Open access journal articles published by WashU Medicine faculty in 2020 to the current year.
Submissions from 2020
Bioinspired thermosensitive hydrogel as a vitreous substitute: Synthesis, properties, and progress of animal studies, Amine Laradji, Ying-Bo Shui, Bedia Begum Karakocak, Lynn Evans, Paul Hamilton, and Nathan Ravi
Biomarkers may predict unfavorable neurological outcome after mild traumatic brain injury, Lawrence M. Lewis, Linda Papa, Jeffrey J. Bazarian, Art Weber, Rob Howard, and Robert D. Welch
Blood biomarkers for detection of brain injury in COVID-19 patients, Steven T. DeKosky, Lawrence Lewis, Stacey House, and et al.
Blood pressure profiles in infants with hypoxic ischemic encephalopathy (HIE), response to dopamine, and association with brain injury, Christine Pazandak, Christopher McPherson, Maryam Abubakar, Santina Zanelli, Karen Fairchild, and Zachary Vesoulis
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis, Karla J. Suchacki, Erica L. Scheller, and et al.
Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks, Erin K Moran, James M Gold, Cameron S Carter, Angus W MacDonald, J Daniel Ragland, Steven M Silverstein, Steven J Luck, and Deanna M Barch
BRAF alteration in central and peripheral nervous system tumors, Komal Srinivasa, Kevin A Cross, and Sonika Dahiya
Building access to care in adult sickle cell disease: Defining models of care, essential components, and economic aspects, Julie Kanter, Allison King, and et al.
Cadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions, Timothy J. Wilding and James E. Huettner
Californians Linking Action with Science for Prevention of Breast Cancer (CLASP-BC)-Phase 2, Jon F Kerner, Marion H E Kavanaugh-Lynch, Christopher Politis, Lourdes Baezconde-Garbanati, Aviva Prager, and Ross C Brownson
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening, Po Wei Kang, Annie M Westerlund, Jingyi Shi, Kelli McFarland White, Alex K Dou, Amy H Cui, Jonathan R Silva, Lucie Delemotte, and Jianmin Cui
Campylobacter colonization, environmental enteric dysfunction, stunting, and associated risk factors among young children in rural Ethiopia: A cross-sectional study from the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) project, Dehao Chen, Mark J Manary, and et al
Cancer in Youth Living With HIV (YLWHIV): A narrative review of the access to oncological services among YLWHIV and the role of economic strengthening in child health, Ruth G N Katumba, Ozge Sensoy Bahar, Kimberly J Johnson, and Fred M Ssewamala
Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions, Joseph Ryan Krambs, Grazia Abou Ezzi, Juo-Chin Yao, and Daniel C. Link
Carpal tunnel syndrome among male French farmers and agricultural workers: Is it only associated with physical exposure?, Yves Roquelaure, Sylvaine Jégo, Béatrice Geoffroy-Perez, Emilie Chazelle, Alexis Descatha, Bradley Evanoff, Ronan Garlantézec, and Julie Bodin
Carpal tunnel syndrome and exposure to work-related biomechanical stressors and chemicals: Findings from the Constances cohort, Yves Roquelaure, Ronan Garlantézec, Vincent Rousseau, Alexis Descatha, Bradley Evanoff, Stefano Mattioli, Marcel Goldberg, Marie Zins, and Julie Bodin
Case Report: DSM-5 misses an edge case in tic disorders nosology, Kevin J. Black
Cathepsin S and protease-activated receptor-2 drive alloimmunity and immune regulation in kidney allograft rejection, Yutian Lei, Benjamin Ehle, Santhosh V Kumar, Susanne Müller, Solange Moll, Andrew F Malone, Benjamin D Humphreys, Joachim Andrassy, and Hans-Joachim Anders
CD19 antibody-drug conjugate therapy in DLBCL does not preclude subsequent responses to CD19-directed CAR T-cell therapy, Bicky Thapa, Paolo F. Caimi, Kirit M. Ardeshna, Melhem Solh, Carmelo Carlo-Stella, Brad S. Kahl, and Mehdi Hamadani
CD46 and oncologic interactions: Friendly fire against cancer, Michelle Elvington, M Kathryn Liszewski, and John P Atkinson
CD4 inhibits helper T cell activation at lower affinity threshold for full-length T cell receptors than single chain signaling constructs, Deborah K Johnson, Wyatt Magoffin, Sheldon J Myers, Jordan G Finnell, John C Hancock, Taylor S Orton, Stephen P Persaud, Kenneth A Christensen, and K Scott Weber
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury, Yuhei Kirita, Haojia Wu, Kohei Uchimura, Parker C. Wilson, and Benjamin D. Humphreys
Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis, Sarah Colijn, Vijay Muthukumar, Jun Xie, Siqi Gao, and Courtney T Griffin
Cell type-specific In vitro gene expression profiling of stem cell-derived neural models, James A Gregory, Celeste M Karch, and et al
Cellular diversity of the regenerating caudal fin, Yiran Hou, Hyung Joo Lee, Yujie Chen, Jiaxin Ge, Fujr Osman Ibrahim Osman, Anthony R McAdow, Mayssa H Mokalled, Stephen L Johnson, Guoyan Zhao, and Ting Wang
Cerebral small vessel disease genomics and its implications across the lifespan, Muralidharan Sargurupremraj, Andrew C. Heath, Pamela A.F. Madden, and et al.
Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome, Rachel L Henson, Eric Doran, Bradley T Christian, Benjamin L Handen, William E Klunk, Florence Lai, Joseph H Lee, H Diana Rosas, Nicole Schupf, Shahid H Zaman, Ira T Lott, and Anne M Fagan
Challenges and solutions for the implementation of shared decision-making in breast reconstruction, Terence M. Myckatyn, Rajiv P. Parikh, Clara Lee, and Mary C. Politi
Change in age at diagnosis of oropharyngeal cancer in the United States, 1975-2016, Brittany J Cline, Matthew C Simpson, Matthew Gropler, Aleksandr R Bukatko, Eric Adjei Boakye, Kahee A Mohammed, and Nosayaba Osazuwa-Peters
Characteristics and outcomes among a hospitalized patient cohort with Streptococcus pneumoniae infection, Scott T. Micek, James Simmons, Nicholas Hampton, and Marin H. Kollef
Characterization of a high-resolution breath acetone meter for ketosis monitoring, Donald J Suntrup Iii, Timothy V Ratto, Matt Ratto, and James P McCarter
Characterization of missense mutations in the signal peptide and propeptide of FIX in hemophilia B by a cell-based assay, Wenwen Gao, Yaqi Xu, Hongli Liu, Meng Gao, Qing Cao, Yiyi Wang, Longteng Cui, Rong Huang, Yan Shen, Sanqiang Li, Haiping Yang, Yixiang Chen, Chaokun Li, Haichuan Yu, Weikai Li, and Guomin Shen
Characterization of radiotherapy component impact on MR imaging quality for an MRgRT system, Benjamin C Lewis, Bruce Gu, Ryan Klett, Rajiv Lotey, Olga L Green, and Taeho Kim
Characterization of the complete mitochondrial genomes of two sibling species of parasitic roundworms, Haemonchus contortus and Teladorsagia circumcincta, Nikola Palevich, Paul H Maclean, Young-Jun Choi, and Makedonka Mitreva
Chemical effects of diceCT staining protocols on fluid-preserved avian specimens, Catherine M. Early, Ashley C. Morhardt, Timothy P. Cleland, Christopher M. Milensky, Gwénaëlle M. Kavich, and Helen F. James
Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita, Siddharth Shukla, Ho-Chang Jeong, Christopher M. Sturgeon, Roy Parker, and Luis Francisco Zirnberger Batista
Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration, Jean-Pyo Lee, Edward B. Han, and et al.
Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors, Nicole McAllister, Michael S. Diamond, and et al
Chimerism in the realm of hematopoietic stem cell transplantation for non-malignant disorders-A perspective, Clare Zimmerman and Shalini Shenoy
Chloroquine triggers cell death and inhibits PARPs in cell models of aggressive hepatoblastoma, Katja Eloranta, Stefano Cairo, Emmi Liljeström, Tea Soini, Antti Kyrönlahti, Jean-Gabriel Judde, David B Wilson, Markku Heikinheimo, and Marjut Pihlajoki
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion, Ruochen Zang, James Brett Case, Xiucui Ma, Maria Florencia Gomez Castro, Zhuoming Liu, Qiru Zeng, Haiyan Zhao, Juhee Son, Paul W. Rothlauf, Gaopeng Hou, Michael D. Vahey, Kartik Mani, Daved H. Fremont, Abhinav Diwan, Michael S. Diamond, Sean P.J. Whelan, Siyuan Ding, and et al.
