsea L. Kracht, Andrea K. Graham, Sherri Gabbert, Kelly Springstroh, Fanice Thomas, Lisa Nelson, Aubrie E. Hampp, Jordan A. Carlson, Robinson Welch, Denise E. Wilfley, and The MO-CORD Study Group
Transmission dynamics: Data sharing in the COVID-19 era, Randi E Foraker, Albert M Lai, Thomas G Kannampallil, Keith F Woeltje, Anne M Trolard, and Philip R O Payne
TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits antimycobacterial macrophage activation, Ei'ichi Iizasa, Yasushi Chuma, Takayuki Uematsu, Mio Kubota, Hiroaki Kawaguchi, Masayuki Umemura, Kenji Toyonaga, Hideyasu Kiyohara, Ikuya Yano, Marco Colonna, Masahiko Sugita, Goro Matsuzaki, Sho Yamasaki, Hiroki Yoshida, and Hiromitsu Hara
TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis, Jinchao Hou, Yingyue Zhou, Marco Colonna, and et al
Trends in antimicrobial resistance amongst pathogens isolated from blood and cerebrospinal fluid cultures in Pakistan (2011-2015): A retrospective cross-sectional study, Nida Javaid, Qamar Sultana, Karam Rasool, Sumanth Gandra, Fayyaz Ahmad, Safee Ullah Chaudhary, and Shaper Mirza
Tumor-associated neutrophils (TANs) in human carcinoma-draining lymph nodes: A novel TAN compartment, Silvia Lonardi, William Vermi, and et al.
Tumor long interspersed nucleotide element-1 (LINE-1) hypomethylation in relation to age of colorectal cancer diagnosis and prognosis, Naohiko Akimoto, Yin Cao, and et al
TYK2 in cancer metastases: Genomic and proteomic discovery, Dana C Borcherding, Kevin He, Neha V Amin, and Angela C Hirbe
Type 2 diabetes prevention focused on normalization of glycemia: A two-year pilot study, Amy L McKenzie, Shaminie J Athinarayanan, Jackson J McCue, Rebecca N Adams, Monica Keyes, James P McCarter, Jeff S Volek, Stephen D Phinney, and Sarah J Hallberg
Type III interferons: Emerging roles in autoimmunity, Sindhu Manivasagam and Robyn S Klein
UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae, Zachary A. Kemmerer, Kyle P. Robinson, Jonathan M. Schmitz, Mateusz Manicki, Brett R. Paulson, Adam Jochem, Paul D. Hutchins, Joshua J. Coon, and David J. Pagliarini
Ultrasound segmentation-guided edge artifact reduction in diffuse optical tomography using connected component analysis, Shuying Li, Menghao Zhang, and Quing Zhu
Unbiased high-content screening reveals Aβ- and tau-independent synaptotoxic activities in human brain homogenates from Alzheimer's patients and high-pathology controls, Hao Jiang, Thomas J. Esparza, Terrance T. Kummer, and David L. Brody
Understanding drivers of coronavirus disease 2019 (COVID-19) racial disparities: A population-level analysis of COVID-19 testing among black and white populations, Aaloke Mody, Kristin Pfeifauf, Cory Bradley, Branson Fox, Matifadza G. Hlatshwayo, Will Ross, Vetta Sanders-Thompson, Karen Joynt Maddox, Mat Reidhead, Mario Schootman, William G. Powderly, and Elvin H. Geng
Unexpected role of sterol synthesis in RNA stability and translation in Leishmania, Zemfira N Karamysheva, Samrat Moitra, Andrea Perez, Sumit Mukherjee, Elena B Tikhonova, Andrey L Karamyshev, and Kai Zhang
Unfriendly fire: How the tobacco industry is destroying the future of our children, Andrew Bush, Thomas Ferkol, and et al.
