The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2012

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GSK-3β: A bifunctional role in cell death pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, and Dinesh Thotala

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Administration of COG1410 reduces axonal amyloid precursor protein immunoreactivity and microglial activation after controlled cortical impact in mice, Yong Jiang and David L. Brody

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Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer’s disease Ibero-American cohort, Sheng C. Jin, Pau Pastor, Breanna Cooper, Sebastian Cervantes, Bruno A. Benitez, Cristina Razquin, Alison Goate, Ibero-American Alzheimer Disease Genetics Group Researchers, and Carlos Cruchaga

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Antegrade endoscopic removal of retained urethral sling mesh in the bladder, Michael H. Johnson, Genoa G. Ferguson, and Carl G. Klutke

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It's all in the lens: Differences in views on obesity prevention between advocates and policy makers, Ellen Jones, Amy A. Eyler, Leah Nguyen, Jooyoung Kong, Ross C. Brownson, and Jessica H. Bailey

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Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy, Pierre-Emmanuel Joubert, Scott Werneke, Claire de la Calle, Florence Guivel-Benhassine, Alessandra Giodini, Lucie Peduto, Beth Levine, Olivier Schwartz, Deborah Lenschow, and Matthew L. Albert

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Chikungunya virus-induced autophagy delays caspase-dependent cell death, Pierre-Emmanuel Joubert, Scott W. Werneke, Claire de la Calle, Florence Guivel-Benhassine, Alessandra Giodini, Lucie Peduto, Beth Levine, Olivier Schwartz, Deborah J. Lenschow, and Matthew L. Albert

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DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, and Judith L. Campbell

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Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains, Celeste M. Karch, Amanda T. Jeng, Petra Nowotny, Janet Cady, Carlos Cruchaga, and Alison M. Goate

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Heart rate variability changes at 2400 m altitude predicts acute mountain sickness on further ascent at 3000–4300 m altitudes, Heikki M. Karinen, Arja Uusitalo, Henri Vaha-Ypya, Mika Kahonen, Juha E. Peltonen, Phyllis K. Stein, Jari Viik, and Heikki O. Tikkanen

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A multicenter study of Clostridium difficile infection-related colectomy, 2000-2006, Amelia M. Kasper, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Julie E. Mangino, Yosef M. Khan, Bala Hota, Victoria J. Fraser, and Erik R. Dubberke

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Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner, Aparna Kaul, Yi-Hsien Chen, Ryan J. Emnett, Sonika Dahiya, and David H. Gutmann

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Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background, Sharon V. Kawakami-Schulz, Angela M. Verdoni, Shannon G. Sattler, Akihiro Ikeda, and Sakae Ikeda

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Effect of inhaled glucocorticoids in childhood on adult height, H. William Kelly, Alice L. Sternberg, Rachel Lescher, Anne L. Fuhlbrigge, Paul Williams, Robert S. Zeiger, Hengameh H. Raissy, Mark L. Van Natta, James Tonascia, and Robert C. Strunk

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Year in review 2011: Critical Care – neurocritical care, Salah G. Keyrouz and Michael N. Diringer

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Ewing's sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review, Waseem Khaliq, Mohammad Farshad Bahador, Thomas Nichols Laurence, Ronald Andrew Sapiente, James Sheridan Lewis Jr., and David Lee Graham

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The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration, Shyam B. Khatau, Ryan J. Bloom, Saumendra Bajpai, David Razafsky, Shu Zhang, Anjil Giri, Pei-Hsun Wu, Jorge Marchand, Alfredo Celedon, Christopher M. Hale, Sean X. Sun, Didier Hodzic, and Denis Wirtz

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Actin cap associated focal adhesions and their distinct role in cellular mechanosensing, Dong-Hwee Kim, Shyam B. Khatau, Yunfeng Feng, Sam Walcott, Sean X. Sun, Gregory D. Longmore, and Denis Wirtz