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy, Roxana O Carare, David Holtzman, and et al
Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain, Melanie Y. Pullen, Conrad C. Weihl, and Heather L. True
Clinical and functional significance of circular RNAs in cytogenetically normal AML, Dimitrios Papaioannou, Geoffrey L. Uy, and et al.
Clinical experience of MRI4D QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC, Taeho Kim, Benjamin Lewis, Rajiv Lotey, Enzo Barberi, and Olga Green
Clinical implications of restrictions in criteria for defining surgical site infections after mastectomy, Antoinette A A Bediako-Bowan, David K Warren, Katelin B Nickel, Victoria J Fraser, and Margaret A Olsen
CNS microRNA profles: A database for cell type enriched microRNA expression across the mouse central nervous system, Nathan Pomper, Yating Liu, Mariah L. Hoye, Joseph D. Dougherty, and Timothy M. Miller
Cockayne Syndrome: The many challenges and approaches to understand a multifaceted disease, Alexandre Teixeira Vessoni, Camila Chaves Coelho Guerra, Gustavo Satoru Kajitani, Livia Luz Souza Nascimento, and Camila Carrião Machado Garcia
Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801, Guido Marcucci, Geoffrey L. Uy, and et al.
Combined abdominal heterotopic heart and aorta transplant model in mice, Hao Dun, Li Ye, Yuehui Zhu, and Brian W Wong
Come together: Protein assemblies, aggregates and the sarcostat at the heart of cardiac myocyte homeostasis, Moydul Islam, Abhinav Diwan, and Kartik Mani
Community health behaviors and geographic variation in early-onset colorectal cancer survival among women, Andreana N. Holowatyj, Marvin E. Langston, Yunan Han, Richard Viskochil, Jose Perea, Yin Cao, Charles R. Rogers, Christopher H. Lieu, and Justin X. Moore
Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease, Hemanth R. Nelvagal, Maica Llavero Hurtado, Samantha L. Eaton, Rachel A. Kline, Douglas J. Lamont, Mark S. Sands, Thomas M. Wishart, and Jonathan D. Cooper
Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease, Aylin Dincer, Brian A Gordon, Sarah J Keefe, Shaney Flores, Nicole S McKay, Angela M Paulick, Rebecca L Feldman, Russ C Hornbeck, Beau M Ances, Nelly Joseph-Mathurin, Celeste M Karch, Eric M McDade, Richard J Perrin, Cyrus Raji, Qing Wang, Chengjie Xiong, John C Morris, Randall J Bateman, Tammie L S Benzinger, and et al
Comparing transplant outcomes in ALL patients after haploidentical with PTCy or matched unrelated donor transplantation, Monzr M. Al Malki, Francesca Ferraro, Armin Ghobadi, and et al.
Comparison of differential accessibility analysis strategies for ATAC-seq data, Paul Gontarz, Shuhua Fu, Xiaoyun Xing, Shaopeng Liu, Benpeng Miao, Viktoriia Bazylianska, Akhil Sharma, Pamela Madden, Kitra Cates, Andrew Yoo, Anna Moszczynska, Ting Wang, and Bo Zhang
Comparison of smartphone photography, single-lens reflex photography, and field-grading for trachoma, John M Nesemann, Michael I Seider, Blake M Snyder, Robi N Maamari, Daniel A Fletcher, Berhan A Haile, Zerihun Tadesse, Nicole E Varnado, Sun Y Cotter, Elizabeth Kelly Callahan, Paul M Emerson, Todd P Margolis, Thomas M Lietman, and Jeremy D Keenan
Comparison of the Ekblom-Bak submaximal test to a maximal test in a cohort of healthy younger and older adults in the United States, Stephanie A Schultz, Jennifer Byers, Tammie L S Benzinger, Dominic Reeds, Andrei G Vlassenko, W Todd Cade, and Manu S Goyal
Comparison of three magnetization transfer ratio parameters for assessment of intestinal fibrosis in patients with Crohn’s disease, Jixin Meng, Siyun Huang, CanHui Sun, Zhong-wei Zhang, Ren Mao, Yan-hong Yang, Shi-Ting Feng, Zi-ping Li, and XueHua Li
Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy, Shuang Li, Shixuan Liu, Xiaoran Roger Liu, Mengru Mira Zhang, and Weikai Li
Complications and patient-reported outcomes after TRAM and DIEP flaps: A systematic review and meta-analysis, Waverly Y. He, Leen El Eter, Pooja Yesantharao, Bethany Hung, Haley Owens, Sarah Persing, and Justin M. Sacks
Composite measure of physiological dysregulation as a predictor of mortality: The Long Life Family Study, Konstantin G Arbeev, Olivia Bagley, Svetlana V Ukraintseva, Hongzhe Duan, Alexander M Kulminski, Eric Stallard, Deqing Wu, Kaare Christensen, Mary F Feitosa, Bharat Thyagarajan, Joseph M Zmuda, and Anatoliy I Yashin
Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease, Thomas A. Ray, Martha A. Cady, William J. Spencer, Philip A. Ruzycki, Brian S. Clark, and et al.