Universal masking to control healthcare-associated transmission of severe acute respiratory coronavirus virus 2 (SARS-CoV-2), Eliza R Thompson, Faith S Williams, Pat A Giacin, Shay Drummond, Eric Brown, Meredith Nalick, Qian Wang, Jay R McDonald, and Abigail L Carlson
Universal school meals and associations with student participation, attendance, academic performance, diet quality, food security, and Body Mass Index: A systematic review, Juliana F W Cohen, Amelie A Hecht, Gabriella M McLoughlin, Lindsey Turner, and Marlene B Schwartz
Unmet medical needs and future perspectives for leiomyosarcoma patients-A position paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN), Bernd Kasper, Brian A Van Tine, and et al
Unsupervised cluster analysis of patients with recovered left ventricular ejection fraction identifies unique clinical phenotypes, Andrew Perry, Francis Loh, Luigi Adamo, Kathleen W. Zhang, Elena Deych, Randi Foraker, and Douglas L. Mann
Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy, Udo Fh Engelke, Laura A Jansen, and et al
Use of machine learning to develop and evaluate models using preoperative and intraoperative data to identify risks of postoperative complications, Bing Xue, Dingwen Li, Chenyang Lu, Christopher R. King, Troy Wildes, Michael S. Avidan, Thomas Kannampallil, and Joanna Abraham
Using Lorenz curves to measure racial inequities in COVID-19 testing, Aaloke Mody, Kristin Pfeifauf, and Elvin H. Geng
Using monozygotic twins to dissect common genes in Posttraumatic stress disorder and migraine, Charlotte K Bainomugisa, Heidi G Sutherland, Richard Parker, Allan F Mcrae, Larisa M Haupt, Lyn R Griffiths, Andrew Heath, Elliot C Nelson, Margaret J Wright, Ian B Hickie, Nicholas G Martin, Dale R Nyholt, and Divya Mehta
Using optical coherence tomography and intravascular ultrasound imaging to quantify coronary plaque cap stress/strain and progression: A follow-up study using 3D thin-layer models, Rui Lv, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Caining Zhang, Mengde Huang, Xiaoya Guo, Habib Samady, Don P Giddens, Jie Zheng, Gary S Mintz, and Dalin Tang
Utility of social media for recruitment by orthopaedic surgery residency programs, Alisa Malyavko, Yumin Kim, Tara G. Harmon, Theodore Quan, Alex Gu, Simone A. Bernstein, Sean A. Tabaie, and Savyasachi Thakkar
Vaccines for protecting infants from bacterial causes of diarrheal disease, Richard Walker, Robert W Kaminski, Chad Porter, Robert K M Choy, Jessica A White, James M Fleckenstein, Fred Cassels, and Louis Bourgeois
Validation of diffusion MRI as a biomarker for efficacy using randomized phase III trial of bevacizumab with or without VB-111 in recurrent glioblastoma, Benjamin M Ellingson, Jian L Campian, and et al.
Value of packaged testing for sexually transmitted infections for persons who inject drugs hospitalized with serious injection-related infections, Laura R. Marks, Hilary Reno, Stephen Y. Liang, Evan S. Schwarz, David B. Liss, Linda Jiang, Nathanial S. Nolan, and Michael J. Durkin
Variables associated with intravenous rehydration and hospitalization in children with acute gastroenteritis: A secondary analysis of 2 randomized clinical trials, Naveen Poonai, Philip Tarr, and et al
Veterans Health Administration's Whole Health System of care: Supporting the health, well-being, and resiliency of employees, Kavitha P Reddy, Tamara M Schult, Alison M Whitehead, and Barbara G Bokhour
Video feedback intervention for cognitively impaired older drivers: A randomized clinical trial, Brian R Ott, George D Papandonatos, Erin M Burke, Donna Erdman, David B Carr, and Jennifer D Davis
Viral evasion of innate immune defense: The case of resistance of pandemic H1N1 influenza A virus to human mannose-binding proteins, Mitchell R White, Nikolaos M Nikolaidis, Francis McCormack, Erika C Crouch, and Kevan L Hartshorn
Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells, Vincenza Cifarelli, Sila Appak-Baskoy, Vivek S. Peche, Andrew Kluzak, Trevor Shew, Ramkumar Narendran, Kathryn M. Pietka, Marina Cella, Curtis W. Walls, Rafael Czepielewski, Stoyan Ivanov, Gwendalyn J. Randolph, Hellmut G. Augustin, and Nada A. Abumrad
von Willebrand disease: Proposing definitions for future research, Nathan T. Connell, Jorge Di Paola, and et al.
