The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2010
Charting the progression of disability in Parkinson disease: Study protocol for a prospective longitudinal cohort study, Leland E. Dibble, James T. Cavanaugh, Gammon M. Earhart, Terry D. Ellis, Matthew P. Ford, and Kenneth B. Foreman
Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells, Hans H. Dietrich, Chuanxi Xiang, Byung H. Han, Gregory J. Zipfel, and David M. Holtzman
Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern, Deborah E. Dobson, Shaden Kamhawi, Phillip Lawyer, Salvatore J. Turco, Stephen M. Beverley, and David L. Sacks
It's not easy being green: The viridans group streptococci, with a focus on pediatric clinical manifestations, Christpher D. Doern and Carey-Ann D. Burnham
Self versus environment motion in postural control, Kalpana Dokka, Robert V. Kenyon, Emily A. Keshner, and Konrad P. Kording
Remember the source: Dissociating frontal and parietal contributions to episodic memory, David I. Donaldson, Mark E. Wheeler, and Steve E. Petersen
Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure, Gerald W. Dorn II
Cerenkov radiation energy transfer (CRET) imaging: A novel method for optical imaging of PET isotopes in biological systems, Robin S. Dothager, Reece J. Goiffon, Erin Jackson, Scott Harpstrite, and David Piwnica-Worms
Magnesium induces neuronal apoptosis by suppressing excitability, W. H. Dribben, L. N. Eisenman, and S. Mennerick
Prevention of healthcare-associated Clostridium difficile infection: What works?, Erik R. Dubberke
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin, Alexis Dumortier, Andre-Dante Durham, Matteo Di Piazza, Sophie Vauclair, Ute Koch, Gisele Ferrand, Isabel Ferrero, Shadmehr Demehri, Lynda Li Song, Andrew G. Farr, Warren J. Leonard, Raphael Kopan, Lucio Miele, Daniel Hohl, Daniel Finke, and Freddy Radtke
Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice, Ildiko R. Dunay, Anja Fuchs, and L. David Sibley
Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice, Matthew D. Dunn, Shannon L. Rossi, Donald M. Carter, Matthew R. Vogt, Erin Mehlhop, Michael S. Diamond, and Ted M. Ross
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow, Kyle J. Eash, Adam M. Greenbaum, Priya K. Gopalan, and Daniel C. Link
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells, Brian T. Edelson, Wumesh KC, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun-Sang J. Sung, Theresa L. Murphy, Kai Hildner, and Kenneth M. Murphy
Improving prefrontal cortex function in schizophrenia through focused training of cognitive control, Bethany G. Edwards, Deanna M. Barch, and Todd S. Braver
Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns, John R. Edwards, Anne H. O'Donnell, Robert A. Rollins, Heather E. Peckham, Clarence Lee, Maria H. Milekic, Benjamin Chanrion, Yutao Fu, Tao Su, Hanina Hibshoosh, Jay A. Gingrich, Fatemeh Haghighi, Robert Nutter, and Timothy H. Bestor
p38δ mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis, Tatiana Efimova
Multiple pathways of inhibition shape bipolar cell responses in the retina, Erika D. Eggers and Peter D. Lukasiewicz
MHC class I–deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I–sufficient environment, Julie M. Elliott, Joseph A. Wahle, and Wayne M. Yokoyama
Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism, Laura A. Engel, Zheng Jing, Daniel E. O’Brien, Mengyang Sun, and Paul T. Kotzbauer
Gene-expression profiling for rejection surveillance after cardiac transplantation, Gregory A. Ewald and et al