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Off-clamp robot-assisted partial nephrectomy for complex renal tumors, Eric H. Kim, Youssef S. Tanagho, Gurdarshan Sandhu, Sam B. Bhayani, and R. Sherburne Figenshau

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A noncomplementation screen for quantitative trait alleles in Saccharomyces cerevisiae, Hyun Seok Kim, Juyoung Huh, Linda Riles, Alejandro Reyes, and Justin C. Fay

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Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis, Jungsu Kim, Adam E M Eltorai, Hong Jiang, Fan Liao, Philip B. Verghese, Jaekwang Kim, Floy R. Stewart, Jacob M. Basak, and David M. Holtzman

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Prefrontal and striatal activity related to values of objects and locations, Soyoun Kim, Xinying Cai, Jaewon Hwang, and Daeyeol Lee

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A role for the membrane Golgi protein Ema in autophagy, Sungsu Kim and Aaron DiAntonio

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Functional consequences of cell type-restricted expression of laminin alpha-5 in mouse placental labyrinth and kidney glomerular capillaries, Sung Tae Kim, Tracy L. Adair-Kirk, Robert M. Senior, and Jefrey H. Miner

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Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli, Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, Scott J. Hultgren, and Amanda L. Lewis

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How do short-term changes at synapses fine-tune information processing?, Achim Klug, J. Gerard G. Borst, Bruce A. Carlson, Cornelia Kopp-Scheinpflug, Vitaly A. Klyachko, and Matthew A. Xu-Friedman

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Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA, Kathryn A. Knoop and Rodney D. Newberry

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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing, Daniel C. Koboldt, Qunyuan Zhang, David E. Larson, Dong Shen, Michael D. McLellan, Ling Lin, Christopher A. Miller, Elaine R. Mardis, Li Ding, and Richard K. Wilson

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A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilatorassociated pneumonia, Marin H. Kollef, Jean Chastre, Marc Clavel, Marcos I. Restrepo, Bart Michiels, Kone Kaniga, Iolanda Cirillo, Holly Kimko, and Rebecca Redman

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Economic impact of ventilator-associated pneumonia in a large matched cohort, Marin H. Kollef, Cindy W. Hamilton, and Frank R. Ernst

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Ubiquitination and degradation of the hominoid- specific oncoprotein TBC1D3 Is mediated by CUL7 E3 ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, and Philip D. Stahl

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Revised sequence and annotation of the Rhodobacter sphaeroides 2.4.1 Genome, Wayne S. Kontur, Wendy S. Schackwitz, Natalia Ivanova, Joel Martin, Kurt LaButti, Shweta Deshpande, Hope N. Tice, Christa Pennacchio, Erica Sodergren, George M. Weinstock, Daniel R. Noguera, and Timothy J. Donohue

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Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection, Maria Kostakioti, Maria Hadjifrangiskou, Corinne K. Cusumano, Thomas J. Hannan, James W. Janetka, and Scott J. Hultgren

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Challenging presentations of cavernous sinus thrombophlebitis, Courtney L. Kraus and Susan M. Culican

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Small media and client reminders for colorectal cancer screening: Current use and gap areas in CDC's colorectal cancer control program, Matthew W. Kreuter, Lori B. Garibay, Debbie J. Pfeiffer, Jennifer C. Morgan, Melonie Thomas, Katherine M. Wilson, Jennifer Pieters, Kellie Szczepaniec, Amy Scott, and Timothy J. Poor

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Polygenic threshold model with sex dimorphism in adolescent idiopathic scoliosis: The Carter effect, Lisa M. Kruse, Jillian G. Buchan, Christina A. Gurnett, and Matthew B. Dobbs

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Rehabilitation after anterior cruciate ligament reconstruction: A systematic review, L. M. Kruse, B. Gray, and R. W. Wright

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The L.E.A.D. framework: Using tools from evidence-based public health to address evidence needs for obesity prevention, Shiriki Kumanyika, Ross C. Brownson, and Allen Cheadle

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Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma, Rachel L. Kyllo, Youssef S. Tanagho, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Shahab P. Hillyer, Shyam S. Sukumar, Kenneth G. Nepple, and Sam B. Bhayani