Weekend light shifts evoke persistent Drosophila circadian neural network desynchrony, Ceazar Nave, Logan Roberts, Patrick Hwu, Jerson D. Estrella, Thanh C. Vo, Thanh H. Nguyen, Tony Thai Bui, Daniel J. Rindner, Nicholas Pervolarakis, Paul J. Shaw, Tanya L. Leise, and Todd C. Holmes
Weight and body mass index change after switching to integrase inhibitors or tenofovir alafenamide among women living with HIV, Cecile D. Lahiri, Jane O'Halloran, and et al
What’s wrong with this picture? A critical review of current Centers for Medicare & Medicaid Services coverage criteria for continuous glucose monitoring, Rodolfo J. Galindo, Christopher G. Parkin, Grazia Aleppo, Anders L. Carlson, Davida F. Kruger, Carol J. Levy, Guillermo E. Umpierrez, and Janet B. McGill
Whipworm-associated intestinal microbiome members consistent across both human and mouse hosts, Bruce A Rosa, Caroline Snowden, John Martin, Kerstin Fischer, Jonah Kupritz, Ethiopia Beshah, Taniawati Supali, Lincoln Gankpala, Peter U Fischer, Joseph F Urban, and Makedonka Mitreva
White matter integrity of contralesional and transcallosal tracts may predict response to upper limb task-specific training in chronic stroke, Daniela J S Mattos, Jerrel Rutlin, Xin Hong, Kristina Zinn, Joshua S Shimony, and Alexandre R Carter
Whole-exome sequencing and hiPSC cardiomyocyte models identify MYRIP, TRAPPC11, and SLC27A6 of potential importance to left ventricular hypertrophy in an African ancestry population, Marguerite R Irvin, Lisa de Las Fuentes, C Charles Gu, Karen Schwander, Dabeeru C Rao, and et al
Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway, Jian Carrot-Zhang, Siddhartha Devarakonda, Wen-Wei Liang, Li Ding, Ramaswamy Govindan, and et al
Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium, Bridget M. Lin, Lisa de Las Fuentes, and et al
Work organization factors associated with health and work outcomes among apprentice construction workers: Comparison between the residential and commercial sectors, Ann Marie Dale, Diane S Rohlman, Lisa Hayibor, and Bradley A Evanoff
Zika virus infection of pregnant Ifnar1-/- mice triggers strain-specific differences in fetal outcomes, Ellie K. Bohm, Jennifer T. Vangorder-Braid, Anna S. Jaeger, Ryan V. Moriarty, John J. Baczenas, Natalie C. Bennett, Shelby L. O'Connor, Michael K. Fritsch, Nicole A. Fuhler, Kevin K. Noguchi, and Matthew T. Aliota
ZO-1 intracellular localization organizes immune response in non-small cell lung cancer, Déborah Neyrinck-Leglantier, Julien Lesage, Silvia Blacher, Arnaud Bonnomet, Walter Hunziker, Agnès Noël, Valérian Dormoy, Béatrice Nawrocki-Raby, Christine Gilles, and Myriam Polette
Submissions from 2020
Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases β-diversity in the gut microbiome of human immunodeficiency virus-exposed, uninfected infants, Alaric W D'Souza, Eshia Moodley-Govender, Bertram Berla, Tejas Kelkar, Bin Wang, Xiaoqing Sun, Brodie Daniels, Anna Coutsoudis, Indi Trehan, and Gautam Dantas
Successful administration of sequential TVEC and pembrolizumab followed by temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation, Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, and George Ansstas
Integrated proteogenomic characterization across major histological types of pediatric brain cancer, Francesca Petralia, Liang-Bo Wang, Li Ding, and et al
A triple-drug treatment regimen to accelerate elimination of lymphatic filariasis: From conception to delivery, Gary J Weil, Julie A Jacobson, and Jonathan D King
CLIP and massively parallel functional analysis of CELF6 reveal a role in destabilizing synaptic gene mRNAs through interaction with 3' UTR elements, Michael A Rieger, Dana M King, Haley Crosby, Yating Liu, Barak A Cohen, and Joseph D Dougherty
Neuroplastin modulates anti-inflammatory effects of MANF, Takuya Yagi, Rie Asada, Kohsuke Kanekura, Ave Eesmaa, Maria Lindahl, Mart Saarma, and Fumihiko Urano
Neutrophil elastase facilitates tumor cell intravasation and early metastatic events, Elena Deryugina, Alexia Carré, Veronica Ardi, Tomoki Muramatsu, Jonas Schmidt, Christine Pham, and James P Quigley