Next-generation sequencing identifies the natural killer cell microRNA transcriptome, Todd A. Fehniger, Todd Wylie, Elizabeth Germino, Jeffrey W. Leong, Vincent J. Magrini, Sunita Koul, Catherine R. Keppel, Stephanie E. Schneider, Daniel C. Koboldt, Ryan P. Sullivan, Michael E. Heinz, Seth D. Crosby, Rakesh Nagarajan, Giridharan Ramsingh, Daniel C. Link, Timothy J. Ley, and Elaine R. Mardis
Multiplexed echo planar imaging for sub-second whole brain fMRI and fast diffusion imaging, David A. Feinberg, Steen Moeller, Stephen M. Smith, Edward Auerbach, Sudhir Ramanna, Matt F. Glasser, Karla L. Miller, Kamil Ugurbil, and Essa Yacoub
Major depression and the metabolic syndrome, Debra L. Foley, Katherine I. Morley, Pamela A.F. Madden, Andrew C. Heath, John B. Whitfield, and Nicholas G. Martin
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells, Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, and Fumihiko Urano
Structural homology between the C-terminal domain of the PapC usher and its plug, Bradley Ford, Ana Toste Rêgo, Timothy J. Ragan, Jerome Pinkner, Karen Dodson, Paul C. Driscoll, Scott Hultgren, and Gabriel Waksman
Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial, Benjamin French, Jungnam Joo, Nancy L. Geller, Stephen E. Kimmel, Yves Rosenberg, Jeffrey L. Anderson, Brian F. Gage, Julie A. Johnson, Jonas H. Ellenberg, and COAG Investigators
Age-related synaptic loss of the medial olivocochlear efferent innervation, Benjamin Fu, Colleen Le Prell, Dwayne Simmons, Debin Lei, Angela Schrader, Amelia B. Chen, and Jianxin Bao
Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo LaDu, and Guojun Bu
VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans, Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M. Barnett, and Wojciech Swat
Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes, Kei Fujimoto, Eric L. Ford, Hung Tran, Burton M. Wice, Seth D. Crosby, Gerald W. Dorn II, and Kenneth S. Polonsky
The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy, Brian M. Fuller, Mithil Gajera, Christa Schorr, David Gerber, R. Phillip Dellinge, Joseph Parrillo, and Sergio Zanotti
Parallel input channels to mouse primary visual cortex, Enquan Gao, Gregory C. DeAngelis, and Andreas Burkhalter
Identification of hookworm DAF-16/FOXO response elements and direct gene targets, Xin Gao, Zhengyuan Wang, John Martin, Sahar Abubucker, Xu Zhang, Makedonka Mitreva, and John M. Hawdon
Reliability of job-title based physical work exposures for the upper extremity: comparison to self-reported and observed exposure estimates, Bethany T. Gardner, David A. Lombardi, Ann Marie Dale, Alfred Franzblau, and Bradley A. Evanoff
To-and-fro murmur in the young due to major congenital cardiac defects: Is cardiac auscultation obsolete?, Avihu Z. Gazit, Gautam K. Singh, and Mark C. Johnson
Dyskerin ablation in mouse liver inhibits rRNA processing and cell division, Jingping Ge, David A. Rudnick, Jun He, Dan L. Crimmins, Jack H. Ladenson, Monica Bessler, and Philip J. Mason
Orthopaedic surgeons and the medical device industry: The threat to scientific integrity and the public trust, Richard H. Gelberman, David Samson, Sohail K. Mirza, John J. Callaghan, and Vincent D. Pellegrini
Gene–environment interactions at nucleotide resolution, Justin Gerke, Kim Lorenz, Shelina Ramnarine, and Barak Cohen
Multicenter study of clinical performance of the 3M rapid detection RSV test, Christine C. Ginocchio, Ella Swierkosz, Alexander J. McAdam, Mario Marcon, Gregory A. Storch, Alexandra Valsamakis, Stefan Juretschko, José Romero, and Belinda Yen-Lieberman
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, and Marco Colonna
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease, Alison M. Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, and et al.