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Observational Research in Childhood Infectious Diseases (ORChID): A dynamic birth cohort study, Stephen Bernard Lambert, Robert S. Ware, Anne L. Cook, Frances A. Maguire, David M. Whiley, Seweryn Bialasiewicz, Ian M. Mackay, David Wang, Theo P. Sloots, Michael D. Nissen, and Keith Grimwood

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Paragonimus kellicotti Fluke infections in Missouri, USA, Michael A. Lane, Mary C. Barsanti, Carlos A. Santos, Michael Yeung, Sam J. Lubner, and Gary J. Weil

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Beyond 30 days: Does limiting the duration of surgical site infection follow-up limit detection?, Julie D. Lankiewicz, Deborah S. Yokoe, Margaret A. Olsen, Fallon Onufrak, Victoria J. Fraser, Kurt Stevenson, Yosef Khan, David Hooper, Richard Platt, and Susan S. Huang

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Multiscale forward electromagnetic model of uterine contractions during pregnancy, Patricio S. La Rosa, Hari Eswaran, Hubert Preissl, and Arye Nehorai

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Ybcl of uropathogenic escherichia coli suppresses transepithelial neutrophil migration, Megan E. Lau, Jennifer A. Loughman, and David A. Hunstad

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AHR and the transcriptional regulation of Type-17/22 ILC, Jacob S. Lee, Marina Cella, and Marco Colonna

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Clustering of resting state networks, Megan H. Lee, Carl D. Hacker, Abraham Z. Snyder, Maurizio Corbetta, Dongyang Zhang, Eric C. Leuthardt, and Joshua S. Shimony

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Natural killer cell regulation by microRNAs in health and disease, Jeffrey W. Leong, Ryan P. Sullivan, and Todd A. Fehniger

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Temporal evolution of gamma activity in human cortex during an overt and covert word repetition task, Eric C. Leuthardt, Xiao-Mei Pei, Jonathan Breshears, Charles Gaona, Mohit Sharma, Zac Freudenberg, Dennis Barbour, and Gerwin Schalk

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Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi, Ben-Wen Li, Zhengyuan Wang, Amy C. Rush, Makedonka Mitreva, and Gary J. Weil

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The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses, Efrem S. Lim, Lily I. Wu, Harmit S. Malik, and Michael Emerman

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Political and social determinants of life expectancy in less developed countries: A longitudinal study, Ro-Ting Lin, Ya-Mei Chen, Lung-Chang Chien, and Chang-Chuan Chan

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DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, and Jing Zhang

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Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, and Alexander S. Krupnick

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Compound heterozygous mutations in the SUR1 (ABCC 8) subunit of pancreatic KATP channels cause neonatal diabetes by perturbing the coupling between Kir6.2 and SUR1 subunits, Yu-Wen Lin, Alejandro Akrouh, YeouChing Hsu, Nkecha Hughes, Colin G. Nichols, and Diva D. De Leon

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Correlations of coronary plaque wall thickness with wall pressure and wall pressure gradient: A representative case study, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang

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CHFR is important for the first wave of ubiquitination at DNA damage sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, and Xiaochun Yu

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Intravital 2-photon imaging of leukocyte trafficking in beating heart, Wenjun Li, Ruben G. Nava, Alejandro C. Bribriesco, Bernd H. Zinselmeyer, Jessica H. Spahn, Andrew E. Gelman, Alexander S. Krupnick, Mark J. Miller, and Daniel Kreisel

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The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel, Lipin Loo, Andrew J. Shepherd, Aaron D. Mickle, Ramon A. Lorca, Leonid P. Shutov, Yuriy M. Usachev, and Durga P. Mohapatra

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Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts, Catherine Lozupone, Karoline Faust, Jeroen Raes, Jeremiah J. Faith, Daniel N. Frank, Jesse Zaneveld, Jeffrey I. Gordon, and Rob Knight