Comprehensive profiling of extracellular RNA in HPV‑induced cancers using an improved pipeline for small RNA‑seq analysis, Fangjia Tong, Arlise Andress, Gongyu Tang, Ping Liu, and Xiaowei Wang
Comprehensive validation of halcyon 2.0 plans and the implementation of patient specific QA with multiple detector platforms, Eric Laugeman, Ana Heermann, Jessica Hilliard, Michael Watts, Marshia Roberson, Robert Morris, Sreekrishna Goddu, Abhishek Sethi, Imran Zoberi, Hyun Kim, Sasa Mutic, Geoffrey Hugo, and Bin Cai
Concern of photosensitive seizures evoked by 3D video displays or virtual reality headsets in children: Current perspective, Lawrence Tychsen and Liu Lin Thio
Confidential genetic testing and electronic health records: A survey of current practices among Huntington disease testing centers, Celeste C Eno, Stacey K Barton, Naghmeh Dorrani, Stephen D Cederbaum, Joshua L Deignan, and Wayne W Grody
Considerations in preparative regimen selection to minimize rejection in pediatric hematopoietic transplantation in non-malignant diseases, Robert J Hayashi
Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury, Adam L. Bailey, Liang-I Kang, Luiz Gonzaga Francisco de Assis Barros D'Elia Zanella, Cássia G. T. Silveira, Yeh-Li Ho, Lander Foquet, Greg Bial, Broc T. McCune, Amaro Nunes Duarte-Neto, Archana Thomas, Hans-Peter Raué, Kathleen Byrnes, Esper G. Kallas, Mark K. Slifka, and Michael S. Diamond
Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface, Matthias Garten, Josh R. Beck, Robyn Roth, Tatyana Tenkova-Heuser, John Heuser, Eva S. Istvan, Christopher K.E. Bleck, Daniel E. Goldberg, and Joshua Zimmerberg
Context Is key: Delineating the unique functions of IFNα and IFNβ in disease, Lindsey E Fox, Marissa C Locke, and Deborah J Lenschow
Contraception provision in the emergency department: Are we ready to overcome the obstacles?, Kayleigh Fischer and Lauren S. Chernick
Contribution of aberrant Toll like receptor signaling to the pathogenesis of myelodysplastic syndromes, Luana Chiquetto Paracatu and Laura G Schuettpelz
Contribution of immune cells to glucocorticoid receptor expression in breast cancer, Shipra Gandhi, Ahmed Elkhanany, Masanori Oshi, Tao Dai, Mateusz Opyrchal, Hemn Mohammadpour, Elizabeth A Repasky, and Kazuaki Takabe
Converging on bladder health through design thinking: From an ecology of influence to a focused set of research questions, Jessica B Lewis, Sonya S Brady, Siobhan Sutcliffe, Ariana L Smith, Elizabeth R Mueller, Kyle Rudser, Alayne D Markland, Ann Stapleton, Sheila Gahagan, Shayna D Cunningham, and Prevention Of Lower Urinary Tract Symptoms Plus Research Consortium
Co-occurrence of Campylobacter species in children from eastern Ethiopia, and their association with environmental enteric dysfunction, diarrhea, and host microbiome, Yitagele Terefe, Mark J Manary, Maria Isabel Ordiz, and et al
Core warming of coronavirus disease 2019 (COVID-19) patients undergoing mechanical ventilation-A protocol for a randomized controlled pilot study, Nathaniel Bonfanti, Emily Gundert, Anne M. Drewry, Kristina Goff, Roger Bedimo, and Erik Kulstad
Coronavirus proteins as ion channels: Current and potential research, Conor McClenaghan, Alex Hanson, Sun-Joo Lee, and Colin G Nichols
Critical response to ab interno versus ab externo surgical approach on outflow resistance of a subconjunctival drainage device, Arsham Sheybani, Davinder S. Grover, and Ronald L. Fellman
Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii, Yang Shi, Yueyong Xin, Chao Wang, Robert E Blankenship, Fei Sun, and Xiaoling Xu
Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport, Lucy X. Li, Camaron R. Hole, Javier Rangel-Moreno, Shabaana A. Khader, and Tamara L. Doering
Dangerous liaisons: Interactions of Cryptococcus neoformans with host phagocytes, Elizabeth A Gaylord, Hau Lam Choy, and Tamara L Doering
Deciphering the factors that influence participation in studies requiring serial lumbar punctures, Gregory S Day, Tracy Rappai, Sushila Sathyan, and John C Morris
Deciphering the role of innate immune NF-ĸB pathway in pancreatic cancer, Namrata Khurana, Paarth B Dodhiawala, Ashenafi Bulle, and Kian-Huat Lim
Deconstructing tumor heterogeneity: The stromal perspective, Renee E. Vickman, Douglas V. Faget, Sheila A. Stewart, and et al
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity, Vincenza Cifarelli, Scott C Beeman, Gordon I Smith, Jun Yoshino, Darya Morozov, Joseph W Beals, Brandon D Kayser, Jeramie D Watrous, Mohit Jain, Bruce W Patterson, and Samuel Klein
Deep brain stimulation of the subthalamic nucleus modulates reward-related behavior: A systematic review, Yvan M Vachez and Meaghan C Creed
DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods, Yu He, Hyo Sik Jang, Xiaoyun Xing, Daofeng Li, Michael J Vasek, Joseph D Dougherty, and Ting Wang
Deep learning assessment of breast terminal duct lobular unit involution: Towards automated prediction of breast cancer risk, Suzanne C. Wetstein, Ying Liu, and et al.
Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm, Se-Jin Jeong, Min Ji Cho, Na Young Ko, Sinai Kim, In-Hyuk Jung, Jeong-Ki Min, Sang Hak Lee, Jong-Gil Park, and Goo Taeg Oh
Defining and conceptualizing outcomes for de-implementation: Key distinctions from implementation outcomes, Beth Prusaczyk, Taren Swindle, and Geoffrey Curran
Dementia research in the Caribbean Hispanic islands: Present findings and future trends, Daisy Acosta, Jorge J Llibre-Guerra, Ivonne Z Jiménez-Velázquez, and Juan J Llibre-Rodríguez
Dendritic and parallel processing of visual threats in the retina control defensive responses, T Kim, N Shen, J-C Hsiang, K P Johnson, and D Kerschensteiner
Depletion interactions modulate the binding between disordered proteins in crowded environments, Franziska Zosel, Andrea Soranno, Karin J. Buholzer, Daniel Nettels, and Benjamin Schuler
Deployment of convalescent plasma for the prevention and treatment of COVID-19, Evan M Bloch, Brenda J Grossman, Jeffrey P Henderson, and et al
Depression and nicotine withdrawal associations with combustible and electronic cigarette use, Michele L Pergadia, John W Newcomer, and David G Gilbert
Depressogenic self-schemas are associated with smaller regional grey matter volume in never-depressed preadolescents, Pan Liu, Matthew R J Vandemeer, Marc F Joanisse, Deanna M Barch, David J A Dozois, and Elizabeth P Hayden
Design and rationale of the HAPIN study: A multicountry randomized controlled trial to assess the effect of liquefied petroleum gas stove and continuous fuel distribution, Thomas Clasen, Victor G. Davila-Roman, and et al.
Detecting pneumonia using convolutions and dynamic capsule routing for chest X-ray images, Ansh Mittal, Deepika Kumar, Mamta Mittal, Tanzila Saba, Ibrahim Abunadi, Amjad Rehman, and Sudipta Roy
Determinants of mammographic breast density by race among a large screening population, Justin X. Moore, Yunan Han, Catherine Appleton, Graham Colditz, and Adetunji T. Toriola