RET signaling is required for survival and normal function of nonpeptidergic nociceptors, Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau IV, Eugene M. Johnson Jr, and Sanjay Jain
Human mucosal associated invariant T cells detect bacterially infected cells, Marielle C. Gold, Stefanie Cerri, Susan Smyk-Pearson, Meghan E. Cansler, Todd M. Vogt, Jacob Delepine, Ervina Winata, Gwendolyn M. Swarbrick, Wei-Jen Chua, Yik Y. L. Yu, Olivier Lantz, Matthew S. Cook, Megan D. Null, David B. Jacoby, Melanie J. Harriff, Deborah A. Lewinsohn, Ted H. Hansen, and David M. Lewinsohn
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation, Veronica Gomez-Godinez, Tao Wu, Adria J. Sherman, Christopher S. Lee, Lih-Huei Liaw, You Zhongsheng, Kyoko Yokomori, and Michael W. Berns
Multiple interaction domains in FtsL, a protein component of the widely conserved bacterial FtsLBQ cell division complex, Mark D. Gonzalez, Esra A. Akbay, Dana Boyd, and Jon Beckwith
Nurturing the genome: A-type lamins preserve genomic stability, Ignacio Gonzalez-Suarez and Susana Gonzalo
Sit and Stay a While: How BfiSR Controls Irreversible Attachment in Pseudomonas aeruginosa Biofilms, Andrew L. Goodman
The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin, Susan Grass, Cheryl F. Lichti, R. Reid Townsend, Julia Gross, and Joseph W. St. Geme III
Developmental origin of preBötzinger complex respiratory neurons, Paul A. Gray, John A. Hayes, Guang Y. Ling, Isabel Llona, Srinivasan Tupal, Maria C.D. Picardo, Sarah E. Ross, Tsutomu Hirata, Joshua G. Corbin, Jaime Eugenín, and Christopher A. Del Negro
Brain specificity of diffuse optical imaging: improvements from superficial signal regression and tomography, Nicholas M. Gregg, Brian R. White, Benjamin W. Zeff, Andrew J. Berger, and Joseph P. Culver
Serological evidence of human klassevirus infection, Alexander L. Greninger, Lori Holtz, Gagandeep Kang, Donald Ganem, David Wang, and Joseph L. DeRisi
Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy, Naomi Gronich, Azad Kumar, Yuwei Zhang, Igor R. Efimov, and Nikolai M. Soldatov
Vesicular neurotransmitter transporter trafficking in vivo: Moving from cells to flies, Anna Grygoruk, Hao Fei, Richard W. Daniels, Bradley R. Miller, Audrey Chen, Aaron DiAntonio, and David E. Krantz
Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections, Pascale S. Guiton, Chia S. Hung, Lynn E. Hancock, Michael G. Caparon, and Scott J. Hultgren
Histone modifications during mammalian oocyte maturation: Dynamics, regulation and functions, Ling Gu, Qiang Wang, and Qing-Yuan Sun
Construction of recombinant attenuated Salmonella enterica serovar typhimurium vaccine vector strains for safety in newborn and infant mice, Bronwyn M. Gunn, Soo-Young Wanda, Dana Burshell, Caihong Wang, and Roy Curtiss III
The effects of a secondary task on forward and backward walking in Parkinson’s disease, Madeleine E. Hackney and Gammon M. Earhart
A monoclonal antibody toolkit for C. elegans, Gayla Hadwiger, Scott Dour, Swathi Arur, Paul Fox, and Michael L. Nonet
Organogenetic tolerance, Marc R. Hammerman
Evaluation and management of inherited disorders of surfactant metabolism, Aaron Hamvas
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection, Thomas J. Hannan, Indira U. Mysorekar, Chia S. Hung, Megan L. Isaacson-Schmid, and Scott J. Hultgren
Current strategies for the prevention and management of central line-associated bloodstream infections, Zhuolin Han, Stephen Y. Liang, and Jonas Marschall
Defining the plasticity of transcription factor binding sites by deconstructing DNA consensus sequences: The PhoP-binding sites among gamma/enterobacteria, Oscar Harari, Sun-Yang Park, Henry Huang, Eduardo A. Groisman, and Igor Zwir