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The association of neonatal dacryocystoceles and infantile dacryocystitis with nasolacrimal duct cysts (an American Ophthalmogical Society Thesis), Gregg T. Lueder

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An Australian twin study of cannabis and other illicit drug use and misuse, and other psychopathology, Michael T. Lynskey, Arpana Agrawal, Anjali Henders, Elliot C. Nelson, Pamela A.F. Madden, and Nicholas G. Martin

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Re-orientation of clinical research in traumatic brain injury: Report of an international workshop on comparative effectiveness research, Andrew I.R. Maas, David K. Menon, Hester F. Lingsma, Jose A. Pineda, M. Elizabeth Sandel, and Geoffery T. Manley

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Splint: The efficacy of orthotic management in rest to prevent equinus in children with cerebral palsy, a randomised controlled trial, Josina C. Maas, Annet J. Dallmeijer, Peter A. Huijing, Janice E. Brunstrom-Hernandez, Petra J. van Kampen, Richard T. Jaspers, and Jules G. Becher

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Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models, Cynthia X. Ma, Shirong Cai, Shunqiang Li, Christine E. Ryan, Zhangfang Guo, W. Timothy Schaiff, Li Lin, Jeremy Hoog, Reece J. Goiffon, Aleix Prat, Rebecca L. Aft, Matthew J. Ellis, and Helen Piwnica-Worms

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Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion, P. A. F. Madden, A. C. Heath, and et al

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Diazoxide maintains human myocyte volume homeostasis during stress, Sara K. Maffit, Angela D. Sellitto, Ashraf S. Al-Dadah, Richard B. Schuessler, Ralph J. Damiano Jr., and Jennifer S. Lawton

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Putative factors that may modulate the effect of exercise on liver fat: Insights from animal studies, Faidon Magkos

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A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis, Alena V. Makarova, Joseph L. Stodola, and Peter M. Burgers

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Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages, Nicole S. Maloney, Larissa B. Thackray, Gautam Goel, Seungmin Hwang, Erning Duan, Punit Vachharajani, Ramnik Xavier, and Herbert W. Virgin

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Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness, Daniel Mamah, Michael P. Harms, Deanna Barch, Martin Styner, Jeffrey A. Lieberman, and Lei Wang

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Warfarin and aspirin in patients with heart failure and sinus rhythm, Douglas L. Mann and et al

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Short report: Genetic characterization of atypical Mansonella (Mansonella) ozzardi microfilariae in human blood samples from Northeastern Peru, Luis A. Marcos, Nancy Arrospide, Sergio Recuenco, Cesar Cabezas, Gary J. Weil, and Peter U. Fischer

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Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data, Elaine R. Mardis, Richard K. Wilson, and et al

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The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K+ channels, Céline Marionneau, Yarimar Carrasquillo, Aaron J. Norris, R. Reid Townsend, Lori L. Isom, Andrew J. Link, and Jeanne M. Nerbonne

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Mapping a complete neural population in the retina, Olivier Marre, Dario Amodei, Nikhil Deshmukh, Kolia Sadeghi, Frederick Soo, Timothy E. Holy, and Michael J. Berry

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Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data, John Martin, Sahar Abubucker, Esley Heizer, Christina M. Taylor, and Makedonka Mitreva

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Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities, John Martin, Sean Sykes, Sarah Young, Karthik Kota, Ravi Sanka, Nihar Sheth, Joshua Orvis, Erica Sodergren, Zhengyuan Wang, George M. Weinstock, and Makedonka Mitreva

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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death, Xiucui Ma, Rebecca J. Godar, Haiyan Liu, and Abhinav Diwan

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Autophagy is impaired in cardiac ischemia-reperfusion injury, Xiucui Ma, Haiyan Liu, Sarah R. Foyil, Rebecca J. Godar, Carla J. Weinheimer, and Abhinav Diwan

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Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus, Zhongmin Alex Ma, Zhengshan Zhao, and John Turk

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Recognizing and managing the expanded risk of tumor lysis syndrome in hematologic and solid malignancies, Ali McBride and Peter Westervelt