Thymoglobulin induction dosing strategies in a low-risk kidney transplant population: Three or four days?, Karen L. Hardinger, Rafia S. Rasu, Rebecca Skelton, Brent W. Miller, and Daniel C. Brennan
Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step, Brooke Harmon, Nancy Campbell, and Lee Ratner
Do race-specific definitions of short long bones improve the detection of Down syndrome on second-trimester genetic sonograms?, Lorie M. Harper
Development and preliminary reliability testing of an assessment of patient independence in performing a treatment program: Standardized scenarios, Marcie Harris-Hayes, Gregory W. Holtzman, Jeanne A. Earley, and Linda R. Van Dillen
Wormbase: A comprehensive resource for nematode research, Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri, Darin Blasiar, Juancarlos Chan, Wen J. Chen, Norie De La Cruz, Paul Davis, Margaret Duesbury, Ruihua Fang, Jolene Fernandes, Michael Han, Ranjana Kishore, Raymond Lee, Hans-Michael Muller, Cecilia Nakamura, Philip Ozersky, Andrei Petcherski, Arun Rangarajan, Anthony Rogers, Gary Schindelman, Erich M. Schwarz, Mary Ann Tuli, Kimberly Van Auken, Daniel Wang, Xiaodong Wang, Gary Williams, Karen Yook, Richard Durbin, Lincoln D. Stein, John Spieth, and Paul W. Sternberg
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice, Björn Hartleben, Markus Gödel, Catherine Meyer-Schwesinger, Shuya Liu, Theresa Ulrich, Sven Köbler, Thorsten Wiech, Florian Grahammer, Andrey S. Shaw, Noburu Mizushima, Dontscho Kerjaschki, Hermann Pavenstadt, Clemens D. Cohen, Maja T. Lindenmeyer, Sebastian J. Arnold, and et al
Robot-assisted partial nephrectomy: Evaluation of learning curve for an experienced renal surgeon, Mohammed Haseebuddin, Brian M. Benway, Jose M. Cabello, and Sam B. Bhayani
Golgi cells operate as state-specific temporal filters at the input stage of the cerebellar cortex, Shane A. Heine, Stephen M. Highstein, and Pablo M. Blazquez
A surface-based analysis of hemispheric asymmetries and folding of cerebral cortex in term-born human infants, Jason Hill, Donna Dierker, Jeffrey Neil, Terrie Inder, Andrew Knutsen, John Harwell, Timothy Coalson, and David Van Essen
Reducing the incidence of intraventricular catheter-related ventriculitis in the neurology-neurosurgical intensive care unit at a tertiary care center in St Louis, Missouri: An 8-year follow-up study, Hitoshi Honda, Jeffrey C. Jones, Martha C. Craighead, Michael N. Diringer, Ralph G. Dacey, and David K. Warren
The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine, John R. Hornick, Jinbin Xu, Suwanna Vangveravong, Zhude Tu, Jonathan B. Mitchem, Dirk Spitzer, Peter Goedegebuure, Robert H. Mach, and William G. Hawkins
Immunotherapy for sepsis - A new approach against an ancient foe, Richard S. Hotchkiss and Steven Opal
Sliding set-points of immune responses for therapy of autoimmunity, Chyi-Song Hsieh and Jhoanne Lynne Bautista
Aldo-keto reductases in the eye, Shun Ping Huang, Suryanarayana Palla, Philip Ruzycki, Ross Arjun Varma, Theresa Harter, G. Bhanuprakesh Reddy, and J. Mark Petrash
Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice, Chunxiu Hu, Miriam Hoene, Xinjie Zhao, Hans U. Haring, Erwin Schleicher, Rainer Lehmann, Xianlin Han, Guowang Xu, and Cora Weigert
Reproducibility of placental volume and vasculature indices obtained by 3-dimensional power Doppler sonography, Kristina M. Huster, Kimberly Haas, Jean Schoenborn, Dominique McVean, and Anthony O. Odibo
Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization, Yuji Ito, Steven L. Teitelbaum, Wei Zou, Yi Zheng, James F. Johnson, Jean Chappel, F. Patrick Ross, and Haibo Zhao