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Structural mechanism of ER retrieval of MHC class I by cowpox, William H. McCoy IV, Xiaoli Wang, Wayne M. Yokoyama, Ted H. Hansen, and Daved H. Fremont

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Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing, Emily C. McCusker, Claire Bagnéris, Claire E. Naylor, Ambrose R. Cole, Nazzareno D'Avanzo, Colin G. Nichols, and B A. Wallace

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Environmental influences predominate in remission from alcohol use disorder in young adult twins, V. V. McCutcheon, J. D. Grant, A. C. Heath, K. K. Bucholz, C. E. Sartor, E. C. Nelson, P. A F Madden, and N. G. Martin

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Automated web-based request mechanism for workflow enhancement in an academic customer-focused biorepository, Sandra A. McDonald, Benjamin J. Ryan, Amy Brink, and Victoria L. Holtschlag

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Fee-for-service as a business model of growing importance: the academic biobank experience, Sandra A. McDonald, Kara Sommerkamp, Maureen Egan-Palmer, Karen Kharasch, and Victoria Holtschlag

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Vascular anatomy of the tibiofibular syndesmosis, Kathleen E. McKeon, Rick W. Wright, Jeffrey E. Johnson, Jeremy J. McCormick, and Sandra E. Klein

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Lack of short-term effectiveness of rotating treadmill training on turning in people with mild-to-moderate Parkinson's disease and healthy older adults: A randomized, controlled study, Marie E. McNeely and Gammon M. Earhart

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Transcriptomic and proteomic analyses of a Wolbachia- free filarial parasite provide evidence of trans-kingdom horizontal gene transfer, Samantha N. McNulty, Sahar Abubucker, Gabriel M. Simon, Makedonka Mitreva, Nathan P. McNulty, Kerstin Fischer, Kurt C. Curtis, Norbert W. Brattig, Gary J. Weil, and Peter U. Fischer

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Comparing the mitochondrial genomes of Wolbachia-dependent and independent filarial nematode species, Samantha N. McNulty, Andrew S. Mullin, Jefferson A. Vaughan, Vasyl V. Tkach, Gary J. Weil, and Peter U. Fischer

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What would make getting colorectal cancer screening easier? Perspectives from screeners and nonscreeners, Gilda G. Medina, Amy McQueen, Anthony J. Greisinger, L. Kay Bartholomew, and Sally W. Vernon

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When planning results in loss of control: Intention-based reflexivity and working-memory, Nachshon Meiran, Michael W. Cole, and Todd S. Braver

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Progression from sustained BK viruria to sustained BK viremia with immunosuppression reduction is not associated with changes in the noncoding control region of the BK virus genome, Imran A. Memon, Bijal A. Parikh, Monique Gaudreault-Keener, Rebecca Skelton, Gregory A. Storch, and Daniel C. Brennan

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An analysis of the transcriptome of Teladorsagia circumcincta: Its biological and biotechnological implications, Ranjeeta Menon, Robin B. Gasser, Makedonka Mitreva, and Shoba Ranganathan

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An institutional perspective on the impact of recent antibiotic exposure on length of stay and hospital costs for patients with gram-negative sepsis, Scott Micek, Michael T. Johnson, Richard Reichley, and Marin H. Kollef

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Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint, Alexander P. Miceli, Anthony J. Saporita, and Jason D. Weber

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The business case for a diabetes self-management intervention in a community general hospital, Ashley Micklethwaite, Carol A. Brownson, Mary L. O'Toole, and Kerry E. Kilpatrick

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Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein, Rita PS Middelberg, Andrew C. Heath, Pamela AF Madden, Grant W. Montgomery, Nicholas G. Martin, and John B. Whitfield

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Deciphering a global network of functionally associated post-translational modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera van Noort, and Peer Bork

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Quantitative trait loci affecting liver fat content in mice, Olga Minkina, James M. Cheverud, Gloria Fawcett, Clay F. Semenkovich, and Jane P. Kenney-Hunt