Deep sequencing of small RNA libraries reveals dynamic regulation of conserved and novel microRNAs and microRNA-stars during silkworm development, Guru Jagadeeswaran, Yun Zheng, Niranji Sumathipala, Haobo Jiang, Estela L. Arrese, Jose L. Soulages, Weixiong Zhang, and Ramanjulu Sunkar
Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice, Sanjay Jain, Amanda Knoten, Masato Hoshi, Hongtao Wang, Bhupinder Vohra, Robert O. Heuckeroth, and Jeffrey Milbrandt
Short-term signatures of evolutionary change in the Salmonella enterica serovar Typhimurium 14028 genome, Tyler Jarvik, Chris Smillie, Eduardo A. Groisman, and Howard Ochman
A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing, Xiaoping Jiang, Patricia E. Litkowski, Amanda A. Taylor, Ying Lin, B. J. Snider, and Krista L. Moulder
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination, Yanhong Ji, Alicia J. Little, Joydeep K. Banerjee, Bingtao Hao, Eugene M. Oltz, Michael S. Krangel, and David G. Schatz
Hidden Markov model speed heuristic and iterative HMM search procedure, L Steven Johnson, Sean R. Eddy, and Elon Portugaly
Controlled release of neurotrophin-3 and platelet-derived growth factor from fibrin scaffolds containing neural progenitor cells enhances survival and differentiation into neurons in a subacute model of SCI, Philip J. Johnson, Alexander Tatara, Alicia Shu, and Shelly E. Sakiyama-Elbert
Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function, Jyh-Ming Jimmy Juang, Lisa de las Fuentes, Alan D. Waggoner, C Charles Gu, and Victor G. Davila-Roman
Quantitation of "autophagic flux" in mature skeletal muscle, Jeong-Sun Ju, Arun S. Varadhachary, Sara E. Miller, and Conrad C. Weihl
p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system, Jeong-Sun Ju and Conrad C. Weihl
Evaluation of a chromogenic agar under development to screen for VRE colonization, George Kallstrom, Christopher D. Doern, and W. Michael Dunne Jr.
The role of presynaptic dynamics in processing of natural spike trains in hippocampal synapses, Umasankar Kandaswamy, Pan-Yue Deng, Charles F. Stevens, and Vitaly A. Klyachko
Virulence gene regulation by CvfA, a putative RNase: The CvfA-enolase complex in Streptococcus pyogenes links nutritional stress, growth-phase control, and virulence gene expression, Song Ok Kang, Michael G. Caparon, and Kyu Hong Cho
Consumers’ use of web-based information and their decisions about multiplex genetic susceptibility testing, Kimberly A. Kaphingst, Colleen M. McBride, Christopher Wade, Sharon H. Alford, Lawrence C. Brody, and Andreas D. Baxevanis
Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through γδ T-cell IL-17 production in a murine model of sepsis, Kevin R. Kasten, Priya S. Prakash, Jacqueline Unsinger, Holly S. Goetzman, Lisa G. England, Cindy M. Cave, Aaron P. Seitz, Cristina N. Mazuski, Tony T. Zhou, Michel Morre, Richard S. Hotchkiss, David A. Hildeman, and Charles C. Caldwell
Examination of Type IV Pilus Expression and Pilus-Associated Phenotypes in Kingella kingae Clinical Isolates, Thomas E. Kehl-Fie, Eric A. Porsch, Pablo Yagupsky, Elizabeth A. Grass, Caroline Obert, Daniel K. Benjamin Jr, and Joseph W. St. Geme III
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function, Susan M. Kennedy, Nicholas O. Davidson, Sebastian Zeissig, Stephanie K. Dougan, Duarte C. Barral, Yvonne Junker, Zhangguo Chen, Arthur Kaser, Madelyn Ho, Hannah Mandel, Adam McIntyre, Gavin F. Painter, Natacha Veerapen, Gurdyal S. Besra, and et al
Healthy coping: issues and implications in diabetes education and care, Dan Kent, Linda Haas, David Randal, Elizabeth Lin, Carolyn T. Thorpe, Suzanne A. Boren, Jan Fisher, Joan Heins, Patrick Lustman, Joe Nelson, Laurie Ruggiero, Tim Wysocki, Karen Fitzner, Dawn Sherr, and Annette Lenzi Martin
